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Your search keyword '"Takayama, Hiroomi"' showing total 22 results
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22 results on '"Takayama, Hiroomi"'

7. Control of inferior vena cava injury during laparoscopic surgery using a double balloon-equipped central venous catheter: proof of concept in a live porcine model

Author

Iwashita, Yukio, Uchida, Hiroki, Takayama, Hiroomi, Ichimanda, Michihiro, Taniguchi, Katsuya, Kiguchi, Hideki, Sakaguchi, Tetsumi, Fujishima, Hajime, Saga, Kunihiro, Tada, Kazuhiro, Hara, Takao, Watanabe, Kiminori, Hirashita, Teijiro, Endo, Yuichi, Ohta, Masayuki, and Inomata, Masafumi

Published
2018
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11. Benefits of neoadjuvant chemotherapy with gemcitabine plus S-1 for resectable pancreatic ductal adenocarcinoma.

Author

Hirashita, Teijiro, Tada, Kazuhiro, Nagasawa, Yuiko, Orimoto, Hiroki, Kawamura, Masahiro, Fujinaga, Atsuro, Takayama, Hiroomi, Kawano, Yoko, Masuda, Takashi, Endo, Yuichi, and Inomata, Masafumi

Abstract

Currently, neoadjuvant chemotherapy (NAC) is usually performed even for resectable pancreatic ductal adenocarcinoma (rPDAC). The present study investigated the benefits of NAC with gemcitabine plus S-1 for rPDAC. The medical records of 170 patients diagnosed as having rPDAC based on preoperative imaging were reviewed retrospectively. Clinicopathological factors in the NAC group were compared with those in the upfront surgery (UpS) group. NAC was administered to 30 of the 170 patients. The period from first visit to treatment in the NAC group was shorter than that in the UpS group (P<0.001). Staging laparoscopy detected occult distant metastases in 12 of the 170 patients (7%), of whom all 12 were in the UpS group. All patients in the NAC group underwent surgical resection (P=0.028). Among the 158 patients who underwent pancreatectomy, the NAC group showed rapid induction of the treatment, non-inferior operative outcomes and a higher R0 rate compared with the UpS group. Rates of early recurrence (within 6 months) after surgery were 10% (3/30) in the NAC group and 29% (37/128) in the UpS group (P=0.021). NAC for rPDAC is beneficial in terms of rapid induction of the treatment, fewer occult metastases, and lower rate of early recurrence. [ABSTRACT FROM AUTHOR]

Published
2025
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12. Secondary Unconjugated Bile Acids Induce Hepatic Stellate Cell Activation

Author

Saga, Kunihiro, primary, Iwashita, Yukio, additional, Hidano, Shinya, additional, Aso, Yuiko, additional, Isaka, Kenji, additional, Kido, Yasutoshi, additional, Tada, Kazuhiro, additional, Takayama, Hiroomi, additional, Masuda, Takashi, additional, Hirashita, Teijiro, additional, Endo, Yuichi, additional, Ohta, Masayuki, additional, Kobayashi, Takashi, additional, and Inomata, Masafumi, additional

Published
2018
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16. Control of inferior vena cava injury during laparoscopic surgery using a double balloon-equipped central venous catheter: proof of concept in a live porcine model

Author

Iwashita, Yukio, primary, Uchida, Hiroki, additional, Takayama, Hiroomi, additional, Ichimanda, Michihiro, additional, Taniguchi, Katsuya, additional, Kiguchi, Hideki, additional, Sakaguchi, Tetsumi, additional, Fujishima, Hajime, additional, Saga, Kunihiro, additional, Tada, Kazuhiro, additional, Hara, Takao, additional, Watanabe, Kiminori, additional, Hirashita, Teijiro, additional, Endo, Yuichi, additional, Ohta, Masayuki, additional, and Inomata, Masafumi, additional

Published
2017
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18. Long-term outcomes of laparoscopic versus open splenectomy for immune thrombocytopenia.

Author

Tada, Kazuhiro, Ohta, Masayuki, Saga, Kunihiro, Takayama, Hiroomi, Hirashita, Teijiro, Endo, Yuichi, Uchida, Hiroki, Iwashita, Yukio, and Inomata, Masafumi

Subjects
IDIOPATHIC thrombocytopenic purpura, SPLENECTOMY, LAPAROSCOPY, HEALTH outcome assessment, THERAPEUTICS
Abstract

Purpose: Splenectomy is the standard therapy for medically refractory immune thrombocytopenia (ITP). Laparoscopic splenectomy (LS) has gained wide acceptance; however, the long-term outcomes of LS versus open splenectomy (OS) for patients with ITP remain unclear. Methods: We analyzed, retrospectively, 32 patients who underwent splenectomy, as LS in 22 and OS in 10, for refractory ITP at our institute. Data were evaluated based on the American Society of Hematology 2011 evidence-based practice guidelines for ITP. Results: Although the operation time was significantly longer in the LS group ( p < 0.01), LS was associated with less blood loss ( p < 0.01), infrequent blood transfusion during surgery ( p < 0.01), quicker resumption of oral intake ( p < 0.01), and shorter hospital stay ( p < 0.01) than OS. Positive responses, including complete and partial remission, were achieved in 90% of the OS group patients and 77% of the LS group patients. The mean follow-up periods were 183 and 92 months, respectively. Relapse-free survival rates, 15 years after the operation were 63% in the OS group and 94% in the LS group. Conclusions: LS can provide better short-term results and comparable long-term results to those of OS for ITP. [ABSTRACT FROM AUTHOR]

Published
2018
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