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3 results on '"Tai-Jiang, Liu"'

1. Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies a susceptibility locus at PLCE1

Author

Han Jing Wang, Wu Wei, Wen Yan Cui, Fu Sheng Gao, Zeng Lin Fan, Yu Jing Fan, Chang Dong Lu, Yan Rui Zhang, Jin Chang Wei, Fu Bao Chang, Qing Peng Kong, Lian Qun Zhang, Guo Lan Xing, Na Liu, Qin Xian Zhang, Hou-Feng Zheng, Jin Sheng Wang, Xiao Shan Feng, Zhi Ming Cai, Jie Zhi Yang, Liang Wang, Li Guo, Shi Yong Lian, Wen Jun Gao, Ling Yuan, En Min Li, Ran Wang, Xiao Mei Lu, Feng Li, Guang Yan Lei, Yan Wang, Xin He, Min Han, Hong Qi, Qirenwang Qige, Dan Li, Xuejun Zhang, Zheng Zhang, Tian Yun Wang, Hai Liu, Sheng Li Zhou, Xue Min Li, Zhou Wang, Zhi Gang Guo, Long Tang Bai, Jian Wei Ku, Bao Ping Chen, Hai Yan Wang, Jing Huang, She Gan Gao, Jin Wang, Jia Huang, Ming Guo, Wen Liang Zhu, Zi Ming Dong, Guang Cheng Ding, Liangdan Sun, Yong Hong Ai, Jun Yan Hong, Zhi Wei Chang, Long Qi Chen, Fu Guo Zhu, Wei Ke Cao, Liu Qin Yang, Jiang Man Li, Chang Wei Feng, Wen Jing Fu, Xin Ying Jiao, Fang Fang Shen, Bin Liu, Tao Guo, Wen Bin Yue, Xing Chuan Li, Ruo Bai Lin, Jin Cheng Dong, Wancai Yang, Jin Yan, Min Liu, Fu You Zhou, Yue Wu, Jie Chen, Xia Yang, Shuang Song, Hong Lei Li, Xiang Zhuang, Zhi Yong Wu, Jing-Li Ren, Ji Li Chen, Zhong Ying Shen, Yue Lu, Yu Lan, Li Yan Xu, Jin Ya Tian, Yin Li, Jian Po Wang, Dong Xie, Jian Jun Miao, Ji Lin Li, Peng Zhang, Qin Lu, Xin Song, Wei Peng Wang, Hai Lin Liu, Song Liang Qiu, Juan Cui, Zong Min Fan, Yi Yuan, Chao Yuan, Guo Qiang Kong, Wen Jun Yang, Tai Jiang Liu, Xue Ke Zhao, Xiu-Min Li, Qi Zhou, Ilyar Sheyhidin, Ying Fa Zhou, Zhi Qin Bao, Xiu Feng Yang, Ai Fang Ji, Shuqing Chen, Zhi Cai Liu, Shu Wei Ren, Xian Bo Zuo, Zhi Qing Yuan, Dong Mei Fan, Li-Dong Wang, Suo Li Han, and Zhiguo Chen

Subjects
Genetics, PLCE1, Genotype, medicine, Adenocarcinoma, Cancer, Genome-wide association study, Single-nucleotide polymorphism, Biology, medicine.disease, Gene, Genome
Abstract

Li Dong Wang and colleagues report a genome wide association study for esophageal squamous cell carcinoma in the Chinese population. They identify two risk loci at PLCE1 and C20orf54.

Published
2010
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2. Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54

Author

Li-Dong, Wang, Fu-You, Zhou, Xue-Min, Li, Liang-Dan, Sun, Xin, Song, Yan, Jin, Jiang-Man, Li, Guo-Qiang, Kong, Hong, Qi, Juan, Cui, Lian-Qun, Zhang, Jie-Zhi, Yang, Ji-Lin, Li, Xing-Chuan, Li, Jing-Li, Ren, Zhi-Cai, Liu, Wen-Jun, Gao, Ling, Yuan, Wu, Wei, Yan-Rui, Zhang, Wei-Peng, Wang, Ilyar, Sheyhidin, Feng, Li, Bao-Ping, Chen, Shu-Wei, Ren, Bin, Liu, Dan, Li, Jian-Wei, Ku, Zong-Min, Fan, Sheng-Li, Zhou, Zhi-Gang, Guo, Xue-Ke, Zhao, Na, Liu, Yong-Hong, Ai, Fang-Fang, Shen, Wen-Yan, Cui, Shuang, Song, Tao, Guo, Jing, Huang, Chao, Yuan, Jia, Huang, Yue, Wu, Wen-Bin, Yue, Chang-Wei, Feng, Hong-Lei, Li, Yan, Wang, Jin-Ya, Tian, Yue, Lu, Yi, Yuan, Wen-Liang, Zhu, Min, Liu, Wen-Jing, Fu, Xia, Yang, Han-Jing, Wang, Suo-Li, Han, Jie, Chen, Min, Han, Hai-Yan, Wang, Peng, Zhang, Xiu-Min, Li, Jin-Cheng, Dong, Guo-Lan, Xing, Ran, Wang, Ming, Guo, Zhi-Wei, Chang, Hai-Lin, Liu, Li, Guo, Zhi-Qing, Yuan, Hai, Liu, Qin, Lu, Liu-Qin, Yang, Fu-Guo, Zhu, Xiu-Feng, Yang, Xiao-Shan, Feng, Zhou, Wang, Yin, Li, She-Gan, Gao, Qirenwang, Qige, Long-Tang, Bai, Wen-Jun, Yang, Guang-Yan, Lei, Zhong-Ying, Shen, Long-Qi, Chen, En-Min, Li, Li-Yan, Xu, Zhi-Yong, Wu, Wei-Ke, Cao, Jian-Po, Wang, Zhi-Qin, Bao, Ji-Li, Chen, Guang-Cheng, Ding, Xiang, Zhuang, Ying-Fa, Zhou, Hou-Feng, Zheng, Zheng, Zhang, Xian-Bo, Zuo, Zi-Ming, Dong, Dong-Mei, Fan, Xin, He, Jin, Wang, Qi, Zhou, Qin-Xian, Zhang, Xin-Ying, Jiao, Shi-Yong, Lian, Ai-Fang, Ji, Xiao-Mei, Lu, Jin-Sheng, Wang, Fu-Bao, Chang, Chang-Dong, Lu, Zhi-Guo, Chen, Jian-Jun, Miao, Zeng-Lin, Fan, Ruo-Bai, Lin, Tai-Jiang, Liu, Jin-Chang, Wei, Qing-Peng, Kong, Yu, Lan, Yu-Jing, Fan, Fu-Sheng, Gao, Tian-Yun, Wang, Dong, Xie, Shu-Qing, Chen, Wan-Cai, Yang, Jun-Yan, Hong, Liang, Wang, Song-Liang, Qiu, Zhi-Ming, Cai, and Xue-Jun, Zhang

Subjects
Male, Esophageal Neoplasms, Chromosomes, Human, Pair 10, Chromosomes, Human, Pair 20, Membrane Proteins, Membrane Transport Proteins, Middle Aged, Polymorphism, Single Nucleotide, Phosphoinositide Phospholipase C, Asian People, Genetic Loci, Case-Control Studies, Carcinoma, Squamous Cell, Humans, Female, Genetic Predisposition to Disease, Aged, Genome-Wide Association Study
Abstract

We performed a genome-wide association study of esophageal squamous cell carcinoma (ESCC) by genotyping 1,077 individuals with ESCC and 1,733 control subjects of Chinese Han descent. We selected 18 promising SNPs for replication in an additional 7,673 cases of ESCC and 11,013 control subjects of Chinese Han descent and 303 cases of ESCC and 537 control subjects of Chinese Uygur-Kazakh descent. We identified two previously unknown susceptibility loci for ESCC: PLCE1 at 10q23 (P(Han combined for ESCC) = 7.46 x 10(-56), odds ratio (OR) = 1.43; P(Uygur-Kazakh for ESCC) = 5.70 x 10(-4), OR = 1.53) and C20orf54 at 20p13 (P(Han combined for ESCC) = 1.21 x 10(-11), OR = 0.86; P(Uygur-Kazakh for ESCC) = 7.88 x 10(-3), OR = 0.66). We also confirmed association in 2,766 cases of gastric cardia adenocarcinoma cases and the same 11,013 control subjects (PLCE1, P(Han for GCA) = 1.74 x 10(-39), OR = 1.55 and C20orf54, P(Han for GCA) = 3.02 x 10(-3), OR = 0.91). PLCE1 and C20orf54 have important biological implications for both ESCC and GCA. PLCE1 might regulate cell growth, differentiation, apoptosis and angiogenesis. C20orf54 is responsible for transporting riboflavin, and deficiency of riboflavin has been documented as a risk factor for ESCC and GCA.

Published
2010

3. Corrigendum: Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54

Author

Ji-Li Chen, Feng Li, Zhi-Yong Wu, Yan Wang, Xiu-Feng Yang, Tai-Jiang Liu, Shi-Yong Lian, Lian-Qun Zhang, Ilyar Sheyhidin, Xiu-Min Li, Jin-Chang Wei, Zhao Xueke, Tao Guo, Chang-Wei Feng, Xin He, Li-Yan Xu, Zhou Wang, Xing-Chuan Li, Qi Zhou, Fu-Guo Zhu, Ruo-Bai Lin, Haiyan Wang, Hou-Feng Zheng, Jin-Cheng Dong, Xiang Zhuang, Zheng Zhang, Hong-Lei Li, Yong-Hong Ai, Wen-Yan Cui, Zhou Fuyou, Liangdan Sun, Ying-Fa Zhou, Shengli Zhou, Qin-Xian Zhang, Shu-Wei Ren, Jian-Wei Ku, Yan-Rui Zhang, Yue Wu, Yue Lu, Yu Lan, Li Guo, Jian-Jun Miao, Dong Xie, Zhi-Wei Chang, Song-Liang Qiu, Qirenwang Qige, Jia Huang, Xianbo Zuo, She-Gan Gao, Qing-Peng Kong, Bin Liu, Li-Dong Wang, Wen-Jing Fu, Zhong-Ying Shen, Xue-Min Li, Tian-Yun Wang, Jun-Yan Hong, Wen Jun Gao, Guang-Yan Lei, Ji-Lin Li, Xin Song, Jin-Ya Tian, Guo-Lan Xing, Xiao-Shan Feng, Min Han, Guang-Cheng Ding, Fu-Bao Chang, Na Liu, Zhiguo Chen, Hai Liu, Fang-Fang Shen, Ran Wang, Wen-Jun Yang, Peng Zhang, Xia Yang, Qin Lu, Wancai Yang, Jin Yan, Wei Peng Wang, Juan Cui, Shuang Song, Dong-Mei Fan, Yi Yuan, Zhi-Qing Yuan, En-Min Li, Wu Wei, Ai-Fang Ji, Suo-Li Han, Jie-Zhi Yang, Han-Jing Wang, Yu-Jing Fan, Jin Wang, Ming Guo, Wen-Bin Yue, Wen Liang Zhu, Long-Qi Chen, Jing-Li Ren, Jing Huang, Jin-Sheng Wang, Liu Qin Yang, Liang Wang, Xuejun Zhang, Xiao-Mei Lu, Dan Li, Zi-Ming Dong, Guo-Qiang Kong, Zeng-Lin Fan, Ling Yuan, Jian-Po Wang, Yin Li, Zhi-Gang Guo, Chao Yuan, Bao-Ping Chen, Jiang-Man Li, Hai Lin Liu, Long-Tang Bai, Xin-Ying Jiao, Hong Qi, Zhi-Cai Liu, Zong-Min Fan, Jie Chen, Zhi-Ming Cai, Fu-Sheng Gao, Min Liu, Shuqing Chen, Changdong Lu, Zhi-Qin Bao, and Wei-Ke Cao

Subjects
Oncology, medicine.medical_specialty, PLCE1, Genome-wide association study, Joint analysis, Biology, Esophageal squamous cell carcinoma, Original data, Internal medicine, Genetics, medicine, Cancer research, Susceptibility locus, Chinese subjects
Abstract

Nat. Genet. 42, 759–763 (2010); published online 22 August 2010; corrected after print 27 August 2014 In contrast to the version of this article initially published, the authors now find no evidence to support association with esophageal squamous cell carcinoma susceptibility for rs13042395[T] at 20p13 in their original data, in two independent sets of cases and controls collected in other Chinese populations or in the joint analysis of these three studies.

Published
2014
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