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Organizational behavior is a field of study that investigates the impact that individuals, groups and structure have in the organizations in order to use this knowledge to promote the improvement of organizational effectiveness (CHIAVENATO, 1999). The Executive Secretary is in this context because when working with people not just leadership but the other employees of the organization its behavior should be analyzed so that it can improve and add value to their daily work, as well as, in the decisions that will have. In this study we used the quantitative research that to Roech (2005), is the kind of research examining the data obtained is used for statistical analysis, seeks to ensure accuracy of the results, avoiding distortions of analysis and interpretations. The techniques of data collection are: interviews, questionnaires, tests and observation. Data collection was done through questionnaires sent to the Executive Secretaries of companies located in Porto Alegre (RS) and the Metropolitan Area, and returned by email. The research was also the type Survey that to Roech (2005) is based on an interrogation of the participants which will be made to several questions that are of interest to the researcher. This method has the advantage, firstly, the application, and second, the data obtained are reliable because the answers are limited to the alternatives mentioned and the use of fixed response reduces the variability in results that can be caused by differences interviewed.Com o avanço da Globalização e o aumento da busca por bons resultados, o ser humano precisa, cada vez mais, de algo que o faça perseguir seus objetivos e os de sua empresa. Em todo este contexto de melhorias contínuas, o empregado busca o melhor para a organização demonstrando dedicação ao seu trabalho, e esta, por sua vez, deve demonstrar o reconhecimento deste colaborador. Em função deste contexto, vê-se a importância de se estudar o comportamento humano no trabalho, onde pode-se identificar quais são os pontos importantes neste processo no contraponto da organização versus colaborador. A Secretária Executiva tem entra neste contexto, pois ao trabalhar com várias pessoas, não somente chefia, seu comportamento deve ser analisado para que esta possa melhorar e agregar valor ao seu trabalho diário, bem como nas decisões que deverá tomar. Este estudo visa mostrar, através de um estudo realizado com Secretárias Executivas, em uma pesquisa onde utilizou-se o método quantitativo descritivo com análise no método Survey sendo as respostas obtidas através do questionário onde foi possível obter um maior conhecimento do comportamento humano no trabalho da Secretária Executiva.

Organizational behavior is a field of study that investigates the impact that individuals, groups and structure have in the organizations in order to use this knowledge to promote the improvement of organizational effectiveness (CHIAVENATO, 1999). The Executive Secretary is in this context because when working with people not just leadership but the other employees of the organization its behavior should be analyzed so that it can improve and add value to their daily work, as well as, in the decisions that will have. In this study we used the quantitative research that to Roech (2005), is the kind of research examining the data obtained is used for statistical analysis, seeks to ensure accuracy of the results, avoiding distortions of analysis and interpretations. The techniques of data collection are: interviews, questionnaires, tests and observation. Data collection was done through questionnaires sent to the Executive Secretaries of companies located in Porto Alegre (RS) and the Metropolitan Area, and returned by email. The research was also the type Survey that to Roech (2005) is based on an interrogation of the participants which will be made to several questions that are of interest to the researcher. This method has the advantage, firstly, the application, and second, the data obtained are reliable because the answers are limited to the alternatives mentioned and the use of fixed response reduces the variability in results that can be caused by differences interviewed.

A rapid and effective isocratic chromatographic procedure is successfully developed to determinate methotrexate (MTX) entrapment efficiency (EE) in polymeric nanocapsules using reversed-phase high-performance liquid chromatography. The method employed a RP-C18 Shimadzu Shim-pack CLC-ODS (150 mm × 4.6 mm, 5 µm) column with mobile phase constituted by a mixture of water–acetonitrile–tetrahydrofuran (65:30:5 v/v/v; pH 3.0) at a flow rate of 0.8 mL/min. The eluate is monitored with a UV detector set at 313 nm. The parameters used in the validation process are: linearity, specificity, precision, accuracy, and limit of quantitation (LOQ). The linearity is evaluated by a calibration curve in the concentration range of 10–50 µg/mL and presented a correlation coefficient of 0.9998. The polymers (PLA or PLA-PEG), oil, and surfactants used in the nanocapsule formulation did not interfere with analysis and the recovery was quantitative. The intra and inter-day assay relative standard deviation were less than 0.72%. Results are satisfactory, and the method proved to be adequate for the determination of methotrexate in nanocpsules formulations. [ABSTRACT FROM AUTHOR]