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In many aspects of life quality, bio-contaminants and indoor air quality have had catastrophic consequences, including a negative impact on human health with an increased prevalence of allergic respiratory reactions, asthma, and infectious diseases. We aimed to evaluate the quality of indoor air environment and find out the association between human health and indoor air pollution and also to assess the physical health status of a group of Saudi and non-Saudi populations during this pandemic. Also, we aimed to assess the most common health condition or symptoms associated with ventilation. A questionnaire was distributed online to test indoor air quality, ventilation status, common signs and symptoms of any allergy or mental status and their relationship to certain variables. A total of 362 respondents were included. Before living in the current home, flu or Influenza and chapped lips were more prevalent than allergies and chapped lips signs while living in the current home. (12.2% , 10.8% vs. 18.5% , 13.55% before and after respectively) Multiple colds were the second most common symptom (10.2%). Hoarse voice and headaches were the least common symptoms experienced; each constituted 4.4%. During the COVID-19 Pandemic, most respondents wore a facemask, approximately 76.5%; and almost one-third of respondents had bright natural light inside the current home (43.1%). The presence of natural light within the current home was significantly associated with symptoms experienced during living in the current house (p

Due to high level of blood sugar, some glucose molecules are attached to the normal hemoglobin which is known as glycated hemoglobin (HbA1c). HbA1c indicates the average blood glucose levels over the past 6 to 8 weeks. Therefore, it has been recommended as a screening tool for the detection and monitoring of diabetes mellitus. HbA1c at high levels are associated with various metabolic disorder and other disease. In the present review, we summarized risk factors associated with increased level of HbA1c and its clinical significance.