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357 results on '"Tai, Chen-Jei"'

8. Anti-inflammatory effect of euphane- and tirucallane-type triterpenes isolated from the traditional herb Euphorbia neriifolia L

Author

Chang, Stephen S., primary, Huang, Hung-Tse, additional, Wei, Wen-Chi, additional, Lo, I-Wen, additional, Lin, Yu-Chi, additional, Chao, Chih-Hua, additional, Liao, Geng-You, additional, Shen, Yuh-Chiang, additional, Chen, Jih-Jung, additional, Li, Tsung-Lin, additional, Lin, Liang-Tzung, additional, Tai, Chen-Jei, additional, Kuo, Yao-Haur, additional, and Liaw, Chia-Ching, additional

Published
2023
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33. Decision-making process for choosing an elective cesarean delivery among primiparas in Taiwan

Author

Huang, Shiou-Yun, Sheu, Shuh-Jen, Tai, Chen-Jei, Chiang, Ching-Ping, and Chien, Li-Yin

Subjects
Cesarean section -- Social aspects -- Complications and side effects, Decision-making -- Health aspects, Health risk assessment -- Methods -- Social aspects, Health care industry
Abstract

A significant proportion of cesarean deliveries in Taiwan were without medical indications and/or on maternal request. The purpose of this study was to understand the decision-making process of choosing an elective cesarean delivery (ELCD) among primiparas in Taiwan. This qualitative exploratory study was guided by grounded theory. Data were collected through in-depth interviews with 20 primiparous women, 15 of whom chose ELCD. Verbatim transcriptions were analyzed using constant comparative analysis and methods of open, axial, and selective coding. The core category that describes the process of ELCD decision making among primiparas is 'controlling risks of childbirth and ensuring well-being.' The decision process can be divided into three phases: (1) Pre-decision: risk perception, including two subcategories, negative pre-existing ideas about normal spontaneous delivery (NSD) caused worry, and desire for ELCD as the solution; (2) In-decision: risk assessment. Women proactively collected information about NSD and cesarean delivery, and then weighed the personal risk between NSD and ELCD. Risk assessment focused on seven dimensions including safety, health, comfort, efficiency, feminine charms, time and economy; (3) Post-decision: marching onward fearlessly, including two subcategories, belief in ELCD and stress relief, and persuading stakeholders to agree and gaining the required resources for ELCD. At different phases of decision-making, women revealed different concerns, though the sequence of phases was not necessarily unidirectional. Health care providers should be aware of the decision phase and intervene at appropriate times. It is difficult to change a women's decision to have ELCD in the post-decision phase. Keywords Decision making * Primiparas * Elective cesarean delivery * Risk perception * Childbirth * Pregnancy, Introduction With advances in medical technology and changes in the social environment, cesarean delivery has gradually evolved from a life-saving operation to a common mode of delivery [1]. The rate [...]

Published
2013
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36. Probiotics-Derived Extracellular Vesicles Protect Oxidative Stress against H 2 O 2 Induction in Placental Cells.

Author

Wang, Le-Ming, Lee, Bao-Hong, Hou, Chih-Yao, Hsu, Wei-Hsuan, and Tai, Chen-Jei

Subjects
EXTRACELLULAR vesicles, OXIDATIVE stress, CELLULAR aging, LACTIC acid bacteria, PREMATURE labor, CELL death
Abstract

(1) Background: The microbial phase in the vaginal environment has been found to regulate the physiological activity of host cells. Studies have demonstrated that abnormal microbial growth in the vagina and a significant reduction in the proportion of lactic acid bacteria promote the occurrence of spontaneous preterm birth (sPTB). However, the contributing mechanism remains unknown. (2) Methods: This study uses extracellular vesicles (EVs) secreted by the probiotic Lactobacillus crispatus, commonly found in the vagina, to explore their potential to attenuate placental cells caused by oxidative stress induction. (3) Results: We found that L. crispatus-derived EVs improved Akt phosphorylation and attenuated both cell senescence and death in placental cells caused by oxidative stress induction. In addition, L. crispatus-derived EVs enhanced the resistance to H2O2 induction mediated by increasing mitochondrial fusion. (4) Conclusion: This is the first study to demonstrate that L. crispatus in the vagina can not only regulate the physiological functions of placental cells through the delivery of L. crispatus-EVs but also reduce cell senescence. As cell senescence is related to the occurrence of sPTB, these results indicate that maintaining the population of L. crispatus in the vaginal environment should be an adjuvant treatment strategy to avoid sPTB. [ABSTRACT FROM AUTHOR]

Published
2022
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