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6. Microbial Processes for the Conversion of CO2 und CO

Author

Weuster-Botz, Dirk, Takors, Ralf, Stefanakis, Alexandros, Series Editor, Nikolaou, Ioannis, Series Editor, Kirchherr, Julian, Editorial Board Member, Komilis, Dimitrios, Editorial Board Member, Pan, Shu Yuan, Editorial Board Member, Salomone, Roberta, Editorial Board Member, Kircher, Manfred, editor, and Schwarz, Thomas, editor

Published
2023
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24. Euler-Lagrangian Simulations: A Proper Tool for Predicting Cellular Performance in Industrial Scale Bioreactors

Author

Hajian, Christopher Sarkizi Shams, Zieringer, Julia, Takors, Ralf, Scheper, Thomas, Series Editor, Belkin, Shimshon, Editorial Board Member, Bley, Thomas, Editorial Board Member, Bohlmann, Jörg, Editorial Board Member, Gu, Man Bock, Editorial Board Member, Hu, Wei-Shou, Editorial Board Member, Mattiasson, Bo, Editorial Board Member, Olsson, Lisbeth, Editorial Board Member, Seitz, Harald, Editorial Board Member, Silva, Ana Catarina, Editorial Board Member, Ulber, Roland, Editorial Board Member, Zeng, An-Ping, Editorial Board Member, Zhong, Jian-Jiang, Editorial Board Member, Zhou, Weichang, Editorial Board Member, Herwig, Christoph, editor, Pörtner, Ralf, editor, and Möller, Johannes, editor

Published
2021
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30. Prozessmodelle

Author

Takors, Ralf, Weuster-Botz, Dirk, Chmiel, Horst, editor, Takors, Ralf, editor, Weuster-Botz, Dirk, editor, and Zettlmeier, Wolfgang, Illustrations by

Published
2018
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31. Wachstumskinetik

Author

Weuster-Botz, Dirk, Takors, Ralf, Chmiel, Horst, editor, Takors, Ralf, editor, Weuster-Botz, Dirk, editor, and Zettlmeier, Wolfgang, Illustrations by

Published
2018
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42. Optimizing Mass Transfer in Multiphase Fermentation: The Role of Drag Models and Physical Conditions.

Author

Mast, Yannic, Wild, Moritz, and Takors, Ralf

Subjects
MASS transfer coefficients, MASS transfer, FERMENTATION, COMPUTATIONAL fluid dynamics, MOTION, DIFFUSION coefficients, WATER power
Abstract

Detailed knowledge of the flow characteristics, bubble movement, and mass transfer is a prerequisite for the proper design of multiphase bioreactors. Often, mechanistic spatiotemporal models and computational fluid dynamics, which intrinsically require computationally demanding analysis of local interfacial forces, are applied. Typically, such approaches use volumetric mass-transfer coefficient (kLa) models, which have demonstrated their predictive power in water systems. However, are the related results transferrable to multiphase fermentations with different physicochemical properties? This is crucial for the proper design of biotechnological processes. Accordingly, this study investigated a given set of mass transfer data to characterize the fermentation conditions. To prevent time-consuming simulations, computational efforts were reduced using a force balance stationary 0-dimension model. Therefore, a competing set of drag models covering different mechanistic assumptions could be evaluated. The simplified approach of disregarding fluid movement provided reliable results and outlined the need to identify the liquid diffusion coefficients in fermentation media. To predict the rising bubble velocities uB, the models considering the Morton number (Mo) showed superiority. The mass transfer coefficient kL was best described using the well-known Higbie approach. Taken together, the gas hold-up, specific surface area, and integral mass transfer could be accurately predicted. [ABSTRACT FROM AUTHOR]

Published
2024
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