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2. How to Recover Soil from Mixed Wastes? Separability of Soil and Wastes

Author

Takai, Atsushi, Kato, Tomohiro, Katsumi, Takeshi, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Cui, Zhen-Dong, Series Editor, Duc Long, Phung, editor, and Dung, Nguyen Tien, editor

Published
2024
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3. Anti-integrin αvβ6 autoantibodies in patients with primary sclerosing cholangitis

Author

Yoshida, Hiroyuki, Shiokawa, Masahiro, Kuwada, Takeshi, Muramoto, Yuya, Ota, Sakiko, Nishikawa, Yoshihiro, Maeda, Hirona, Kakiuchi, Nobuyuki, Okamoto, Kanako, Yamazaki, Hajime, Yokode, Masataka, Nakamura, Takeharu, Matsumoto, Shimpei, Hirano, Tomonori, Okada, Hirokazu, Marui, Saiko, Sogabe, Yuko, Matsumori, Tomoaki, Mima, Atsushi, Uza, Norimitsu, Eso, Yuji, Takai, Atsushi, Takahashi, Ken, Ueda, Yoshihide, Kodama, Yuzo, Chiba, Tsutomu, and Seno, Hiroshi

Published
2023
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7. SAT-319 RECAM-J 2023-validation of RECAM and development of the japanese version for the diagnosis of DILI

Author

Tanaka, Atsushi, primary, Tsuji, Keiji, additional, Komiyama, Yasuyuki, additional, Tsuruya, Kota, additional, Kakisaka, Keisuke, additional, Tsutsui, Akemi, additional, Ichimoto, Keiko, additional, Ueno, Masayuki, additional, Okazaki, Yuki, additional, Kamimura, Hiroteru, additional, Takai, Atsushi, additional, Yamashiki, Noriyo, additional, Ito, Takanori, additional, Watanabe, Masaaki, additional, Abe, Masanori, additional, and Kagawa, Tatehiro, additional

Published
2024
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13. Integrated analyses of the genetic and clinicopathological features of cholangiolocarcinoma: cholangiolocarcinoma may be characterized by mismatch‐repair deficiency

Author

Makino, Kenta, primary, Ishii, Takamichi, additional, Takeda, Haruhiko, additional, Saito, Yoichi, additional, Fujiwara, Yukio, additional, Fujimoto, Masakazu, additional, Ito, Takashi, additional, Wakama, Satoshi, additional, Kumagai, Ken, additional, Munekage, Fumiaki, additional, Horie, Hiroshi, additional, Tomofuji, Katsuhiro, additional, Oshima, Yu, additional, Uebayashi, Elena Yukie, additional, Kawai, Takayuki, additional, Ogiso, Satoshi, additional, Fukumitsu, Ken, additional, Takai, Atsushi, additional, Seno, Hiroshi, additional, and Hatano, Etsuro, additional

Published
2024
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16. RECAM‐J 2023—Validation and development of the Japanese version of RECAM for the diagnosis of drug‐induced liver injury.

Author

Tanaka, Atsushi, Tsuji, Keiji, Komiyama, Yasuyuki, Tsuruya, Kota, Kakisaka, Keisuke, Tsutsui, Akemi, Ichimoto, Keiko, Ueno, Masayuki, Okazaki, Yuki, Kamimura, Hiroteru, Takai, Atsushi, Yamashiki, Noriyo, Ito, Takanori, Watanabe, Masaaki, Abe, Masanori, Harada, Ken‐ichi, and Kagawa, Tatehiro

Subjects
LIVER injuries, DRUG side effects, HEPATITIS A virus, HEPATITIS viruses, VIRAL hepatitis
Abstract

Aim: The diagnosis of drug‐induced liver injury (DILI) is challenging. We modified the revised electronic version of the Roussel Uclaf Causality Assessment Method (RUCAM) for the diagnosis of DILI (RECAM), the scoring system developed in US and Spanish cohorts in 2022, and developed RECAM‐J 2023 to align with the clinical practice in Japan. In the current study, we introduce RECAM‐J 2023 and verify its performance in the context of Japanese patients with DILI. Methods: After translation of RECAM into Japanese, modifications were made to develop RECAM‐J 2023 without any alteration to the scores. To examine the validity and performance of RECAM‐J 2023, clinical information on DILI and non‐DILI cases in Japan were retrospectively collected. The diagnosis of DILI was made by expert's decision. Then we scored each case using RECAM‐J 2023, and calculated area under curve (AUC) values for identification for DILI. Results: We collected data from 538 DILI and 128 non‐DILI cases. The sum of highly probable (HP) and probable (PR) cases categorized by RECAM‐J 2023 were only 206 (38%) in DILI cases. As the primary cause of low scores was the deduction with missing hepatitis virus markers, which is unlikely to be an issue in prospective applications, we rescored without these deductions. At this time, the sum of HP and PR was raised to 421 (78%). The AUCs of RECAM‐J 2023 without deductions were 0.70 and 0.88 for identifying at least HP, and at least PR, respectively. Conclusion: RECAM‐J 2023, when prospectively used without any missing hepatitis virus markers, provides acceptable performance for identifying at least PR DILI cases in Japanese daily clinical practice. [ABSTRACT FROM AUTHOR]

Published
2024
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18. 日本固有の土へのPFOSの吸着特性評価

Author

YOSHIMURA, Hiro, primary, OKADA, Takaomi, additional, TAKAI, Atsushi, additional, KATO, Tomohiro, additional, YUKIOKA, Satoru, additional, TANAKA, Shuhei, additional, YASUTAKA, Tetsuo, additional, and KATSUMI, Takeshi, additional

Published
2024
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23. Pore water pressure prediction for undrained heating of soils

Author

Ghaaowd, Ismaail, Takai, Atsushi, Katsumi, Takeshi, and McCartney, John S

Subjects
energy geotechnics, geomaterial characterisation, testing & evaluation, Civil Engineering, Environmental Engineering
Abstract

This paper focuses on the validation of a prediction model for the thermally induced excess pore water pressure generated in saturated soils during undrained heating. A thermoelastic analysis was calibrated using experimental data presented in the literature for normally consolidated soils having different mineralogical compositions. The magnitude of thermally induced excess pore water pressure for these soils was observed to depend on the initial void ratio, the initial effective stress, the thermal coefficient of cubical expansion of the soil particles, the change in temperature, the compressibility of the soil skeleton and the physicochemical coefficient of structural volume change. An empirical relationship between the physicochemical coefficient of structural volume change and the plasticity index was proposed to predict the thermally induced excess pore water pressure for saturated, normally consolidated soils. To validate the model, an undrained heating test was performed independently on a specimen of normally consolidated kaolinite clay, and the measured thermally induced excess pore water pressures were found to match well with the model predictions.

Published
2017

31. Comprehensive analyses of the clinicopathological features and genomic mutations of combined hepatocellular‐cholangiocarcinoma

Author

Ito, Takashi, primary, Ishii, Takamichi, additional, Takeda, Haruhiko, additional, Sumiyoshi, Shinji, additional, Tomofuji, Katsuhiro, additional, Wakama, Satoshi, additional, Makino, Kenta, additional, Horie, Hiroshi, additional, Kumagai, Ken, additional, Takai, Atsushi, additional, Uebayashi, Elena Yukie, additional, Ogiso, Satoshi, additional, Fukumitsu, Ken, additional, Haga, Hironori, additional, Seno, Hiroshi, additional, and Hatano, Etsuro, additional

Published
2023
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34. Comprehensive analyses of the clinicopathological features and genomic mutations of combined hepatocellular‐cholangiocarcinoma.

Author

Ito, Takashi, Ishii, Takamichi, Takeda, Haruhiko, Sumiyoshi, Shinji, Tomofuji, Katsuhiro, Wakama, Satoshi, Makino, Kenta, Horie, Hiroshi, Kumagai, Ken, Takai, Atsushi, Uebayashi, Elena Yukie, Ogiso, Satoshi, Fukumitsu, Ken, Haga, Hironori, Seno, Hiroshi, and Hatano, Etsuro

Subjects
GENETIC mutation, CLINICAL pathology, LIVER cancer, SEQUENCE analysis, EPIGENETICS
Abstract

Aim: Combined hepatocellular‐cholangiocarcinoma (cHCC‐CCA) is a rare primary liver cancer that has two different tumor phenotypes in a single tumor nodule. The relationship between genetic mutations and clinicopathological features of cHCC‐CCA remains to be elucidated. Methods: Whole‐exome sequencing analyses were carried out in 13 primary and 2 recurrent cHCC‐CCAs. The whole‐exome analyses and clinicopathological information were integrated. Results: TP53 was the most frequently mutated gene in this cohort, followed by BAP1, IDH1/2, and NFE2L2 mutations in multiple cases. All tumors with diameters <3 cm had TP53 mutations. In contrast, six of seven tumors with diameters ≥3 cm did not have TP53 mutations, but all seven tumors had mutations in genes associated with various pathways, including Wnt, RAS/PI3K, and epigenetic modulators. In the signature analysis, the pattern of mutations shown in the TP53 mutation group tended to be more similar to HCC than the TP53 nonmutation group. Mutations in recurrent cHCC‐CCA tumors were frequently identical to those in the primary tumor, suggesting that those tumors originated from identical clones of the primary cHCC‐CCA tumors. Recurrent and co‐occurrent HCC tumors in the same patients with cHCC‐CCA had either common or different mutation patterns from the primary cHCC‐CCA tumors in each case. Conclusions: The study suggested that there were two subtypes of cHCC‐CCA, one involving TP53 mutations in the early stage of the carcinogenic process and the other not involving such mutations. The comparison of the variants between primary and recurrent tumors suggested that cHCC‐CCA was derived from an identical clone. [ABSTRACT FROM AUTHOR]

Published
2024
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37. Data from Expansion of Gastric Intestinal Metaplasia with Copy Number Aberrations Contributes to Field Cancerization

Author

Kumagai, Ken, primary, Shimizu, Takahiro, primary, Takai, Atsushi, primary, Kakiuchi, Nobuyuki, primary, Takeuchi, Yasuhide, primary, Hirano, Tomonori, primary, Takeda, Haruhiko, primary, Mizuguchi, Aya, primary, Teramura, Mari, primary, Ito, Takahiko, primary, Iguchi, Eriko, primary, Nikaido, Mitsuhiro, primary, Eso, Yuji, primary, Takahashi, Ken, primary, Ueda, Yoshihide, primary, Miyamoto, Shin'ichi, primary, Obama, Kazutaka, primary, Ogawa, Seishi, primary, Marusawa, Hiroyuki, primary, and Seno, Hiroshi, primary

Published
2023
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38. Supplementary Data from Genome-Wide RNAi Screen Identifies PMPCB as a Therapeutic Vulnerability in EpCAM+ Hepatocellular Carcinoma

Author

Takai, Atsushi, primary, Dang, Hien, primary, Oishi, Naoki, primary, Khatib, Subreen, primary, Martin, Sean P., primary, Dominguez, Dana A., primary, Luo, Ji, primary, Bagni, Rachel, primary, Wu, Xiaolin, primary, Powell, Katie, primary, Ye, Qing-Hai, primary, Jia, Hu-Liang, primary, Qin, Lun-Xiu, primary, Chen, Jinqiu, primary, Mitchell, Gary A., primary, Luo, Xiaoling, primary, Thorgeirsson, Snorri S., primary, and Wang, Xin Wei, primary

Published
2023
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39. Supplementary Data from Hes1 Is Essential in Proliferating Ductal Cell–Mediated Development of Intrahepatic Cholangiocarcinoma

Author

Matsumori, Tomoaki, primary, Kodama, Yuzo, primary, Takai, Atsushi, primary, Shiokawa, Masahiro, primary, Nishikawa, Yoshihiro, primary, Matsumoto, Tomonori, primary, Takeda, Haruhiko, primary, Marui, Saiko, primary, Okada, Hirokazu, primary, Hirano, Tomonori, primary, Kuwada, Takeshi, primary, Sogabe, Yuko, primary, Kakiuchi, Nobuyuki, primary, Tomono, Teruko, primary, Mima, Atsushi, primary, Morita, Toshihiro, primary, Ueda, Tatsuki, primary, Tsuda, Motoyuki, primary, Yamauchi, Yuki, primary, Kuriyama, Katsutoshi, primary, Sakuma, Yojiro, primary, Ota, Yuji, primary, Maruno, Takahisa, primary, Uza, Norimitsu, primary, Marusawa, Hiroyuki, primary, Kageyama, Ryoichiro, primary, Chiba, Tsutomu, primary, and Seno, Hiroshi, primary

Published
2023
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40. Table. S4 from Hes1 Is Essential in Proliferating Ductal Cell–Mediated Development of Intrahepatic Cholangiocarcinoma

Author

Matsumori, Tomoaki, primary, Kodama, Yuzo, primary, Takai, Atsushi, primary, Shiokawa, Masahiro, primary, Nishikawa, Yoshihiro, primary, Matsumoto, Tomonori, primary, Takeda, Haruhiko, primary, Marui, Saiko, primary, Okada, Hirokazu, primary, Hirano, Tomonori, primary, Kuwada, Takeshi, primary, Sogabe, Yuko, primary, Kakiuchi, Nobuyuki, primary, Tomono, Teruko, primary, Mima, Atsushi, primary, Morita, Toshihiro, primary, Ueda, Tatsuki, primary, Tsuda, Motoyuki, primary, Yamauchi, Yuki, primary, Kuriyama, Katsutoshi, primary, Sakuma, Yojiro, primary, Ota, Yuji, primary, Maruno, Takahisa, primary, Uza, Norimitsu, primary, Marusawa, Hiroyuki, primary, Kageyama, Ryoichiro, primary, Chiba, Tsutomu, primary, and Seno, Hiroshi, primary

Published
2023
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41. Supplementary Data from Expansion of Gastric Intestinal Metaplasia with Copy Number Aberrations Contributes to Field Cancerization

Author

Kumagai, Ken, primary, Shimizu, Takahiro, primary, Takai, Atsushi, primary, Kakiuchi, Nobuyuki, primary, Takeuchi, Yasuhide, primary, Hirano, Tomonori, primary, Takeda, Haruhiko, primary, Mizuguchi, Aya, primary, Teramura, Mari, primary, Ito, Takahiko, primary, Iguchi, Eriko, primary, Nikaido, Mitsuhiro, primary, Eso, Yuji, primary, Takahashi, Ken, primary, Ueda, Yoshihide, primary, Miyamoto, Shin'ichi, primary, Obama, Kazutaka, primary, Ogawa, Seishi, primary, Marusawa, Hiroyuki, primary, and Seno, Hiroshi, primary

Published
2023
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43. Data from Genome-Wide RNAi Screen Identifies PMPCB as a Therapeutic Vulnerability in EpCAM+ Hepatocellular Carcinoma

Author

Takai, Atsushi, primary, Dang, Hien, primary, Oishi, Naoki, primary, Khatib, Subreen, primary, Martin, Sean P., primary, Dominguez, Dana A., primary, Luo, Ji, primary, Bagni, Rachel, primary, Wu, Xiaolin, primary, Powell, Katie, primary, Ye, Qing-Hai, primary, Jia, Hu-Liang, primary, Qin, Lun-Xiu, primary, Chen, Jinqiu, primary, Mitchell, Gary A., primary, Luo, Xiaoling, primary, Thorgeirsson, Snorri S., primary, and Wang, Xin Wei, primary

Published
2023
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44. Data from Hes1 Is Essential in Proliferating Ductal Cell–Mediated Development of Intrahepatic Cholangiocarcinoma

Author

Matsumori, Tomoaki, primary, Kodama, Yuzo, primary, Takai, Atsushi, primary, Shiokawa, Masahiro, primary, Nishikawa, Yoshihiro, primary, Matsumoto, Tomonori, primary, Takeda, Haruhiko, primary, Marui, Saiko, primary, Okada, Hirokazu, primary, Hirano, Tomonori, primary, Kuwada, Takeshi, primary, Sogabe, Yuko, primary, Kakiuchi, Nobuyuki, primary, Tomono, Teruko, primary, Mima, Atsushi, primary, Morita, Toshihiro, primary, Ueda, Tatsuki, primary, Tsuda, Motoyuki, primary, Yamauchi, Yuki, primary, Kuriyama, Katsutoshi, primary, Sakuma, Yojiro, primary, Ota, Yuji, primary, Maruno, Takahisa, primary, Uza, Norimitsu, primary, Marusawa, Hiroyuki, primary, Kageyama, Ryoichiro, primary, Chiba, Tsutomu, primary, and Seno, Hiroshi, primary

Published
2023
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45. Fig. S4 from Hes1 Is Essential in Proliferating Ductal Cell–Mediated Development of Intrahepatic Cholangiocarcinoma

Author

Matsumori, Tomoaki, primary, Kodama, Yuzo, primary, Takai, Atsushi, primary, Shiokawa, Masahiro, primary, Nishikawa, Yoshihiro, primary, Matsumoto, Tomonori, primary, Takeda, Haruhiko, primary, Marui, Saiko, primary, Okada, Hirokazu, primary, Hirano, Tomonori, primary, Kuwada, Takeshi, primary, Sogabe, Yuko, primary, Kakiuchi, Nobuyuki, primary, Tomono, Teruko, primary, Mima, Atsushi, primary, Morita, Toshihiro, primary, Ueda, Tatsuki, primary, Tsuda, Motoyuki, primary, Yamauchi, Yuki, primary, Kuriyama, Katsutoshi, primary, Sakuma, Yojiro, primary, Ota, Yuji, primary, Maruno, Takahisa, primary, Uza, Norimitsu, primary, Marusawa, Hiroyuki, primary, Kageyama, Ryoichiro, primary, Chiba, Tsutomu, primary, and Seno, Hiroshi, primary

Published
2023
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48. Supplementary Table from Expansion of Gastric Intestinal Metaplasia with Copy Number Aberrations Contributes to Field Cancerization

Author

Kumagai, Ken, primary, Shimizu, Takahiro, primary, Takai, Atsushi, primary, Kakiuchi, Nobuyuki, primary, Takeuchi, Yasuhide, primary, Hirano, Tomonori, primary, Takeda, Haruhiko, primary, Mizuguchi, Aya, primary, Teramura, Mari, primary, Ito, Takahiko, primary, Iguchi, Eriko, primary, Nikaido, Mitsuhiro, primary, Eso, Yuji, primary, Takahashi, Ken, primary, Ueda, Yoshihide, primary, Miyamoto, Shin'ichi, primary, Obama, Kazutaka, primary, Ogawa, Seishi, primary, Marusawa, Hiroyuki, primary, and Seno, Hiroshi, primary

Published
2023
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