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23 results on '"Tang, Jiake"'

5. Reduced plasma cholesterol in Plasmodium falciparum infection: A meta-analysis

Author

You, Yao, primary, Fan, Hua, additional, Zhang, Shenghui, additional, Hu, Siqi, additional, Tang, Jiake, additional, Chen, Chen, additional, Wen, Wen, additional, Wang, Chunyi, additional, Cheng, Yongran, additional, Zhou, Mengyun, additional, Feng, Zhanhui, additional, Tan, Tao, additional, Qi, Guanming, additional, Zhao, Wenbin, additional, Zhang, Xingwei, additional, Wang, Mingwei, additional, and Dai, Lili, additional

Published
2023
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6. Olfactory dysfunction after COVID‐19: metanalysis reveals persistence in one-third of patients 6 months after initial infection

Author

Hu, Siqi, primary, Zhang, Shenghui, additional, You, Yao, additional, Tang, Jiake, additional, Chen, Chen, additional, Wang, Chunyi, additional, Wen, Wen, additional, Wang, Mingwei, additional, Chen, Juan, additional, Luo, Lin, additional, Cheng, Yongran, additional, Zhou, Mengyun, additional, Zhao, Xuezhi, additional, Tan, Tao, additional, Qi, Guanming, additional, and Feng, Zhanhui, additional

Published
2023
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7. Multidrug-resistant infection in COVID-19 patients: A meta-analysis

Author

Hu, Siqi, primary, You, Yao, additional, Zhang, Shenghui, additional, Tang, Jiake, additional, Chen, Chen, additional, Wen, Wen, additional, Wang, Chunyi, additional, Cheng, Yongran, additional, Zhou, Mengyun, additional, Feng, Zhanhui, additional, Tan, Tao, additional, Qi, Guanming, additional, Wang, Mingwei, additional, and Liu, Xiaoyan, additional

Published
2023
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11. A meta-analysis of the association between calprotectin and the severity of COVID-19

Author

Mao, Qin, Wang, Chunyi, Wen, Wen, Zhou, Mengyun, Tang, Jiake, Chen, Chen, Cheng, Yongran, Wu, Qi, Zhang, Xingwei, Feng, Zhanhui, and Wang, Mingwei

Subjects
Adult, Microbiology (medical), Infectious Diseases, SARS-CoV-2, COVID-19, Humans, Letter to the Editor, Leukocyte L1 Antigen Complex, Severity of Illness Index, Biomarkers
Published
2022

12. Association of Metabolic Dysfunction-Associated Fatty Liver Disease With Left Ventricular Diastolic Function and Cardiac Morphology

Author

Peng, Dandan, primary, Yu, Zhenqiu, additional, Wang, Mingwei, additional, Shi, Junping, additional, Sun, Lei, additional, Zhang, Yuanyuan, additional, Zhao, Wenbin, additional, Chen, Chen, additional, Tang, Jiake, additional, Wang, Chunyi, additional, Ni, Jie, additional, Wen, Wen, additional, and Jiang, Jingjie, additional

Published
2022
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18. Air Quality During The COVID-19 Epidemic in China

Author

Lv, Shijin, primary, Wen, Wen, additional, Wang, Chunyi, additional, Chen, Chen, additional, Tang, Jiake, additional, Cheng, Yongran, additional, Zhou, Mengyun, additional, Wu, Qi, additional, Zhang, Xingwei, additional, Wang, Ming-wei, additional, Feng, Zhanhui, additional, and Yang, Dong, additional

Published
2022
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22. Investigating the impact of empagliflozin on the retina of diabetic mice

Author

Chen, Juan, Zhang, Shenghui, You, Yao, Hu, Siqi, Tang, Jiake, Chen, Chen, Wen, Wen, Tang, Ting, Yu, Qingwen, Tong, Xuhan, Wang, Chunyi, Zhao, Wenbin, Fu, Xinyan, Zhang, Xingwei, Wang, Mingwei, and Gong, Wenyan

Abstract

Background Diabetic retinopathy (DR) frequently results in compromised visual function, with hyperglycemia-induced disruption of the blood-retinal barrier (BRB) through various pathways as a critical mechanism. Existing DR treatments fail to address early and potentially reversible microvascular alterations. This study examined the effects of empagliflozin (EMPA), a selective Sodium-glucose transporter 2 (SGLT2) inhibitor, on the retina of db/db mice. The objective of this study is to investigate the potential role of EMPA in the prevention and delay of DR.Methods db/dbmice were randomly assigned to either the EMPA treatment group (db/db?+?Emp) or the model group (db/db), while C57 mice served as the normal control group (C57). Mice in the db/db?+?Emp group received EMPA for eight weeks. Body weight, fasting blood glucose (FBG), and blood VEGF were subsequently measured in all mice, along with the detection of specific inflammatory factors and BRB proteins in the retina. Retinal SGLT2 protein expression was compared using immunohistochemical analysis, and BRB structural changes were observed via electron microscopy.Results EMPA reduced FBG, blood VEGF, and retinal inflammatory factors TNF-a, IL-6, and VEGF levels in the eye tissues of db/dbmice. EMPA also increased Claudin-1, Occludin-1, and ZO-1 levels while decreasing ICAM-1 and Fibronectin, thereby preserving BRB function in db/dbmice. Immunohistochemistry revealed that EMPA reduced SGLT2 expression in the retina of diabetic mice, and electron microscopy demonstrated that EMPA diminished tight junction damage between retinal vascular endothelial cells and prevented retinal vascular basement membrane thickening in diabetic mice.Conclusion EMPA mitigates inflammation and preserves BRB structure and function, suggesting that it may prevent DR or serve as an effective early treatment for DR.

Published
2024
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23. Metabolic-associated fatty liver disease and the risk of cardiovascular disease

Author

Zhang, Pengwei, Dong, Xianhui, Zhang, Wei, Wang, Shiyin, Chen, Chen, Tang, Jiake, You, Yao, Hu, Siqi, Zhang, Shenghui, Wang, Chunyi, Wen, Wen, Zhou, Mengyun, Tan, Tao, Qi, Guanming, Li, Li, and Wang, Mingwei

Abstract

1We conducted a retrospective study using the 1988–1994 National Health and Nutrition Examination Surveys (NHANES III) database, including 11673 individuals.2In conclusion, the 10-year CVD risk in MAFLD patients was higher when compared with NAFLD patients, and this risk increased with liver fibrosis severity within a certain range.

Published
2022
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