Search

Your search keyword '"Tamai, Hirofumi"' showing total 36 results
Start Over Author "Tamai, Hirofumi"
36 results on '"Tamai, Hirofumi"'

2. Deep learning analysis of clinical course of primary nephrotic syndrome: Japan Nephrotic Syndrome Cohort Study (JNSCS)

Author

Kimura, Tomonori, Yamamoto, Ryohei, Yoshino, Mitsuaki, Sakate, Ryuichi, Imai, Enyu, Maruyama, Shoichi, Yokoyama, Hitoshi, Sugiyama, Hitoshi, Nitta, Kosaku, Tsukamoto, Tatsuo, Uchida, Shunya, Takeda, Asami, Sato, Toshinobu, Wada, Takashi, Hayashi, Hiroki, Akai, Yasuhiro, Fukunaga, Megumu, Tsuruya, Kazuhiko, Masutani, Kosuke, Konta, Tsuneo, Shoji, Tatsuya, Hiramatsu, Takeyuki, Goto, Shunsuke, Tamai, Hirofumi, Nishio, Saori, Nagai, Kojiro, Yamagata, Kunihiro, Yasuda, Hideo, Ichida, Shizunori, Naruse, Tomohiko, Nishino, Tomoya, Sobajima, Hiroshi, Akahori, Toshiyuki, Ito, Takafumi, Terada, Yoshio, Katafuchi, Ritsuko, Fujimoto, Shouichi, Okada, Hirokazu, Mimura, Tetsushi, Suzuki, Satoshi, Saka, Yosuke, Sofue, Tadashi, Kitagawa, Kiyoki, Fujita, Yoshiro, Mizutani, Makoto, Kashihara, Naoki, Sato, Hiroshi, Narita, Ichiei, and Isaka, Yoshitaka

Published
2022
Full Text
View/download PDF

4. Time to remission of proteinuria and incidence of relapse in patients with steroid-sensitive minimal change disease and focal segmental glomerulosclerosis: the Japan Nephrotic Syndrome Cohort Study

Author

Yamamoto, Ryohei, Imai, Enyu, Maruyama, Shoichi, Yokoyama, Hitoshi, Sugiyama, Hitoshi, Takeda, Asami, Tsukamoto, Tatsuo, Uchida, Shunya, Tsuruya, Kazuhiko, Shoji, Tatsuya, Hayashi, Hiroki, Akai, Yasuhiro, Fukunaga, Megumu, Konta, Tsuneo, Nishio, Saori, Goto, Shunsuke, Tamai, Hirofumi, Nagai, Kojiro, Katafuchi, Ritsuko, Masutani, Kosuke, Wada, Takashi, Nishino, Tomoya, Shirasaki, Arimasa, Sobajima, Hiroshi, Nitta, Kosaku, Yamagata, Kunihiro, Kazama, Junichiro J., Hiromura, Keiju, Yasuda, Hideo, Mizutani, Makoto, Akahori, Toshiyuki, Naruse, Tomohiko, Hiramatsu, Takeyuki, Morozumi, Kunio, Mimura, Tetsushi, Saka, Yosuke, Ishimura, Eiji, Hasegawa, Hajime, Ichikawa, Daisuke, Shigematsu, Takashi, Sato, Hiroshi, Narita, Ichiei, and Isaka, Yoshitaka

Published
2022
Full Text
View/download PDF

6. Predictors of early remission of proteinuria in adult patients with minimal change disease: a retrospective cohort study

Author

Yamamoto, Ryohei, Imai, Enyu, Maruyama, Shoichi, Yokoyama, Hitoshi, Sugiyama, Hitoshi, Takeda, Asami, Uchida, Shunya, Tsukamoto, Tatsuo, Tsuruya, Kazuhiko, Akai, Yasuhiro, Nitta, Kosaku, Fukunaga, Megumu, Hayashi, Hiroki, Masutani, Kosuke, Wada, Takashi, Konta, Tsuneo, Katafuchi, Ritsuko, Nishio, Saori, Goto, Shunsuke, Tamai, Hirofumi, Shirasaki, Arimasa, Shoji, Tatsuya, Nagai, Kojiro, Nishino, Tomoya, Yamagata, Kunihiro, Kazama, Junichiro J., Hiromura, Keiju, Yasuda, Hideo, Mizutani, Makoto, Naruse, Tomohiko, Hiramatsu, Takeyuki, Morozumi, Kunio, Sobajima, Hiroshi, Saka, Yosuke, Ishimura, Eiji, Ichikawa, Daisuke, Shigematsu, Takashi, Sofue, Tadashi, Fujimoto, Shouichi, Ito, Takafumi, Sato, Hiroshi, Narita, Ichiei, and Isaka, Yoshitaka

Published
2022
Full Text
View/download PDF

7. Better remission rates in elderly Japanese patients with primary membranous nephropathy in nationwide real-world practice: The Japan Nephrotic Syndrome Cohort Study (JNSCS)

Author

Yokoyama, Hitoshi, Yamamoto, Ryohei, Imai, Enyu, Maruyama, Shoichi, Sugiyama, Hitoshi, Nitta, Kosaku, Tsukamoto, Tatsuo, Uchida, Shunya, Takeda, Asami, Sato, Toshinobu, Wada, Takashi, Hayashi, Hiroki, Akai, Yasuhiro, Fukunaga, Megumu, Tsuruya, Kazuhiko, Masutani, Kosuke, Konta, Tsuneo, Shoji, Tatsuya, Hiramatsu, Takeyuki, Goto, Shunsuke, Tamai, Hirofumi, Nishio, Saori, Shirasaki, Arimasa, Nagai, Kojiro, Yamagata, Kunihiro, Hasegawa, Hajime, Yasuda, Hidemo, Ichida, Shizunori, Naruse, Tomohiko, Fukami, Kei, Nishino, Tomoya, Sobajima, Hiroshi, Tanaka, Satoshi, Akahori, Toshiyuki, Ito, Takafumi, Terada, Yoshio, Katafuchi, Ritsuko, Fujimoto, Shouichi, Okada, Hirokazu, Ishimura, Eiji, Kazama, Junichiro James, Hiromura, Keiju, Mimura, Tetsushi, Suzuki, Satashi, Saka, Yosuke, Sofue, Tadashi, Suzuki, Yusuke, Shibagaki, Yugo, Kitagawa, Kiyoki, Morozumi, Kunio, Fujita, Yoshiro, Mizutani, Makoto, Shigematsu, Takashi, Furuichi, Kengo, Fujimoto, Keiji, Kashihara, Naoki, Sato, Hiroshi, Matsuo, Seiichi, Narita, Ichiei, and Isaka, Yoshitaka

Published
2020
Full Text
View/download PDF

8. Incidence of remission and relapse of proteinuria, end-stage kidney disease, mortality, and major outcomes in primary nephrotic syndrome: the Japan Nephrotic Syndrome Cohort Study (JNSCS)

Author

Yamamoto, Ryohei, Imai, Enyu, Maruyama, Shoichi, Yokoyama, Hitoshi, Sugiyama, Hitoshi, Nitta, Kosaku, Tsukamoto, Tatsuo, Uchida, Shunya, Takeda, Asami, Sato, Toshinobu, Wada, Takashi, Hayashi, Hiroki, Akai, Yasuhiro, Fukunaga, Megumu, Tsuruya, Kazuhiko, Masutani, Kosuke, Konta, Tsuneo, Shoji, Tatsuya, Hiramatsu, Takeyuki, Goto, Shunsuke, Tamai, Hirofumi, Nishio, Saori, Shirasaki, Arimasa, Nagai, Kojiro, Yamagata, Kunihiro, Hasegawa, Hajime, Yasuda, Hideo, Ichida, Shizunori, Naruse, Tomohiko, Nishino, Tomoya, Sobajima, Hiroshi, Tanaka, Satoshi, Akahori, Toshiyuki, Ito, Takafumi, Terada, Yoshio, Katafuchi, Ritsuko, Fujimoto, Shouichi, Okada, Hirokazu, Ishimura, Eiji, Kazama, Junichiro J., Hiromura, Keiju, Mimura, Tetsushi, Suzuki, Satoshi, Saka, Yosuke, Sofue, Tadashi, Suzuki, Yusuke, Shibagaki, Yugo, Kitagawa, Kiyoki, Morozumi, Kunio, Fujita, Yoshiro, Mizutani, Makoto, Shigematsu, Takashi, Kashihara, Naoki, Sato, Hiroshi, Matsuo, Seiichi, Narita, Ichiei, and Isaka, Yoshitaka

Published
2020
Full Text
View/download PDF

9. Rationale and design of the Japanese Biomarkers in Nephrotic Syndrome (J-MARINE) study.

Author

Kurasawa, Shimon, Kato, Sawako, Ozeki, Takaya, Akiyama, Shin'ichi, Ishimoto, Takuji, Mizuno, Masashi, Tsuboi, Naotake, Kato, Noritoshi, Kosugi, Tomoki, Maruyama, Shoichi, Tamai, Hirofumi, Takeda, Asami, Shinjo, Hibiki, Arata, Hanayo, Naruse, Tomohiko, Watanabe, Tomoharu, Hiromura, Keiju, Fukami, Kei, Nakagawa, Naoki, and Akahori, Toshiyuki

Subjects
NEPHROTIC syndrome, BIOMARKERS, PLASMINOGEN activators, JAPANESE people, FOCAL segmental glomerulosclerosis, GLOMERULAR filtration rate
Abstract

Introduction: Disease subtyping and monitoring are essential for the management of nephrotic syndrome (NS). Although various biomarkers for NS have been reported, their clinical efficacy has not been comprehensively validated in adult Japanese patients. Methods: The Japanese Biomarkers in Nephrotic Syndrome (J-MARINE) study is a nationwide, multicenter, and prospective cohort study in Japan, enrolling adult (≥18 years) patients with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), membranoproliferative glomerulonephritis (MPGN), C3 glomerulopathy (C3G), and lupus nephritis (LN). Baseline clinical information and plasma and urine samples will be collected at the time of immunosuppressive therapy initiation or biopsy. Follow-up data and plasma and urine samples will be collected longitudinally based on the designated protocols. Candidate biomarkers will be measured: CD80, cytotoxic T-lymphocyte antigen 4, and soluble urokinase plasminogen activator receptor for MCD and FSGS; anti-phospholipase A2 receptor and thrombospondin type-1 domain-containing protein 7A antibodies for MN; fragment Ba, C3a, factor I, and properdin for MPGN/C3G; and CD11b, CD16b, and CD163 for LN. Outcomes include complete and partial remission, relapse of proteinuria, a 30% reduction in estimated glomerular filtration rate (eGFR), eGFR decline, and initiation of renal replacement therapy. The diagnostic accuracy and predictive ability for clinical outcomes will be assessed for each biomarker. Results: From April 2019 to April 2023, 365 patients were enrolled: 145, 21, 138, 10, and 51 cases of MCD, FSGS, MN, MPGN/C3G, and LN, respectively. Conclusion: This study will provide valuable insights into biomarkers for NS and serve as a biorepository for future studies. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

10. Febuxostat Therapy for Patients With Stage 3 CKD and Asymptomatic Hyperuricemia: A Randomized Trial

Author

Kimura, Kenjiro, Hosoya, Tatsuo, Ito, Sadayoshi, Inaba, Masaaki, Tomino, Yasuhiko, Uchida, Shunya, Makino, Hirofumi, Matsuo, Seiichi, Yamanaka, Hisashi, Yamamoto, Tetsuya, Ohno, Iwao, Shibagaki, Yugo, Iimuro, Satoshi, Imai, Naohiko, Kuwabara, Masanari, Hayakawa, Hiroshi, Akizawa, Tadao, Teramoto, Tamio, Kasanuki, Hiroshi, Yoshimura, Kenichi, Sato, Hiroshi, Horikoshi, Satoshi, Maruyama, Syoichi, Inaba, Masahiko, Moriwaki, Yuji, Uchida, Haruhito, Kaneshiro, Nagayuki, Moriya, Hidekazu, Komatsu, Yasuhiro, Kaname, Shinya, Hanaoka, Kazunari, Ogura, Makoto, Ikeda, Masato, Kasai, Kenji, Sugiura, Akira, Takahashi, Kazushi, Kojima, Kenichiro, Nitta, Kosaku, Tamai, Hirofumi, Nagaya, Hiroshi, Okuno, Senji, Kakiya, Ryusuke, Takeoka, Hiroya, Hirata, Kyouji, Asano, Kenichiro, Fukaya, Yasuo, Iwaida, Yasushi, Tsuneda, Yasuo, Nishimura, Shigeaki, Hiramatsu, Takeyuki, Isaka, Yoshitaka, Ito, Takafumi, Yuzawa, Yukio, Yamagata, Kunihiro, Sofue, Tadashi, Jinguji, Yoshimi, Hirano, Keita, Matsuyama, Kazuhiro, Mizumoto, Teruhiko, Shibuya, Yuko, Sugawara, Masahiro, Kadomura, Moritoshi, Teshima, Yasuaki, Ohtani, Hiroshi, Kamata, Hiroki, Okawara, Susumu, Fukushima, Masaki, Takemura, Katsumi, Kinugasa, Eriko, Kogure, Masami, Ehara, Yoichi, Maruyama, Shoichi, Ohtsu, Hiroshi, and Ohashi, Yasuo

Published
2018
Full Text
View/download PDF

11. Regional variations in immunosuppressive therapy in patients with primary nephrotic syndrome: the Japan nephrotic syndrome cohort study

Author

Yamamoto, Ryohei, Imai, Enyu, Maruyama, Shoichi, Yokoyama, Hitoshi, Sugiyama, Hitoshi, Nitta, Kosaku, Tsukamoto, Tatsuo, Uchida, Shunya, Takeda, Asami, Sato, Toshinobu, Wada, Takashi, Hayashi, Hiroki, Akai, Yasuhiro, Fukunaga, Megumu, Tsuruya, Kazuhiko, Masutani, Kosuke, Konta, Tsuneo, Shoji, Tatsuya, Hiramatsu, Takeyuki, Goto, Shunsuke, Tamai, Hirofumi, Nishio, Saori, Shirasaki, Arimasa, Nagai, Kojiro, Yamagata, Kunihiro, Hasegawa, Hajime, Yasuda, Hidemo, Ichida, Shizunori, Naruse, Tomohiko, Fukami, Kei, Nishino, Tomoya, Sobajima, Hiroshi, Tanaka, Satoshi, Akahori, Toshiyuki, Ito, Takafumi, Yoshio, Terada, Katafuchi, Ritsuko, Fujimoto, Shouichi, Okada, Hirokazu, Ishimura, Eiji, Kazama, Junichiro James, Hiromura, Keiju, Mimura, Tetsushi, Suzuki, Satashi, Saka, Yosuke, Sofue, Tadashi, Suzuki, Yusuke, Shibagaki, Yugo, Kitagawa, Kiyoki, Morozumi, Kunio, Fujita, Yoshiro, Mizutani, Makoto, Shigematsu, Takashi, Kashihara, Naoki, Sato, Hiroshi, Matsuo, Seiichi, Narita, Ichiei, and Isaka, Yoshitaka

Published
2018
Full Text
View/download PDF

13. Higher hemoglobin levels using darbepoetin alfa and kidney outcomes in advanced chronic kidney disease without diabetes: a prespecified secondary analysis of the PREDICT trial.

Author

Maruyama, Shoichi, Kurasawa, Shimon, Hayashi, Terumasa, Nangaku, Masaomi, Narita, Ichiei, Hirakata, Hideki, Tanabe, Kenichiro, Morita, Satoshi, Tsubakihara, Yoshiharu, Imai, Enyu, Akizawa, Tadao, PREDICT Investigators, Hiramatsu, Takeyuki, Tamai, Hirofumi, Iida, Yoshiyasu, Naruse, Tomohiro, Oishi, Hideto, Uchida, Shunya, Shimizu, Hideaki, and Morozumi, Kunio

Subjects
CHRONIC kidney failure, HEMOGLOBINS, SECONDARY analysis, GLOMERULAR filtration rate, KIDNEYS
Abstract

Background: In the primary analysis of the PREDICT trial, a higher hemoglobin target (11–13 g/dl) with darbepoetin alfa did not improve renal outcomes compared with a lower hemoglobin target (9–11 g/dl) in advanced chronic kidney disease (CKD) without diabetes. Prespecified secondary analyses were performed to further study the effects of targeting higher hemoglobin levels on renal outcomes. Methods: Patients with an estimated glomerular filtration rate (eGFR) 8–20 ml/min/1.73 m2 without diabetes were randomly assigned 1:1 to the high- and low-hemoglobin groups. The differences between the groups were evaluated for the following endpoints and cohort sets: eGFR and proteinuria slopes, assessed using a mixed-effects model in the full analysis set and the per-protocol set that excluded patients with off-target hemoglobin levels; the primary endpoint of composite renal outcome, evaluated in the per-protocol set using the Cox model. Results: In the full analysis set (high hemoglobin, n = 239; low hemoglobin, n = 240), eGFR and proteinuria slopes were not significantly different between the groups. In the per-protocol set (high hemoglobin, n = 136; low hemoglobin, n = 171), the high-hemoglobin group was associated with reduced composite renal outcome (adjusted hazard ratio: 0.64; 95% confidence interval: 0.43–0.96) and an improved eGFR slope (coefficient: + 1.00 ml/min/1.73 m2/year; 95% confidence interval: 0.38–1.63), while the proteinuria slope did not differ between the groups. Conclusions: In the per-protocol set, the high-hemoglobin group demonstrated better kidney outcomes than the low-hemoglobin group, suggesting a potential benefit of maintaining higher hemoglobin levels in patients with advanced CKD without diabetes. Clinical trial registration: Clinicaltrials.gov (identifier: NCT01581073). [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

14. Recent analysis of status and outcomes of peritoneal dialysis in the Tokai area of Japan: the second report of the Tokai peritoneal dialysis registry

Author

Mizuno, Masashi, Ito, Yasuhiko, Suzuki, Yasuhiro, Sakata, Fumiko, Saka, Yosuke, Hiramatsu, Takeyuki, Tamai, Hirofumi, Mizutani, Makoto, Naruse, Tomohiko, Ohashi, Norimi, Kasuga, Hirotake, Shimizu, Hideaki, Kurata, Hisashi, Kurata, Kei, Suzuki, Satoshi, Kido, Satoko, Tsuruta, Yoshikazu, Matsuoka, Teppei, Horie, Masanobu, Maruyama, Shoichi, and Matsuo, Seiichi

Published
2016
Full Text
View/download PDF

16. Acute Kidney Injury and Remission of Proteinuria in Minimal Change Disease

Author

Yamamoto, Ryohei, primary, Imai, Enyu, additional, Maruyama, Shoichi, additional, Yokoyama, Hitoshi, additional, Sugiyama, Hitoshi, additional, Takeda, Asami, additional, Uchida, Shunya, additional, Tsukamoto, Tatsuo, additional, Tsuruya, Kazuhiko, additional, Akai, Yasuhiro, additional, Nitta, Kosaku, additional, Fukunaga, Megumu, additional, Hayashi, Hiroki, additional, Shoji, Tatsuya, additional, Masutani, Kosuke, additional, Konta, Tsuneo, additional, Katafuchi, Ritsuko, additional, Nishio, Saori, additional, Wada, Takashi, additional, Goto, Shunsuke, additional, Tamai, Hirofumi, additional, Shirasaki, Arimasa, additional, Nagai, Kojiro, additional, Nishino, Tomoya, additional, Yamagata, Kunihiro, additional, Kazama, Junichiro J., additional, Hiromura, Keiju, additional, Yasuda, Hideo, additional, Sofue, Tadashi, additional, Fujimoto, Shouichi, additional, Mizutani, Makoto, additional, Naruse, Tomohiko, additional, Hiramatsu, Takeyuki, additional, Morozumi, Kunio, additional, Sobajima, Hiroshi, additional, Saka, Yosuke, additional, Ishimura, Eiji, additional, Ito, Takafumi, additional, Ichikawa, Daisuke, additional, Shigematsu, Takashi, additional, Sato, Hiroshi, additional, Narita, Ichiei, additional, and Yoshitaka, Isaka, additional

Published
2022
Full Text
View/download PDF

18. The effectiveness and safety of computed tomographic peritoneography and video-assisted thoracic surgery for hydrothorax in peritoneal dialysis patients: A retrospective cohort study in Japan

Author

Matsuoka, Naoya, primary, Yamaguchi, Makoto, additional, Asai, Akimasa, additional, Kamiya, Keisuke, additional, Kinashi, Hiroshi, additional, Katsuno, Takayuki, additional, Kobayashi, Takaaki, additional, Tamai, Hirofumi, additional, Morinaga, Takatoshi, additional, Obayashi, Takaaki, additional, Nakabayashi, Kichio, additional, Koide, Shigehisa, additional, Nakanishi, Michimasa, additional, Koyama, Katsushi, additional, Suzuki, Yasuhiro, additional, Ishimoto, Takuji, additional, Mizuno, Masashi, additional, and Ito, Yasuhiko, additional

Published
2020
Full Text
View/download PDF

20. Incidence of remission and relapse of proteinuria, end-stage kidney disease, mortality, and major outcomes in primary nephrotic syndrome: the Japan Nephrotic Syndrome Cohort Study (JNSCS)

Author

Yamamoto , Ryohei, Imai , Enyu, Maruyama, Shoichi, Yokoyama, Hitoshi, Sugiyama, Hitoshi, Nitta, Kosaku, Tsukamoto , Tatsuo, Uchida , Shunya, Takeda, Asami, Sato, Toshinobu, Wada, Takashi, Hayashi, Hiroki, Akai, Yasuhiro, Fukunaga, Megumu, Tsuruya, Kazuhiko, Masutani , Kosuke, Konta, Tsuneo, Shoji, Tatsuya, Hiramatsu, Takeyuki, Goto, Shunsuke, Tamai, Hirofumi, Nishio, Saori, Shirasaki , Arimasa, Nagai, Kojiro, Yamagata, Kunihiro, Hasegawa, Hajime, Yasuda, Hideo, Ichida, Shizunori, Naruse, Tomohiko, Nishino, Tomoya, Sobajima, Hiroshi, Tanaka, Satoshi, Akahori, Toshiyuki, ITO, Takafumi, Terada, Yoshio, Katafuchi, Ritsuko, Fujimoto, Shouichi, Okada, Hirokazu, Shimura, Eiji, Kazama, Junichiro J., Hiromura, Keiju, Mimura, Tetsushi, Suzuki, Satoshi, Saka, Yosuke, Sofue, Tadashi, Suzuki , Yusuke, Shibagaki , Yugo, Kitagawa , Kiyoki, Morozumi , Kunio, Fujita , Yoshiro, Mizutani , Makoto, Shigematsu , Takashi, Kashihara , Naoki, Sato , Hiroshi, Matsuo , Seiichi, Narita , Ichiei, Isaka , Yoshitaka, Yamamoto , Ryohei, Imai , Enyu, Maruyama, Shoichi, Yokoyama, Hitoshi, Sugiyama, Hitoshi, Nitta, Kosaku, Tsukamoto , Tatsuo, Uchida , Shunya, Takeda, Asami, Sato, Toshinobu, Wada, Takashi, Hayashi, Hiroki, Akai, Yasuhiro, Fukunaga, Megumu, Tsuruya, Kazuhiko, Masutani , Kosuke, Konta, Tsuneo, Shoji, Tatsuya, Hiramatsu, Takeyuki, Goto, Shunsuke, Tamai, Hirofumi, Nishio, Saori, Shirasaki , Arimasa, Nagai, Kojiro, Yamagata, Kunihiro, Hasegawa, Hajime, Yasuda, Hideo, Ichida, Shizunori, Naruse, Tomohiko, Nishino, Tomoya, Sobajima, Hiroshi, Tanaka, Satoshi, Akahori, Toshiyuki, ITO, Takafumi, Terada, Yoshio, Katafuchi, Ritsuko, Fujimoto, Shouichi, Okada, Hirokazu, Shimura, Eiji, Kazama, Junichiro J., Hiromura, Keiju, Mimura, Tetsushi, Suzuki, Satoshi, Saka, Yosuke, Sofue, Tadashi, Suzuki , Yusuke, Shibagaki , Yugo, Kitagawa , Kiyoki, Morozumi , Kunio, Fujita , Yoshiro, Mizutani , Makoto, Shigematsu , Takashi, Kashihara , Naoki, Sato , Hiroshi, Matsuo , Seiichi, Narita , Ichiei, and Isaka , Yoshitaka

Published
2020

22. Effects of Sustained‐Release Beraprost in Patients With Primary Glomerular Disease or Nephrosclerosis: CASSIOPEIR Study Results

Author

Nakamoto, Hidetomo, primary, Yu, Xue‐Qing, additional, Kim, Suhnggwon, additional, Origasa, Hideki, additional, Zheng, Hongguang, additional, Chen, Jianghua, additional, Joo, Kwon Wook, additional, Sritippayawan, Suchai, additional, Chen, Qinkai, additional, Chen, Hung‐Chun, additional, Tsubakihara, Yoshiharu, additional, Tamai, Hirofumi, additional, Song, Sang Heon, additional, Vaithilingam, Indralingam, additional, Lee, Kang Wook, additional, Shu, Kuo‐Hsiung, additional, Hok‐King Lo, Stanley, additional, Isono, Masanao, additional, Kurumatani, Hajimu, additional, Okada, Kiyonobu, additional, Kanoh, Hiroyuki, additional, Kiriyama, Takashi, additional, Yamada, Shunsuke, additional, and Fujita, Toshiro, additional

Published
2019
Full Text
View/download PDF

25. Effects of Sustained‐Release Beraprost in Patients With Primary Glomerular Disease or Nephrosclerosis: CASSIOPEIR Study Results.

Author

Nakamoto, Hidetomo, Yu, Xue‐Qing, Kim, Suhnggwon, Origasa, Hideki, Zheng, Hongguang, Chen, Jianghua, Joo, Kwon Wook, Sritippayawan, Suchai, Chen, Qinkai, Chen, Hung‐Chun, Tsubakihara, Yoshiharu, Tamai, Hirofumi, Song, Sang Heon, Vaithilingam, Indralingam, Lee, Kang Wook, Shu, Kuo‐Hsiung, Hok‐King Lo, Stanley, Isono, Masanao, Kurumatani, Hajimu, and Okada, Kiyonobu

Subjects
DRUG side effects, CHRONIC kidney failure, CONTROLLED release preparations, KIDNEY glomerulus diseases, CHRONICALLY ill, ADVERSE health care events
Abstract

TRK‐100STP, a sustained‐release preparation of the orally active prostacyclin analogue beraprost sodium, targets renal hypoxia. This study aimed to show the superiority of TRK‐100STP over placebos in patients with chronic kidney disease (with either primary glomerular disease or nephrosclerosis) to determine the recommended dose. CASSIOPEIR (Chronic Renal Failure Asian Study with Oral PGI2 Derivative for Evaluating Improvement of Renal Function) was a randomized, double‐blind, placebo‐controlled study conducted at 160 sites in seven Asia‐Pacific countries and regions. Eligible patients (n = 892) were randomized to TRK‐100STP 120, 240 μg, or placebo for a treatment period of up to 4 years. The primary efficacy endpoint was time to first occurrence of a renal composite: doubling of serum creatinine or occurrence of end‐stage renal disease. No significant differences were observed in composite endpoints between TRK‐100STP and placebo (P = 0.5674). Hazard ratios (95% CI) in the TRK‐100STP 120 and 240 μg vs. placebo groups were 0.98 (0.78, 1.22) and 0.91 (0.72, 1.14), respectively. The overall incidence of adverse events and adverse drug reactions was comparable between treatment arms. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

26. Two brothers with collagenofibrotic glomerulopathy

Author

Aoki, Takafumi, primary, Hayashi, Kazuyuki, additional, Morinaga, Takatoshi, additional, Tomida, Hidetaka, additional, Hishida, Manabu, additional, Yamamoto, Satoko, additional, Kajiwara, Nobuyuki, additional, and Tamai, Hirofumi, additional

Published
2014
Full Text
View/download PDF

27. Long-Term Effects of Spironolactone in Peritoneal Dialysis Patients

Author

Ito, Yasuhiko, primary, Mizuno, Masashi, additional, Suzuki, Yasuhiro, additional, Tamai, Hirofumi, additional, Hiramatsu, Takeyuki, additional, Ohashi, Hiroshige, additional, Ito, Isao, additional, Kasuga, Hirotake, additional, Horie, Masanobu, additional, Maruyama, Shoichi, additional, Yuzawa, Yukio, additional, Matsubara, Tatsuaki, additional, and Matsuo, Seiichi, additional

Published
2014
Full Text
View/download PDF

33. Emphysematous pyelonephritis complicated by liver cirrhosis and diabetes mellitus: a case report and a review of the literature

Author

ITOH, Kohichi, TAMAI, Hirofumi, ARISAWA, Tomiyasu, KUMON, Shinichi, and YAMADA, Yoshiaki

Subjects
Emphysematous pyelonephritis, A case report, 494.9
Abstract

A case of emphysematous pyelonephritis is presented and a review of literatures is made. A 67-years-old woman with diabetes mellitus, complained of severe left flank pain and high fever and was referred from the department of gastroenterology. A computed tomography film demonstrated gas in the left renal parenchyma and a diagnosis of emphysematous pyelonephritis was made. She was in a state of shock and died after 4 days of conservative treatment. Emphysematous pyelonephritis is a rare, life-threatening disorder and 85 cases in the world have been reported to date. Our case is the 18th one in Japan. Its etiology, symptomatology, treatment and prognosis are discussed.

Published
1987

34. This title is unavailable for guests, please login to see more information.

Author

ITOH, Kohichi, TAMAI, Hirofumi, ARISAWA, Tomiyasu, KUMON, Shinichi, YAMADA, Yoshiaki, ITOH, Kohichi, TAMAI, Hirofumi, ARISAWA, Tomiyasu, KUMON, Shinichi, and YAMADA, Yoshiaki

Abstract

A case of emphysematous pyelonephritis is presented and a review of literatures is made. A 67-years-old woman with diabetes mellitus, complained of severe left flank pain and high fever and was referred from the department of gastroenterology. A computed tomography film demonstrated gas in the left renal parenchyma and a diagnosis of emphysematous pyelonephritis was made. She was in a state of shock and died after 4 days of conservative treatment. Emphysematous pyelonephritis is a rare, life-threatening disorder and 85 cases in the world have been reported to date. Our case is the 18th one in Japan. Its etiology, symptomatology, treatment and prognosis are discussed.

Published
1987

Catalog

Books, media, physical & digital resources
See catalog results