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Hemorrhage due to a ruptured pancreaticoduodenal artery aneurysm is potentially fatal. We describe a case of a 51-year-old man, incidentally diagnosed with an inferior pancreaticoduodenal artery aneurysm associated with probable congenital hypoplasia of the celiac axis and its branches. Considering the rupture risk, we performed an ilio-hepatic artery bypass with an autologous vein graft and aneurysmorrhaphy. The postoperative course was uneventful. At the 24-month follow-up, the bypass was patent, with no aneurysm recurrence. The ilio-hepatic artery bypass is effective and preserves visceral blood flow. However, the iliac artery is susceptible to occlusive disease, and long-term follow-up is required.

An aberrant arterial aneurysm with pulmonary sequestration is rare. Here, we report about a 35-year-old man who had no symptoms related to pulmonary sequestration. Computed tomography revealed an aberrant arterial aneurysm with an 18 mm in diameter with intralobar pulmonary sequestration, which gradually increased in size to 27 mm over 5 years. The patient underwent thoracic endovascular aortic repair with coil embolization for the aneurysmal distal branches to prevent aneurysm rupture. The postoperative course was unremarkable without a need for lobectomy. During a 1-month follow-up period, the aneurysm shrunk with no endoleaks. Stent-graft placement and coil embolization represent an effective and less invasive treatment option to completely block systemic arterial flow and unexpected retrograde backflow and control the expansion of the aneurysm.

Complex formations in aqueous solutions (pH = 9.7∼11.8) containing uranyl ions (5 or 20 mM, M = mol dm-3) carbonate ions (0.04, 0.12, or 1.05 M), and hydrogen peroxide have been studied using UV-vis and NMR spectroscopic methods. In 17O NMR spectra, a peak due to uranyl “yl” oxygen of UO2(CO3)34− was observed at 1099 ppm, and with an increase in [H2O2], the intensity of this peak decreases and two peaks were newly appeared at 1094 and 1103 ppm, respectively. In 13C NMR spectra, a carbonate peak of UO2(CO3)34− and two peaks due to other carbonate complexes were observed at 170.4, 169.8, and 169.9 ppm, respectively. In addition, it was found that the peak intensities of 17O signals observed at 1094 and 1103 ppm change in proportion to those of 13C signals observed at 169.9 and 169.8 ppm. From the NMR peak areas, two new uranyl complexes were proposed as species with the molar ratio of UO22+: CO2- =1: 2. Furthermore, the UV-vis absorption spectral changes with the addition of H2O2 to the aqueous solutions containing uranyl ions and carbonate ions were analyzed by the least-square fitting on the basis of the formation of UO2(O2)(CO3)24− and (UO2)2(O2)(CO3)46- complexes except for UO2(CO3)34-. As a result, the formation constants (logK) for UO2(O2)(CO3)24− and (UO2)2(O2)(CO3)46− were estimated as 7.9 ± 0.6 and 31.9 ± 0.6, respectively. Using the obtained formation constants, the molar absorptivity of UO2(O2)(CO3)2 and (UO2)2(O2)(CO3)46- were evaluated. It was found that the UO2(O2)(CO3)24- complex has an absorption peak at 350.6 nm and a shoulder around 420.0 nm, and their ɛ values are 1260 ± 21 and 893 ± 18 M-1 cm-1, and that the absorption spectrum of (UO2)2(O2)(CO3)46- have a shoulder around 346.0 nm (ɛ = 1720 ± 24).

This study was designed to determine the effect of lipid microspheres containing prostaglandin E 1 (lipo PGE 1 ) on cis -diamminedichloroplatinum (CDDP) accumulation in primary and lung metastatic lesions. Sixty mice were divided into four groups, depending on whether or not an intra-foot-pad injection of Dunn osteosarcoma cells had been administered and on whether or not an intraperitoneal injection of lipo PGE 1 had been administered. CDDP was injected intraperitoneally into all the mice 6 weeks after the inoculation. Tumor colonies of spontaneous metastases in the left lung were found in 21 out of 30 tumor-inoculated mice at autopsy. Tissue platinum concentrations in the lungs with metastatic colonies and in the foot-pad tumors were significantly higher in the lipo PGE 1 -administered mice than in those without treatment. Terminal deoxytransferase-mediated dUTP nick end labeling (TUNEL) assay showed marked localization of dying cells in the lung metastatic lesions of the lipo PGE 1 -administered mice. The results of this study showed that pretreatment with lipo PGE 1 may augment the anti-tumor effects of CDDP at the tumor site.

We first briefly introduce the various kinds of basic CMOS four-valued logic circuit that can be suitably employed for circuits with clock pulses. Using these, the design of multiple-valued MAX and MIN circuits with many inputs, each of which has two quaternary figures, are developed. It is shown that the number of MOS transistors required for these circuits can be reduced in comparison to binary circuits having equivalent functions. Successful simulation results using SPICE-2 for the circuit operations are given.