Search

Your search keyword '"Takeshi Okuda"' showing total 251 results
Start Over Author "Takeshi Okuda"
251 results on '"Takeshi Okuda"'

1. Spatial Cognition Ability in Surgeons Performing Endoscopic Endonasal Transsphenoidal Surgery

Author

Juli YAMASHITA, Takeshi OKUDA, Takayuki TASAKI, and Jun TAKAHASHI

Subjects
endoscopic endonasal transsphenoidal surgery, training, spatial orientation test, psychomotor skill, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

Endoscopic surgery, including endoscopic endonasal transsphenoidal surgery (ETSS), requires special psychomotor skills from surgeons. The learning curve in the acquisition of psychomotor skills varies among individuals, and studies about laparoscopy indicate that the difference can be predicted using spatial ability tests. We examined the association between the results of such tests and the learning curve in ETSS to determine the need for a personalized curriculum for ETSS skill training. A total of 30 fifth-year medical students from Kindai University School of Medicine (17 men, 13 women; mean age, 26 years) without ETSS experience completed the spatial orientation test (SOT) for the measurement of spatial visualization ability. They performed the dural incision task (DIT) twice on an ETSS training model for surgical psychomotor skill evaluation. The SOT scores (angle errors) exhibited substantial individual differences in spatial visualization ability, whereas the DIT scores significantly improved in the second trial (Wilcoxon signed-rank test, P = 0.0035). However, no significant difference was observed in the DIT scores between the smaller error and larger error groups of the SOT. The results indicated that two DIT trials were sufficient to acquire psychomotor skills for the DIT as the endoscope was almost fixed and learning only one viewpoint and line of sight combination was adequate. In conclusion, a personalized ETSS training program based on the trainee's spatial ability is not necessary for the DIT. Further research is warranted to determine the effect of spatial ability on more complex tasks, such as suturing in cranial base repair.

Published
2024
Full Text
View/download PDF

2. Immersive Virtual Reality Reminiscence Reduces Anxiety in the Oldest-Old Without Causing Serious Side Effects: A Single-Center, Pilot, and Randomized Crossover Study

Author

Kazuyuki Niki, Megumi Yahara, Michiya Inagaki, Nana Takahashi, Akira Watanabe, Takeshi Okuda, Mikiko Ueda, Daisuke Iwai, Kosuke Sato, and Toshinori Ito

Subjects
virtual reality, reminiscence, anxiety, satisfaction, late elderly, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

Background: Dementia is one the major problems of aging societies, and, novel and effective non-drug therapies are required as interventions in the oldest-old to prevent cognitive decline.Objective: This study aims to examine the efficacy and safety of reminiscence using immersive virtual reality (iVR reminiscence) focusing on anxiety that often appears with cognitive decline. The secondary objective is to reveal the preference for VR image types for reminiscence: live-action (LA) or computer graphics (CG).Methods: This was a pilot, open-label, and randomized crossover study which was conducted on January 2020 at a single nursing home. The subjects were randomly divided into two groups (A or B) in equal numbers, and they alternately viewed two types of VR images (LA and CG) themed on the mid- to late Showa era (A.D. 1955–1980) in Japan. In group A, the CG images were viewed first, and then the LA images were viewed (CG→ LA). In group B, the images were viewed in the opposite order (LA→ CG). Before VR viewing, subjects responded to Mini-Mental State Examination (MMSE) Japanese version and State-Trait Anxiety Inventory (STAI) Japanese version. After viewing the first and second VR, subjects responded to STAI and the numerical rating scale (NRS) for satisfaction and side effects (nausea, dizziness, headache, and tiredness).Results: Ten subjects participated in this study. The values of analyses are presented in the mean (SD). The age was 87.1 years (4.2), and the MMSE was 28.5 (1.8). The total STAI score before VR viewing was 36.1 (7.2), but it significantly decreased to 26.8 (4.9) after the first VR viewing (P = 0.0010), and further decreased to 23.4 (2.8) after the second VR viewing (P < 0.001). The NRS score for satisfaction tended to be higher after viewing LA in group A (CG→ LA) (CG vs. LA; 7.0 (2.3) vs. 8.6 (1.5), P = 0.0993), while in group B (LA→ CG), the score after CG was slightly lower than that after LA. There were no serious side effects.Conclusions: This study suggests that iVR reminiscence can reduce anxiety in the oldest-old without causing serious side effects. Furthermore, the impacts might be better with LA images.

Published
2021
Full Text
View/download PDF

3. A nationwide multi-institutional retrospective study to identify prognostic factors and develop a graded prognostic assessment system for patients with brain metastases from uterine corpus and cervical cancer

Author

Nakamasa Hayashi, Hideaki Takahashi, Yuzo Hasegawa, Fumi Higuchi, Masamichi Takahashi, Keishi Makino, Masatoshi Takagaki, Jiro Akimoto, Takeshi Okuda, Yoshiko Okita, Koichi Mitsuya, Yasuyuki Hirashima, Yoshitaka Narita, Yoko Nakasu, and On Behalf of the Committee of Brain Tumor Registry of Japan Supported by the Japan Neurosurgical Society

Subjects
Brain metastasis, Graded prognostic assessment, Radiation, Surgery, Uterine cervical cancer, Uterine corpus cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Background The prevalence of brain metastases (BM) from uterine cancer has recently increased because of the improvement of overall survival (OS) of patients with uterine cancer due to its early detection and improved local control as a result of new effective treatments. However, little information is available regarding their clinical characteristics and prognosis, because oncologists have encountered BM from uterine cancer on rare occasions. Methods Records from 81 patients with uterine BM were collected from 10 institutes in Japan. These were used in a multi-institutional study to identify prognostic factors and develop a graded prognostic assessment (GPA) for patients with BM from uterine cancer. Results Median OS after the development of BM was 7 months (95% confidence interval, 4 to 10 months). Multivariate analysis revealed that there were survival differences according to the existence of extracranial metastases and number of BM. In the present uterine-GPA, a score of 0 was assigned to those patients with ≥5 BM and extracranial metastasis, a score of 2 was assigned to those patients with one to four BM or without extracranial metastasis, and a score of 4 was assigned to those patients with one to four BM and without extracranial metastasis. The median OS for patients with a uterine-GPA scores of 0, 2, and 4 was 3, 7, and 22 months, respectively. A survival analysis confirmed the presence of statistically significant differences between these groups (p

Published
2017
Full Text
View/download PDF

4. Epstein–Barr Virus-Induced Post-Transplant Lymphoproliferative Disorder of the Central Nervous System Successfully Treated with Chemo-Immunotherapy

Author

Hiroaki Inoue, Shinya Rai, Hirokazu Tanaka, J. Luis Espinoza, Maiko Komori-Inoue, Hiroaki Kakutani, Shuji Minamoto, Takahiro Kumode, Shoko Nakayama, Yasuhiro Taniguchi, Yasuyoshi Morita, Takeshi Okuda, Yoichi Tatsumi, Takashi Ashida, and Itaru Matsumura

Subjects
aplastic anemia, EBV, lymphoproliferative disorder, immunosuppressive therapy, transplant complications, Microbiology, QR1-502
Abstract

Aplastic anemia is a rare blood disease characterized by the destruction of the hematopoietic stem cells (HSC) in the bone marrow that, in the majority of cases, is caused by an autoimmune reaction. Patients with aplastic anemia are treated with immunosuppressive drugs and some of them, especially younger individuals with a donor available, can be successfully treated with hematopoietic stem cell transplantation (HSCT). We report here a rare case of post-transplant lymphoproliferative disorder (PTLD) associated with Epstein–Barr virus (EBV) reactivation in a 30-year-old female patient who underwent allogeneic HSCT for severe aplastic anemia. The PTLD, which was diagnosed 230 days after transplantation, was localized exclusively in the central nervous system (specifically in the choroid plexus) and manifested with obvious signs of intracranial hypertension. After receiving three cycles of high dose methotrexate (HD-MTX) combined with rituximab, the patient achieved a complete clinical recovery with normalization of blood cell counts, no evidence of EBV reactivation, and no associated neurotoxicity.

Published
2020
Full Text
View/download PDF

5. Data Delivery Method Based on Neighbor Nodes’ Information in a Mobile Ad Hoc Network

Author

Shigeru Kashihara, Takuma Hayashi, Yuzo Taenaka, Takeshi Okuda, and Suguru Yamaguchi

Subjects
Technology, Medicine, Science
Abstract

This paper proposes a data delivery method based on neighbor nodes’ information to achieve reliable communication in a mobile ad hoc network (MANET). In a MANET, it is difficult to deliver data reliably due to instabilities in network topology and wireless network condition which result from node movement. To overcome such unstable communication, opportunistic routing and network coding schemes have lately attracted considerable attention. Although an existing method that employs such schemes, MAC-independent opportunistic routing and encoding (MORE), Chachulski et al. (2007), improves the efficiency of data delivery in an unstable wireless mesh network, it does not address node movement. To efficiently deliver data in a MANET, the method proposed in this paper thus first employs the same opportunistic routing and network coding used in MORE and also uses the location information and transmission probabilities of neighbor nodes to adapt to changeable network topology and wireless network condition. The simulation experiments showed that the proposed method can achieve efficient data delivery with low network load when the movement speed is relatively slow.

Published
2014
Full Text
View/download PDF

10. Experience With Tirabrutinib in the Treatment of Primary Central Nervous System Lymphoma that Is Difficult to Treat With Standard Treatment

Author

Hiromasa, Yoshioka, Takeshi, Okuda, Takayuki, Nakao, Mitsugu, Fujita, and Jun C, Takahashi

Subjects
Central Nervous System, Male, Cancer Research, Brain Neoplasms, Lymphoma, Non-Hodgkin, Imidazoles, General Medicine, Central Nervous System Neoplasms, Methotrexate, Pyrimidines, Oncology, Antineoplastic Combined Chemotherapy Protocols, Humans, Female, Cranial Irradiation, Aged, Retrospective Studies
Abstract

Standard treatment options for primary central nervous system lymphoma (PCNSL) include high-dose methotrexate (HD-MTX)-based drug therapy and whole-brain radiation therapy. However, there are many cases in which these standard treatment options are not tolerated for various reasons. In the present study, five cases of refractory/relapsed PCNSL that are difficult to treat with standard treatment were successfully treated by tirabrutinib.A total of 5 patients (4 women, 1 man) with refractory (n=3) and relapsed (n=2) PCNSL were included. The patients had a median age of 76 years and a median Karnofsky performance status (KPS) of 40. The reasons why standard treatment cannot be given to these patients are the low KPS, renal dysfunction, and resistance to HD-MTX. Administration of a drug via the oral route was challenging in three patients; thus, these patients were administered tirabrutinib in suspension through a nasogastric tube.Imaging findings showed that the patients achieved a 100% response rate to tirabrutinib, with a median survival of 8 months. As symptoms improved, 2 of the 3 patients who were initially administered tirabrutinib via a nasogastric tube were able to receive the drug via the oral route. Three patients developed adverse reactions; however, treatment was not interrupted because they were manageable.Tirabrutinib was effective in the treatment of patients who were unable to receive standard treatment options. Tirabrutinib may be considered one of the novel treatment strategies that could improve the prognosis of PCNSL patients in the future.

Published
2022
Full Text
View/download PDF

28. Remote Reminiscence Using Immersive Virtual Reality May Be Efficacious for Reducing Anxiety in Patients with Mild Cognitive Impairment Even in COVID-19 Pandemic: A Case Report

Author

Yasuo Naito, Mikiko Ueda, Hiroyuki Tanaka, Toshinori Ito, Ryouhei Ishii, Takeshi Okuda, Keita Ueno, Megumi Yahara, Kazuyuki Niki, and Mio Okamoto

Subjects
Male, Imagery, Psychotherapy, Psychotherapist, Pharmaceutical Science, Interpersonal communication, Anxiety, Patient satisfaction, Reminiscence, Pandemic, medicine, Humans, Dementia, Cognitive Dysfunction, Session (computer science), Cognitive decline, Aged, 80 and over, Pharmacology, Virtual Reality, General Medicine, medicine.disease, Mobile Applications, Telemedicine, Nursing Homes, Treatment Outcome, Patient Satisfaction, Female, medicine.symptom, Psychology
Abstract

To prevent cognitive decline, non-pharmacological therapies such as reminiscence for mild cognitive impairment (MCI) are required, however, the use of nursing homes was limited due to coronavirus disease 2019 (COVID-19). Therefore, the demand for remote-care is increasing. We hypothesized that immersive virtual reality (iVR) could be used more effectively than conventional reminiscence for anxiety. We first examined the effectiveness and safety of reminiscence using iVR (iVR reminiscence session) in patients with MCI. After COVID-19 imposed restriction on visiting nursing homes, we conducted online iVR reminiscence session (remote iVR reminiscence session) and compared its effectiveness with that of interpersonal iVR reminiscence session (face-to-face iVR reminiscence session). The results of two elderly with MCI suggested that iVR reminiscence could reduce anxiety and the burden of care without serious side effects. The effects of remote iVR reminiscence might be almost as effective as those of face-to-face one.

Published
2021
Full Text
View/download PDF

31. High 11 C-Methionine Uptake in a Parasellar Inflammatory Pseudotumor

Author

Hayato Kaida, Takeshi Okuda, Kohei Hanaoka, and Kazunari Ishii

Subjects
Adult, Male, Optic Nerve Glioma, Young Adult, Methionine, Brain Neoplasms, Positron-Emission Tomography, Humans, Radiology, Nuclear Medicine and imaging, General Medicine, Magnetic Resonance Imaging, Granuloma, Plasma Cell, Racemethionine
Abstract

A 20-year-old man had left visual impairment and homonymous hemianopsia. MRI findings suggested enlargement of an optic glioma, because optic glioma was indicated by MRI 14 years earlier without a definite pathological diagnosis. 11 C-methionine (MET) PET showed high uptake in the tumor in the parasellar region. Transnasal endoscopic biopsy was performed, and an inflammatory pseudotumor (IPT) was diagnosed based on histopathological findings. High MET uptake in a parasellar IPT has apparently not been previously reported. Clinicians should be aware of the possibility of high MET uptake in IPT, because this image could provide an interpretation pitfall.

Published
2022

32. ПОИСК НЕЙТРИНО УЛЬТРАВЫСОКИХ ЭНЕРГИЙ ПО ДАННЫМ НАЗЕМНОЙ РЕШЕТКИ ЭКСПЕРИМЕНТА TELESCOPE ARRAY

Author

Taka Tomida, J. Remington, Kenta Yashiro, Yasunori Saito, M. Abe, O. Kalashev, Jonathan Smith, Takeshi Okuda, Igor Tkachev, N. Inoue, M. Ohnishi, Federico R. Urban, Yuichiro Tameda, H. Oda, Akimichi Taketa, T. Suzawa, Naoaki Hayashida, Shingo Kawana, Yasuhiro H. Takahashi, John N. Matthews, Isaac Myers, Vladim Kuzmin, William Hanlon, Elliott Barcikowski, Seok Ho Jeong, K. Nagasawa, B. G. Cheon, Hidemi Ito, Fumiya Shibata, Zach Zundel, J. Yang, S. Kitamura, Dmitri Ivanov, Keijiro Mukai, R. Sahara, John Belz, Y. J. Kwon, Hideyuki Ohoka, Fumio Kakimoto, Toshiyuki Nonaka, Toshitsugu Fujii, Daisuke Ikeda, R. Ishimori, Yuta Tanoue, D. R. Bergman, S. R. Stratton, G. Furlich, Takaaki Ishii, Tiffany Wong, Hideki Tanaka, K. Kadota, Inkyu Park, Motoki Hayashi, Hisono Tokuno, T. K. Sako, J. P. Lundquist, D. C. Rodriguez, Ben Stokes, Toru Nakamura, K. Yamazaki, Hongsu Kim, S. B. Thomas, Masahiro Fukushima, S. Kawakami, K. Hibino, Pierre Sokolsky, Ryo Nakamura, K. H. Lee, Jihee Kim, T.-A. Shibata, Eiji Kido, M. V. Kuznetsov, Kazuhiro Machida, Hiroshi Yamaoka, Keitaro Fujita, M. Takeda, Shigehiro Nagataki, Yana Zhezher, Y. Uchihori, Kei Nakai, Kohei Yada, Gordon Thomson, Tom Stroman, Robert Cady, Kazuo Saito, Charlie Jui, BayarJon Paul Lubsandorzhiev, Hiroyuki Sagawa, Mayuko Minamino, Michiyuki Chikawa, K. Honda, Yasunori Kitamura, Grigory Rubtsov, Masaaki Tanaka, Kalen Martens, M. Takita, H. Yoshii, Bokkyun Shin, Koichi Sekino, Kiyoshi Tanaka, Maxim Pshirkov, Jyunsei Chiba, P. Tinyakov, Dongsu Ryu, Y. Omura, Mai Takamura, Y. Takagi, Samuel Blake, Shoichi Ogio, Priti Shah, Ryuji Takeishi, J. Ogura, M. Allen, K. Kasahara, Shoichi Kishigami, Akitoshi Oshima, Y. Tsunesada, Hideaki Shimodaira, Hyoming Jeong, Masaomi Ono, K. Tsutsumi, Rasha Abbasi, Tareq Abu-Zayyad, L. M. Scott, Y. Hayashi, K. Kawata, M. Yamamoto, Nobuyuki Sakurai, Ryota Onogi, J. H. Kim, A. Di Matteo, Ryota Fujiwara, R. Mayta, Heungsu Shin, Naoto Sakaki, Shigeharu Udo, R. Azuma, H. Kawai, T. Seki, T. Matsuyama, S. Ozawa, and Sergey Troitsky

Subjects
General Physics and Astronomy
Published
2020
Full Text
View/download PDF

35. Study on the cosmic ray intensity variation using scintillation counters for air shower observation

Author

Ryuji Takeishi, Daiki Shinto, Priti Shah, Michiyuki Chikawa, Ryo Nakamura, Shingo Kawana, Rasha Abbasi, Masahiro Takeda, Ken Honda, Takashi Sako, M. Ohnishi, Taichi Inadomi, Kinya Hibino, William Hanlon, Sergey Troitsky, Fumiya Shibata, Saori Kasami, G. Furlich, Takaaki Ishii, Aoi Iwasaki, Taka Tomida, Jyunsei Chiba, Dongsu Ryu, Fugo Yoshida, J. Remington, Ben Stokes, Min Hyo Kim, Koki Sato, Zach Zundel, Matt Potts, Kenta Yashiro, Hirokazu Iwakura, Kengo Sano, Federico R. Urban, Nobuyuki Sakurai, Y. Takagi, D. C. Rodriguez, HangBae Kim, Vladim Kuzmin, Hideki Tanaka, Shinnosuke Kurisu, Keitaro Fujita, Shigeharu Udo, Hisono Tokuno, Hideaki Shimodaira, Hyoming Jeong, Takeshi Okuda, Igor Tkachev, Naohiro Sone, Naoaki Hayashida, Tatsunobu Shibata, H. Oda, Ivan Kharuk, Ryuhei Arimura, S. Kawakami, Stanton Thomas, Akitoshi Oshima, Ryota Fujiwara, Toshiyuki Nonaka, Ryo Higuchi, Shunsuke Ozawa, Yuta Tanoue, Ricardo Gonzalez, Yoshiki Tsunesada, Daisuke Ikeda, Naoto Sakaki, Katsuaki Kasahara, Pierre Sokolsky, Yuya Oku, Arata Nakazawa, Katsumasa Kawata, Charlie Jui, Motoki Hayashi, Shigehiro Nagataki, Oleg Kalashev, Tiffany Wong, Samuel Blake, Hirotaka Ito, Shoichi Ogio, Yana Zhezher, Hiroyuki Sagawa, Kei Nakai, BayarJon Paul Lubsandorzhiev, Sang Woo Kim, Masaki Fukushima, Fumio Kakimoto, M. Yamamoto, Yuichiro Tameda, Heungsu Shin, Mayuko Minamino, K. Yamazaki, Kozo Fujisue, Jeremy Smith, Tareq Abu-Zayyad, John Matthews, Tsubasa Yoshioka, Koichi Tanaka, J. Yang, Tomoyuki Nakamura, Yukio Uchihori, Toru Nakamura, Koichi Sekino, Jon Paul Lundquist, Kenichi Kadota, Youngjoon Kwon, John Belz, Akimichi Taketa, Eiji Nishio, P. Tinyakov, Il Hung Park, Masato Takita, Ryota Fukushima, Ryota Onogi, J. H. Kim, Mikhail Kuznetsov, Maxim Pshirkov, Y. Takahashi, Mai Takamura, Yuto Arai, Isaac Myers, Hideyuki Kawai, Yuma Shibasaki, R. Mayta, Douglas Bergman, Grigory Rubtsov, Ryosuke Tsuda, Soomin Jeong, R. Sahara, T. Seki, Naoya Inoue, Yasunori Saito, Hiroyuki Matsumiya, Takafumi Uehama, Eiji Kido, Kazuhiro Machida, Telescope Array, Shoichi Kishigami, Masaomi Ono, Norimichi Shibata, Y. Omura, Monica Allen, Bokkyun Shin, ByongGu Cheon, Elliott Barcikowski, Dmitri Ivanov, Keijiro Mukai, Hideyuki Ohoka, Yusuke Kimura, Toshio Matsuyama, Manobu Tanaka, K. H. Lee, Jihee Kim, Gordon Thomson, Tom Stroman, Robert Cady, Toshihiro Fujii, Yuto Kubota, Y. Nakamura, and Kohei Yada

Subjects
Physics, Air shower, Scintillation counter, Cosmic ray, Astrophysics, Variation (astronomy), Intensity (heat transfer)
Published
2021
Full Text
View/download PDF

36. Anisotropy search in the Ultra High Energy Cosmic Ray Spectrum in the Northern Hemisphere using latest data obtained with Telescope Array surface detector

Author

Grigory Rubtsov, John Matthews, Norimichi Shibata, Y. Omura, J. Yang, Fumiya Shibata, Shingo Kawana, M. Ohnishi, Taichi Inadomi, Matt Potts, William Hanlon, Monica Allen, Bokkyun Shin, Fugo Yoshida, Yuma Shibasaki, ByongGu Cheon, Ben Stokes, Douglas Bergman, Jyunsei Chiba, Dongsu Ryu, Toshihiro Fujii, Koki Sato, Yasunori Saito, M. Yamamoto, Hirokazu Iwakura, Y. Takagi, Ryuhei Arimura, Hideyuki Ohoka, Yuto Kubota, Federico R. Urban, Nobuyuki Sakurai, Kengo Sano, Mikhail Kuznetsov, Heungsu Shin, Ivan Kharuk, Yukio Uchihori, Keitaro Fujita, K. H. Lee, Jihee Kim, Yoshiki Tsunesada, Daisuke Ikeda, Hirotaka Ito, Sergey Troitsky, Yuto Arai, Ryota Onogi, J. H. Kim, Maxim Pshirkov, Takeshi Okuda, Y. Nakamura, Kohei Yada, Charlie Jui, BayarJon Paul Lubsandorzhiev, Mayuko Minamino, Hiroyuki Matsumiya, Igor Tkachev, R. Mayta, Hideki Tanaka, Naohiro Sone, Ryosuke Tsuda, Tiffany Wong, Taka Tomida, J. Remington, Masaki Fukushima, Takafumi Uehama, Aoi Iwasaki, Daiki Shinto, Hideaki Shimodaira, Hyoming Jeong, Shoichi Kishigami, Soomin Jeong, Shigeharu Udo, Eiji Kido, Hiroyuki Sagawa, Takashi Sako, Ryo Higuchi, Hisono Tokuno, H. Oda, Gordon Thomson, Tom Stroman, Priti Shah, Ryo Nakamura, Robert Cady, Kazuhiro Machida, Masahiro Takeda, Pierre Sokolsky, Naoaki Hayashida, Ken Honda, Tatsunobu Shibata, T. Seki, G. Furlich, Takaaki Ishii, R. Sahara, Fumio Kakimoto, Naoya Inoue, Akitoshi Oshima, Vladim Kuzmin, Ryuji Takeishi, Ryota Fukushima, Shigehiro Nagataki, Shunsuke Ozawa, K. Yamazaki, Masaomi Ono, Elliott Barcikowski, Toshiyuki Nonaka, Saori Kasami, Tareq Abu-Zayyad, Zach Zundel, Yana Zhezher, Kenta Yashiro, Dmitri Ivanov, D. C. Rodriguez, Ricardo Gonzalez, Samuel Blake, Sang Woo Kim, Kinya Hibino, Shoichi Ogio, Keijiro Mukai, HangBae Kim, Yusuke Kimura, Rasha Abbasi, Koichi Tanaka, Yuya Oku, Michiyuki Chikawa, Jon Paul Lundquist, Katsuaki Kasahara, Stanton Thomas, Katsumasa Kawata, Oleg Kalashev, Yuichiro Tameda, Tomoyuki Nakamura, Tsubasa Yoshioka, Arata Nakazawa, Masato Takita, Toru Nakamura, Telescope Array, Min Hyo Kim, Toshio Matsuyama, Kei Nakai, Ryota Fujiwara, Kenichi Kadota, Manobu Tanaka, Il Hung Park, Naoto Sakaki, S. Kawakami, Akimichi Taketa, Eiji Nishio, Hideyuki Kawai, Shinnosuke Kurisu, Jeremy Smith, Isaac Myers, Youngjoon Kwon, John Belz, Koichi Sekino, P. Tinyakov, Y. Takahashi, Mai Takamura, Yuta Tanoue, Motoki Hayashi, and Kozo Fujisue

Subjects
Surface (mathematics), Telescope, Physics, law, Detector, Northern Hemisphere, Astrophysics, Ultra-high-energy cosmic ray, Anisotropy, law.invention
Published
2021
Full Text
View/download PDF

37. The measurements of the cosmic ray energy spectrum and the depth of maximum shower development of Telescope Array Hybrid trigger events

Author

Katsuaki Kasahara, Shinnosuke Kurisu, Katsumasa Kawata, Shingo Kawana, William Hanlon, Tsubasa Yoshioka, R. Sahara, Hideaki Shimodaira, Hyoming Jeong, Ryo Higuchi, Norimichi Shibata, Monica Allen, Bokkyun Shin, Jeremy Smith, Y. Omura, Vladim Kuzmin, G. Furlich, Takaaki Ishii, Akimichi Taketa, Toshio Matsuyama, Eiji Nishio, ByongGu Cheon, K. Yamazaki, Tareq Abu-Zayyad, Toshiyuki Nonaka, Hideyuki Ohoka, D. C. Rodriguez, Fumiya Shibata, Hiroyuki Matsumiya, Fugo Yoshida, HangBae Kim, Hiroyuki Sagawa, Ricardo Gonzalez, Pierre Sokolsky, Tatsunobu Shibata, Hideyuki Kawai, Takafumi Uehama, Manobu Tanaka, Rasha Abbasi, Takeshi Okuda, Youngjoon Kwon, John Belz, Yuma Shibasaki, Shigehiro Nagataki, Matt Potts, Yana Zhezher, Mikhail Kuznetsov, Akitoshi Oshima, Igor Tkachev, Sang Woo Kim, Eiji Kido, Koichi Tanaka, K. H. Lee, Jihee Kim, Kazuhiro Machida, Isaac Myers, Naohiro Sone, Shunsuke Ozawa, Hideki Tanaka, Heungsu Shin, Douglas Bergman, Gordon Thomson, Ryo Nakamura, Jon Paul Lundquist, Tom Stroman, Robert Cady, Yuta Tanoue, Ben Stokes, H. Oda, Grigory Rubtsov, Tomoyuki Nakamura, Yasunori Saito, Yuto Arai, Motoki Hayashi, Ryota Fujiwara, Federico R. Urban, Nobuyuki Sakurai, Ryosuke Tsuda, Hirotaka Ito, Hisono Tokuno, Elliott Barcikowski, Charlie Jui, Soomin Jeong, Naoto Sakaki, Kozo Fujisue, BayarJon Paul Lubsandorzhiev, Mayuko Minamino, Yuya Oku, Oleg Kalashev, Dmitri Ivanov, Fumio Kakimoto, Arata Nakazawa, Kenta Yashiro, Kei Nakai, T. Seki, Naoya Inoue, Keijiro Mukai, Min Hyo Kim, Yusuke Kimura, S. Kawakami, Stanton Thomas, M. Ohnishi, Taichi Inadomi, Koki Sato, Sergey Troitsky, Kengo Sano, Aoi Iwasaki, Toshihiro Fujii, Michiyuki Chikawa, Toru Nakamura, Taka Tomida, J. Remington, Kenichi Kadota, Yuto Kubota, Il Hung Park, Saori Kasami, Y. Nakamura, Kohei Yada, Koichi Sekino, Naoaki Hayashida, P. Tinyakov, Ryuji Takeishi, Ryuhei Arimura, Yoshiki Tsunesada, Daisuke Ikeda, Tiffany Wong, Masaki Fukushima, Takashi Sako, Zach Zundel, John Matthews, J. Yang, Daiki Shinto, Priti Shah, Jyunsei Chiba, Dongsu Ryu, Masahiro Takeda, Ken Honda, Hirokazu Iwakura, Y. Takagi, Shigeharu Udo, Keitaro Fujita, Ryota Fukushima, Ivan Kharuk, M. Yamamoto, Yukio Uchihori, Ryota Onogi, J. H. Kim, R. Mayta, Kinya Hibino, Yuichiro Tameda, Masato Takita, Shoichi Kishigami, Y. Takahashi, Mai Takamura, Masaomi Ono, Telescope Array, Samuel Blake, Shoichi Ogio, and Maxim Pshirkov

Subjects
Telescope, Physics, Shower, law, Energy spectrum, Astronomy, Cosmic ray, law.invention
Published
2021
Full Text
View/download PDF

38. Cosmic ray energy spectrum in the 2nd knee region measured by the TALE-SD array

Author

Taka Tomida, J. Remington, G. Furlich, Takaaki Ishii, D. C. Rodriguez, Stanton Thomas, Hideki Tanaka, HangBae Kim, Fumiya Shibata, Naoaki Hayashida, Hiroyuki Matsumiya, ByongGu Cheon, Fugo Yoshida, Michiyuki Chikawa, Pierre Sokolsky, Shigehiro Nagataki, Yana Zhezher, Isaac Myers, Maxim Pshirkov, Sang Woo Kim, Matt Potts, Telescope Array, Hisono Tokuno, Ryuhei Arimura, Vladim Kuzmin, Daiki Shinto, Toru Nakamura, Takafumi Uehama, Koichi Sekino, Tomoyuki Nakamura, Takeshi Okuda, P. Tinyakov, Heungsu Shin, R. Sahara, Aoi Iwasaki, Yoshiki Tsunesada, Kenichi Kadota, Priti Shah, Daisuke Ikeda, Igor Tkachev, Il Hung Park, Toshiyuki Nonaka, Hideyuki Ohoka, Shoichi Kishigami, Rasha Abbasi, Masahiro Takeda, Naohiro Sone, Arata Nakazawa, Y. Takahashi, Mai Takamura, Ricardo Gonzalez, Tiffany Wong, Eiji Kido, Kei Nakai, Ben Stokes, Kazuhiro Machida, Masaki Fukushima, Ken Honda, H. Oda, Katsuaki Kasahara, Masaomi Ono, Yuto Arai, Toshihiro Fujii, Jyunsei Chiba, Katsumasa Kawata, Takashi Sako, Charlie Jui, Yuta Tanoue, Dongsu Ryu, Federico R. Urban, Nobuyuki Sakurai, Motoki Hayashi, BayarJon Paul Lubsandorzhiev, Mayuko Minamino, Kenta Yashiro, Yuto Kubota, Saori Kasami, Kozo Fujisue, Tsubasa Yoshioka, John Matthews, Hirokazu Iwakura, Shingo Kawana, Y. Takagi, Ryosuke Tsuda, Soomin Jeong, Yasunori Saito, Zach Zundel, J. Yang, William Hanlon, Fumio Kakimoto, Grigory Rubtsov, Ryuji Takeishi, Tatsunobu Shibata, Samuel Blake, Shoichi Ogio, T. Seki, Akitoshi Oshima, Yuya Oku, M. Ohnishi, Ryota Fujiwara, Taichi Inadomi, Y. Nakamura, Oleg Kalashev, Kohei Yada, Keitaro Fujita, Shunsuke Ozawa, Koki Sato, Yuichiro Tameda, Monica Allen, Bokkyun Shin, Naoto Sakaki, Naoya Inoue, Kengo Sano, Ryota Fukushima, Hirotaka Ito, Youngjoon Kwon, Ivan Kharuk, Masato Takita, John Belz, Norimichi Shibata, Y. Omura, Elliott Barcikowski, Dmitri Ivanov, Keijiro Mukai, Yusuke Kimura, Hideaki Shimodaira, Hyoming Jeong, Kinya Hibino, Ryo Higuchi, Toshio Matsuyama, K. Yamazaki, Tareq Abu-Zayyad, Manobu Tanaka, K. H. Lee, Jihee Kim, Gordon Thomson, Tom Stroman, Akimichi Taketa, Robert Cady, Mikhail Kuznetsov, Eiji Nishio, M. Yamamoto, Yukio Uchihori, Ryota Onogi, J. H. Kim, R. Mayta, Shigeharu Udo, Hideyuki Kawai, Shinnosuke Kurisu, Ryo Nakamura, Jeremy Smith, Yuma Shibasaki, Min Hyo Kim, Douglas Bergman, S. Kawakami, Hiroyuki Sagawa, Koichi Tanaka, Jon Paul Lundquist, and Sergey Troitsky

Subjects
Physics, Energy spectrum, Cosmic ray, Knee region, Astrophysics
Published
2021
Full Text
View/download PDF

39. Cosmic Ray Composition between 2 PeV and 2 EeV measured by the TALE Fluorescence Detector

Author

Shigeharu Udo, Daiki Shinto, Fumiya Shibata, Priti Shah, Stanton Thomas, Norimichi Shibata, Y. Omura, Matt Potts, Masahiro Takeda, Ken Honda, Ryo Nakamura, Youngjoon Kwon, Vladim Kuzmin, John Belz, Telescope Array, Yasunori Saito, Shinnosuke Kurisu, Yuta Tanoue, Motoki Hayashi, Tatsunobu Shibata, ByongGu Cheon, Saori Kasami, M. Yamamoto, Takeshi Okuda, Igor Tkachev, Naohiro Sone, Fumio Kakimoto, John N. Matthews, K. H. Lee, Jihee Kim, Tomoyuki Nakamura, Yukio Uchihori, J. P. Lundquist, Akitoshi Oshima, Hideyuki Ohoka, Michiyuki Chikawa, Toru Nakamura, Fugo Yoshida, Ryota Onogi, J. H. Kim, Keitaro Fujita, Kozo Fujisue, Hideki Tanaka, Shunsuke Ozawa, Jeremy Smith, Kenichi Kadota, Il Hung Park, H. Oda, Takashi Sako, Charlie Jui, Hiroyuki Matsumiya, R. Mayta, Shoichi Kishigami, Akimichi Taketa, Gordon Thomson, Hisono Tokuno, BayarJon Paul Lubsandorzhiev, Mayuko Minamino, Takafumi Uehama, Ryota Fujiwara, Eiji Nishio, Sergey Troitsky, Kinya Hibino, Min Hyo Kim, Masaomi Ono, Maxim Pshirkov, Tom Stroman, Robert Cady, Pierre Sokolsky, Taka Tomida, Shingo Kawana, Eiji Kido, Kazuhiro Machida, J. Remington, Naoto Sakaki, Katsuaki Kasahara, Shigehiro Nagataki, Yana Zhezher, M. Ohnishi, Taichi Inadomi, Yuto Kubota, Zach Zundel, Ben Stokes, William Hanlon, Sang Woo Kim, Koki Sato, Federico R. Urban, Nobuyuki Sakurai, Hideyuki Kawai, Yuma Shibasaki, Ryuhei Arimura, Katsumasa Kawata, J. Yang, Koichi Sekino, Monica Allen, Bokkyun Shin, Naoaki Hayashida, Kengo Sano, P. Tinyakov, Yoshiki Tsunesada, Daisuke Ikeda, Y. Nakamura, Douglas Bergman, Kohei Yada, S. Kawakami, Kenta Yashiro, Y. Takahashi, Mai Takamura, Tiffany Wong, Heungsu Shin, Tsubasa Yoshioka, Masaki Fukushima, Yuya Oku, Oleg Kalashev, Hiroyuki Sagawa, Samuel Blake, Shoichi Ogio, Toshiyuki Nonaka, Ricardo Gonzalez, Yuichiro Tameda, Yuto Arai, Koichi Tanaka, Rasha Abbasi, T. Fujii, Masato Takita, Toshio Matsuyama, Elliott Barcikowski, Dmitri Ivanov, Keijiro Mukai, Manobu Tanaka, Yusuke Kimura, Ryosuke Tsuda, Soomin Jeong, T. Seki, Naoya Inoue, Arata Nakazawa, Kei Nakai, G. Furlich, Takaaki Ishii, D. C. Rodriguez, HangBae Kim, Isaac Myers, Hideaki Shimodaira, Hyoming Jeong, Ryo Higuchi, K. Yamazaki, Tareq Abu-Zayyad, Mikhail Kuznetsov, Grigory Rubtsov, Hirotaka Ito, Aoi Iwasaki, Ivan Kharuk, Ryuji Takeishi, R. Sahara, Ryota Fukushima, Jyunsei Chiba, Dongsu Ryu, Hirokazu Iwakura, and Y. Takagi

Subjects
Physics, Cosmic ray, Astrophysics, Fluorescence spectroscopy
Published
2021
Full Text
View/download PDF

40. The status of the TALE surface detector array and TALE infill project

Author

Takashi Sako, Zach Zundel, Shigeharu Udo, Kenta Yashiro, Toru Nakamura, Kenichi Kadota, Il Hung Park, Min Hyo Kim, Ryo Nakamura, Tatsunobu Shibata, R. Sahara, Noemie Globus, Elliott Barcikowski, S. Kawakami, Akitoshi Oshima, Dmitri Ivanov, Grigory Rubtsov, Fugo Yoshida, Shunsuke Ozawa, Keijiro Mukai, Charlie Jui, BayarJon Paul Lubsandorzhiev, Yusuke Kimura, Fumio Kakimoto, Mayuko Minamino, Saori Kasami, G. Furlich, Takaaki Ishii, Norimichi Shibata, Fumiya Shibata, Hiroyuki Sagawa, Y. Omura, D. C. Rodriguez, Matt Potts, Aoi Iwasaki, HangBae Kim, Koichi Tanaka, Jon Paul Lundquist, Ryota Fukushima, Monica Allen, Bokkyun Shin, Yuya Oku, Ryuji Takeishi, Vladim Kuzmin, Oleg Kalashev, Telescope Array, M. Yamamoto, Youngjoon Kwon, Arata Nakazawa, John Belz, Kei Nakai, Yukio Uchihori, Stanton Thomas, Yasunori Saito, Maxim Pshirkov, Michiyuki Chikawa, Ben Stokes, Ryota Onogi, J. H. Kim, Hirotaka Ito, R. Mayta, Ryuhei Arimura, Shoichi Kishigami, Pierre Sokolsky, Federico R. Urban, Nobuyuki Sakurai, Hideki Tanaka, Kinya Hibino, Yoshiki Tsunesada, Shigehiro Nagataki, Yana Zhezher, Masaomi Ono, Sang Woo Kim, Sergey Troitsky, Hisono Tokuno, Taka Tomida, J. Remington, Rasha Abbasi, M. Ohnishi, Taichi Inadomi, Naoaki Hayashida, Hideaki Shimodaira, Hyoming Jeong, Isaac Myers, Koki Sato, Ryo Higuchi, Toshihiro Fujii, Tomoyuki Nakamura, Hiroyuki Matsumiya, Ryota Fujiwara, Takafumi Uehama, ByongGu Cheon, Yuto Kubota, Eiji Kido, Naoto Sakaki, Kazuhiro Machida, Kengo Sano, Katsuaki Kasahara, K. Yamazaki, Katsumasa Kawata, Tareq Abu-Zayyad, Tsubasa Yoshioka, Takeshi Okuda, Igor Tkachev, Y. Nakamura, Kohei Yada, Naohiro Sone, Mikhail Kuznetsov, Hideyuki Ohoka, H. Oda, Akimichi Taketa, Eiji Nishio, Ivan Kharuk, Hideyuki Kawai, Yuma Shibasaki, Jyunsei Chiba, Dongsu Ryu, Hirokazu Iwakura, Y. Takagi, Douglas Bergman, Shinnosuke Kurisu, Jeremy Smith, Toshio Matsuyama, K. H. Lee, Jihee Kim, Gordon Thomson, Tom Stroman, Robert Cady, Manobu Tanaka, Keitaro Fujita, Daiki Shinto, Priti Shah, Masahiro Takeda, Ken Honda, John Matthews, J. Yang, Koichi Sekino, P. Tinyakov, Y. Takahashi, Mai Takamura, Daisuke Ikeda, Tiffany Wong, Masaki Fukushima, Yuta Tanoue, Motoki Hayashi, Heungsu Shin, Kozo Fujisue, Yuto Arai, Ryosuke Tsuda, Soomin Jeong, Shingo Kawana, William Hanlon, T. Seki, Toshiyuki Nonaka, Ricardo Gonzalez, Naoya Inoue, Yuichiro Tameda, Masato Takita, Samuel Blake, and Shoichi Ogio

Subjects
Surface (mathematics), Optics, business.industry, Infill, Detector array, business, Geology
Published
2021
Full Text
View/download PDF

41. Current status and prospects of surface detector of the TAx4 experiment

Author

Katsumasa Kawata, Grigory Rubtsov, Tsubasa Yoshioka, Tatsunobu Shibata, Yuichiro Tameda, Kenta Yashiro, Akitoshi Oshima, Fugo Yoshida, Jyunsei Chiba, Ryosuke Tsuda, Soomin Jeong, M. Yamamoto, Ryo Nakamura, Shunsuke Ozawa, Dongsu Ryu, Takashi Sako, Shingo Kawana, Hirokazu Iwakura, Y. Takagi, ByongGu Cheon, T. Seki, Naoya Inoue, Yukio Uchihori, Hideaki Shimodaira, Hyoming Jeong, Hideki Tanaka, Aoi Iwasaki, John Matthews, Ryota Onogi, J. H. Kim, William Hanlon, Ryo Higuchi, Fumiya Shibata, J. Yang, Hisono Tokuno, Masato Takita, Akimichi Taketa, M. Ohnishi, Taichi Inadomi, Hideyuki Ohoka, Ryota Fujiwara, Youngjoon Kwon, John Belz, R. Mayta, Yuta Tanoue, Koki Sato, Eiji Nishio, Motoki Hayashi, Naoto Sakaki, Ryota Fukushima, Matt Potts, Ivan Kharuk, K. Yamazaki, Ben Stokes, Sergey Troitsky, Min Hyo Kim, Tareq Abu-Zayyad, Kengo Sano, Kozo Fujisue, Zach Zundel, Kinya Hibino, Saori Kasami, Toru Nakamura, R. Sahara, Taka Tomida, J. Remington, Federico R. Urban, Nobuyuki Sakurai, Takeshi Okuda, Igor Tkachev, Naohiro Sone, Samuel Blake, Shoichi Ogio, Kenichi Kadota, Il Hung Park, Hideyuki Kawai, Rasha Abbasi, Keitaro Fujita, Koichi Sekino, H. Oda, Mikhail Kuznetsov, Heungsu Shin, Shinnosuke Kurisu, Toshiyuki Nonaka, Ricardo Gonzalez, P. Tinyakov, S. Kawakami, Charlie Jui, Fumio Kakimoto, Yuto Arai, Naoaki Hayashida, Shigeharu Udo, Yuya Oku, Michiyuki Chikawa, Oleg Kalashev, BayarJon Paul Lubsandorzhiev, Mayuko Minamino, Y. Takahashi, Mai Takamura, Jeremy Smith, Ryuhei Arimura, Daiki Shinto, Monica Allen, Bokkyun Shin, Yuma Shibasaki, Priti Shah, Hiroyuki Sagawa, Masahiro Takeda, Vladim Kuzmin, Yoshiki Tsunesada, Daisuke Ikeda, Ken Honda, Toshio Matsuyama, Douglas Bergman, Tiffany Wong, Koichi Tanaka, Masaki Fukushima, Jon Paul Lundquist, Elliott Barcikowski, Dmitri Ivanov, Keijiro Mukai, Yusuke Kimura, Manobu Tanaka, K. H. Lee, Jihee Kim, Maxim Pshirkov, Gordon Thomson, Toshihiro Fujii, Tom Stroman, Robert Cady, Yuto Kubota, Y. Nakamura, Kohei Yada, Pierre Sokolsky, Shigehiro Nagataki, Shoichi Kishigami, Yana Zhezher, Sang Woo Kim, Masaomi Ono, Telescope Array, Tomoyuki Nakamura, Stanton Thomas, Hiroyuki Matsumiya, Takafumi Uehama, Eiji Kido, Kazuhiro Machida, Yasunori Saito, Isaac Myers, Norimichi Shibata, Y. Omura, G. Furlich, Takaaki Ishii, D. C. Rodriguez, HangBae Kim, Arata Nakazawa, Kei Nakai, Hirotaka Ito, Ryuji Takeishi, and Katsuaki Kasahara

Subjects
Physics, Surface (mathematics), Optics, business.industry, Detector, Current (fluid), business
Published
2021
Full Text
View/download PDF

42. Cosmic Ray Composition in the Second Knee Region as Measured by the TALE Hybrid Detector

Author

ByongGu Cheon, Hiroyuki Matsumiya, Charlie Jui, BayarJon Paul Lubsandorzhiev, Mayuko Minamino, Takashi Sako, Ivan Kharuk, Takeshi Okuda, Igor Tkachev, Takafumi Uehama, Hideyuki Ohoka, Daiki Shinto, Priti Shah, Isaac Myers, K. H. Lee, Jihee Kim, Telescope Array, Naohiro Sone, Eiji Kido, Fugo Yoshida, Kazuhiro Machida, Aoi Iwasaki, Hideaki Shimodaira, Hyoming Jeong, Masahiro Takeda, Ken Honda, H. Oda, Zach Zundel, Yuta Tanoue, Fumiya Shibata, Gordon Thomson, Tom Stroman, Robert Cady, Shoichi Kishigami, Ryo Higuchi, Youngjoon Kwon, Sergey Troitsky, Motoki Hayashi, Masaomi Ono, John Belz, Kozo Fujisue, Stanton Thomas, Kinya Hibino, Elliott Barcikowski, Matt Potts, Taka Tomida, Dmitri Ivanov, John Matthews, Samuel Blake, Ryuhei Arimura, J. Remington, M. Ohnishi, Taichi Inadomi, Koichi Sekino, Shoichi Ogio, Keijiro Mukai, J. Yang, P. Tinyakov, K. Yamazaki, G. Furlich, Takaaki Ishii, Pierre Sokolsky, Norimichi Shibata, Yuichiro Tameda, Shingo Kawana, Yusuke Kimura, Y. Omura, Tareq Abu-Zayyad, Yoshiki Tsunesada, Ryuji Takeishi, Daisuke Ikeda, Y. Takahashi, Mai Takamura, Koki Sato, Shigehiro Nagataki, Yana Zhezher, Jyunsei Chiba, Dongsu Ryu, William Hanlon, Hiroyuki Sagawa, Shigeharu Udo, Sang Woo Kim, D. C. Rodriguez, Kengo Sano, Tatsunobu Shibata, Tiffany Wong, Hirokazu Iwakura, Y. Takagi, HangBae Kim, Toshihiro Fujii, Mikhail Kuznetsov, Masato Takita, Keitaro Fujita, Yasunori Saito, Masaki Fukushima, Akitoshi Oshima, Yuto Kubota, Vladim Kuzmin, Kenta Yashiro, Grigory Rubtsov, Shunsuke Ozawa, Tomoyuki Nakamura, Manobu Tanaka, Y. Nakamura, Kohei Yada, Koichi Tanaka, Ryosuke Tsuda, Fumio Kakimoto, Ben Stokes, Ryota Fukushima, Naoaki Hayashida, M. Yamamoto, Monica Allen, Bokkyun Shin, Soomin Jeong, Michiyuki Chikawa, R. Sahara, Jon Paul Lundquist, Federico R. Urban, Arata Nakazawa, Nobuyuki Sakurai, Toshiyuki Nonaka, Yukio Uchihori, Kei Nakai, Ryota Onogi, J. H. Kim, Ricardo Gonzalez, Maxim Pshirkov, Toshio Matsuyama, T. Seki, Naoya Inoue, R. Mayta, Hirotaka Ito, Min Hyo Kim, S. Kawakami, Heungsu Shin, Yuto Arai, Saori Kasami, Ryo Nakamura, Hideki Tanaka, Hisono Tokuno, Yuma Shibasaki, Douglas Bergman, Akimichi Taketa, Eiji Nishio, Yuya Oku, Hideyuki Kawai, Shinnosuke Kurisu, Oleg Kalashev, Jeremy Smith, Toru Nakamura, Kenichi Kadota, Il Hung Park, Ryota Fujiwara, Naoto Sakaki, Katsuaki Kasahara, Katsumasa Kawata, Tsubasa Yoshioka, and Rasha Abbasi

Subjects
Physics, Detector, Cosmic ray, Knee region, Astrophysics, Composition (combinatorics)
Published
2021
Full Text
View/download PDF

43. Effects of Galactic magnetic field on the UHECR anisotropy studies

Author

Tomoyuki Nakamura, Sergey Troitsky, Taka Tomida, M. Yamamoto, Fugo Yoshida, J. Remington, M. Ohnishi, Taichi Inadomi, Elliott Barcikowski, Stanton Thomas, Pierre Sokolsky, Yuichiro Tameda, Hideaki Shimodaira, Hyoming Jeong, Dmitri Ivanov, R. Sahara, Shigehiro Nagataki, Yana Zhezher, Ryota Fujiwara, Sang Woo Kim, Yukio Uchihori, Manobu Tanaka, Ryo Higuchi, Ivan Kharuk, Keijiro Mukai, Koki Sato, ByongGu Cheon, Norimichi Shibata, Yuma Shibasaki, Ryota Onogi, J. H. Kim, Y. Omura, Keitaro Fujita, Naoto Sakaki, Aoi Iwasaki, Yusuke Kimura, K. H. Lee, Jihee Kim, Hideyuki Ohoka, R. Mayta, Kengo Sano, Gordon Thomson, K. Yamazaki, Tom Stroman, Robert Cady, Tareq Abu-Zayyad, Kinya Hibino, Toru Nakamura, Yasunori Saito, Douglas Bergman, Naoaki Hayashida, Takeshi Okuda, Igor Tkachev, Mikhail Kuznetsov, Min Hyo Kim, Kenichi Kadota, Michiyuki Chikawa, Rasha Abbasi, Ryosuke Tsuda, Yuta Tanoue, Naohiro Sone, Il Hung Park, Masato Takita, Soomin Jeong, John N. Matthews, Katsuaki Kasahara, H. Oda, Saori Kasami, Shinnosuke Kurisu, Motoki Hayashi, Takashi Sako, Katsumasa Kawata, Youngjoon Kwon, John Belz, Ben Stokes, J. P. Lundquist, Arata Nakazawa, S. Kawakami, Monica Allen, Bokkyun Shin, T. Seki, Yuto Kubota, Kozo Fujisue, Federico R. Urban, Hiroyuki Matsumiya, Nobuyuki Sakurai, Tsubasa Yoshioka, Naoya Inoue, Vladim Kuzmin, J. Yang, Shigeharu Udo, Kei Nakai, Kenta Yashiro, T. Fujii, Hiroyuki Sagawa, Maxim Pshirkov, Takafumi Uehama, Shingo Kawana, Kazumasa Kawata, Toshio Matsuyama, Y. Nakamura, Jeremy Smith, Yuya Oku, Kohei Yada, Koichi Tanaka, Akimichi Taketa, Koichi Sekino, Hideki Tanaka, Oleg Kalashev, Eiji Kido, Tatsunobu Shibata, William Hanlon, Daiki Shinto, Eiji Nishio, Kazuhiro Machida, Jyunsei Chiba, Dongsu Ryu, Telescope Array, Zach Zundel, Akitoshi Oshima, Priti Shah, P. Tinyakov, Heungsu Shin, Fumio Kakimoto, Shunsuke Ozawa, Isaac Myers, Ryuhei Arimura, Hisono Tokuno, Masahiro Takeda, Ken Honda, Ryuji Takeishi, Yoshiki Tsunesada, Daisuke Ikeda, Hideyuki Kawai, Hirokazu Iwakura, Y. Takagi, Tiffany Wong, Samuel Blake, Masaki Fukushima, Shoichi Ogio, Yuto Arai, Toshiyuki Nonaka, Shoichi Kishigami, Ricardo Gonzalez, G. Furlich, Takaaki Ishii, Y. Takahashi, Mai Takamura, Masaomi Ono, D. C. Rodriguez, HangBae Kim, Grigory Rubtsov, Ryota Fukushima, Hirotaka Ito, Ryo Nakamura, Charlie Jui, BayarJon Paul Lubsandorzhiev, Mayuko Minamino, Fumiya Shibata, and Matt Potts

Subjects
Physics, Astrophysics, Anisotropy, Magnetic field
Published
2021
Full Text
View/download PDF

44. Mass composition of Telescope Array's surface detectors events using deep learning

Author

Hideaki Shimodaira, Hyoming Jeong, Hiroyuki Sagawa, Fumiya Shibata, Ryuji Takeishi, Ryo Higuchi, Youngjoon Kwon, John Belz, Hideyuki Ohoka, Ryo Nakamura, Rasha Abbasi, Daiki Shinto, Ryuhei Arimura, Koichi Tanaka, Yoshiki Tsunesada, Daisuke Ikeda, Michiyuki Chikawa, Tiffany Wong, Masaki Fukushima, Matt Potts, Yuma Shibasaki, Priti Shah, Jon Paul Lundquist, K. Yamazaki, Pierre Sokolsky, Katsuaki Kasahara, Katsumasa Kawata, Tareq Abu-Zayyad, Fugo Yoshida, Masahiro Takeda, Takashi Sako, Ken Honda, Zach Zundel, Shigehiro Nagataki, Yana Zhezher, Ben Stokes, Tsubasa Yoshioka, Kenta Yashiro, Sergey Troitsky, R. Sahara, Douglas Bergman, Sang Woo Kim, Taka Tomida, Shingo Kawana, Charlie Jui, BayarJon Paul Lubsandorzhiev, J. Remington, Mayuko Minamino, Mikhail Kuznetsov, Min Hyo Kim, Shinnosuke Kurisu, William Hanlon, Ryota Fujiwara, Elliott Barcikowski, Dmitri Ivanov, Monica Allen, Naoto Sakaki, Tomoyuki Nakamura, G. Furlich, Takaaki Ishii, Federico R. Urban, Nobuyuki Sakurai, Saori Kasami, Keijiro Mukai, Bokkyun Shin, Toshio Matsuyama, K. H. Lee, Jihee Kim, Gordon Thomson, Ryota Fukushima, Samuel Blake, Shoichi Ogio, Hirotaka Ito, Yusuke Kimura, Tom Stroman, Robert Cady, Naoaki Hayashida, Norimichi Shibata, Y. Omura, S. Kawakami, D. C. Rodriguez, Keitaro Fujita, Jeremy Smith, HangBae Kim, Takeshi Okuda, Igor Tkachev, Akimichi Taketa, Hideki Tanaka, Stanton Thomas, Naohiro Sone, Isaac Myers, Eiji Nishio, Yuya Oku, Aoi Iwasaki, Oleg Kalashev, Hiroyuki Matsumiya, Toshihiro Fujii, Hisono Tokuno, H. Oda, Jyunsei Chiba, Grigory Rubtsov, Dongsu Ryu, Manobu Tanaka, Yuto Kubota, Koichi Sekino, Takafumi Uehama, Maxim Pshirkov, Hideyuki Kawai, P. Tinyakov, Toru Nakamura, Kenichi Kadota, M. Ohnishi, Y. Nakamura, Il Hung Park, Kohei Yada, Hirokazu Iwakura, Taichi Inadomi, Y. Takagi, Y. Takahashi, Mai Takamura, Eiji Kido, Kazuhiro Machida, Arata Nakazawa, Koki Sato, John Matthews, Toshiyuki Nonaka, Kei Nakai, Ivan Kharuk, J. Yang, Ricardo Gonzalez, Kengo Sano, Yasunori Saito, Yuta Tanoue, Fumio Kakimoto, Motoki Hayashi, Yuichiro Tameda, Kozo Fujisue, Shoichi Kishigami, Masaomi Ono, Masato Takita, Telescope Array, Shigeharu Udo, Kinya Hibino, M. Yamamoto, Yukio Uchihori, Ryota Onogi, J. H. Kim, R. Mayta, Vladim Kuzmin, Ryosuke Tsuda, Soomin Jeong, T. Seki, Naoya Inoue, Heungsu Shin, Yuto Arai, Tatsunobu Shibata, Akitoshi Oshima, Shunsuke Ozawa, and ByongGu Cheon

Subjects
Surface (mathematics), Telescope, Physics, Optics, business.industry, law, Deep learning, Detector, Artificial intelligence, Mass composition, business, law.invention
Published
2021
Full Text
View/download PDF

45. FOV direction and image size calibration of Fluorescence Detector using light source on UAV

Author

Telescope Array, Yasunori Saito, Shoichi Kishigami, Hideaki Shimodaira, Hyoming Jeong, Masaomi Ono, Ryo Higuchi, Ryuhei Arimura, Fugo Yoshida, Ryo Nakamura, Tomoyuki Nakamura, Charlie Jui, Min Hyo Kim, M. Ohnishi, Taichi Inadomi, Hideki Tanaka, Hisono Tokuno, BayarJon Paul Lubsandorzhiev, John Matthews, Yoshiki Tsunesada, Heungsu Shin, Manobu Tanaka, Koki Sato, Mayuko Minamino, J. Yang, Daisuke Ikeda, K. Yamazaki, Tareq Abu-Zayyad, M. Yamamoto, S. Kawakami, Kengo Sano, Sergey Troitsky, Fumio Kakimoto, Yuto Arai, Tiffany Wong, Taka Tomida, J. Remington, Koichi Sekino, Stanton Thomas, Kenta Yashiro, Ryosuke Tsuda, Saori Kasami, Monica Allen, Yukio Uchihori, Masaki Fukushima, Fumiya Shibata, Ben Stokes, Toshio Matsuyama, P. Tinyakov, Mikhail Kuznetsov, Soomin Jeong, Bokkyun Shin, Pierre Sokolsky, Norimichi Shibata, Hiroyuki Sagawa, K. H. Lee, Jihee Kim, Y. Omura, Ryota Onogi, J. H. Kim, Gordon Thomson, G. Furlich, Takaaki Ishii, Tom Stroman, Robert Cady, Y. Takahashi, Mai Takamura, ByongGu Cheon, Matt Potts, Shigehiro Nagataki, Yana Zhezher, Keitaro Fujita, Federico R. Urban, Nobuyuki Sakurai, Koichi Tanaka, Naoaki Hayashida, T. Seki, Naoya Inoue, R. Mayta, Jon Paul Lundquist, Sang Woo Kim, Hiroyuki Matsumiya, Yuta Tanoue, Yuichiro Tameda, Kinya Hibino, Motoki Hayashi, Takafumi Uehama, D. C. Rodriguez, Eiji Kido, Maxim Pshirkov, Kozo Fujisue, Takeshi Okuda, Kazuhiro Machida, HangBae Kim, Hideyuki Ohoka, Igor Tkachev, Naohiro Sone, Shigeharu Udo, Shinnosuke Kurisu, Grigory Rubtsov, Tatsunobu Shibata, H. Oda, Michiyuki Chikawa, Daiki Shinto, Arata Nakazawa, Kei Nakai, Akitoshi Oshima, Priti Shah, R. Sahara, Jeremy Smith, Akimichi Taketa, Eiji Nishio, Masahiro Takeda, Takashi Sako, Vladim Kuzmin, Ken Honda, Masato Takita, Shunsuke Ozawa, Isaac Myers, Hideyuki Kawai, Yuma Shibasaki, Douglas Bergman, Samuel Blake, Shoichi Ogio, Zach Zundel, Jyunsei Chiba, Dongsu Ryu, Hirokazu Iwakura, Y. Takagi, Ivan Kharuk, Toru Nakamura, Elliott Barcikowski, Kenichi Kadota, Dmitri Ivanov, Il Hung Park, Keijiro Mukai, Yusuke Kimura, Yuya Oku, Oleg Kalashev, Ryota Fukushima, Youngjoon Kwon, John Belz, Toshihiro Fujii, Yuto Kubota, Y. Nakamura, Kohei Yada, Hirotaka Ito, Rasha Abbasi, Aoi Iwasaki, Ryota Fujiwara, Naoto Sakaki, Katsuaki Kasahara, Katsumasa Kawata, Tsubasa Yoshioka, Ryuji Takeishi, Shingo Kawana, William Hanlon, Toshiyuki Nonaka, and Ricardo Gonzalez

Subjects
Physics, Light source, Optics, business.industry, Calibration, business, Image resolution, Fluorescence spectroscopy
Published
2021
Full Text
View/download PDF

46. UHECR mass composition from anisotropy of their arrival directions with the Telescope Array SD

Author

Katsuaki Kasahara, Ryota Fukushima, Takeshi Okuda, Igor Tkachev, Katsumasa Kawata, Daiki Shinto, Naohiro Sone, ByongGu Cheon, Shoichi Kishigami, Norimichi Shibata, Manobu Tanaka, Grigory Rubtsov, Ryuhei Arimura, M. Yamamoto, H. Oda, Masaomi Ono, Priti Shah, Y. Omura, Yoshiki Tsunesada, Tsubasa Yoshioka, Daisuke Ikeda, Masahiro Takeda, Tiffany Wong, Mikhail Kuznetsov, Ken Honda, K. H. Lee, Jihee Kim, Kenta Yashiro, Gordon Thomson, Hideyuki Ohoka, Yuichiro Tameda, Yukio Uchihori, Masaki Fukushima, Hiroyuki Sagawa, R. Sahara, Charlie Jui, Jyunsei Chiba, Dongsu Ryu, Tom Stroman, Fugo Yoshida, Robert Cady, Ryota Onogi, J. H. Kim, Shinnosuke Kurisu, Shingo Kawana, Ryota Fujiwara, BayarJon Paul Lubsandorzhiev, William Hanlon, Hirokazu Iwakura, Y. Takagi, R. Mayta, Hiroyuki Matsumiya, Koichi Tanaka, Mayuko Minamino, Vladim Kuzmin, Hideaki Shimodaira, Ivan Kharuk, Jon Paul Lundquist, Naoto Sakaki, Youngjoon Kwon, Kinya Hibino, John Belz, Ryo Nakamura, Hyoming Jeong, Michiyuki Chikawa, Keitaro Fujita, Takafumi Uehama, Saori Kasami, Fumiya Shibata, Ryo Higuchi, Yuya Oku, M. Ohnishi, Takashi Sako, Masato Takita, Eiji Kido, Toshiyuki Nonaka, Taichi Inadomi, Oleg Kalashev, Ryosuke Tsuda, Soomin Jeong, Ricardo Gonzalez, Rasha Abbasi, Kazuhiro Machida, Toshio Matsuyama, Min Hyo Kim, Matt Potts, Koki Sato, Kengo Sano, K. Yamazaki, Tareq Abu-Zayyad, Hideki Tanaka, Zach Zundel, S. Kawakami, Yasunori Saito, Peter Tinyakov, Samuel Blake, Shoichi Ogio, Shigeharu Udo, T. Seki, Toru Nakamura, Naoya Inoue, Jeremy Smith, John Matthews, J. Yang, Monica Allen, Kenichi Kadota, Hisono Tokuno, Yuta Tanoue, Akimichi Taketa, Bokkyun Shin, Eiji Nishio, Il Hung Park, Motoki Hayashi, Ben Stokes, Kozo Fujisue, Heungsu Shin, Federico R. Urban, Nobuyuki Sakurai, Hideyuki Kawai, Yuma Shibasaki, Koichi Sekino, Yuto Arai, Douglas Bergman, Tatsunobu Shibata, Y. Takahashi, Mai Takamura, Akitoshi Oshima, Shunsuke Ozawa, Maxim Pshirkov, Fumio Kakimoto, Sergey Troitsky, Taka Tomida, J. Remington, Naoaki Hayashida, Toshihiro Fujii, Yuto Kubota, Y. Nakamura, Kohei Yada, Elliott Barcikowski, Dmitri Ivanov, Keijiro Mukai, Yusuke Kimura, Stanton Thomas, Aoi Iwasaki, Tomoyuki Nakamura, Ryuji Takeishi, Pierre Sokolsky, Shigehiro Nagataki, Yana Zhezher, Isaac Myers, Sang Woo Kim, Hirotaka Ito, G. Furlich, Takaaki Ishii, D. C. Rodriguez, HangBae Kim, Arata Nakazawa, and Kei Nakai

Subjects
Telescope, Physics, law, Astrophysics, Mass composition, Anisotropy, law.invention
Published
2021
Full Text
View/download PDF

47. Analysis of TAx4 hybrid trigger and events

Author

Ivan Kharuk, Yuma Shibasaki, Jyunsei Chiba, Dongsu Ryu, Aoi Iwasaki, Hirokazu Iwakura, Y. Takagi, K. H. Lee, Jihee Kim, Ryota Fukushima, Ryuhei Arimura, Shigeharu Udo, Fumiya Shibata, Gordon Thomson, Hideki Tanaka, Fugo Yoshida, Tom Stroman, Robert Cady, Yoshiki Tsunesada, Sergey Troitsky, Daisuke Ikeda, Douglas Bergman, Taka Tomida, J. Remington, Tiffany Wong, John Matthews, ByongGu Cheon, Hiroyuki Matsumiya, Ryo Nakamura, Ryuji Takeishi, Masaki Fukushima, Hisono Tokuno, Ryosuke Tsuda, Soomin Jeong, M. Yamamoto, J. Yang, Matt Potts, Pierre Sokolsky, Min Hyo Kim, Yukio Uchihori, Naoaki Hayashida, Takashi Sako, T. Seki, Shigehiro Nagataki, Yana Zhezher, Akimichi Taketa, Naoya Inoue, Tatsunobu Shibata, Daiki Shinto, Sang Woo Kim, Eiji Nishio, Ryota Onogi, J. H. Kim, Priti Shah, Takafumi Uehama, G. Furlich, Takaaki Ishii, Saori Kasami, Hideaki Shimodaira, Hyoming Jeong, Masahiro Takeda, Charlie Jui, Ken Honda, R. Mayta, S. Kawakami, Heungsu Shin, BayarJon Paul Lubsandorzhiev, Ryo Higuchi, Toru Nakamura, Yuta Tanoue, Mayuko Minamino, Kenichi Kadota, Zach Zundel, Akitoshi Oshima, Eiji Kido, Elliott Barcikowski, Shingo Kawana, Shoichi Kishigami, Yuto Arai, Keitaro Fujita, Motoki Hayashi, Yuichiro Tameda, Hideyuki Ohoka, Il Hung Park, Kinya Hibino, Hirotaka Ito, Toshio Matsuyama, Kazuhiro Machida, Hiroyuki Sagawa, Hideyuki Kawai, D. C. Rodriguez, Dmitri Ivanov, Vladim Kuzmin, William Hanlon, Stanton Thomas, HangBae Kim, Shinnosuke Kurisu, Kozo Fujisue, Keijiro Mukai, K. Yamazaki, Masaomi Ono, Michiyuki Chikawa, Tareq Abu-Zayyad, Yusuke Kimura, Yasunori Saito, Koichi Tanaka, Grigory Rubtsov, Tomoyuki Nakamura, Jon Paul Lundquist, Koichi Sekino, Shunsuke Ozawa, Yuya Oku, P. Tinyakov, Isaac Myers, Oleg Kalashev, Masato Takita, Y. Takahashi, Mai Takamura, R. Sahara, Telescope Array, S. W. Kim, Manobu Tanaka, Toshiyuki Nonaka, Jeremy Smith, Norimichi Shibata, Y. Omura, Mikhail Kuznetsov, Ricardo Gonzalez, Ben Stokes, Samuel Blake, Toshihiro Fujii, Monica Allen, Shoichi Ogio, Yuto Kubota, Bokkyun Shin, Y. Nakamura, Kohei Yada, Federico R. Urban, Arata Nakazawa, Nobuyuki Sakurai, Kei Nakai, Youngjoon Kwon, John Belz, Rasha Abbasi, M. Ohnishi, Taichi Inadomi, Koki Sato, Fumio Kakimoto, Ryota Fujiwara, Kengo Sano, Naoto Sakaki, Katsuaki Kasahara, Katsumasa Kawata, Kenta Yashiro, Tsubasa Yoshioka, Maxim Pshirkov, Takeshi Okuda, Igor Tkachev, Naohiro Sone, and H. Oda

Published
2021
Full Text
View/download PDF

48. Reconstruction of air shower events measured by the surface detectors of the TAx4 experiment

Author

Fugo Yoshida, Fumio Kakimoto, Norimichi Shibata, Kinya Hibino, John Matthews, J. Yang, Y. Omura, Ivan Kharuk, Toshihiro Fujii, Hiroyuki Sagawa, Yuichiro Tameda, Hideki Tanaka, Yuma Shibasaki, Yuto Kubota, Hisono Tokuno, Mikhail Kuznetsov, Katsuaki Kasahara, Koichi Tanaka, Jon Paul Lundquist, M. Yamamoto, Katsumasa Kawata, Monica Allen, Bokkyun Shin, Hiroyuki Matsumiya, Tsubasa Yoshioka, Takafumi Uehama, Y. Nakamura, Kohei Yada, Yukio Uchihori, Hyomin Jeong, Tatsunobu Shibata, Ryota Onogi, J. H. Kim, Michiyuki Chikawa, ByongGu Cheon, Hideaki Shimodaira, Hyoming Jeong, Eiji Kido, M. Ohnishi, Taichi Inadomi, Kazuhiro Machida, Ryo Higuchi, Charlie Jui, Akitoshi Oshima, R. Mayta, Douglas Bergman, Keitaro Fujita, Elliott Barcikowski, Maxim Pshirkov, Manobu Tanaka, Pierre Sokolsky, Vladim Kuzmin, BayarJon Paul Lubsandorzhiev, Shunsuke Ozawa, Min Hyo Kim, Dmitri Ivanov, Koki Sato, Mayuko Minamino, Saori Kasami, Shigehiro Nagataki, Hideyuki Ohoka, Takashi Sako, K. Yamazaki, Tareq Abu-Zayyad, Keijiro Mukai, Youngjoon Kwon, Yasunori Saito, John Belz, Yana Zhezher, Sang Woo Kim, S. Kawakami, Jyunsei Chiba, Ryo Nakamura, Masato Takita, Yusuke Kimura, Daiki Shinto, Dongsu Ryu, Yuta Tanoue, Fumiya Shibata, Yuya Oku, K. H. Lee, Jihee Kim, Kengo Sano, Priti Shah, Hirokazu Iwakura, Y. Takagi, Motoki Hayashi, Oleg Kalashev, Kenta Yashiro, Zach Zundel, Masahiro Takeda, Ken Honda, Ben Stokes, Matt Potts, Kozo Fujisue, Stanton Thomas, Gordon Thomson, Toshiyuki Nonaka, Ryuhei Arimura, Ryosuke Tsuda, Akimichi Taketa, Tom Stroman, Robert Cady, Soomin Jeong, Ricardo Gonzalez, Federico R. Urban, Nobuyuki Sakurai, Koichi Sekino, Yoshiki Tsunesada, P. Tinyakov, Daisuke Ikeda, Eiji Nishio, T. Seki, Tomoyuki Nakamura, Ryota Fukushima, Naoya Inoue, Tiffany Wong, Toru Nakamura, Kenichi Kadota, Y. Takahashi, Mai Takamura, Masaki Fukushima, Takeshi Okuda, Igor Tkachev, Shingo Kawana, Naohiro Sone, Heungsu Shin, William Hanlon, H. Oda, Il Hung Park, G. Furlich, Takaaki Ishii, Hideyuki Kawai, Shinnosuke Kurisu, Yuto Arai, Toshio Matsuyama, Samuel Blake, Shoichi Ogio, Jeremy Smith, D. C. Rodriguez, Aoi Iwasaki, HangBae Kim, Ryota Fujiwara, Naoto Sakaki, Grigory Rubtsov, Rasha Abbasi, R. Sahara, Arata Nakazawa, Kei Nakai, Telescope Array, Isaac Myers, Hirotaka Ito, Ryuji Takeishi, Shoichi Kishigami, Masaomi Ono, Sergey Troitsky, Taka Tomida, J. Remington, Naoaki Hayashida, and Shigeharu Udo

Subjects
Surface (mathematics), Materials science, Optics, Air shower, business.industry, Detector, business
Published
2021
Full Text
View/download PDF

49. Significance of Elevated HMGB1 Expression in Pituitary Apoplexy

Author

Mitsugu Fujita, Takeshi Okuda, and Amami Kato

Subjects
Adenoma, Adult, Male, Cancer Research, medicine.medical_specialty, Endoscopic surgery, Enzyme-Linked Immunosorbent Assay, chemical and pharmacologic phenomena, Inflammation, Disease, HMGB1, Gastroenterology, Proinflammatory cytokine, 03 medical and health sciences, 0302 clinical medicine, Pituitary adenoma, Internal medicine, medicine, Humans, Pituitary Neoplasms, HMGB1 Protein, biology, business.industry, Pituitary apoplexy, Endoscopy, General Medicine, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Gene Expression Regulation, Neoplastic, Oncology, Biological significance, 030220 oncology & carcinogenesis, biology.protein, Female, medicine.symptom, business, Pituitary Apoplexy
Abstract

Background/aim High-mobility group box 1 (HMGB1) is a nuclear DNA-binding protein that exerts a range of proinflammatory actions when it is secreted extracellularly. We hypothesized that HMGB1 released from damaged cells in pituitary apoplexy would exacerbate the neurological symptoms due to acute inflammation. Patients and methods All the patients included in this study suffered from non-functioning pituitary adenoma. Four patients with apoplexy and three patients without apoplexy were included in this study. They underwent endonasal transsphenoidal endoscopic surgery to resect the tumors. We conducted enzyme-linked immunosorbent assay (ELISA) to measure HMGB1 in the surgical specimens. Results Patients with apoplexy expressed HMGB1 at significantly higher levels than those in the non-apoplexy group (p=0.0478). Conclusion HMGB1 may be involved in subacute inflammation of pituitary apoplexy. Further work is needed to elucidate the detailed biological significance of HMGB1 in this disease.

Published
2019
Full Text
View/download PDF

50. Experience with nasogastric tube administration of tirabrutinib in the treatment of an elderly patient with primary central nervous system lymphoma

Author

Jun C. Takahashi, Mitsugu Fujita, Takeshi Okuda, Takayuki Nakao, and Hiromasa Yoshioka

Subjects
Coma, medicine.medical_specialty, Chemotherapy, business.industry, medicine.medical_treatment, Primary central nervous system lymphoma, Case Report, medicine.disease, Dysphagia, Surgery, Route of administration, Regimen, Oral administration, hemic and lymphatic diseases, medicine, Rituximab, medicine.symptom, business, medicine.drug
Abstract

We report that tirabrutinib was administered via nasogastric tubes to treat an elderly patient with primary central nervous system lymphoma (PCNSL). The patient was a 76-year-old woman who underwent endoscopic biopsy of multiple intracerebral masses, which resulted in the diagnosis of diffuse large B-cell lymphoma. The patient was diagnosed with PCNSL and was started on an induction regimen of systemic chemotherapy with rituximab in combination with high-dose methotrexate. However, after the second cycle of chemotherapy, the tumor grew rapidly, and the patient went into a coma. As a result, the treatment was changed to nasogastric tube administration of tirabrutinib suspension. After 1 week of tirabrutinib administration, the patient’s level of consciousness improved, and furthermore, after 2 weeks of tirabrutinib administration, the patient was able to take tirabrutinib orally. Although oral administration is the standard route of administration for tirabrutinib, this case study showed that the nasogastric tube administration of tirabrutinib suspension is a therapeutic option for patients with impaired consciousness or dysphagia.

Published
2021

Catalog

Books, media, physical & digital resources
See catalog results