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32 results on '"Tan, Xinyuan"'

8. Relevant Research of Inflammatory Cytokines Spectrum in Peripheral Blood of Sudden Hearing Loss.

Author

Tan, Xinyuan, Pan, Jing, Cai, Jieqing, Jiang, Shanshan, Shu, Fan, Xu, Muqing, Peng, Hua, Tang, Jie, and Zhang, Hongzheng

Abstract

Objective: To investigate whether there is a correlation between the inflammatory state and the pathogenesis and clinical features of sudden hearing loss (SHL) by studying the expression of inflammation‐related cytokines in the peripheral blood of patients with SHL. Methods: In this work, we analyzed the cytokine profiles of 48 analytes in 38 patients with SHL compared to 38 healthy donors using a multiplex immunoassay. This study used appropriate statistical methods to screen for inflammatory cytokines associated with the pathogenesis of SHL, to analyze their network correlation, and to analyze the relationship between clinical features of SHL and inflammatory cytokines. Results: Several cytokines, including CTACK, Eotaxin, HGF, INF‐α2, IFN‐β, IL‐1β, IL‐1ra, IL‐2Rα, IL‐4, IL‐7, IL‐8, IL‐9, IL‐10, IL‐12(p40), IL‐13, MIG, β‐NGF, SCF, and TNF‐α, exhibited significantly higher levels in the peripheral blood of the SHL group compared to the control group. An inflammatory network composed of multiple cytokines, including IL‐1β, is a risk factor for the development of SHL. Conclusion: This study identified several inflammatory cytokines with elevated expression, which may be linked with the onset of SHL. The results of this study also provide a basis for the theoretical hypothesis of inflammation in SHL. Level of Evidence: 3 Laryngoscope, 134:3293–3301, 2024 [ABSTRACT FROM AUTHOR]

Published
2024
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14. Rheology on high temperature resistant novel trimeric cationic viscoelastic surfactant with KCl.

Author

Tan, Xinyuan, Chen, Jing, Fang, Bo, Liu, Boxiang, Gao, Hang, Li, Kejing, Yu, Luyao, Xu, Ke, Lu, Yongjun, and Qiu, Xiaohui

Subjects
*RHEOLOGY, *HIGH temperatures, *FRACTURING fluids, *CATIONIC surfactants, *SCANNING electron microscopes, *HYDRAULIC fluids, *CATIONIC polymers
Abstract

A novel trimeric cationic surfactant (TEC) has been investigated to use as a hydraulic fracturing fluid thickener with thermal stability. TEC was synthesized with trimethylolpropane triglycidyl ether, erucamidopropyl dimethylamine and hydrochloric acid at 50.0 °C for 7.0 h. The product was compounded with potassium chloride (KCl) for an optimized formulation to form viscoelastic micelles with high-temperature resistance. The apparent viscosity of 5.0 wt%TEC/1.2 wt%KCl fluid remains 23.1 mPa·s after shearing for 90.0 min at 160.0 °C and 100.0 s−1. Three-dimensional (3 D) networks formed by entangled worm-like micelles (WLMs) were observed by an environmental scanning electron microscope. The TEC/KCl solution has a simple formulation and excellent rheological properties, which enriches the viscoelastic surfactant (VES) fracturing fluid class with high-temperature resistance. [ABSTRACT FROM AUTHOR]

Published
2023
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19. Rheology on high temperature resistant novel trimeric cationic viscoelastic surfactant with KCl

Author

Tan, Xinyuan, Chen, Jing, Fang, Bo, Liu, Boxiang, Gao, Hang, Li, Kejing, Yu, Luyao, Xu, Ke, Lu, Yongjun, and Qiu, Xiaohui

Subjects
Polymers and Plastics, education, Physical and Theoretical Chemistry, Surfaces, Coatings and Films
Abstract

A novel trimeric cationic surfactant (TEC) has been investigated to use as a hydraulic fracturing fluid thickener with thermal stability. TEC was synthesized with trimethylolpropane triglycidyl ether, erucamidopropyl dimethylamine and hydrochloric acid at 50.0 °C for 7.0 h. The product was compounded with potassium chloride (KCl) for an optimized formulation to form viscoelastic micelles with high-temperature resistance. The apparent viscosity of 5.0 wt%TEC/1.2 wt%KCl fluid remains 23.1 mPa·s after shearing for 90.0 min at 160.0 °C and 100.0 s−1. Three-dimensional (3 D) networks formed by entangled worm-like micelles (WLMs) were observed by an environmental scanning electron microscope. The TEC/KCl solution has a simple formulation and excellent rheological properties, which enriches the viscoelastic surfactant (VES) fracturing fluid class with high-temperature resistance.

Published
2022
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