1. Heterogeneity of latent tuberculosis infection in a patient with lung cancer
- Author
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Fumihiro Yamaguchi, Takao Minakata, Sakiko Miura, Takashi Suzuki, and Hironori Sagara
- Subjects
Infectious and parasitic diseases ,RC109-216 ,Public aspects of medicine ,RA1-1270 - Abstract
Latent tuberculosis infection may become a source of tuberculosis dissemination, even in a subclinical case, which have no abnormalities in the pulmonary parenchyma based on imaging studies. In this case, we presented tiny granulomas beside squamous cell carcinoma in a woman positive for interferon-γ release assay (IGRA). She had no symptoms or abnormalities in the parenchyma, except for the primary lesion. Mycobacterium tuberculosis was cultured from the mediastinal lymph nodes in concurrence with [18F] fluoro-deoxy glucose uptake. The findings of the present study stress the need for careful attention to the development of tuberculosis in case of a positive IGRA. Keywords: Mycobacterium tuberculosis, Latent tuberculosis infection, Interferon-γ release assay, [18F] fluoro-deoxy glucose positron emission tomography combined with computed tomography, Squamous cell lung carcinoma
- Published
- 2020
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