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288 results on '"Tan, Benjamin Yong-Qiang"'

13. Effects of Sodium/Glucose Cotransporter Inhibitors on Atrial Fibrillation and Stroke: A Meta-Analysis

Author

Ong, How Ting, Teo, Yao Hao, Teo, Yao Neng, Syn, Nicholas LX, Wee, Caitlin Fern, Leong, Shariel, Yip, Alicia Swee Yan, See, Ray Meng, Ting, Adriel Zhi Hen, Chia, Alys ZQ, Cheong, Alex Jia Yang, Tan, Benjamin Yong-Qiang, Ho, Jamie Sin-Ying, Yeo, Leonard Leong-Litt, Leow, Aloysius Sheng-Ting, Yeo, Tiong-Cheng, Wong, Raymond CC, Chai, Ping, Kojodjojo, Pipin, and Sia, Ching-Hui

Published
2022
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16. Hospital-based observational study of neurological disorders in patients recently vaccinated with COVID-19 mRNA vaccines

Author

Koh, Jasmine Shimin, Hoe, Rebecca Hui Min, Yong, Ming Hui, Chiew, Hui Jin, Goh, Yihui, Yong, Kok Pin, Tu, Tian Ming, Chan, Derrick Wei Shih, Tan, Benjamin Yong-Qiang, Yeo, Leonard Leong Litt, Quek, Amy May Lin, Siow, Isabel, Saini, Monica, Angon, Jasmyn, Rathakrishnan, Sharmini, Chen, Geraldine Jiangyan, Hui, Andrew Che-Fai, Ahmad, Aftab, Shwe, Moe Pearl, Tan, Kevin, Seet, Raymond Chee Seong, Cai, Mingshi, Kuo, Si Min, Foo, Ling Li, and Umapathi, Thirugnanam

Published
2021
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23. Neurology of COVID-19 in Singapore

Author

Koh, Jasmine Shimin, De Silva, Deidre Anne, Quek, Amy May Lin, Chiew, Hui Jin, Tu, Tian Ming, Seet, Christopher Ying Hao, Hoe, Rebecca Hui Min, Saini, Monica, Hui, Andrew Che-Fai, Angon, Jasmyn, Ker, Justin Ruixin, Yong, Ming Hui, Goh, Yihui, Yu, Wai-Yung, Lim, Tchoyoson Choie Cheio, Tan, Benjamin Yong Qiang, Ng, Kay Wei Ping, Yeo, Leonard Leong Litt, Pang, Yu Zhi, Prakash, Kumar M., Ahmad, Aftab, Thomas, Terrence, Lye, David Chien Boon, Tan, Kevin, and Umapathi, Thirugnanam

Published
2020
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27. Migraine and atrial fibrillation: a systematic review and meta-analysis

Author

Lim, Camelia Qi En, primary, Teo, Yao Neng, additional, Li, Tony Yi-Wei, additional, Teo, Yao Hao, additional, Syn, Nicholas Li-Xun, additional, Leow, Aloysius Sheng-Ting, additional, Ho, Jamie Sin-Ying, additional, Lim, Toon Wei, additional, Seow, Swee-Chong, additional, Chan, Mark Yan Yee, additional, Wong, Raymond Ching Chiew, additional, Chai, Ping, additional, Chan, Amanda Chee Yun, additional, Sharma, Vijay Kumar, additional, Tan, Benjamin Yong-Qiang, additional, Yeo, Leonard Leong Litt, additional, Ong, Jonathan Jia Yuan, additional, and Sia, Ching-Hui, additional

Published
2024
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30. Revolutionizing the Management of Large-Core Ischaemic Strokes: Decoding the Success of Endovascular Therapy in the Recent Stroke Trials

Author

Lim, Gareth Zigui, primary, Lai, Jonathan Yexian, additional, Seet, Christopher Ying Hao, additional, Tham, Carol Huilian, additional, Venketasubramanian, Narayanaswamy, additional, Tan, Benjamin Yong Qiang, additional, Jing, Mingxue, additional, Yeo, Joshua Yee Peng, additional, Myint, May Zin, additional, Sia, Ching-Hui, additional, Teoh, Hock Luen, additional, Sharma, Vijay Kumar, additional, Chan, Bernard, additional, Yang, Cunli, additional, Makmur, Andrew, additional, Ong, Shao Jin, additional, and Leong, Leonard Litt Yeo, additional

Published
2023
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32. Thrombectomy in Extensive Stroke May Not Be Beneficial and Is Associated With Increased Risk for Hemorrhage

Author

Meyer, Lukas, Bechstein, Matthias, Bester, Maxim, Hanning, Uta, Brekenfeld, Caspar, Flottmann, Fabian, Kniep, Helge, van Horn, Noel, Deb-Chatterji, Milani, Thomalla, Götz, Sporns, Peter, Yeo, Leonard Leong-Litt, Tan, Benjamin Yong-Qiang, Gopinathan, Anil, Kastrup, Andreas, Politi, Maria, Papanagiotou, Panagiotis, Kemmling, André, Fiehler, Jens, and Broocks, Gabriel

Published
2021
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41. Ambient Air Pollution and Acute Ischemic Stroke-Effect Modification by Atrial Fibrillation

Author

Tan, Benjamin Yong-Qiang, Ho, Jamie Sin Ying, Ho, Andrew Fu-Wah, Pek, Pin Pin, Leow, Aloysius Sheng-Ting, Raju, Yogeswari, Sia, Ching-Hui, Yeo, Leonard Leong-Litt, Sharma, Vijay Kumar, Ong, Marcus Eng-Hock, Aik, Joel, Zheng, Huili, Tan, Benjamin Yong-Qiang [0000-0003-1824-9077], Ho, Andrew Fu-Wah [0000-0003-4338-3876], Raju, Yogeswari [0000-0002-5927-5012], Sia, Ching-Hui [0000-0002-2764-2869], Sharma, Vijay Kumar [0000-0002-8976-5696], Ong, Marcus Eng-Hock [0000-0001-7874-7612], Aik, Joel [0000-0002-2851-9424], Zheng, Huili [0000-0002-3976-0088], and Apollo - University of Cambridge Repository

Subjects
air pollution, ischemic stroke, atrial fibrillation, cerebrovascular accident, environmental epidemiology
Abstract

Acute ischemic strokes (AIS) are closely linked with air pollution, and there is some evidence that traditional cardiovascular risk factors may alter the relationship between air pollution and strokes. We investigated the effect of atrial fibrillation (AF) on the association of AIS with air pollutants. This was a nationwide, population-based, case-only study that included all AIS treated in public healthcare institutions in Singapore from 2009 to 2018. Using multivariable logistic regression, adjusted for time-varying meteorological effects, we examined how AF modified the association between AIS and air pollutant exposure. A total of 51,673 episodes of AIS were included, with 10,722 (20.7%) having AF. The odds of AIS in patients with AF is higher than those without AF for every 1 µg/m3 increase in O3 concentration (adjusted OR [aOR]: 1.005, 95% CI 1.003-1.007) and every 1 mg/m3 increase in CO concentration (aOR: 1.193, 95% CI 1.050-1.356). However, the odds of AIS in patients with AF is lower than those without AF for every 1 µg/m3 increase in SO2 concentration (aOR: 0.993, 95% CI 0.990-0.997). Higher odds of AIS among AF patients as O3- and CO concentrations increase are also observed in patients aged ≥65 years and non-smokers. The results suggest that AF plays an important role in exacerbating the risk of AIS as the levels of O3 and CO increase.

Published
2022
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42. Stress and burnout amongst mental health professionals in Singapore during Covid-19 endemicity.

Author

Yang, Suyi, Tan, Germaine Ke Jia, Sim, Kang, Lim, Lucas Jun Hao, Tan, Benjamin Yong Qiang, Kanneganti, Abhiram, Ooi, Shirley Beng Suat, and Ong, Lue Ping

Subjects
PSYCHOLOGICAL burnout, MENTAL health personnel, COVID-19 pandemic, PSYCHIATRIC hospitals, FLEXIBLE work arrangements, PERCEIVED Stress Scale, ENDEMIC diseases
Abstract

The COVID-19 pandemic has exerted a huge emotional strain on mental health professionals (MHP) in Singapore. As Singapore transited into an endemic status, it is unclear whether the psychological strain has likewise lessened. The aims of this study were to investigate the levels of stress and burnout experienced by MHP working in a tertiary psychiatric hospital in Singapore during this phase of COVID-19 endemicity (2022) in comparison to the earlier pandemic years (2020 and 2021) and to identify factors which contribute to as well as ameliorate stress and burnout. A total of 282 MHP participated in an online survey in 2022, which included 2 validated measures, namely the Perceived Stress Scale and the Oldenburg Burnout Inventory (OLBI). Participants were also asked to rank factors that contributed the most to their stress and burnout. Between-group comparisons were conducted regarding stress and burnout levels among MHP across different demographic groupings and working contexts. In addition, OLBI data completed by MHP in 2020 and 2021 were extracted from 2 published studies, and trend analysis was conducted for the proportion of MHP meeting burnout threshold across 3 time points. We found that the proportion of MHP meeting burnout threshold in 2020, 2021 and 2022 were 76.9%, 87.6% and 77.9% respectively. Professional groups, age, years of experience and income groups were associated with stress and/or burnout. High clinical workload was ranked as the top factor that contributed to stress and burnout while flexible working arrangement was ranked as the top area for improvement so as to reduce stress and burnout. As such, policy makers and hospital management may want to focus on setting clear mental health targets and facilitate manageable clinical workload, build manpower resiliency, optimize resources and provide flexible work arrangements to alleviate stress and burnout among MHP. [ABSTRACT FROM AUTHOR]

Published
2024
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43. Association between Conversion to Shockable Rhythms and Survival with Favorable Neurological Outcomes for Out-of-Hospital Cardiac Arrests.

Author

Ho, Andrew Fu Wah, Lee, Kai Yi, Nur, Shahidah, Fook, Stephanie Chong, Pek, Pin Pin, Tanaka, Hideharu, Sang, Do Shin, Chow, Patrick In-Ko, Tan, Benjamin Yong-Qiang, Lim, Shir Lynn, Ma, Matthew Huei-Ming, Ryoo, Hyun Wook, Lin, Chih-Hao, Kuo, Chan-Wei, Kajino, Kentaro, and Ong, Marcus Eng Hock

Subjects
CARDIOPULMONARY resuscitation, REPORTING of diseases, CONFIDENCE intervals, MULTIVARIATE analysis, RETROSPECTIVE studies, FISHER exact test, MANN Whitney U Test, TREATMENT effectiveness, T-test (Statistics), CARDIAC arrest, EMERGENCY medical services, SURVIVAL analysis (Biometry), DESCRIPTIVE statistics, CHI-squared test, RESEARCH funding, ELECTRIC countershock, ODDS ratio, LOGISTIC regression analysis, EMERGENCY medicine, LONGITUDINAL method
Abstract

The initial cardiac rhythm in out-of-hospital cardiac arrest (OHCA) portends different prognoses and affects treatment decisions. Initial shockable rhythms are associated with good survival and neurological outcomes but there is conflicting evidence for those who initially present with non-shockable rhythms. The aim of this study is to evaluate if OHCA with conversion from non-shockable (i.e., asystole and pulseless electrical activity) rhythms to shockable rhythms compared to OHCA remaining in non-shockable rhythms is associated with better survival and neurological outcomes. OHCA cases from the Pan-Asian Resuscitation Outcomes Study registry in 13 countries between January 2009 and February 2018 were retrospectively analyzed. Cases with missing initial rhythms, age <18 years, presumed non-medical cause of arrest, and not conveyed by emergency medical services were excluded. Multivariable logistic regression analysis was performed to evaluate the relationship between initial and subsequent shockable rhythm, survival to discharge, and survival with favorable neurological outcomes (cerebral performance category 1 or 2). Of the 116,387 cases included. 11,153 (9.6%) had initial shockable rhythms and 9,765 (8.4%) subsequently converted to shockable rhythms. Japan had the lowest proportion of OHCA patients with initial shockable rhythms (7.3%). For OHCA with initial shockable rhythm, the adjusted odds ratios (aOR) for survival and good neurological outcomes were 8.11 (95% confidence interval [CI] 7.62-8.63) and 15.4 (95%CI 14.1-16.8) respectively. For OHCA that converted from initial non-shockable to shockable rhythms, the aORs for survival and good neurological outcomes were 1.23 (95%CI 1.10-1.37) and 1.61 (95%CI 1.35-1.91) respectively. The aORs for survival and good neurological outcomes were 1.48 (95%CI 1.22-1.79) and 1.92 (95%CI 1.3 − 2.84) respectively for initial asystole, while the aOR for survival in initial pulseless electrical activity patients was 0.83 (95%CI 0.71-0.98). Prehospital adrenaline administration had the highest aOR (2.05, 95%CI 1.93-2.18) for conversion to shockable rhythm. In this ambidirectional cohort study, conversion from non-shockable to shockable rhythm was associated with improved survival and neurologic outcomes compared to rhythms that continued to be non-shockable. Continued advanced resuscitation may be beneficial for OHCA with subsequent conversion to shockable rhythms. [ABSTRACT FROM AUTHOR]

Published
2024
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44. Revolutionizing the Management of Large-Core Ischaemic Strokes: Decoding the Success of Endovascular Therapy in the Recent Stroke Trials.

Author

Lim, Gareth Zigui, Lai, Jonathan Yexian, Seet, Christopher Ying Hao, Tham, Carol Huilian, Venketasubramanian, Narayanaswamy, Tan, Benjamin Yong Qiang, Jing, Mingxue, Yeo, Joshua Yee Peng, Myint, May Zin, Sia, Ching-Hui, Teoh, Hock Luen, Sharma, Vijay Kumar, Chan, Bernard Poon Lap, Yang, Cunli, Makmur, Andrew, Ong, Shao Jin, and Yeo, Leonard Leong Litt

Published
2023
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45. Role of plaque inflammation in symptomatic carotid stenosis

Author

Zheng, Yilong, Lim, Mervyn Jun Rui, Tan, Benjamin Yong-Qiang, Chan, Bernard Poon Lap, Paliwal, Prakash, Jonathan, Ong Jia Yuan, Bharatendu, Chandra, Chan, Amanda Chee Yun, Yeo, Leonard Leong Litt, Vijayan, Joy, Hong, Chiew S., Chee, Young Heng, Wong, Lily Y. H., Chen, Jintao, Chong, Victor Yao Feng, Dong, Yanhong, Tan, Chi Hsien, Sunny, Sibi, Teoh, Hock Luen, Sinha, Arvind Kumar, and Sharma, Vijay Kumar

Subjects
Neurology, Neurology (clinical)
Abstract

ObjectivePrior studies have shown that plaque inflammation on FDG-PET and the symptomatic carotid atheroma inflammation lumen-stenosis (SCAIL) score were associated with recurrent ischemic events, but the findings have thus far not been widely validated. Therefore, we aimed to validate the findings of prior studies.MethodsA single-center prospective cohort study that recruited patients with (1) recent TIA or ischemic stroke within the past 30 days, (2) ipsilateral carotid artery stenosis of ≥50%, and (3) were not considered for early carotid revascularization. The (1) maximum standardized uptake value (SUVmax) of the symptomatic carotid plaque, (2) the SCAIL score, and (3) stenosis severity of the symptomatic carotid artery were measured for all patients. The outcomes were (1) a 90-day ipsilateral ischemic stroke and (2) a 90-day ipsilateral symptomatic TIA or major adverse cardiovascular event (MACE).ResultsAmong the 131 patients included in the study, the commonest cardiovascular risk factor was hypertension (95 patients, 72.5%), followed by diabetes mellitus (77 patients, 58.8%) and being a current smoker (64 patients, 48.9%). The median (IQR) duration between the index cerebral ischemic event and recruitment to the study was 1 (0, 2.5) days. The median (IQR) duration between the index cerebral ischemic event and FDG-PET was 5 (4, 7) days. A total of 14 (10.7%) patients had a 90-day stroke, and 41 (31.3%) patients had a 90-day TIA or MACE. On comparison of the predictive performances of the SCAIL score and SUVmax, SUVmax was found to be superior to the SCAIL score for predicting both 90-day ipsilateral ischemic stroke (AUC: SCAIL = 0.79, SUVmax = 0.92; p < 0.001; 95% CI = 0.072, 0.229) and 90-day TIA or MACE (AUC: SCAIL = 0.76, SUVmax = 0.84; p = 0.009; 95% CI = 0.020, 0.143).ConclusionPlaque inflammation as quantified on FDG-PET may serve as a reliable biomarker for risk stratification among patients with ECAD and recent TIA or ischemic stroke. Future studies should evaluate whether patients with significant plaque inflammation as quantified on FDG-PET benefit from carotid revascularization and/or anti-inflammatory therapy.

Published
2023
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47. Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios Are Associated with Recurrent Ischemic Stroke in Patients with Embolic Stroke of Undetermined Source

Author

Li, Tony Y.W., primary, Sia, Ching-Hui, additional, Chan, Bernard P.L., additional, Ho, Jamie S.Y., additional, Leow, Aloysius S., additional, Chan, Mark Y., additional, Kojodjojo, Pipin, additional, Galupo, Mary Joyce, additional, Teoh, Hock-Luen, additional, Sharma, Vijay K., additional, Seet, Raymond C.S., additional, Yeo, Leonard L.L., additional, and Tan, Benjamin Yong-Qiang, additional

Published
2022
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48. Ambient Air Pollution and Acute Ischemic Stroke—Effect Modification by Atrial Fibrillation

Author

Tan, Benjamin Yong-Qiang, primary, Ho, Jamie Sin Ying, additional, Ho, Andrew Fu-Wah, additional, Pek, Pin Pin, additional, Leow, Aloysius Sheng-Ting, additional, Raju, Yogeswari, additional, Sia, Ching-Hui, additional, Yeo, Leonard Leong-Litt, additional, Sharma, Vijay Kumar, additional, Ong, Marcus Eng-Hock, additional, Aik, Joel, additional, and Zheng, Huili, additional

Published
2022
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49. External validation of the Survival After ROSC in Cardiac Arrest (SARICA) score for predicting survival after return of spontaneous circulation using multinational pan-asian cohorts

Author

Rajendram, Maehanyi Frances, primary, Zarisfi, Faraz, additional, Xie, Feng, additional, Shahidah, Nur, additional, Pek, Pin Pin, additional, Yeo, Jun Wei, additional, Tan, Benjamin Yong-Qiang, additional, Ma, Matthew, additional, Do Shin, Sang, additional, Tanaka, Hideharu, additional, Ong, Marcus Eng Hock, additional, Liu, Nan, additional, and Ho, Andrew Fu Wah, additional

Published
2022
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