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35 results on '"Tarta, Cristi"'

1. The Robotic Approach in Rectal Cancer

Author

Duta, Ciprian, primary, Pantea, Stelu, additional, Brebu, Dan, additional, Dobrescu, Amadeus, additional, Lazar, Caius, additional, Botoca, Kitty, additional, Tarta, Cristi, additional, and Lazar, Fulger, additional

Published
2023
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2. The Predictive Role of Serum Lipid Levels, p53 and ki-67, According to Molecular Subtypes in Breast Cancer: A Randomized Clinical Study

Author

Faur, Ionut Flaviu, primary, Dobrescu, Amadeus, additional, Clim, Ioana Adelina, additional, Pasca, Paul, additional, Prodan-Barbulescu, Catalin, additional, Tarta, Cristi, additional, Neamtu, Andreea-Adriana, additional, Brebu, Dan, additional, Neamtu, Carmen, additional, Rosu, Mihai, additional, Duta, Ciprian, additional, Clim, Andreea, additional, Lazar, Gabriel, additional, and Totolici, Bogdan, additional

Published
2024
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3. VRAM Flap for Pelvic Floor Reconstruction after Pelvic Exenteration and Abdominoperineal Excision

Author

Faur, Ionut Flaviu, primary, Clim, Adelina, additional, Dobrescu, Amadeus, additional, Prodan, Catalin, additional, Hajjar, Rami, additional, Pasca, Paul, additional, Capitanio, Marco, additional, Tarta, Cristi, additional, Isaic, Alexandru, additional, Noditi, George, additional, Nati, Ionel, additional, Totolici, Bogdan, additional, Duta, Ciprian, additional, and Lazar, Gabriel, additional

Published
2023
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4. The Cavernous Nerve Injury Rat Model: A Pictorial Essay on Post-Radical Prostatectomy Erectile Dysfunction Research

Author

Latcu, Silviu Constantin, primary, Novacescu, Dorin, additional, Buciu, Victor-Bogdan, additional, Dumitru, Cristina-Stefania, additional, Ceausu, Raluca Amalia, additional, Raica, Marius, additional, Cut, Talida Georgiana, additional, Ilina, Razvan, additional, Malita, Daniel Claudiu, additional, Tarta, Cristi, additional, and Cumpanas, Alin Adrian, additional

Published
2023
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6. Lipid Profile Paradox: Investigating Improved Lipid Levels in Diabetic Mellitus Patients with Foot Ulcer Infections—A Prospective Descriptive Study

Author

Ardelean, Andrei, primary, Neamtu, Andreea-Adriana, additional, Balta, Diana-Federica, additional, Neamtu, Carmen, additional, Goldis, Dan, additional, Rosu, Mihai, additional, Nesiu, Alexandru, additional, Moldovan, Silviu, additional, Tarta, Cristi, additional, and Totolici, Bogdan Dan, additional

Published
2023
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7. The Value of Tumor Infiltrating Lymphocytes (TIL) for Predicting the Response to Neoadjuvant Chemotherapy (NAC) in Breast Cancer according to the Molecular Subtypes

Author

Faur, Ionut Flaviu, primary, Dobrescu, Amadeus, additional, Clim, Adelina Ioana, additional, Pasca, Paul, additional, Prodan-Barbulescu, Catalin, additional, Gherle, Bogdan Daniel, additional, Tarta, Cristi, additional, Isaic, Alexandru, additional, Brebu, Dan, additional, Duta, Ciprian, additional, Totolici, Bogdan, additional, and Lazar, Gabriel, additional

Published
2023
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9. The Value of Tumor Infiltrating Lymphocytes (TIL) for Prediction of Response to Neoadjuvant Chemotherapy (NAC) in Breast Cancer According to the Molecular Subtype

Author

Faur, Ionut Flaviu, primary, Dobrescu, Amadeus, additional, Clim, Adelina, additional, Pasca, Paul, additional, Prodan-Barbulescu, Catalin, additional, Gherle, Bogdan Daniel, additional, Tarta, Cristi, additional, Isaic, Alexandru, additional, Brebu, Dan, additional, Duta, Ciprian, additional, Totolici, Bogdan, additional, and Lazar, Gabriel, additional

Published
2023
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16. Health-Related Quality of Life and Stress-Related Disorders in Patients with Complicated Diverticular Disease under Conservative Management.

Author

Mateescu, Tudor, Miutescu, Bogdan, Nicola, Alin, Oancea, Cristian, Barata, Paula Irina, Tarta, Cristi, Fulger, Lazar, and Paleru, Cristian

Subjects
TREATMENT of diverticulosis, CONSERVATIVE treatment, KRUSKAL-Wallis Test, CONFIDENCE intervals, ANALYSIS of variance, AGE distribution, CROSS-sectional method, FISHER exact test, DIVERTICULOSIS, TREATMENT effectiveness, COMPARATIVE studies, QUALITY of life, QUESTIONNAIRES, DESCRIPTIVE statistics, CHI-squared test, STATISTICAL sampling, COMPUTED tomography, PSYCHOLOGICAL stress, DISEASE complications
Abstract

Diverticular disease is a common gastrointestinal disorder with increasing prevalence in advanced age. This study aimed to investigate the impact of age and complexity of diverticulitis on health-related quality of life (HRQoL) and stress-related disorders. A cross-sectional study was conducted on 180 patients, including adults (18–64 years) with complicated diverticular disease, the elderly (≥65 years) with complicated diverticular disease, and a control group with uncomplicated symptomatic diverticular disease. HRQoL and stress-related disorders were assessed using the SF-36, GIQLI, HADS, and PHQ-9 questionnaires at baseline and six months after the initial episode of diverticulitis. At diagnosis, the adult group had significantly lower mean physical and mental scores compared with the elderly and control groups (p < 0.001). At the 6-month follow-up, the mean physical score increased for all groups, but the difference between adults and the elderly remained significant (p = 0.028). The adult group had a significantly lower mean GIQLI score at diagnosis compared with the elderly and control groups (p < 0.001), although after 6 months it increased and the difference became insignificant. Anxiety scores at diagnosis were significantly higher in the adult group compared with the control group (p = 0.009). The complexity of diverticulitis and age significantly impacted HRQoL at diagnosis, with adults having lower physical and mental scores compared with elderly patients and controls. Although improvements were observed after 6 months, the difference between adults and the elderly remained significant for physical HRQoL scores. This highlights the need for tailored management strategies and psychosocial support to optimize patient outcomes across age groups and diverticulitis complexity. [ABSTRACT FROM AUTHOR]

Published
2023
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28. Laparoscopic Repair for Perforated Peptic Ulcer: A Retrospective Study

Author

Vărcuş, Flore, primary, Beuran, Mircea, additional, Lica, Ioan, additional, Turculet, Claudiu, additional, Cotarlet, Adrian Valentin, additional, Georgescu, Stefan, additional, Vintila, Dan, additional, Sabău, Dan, additional, Sabau, Alexandru, additional, Ciuce, Constantin, additional, Bintintan, Vasile, additional, Georgescu, Eugen, additional, Popescu, Razvan, additional, Tarta, Cristi, additional, and Surlin, Valeriu, additional

Published
2016
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31. MARKERS OF ANGIOGENESIS IN RECTAL CANCERS.

Author

GOLDIS, DAN, TARTA, CRISTI, LAZAR, FULGER, NEAMTU, CARMEN, and TOTOLICI, BOGDAN

Subjects
*NEOVASCULARIZATION, *RECTAL cancer, *CANCER invasiveness
Abstract

Surgery reach its limits in treating rectal cancers. Old fashion chemotherapy has so many adverse effects and the survival rates became steady for the last decades. Efforts were made in two other directions prevention of rectal cancers by large population screenings, and the other was research of intimate mechanism of rectal cancer progression and identifying new markers for better targeted new anti-cancer drugs. We intend to emphasize the role of angiogenesis markers in actual stage of research in order to settle new goals for our research. We identified three possible paths in evaluation of the rectal cancer angiogenesis suitable for our research: microvessel density quantified by CD34 and CD105, morphometric analysis of the intratumor and peritumor vessel marked with CD34 and CD105 in order to achieve new patterns of progressing for rectal cancer, and a combined analyses of VEGF and podoplanin.The biological behaviour of rectal cancers is tailored by many factors, most of them activating different pathways of vascular growth. Reasearch should focus on the relation between these factors and finding new ways of targeting multiple factors during chemotherapy in order to restrict tumor blood supply by slowing the angiogenesis. [ABSTRACT FROM AUTHOR]

Published
2015

33. The Robotic Approach in Rectal Cancer

Author

Duta, Ciprian, Lazar, Fulger, Tarta, Cristi, Botoca, Kitty, Lazar, Caius, Dobrescu, Amadeus, Brebu, Dan, and Pantea, Stelu

Subjects
Medical
Abstract

Since a robotic surgical system was developed in the early 1990s and the first robotic-assisted radical prostatectomy was reported in 2001, robotic surgery has spread in many surgical specialties, changing surgical management. Currently, compared to other colorectal procedures, robotic surgery appears to offer great benefits for total mesorectal excision for rectal cancer. Abdominal cavity other procedures such as right hemicolectomy and high anterior resection are relatively uncomplicated and can be performed easily by laparoscopic surgery. First reports have focused on the clinical benefits of robotic rectal cancer surgery compared with laparoscopic surgery. The indications for robotic and laparoscopic rectal cancer surgery are not different. The recently published results of the ROLARR trial, comparing robot-assisted TME to laparoscopic TME, show no advantages of robot assistance in terms of intraoperative complications, postoperative complications, plane of surgery, 30-day mortality, bladder dysfunction, and sexual dysfunction. A drawback of the study is the variability in experience of the participating surgeons in robotic surgery. After correction of this confounder, an advantage for robotic assistance was suggested in terms of risk of conversion to open surgery. For robotic rectal cancer surgery to become the preferred minimally invasive option, it must demonstrate that it does not have the technical difficulties and steep learning curve of laparoscopic surgery. Robotic surgery has several technical advantages over open and laparoscopic surgery. The system provides a stable operating platform, three-dimensional imaging, articulating instruments and a stable surgeon controlled camera which is mainly beneficial in areas where space and maneuverability is limited such as the pelvis.

Published
2019

34. Laparoscopic repair of perforated peptic ulcer.

Author

Varcus F, Paun I, Duta C, Dobrescu A, Frandes M, and Tarta C

Subjects
Anastomotic Leak epidemiology, Conversion to Open Surgery statistics & numerical data, Emergencies, Humans, Laparoscopy methods, Length of Stay statistics & numerical data, Peptic Ulcer Perforation complications, Postoperative Complications epidemiology, Postoperative Complications etiology, Reoperation statistics & numerical data, Risk Factors, Shock, Septic etiology, Treatment Outcome, Peptic Ulcer Perforation surgery
Abstract

Introduction: Perforations of the peptic ulcers (PPUs) are the most common cause of emergency surgery among the complications of the gastroduodenal ulcers and the leading cause for morbidity and mortality due to secondary peritonitis and sepsis. PPU is a condition in which laparoscopic perforation repair (LPR) is an optimal solution. It makes possible the identification of the perforation's site and allows closure of the perforation and the subsequent peritoneal lavage, as in an open repair (OR) but without the large upper mid-abdominal incision. The main objective of this review was to evaluate the latest reported results in the laparoscopic treatment of the PPU., Evidence Acquisition: Using PubMed and EMBASE databases between 1989 and June 2017 we did an extensive electronic literature search. The search terms used were "laparoscopic perforated peptic ulcer." Inclusion criteria were all the published studies that reported the outcomes of LPR and LPR compared with OR for PPU were included in the analysis. The exclusion criteria included animal or laboratory studies, pediatric surgery trials, papers reporting less than 30 cases of LPR, clinical trials without major outcomes, and other language then English., Evidence Synthesis: There were 32 studies included, counting 3488 patients with LPR and 5208 with OR. OR patients had more frequent shock at admission and had a higher ASA risk class. LPR patients had shorter hospital stays with two days, morbidity (11.12% vs. 14.71% OR) and mortality (1.95% vs. 8.35% OR) were lower. Leakage was three times higher in LPR arm (2.18% vs. 0.79% OR). Conversion occurred in 4.18% overall. The three primary reasons for conversions were the size of the perforation, the inability to locate the perforation and technical difficulties., Conclusions: LPR showed similar or better results than OR in terms of morbidity, mortality, operation time and hospital stay, caution is needed as the OR patients tend to be more shocked or with higher ASA at presentation. The higher leakage rate after LPR should be addressed in the training of the laparoscopic surgeons or other safety measures should be developed and employed.

Published
2018
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