Search

Your search keyword '"Tan, Kay Sin"' showing total 132 results
Start Over Author "Tan, Kay Sin"
132 results on '"Tan, Kay Sin"'

3. Stroke in Asia

Author

Tan, Kay Sin, primary, Pandian, Jeyaraj Durai, additional, Liu, Liping, additional, Toyoda, Kazunori, additional, Leung, Thomas Wai Hon, additional, Uchiyama, Shinichiro, additional, Kuroda, Sathoshi, additional, Suwanwela, Nijasri C., additional, Aaron, Sanjith, additional, Chang, Hui Meng, additional, and Venketasubramanian, Narayanaswamy, additional

Published
2024
Full Text
View/download PDF

4. RNF213 p.R4810K variant in moyamoya disease in adults and children from a Malaysian tertiary center

Author

Ho, Jun Hui, primary, Tan, Kay Sin, additional, Lim, Wei Kang, additional, Fong, Choong Yi, additional, Toh, Tsun Haw, additional, Lau, Kar Foo, additional, Chan, Zhen Shun, additional, Tai, Sharon Mei Ling, additional, Rahmat, Kartini, additional, Tarmizi Thayaparan, Farah Diana, additional, Murugesu, Sumitha, additional, and Ng, Ching Ching, additional

Published
2023
Full Text
View/download PDF

7. An Evolutionary Artificial Neural Network for Medical Pattern Classification

Author

Tan, Shing Chiang, Lim, Chee Peng, Tan, Kay Sin, Navarro, Jose C., Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Leung, Chi Sing, editor, Lee, Minho, editor, and Chan, Jonathan H., editor

Published
2009
Full Text
View/download PDF

8. Use of Circle-Segments as a Data Visualization Technique for Feature Selection in Pattern Classification

Author

Wang, Shir Li, Loy, Chen Change, Lim, Chee Peng, Lai, Weng Kin, Tan, Kay Sin, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Ishikawa, Masumi, editor, Doya, Kenji, editor, Miyamoto, Hiroyuki, editor, and Yamakawa, Takeshi, editor

Published
2008
Full Text
View/download PDF

11. Global Differences in Risk Factors, Etiology, and Outcome of Ischemic Stroke in Young Adults—A Worldwide Meta-analysis

Author

Jacob, Mina A., primary, Ekker, Merel S., additional, Allach, Youssra, additional, Cai, Mengfei, additional, Aarnio, Karoliina, additional, Arauz, Antonio, additional, Arnold, Marcel, additional, Bae, Hee-Joon, additional, Bandeo, Lucrecia, additional, Barboza, Miguel A., additional, Bolognese, Manuel, additional, Bonardo, Pablo, additional, Brouns, Raf, additional, Chuluun, Batnairamdal, additional, Chuluunbatar, Enkhzaya, additional, Cordonnier, Charlotte, additional, Dagvajantsan, Byambasuren, additional, Debette, Stephanie, additional, Don, Adi, additional, Enzinger, Chris, additional, Ekizoglu, Esme, additional, Fandler-Höfler, Simon, additional, Fazekas, Franz, additional, Fromm, Annette, additional, Gattringer, Thomas, additional, Hora, Thiago F., additional, Jern, Christina, additional, Jood, Katarina, additional, Kim, Young Seo, additional, Kittner, Steven, additional, Kleinig, Timothy, additional, Klijn, Catharina J.M., additional, Kõrv, Janika, additional, Kumar, Vinod, additional, Lee, Keon-Joo, additional, Lee, Tsong-Hai, additional, Maaijwee, Noortje A.M., additional, Martinez-Majander, Nicolas, additional, Marto, João Pedro, additional, Mehndiratta, Man M., additional, Mifsud, Victoria, additional, Montanaro, Vinícius, additional, Pacio, Gisele, additional, Patel, Vinod B., additional, Phillips, Matthew C., additional, Piechowski-Jozwiak, Bartlomiej, additional, Pikula, Aleksandra, additional, Ruiz-Sandoval, Jose, additional, von Sarnowski, Bettina, additional, Swartz, Richard H., additional, Tan, Kay-Sin, additional, Tanne, David, additional, Tatlisumak, Turgut, additional, Thijs, Vincent, additional, Viana-Baptista, Miguel, additional, Vibo, Riina, additional, Wu, Teddy Y., additional, Yesilot, Nilüfer, additional, Waje-Andreassen, Ulrike, additional, Pezzini, Alessandro, additional, Putaala, Jukka, additional, Tuladhar, Anil M., additional, and de Leeuw, Frank-Erik, additional

Published
2022
Full Text
View/download PDF

17. Streptococcus pneumoniae Meningitis and Intracranial Vasculopathy: Clinical Correlation with Improving Transcranial Doppler Hemodynamics

Author

Idris, Mohamad Imran, Tai, Sharon Mei Ling, Tan, Chong Tin, and Tan, Kay Sin

Subjects
cardiovascular system, Neurosonology in Critical Care
Abstract

Streptococcus pneumoniae are Gram-positive bacteria that are responsible for many types of illnesses including pneumonia, sinus infections, and community-acquired meningitis. One important complication of bacterial meningitis is intracranial vasculopathy. Possible etiologies include vasculitis, vasospasm, endocarditis, or intra-arterial thrombosis. We present a case report of S. pneumoniae meningitis treated with antibiotics in which clinical improvement correlated with serial transcranial Doppler ultrasonography (TCD) improvement, suggesting vasospasm or vasculitis as a possible mechanism for intracranial vasculopathy.

Published
2020

18. Stroke Care During the COVID-19 Pandemic: Asian Stroke Advisory Panel Consensus Statement

Author

Pandian, Jeyaraj D., primary, Kusuma, Yohanna, additional, Kiemas, Lyna Soertidewi, additional, Lee, Tsong-Hai, additional, Navarro, Jose C., additional, Nilanont, Yongchai, additional, Suwanwela, Nijasri C., additional, Chiu, Hou-Chang, additional, Kwon, Sun-Uck, additional, Tan, Kay Sin, additional, Thang, Nguyen Huy, additional, Yoon, Byung-Woo, additional, Tan, Ju Lie, additional, and Venketasubramanian, Narayanaswamy, additional

Published
2021
Full Text
View/download PDF

27. A Rare but Disabling Stroke

Author

Lau, Kar Foo, Tan, Kay Sin, Goh, Khean Jin, NORLISAH Ramli, and Tai, Sharon M. L.

Subjects
Central Nervous System Vascular Malformations, Medulla Oblongata, Brain Stem Infarctions, Bulbar Palsy, Progressive, Humans, Female, General Medicine, Middle Aged, Quadriplegia, Magnetic Resonance Imaging, Magnetic Resonance Angiography, Vertebral Artery, Cerebral Angiography
Published
2019

35. Organizational Update

Author

Venketasubramanian, Narayanaswamy, primary, Anderson, Craig, additional, Mehndiratta, Manmohan, additional, Lin, Ruey-Tay, additional, Tan, Kay-Sin, additional, and Huang, Chen-Ya, additional

Published
2017
Full Text
View/download PDF

39. Predictors of functional outcome in patients with stroke thrombolysis in a tertiary hospital in Malaysia.

Author

Mei-Ling Sharon Tai, Khean Jin Goh, Kadir, Khairul Azmi Abdul, Zakaria, Mohd Idzwan, Jun Fai Yap, Kay Sin Tan, Tai, Mei-Ling Sharon, Goh, Khean Jin, Yap, Jun Fai, and Tan, Kay Sin

Subjects
THROMBOLYTIC therapy, STROKE patients, STROKE, UNIVARIATE analysis, LOGISTIC regression analysis, DIABETES
Abstract

Introduction: Intravenous (IV) thrombolysis with alteplase (rt-PA) is effective in ischaemic stroke. The primary objective was to evaluate predictors of functional outcome in acute ischaemic stroke (AIS) patients treated with IV rt-PA. The secondary objective was to assess the outcome with the modified Rankin scale (mRS). We also examined the predictive value of the Totaled Health Risks in Vascular Events (THRIVE) score.Methods: AIS patients treated with IV rt-PA from February 2012 to August 2016 were recruited. Demographic data, National Institutes of Health Stroke Scale (NIHSS) scores, timing and neuroradiological findings were recorded. Patients received a dose of 0.9 mg/kg IV rt-PA within 4.5 hours of symptom onset. mRS score was evaluated at discharge and three months, and good and poor clinical outcomes were defined as scores of 0-2 and 3-6, respectively. Baseline THRIVE scores were assessed.Results: 36 patients received IV rt-PA. 20 (55.6%) patients had an mRS score of 0-2 at three months. Based on THRIVE score, 86.1% had a good or moderately good prognosis. On univariate analysis, poor outcome was associated with NIHSS score before rt-PA (p = 0.03), THRIVE score (p = 0.02), stroke subtype (p = 0.049) and diabetes mellitus (DM; p = 0.06). Multiple logistic regression showed that outcome was significantly associated with NIHSS score before rt-PA (p = 0.032) and DM (p = 0.010).Conclusion: Our newly developed Malaysian IV rt-PA service is safe, with similar outcomes to the published literature. Functional outcome after thrombolysis was associated with baseline NIHSS score and DM. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

43. Circulating MicroRNAs as Biomarkers of Acute Stroke

Author

Sepramaniam, Sugunavathi, primary, Tan, Jun-Rong, additional, Tan, Kay-Sin, additional, DeSilva, Deidre, additional, Tavintharan, Subramaniam, additional, Woon, Fung-Peng, additional, Wang, Chee-Woon, additional, Yong, Fung-Lin, additional, Karolina, Dwi-Setyowati, additional, Kaur, Prameet, additional, Liu, Fu-Jia, additional, Lim, Kai-Ying, additional, Armugam, Arunmozhiarasi, additional, and Jeyaseelan, Kandiah, additional

Published
2014
Full Text
View/download PDF

47. Relapsed and late-onset Nipah encephalitis

Author

Tan, Chong Tin, primary, Goh, Khean Jin, additional, Wong, Kum Thong, additional, Sarji, Sazilah Ahmad, additional, Chua, Kaw Bing, additional, Chew, Nee Kong, additional, Murugasu, Paramsothy, additional, Loh, Yet Lin, additional, Chong, Heng Thay, additional, Tan, Kay Sin, additional, Thayaparan, Tarmizi, additional, Kumar, Shalini, additional, and Jusoh, Mohd Rani, additional

Published
2002
Full Text
View/download PDF

49. TT Genotype of the Methylenetetrahydrofolate Reductase C677T Polymorphism is an Important Determinant for Homocysteine Levels in Multi-Ethnic Malaysian Ischaemic Stroke Patients

Author

Mohamed, Elsa Haniffah Mejia, Tan, Kay Sin, JOHARI MOHD ALI, and Mohamed, Zahurin

Subjects
China, Polymorphism, Genetic, Genotype, Hyperhomocysteinemia, Malaysia, India, General Medicine, Middle Aged, Stroke, Vitamin B 12, Folic Acid, Gene Frequency, Ethnicity, Humans, Point Mutation, Female, Homocysteine, Methylenetetrahydrofolate Reductase (NADPH2)
Abstract

Introduction: The functional point mutation C677T in the methylenetetrahydrofolate reductase (MTHFR) gene, has been reported to contribute to hyperhomocysteinaemia which is a risk factor for atherothrombotic ischaemic strokes. This study evaluated the prevalence of the C677T polymorphism of the gene in Malaysian ischaemic stroke subjects of Malay, Chinese and Indian ethnicities, and its association with homocysteine levels (tHcy). Materials and Methods: A total of 292 subjects were recruited, comprising 150 ischaemic stroke patients and 142 control subjects who were age and sex matched. Plasma homocysteine, serum folate and vitamin B12 were measured in all subjects. Genotyping was carried out using PCR-RFLP. Results: The homocysteine levels were significantly higher (P = 0.001) in the stroke group (11.35 ± 2.75 μmol/L) compared to the control group (10.38 ± 2.79 μmol/L). The MTHFR C677T genotype distribution for the stroke group was 46%, 40% and 14%, respectively for CC, CT and TT genotypes and 59.9%, 33.8% and 6.3%, respectively for the control group. The genotype and allelic frequencies were significantly different between the 2 groups, with P = 0.02 and P = 0.004 respectively. No significant difference was seen in the genotype distribution inter-ethnically. An increasing tHcy was seen with every additional T allele, and the differences in the tHcy for the different genotypes were significant in both the control (P

50. One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke

Author

Amarenco, Pierre, Lavallée, Philippa C, Labreuche, Julien, Albers, Gregory W, Bornstein, Natan M, Canhão, Patrícia, Caplan, Louis R, Donnan, Geoffrey A, Ferro, José M, Hennerici, Michael G, Molina, Carlos, Rothwell, Peter M, Sissani, Leila, Skoloudík, David, Steg, Philippe Gabriel, Touboul, Pierre-Jean, Uchiyama, Shinichiro, Vicaut, Éric, Wong, Lawrence K S, Ameriso, Sebastian, Gandolfo, Claudia Nora, Povedano, Guillermo, Saggesse, Javier, Gandolfo, Claudia, Pavon, Heman, Cancino, Jorge, Toledo, Walter, Huang, Yinin, Gong, Xiping, Ma, Yetao, Mi, Donghu, Song, Tian, Wang, Yilong, Wang, Yongjun, Chandgfend, Fran, Congtao, Guo, Hongyun, Jiao, Intao, He, Jixing, Wu, Linlin, Liu, Liquing, Song, Liwen, Tai, Ran, Liu, Shujuan, Tian, Wenhong, Liu, Tsoi, Tak Hong, Wong, Lawrence, Liu, Roxanna, Flasar, Roman, Zítková, Bed?i?ka, Reif, Michal, Goldemund, David, Neumann, Ji?í, Svá?ková, Dagmar, a?ák, Daniel, Král, Michal, koloudík, David, Václavík, Daniel, Kuliha, Martin, Cabrejo, Lucie, Guidoux, Céline, Hobeanu, Cristina Maria, Lavallée, Philippa, Meseguer, Elena, Audebert, Henrich, Menger, Daniel, Heide, Wolfgang, Lipp, Saskia, Ozalp, Huriye, Sctzmann, Christine, Weimar, Christian, Platzbecker, Katharina, Ringleb, Peter, Hennerici, Michel G, Griebe, Martin, Willmann, Katrin Knoll Olaf, Faiss, Juergen harmut, Dillan, Susan, Kobersteein, Anja, Krimmer, Katharina, Tietz, Sandra, Wienecke, Peter, Hamann, Gerhard, Burkhardt, Nico, Liebetrau, Martin, Mueller, Nadine, Wagner, Michaela, Strivastava, Kelly, Peter, Merwick, Aline, Tanne, David, Cavazzuti, Milena, Anticoli, Sabrina, Toni, Danilo, Nagata, Ken, Okada, Yasushi, Yamagami, Hiroshi, Minematsu, Kazuo, Nakagawara, Jojo, Lee, Byung Chui, Yoon, Byung Woo, Hoe, Ji Hoe, Park, Jong Moo, Abboud, Halim, Koussa, Salam, Awada, Adnan, Tan, Kay Sin, Arauz, Antonio, Gongora, Fernando, Valenzuela, Adrian Infante, Escamilla, Juan M, Canhao, Patrica, Ferro, Jose, Fonseca, Ana Catarina, Correia, Manuel, Tuna, Assuncao, Sternic, Nada, Mijajlovic, Aleksandra Pavlovic Milija, Dupejova, Beata, Szedelyová, Jana, Smirkova, Renata, Segura, Tomas, Rodgriguez, Ana, Silva, Yolanda, Tejada, Javier, Purroy, Francisco, Masjuan, Jaime, Vivancos, Jose, Palomeras, Ernest, Gamemro, Miguel Angel, Arenillas, J F, Calleja, Anna, Rojo, Esther, Buchan, Alastair, Rothwell, Peter, Lee, Tsong Hai, Chang, Ku chou, Huang, Yu-Ching, Lin, Ruey-Tay, Tiamkao, Somsak, and the TIAregistry.org Investigators

Subjects
Male, ABCD(2) SCORE, Medizin, Infarction, 030204 cardiovascular system & hematology, law.invention, 0302 clinical medicine, Randomized controlled trial, law, Recurrence, Risk Factors, Stroke, biology, TIAregistry.org Investigators, Ischemic Attack, Transient, Medicine (all), Composite outcomes, Minor stroke, General Medicine, 11 Medical And Health Sciences, Middle Aged, TIME, Cardiovascular Diseases, Ischemic Attack, Transient, Female, INFARCTION, Life Sciences & Biomedicine, Healthcare system, Risk, Acute coronary syndrome, medicine.medical_specialty, Aged, Humans, 03 medical and health sciences, Medicine, General & Internal, General & Internal Medicine, ABCD2, medicine, cardiovascular diseases, Science & Technology, business.industry, TIA, medicine.disease, RANDOMIZED-TRIAL, INDIVIDUALS, Emergency medicine, biology.protein, Physical therapy, business, 030217 neurology & neurosurgery
Abstract

BACKGROUND Previous studies conducted between 1997 and 2003 estimated that the risk of stroke or an acute coronary syndrome was 12 to 20% during the first 3 months after a transient ischemic attack (TIA) or minor stroke. The TIAregistry.org project was designed to describe the contemporary profile, etiologic factors, and outcomes in patients with a TIA or minor ischemic stroke who receive care in health systems that now offer urgent evaluation by stroke specialists. METHODS We recruited patients who had had a TIA or minor stroke within the previous 7 days. Sites were selected if they had systems dedicated to urgent evaluation of patients with TIA. We estimated the 1-year risk of stroke and of the composite outcome of stroke, an acute coronary syndrome, or death from cardiovascular causes. We also examined the association of the ABCD2 score for the risk of stroke (range, 0 [lowest risk] to 7 [highest risk]), findings on brain imaging, and cause of TIA or minor stroke with the risk of recurrent stroke over a period of 1 year. RESULTS From 2009 through 2011, we enrolled 4789 patients at 61 sites in 21 countries. A total of 78.4% of the patients were evaluated by stroke specialists within 24 hours after symptom onset. A total of 33.4% of the patients had an acute brain infarction, 23.2% had at least one extracranial or intracranial stenosis of 50% or more, and 10.4% had atrial fibrillation. The Kaplan–Meier estimate of the 1-year event rate of the composite cardiovascular outcome was 6.2% (95% confidence interval, 5.5 to 7.0). Kaplan–Meier estimates of the stroke rate at days 2, 7, 30, 90, and 365 were 1.5%, 2.1%, 2.8%, 3.7%, and 5.1%, respectively. In multivariable analyses, multiple infarctions on brain imaging, large-artery atherosclerosis, and an ABCD2 score of 6 or 7 were each associated with more than a doubling of the risk of stroke. CONCLUSIONS We observed a lower risk of cardiovascular events after TIA than previously reported. The ABCD2 score, findings on brain imaging, and status with respect to large-artery atherosclerosis helped stratify the risk of recurrent stroke within 1 year after a TIA or minor stroke. (Funded by Sanofi and Bristol-Myers Squibb.) Supported by an unrestricted grant from Sanofi and Bristol-Myers Squibb.

Catalog

Books, media, physical & digital resources
See catalog results