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Your search keyword '"Takezawa, Shinichiro"' showing total 23 results
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23 results on '"Takezawa, Shinichiro"'

1. Distinct Function of 2 Chromatin Remodeling Complexes That Share a Common Subunit, Williams Syndrome Transcription Factor (WSTF)

Author

Yoshimura, Kimihiro, Kitagawa, Hirochika, Fujiki, Ryoji, Tanabe, Masahiko, Takezawa, Shinichiro, Takada, Ichiro, Yamaoka, Ikuko, Yonezawa, Masayoshi, Kondo, Takeshi, Furutani, Yoshiyuki, Yagi, Hisato, Yoshinaga, Shin, Masuda, Takeyoshi, Fukuda, Toru, Yamamoto, Yoko, Ebihara, Kanae, Li, Dean Y., Matsuoka, Rumiko, Takeuchi, Jun K., Matsumoto, Takahiro, Kato, Shigeaki, and Groudine, Mark T.

Published
2009
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2. Retraction: ‘A cell cycle‐dependent co‐repressor mediates photoreceptor cell‐specific nuclear receptor function’

Author

Takezawa, Shinichiro, primary, Yokoyama, Atsushi, additional, Okada, Maiko, additional, Fujiki, Ryoji, additional, Iriyama, Aya, additional, Yanagi, Yasuo, additional, Ito, Hiroaki, additional, Takada, Ichiro, additional, Kishimoto, Masahiko, additional, Miyajima, Atsushi, additional, Takeyama, Ken‐ichi, additional, Umesono, Kazuhiko, additional, Kitagawa, Hirochika, additional, and Kato, Shigeaki, additional

Published
2014
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4. Retraction Note: A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-γ transactivation

Author

Takada, Ichiro, primary, Mihara, Masatomo, additional, Suzawa, Miyuki, additional, Ohtake, Fumiaki, additional, Kobayashi, Shinji, additional, Igarashi, Mamoru, additional, Youn, Min-Young, additional, Takeyama, Ken-ichi, additional, Nakamura, Takashi, additional, Mezaki, Yoshihiro, additional, Takezawa, Shinichiro, additional, Yogiashi, Yoshiko, additional, Kitagawa, Hirochika, additional, Yamada, Gen, additional, Takada, Shinji, additional, Minami, Yasuhiro, additional, Shibuya, Hiroshi, additional, Matsumoto, Kunihiro, additional, and Kato, Shigeaki, additional

Published
2014
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5. Retraction Note: DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs

Author

Fukuda, Toru, primary, Yamagata, Kaoru, additional, Fujiyama, Sally, additional, Matsumoto, Takahiro, additional, Koshida, Iori, additional, Yoshimura, Kimihiro, additional, Mihara, Masatomo, additional, Naitou, Masanori, additional, Endoh, Hideki, additional, Nakamura, Takashi, additional, Akimoto, Chihiro, additional, Yamamoto, Yoko, additional, Katagiri, Takenobu, additional, Foulds, Charles, additional, Takezawa, Shinichiro, additional, Kitagawa, Hirochika, additional, Takeyama, Ken-ichi, additional, O'Malley, Bert W., additional, and Kato, Shigeaki, additional

Published
2014
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9. Erratum: A histone lysine methyltransferase activated by non-canonical Wnt signalling supresses PPAR-γ transactivation

Author

Takada, Ichiro, primary, Mihara, Masatomo, additional, Suzawa, Miyuki, additional, Ohtake, Fumiaki, additional, Kobayashi, Shinji, additional, Igarashi, Mamoru, additional, Youn, Min-Young, additional, Takeyama, Ken-ichi, additional, Nakamura, Takashi, additional, Mezaki, Yoshihiro, additional, Takezawa, Shinichiro, additional, Yogiashi, Yoshiko, additional, Kitagawa, Hirochika, additional, Yamada, Gen, additional, Takada, Shinji, additional, Minami, Yasuhiro, additional, Shibuya, Hiroshi, additional, Matsumoto, Kunihiro, additional, and Kato, Shigeaki, additional

Published
2012
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12. A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-γ transactivation

Author

Takada, Ichiro, primary, Mihara, Masatomo, additional, Suzawa, Miyuki, additional, Ohtake, Fumiaki, additional, Kobayashi, Shinji, additional, Igarashi, Mamoru, additional, Youn, Min-Young, additional, Takeyama, Ken-ichi, additional, Nakamura, Takashi, additional, Mezaki, Yoshihiro, additional, Takezawa, Shinichiro, additional, Yogiashi, Yoshiko, additional, Kitagawa, Hirochika, additional, Yamada, Gen, additional, Takada, Shinji, additional, Minami, Yasuhiro, additional, Shibuya, Hiroshi, additional, Matsumoto, Kunihiro, additional, and Kato, Shigeaki, additional

Published
2007
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13. DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs

Author

Fukuda, Toru, primary, Yamagata, Kaoru, additional, Fujiyama, Sally, additional, Matsumoto, Takahiro, additional, Koshida, Iori, additional, Yoshimura, Kimihiro, additional, Mihara, Masatomo, additional, Naitou, Masanori, additional, Endoh, Hideki, additional, Nakamura, Takashi, additional, Akimoto, Chihiro, additional, Yamamoto, Yoko, additional, Katagiri, Takenobu, additional, Foulds, Charles, additional, Takezawa, Shinichiro, additional, Kitagawa, Hirochika, additional, Takeyama, Ken-ichi, additional, O'Malley, Bert W., additional, and Kato, Shigeaki, additional

Published
2007
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14. A cell cycle-dependent co-repressor mediates photoreceptor cell-specific nuclear receptor function

Author

Takezawa, Shinichiro, primary, Yokoyama, Atsushi, additional, Okada, Maiko, additional, Fujiki, Ryoji, additional, Iriyama, Aya, additional, Yanagi, Yasuo, additional, Ito, Hiroaki, additional, Takada, Ichiro, additional, Kishimoto, Masahiko, additional, Miyajima, Atsushi, additional, Takeyama, Ken-ichi, additional, Umesono, Kazuhiko, additional, Kitagawa, Hirochika, additional, and Kato, Shigeaki, additional

Published
2007
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17. TRRAP as a hepatic coactivator of LXR and FXR function

Author

Unno, Atsushi, primary, Takada, Ichiro, additional, Takezawa, Shinichiro, additional, Oishi, Hajime, additional, Baba, Atsushi, additional, Shimizu, Takafumi, additional, Tokita, Akifumi, additional, Yanagisawa, Junn, additional, and Kato, Shigeaki, additional

Published
2005
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18. Retraction: A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-γ transactivation.

Author

Takada, Ichiro, Mihara, Masatomo, Suzawa, Miyuki, Ohtake, Fumiaki, Kobayashi, Shinji, Igarashi, Mamoru, Youn, Min-Young, Takeyama, Ken-ichi, Nakamura, Takashi, Mezaki, Yoshihiro, Takezawa, Shinichiro, Yogiashi, Yoshiko, Kitagawa, Hirochika, Yamada, Gen, Takada, Shinji, Minami, Yasuhiro, Shibuya, Hiroshi, Matsumoto, Kunihiro, and Kato, Shigeaki

Subjects
HISTONE demethylases, ACTIVATION (Chemistry), WNT genes
Abstract

A correction to the article "A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-γ transactivation" that was published in the 2007 issue is presented.

Published
2014
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19. Retraction: DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs.

Author

Fukuda, Toru, Yamagata, Kaoru, Fujiyama, Sally, Matsumoto, Takahiro, Koshida, Iori, Yoshimura, Kimihiro, Mihara, Masatomo, Naitou, Masanori, Endoh, Hideki, Nakamura, Takashi, Akimoto, Chihiro, Yamamoto, Yoko, Katagiri, Takenobu, Foulds, Charles, Takezawa, Shinichiro, Kitagawa, Hirochika, Takeyama, Ken-ichi, O'Malley, Bert W., and Kato, Shigeaki

Subjects
DNA helicases, RIBONUCLEASES, MICRORNA
Abstract

A correction to the article "DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs" that was published in the 2007 issue is presented.

Published
2014
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20. A histone lysine methyltransferase activated by non-canonical Wnt signalling supresses PPAR-? transactivation.

Author

Takada, Ichiro, Mihara, Masatomo, Suzawa, Miyuki, Ohtake, Fumiaki, Kobayashi, Shinji, Igarashi, Mamoru, Youn, Min-Young, Takeyama, Ken-ichi, Nakamura, Takashi, Mezaki, Yoshihiro, Takezawa, Shinichiro, Yogiashi, Yoshiko, Kitagawa, Hirochika, Yamada, Gen, Takada, Shinji, Minami, Yasuhiro, Shibuya, Hiroshi, Matsumoto, Kunihiro, and Kato, Shigeaki

Subjects
PUBLISHED errata, HISTONES, METHYLTRANSFERASES
Abstract

A correction to the article, related to the activation of the histone lysine methyltransferase by non-canonical Wnt, that was published in the previous issue of the journal is presented.

Published
2012
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23. A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation.

Author

Takada I, Mihara M, Suzawa M, Ohtake F, Kobayashi S, Igarashi M, Youn MY, Takeyama K, Nakamura T, Mezaki Y, Takezawa S, Yogiashi Y, Kitagawa H, Yamada G, Takada S, Minami Y, Shibuya H, Matsumoto K, and Kato S

Subjects
Adipogenesis, Animals, Cells, Cultured, Core Binding Factor Alpha 1 Subunit metabolism, Down-Regulation, Genetic Vectors, Histone-Lysine N-Methyltransferase drug effects, Mice, Mice, Transgenic, Mutation, Osteogenesis, PPAR gamma drug effects, PPAR gamma genetics, Phosphorylation, Plasmids, Signal Transduction drug effects, Wnt Proteins genetics, Wnt Proteins pharmacology, Wnt-5a Protein, Histone-Lysine N-Methyltransferase metabolism, PPAR gamma metabolism, Signal Transduction physiology, Transcriptional Activation physiology, Wnt Proteins physiology
Abstract

Histone modifications induced by activated signalling cascades are crucial to cell-lineage decisions. Osteoblast and adipocyte differentiation from common mesenchymal stem cells is under transcriptional control by numerous factors. Although PPAR-gamma (peroxisome proliferator activated receptor-gamma) has been established as a prime inducer of adipogenesis, cellular signalling factors that determine cell lineage in bone marrow remain generally unknown. Here, we show that the non-canonical Wnt pathway through CaMKII-TAK1-TAB2-NLK transcriptionally represses PPAR-gamma transactivation and induces Runx2 expression, promoting osteoblastogenesis in preference to adipogenesis in bone marrow mesenchymal progenitors. Wnt-5a activates NLK (Nemo-like kinase), which in turn phosphorylates a histone methyltransferase, SETDB1 (SET domain bifurcated 1), leading to the formation of a co-repressor complex that inactivates PPAR-gamma function through histone H3-K9 methylation. These findings suggest that the non-canonical Wnt signalling pathway suppresses PPAR-gamma function through chromatin inactivation triggered by recruitment of a repressing histone methyltransferase, thus leading to an osteoblastic cell lineage from mesenchymal stem cells.

Published
2007
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