1. Association of cardiac changes with serum adiponectin and resistin levels in obese and overweight children
- Author
-
Tayfun Guldur, Gülendam Koçak, Cemşit Karakurt, Ozlem Nalbantoglu, Ayşehan Aknc, Saim Yologlu, Sibel Gurbuz, and Ozlem Elkran
- Subjects
Male ,medicine.medical_specialty ,Adolescent ,Heart Ventricles ,Diastole ,Overweight ,Ventricular Dysfunction, Left ,Decreased adiponectin level ,Insulin resistance ,Internal medicine ,medicine ,Humans ,Resistin ,Obesity ,Child ,Echocardiography, Doppler, Pulsed ,Anthropometry ,Adiponectin ,business.industry ,nutritional and metabolic diseases ,General Medicine ,Stroke volume ,medicine.disease ,Echocardiography, Doppler, Color ,Cholesterol ,Blood pressure ,Case-Control Studies ,Cardiology ,Female ,Hypertrophy, Left Ventricular ,Insulin Resistance ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Biomarkers - Abstract
OBJECTIVES To investigate serum adiponectin and resistin levels in childhood obesity and their relationship with cardiac changes and insulin resistance. METHODS Seventy-one obese and 24 overweight children and 40 healthy children and adolescents were selected for the study. Height and weight measurements, BMI values and BMI SD score values were obtained for each individual. After blood pressure measurement, left ventricular wall thickness, left ventricular mass, stroke volume, cardiac output, systolic and diastolic functions of the left ventricle were measured using an M-mode, two dimensional color-coded echocardiography device. Blood samples of the individuals were obtained for fasting blood sugar, total blood cholesterol, triglyceride, low-density lipoprotein (LDL) cholesterol, very low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, insulin, C-peptide, adiponectin and resistin values. RESULTS Cholesterol and LDL values, homeostasis model assessment of insulin resistance, fasting insulin and fasting C-peptide values of the obese and overweight groups were higher (P
- Published
- 2013
- Full Text
- View/download PDF