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Self-supervised pretraining methods with masked prediction demonstrate remarkable within-dataset performance in skeleton-based action recognition. However, we show that, unlike contrastive learning approaches, they do not produce well-separated clusters. Additionally, these methods struggle with generalization in few-shot settings. To address these issues, we propose Self-supervised Tuning for 3D Action Recognition in Skeleton sequences (STARS). Specifically, STARS first uses a masked prediction stage using an encoder-decoder architecture. It then employs nearest-neighbor contrastive learning to partially tune the weights of the encoder, enhancing the formation of semantic clusters for different actions. By tuning the encoder for a few epochs, and without using hand-crafted data augmentations, STARS achieves state-of-the-art self-supervised results in various benchmarks, including NTU-60, NTU-120, and PKU-MMD. In addition, STARS exhibits significantly better results than masked prediction models in few-shot settings, where the model has not seen the actions throughout pretraining. Project page: https://soroushmehraban.github.io/stars/

Visual attention modeling, important for interpreting and prioritizing visual stimuli, plays a significant role in applications such as marketing, multimedia, and robotics. Traditional saliency prediction models, especially those based on Convolutional Neural Networks (CNNs) or Transformers, achieve notable success by leveraging large-scale annotated datasets. However, the current state-of-the-art (SOTA) models that use Transformers are computationally expensive. Additionally, separate models are often required for each image type, lacking a unified approach. In this paper, we propose Saliency Unification through Mamba (SUM), a novel approach that integrates the efficient long-range dependency modeling of Mamba with U-Net to provide a unified model for diverse image types. Using a novel Conditional Visual State Space (C-VSS) block, SUM dynamically adapts to various image types, including natural scenes, web pages, and commercial imagery, ensuring universal applicability across different data types. Our comprehensive evaluations across five benchmarks demonstrate that SUM seamlessly adapts to different visual characteristics and consistently outperforms existing models. These results position SUM as a versatile and powerful tool for advancing visual attention modeling, offering a robust solution universally applicable across different types of visual content.

This study investigates the application of general human motion encoders trained on large-scale human motion datasets for analyzing gait patterns in PD patients. Although these models have learned a wealth of human biomechanical knowledge, their effectiveness in analyzing pathological movements, such as parkinsonian gait, has yet to be fully validated. We propose a comparative framework and evaluate six pre-trained state-of-the-art human motion encoder models on their ability to predict the Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS-III) gait scores from motion capture data. We compare these against a traditional gait feature-based predictive model in a recently released large public PD dataset, including PD patients on and off medication. The feature-based model currently shows higher weighted average accuracy, precision, recall, and F1-score. Motion encoder models with closely comparable results demonstrate promise for scalability and efficiency in clinical settings. This potential is underscored by the enhanced performance of the encoder model upon fine-tuning on PD training set. Four of the six human motion models examined provided prediction scores that were significantly different between on- and off-medication states. This finding reveals the sensitivity of motion encoder models to nuanced clinical changes. It also underscores the necessity for continued customization of these models to better capture disease-specific features, thereby reducing the reliance on labor-intensive feature engineering. Lastly, we establish a benchmark for the analysis of skeleton-based motion encoder models in clinical settings. To the best of our knowledge, this is the first study to provide a benchmark that enables state-of-the-art models to be tested and compete in a clinical context. Codes and benchmark leaderboard are available at code.

Recent transformer-based approaches have demonstrated excellent performance in 3D human pose estimation. However, they have a holistic view and by encoding global relationships between all the joints, they do not capture the local dependencies precisely. In this paper, we present a novel Attention-GCNFormer (AGFormer) block that divides the number of channels by using two parallel transformer and GCNFormer streams. Our proposed GCNFormer module exploits the local relationship between adjacent joints, outputting a new representation that is complementary to the transformer output. By fusing these two representation in an adaptive way, AGFormer exhibits the ability to better learn the underlying 3D structure. By stacking multiple AGFormer blocks, we propose MotionAGFormer in four different variants, which can be chosen based on the speed-accuracy trade-off. We evaluate our model on two popular benchmark datasets: Human3.6M and MPI-INF-3DHP. MotionAGFormer-B achieves state-of-the-art results, with P1 errors of 38.4mm and 16.2mm, respectively. Remarkably, it uses a quarter of the parameters and is three times more computationally efficient than the previous leading model on Human3.6M dataset. Code and models are available at https://github.com/TaatiTeam/MotionAGFormer.

Video-based ambient monitoring of gait for older adults with dementia has the potential to detect negative changes in health and allow clinicians and caregivers to intervene early to prevent falls or hospitalizations. Computer vision-based pose tracking models can process video data automatically and extract joint locations; however, publicly available models are not optimized for gait analysis on older adults or clinical populations. In this work we train a deep neural network to map from a two dimensional pose sequence, extracted from a video of an individual walking down a hallway toward a wall-mounted camera, to a set of three-dimensional spatiotemporal gait features averaged over the walking sequence. The data of individuals with dementia used in this work was captured at two sites using a wall-mounted system to collect the video and depth information used to train and evaluate our model. Our Pose2Gait model is able to extract velocity and step length values from the video that are correlated with the features from the depth camera, with Spearman's correlation coefficients of .83 and .60 respectively, showing that three dimensional spatiotemporal features can be predicted from monocular video. Future work remains to improve the accuracy of other features, such as step time and step width, and test the utility of the predicted values for detecting meaningful changes in gait during longitudinal ambient monitoring., Comment: 14 pages, 3 figures. Code is available at https://github.com/TaatiTeam/pose2gait_public . To be published at the Ambient Intelligence for Health Care Workshop at MICCAI 2023

The quest for human imitative AI has been an enduring topic in AI research since its inception. The technical evolution and emerging capabilities of the latest cohort of large language models (LLMs) have reinvigorated the subject beyond academia to the cultural zeitgeist. While recent NLP evaluation benchmark tasks test some aspects of human-imitative behaviour (e.g., BIG-bench's 'human-like behavior' tasks), few, if not none, examine creative problem solving abilities. Creative problem solving in humans is a well-studied topic in cognitive neuroscience with standardized tests that predominantly use the ability to associate (heterogeneous) connections among clue words as a metric for creativity. Exposure to misleading stimuli - distractors dubbed red herrings - impede human performance in such tasks via the fixation effect and Einstellung paradigm. In cognitive neuroscience studies, such fixations are experimentally induced by pre-exposing participants to orthographically similar incorrect words to subsequent word-fragments or clues. The popular British quiz show Only Connect's Connecting Wall segment essentially mimics Mednick's Remote Associates Test (RAT) formulation with built-in, deliberate red herrings, which makes it an ideal proxy dataset to explore and study fixation effect and Einstellung paradigm from cognitive neuroscience in LLMs. In this paper we present the novel Only Connect Wall (OCW) dataset and report results from our evaluation of selected pre-trained language models and LLMs on creative problem solving tasks like grouping clue words by heterogeneous connections, and identifying correct open knowledge domain connections in respective groups. We synthetically generate two additional datasets: OCW-Randomized, OCW-WordNet to further analyze our red-herrings hypothesis in language models. The code and link to the dataset are available at https://github.com/TaatiTeam/OCW., Comment: v4,v3: Mincor cosmetic adjustments, typo-fixes etc. from V2. Fixed Fig. 2 caption overlapping with text in S2.2. V2: with added OCW-Randomized and OCW-WordNet results in Section 4.3 (added). 22 pages with Appendix

The analysis of speech measures in individuals with amyotrophic lateral sclerosis (ALS) can provide essential information for early diagnosis and tracking disease progression. However, current methods for extracting speech and pause features are manual or semi-automatic, which makes them time-consuming and labour-intensive. The advent of speech-text alignment algorithms provides an opportunity for inexpensive, automated, and accurate analysis of speech measures in individuals with ALS. There is a need to validate speech and pause features calculated by these algorithms against current gold standard methods. In this study, we extracted 8 speech/pause features from 646 audio files of individuals with ALS and healthy controls performing passage reading. Two pretrained forced alignment models - one using transformers and another using a Gaussian mixture / hidden Markov architecture - were used for automatic feature extraction. The results were then validated against semi-automatic speech/pause analysis software, with further subgroup analyses based on audio quality and disease severity. Features extracted using transformer-based forced alignment had the highest agreement with gold standards, including in terms of audio quality and disease severity. This study lays the groundwork for future intelligent diagnostic support systems for clinicians, and for novel methods of tracking disease progression remotely from home., Comment: 2022 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)

Computer vision techniques can help automate or partially automate clinical examination of orofacial impairments to provide accurate and objective assessments. Towards the development of such automated systems, we evaluated two approaches to detect and temporally segment (parse) repetitions in orofacial assessment videos. Recorded videos of participants with amyotrophic lateral sclerosis (ALS) and healthy control (HC) individuals were obtained from the Toronto NeuroFace Dataset. Two approaches for repetition detection and parsing were examined: one based on engineered features from tracked facial landmarks and peak detection in the distance between the vermilion-cutaneous junction of the upper and lower lips (baseline analysis), and another using a pre-trained transformer-based deep learning model called RepNet (Dwibedi et al, 2020), which automatically detects periodicity, and parses periodic and semi-periodic repetitions in video data. In experimental evaluation of two orofacial assessments tasks, - repeating maximum mouth opening (OPEN) and repeating the sentence "Buy Bobby a Puppy" (BBP) - RepNet provided better parsing than the landmark-based approach, quantified by higher mean intersection-over-union (IoU) with respect to ground truth manual parsing. Automated parsing using RepNet also clearly separated HC and ALS participants based on the duration of BBP repetitions, whereas the landmark-based method could not., Comment: 2022 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)

Drug-induced parkinsonism affects many older adults with dementia, often causing gait disturbances. New advances in vision-based human pose-estimation have opened possibilities for frequent and unobtrusive analysis of gait in residential settings. This work leverages novel spatial-temporal graph convolutional network (ST-GCN) architectures and training procedures to predict clinical scores of parkinsonism in gait from video of individuals with dementia. We propose a two-stage training approach consisting of a self-supervised pretraining stage that encourages the ST-GCN model to learn about gait patterns before predicting clinical scores in the finetuning stage. The proposed ST-GCN models are evaluated on joint trajectories extracted from video and are compared against traditional (ordinal, linear, random forest) regression models and temporal convolutional network baselines. Three 2D human pose-estimation libraries (OpenPose, Detectron, AlphaPose) and the Microsoft Kinect (2D and 3D) are used to extract joint trajectories of 4787 natural walking bouts from 53 older adults with dementia. A subset of 399 walks from 14 participants is annotated with scores of parkinsonism severity on the gait criteria of the Unified Parkinson's Disease Rating Scale (UPDRS) and the Simpson-Angus Scale (SAS). Our results demonstrate that ST-GCN models operating on 3D joint trajectories extracted from the Kinect consistently outperform all other models and feature sets. Prediction of parkinsonism scores in natural walking bouts of unseen participants remains a challenging task, with the best models achieving macro-averaged F1-scores of 0.53 +/- 0.03 and 0.40 +/- 0.02 for UPDRS-gait and SAS-gait, respectively. Pre-trained model and demo code for this work is available: https://github.com/TaatiTeam/stgcn_parkinsonism_prediction.

Although pain is frequent in old age, older adults are often undertreated for pain. This is especially the case for long-term care residents with moderate to severe dementia who cannot report their pain because of cognitive impairments that accompany dementia. Nursing staff acknowledge the challenges of effectively recognizing and managing pain in long-term care facilities due to lack of human resources and, sometimes, expertise to use validated pain assessment approaches on a regular basis. Vision-based ambient monitoring will allow for frequent automated assessments so care staff could be automatically notified when signs of pain are displayed. However, existing computer vision techniques for pain detection are not validated on faces of older adults or people with dementia, and this population is not represented in existing facial expression datasets of pain. We present the first fully automated vision-based technique validated on a dementia cohort. Our contributions are threefold. First, we develop a deep learning-based computer vision system for detecting painful facial expressions on a video dataset that is collected unobtrusively from older adult participants with and without dementia. Second, we introduce a pairwise comparative inference method that calibrates to each person and is sensitive to changes in facial expression while using training data more efficiently than sequence models. Third, we introduce a fast contrastive training method that improves cross-dataset performance. Our pain estimation model outperforms baselines by a wide margin, especially when evaluated on faces of people with dementia. Pre-trained model and demo code available at https://github.com/TaatiTeam/pain_detection_demo

Orofacial deficits are common in people with Parkinson's disease (PD) and their evolution might represent an important biomarker of disease progression. We are developing an automated system for assessment of orofacial function in PD that can be used in-home or in-clinic and can provide useful and objective clinical information that informs disease management. Our current approach relies on color and depth cameras for the estimation of 3D facial movements. However, depth cameras are not commonly available, might be expensive, and require specialized software for control and data processing. The objective of this paper was to evaluate if depth cameras are needed to differentiate between healthy controls and PD patients based on features extracted from orofacial kinematics. Results indicate that 2D features, extracted from color cameras only, are as informative as 3D features, extracted from color and depth cameras, differentiating healthy controls from PD patients. These results pave the way for the development of a universal system for automatic and objective assessment of orofacial function in PD., Comment: 4 pages, 1 table

Importance: Machine learning (ML) approaches to facial landmark localization carry great clinical potential for quantitative assessment of facial function as they enable high-throughput automated quantification of relevant facial metrics from photographs. However, translation from research settings to clinical applications requires important improvements. Objective: To develop an ML algorithm for accurate facial landmarks localization in photographs of facial palsy patients, and use it as part of an automated computer-aided diagnosis system. Design, Setting, and Participants: Facial landmarks were manually localized in portrait photographs of eight expressions obtained from 200 facial palsy patients and 10 controls. A novel ML model for automated facial landmark localization was trained using this disease-specific database. Model output was compared to manual annotations and the output of a model trained using a larger database consisting only of healthy subjects. Model accuracy was evaluated by the normalized root mean square error (NRMSE) between algorithms' prediction and manual annotations. Results: Publicly available algorithms provide poor results when applied to patients compared to healthy controls (NRMSE, 8.56 +/- 2.16 vs. 7.09 +/- 2.34, p << 0.01). We found significant improvement in facial landmark localization accuracy for the clinical population when using a model trained with a relatively small number patients' photographs (1440) compared to a model trained using several thousand more images of healthy faces (NRMSE, 6.03 +/- 2.43 vs. 8.56 +/- 2.16, p << 0.01). Conclusions: Retraining a landmark detection model with a small number of clinical images significantly improved landmark detection performance in frontal view photographs of the clinical population. These results represent the first steps towards an automatic system for computer-aided assessment in facial palsy., Comment: 21 pages, 4 figures, 1 table

Accurate facial expression analysis is an essential step in various clinical applications that involve physical and mental health assessments of older adults (e.g. diagnosis of pain or depression). Although remarkable progress has been achieved toward developing robust facial landmark detection methods, state-of-the-art methods still face many challenges when encountering uncontrolled environments, different ranges of facial expressions, and different demographics of the population. A recent study has revealed that the health status of individuals can also affect the performance of facial landmark detection methods on front views of faces. In this work, we investigate this matter in a much greater context using seven facial landmark detection methods. We perform our evaluation not only on frontal faces but also on profile faces and in various regions of the face. Our results shed light on limitations of the existing methods and challenges of applying these methods in clinical settings by indicating: 1) a significant difference between the performance of state-of-the-art when tested on the profile or frontal faces of individuals with vs. without dementia; 2) insights on the existing bias for all regions of the face; and 3) the presence of this bias despite re-training/fine-tuning with various configurations of six datasets., Comment: Face and Gesture Analysis for Health Informatics (FGAHI) Workshop at CVPR 2019

In recent years, supervised machine learning models have demonstrated tremendous success in a variety of application domains. Despite the promising results, these successful models are data hungry and their performance relies heavily on the size of training data. However, in many healthcare applications it is difficult to collect sufficiently large training datasets. Transfer learning can help overcome this issue by transferring the knowledge from readily available datasets (source) to a new dataset (target). In this work, we propose a hybrid instance-based transfer learning method that outperforms a set of baselines including state-of-the-art instance-based transfer learning approaches. Our method uses a probabilistic weighting strategy to fuse information from the source domain to the model learned in the target domain. Our method is generic, applicable to multiple source domains, and robust with respect to negative transfer. We demonstrate the effectiveness of our approach through extensive experiments for two different applications., Comment: Machine Learning for Health (ML4H) Workshop at NeurIPS 2018 arXiv:cs/0101200

Medical imaging machine learning algorithms are usually evaluated on a single dataset. Although training and testing are performed on different subsets of the dataset, models built on one study show limited capability to generalize to other studies. While database bias has been recognized as a serious problem in the computer vision community, it has remained largely unnoticed in medical imaging research. Transfer learning thus remains confined to the re-use of feature representations requiring re-training on the new dataset. As a result, machine learning models do not generalize even when trained on imaging datasets that were captured to study the same variable of interest. The ability to transfer knowledge gleaned from one study to another, without the need for re-training, if possible, would provide reassurance that the models are learning knowledge fundamental to the problem under study instead of latching onto the idiosyncracies of a dataset. In this paper, we situate the problem of dataset bias in the context of medical imaging studies. We show empirical evidence that such a problem exists in medical datasets. We then present a framework to unlearn study membership as a means to handle the problem of database bias. Our main idea is to take the data from the original feature space to an intermediate space where the data points are indistinguishable in terms of which study they come from, while maintaining the recognition capability with respect to the variable of interest. This will promote models which learn the more general properties of the etiology under study instead of aligning to dataset-specific peculiarities. Essentially, our proposed model learns to unlearn the dataset bias., Comment: Machine Learning for Health (ML4H) Workshop at NeurIPS 2018 arXiv:1811.07216 Submission Id: 207

Active appearance models (AAMs) are a class of generative models that have seen tremendous success in face analysis. However, model learning depends on the availability of detailed annotation of canonical landmark points. As a result, when accurate AAM fitting is required on a different set of variations (expression, pose, identity), a new dataset is collected and annotated. To overcome the need for time consuming data collection and annotation, transfer learning approaches have received recent attention. The goal is to transfer knowledge from previously available datasets (source) to a new dataset (target). We propose a subspace transfer learning method, in which we select a subspace from the source that best describes the target space. We propose a metric to compute the directional similarity between the source eigenvectors and the target subspace. We show an equivalence between this metric and the variance of target data when projected onto source eigenvectors. Using this equivalence, we select a subset of source principal directions that capture the variance in target data. To define our model, we augment the selected source subspace with the target subspace learned from a handful of target examples. In experiments done on six publicly available datasets, we show that our approach outperforms the state of the art in terms of the RMS fitting error as well as the percentage of test examples for which AAM fitting converges to the ground truth., Comment: Copyright IEEE. To be published in the proceedings of International Joint Conference on Biometrics (IJCB) 2017

Objective: To apply deep learning pose estimation algorithms for vision-based assessment of parkinsonism and levodopa-induced dyskinesia (LID). Methods: Nine participants with Parkinson's disease (PD) and LID completed a levodopa infusion protocol, where symptoms were assessed at regular intervals using the Unified Dyskinesia Rating Scale (UDysRS) and Unified Parkinson's Disease Rating Scale (UPDRS). A state-of-the-art deep learning pose estimation method was used to extract movement trajectories from videos of PD assessments. Features of the movement trajectories were used to detect and estimate the severity of parkinsonism and LID using random forest. Communication and drinking tasks were used to assess LID, while leg agility and toe tapping tasks were used to assess parkinsonism. Feature sets from tasks were also combined to predict total UDysRS and UPDRS Part III scores. Results: For LID, the communication task yielded the best results for dyskinesia (severity estimation: r = 0.661, detection: AUC = 0.930). For parkinsonism, leg agility had better results for severity estimation (r = 0.618), while toe tapping was better for detection (AUC = 0.773). UDysRS and UPDRS Part III scores were predicted with r = 0.741 and 0.530, respectively. Conclusion: This paper presents the first application of deep learning for vision-based assessment of parkinsonism and LID and demonstrates promising performance for the future translation of deep learning to PD clinical practices. Significance: The proposed system provides insight into the potential of computer vision and deep learning for clinical application in PD., Comment: 8 pages, 1 figure. Under review

Because falls are funny, YouTube and other video sharing sites contain a large repository of real-life falls. We propose extracting gait and balance information from these videos to help us better understand some of the factors that contribute to falls. Proof-of-concept is explored in a single video containing multiple (n=14) falls/non-falls in the presence of an unexpected obstacle. The analysis explores: computing spatiotemporal parameters of gait in a video captured from an arbitrary viewpoint; the relationship between parameters of gait from the last few steps before the obstacle and falling vs. not falling; and the predictive capacity of a multivariate model in predicting a fall in the presence of an unexpected obstacle. Homography transformations correct the perspective projection distortion and allow for the consistent tracking of gait parameters as an individual walks in an arbitrary direction in the scene. A synthetic top view allows for computing the average stride length and a synthetic side view allows for measuring up and down motions of the head. In leave-one-out cross-validation, we were able to correctly predict whether a person would fall or not in 11 out of the 14 cases (78.6%), just by looking at the average stride length and the range of vertical head motion during the 1-4 most recent steps prior to reaching the obstacle., Comment: 4 pages, 3 figures, 2 tables

A fall is an abnormal activity that occurs rarely, so it is hard to collect real data for falls. It is, therefore, difficult to use supervised learning methods to automatically detect falls. Another challenge in using machine learning methods to automatically detect falls is the choice of engineered features. In this paper, we propose to use an ensemble of autoencoders to extract features from different channels of wearable sensor data trained only on normal activities. We show that the traditional approach of choosing a threshold as the maximum of the reconstruction error on the training normal data is not the right way to identify unseen falls. We propose two methods for automatic tightening of reconstruction error from only the normal activities for better identification of unseen falls. We present our results on two activity recognition datasets and show the efficacy of our proposed method against traditional autoencoder models and two standard one-class classification methods., Comment: 25 pages, 6 figures, 4 Tables

A novel multi-scale operator for unorganized 3D point clouds is introduced. The Difference of Normals (DoN) provides a computationally efficient, multi-scale approach to processing large unorganized 3D point clouds. The application of DoN in the multi-scale filtering of two different real-world outdoor urban LIDAR scene datasets is quantitatively and qualitatively demonstrated. In both datasets the DoN operator is shown to segment large 3D point clouds into scale-salient clusters, such as cars, people, and lamp posts towards applications in semi-automatic annotation, and as a pre-processing step in automatic object recognition. The application of the operator to segmentation is evaluated on a large public dataset of outdoor LIDAR scenes with ground truth annotations., Comment: To be published in proceedings of 3DIMPVT 2012