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Radix Glycyrrhizae, the dried roots of the Glycyrrhiza glabra plant, is a popular Chinese herbal medicine known for its various health benefits. It is particularly effective in relieving respiratory problems like coughs, sore throats, bronchitis, and asthma. However, there is limited research on the electrical properties of Radix Glycyrrhizae, likely due to its complex composition of phytochemical and antioxidant activities. This research aims to investigate the potential of these active biological compounds and understand their electrochemical properties. In this study, High-Performance Liquid Chromatography (HPLC) analysis revealed that Radix Glycyrrhizae decoction contains significant amounts of flavonoids and saponins, compounds known for their health benefits and therapeutic effects. Further analysis using Fourier Transform Infrared Spectroscopy (FTIR) identified several functional groups, including phenols, alcohols, alkynes, alkenes, ethers, and glycosides, which contribute to the plant's medicinal potential and affect the impedance and dielectric properties of the extract. The antioxidant activity of Radix Glycyrrhizae decoction was also evaluated using DPPH assays, showing similar radical scavenging activity to gallic acid. Dielectric and impedance measurement of Radix Glycyrrhizae extract were performed using an Agilent vector network analyzer and a Hioki impedance analyzer. The dielectric constant measured was consistent across both analyzers. However, the loss factor showed different trends: the vector network analyzer indicated a decrease in the loss factor with increasing frequency in the range of 5 MHz–20 GHz, while the impedance analyzer showed the opposite trend in the frequency range of 4 Hz–5 MHz.

ObjectiveTo construct a single-cell transcriptomic map of testicular tissue under hypobaric hypoxia exposure and perform diversity analysis of supportive cells, aiming to provide new insights into the mechanisms of reproductive toxicity for future research.MethodsTwenty healthy male mice were randomly divided into a control group (n=10) and a hypobaric hypoxia group (n=10). The control group was raised under normal conditions, while the hypobaric hypoxia group was exposed to a low-pressure hypoxic environment(pressure=14 kPa, oxygen content=14.5%). After 6 weeks, testicular tissue from both groups of mice was collected, and the transcriptomic map was obtained using the Singleron MatrixTM single-cell platform and Illumina NovaSeq second-generation sequencing technology. Clustering, pseudo-temporal trajectory analysis, functional analysis, transcription factor and cellular communication research were conducted.ResultsA single-cell transcriptomic map of testicular tissue was successfully constructed, including 6 samples with a total of approximately 49 027 cells covering 11 cell types. Supportive cells were clustered into 4 subgroups using non-negative matrix factorization algorithm. Subgroup 3 may be more sensitive to hypoxic stimulation and could reduce reproductive cell function damage caused by hypobaric hypoxia by affecting PTN expression levels and regulating the cell cycle of spermatogonia. The PTN-PTPR pathway may be an important regulatory node for supportive cells to regulate spermatogonia. Subgroup 4 could regulate the cell cycle of spermatogonia after exposure to hypobaric hypoxia through the KITLG-KIT signaling pathway, thus affecting sperm development.ConclusionsBased on single-cell sequencing technology, the molecular basis and regulatory signals of supportive cells under hypobaric hypoxia exposure is revealed for the first time. It provides an in-depth exploration of the mechanisms of reproductive toxicity induced by hypobaric hypoxia at the single-cell level, offering a new perspective for future clinical research in this field.

Corn is abundant in carbohydrate, protein, carbohydrates and other nutrients. However, because of its large embryo, it is easy to be infected by microorganisms and insects, which leads to the deterioration of corn quality. Therefore, the quality preservation and storage of corn is a challenge. So it is necessary to clarify the rule and change of corn storage quality. Corns with initial water content of 13.04%, 14.03% and 14.99% were taken as reasearch objects in this paper. During storage between 70% relative humidity and 20 ℃ (quasi-low temperature environment) , the changes laws of quality indexes such as bulk density, fatty acid value, germination rate, mold activity and microstructure of corn grain were studied emphatically. Otherwise changes of storage quality of corn at 70% relative humidity and 25 ℃ (room temperature environment) were compared. Therefore it can provide reference for safe storage of high-quality corn. The results demonstrated that the germination rate, fatty acid value and bulk density of corn under 20 ℃ were slower than those under 25 ℃. And they were in the suitable storage range in accordance with the national standard. The number of fungal spores increased sharply with the prolonged storage time. Meanwhile it showed significant correlation with the initial moisture content of corn. In other words, the number of fungal spores for corn under 14.99%w.b was stored for 120 d, and the safe storage periods of corn under 13.04%w.b, 14.03%w.b and 14.99%w.b were 180 d, 180 d and 100 d, respectively. The microstructure of corn kernel changed gradually during storage. It means the appearance changed from smooth and tidy to concave and convex folds. Furthermore, the arrangement of starch granules changed from tight structure to sparse and disordered structure. The main factors of corn quality and microstructure change were corn initial water content and storage time, during storage at quasi-low temperature environment. So the change laws of corn storage quality with different water content were explored, so as to provide new research perspective for maize post-harvest to reduce loss and guarantee qualtiy.

Due to the problems of traditional material transfer equipment such as single working mode and inflexible adjustment of transfer path, intelligent material transfer system has gradually become a research hotspot in the field of logistics transmission. A path planning algorithm based on A* and dynamic window method was proposed for the modular material transmission platform, in order to improve its obstacle avoidance ability during the transfer process by flexibly adjusting the material transfer path. In the global path planning, the smoothness and static obstacle avoidance of the transmission path were realized by improving the A* weight function and integrating the Bezier curve and matrix interference theory. And by introducing the dynamic window method and extracting the global path key points as transition points for local path guidance of the transmission target, dynamic obstacle avoidance was realized when the path falling into local optimization was avoided. The research results showed that the path planning algorithm based on A* and dynamic window method could reduce the total global path length by 4.6% and the total path turning angle by 42.3%, while the dynamic obstacles could be effectively avoided in the local planning, which verified the rationality of the path planning algorithm.

Association standardization of oil and gas pipeline network in China has been in progress for quite a period. However, it is urgent to further accelerate its standardized and high-quality development facing the new requirements, such as high-quality development of the industry, autonomy enhancement, extensive international oil and gas cooperation, etc. In attempt to assist achieving the goal, this research analyzed the data pertaining to association standards for oil and gas pipeline network published in China, focusing on its quantitative change, subject content, field distribution, and drafting units, and employed a complex network algorithm to illustrate the present state of association standardization efforts with a diagram. Based on the aforementioned work, this research found out that there are three main operational modes for association standards organizations, that is professional organizations in this field being totally committed, organizations in relevant field being largely involved and others participating occasionally. The analysis results demonstrate that many problems exist in current association standardization work of oil and gas pipeline network, such as lacking of energy and systematic planning, insufficient in the number of standards, especially of high-quality standards, and the implementation of supervision by industry authorities. The research, in dealing with these problems, promoted several countermeasures, including(1) to establish a correct recognition of the importance of association standardization;(2) to build a national organization to promote coordinated development;(3) leveraging the role of Pipe China to promote openness and integration;(4) to develop a multi-level working mechanism to improve the overall quality; and(5) to refine the responsibilities of the supervising authorities to facilitate high-quality development, etc.

The mineral composition, crystallinity, and dielectric properties of salts can provide valuable insights into the quality and suitability of different types of salt for various applications. In this study, comprehensive analysis of the X-Ray Diffraction (XRD), X-ray fluorescence (XRF) and dielectric analysis of the Ba'kelalan salt, Himalaya salt and Bamboo salt have been investigated. The mineral composition of these salts, encompassing vital elements such as iodine and other trace minerals, significantly influences the salt's nutritional profile and overall excellence. Nonetheless, gauging the dispersion and density of these minerals poses difficulties due to conventional techniques that can be arduous, damaging, and expensive. Sample preparation is carried out before conducting X-ray diffraction (XRD), X-ray fluorescence (XRF), and dielectric analysis. XRD measurements are performed using the Bruker D2 Phaser to identify crystalline material phases. XRD operates on the principle of constructive X-ray interference within crystalline samples. For elemental analysis across a broad spectrum of materials, XRF is employed. Elemental peaks are scanned, starting from the lowest to the highest angle of incidence. The X-ray intensity at characteristic peaks is compared to the standard series. Dielectric spectroscopy analysis examines the dielectric behaviour of Ba'kelalan salt, Himalaya salt, and Bamboo salt. The setup involves a vector network analyser (VNA) paired with an open-ended coaxial probe, utilizing the microwave method. This approach ensures rapid, efficient, and non-destructive measurements of dielectric constants (ε′) and loss factors (ε”). The dielectric permittivity spectra are acquired within the frequency range of 4 GHz–20 GHz. ε′ of these salts increase with frequency. Meanwhile, ε” seem varies insignificantly over frequency. Mineral contents and crystallinity are the crucial factors lead to these responses. Based on the study, the quality and suitability of the selected salts for specific applications can be determined by considering their mineral composition, crystallinity, and dielectric properties in the context of the intended use. This gives an insight for some applications that may benefit from certain minerals or crystalline structures, others may require specific dielectric properties for effective use. Therefore, understanding these properties allows for decision-making in choosing the right type of salt for a given purpose, whether it's for foods, medical, industrial, healthcare, and technological applications.

The special operation mode of high-speed railway will generate a large amount of harmonics. The harmonics will be transmitted to the 220kV side high-voltage cables through the traction transformer, and harmonic voltages will be generated on the cable sheath, threatening the safe operation of the cables. In this paper, on the basis of the measured harmonic data of the traction substation, a harmonic source model based on the measured data is established, which solves the complex problem of harmonic source modeling and can accurately reflect the actual operating conditions of high-speed trains. On this basis, the harmonic voltage characteristics of the cable sheath on the 220kV side of the high-speed railway under the three working conditions of traction, regenerative braking and inertia are simulated and calculated, and the effects of cable length, cable grounding method, and harmonic current parameters on the harmonic voltage are explored. Affect the law. The results show that under different operation modes of high-speed rail, the harmonic voltage of the sheath far exceeds the normal operation of the power frequency, and the maximum value of the harmonic voltage of the cable sheath can reach 454V under the traction condition; Under working conditions, the overvoltage of the metal sheath is greatly affected by the grounding method of the cable, the length of the cable and the harmonic current content. The above research results have important reference significance for the safe operation of electrified railways.

The cable partial discharge vibration signal is often polluted by noise. It is necessary to denoise the signal, improve the signal-to-noise ratio, and then realize the feature extraction of the vibration signal. Therefore, this paper builds a cable partial discharge test platform, collects the time-domain waveform of vibration signals under different working conditions, analyzes the noise reduction effect of ensemble empirical mode decomposition clearing repetition interval threshold noise reduction method under different threshold functions, and analyzes the difference and approximation degree between the simulated signal and the real signal after noise reduction by using signal-to-noise ratio and correlation, By comparing the difference of statistical characteristics in different defects before and after noise reduction, the wavelet threshold denoising method is established synchronously and compared with the proposed method. The results show that the high-frequency part of the vibration signal has obvious random noise components, and the effective frequency is mainly concentrated in the low-frequency band; The smoothing shear absolute deviation penalty threshold function has the smoothest curve after noise reduction and the highest approximation to the real signal. The high-frequency noise component is eliminated, and the low-frequency band frequency component is effectively retained. The method proposed in this paper can be extended to the noise reduction of vibration signals of other industrial equipment and provide technical support for the signal noise reduction of various industrial equipment.

Objective: To investigate the types of volatile flavor components and their content differences in different vinegar ages of Hexi balsamic vinegar. Methods: Headspace solid-phase microextraction-gas chromatography mass spectrometry (HS-SPME-GC-MS) was used to analyze the volatile aroma components of five groups of Hexi balsamic vinegar of different years in 2017, 2018, 2019, 2020 and 2021. Results: A total of 117 volatile aroma components were detected in 5 groups of Hexi balsamic vinegar of different vinegar ages, 25 alcohol substances, 13 aldehydes, 14 acids, 24 esters and 41 other (ethers, phenols, alkane heterocyclic compounds, etc.) substances, the proportion of the quantity of substances in each of the five categories of substances to the total quantity of substances is 21.4%, 11.1%, 12.0%, 20.5% and 35.0%, respectively. The volatile aroma substances of Hexi balsamic vinegar in 2017, 2018, 2019, 2020 and 2021 were 29, 31, 35, 41 and 41 substances, respectively. With the prolongation of aging time, the number of alcohols showed a "W" pattern; the number of aldehydes, acids and other substances showed a rising trend before decreasing; the overall trend of the number of esters was not obvious. The relative contents of aldehydes and other substances showed an overall increasing trend; the relative contents of acids and esters showed an overall decreasing trend; the relative contents of alcohols showed an increasing and then decreasing trend. Conclusion: There were differences in the types and contents of volatile aroma components of Hexi balsamic vinegar with different vinegar ages, and the quality of Hexi balsamic vinegar in 2019 was relatively better among the five groups of samples studied.

In 2017, with the rising Chinese film market, some Chinese private film and television companies began to establish other businesses, many of which failed. The aim of this study was to investigate the future development route of a Chinese private film and television company. In this paper, a detailed study of the case was employed to utilize facts and information such as the number of Chinese theater lines, the representative Chinese film box office, and Bona Films’ yearly financial statement. As a result of the article’s investigation, first and foremost, the Bona Film is in a loss situation in 4Ps due to the outbreak. Thus, Bona Film needs government policy support. Then, from the standpoint of the 4Ps, Bona Film is primarily concerned with the investment, production, and distribution of Nationalist films. The product category is too narrow. Finally, Bona Film’s cinema is too small to build a complete Bona Film system.

YouTube, Instagram, games, animations and infographics are some visual media outlets that Malaysian learners opt for in the 21st-century classroom. Nonetheless, pupils in primary school nowadays are not able to retain English vocabulary due to teachers' chalk-and-talk method in teaching vocabulary. Hence, this research aims to innovate the use of ‘Gamifographics’ with primary school pupils in learning vocabulary as it is one of the most appealing means to better understand and retain vocabulary. To support the research, four theories are applied which are Cognitivism learning theory, Bloom’s Taxonomy, Gamified-Learning Theory and Self-determination theory. A Design and Development Research (DDR) approach, ADDIE Model was employed in the study to innovate the use of ‘Gamifographics’ with primary school Year 4 pupils in an urban and a suburban school in learning vocabulary. Generally, findings revealed that "Gamifographics" has gained positive perceptions in learning vocabulary as they are visually attractive, easy to understand and remember as well as keep the readers' interest in continuing reading. In addition, "Gamifographics" promotes learning motivation, improves learning engagement and ultimately leads to a positive learning outcome. Thus, it is suggested that utilising of "Gamifographics" in learning vocabulary among primary English learners should be regarded.

Effects of silkworm pupae powder concentration, glucose concentration, cultural time and initial pH of culture medium on the fermentation of carotenoid were investigated. The results of single-factor experiments showed that when silkworm pupae powder concentration was 7.5 g/L, with glucose concentration at 30 g/L and cultural time of 4 d, as well as initial pH of culture medium of7.0, the carotenoid yield reached the maximum value of 14.51 mg/L, which was 46.9% higher than that of the control. In order to make further improvement on the carotenoid production, the orthogonal tests were performed and the results showed that the order of the factors affecting the carotenoid yield was as follows: cultural time>silkworm pupae powder concentration>glucose concentration>pH. The carotenoid yield reached the maximum value of 14.88 mg/L under the optimum fermentation conditions. Silkworm pupae powder concentration was 7.5 g/L, with glucose concentration at 30 g/L, and cultural time of 4 d, plus pH value at 6.0.

ObjectiveTo determine whether kidney transplants performed during weekends have worse outcomes than those performed during weekdays.MethodsFor this systematic review, PubMed, EMBASE, and the Cochrane Library (January 2000 to January 2023) were searched. We examined the survival rates of patients and grafts for hospital inpatients admitted during weekends and those admitted during weekdays. To be included, the study had to be in English and had to provide discrete survival data around weekends versus weekdays, including patients who were admitted as inpatients over the weekend.ResultsFive studies (n = 163,506 patients) were examined. The hazards ratio (HR) of the survival rate of patients with weekend transplantation was 1.01 (95% confidence interval [CI], 0.96 to 1.06) when compared with patients with weekday transplantation. Patients who had renal transplant on weekends had an overall allograft survival HR of 1.01 (95% CI, 0.99 to 1.03) and death-censored allograft survival HR of 1.01 (95% CI, 0.98 to 1.04). Comparison of length of hospital stay, rejection, surgical complications, and vascular complications between renal transplants on weekends and those on weekdays showed no statistical difference.ConclusionHospital inpatients admitted for renal transplantation during weekends have a survival rate similar to that of inpatients admitted during weekdays. The weekend effect of renal transplantation was very weak; hence, transplantations done during weekends and weekdays are both appropriate.

ObjectiveTo study the transcriptomic changes of astrocytes in the brain of rats exposed to methamphetamine （METH） and its possible mechanism in neurotoxicity.MethodsThe rats were intraperitoneally injected with METH （15 mg/kg） every 12 h for 8 times in total to establish the subacute rat model of METH. After the model was successfully established, the striatum was extracted, and astrocytes were separated by the magnetic bead method. Transcriptome sequencing was performed on selected astrocytes, and the differentially expressed genes were analyzed by gene ontology （GO） and Kyoto Encyclopedia of Genes and Genomes （KEGG） pathway enrichment analysis.ResultsA total of 876 differentially expressed genes were obtained by transcriptome sequencing, including 321 up-regulated genes and 555 down-regulated genes. GO analysis revealed that differentially expressed genes were mainly concentrated in cell structure, biological process regulation, extracellular matrix and organelle functions. KEGG pathway enrichment analysis showed that steroids biosynthesis, fatty acid biosynthesis, peroxisome proliferators-activated receptor （PPAR）, adenosine 5’-monophosphate-activated protein kinase （AMPK） and other signaling pathways were significantly changed.ConclusionMETH can cause structural changes of astrocytes through multiple targets, among which cellular structure, steroids biosynthesis and fatty acid biosynthesis may play an important role in nerve injury, providing a new idea for forensic identification of METH related death.

The spatial variability is an inherent uncertainty of soils. The random field theory is used to represent the spatial variability of soils, and the random field discretization is performed by the Karhunen-Loève (KL) expansion method. Using the slope upper bound analysis based on the discrete mechanism, the discretization results of the internal friction angle random field at each point in the space are considered when generating the velocity discontinuity surface. And the strength reduction technique, bisection searching, and sequential quadratic programming method are combined to solve the safety factor of slopes. The first-order reliability method (FORM) and subset simulation (SS) are employed for slope reliability analysis. Given the characteristics of SS and the shear strength reduction technique, an optimization algorithm coupling the two is proposed to improve computational efficiency. By calculating and analyzing an earth slope, the similarities and differences between FORM and SS based on the KL expansion method in solving the slope reliability index and failure consequence are clarified. The influence of the coefficient of variation of soil strength parameters on the slope reliability index and failure consequence is investigated, providing a theoretical basis for risk analysis and prevention of slopes.

Nanoporous materials have attracted great attention in the fields of adsorption and membrane separation due to their remarkable nanoscale spatial effects. As an extension of inorganic porous materials, metal organic framework (MOF) has been widely used in gas-phase storage and separation, liquid-phase adsorption separation and catalytic reaction due to its large specific surface area, high porosity and adjustable pore structure. In this paper, the types of MOF are classified, and the synthesis methods and particle size control mechanism of MOF materials were compared. Among them, the advantages of solvothermal synthesis were emphatically introduced. At the same time, the problems and limitations of MOF materials in adsorption separation research were summarized systematically, and the advanced preparation technology of composite membrane based on MOF materials was prospected; the application of MOF in gas storage separation, liquid adsorption separation and membrane separation was summarized. Finally, for the preparation of composite membrane, the idea of improving the compatibility of MOF material and organic membrane by changing the synthesis method of MOF was proposed.

Natural resources are the most critical material basis for national economic and social development, and the key guarantee for improving national viability. With the development of national economy and the progress of society, people’s awareness of the importance of resources is also growing, and the issue of resources has begun to become an important topic of common concern for governments around the world. At a time when non-renewable resources such as coal and natural gas are in urgent need, and energy shortage has gradually become a problem endangering global economic development, more and more countries have begun to actively implement the “sunshine plan”, that is, to develop and utilize sunlight resources to find new impetus for economic and social development. Solar energy resource is a very important resource, which is inexhaustible, non-polluting, and relatively cheap and can be used at will. Vigorously developing and using solar energy is the most effective way to solve the shortage of resources and achieve sustainable economic development. Therefore, the application in the highway field is very necessary to promote the construction of distributed photovoltaic power generation system.

Electron paramagnetic resonance (EPR) with the use of exogenous spin probes is an indispensable tool to measure pH in vitro and in vivo. Monophosphonated tetrathiatriarylmethyl (p1TAM) radicals are so far the most promising EPR probes for pH measurement. However, their biological applications were limited by extremely low efficiency in synthesis and potential albumin binding, such that they could not be administered systematically. In the present work, an efficient procedure for p1TAM synthesis was reported, with a total yield of 25% from the corresponding triarylmethanol (compared to 1.6% with the commonly used procedure). Further PEGylation prevented the interaction between p1TAM and albumin. The EPR spectra of nondeuterated (POP) and deuterated (dPOP) PEGylated derivatives of p1TAM were also recorded at different pH values. The two probes had similar pH sensitivities with pKa values of 6.80 and 6.79, respectively. POP had a much more complex EPR spectrum than dPOP, with the latter always exhibiting simple EPR doublet signals regardless of the pH. These results suggested that dPOP is more advantageous for pH measurement, relative to POP and p1TAM. Moreover, dPOP was shown to have excellent biological stability and high O2 sensitivity, and thus might have the potential to be used as the probe for simultaneous pH and O2 measurements in biological system.

To achieve the optimum use and efficient thermal management of two-layer electroosmosis pumping systems in microdevices, this paper studies the transient hydrodynamical features in two-layer electroosmotic flow of power-law nanofluids in a slit microchannel and the corresponding heat transfer characteristics in the presence of viscous dissipation. The governing equations are established based on the Cauchy momentum equation, continuity equation, energy equation, and power-law nanofluid model, which are analytically solved in the limiting case of two-layer Newtonian fluid flow by means of Laplace transform and numerically solved for two-layer power-law nanofluid fluid flow. The transient mechanism of adopting conducting power-law nanofluid as a pumping force and that of pumping nonconducting power-law nanofluid are both discussed by presenting the two-layer velocity, flow rates, temperature, and Nusselt number at different power-law rheology, nanoparticle volume fraction, electrokinetic width and Brinkman number. The results demonstrate that shear thinning conducting nanofluid represents a promising tool to drive nonconducting samples, especially samples with shear thickening features. The increase in nanoparticle volume fraction promotes heat transfer performance, and the shear thickening feature of conducting nanofluid tends to suppress the effects of viscous dissipation and electrokinetic width on heat transfer.

The article is devoted to substantiation of theoretical aspects of the problem of preparation of future teachers of art disciplines for innovative activity in China. The preparation of future teachers of art disciplines for innovation is considered by the authors as a system, as it can be described as an ordered set of interconnected components, which is a holistic formation. Among such components of the system are the purpose, content, methods, forms, means and so on. Readiness for innovative professional activity is considered by the authors as an integrative quality of personality, which is formed due to the emergence of a psychological system of activity, and its structure is identical to the structure of the corresponding functional psychological system. The components of such a system are the motives and goals of the activity, its information base and program, the decision-making unit and the subsystem of personality qualities, which is professionally important. It is proved that readiness and ability for innovative activity is provided by efficiency of introduction of the newest achievements of science, creative mastering of the advanced pedagogical experience of education, search of the most rational means of optimization of educational process and extracurricular activity of future teachers of art disciplines (group work, problem scientific groups, societies, etc).

An improved model called TR-YOLO is employed for Asian food object detection. Firstly, the ViT module is introduced into the model to make better use of global features. Secondly, the Swin Transformer module is introduced on the three detection branches to output the features. Finally, the Mconcat feature fusion method is proposed, which enables the model to learn the feature weights to assign feature channels independently. The experimental results show that the TR-YOLO model further improves the detection accuracy.

Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common sleep disorder characterized by repeated pharyngeal collapse with partial or complete obstruction of the upper airway. This study investigates the biomechanics of upper airway collapse of OSASH patients during natural sleep. Computerized tomography (CT) scans and data obtained from a device installed on OSASH patients, which is comprised of micro pressure sensors and temperature sensors, are used to develop a pseudo three-dimensional (3D) finite element (FE) model of the upper airway. With consideration of the gravity effect on the soft palate while patients are in a supine position, a fluid–solid coupling analysis is performed using the FE model for the two respiratory modes, eupnea and apnea. The results of this study show that the FE simulations can provide a satisfactory representation of a patient’s actual respiratory physiological processes during natural sleep. The one-way valve effect of the soft palate is one of the important mechanical factors causing upper airway collapse. The monitoring data and FE simulation results obtained in this study provide a comprehensive understanding of the occurrence of OSAHS and a theoretical basis for the individualized treatment of patients. The study demonstrates that biomechanical simulation is a powerful supplementation to clinical monitoring and evaluation.