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17,345 results on '"Taylor, M. A."'

1. Understanding the Needs of Autistic Post-Secondary Students

Author

Taylor M. Schembri-Mutch, Adam W. McCrimmon, and Michael L. Zwiers

Abstract

Autistic students are a growing subgroup within post-secondary schooling; however, little is known about barriers to their success in that context. Research suggests autistic students face more challenges to completing post-secondary education than neurotypical students, but findings often rely on expert opinion and fail to incorporate first-hand perspectives. To address this gap, a qualitative inquiry into barriers to success for autistic post-secondary students was conducted. Thematic Analysis yielded 10 themes in three categories, while two separate cross-cutting themes emerged; themes interact with one another, intensifying concerns of autistic students. Findings can support post-secondary institutions to reflect on the extent to which these barriers are present for their autistic students and modify support services accordingly.

Published
2024
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2. Discovery of a dormant 33 solar-mass black hole in pre-release Gaia astrometry

Author

Gaia Collaboration, Panuzzo, P., Mazeh, T., Arenou, F., Holl, B., Caffau, E., Jorissen, A., Babusiaux, C., Gavras, P., Sahlmann, J., Bastian, U., Wyrzykowski, Ł., Eyer, L., Leclerc, N., Bauchet, N., Bombrun, A., Mowlavi, N., Seabroke, G. M., Teyssier, D., Balbinot, E., Helmi, A., Brown, A. G. A., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Barbier, A., Biermann, M., Creevey, O. L., Ducourant, C., Evans, D. W., Guerra, R., Hutton, A., Jordi, C., Klioner, S. A., Lammers, U., Lindegren, L., Luri, X., Mignard, F., Nicolas, C., Randich, S., Sartoretti, P., Smiljanic, R., Tanga, P., Walton, N. A., Aerts, C., Bailer-Jones, C. A. L., Cropper, M., Drimmel, R., Jansen, F., Katz, D., Lattanzi, M. G., Soubiran, C., Thévenin, F., van Leeuwen, F., Andrae, R., Audard, M., Bakker, J., Blomme, R., Castañeda, J., De Angeli, F., Fabricius, C., Fouesneau, M., Frémat, Y., Galluccio, L., Guerrier, A., Heiter, U., Masana, E., Messineo, R., Nienartowicz, K., Pailler, F., Riclet, F., Roux, W., Sordo, R., Gracia-Abril, G., Portell, J., Altmann, M., Benson, K., Berthier, J., Burgess, P. W., Busonero, D., Busso, G., Cacciari, C., Cánovas, H., Carrasco, J. M., Carry, B., Cellino, A., Cheek, N., Clementini, G., Damerdji, Y., Davidson, M., de Teodoro, P., Delchambre, L., Dell'Oro, A., Garcia, E. Fraile, Garabato, D., García-Lario, P., Haigron, R., Hambly, N. C., Harrison, D. L., Hatzidimitriou, D., Hernández, J., Hestroffer, D., Hodgkin, S. T., Jamal, S., de Fombelle, G. Jevardat, Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Lorca, A., Marchal, O., Marrese, P. M., Moitinho, A., Muinonen, K., Campos, M. Nuñez, Oreshina-Slezak, I., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Riello, M., Rimoldini, L., Robin, A. C., Roegiers, T., Sarro, L. M., Schultheis, M., Smith, M., Sozzetti, A., Utrilla, E., van Leeuwen, M., Weingrill, K., Abbas, U., Ábrahám, P., Aramburu, A. Abreu, Ahmed, S., Altavilla, G., Álvarez, M. A., Anders, F., Anderson, R. I., Varela, E. Anglada, Antoja, T., Baig, S., Baines, D., Baker, S. G., Balaguer-Núñez, L., Balog, Z., Barache, C., Barros, M., Barstow, M. A., Bartolomé, S., Bashi, D., Bassilana, J. -L., Baudeau, N., Becciani, U., Bedin, L. R., Bellas-Velidis, I., Bellazzini, M., Beordo, W., Bernet, M., Bertolotto, C., Bertone, S., Bianchi, L., Binnenfeld, A., Blanco-Cuaresma, S., Bland-Hawthorn, J., Blazere, A., Boch, T., Bossini, D., Bouquillon, S., Bragaglia, A., Braine, J., Bratsolis, E., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Butkevich, A. G., Buzzi, R., Camut, A., Cancelliere, R., Cantat-Gaudin, T., Guilarte, D. Capilla, Carballo, R., Carlucci, T., Carnerero, M. I., Carretero, J., Carton, S., Casamiquela, L., Casey, A., Castellani, M., Castro-Ginard, A., Ceraj, L., Cesare, V., Charlot, P., Chaudet, C., Chemin, L., Chiavassa, A., Chornay, N., Chosson, D., Cooper, W. J., Cornez, T., Cowell, S., Crosta, M., Crowley, C., Reyes, M. Cruz, Dafonte, C., Ponte, M. Dal, David, M., de Laverny, P., De Luise, F., De March, R., De Ridder, J., de Torres, A., del Peloso, E. F., Delbo, M., Delgado, A., Delisle, J. -B., Demouchy, C., Denis, E., Dharmawardena, T. E., Di Giacomo, F., Diener, C., Distefano, E., Dolding, C., Dsilva, K., Enke, H., Fabre, C., Fabrizio, M., Faigler, S., Fatović, M., Fedorets, G., Fernández-Hernández, J., Fernique, P., Figueras, F., Fouron, C., Fragkoudi, F., Gai, M., Galinier, M., Garcia-Serrano, A., García-Torres, M., Garofalo, A., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomboc, A., Gomez, A., González-Santamaría, I., Gosset, E., Granvik, M., Barrera, V. Gregori, Gutiérrez-Sánchez, R., Haywood, M., Helmer, A., Hidalgo, S. L., Hilger, T., Hobbs, D., Hottier, C., Huckle, H. E., Jiménez-Arranz, Ó., Campillo, J. Juaristi, Kaczmarek, Z., Kervella, P., Khanna, S., Kontizas, M., Kordopatis, G., Korn, A. J., Kóspál, Á, Kostrzewa-Rutkowska, Z., Kruszyńska, K., Kun, M., Lambert, S., Lanza, A. F., Lebreton, Y., Lebzelter, T., Leccia, S., Lecoutre, G., Liao, S., Liberato, L., Licata, E., Livanou, E., Lobel, A., López-Miralles, J., Loup, C., Madarász, M., Mahy, L., Mann, R. G., Manteiga, M., Marinoni, S., Marcellino, C. P., Marshall, D. J., Mascarenhas, D., Marchant, J. M., Lozano, J. Martín, Masip, A., Marconi, M., Pina, D. Marín, Polo, L. Martin, Martín-Fleitas, J. M., Mastrobuono-Battisti, A., McMillan, P. J., Meichsner, J. G. Marton, Merc, J., Messina, S., Millar, N. R., Mints, A., Mohamed, D., Molina, D., Molinaro, R., Monguió, M., Montegriffo, P., Monti, L., Mora, A., Morbidelli, R., Morris, D., Mudimadugula, R., Muraveva, T., Musella, I., Nagy, Z., Nardetto, N., Navarrete, C., Oh, S., Ordenovic, C., Orenstein, O., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Pallas-Quintela, L., Pawlak, M., Penttilä, A., Pesciullesi, P., Pinamonti, M., Plachy, E., Planquart, L., Plum, G., Poggio, E., Pourbaix, D., Price-Whelan, A. M., Pulone, L., Rabin, V., Rainer, M., Raiteri, C. M., Ramos, P., Ramos-Lerate, M., Ratajczak, M., Fiorentin, P. Re, Regibo, S., Reylé, C., Ripepi, V., Riva, A., Rix, H. -W., Rixon, G., Robert, G., Robichon, N., Robin, C., Romero-Gómez, M., Rowell, N., Mieres, D. Ruz, Rybicki, K. A., Sadowski, G., Sellés, A. Sagristà, Sanna, N., Santoveña, R., Sarasso, M., Sarmiento, M. H., Riera, C. Sarrate, Sciacca, E., Ségransan, D., Semczuk, M., Shahaf, S., Siebert, A., Slezak18, E., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spitoni, E., Spoto, F., Squillante, L. A., Steele, I. A., Steidelmüller, H., Surdej, J., Szabados, L., Taris, F., Taylor, M. B., Teixeira, R., Tepper-Garcia, T., Thuillot, W., Tolomei, L., Tonello, N., Torra, F., Elipe, G. Torralba, Trabucchi, M., Trentin, E., Tsantaki, M., Turon, C., Ulla, A., Unger, N., Valtchanov, I., Vanel, O., Vecchiato, A., Vicente, D., Villar, E., Weiler, M., Zhao, H., Zorec, J., Zucker, S., Župić, A., and Zwitter, T.

Subjects
Astrophysics - Astrophysics of Galaxies, Astrophysics - Solar and Stellar Astrophysics
Abstract

Gravitational waves from black-hole merging events have revealed a population of extra-galactic BHs residing in short-period binaries with masses that are higher than expected based on most stellar evolution models - and also higher than known stellar-origin black holes in our Galaxy. It has been proposed that those high-mass BHs are the remnants of massive metal-poor stars. Gaia astrometry is expected to uncover many Galactic wide-binary systems containing dormant BHs, which may not have been detected before. The study of this population will provide new information on the BH-mass distribution in binaries and shed light on their formation mechanisms and progenitors. As part of the validation efforts in preparation for the fourth Gaia data release (DR4), we analysed the preliminary astrometric binary solutions, obtained by the Gaia Non-Single Star pipeline, to verify their significance and to minimise false-detection rates in high-mass-function orbital solutions. The astrometric binary solution of one source, Gaia BH3, implies the presence of a 32.70 \pm 0.82 M\odot BH in a binary system with a period of 11.6 yr. Gaia radial velocities independently validate the astrometric orbit. Broad-band photometric and spectroscopic data show that the visible component is an old, very metal-poor giant of the Galactic halo, at a distance of 590 pc. The BH in the Gaia BH3 system is more massive than any other Galactic stellar-origin BH known thus far. The low metallicity of the star companion supports the scenario that metal-poor massive stars are progenitors of the high-mass BHs detected by gravitational-wave telescopes. The Galactic orbit of the system and its metallicity indicate that it might belong to the Sequoia halo substructure. Alternatively, and more plausibly, it could belong to the ED-2 stream, which likely originated from a globular cluster that had been disrupted by the Milky Way., Comment: 23 pages, accepted fro publication in A&A Letters. New version with small fixes

Published
2024
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3. Banach lattices with upper $p$-estimates: free and injective objects

Author

García-Sánchez, E., Leung, D. H., Taylor, M. A., and Tradacete, P.

Subjects
Mathematics - Functional Analysis, 46B42, 06B25, 47B60
Abstract

We study the free Banach lattice $FBL^{(p,\infty)}[E]$ with upper $p$-estimates generated by a Banach space $E$. Using a classical result of Pisier on factorization through $L^{p,\infty}(\mu)$ together with a finite dimensional reduction, it is shown that the spaces $\ell^{p,\infty}(n)$ witness the universal property of $FBL^{(p,\infty)}[E]$ isomorphically. As a consequence, we obtain a functional representation for $FBL^{(p,\infty)}[E]$. More generally, our proof allows us to identify the norm of any free Banach lattice over $E$ associated with a rearrangement invariant function space. After obtaining the above functional representation, we take the first steps towards analyzing the fine structure of $FBL^{(p,\infty)}[E]$. Notably, we prove that the norm for $FBL^{(p,\infty)}[E]$ cannot be isometrically witnessed by $L^{p,\infty}(\mu)$ and settle the question of characterizing when an embedding between Banach spaces extends to a lattice embedding between the corresponding free Banach lattices with upper $p$-estimates. To prove this latter result, we introduce a novel push-out argument, which when combined with the injectivity of $\ell^p$ allows us to give an alternative proof of the subspace problem for free $p$-convex Banach lattices. On the other hand, we prove that $\ell^{p,\infty}$ is not injective in the class of Banach lattices with upper $p$-estimates, elucidating one of many difficulties arising in the study of $FBL^{(p,\infty)}[E]$., Comment: 37 pages

Published
2024

5. Transitioning From Trainee to Practicing Pathologist: A Prospective Multi- institutional Survey of the Challenges Early Career Anatomic Pathologists Encounter When Entering Independent Practice. (Education in Pathology and Laboratory Medicine)

Author

Katsakhyan, Levon, Devins, Kyle M., Jenkins, Taylor M., and Song, Sharon J.

Subjects
Pathologists -- Practice -- Training -- Beliefs, opinions and attitudes
Abstract

* Context.--Pathology training programs generally prepare graduates well for the workforce, but there may be other aspects to navigating a job that make the transition from being a trainee to a practicing pathologist challenging. Objective.--To identify perceived challenges of independent practice for early career pathologists and assess how these impressions evolve throughout their first year. Design.--A survey was distributed to 12 anatomic pathology fellows from 4 institutions near the end of their final training year, and 6 months and 1 year after starting their first job. The surveys queried participants' comfort level with signing out cases independently and interacting with colleagues/trainees via Likert attitude scale questions, with free-text segments to elaborate on challenges experienced. Results.--The response rate to all 3 surveys was 100%. Confidence and comfort level with different aspects of independent sign-out increased incrementally over time. Main challenges encountered at 6 months included a high case load, signing out cases in areas outside of their subspecialty, time management, balancing teaching while signing out, laboratory issues, and developing relationships with clinicians. At 12 months, main challenges included time management, high case load, understaffing, laboratory issues, and signing out cases in areas outside of their subspecialty. Conclusions.--This study identified real-time challenges faced by those adjusting to their first year of independent practice. By gaining a better understanding of the factors that make this transition challenging, we can find tailored ways to support our early career pathologists. (Arch Pathol Lab Med. 2024;148:1063-1066; doi: 10.5858/arpa.2023-0378-EP), Pathology training programs generally prepare graduates well for the workforce, particularly with respect to medical knowledge and diagnostic skills in anatomic pathology. (1) However, the transition to becoming a practicing [...]

Published
2024
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12. De novo variants in the RNU4-2 snRNA cause a frequent neurodevelopmental syndrome

Author

Chen, Yuyang, Dawes, Ruebena, Kim, Hyung Chul, Ljungdahl, Alicia, Stenton, Sarah L., Walker, Susan, Lord, Jenny, Lemire, Gabrielle, Martin-Geary, Alexandra C., Ganesh, Vijay S., Ma, Jialan, Ellingford, Jamie M., Delage, Erwan, D’Souza, Elston N., Dong, Shan, Adams, David R., Allan, Kirsten, Bakshi, Madhura, Baldwin, Erin E., Berger, Seth I., Bernstein, Jonathan A., Bhatnagar, Ishita, Blair, Ed, Brown, Natasha J., Burrage, Lindsay C., Chapman, Kimberly, Coman, David J., Compton, Alison G., Cunningham, Chloe A., D’Souza, Precilla, Danecek, Petr, Délot, Emmanuèle C., Dias, Kerith-Rae, Elias, Ellen R., Elmslie, Frances, Evans, Care-Anne, Ewans, Lisa, Ezell, Kimberly, Fraser, Jamie L., Gallacher, Lyndon, Genetti, Casie A., Goriely, Anne, Grant, Christina L., Haack, Tobias, Higgs, Jenny E., Hinch, Anjali G., Hurles, Matthew E., Kuechler, Alma, Lachlan, Katherine L., Lalani, Seema R., Lecoquierre, François, Leitão, Elsa, Fevre, Anna Le, Leventer, Richard J., Liebelt, Jan E., Lindsay, Sarah, Lockhart, Paul J., Ma, Alan S., Macnamara, Ellen F., Mansour, Sahar, Maurer, Taylor M., Mendez, Hector R., Metcalfe, Kay, Montgomery, Stephen B., Moosajee, Mariya, Nassogne, Marie-Cécile, Neumann, Serena, O’Donoghue, Michael, O’Leary, Melanie, Palmer, Elizabeth E., Pattani, Nikhil, Phillips, John, Pitsava, Georgia, Pysar, Ryan, Rehm, Heidi L., Reuter, Chloe M., Revencu, Nicole, Riess, Angelika, Rius, Rocio, Rodan, Lance, Roscioli, Tony, Rosenfeld, Jill A., Sachdev, Rani, Shaw-Smith, Charles J., Simons, Cas, Sisodiya, Sanjay M., Snell, Penny, St Clair, Laura, Stark, Zornitza, Stewart, Helen S., Tan, Tiong Yang, Tan, Natalie B., Temple, Suzanna E. L., Thorburn, David R., Tifft, Cynthia J., Uebergang, Eloise, VanNoy, Grace E., Vasudevan, Pradeep, Vilain, Eric, Viskochil, David H., Wedd, Laura, Wheeler, Matthew T., White, Susan M., Wojcik, Monica, Wolfe, Lynne A., Wolfenson, Zoe, Wright, Caroline F., Xiao, Changrui, Zocche, David, Rubenstein, John L., Markenscoff-Papadimitriou, Eirene, Fica, Sebastian M., Baralle, Diana, Depienne, Christel, MacArthur, Daniel G., Howson, Joanna M. M., Sanders, Stephan J., O’Donnell-Luria, Anne, and Whiffin, Nicola

Published
2024
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20. Gaia Focused Product Release: Sources from Service Interface Function image analysis -- Half a million new sources in omega Centauri

Author

Gaia Collaboration, Weingrill, K., Mints, A., Castañeda, J., Kostrzewa-Rutkowska, Z., Davidson, M., De Angeli, F., Hernández, J., Torra, F., Ramos-Lerate, M., Babusiaux, C., Biermann, M., Crowley, C., Evans, D. W., Lindegren, L., Martín-Fleitas, J. M., Palaversa, L., Mieres, D. Ruz, Tisanić, K., Brown, A. G. A., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Arenou, F., Barbier, A., Creevey, O. L., Ducourant, C., Eyer, L., Guerra, R., Hutton, A., Jordi, C., Klioner, S. A., Lammers, U., Luri, X., Mignard, F., Randich, S., Sartoretti, P., Smiljanic, R., Tanga, P., Walton, N. A., Bailer-Jones, C. A. L., Bastian, U., Cropper, M., Drimmel, R., Katz, D., Soubiran, C., van Leeuwen, F., Audard, M., Bakker, J., Blomme, R., Fabricius, C., Fouesneau, M., Frémat, Y., Galluccio, L., Guerrier, A., Masana, E., Messineo, R., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Roux, W., Seabroke, G. M., Sordo, R., Thévenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Benson, K., Berthier, J., Burgess, P. W., Busonero, D., Busso, G., Cánovas, H., Carry, B., Cheek, N., Clementini, G., Damerdji, Y., de Teodoro, P., Delchambre, L., DellÓro, A., Garcia, E. Fraile, Garabato, D., García-Lario, P., Torres, N. Garralda, Gavras, P., Haigron, R., Hambly, N. C., Harrison, D. L., Hatzidimitriou, D., Hodgkin, S. T., Holl, B., Jamal, S., Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Lorca, A., Marchal, O., Marrese, P. M., Moitinho, A., Muinonen, K., Campos, M. Nuñez, Oreshina-Slezak, I., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Riello, M., Rimoldini, L., Robin, A. C., Roegiers, T., Sarro, L. M., Schultheis, M., Siopis, C., Smith, M., Sozzetti, A., Utrilla, E., van Leeuwen, M., Abbas, U., Ábrahám, P., Aramburu, A. Abreu, Aerts, C., Altavilla, G., Álvarez, M. A., Alves, J., Anders, F., Anderson, R. I., Antoja, T., Baines, D., Baker, S. G., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolomé, S., Bashi, D., Bauchet, N., Baudeau, N., Becciani, U., Bedin, L. R., Bellas-Velidis, I., Bellazzini, M., Beordo, W., Berihuete, A., Bernet, M., Bertolotto, C., Bertone, S., Bianchi, L., Binnenfeld, A., Blazere, A., Boch, T., Bombrun, A., Bouquillon, S., Bragaglia, A., Braine, J., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cannizzo, S., Cantat-Gaudin, T., Carballo, R., Carlucci, T., Carnerero, M. I., Carrasco, J. M., Carretero, J., Carton, S., Casamiquela, L., Castellani, M., Castro-Ginard, A., Cesare, V., Charlot, P., Chemin, L., Chiaramida, V., Chiavassa, A., Chornay, N., Collins, R., Contursi, G., Cooper, W. J., Cornez, T., Crosta, M., Dafonte, C., de Laverny, P., De Luise, F., De March, R., de Souza, R., de Torres, A., del Peloso, E. F., Delbo, M., Delgado, A., Dharmawardena, T. E., Diakite, S., Diener, C., Distefano, E., Dolding, C., Dsilva, K., Durán, J., Enke, H., Esquej, P., Fabre, C., Fabrizio, M., Faigler, S., Fatović, M., Fedorets, G., Fernández-Hernández, J., Fernique, P., Figueras, F., Fournier, Y., Fouron, C., Gai, M., Galinier, M., Garcia-Gutierrez, A., García-Torres, M., Garofalo, A., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., González-Núñez, J., González-Santamaría, I., Gosset, E., Granvik, M., Barrera, V. Gregori, Gutiérrez-Sánchez, R., Haywood, M., Helmer, A., Helmi, A., Henares, K., Hidalgo, S. L., Hilger, T., Hobbs, D., Hottier, C., Huckle, H. E., Jabłońska, M., Jansen, F., Jiménez-Arranz, Ó., Campillo, J. Juaristi, Khanna, S., Kordopatis, G., Kóspál, Á, Kun, M., Lambert, S., Lanza, A. F., Campion, J. -F. Le, Lebreton, Y., Lebzelter, T., Leccia, S., Lecoeur-Taibi, I., Lecoutre, G., Liao, S., Liberato, L., Licata, E., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Loup, C., Mahy, L., Mann, R. G., Manteiga, M., Marchant, J. M., Marconi, M., Pina, D. Marín, Marinoni, S., Marshall, D. J., Lozano, J. Martín, Marton, G., Mary, N., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., McMillan, P. J., Meichsner, J., Messina, S., Michalik, D., Millar, N. R., Molina, D., Molinaro, R., Molnár, L., Monari, G., Monguió, M., Montegriffo, P., Montero, A., Mor, R., Mora, A., Morbidelli, R., Morel, T., Morris, D., Mowlavi, N., Munoz, D., Muraveva, T., Murphy, C. P., Musella, I., Nagy, Z., Nieto, S., Noval, L., Ogden, A., Ordenovic, C., Pagani, C., Pagano, I., Palicio, P. A., Pallas-Quintela, L., Panahi, A., Panem, C., Payne-Wardenaar, S., Pegoraro, L., Penttilä, A., Pesciullesi, P., Piersimoni, A. M., Pinamonti, M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Pourbaix, D., Prša, A., Pulone, L., Racero, E., Rainer, M., Raiteri, C. M., Ramos, P., Ratajczak, M., Fiorentin, P. Re, Regibo, S., Reylé, C., Ripepi, V., Riva, A., Rix, H. -W., Rixon, G., Robichon, N., Robin, C., Romero-Gómez, M., Rowell, N., Royer, F., Rybicki, K. A., Sadowski, G., Núñez, A. Sáez, Sellés, A. Sagristà, Sahlmann, J., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Riera, C. Sarrate, Sciacca, E., Segovia, J. C., Ségransan, D., Shahaf, S., Siebert, A., Siltala, L., Slezak, E., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spina, L., Spitoni, E., Spoto, F., Squillante, L. A., Steele, I. A., Steidelmüller, H., Surdej, J., Szabados, L., Taris, F., Taylor, M. B., Teixeira, R., Tolomei, L., Elipe, G. Torralba, Trabucchi, M., Tsantaki, M., Ulla, A., Unger, N., Vanel, O., Vecchiato, A., Vicente, D., Voutsinas, S., Weiler, M., Wyrzykowski, Ł., Zhao, H., Zorec, J., Zwitter, T., Balaguer-Núñez, L., Leclerc, N., Morgenthaler, S., Robert, G., and Zucker, S.

Subjects
Astrophysics - Solar and Stellar Astrophysics, Astrophysics - Astrophysics of Galaxies
Abstract

Gaia's readout window strategy is challenged by very dense fields in the sky. Therefore, in addition to standard Gaia observations, full Sky Mapper (SM) images were recorded for nine selected regions in the sky. A new software pipeline exploits these Service Interface Function (SIF) images of crowded fields (CFs), making use of the availability of the full two-dimensional (2D) information. This new pipeline produced half a million additional Gaia sources in the region of the omega Centauri ($\omega$ Cen) cluster, which are published with this Focused Product Release. We discuss the dedicated SIF CF data reduction pipeline, validate its data products, and introduce their Gaia archive table. Our aim is to improve the completeness of the {\it Gaia} source inventory in a very dense region in the sky, $\omega$ Cen. An adapted version of {\it Gaia}'s Source Detection and Image Parameter Determination software located sources in the 2D SIF CF images. We validated the results by comparing them to the public {\it Gaia} DR3 catalogue and external Hubble Space Telescope data. With this Focused Product Release, 526\,587 new sources have been added to the {\it Gaia} catalogue in $\omega$ Cen. Apart from positions and brightnesses, the additional catalogue contains parallaxes and proper motions, but no meaningful colour information. While SIF CF source parameters generally have a lower precision than nominal {\it Gaia} sources, in the cluster centre they increase the depth of the combined catalogue by three magnitudes and improve the source density by a factor of ten. This first SIF CF data publication already adds great value to the {\it Gaia} catalogue. It demonstrates what to expect for the fourth {\it Gaia} catalogue, which will contain additional sources for all nine SIF CF regions.

Published
2023
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21. Gaia Focused Product Release: A catalogue of sources around quasars to search for strongly lensed quasars

Author

Gaia Collaboration, Krone-Martins, A., Ducourant, C., Galluccio, L., Delchambre, L., Oreshina-Slezak, I., Teixeira, R., Braine, J., Campion, J. -F. Le, Mignard, F., Roux, W., Blazere, A., Pegoraro, L., Brown, A. G. A., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Arenou, F., Babusiaux, C., Barbier, A., Biermann, M., Creevey, O. L., Evans, D. W., Eyer, L., Guerra, R., Hutton, A., Jordi, C., Klioner, S. A., Lammers, U., Lindegren, L., Luri, X., Randich, S., Sartoretti, P., Smiljanic, R., Tanga, P., Walton, N. A., Bailer-Jones, C. A. L., Bastian, U., Cropper, M., Drimmel, R., Katz, D., Soubiran, C., van Leeuwen, F., Audard, M., Bakker, J., Blomme, R., Castaneda, J., De Angeli, F., Fabricius, C., Fouesneau, M., Fremat, Y., Guerrier, A., Masana, E., Messineo, R., Nicolas, C., Nienartowicz, K., Pailler, F., Panuzzo, P., Riclet, F., Seabroke, G. M., Sordo, R., Thevenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Benson, K., Berthier, J., Burgess, P. W., Busonero, D., Busso, G., Canovas, H., Carry, B., Cheek, N., Clementini, G., Damerdji, Y., Davidson, M., de Teodoro, P., Dell'Oro, A., Garcia, E. Fraile, Garabato, D., Garcia-Lario, P., Torres, N. Garralda, Gavras, P., Haigron, R., Hambly, N. C., Harrison, D. L., Hatzidimitriou, D., Hernandez, J., Hodgkin, S. T., Holl, B., Jamal, S., Jordan, S., Lanzafame, A. C., Loffler, W., Lorca, A., Marchal, O., Marrese, P. M., Moitinho, A., Muinonen, K., Campos, M. Nunez, Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Riello, M., Rimoldini, L., Robin, A. C., Roegiers, T., Sarro, L. M., Schultheis, M., Siopis, C., Smith, M., Sozzetti, A., Utrilla, E., van Leeuwen, M., Weingrill, K., Abbas, U., Abraham, P., Aramburu, A. Abreu, Aerts, C., Altavilla, G., Alvarez, M. A., Alves, J., Anderson, R. I., Antoja, T., Baines, D., Baker, S. G., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolome, S., Bashi, D., Bauchet, N., Baudeau, N., Becciani, U., Bedin, L. R., Bellas-Velidis, I., Bellazzini, M., Beordo, W., Berihuete, A., Bernet, M., Bertolotto, C., Bertone, S., Bianchi, L., Binnenfeld, A., Boch, T., Bombrun, A., Bouquillon, S., Bragaglia, A., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cannizzo, S., Carballo, R., Carlucci, T., Carnerero, M. I., Carrasco, J. M., Carretero, J., Carton, S., Casamiquela, L., Castellani, M., Castro-Ginard, A., Cesare, V., Charlot, P., Chemin, L., Chiaramida, V., Chiavassa, A., Chornay, N., Collins, R., Contursi, G., Cooper, W. J., Cornez, T., Crosta, M., Crowley, C., Dafonte, C., de Laverny, P., De Luise, F., De March, R., de Souza, R., de Torres, A., del Peloso, E. F., Delbo, M., Delgado, A., Dharmawardena, T. E., Diakite, S., Diener, C., Distefano, E., Dolding, C., Dsilva, K., Duran, J., Enke, H., Esquej, P., Fabre, C., Fabrizio, M., Faigler, S., Fatovic, M., Fedorets, G., Fernandez-Hernandez, J., Fernique, P., Figueras, F., Fournier, Y., Fouron, C., Gai, M., Galinier, M., Garcia-Gutierrez, A., Garcia-Torres, M., Garofalo, A., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., Gonzalez-Nunez, J., Gonzalez-Santamaria, I., Gosset, E., Granvik, M., Barrera, V. Gregori, Gutierrez-Sanchez, R., Haywood, M., Helmer, A., Helmi, A., Henares, K., Hidalgo, S. L., Hilger, T., Hobbs, D., Hottier, C., Huckle, H. E., Jablonska, M., Jansen, F., Jimenez-Arranz, O., Campillo, J. Juaristi, Khanna, S., Kordopatis, G., Kospal, A., Kostrzewa-Rutkowska, Z., Kun, M., Lambert, S., Lanza, A. F., Lebreton, Y., Lebzelter, T., Leccia, S., Lecoeur-Taibi, I., Lecoutre, G., Liao, S., Liberato, L., Licata, E., Lindstrom, H. E. P., Lister, T. A., Livanou, E., Lobel, A., Loup, C., Mahy, L., Mann, R. G., Manteiga, M., Marchant, J. M., Marconi, M., Pina, D. Marin, Marinoni, S., Marshall, D. J., Lozano, J. Martin, Martin-Fleitas, J. M., Marton, G., Mary, N., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., McMillan, P. J., Meichsner, J., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnar, L., Monari, G., Monguio, M., Montegriffo, P., Montero, A., Mor, R., Mora, A., Morbidelli, R., Morel, T., Morris, D., Mowlavi, N., Munoz, D., Muraveva, T., Murphy, C. P., Musella, I., Nagy, Z., Nieto, S., Noval, L., Ogden, A., Ordenovic, C., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Pallas-Quintela, L., Panahi, A., Panem, C., Payne-Wardenaar, S., Penttila, A., Pesciullesi, P., Piersimoni, A. M., Pinamonti, M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Pourbaix, D., Prsa, A., Pulone, L., Racero, E., Rainer, M., Raiteri, C. M., Ramos, P., Ramos-Lerate, M., Ratajczak, M., Fiorentin, P. Re, Regibo, S., Reyle, C., Ripepi, V., Riva, A., Rix, H. -W., Rixon, G., Robichon, N., Robin, C., Romero-Gomez, M., Rowell, N., Royer, F., Mieres, D. Ruz, Rybicki, K. A., Sadowski, G., Nunez, A. Saez, Selles, A. Sagrista, Sahlmann, J., Gimenez, V. Sanchez, Sanna, N., Santovena, R., Sarasso, M., Riera, C. Sarrate, Sciacca, E., Segovia, J. C., Segransan, D., Shahaf, S., Siebert, A., Siltala, L., Slezak, E., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spina, L., Spitoni, E., Spoto, F., Squillante, L. A., Steele, I. A., Steidelmuller, H., Surdej, J., Szabados, L., Taris, F., Taylor, M. B., Tisanic, K., Tolomei, L., Torra, F., Elipe, G. Torralba, Trabucchi, M., Tsantaki, M., Ulla, A., Unger, N., Vanel, O., Vecchiato, A., Vicente, D., Voutsinas, S., Weiler, M., Wyrzykowski, L., Zhao, H., Zorec, J., Zwitter, T., Balaguer-Nunez, L., Leclerc, N., Morgenthaler, S., Robert, G., and Zucker, S.

Subjects
Astrophysics - Astrophysics of Galaxies, Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

Context. Strongly lensed quasars are fundamental sources for cosmology. The Gaia space mission covers the entire sky with the unprecedented resolution of $0.18$" in the optical, making it an ideal instrument to search for gravitational lenses down to the limiting magnitude of 21. Nevertheless, the previous Gaia Data Releases are known to be incomplete for small angular separations such as those expected for most lenses. Aims. We present the Data Processing and Analysis Consortium GravLens pipeline, which was built to analyse all Gaia detections around quasars and to cluster them into sources, thus producing a catalogue of secondary sources around each quasar. We analysed the resulting catalogue to produce scores that indicate source configurations that are compatible with strongly lensed quasars. Methods. GravLens uses the DBSCAN unsupervised clustering algorithm to detect sources around quasars. The resulting catalogue of multiplets is then analysed with several methods to identify potential gravitational lenses. We developed and applied an outlier scoring method, a comparison between the average BP and RP spectra of the components, and we also used an extremely randomised tree algorithm. These methods produce scores to identify the most probable configurations and to establish a list of lens candidates. Results. We analysed the environment of 3 760 032 quasars. A total of 4 760 920 sources, including the quasars, were found within 6" of the quasar positions. This list is given in the Gaia archive. In 87\% of cases, the quasar remains a single source, and in 501 385 cases neighbouring sources were detected. We propose a list of 381 lensed candidates, of which we identified 49 as the most promising. Beyond these candidates, the associate tables in this Focused Product Release allow the entire community to explore the unique Gaia data for strong lensing studies further., Comment: 35 pages, 60 figures, accepted for publication by Astronomy and Astrophysics

Published
2023
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22. Gaia Focused Product Release: Radial velocity time series of long-period variables

Author

Gaia Collaboration, Trabucchi, M., Mowlavi, N., Lebzelter, T., Lecoeur-Taibi, I., Audard, M., Eyer, L., García-Lario, P., Gavras, P., Holl, B., de Fombelle, G. Jevardat, Nienartowicz, K., Rimoldini, L., Sartoretti, P., Blomme, R., Frémat, Y., Marchal, O., Damerdji, Y., Brown, A. G. A., Guerrier, A., Panuzzo, P., Katz, D., Seabroke, G. M., Benson, K., Haigron, R., Smith, M., Lobel, A., Vallenari, A., Prusti, T., de Bruijne, J. H. J., Arenou, F., Babusiaux, C., Barbier, A., Biermann, M., Creevey, O. L., Ducourant, C., Evans, D. W., Guerra, R., Hutton, A., Jordi, C., Klioner, S. A., Lammers, U., Lindegren, L., Luri, X., Mignard, F., Randich, S., Smiljanic, R., Tanga, P., Walton, N. A., Bailer-Jones, C. A. L., Bastian, U., Cropper, M., Drimmel, R., Lattanzi, M. G., Soubiran, C., van Leeuwen, F., Bakker, J., Castañeda, J., De Angeli, F., Fabricius, C., Fouesneau, M., Galluccio, L., Masana, E., Messineo, R., Nicolas, C., Pailler, F., Riclet, F., Roux, W., Sordo, R., Thévenin, F., Gracia-Abril, G., Portell, J., Teyssier, D., Altmann, M., Berthier, J., Burgess, P. W., Busonero, D., Busso, G., Cánovas, H., Carry, B., Cheek, N., Clementini, G., Davidson, M., de Teodoro, P., Delchambre, L., Dell'Oro, A., Garcia, E. Fraile, Garabato, D., Torres, N. Garralda, Hambly, N. C., Harrison, D. L., Hatzidimitriou, D., Hernández, J., Hodgkin, S. T., Jamal, S., Jordan, S., Krone-Martins, A., Lanzafame, A. C., Löffler, W., Lorca, A., Marrese, P. M., Moitinho, A., Muinonen, K., Campos, M. Nuñez, Oreshina-Slezak, I., Osborne, P., Pancino, E., Pauwels, T., Recio-Blanco, A., Riello, M., Robin, A. C., Roegiers, T., Sarro, L. M., Schultheis, M., Siopis, C., Sozzetti, A., Utrilla, E., van Leeuwen, M., Weingrill, K., Abbas, U., Ábrahám, P., Aramburu, A. Abreu, Aerts, C., Altavilla, G., Álvarez, M. A., Alves, J., Anders, F., Anderson, R. I., Antoja, T., Baines, D., Baker, S. G., Balog, Z., Barache, C., Barbato, D., Barros, M., Barstow, M. A., Bartolomé, S., Bashi, D., Bauchet, N., Baudeau, N., Becciani, U., Bedin, L. R., Bellas-Velidis, I., Bellazzini, M., Beordo, W., Berihuete, A., Bernet, M., Bertolotto, C., Bertone, S., Bianchi, L., Binnenfeld, A., Blazere, A., Boch, T., Bombrun, A., Bouquillon, S., Bragaglia, A., Braine, J., Bramante, L., Breedt, E., Bressan, A., Brouillet, N., Brugaletta, E., Bucciarelli, B., Butkevich, A. G., Buzzi, R., Caffau, E., Cancelliere, R., Cannizzo, S., Carballo, R., Carlucci, T., Carnerero, M. I., Carrasco, J. M., Carretero, J., Carton, S., Casamiquela, L., Castellani, M., Castro-Ginard, A., Cesare, V., Charlot, P., Chemin, L., Chiaramida, V., Chiavassa, A., Chornay, N., Collins, R., Contursi, G., Cooper, W. J., Cornez, T., Crosta, M., Crowley, C., Dafonte, C., David, M., de Laverny, P., De Luise, F., De March, R., De Ridder, J., de Souza, R., de Torres, A., del Peloso, E. F., Delbo, M., Delgado, A., Dharmawardena, T. E., Diakite, S., Diener, C., Distefano, E., Dolding, C., Dsilva, K., Durán, J., Enke, H., Esquej, P., Fabre, C., Fabrizio, M., Faigler, S., Fatović, M., Fedorets, G., Fernández-Hernández, J., Fernique, P., Figueras, F., Fournier, Y., Fouron, C., Gai, M., Galinier, M., Garcia-Gutierrez, A., García-Torres, M., Garofalo, A., Gerlach, E., Geyer, R., Giacobbe, P., Gilmore, G., Girona, S., Giuffrida, G., Gomel, R., Gomez, A., González-Núñez, J., González-Santamaría, I., Gosset, E., Granvik, M., Barrera, V. Gregori, Gutiérrez-Sánchez, R., Haywood, M., Helmer, A., Helmi, A., Henares, K., Hidalgo, S. L., Hilger, T., Hobbs, D., Hottier, C., Huckle, H. E., Jabłońska, M., Jansen, F., Jiménez-Arranz, Ó., Campillo, J. Juaristi, Khanna, S., Kordopatis, G., Kóspál, Á, Kostrzewa-Rutkowska, Z., Kun, M., Lambert, S., Lanza, A. F., Campion, J. -F. Le, Lebreton, Y., Leccia, S., Lecoutre, G., Liao, S., Liberato, L., Licata, E., Lindstrøm, H. E. P., Lister, T. A., Livanou, E., Loup, C., Mahy, L., Mann, R. G., Manteiga, M., Marchant, J. M., Marconi, M., Pina, D. Marín, Marinoni, S., Marshall, D. J., Lozano, J. Martín, Martín-Fleitas, J. M., Marton, G., Mary, N., Masip, A., Massari, D., Mastrobuono-Battisti, A., Mazeh, T., McMillan, P. J., Meichsner, J., Messina, S., Michalik, D., Millar, N. R., Mints, A., Molina, D., Molinaro, R., Molnár, L., Monari, G., Monguió, M., Montegriffo, P., Montero, A., Mor, R., Mora, A., Morbidelli, R., Morel, T., Morris, D., Munoz, D., Muraveva, T., Murphy, C. P., Musella, I., Nagy, Z., Nieto, S., Noval, L., Ogden, A., Ordenovic, C., Pagani, C., Pagano, I., Palaversa, L., Palicio, P. A., Pallas-Quintela, L., Panahi, A., Panem, C., Payne-Wardenaar, S., Pegoraro, L., Penttilä, A., Pesciullesi, P., Piersimoni, A. M., Pinamonti, M., Pineau, F. -X., Plachy, E., Plum, G., Poggio, E., Pourbaix, D., Prša, A., Pulone, L., Racero, E., Rainer, M., Raiteri, C. M., Ramos, P., Ramos-Lerate, M., Ratajczak, M., Fiorentin, P. Re, Regibo, S., Reylé, C., Ripepi, V., Riva, A., Rix, H. -W., Rixon, G., Robichon, N., Robin, C., Romero-Gómez, M., Rowell, N., Royer, F., Mieres, D. Ruz, Rybicki, K. A., Sadowski, G., Núñez, A. Sáez, Sellés, A. Sagristà, Sahlmann, J., Gimenez, V. Sanchez, Sanna, N., Santoveña, R., Sarasso, M., Riera, C. Sarrate, Sciacca, E., Segovia, J. C., Ségransan, D., Shahaf, S., Siebert, A., Siltala, L., Slezak, E., Smart, R. L., Snaith, O. N., Solano, E., Solitro, F., Souami, D., Souchay, J., Spina, L., Spitoni, E., Spoto, F., Squillante, L. A., Steele, I. A., Steidelmüller, H., Surdej, J., Szabados, L., Taris, F., Taylor, M. B., Teixeira, R., Tisanić, K., Tolomei, L., Torra, F., Elipe, G. Torralba, Tsantaki, M., Ulla, A., Unger, N., Vanel, O., Vecchiato, A., Vicente, D., Voutsinas, S., Weiler, M., Wyrzykowski, Ł., Zhao, H., Zorec, J., Zwitter, T., Balaguer-Núñez, L., Leclerc, N., Morgenthaler, S., Robert, G., and Zucker, S.

Subjects
Astrophysics - Solar and Stellar Astrophysics
Abstract

The third Gaia Data Release (DR3) provided photometric time series of more than 2 million long-period variable (LPV) candidates. Anticipating the publication of full radial-velocity (RV) in DR4, this Focused Product Release (FPR) provides RV time series for a selection of LPVs with high-quality observations. We describe the production and content of the Gaia catalog of LPV RV time series, and the methods used to compute variability parameters published in the Gaia FPR. Starting from the DR3 LPVs catalog, we applied filters to construct a sample of sources with high-quality RV measurements. We modeled their RV and photometric time series to derive their periods and amplitudes, and further refined the sample by requiring compatibility between the RV period and at least one of the $G$, $G_{\rm BP}$, or $G_{\rm RP}$ photometric periods. The catalog includes RV time series and variability parameters for 9\,614 sources in the magnitude range $6\lesssim G/{\rm mag}\lesssim 14$, including a flagged top-quality subsample of 6\,093 stars whose RV periods are fully compatible with the values derived from the $G$, $G_{\rm BP}$, and $G_{\rm RP}$ photometric time series. The RV time series contain a mean of 24 measurements per source taken unevenly over a duration of about three years. We identify the great most sources (88%) as genuine LPVs, with about half of them showing a pulsation period and the other half displaying a long secondary period. The remaining 12% consists of candidate ellipsoidal binaries. Quality checks against RVs available in the literature show excellent agreement. We provide illustrative examples and cautionary remarks. The publication of RV time series for almost 10\,000 LPVs constitutes, by far, the largest such database available to date in the literature. The availability of simultaneous photometric measurements gives a unique added value to the Gaia catalog (abridged), Comment: 36 pages, 38 figures

Published
2023

23. Exploring Chemical and Cultural Weed Management for Industrial Hemp Production in Georgia, USA

Author

Hannah E. Wright-Smith, Timothy W. Coolong, A. Stanley Culpepper, Taylor M. Randell-Singleton, and Jenna C. Vance

Subjects
Cannabis sativa, hand transplant, herbicide screening, mechanical transplanter, plastic mulch, Agriculture, Chemical technology, TP1-1185
Abstract

Industrial hemp (Cannabis sativa) production is complex, with strict regulatory constraints and challenges associated with a lack of labeled pesticides due to its status as a novel crop in the US. Four experiments were conducted in 2020 and 2021 to establish herbicide tolerances for hemp production in the coastal plain of Georgia, USA. Objectives included evaluating hemp response to pretransplant or posttransplant herbicides, determining if planting method influenced herbicide injury from residual preplant applied herbicides, and understanding how plastic mulch may influence hemp flower yields. When applied one day prior to transplanting, maximum hemp crop visual injury was less than 12% compared to the untreated control, with acetochlor, flumioxazin, fomesafen, pendimethalin, and norflurazon while dithiopyr, halosulfuron, isoxaben, and isoxaflutole resulted in greater than 50% injury. Posttransplant applications of S-metolachlor, acetochlor, pendimethalin, and clethodim resulted in less than 15% injury while halosulfuron, metribuzin, trifloxysulfuron, imazethapyr, and prometryn applications resulted in greater than 50% injury to plants. Preplant and posttransplant applied herbicides were found to have little effect on total tetrahydrocannabinol (THC), cannabidiol (CBD), or total cannabinoids in the dry flower after harvest. In a separate experiment, injury from halosulfuron and metribuzin was 52% to 56% less when planted with a mechanical transplanter as compared to the practice of using a transplant wheel to depress a hole in the soil followed by hand transplanting. In the final experiment, hemp dry flower yield in a non-plastic mulched (bareground) system was similar to that in a plastic mulched system. However, early season plant above-ground biomass was less in the plastic mulched system, which may have been due to elevated soil temperatures inhibiting early season growth.

Published
2024
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24. Impact of COVID-19 Stress on Food Insecurity and Fruit and Vegetable Consumption among College Students

Author

Taylor M. Levy, Ronald D. Williams, Mary Odum, Jeff M. Housman, and Jacquelyn D. McDonald

Abstract

Objective: This cross-sectional study utilized structural equation modeling to examine effects of COVID-19 stress on food insecurity and fruit and vegetable consumption mediated through personal agency and behavioral intention. Participants: Students (n = 749) enrolled at one federally designated Hispanic-serving public university during the fall 2020 semester. Methods: A 34-item survey was developed and administered. Results: COVID-19 stress had a statistically significant impact on food insecurity (B = 0.341; p < 0.001) and an inverse impact on personal agency to consume fruit and vegetables (B = -0.283; p < 0.001). Personal agency (B = 0.389; p < 0.001) and behavioral intention to consume fruit and vegetables were directly associated while food insecurity inversely impacted behavioral intention (B = -0.076; p = 0.034). Conclusions: Pandemic-related stress impacts nutrition behaviors among the student population already at risk of poor fruit and vegetable intake. During periods of high pandemic-related stress, college students need adequate access to fruits and vegetables and health promotion programs emphasizing stress management and healthy dietary behaviors.

Published
2024
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25. Illness Uncertainty and Intrusiveness in Adolescent and Young Adult Women with Self-Reported Chronic Migraines

Author

Alexandra M. DeLone, Taylor M. Dattilo, Caroline M. Roberts, Rachel S. Fisher, John M. Chaney, and Larry L. Mullins

Abstract

Background: Chronic migraines result in debilitating pain requiring complex and multifaceted daily management, including acting purposefully to attenuate symptoms and decrease impairment. Experiencing migraines may be more psychologically challenging for adolescent and young adult (AYA) women due to complex and recurrent stressors. Purpose: This study examined the relationships between illness specific cognitive appraisal mechanisms (i.e., illness uncertainty and illness intrusiveness) and psychological adjustment (i.e., anxious and depressive symptoms) in AYA women with self-reported chronic migraines. Methods: AYA women (N = 74, M[subscript age] = 20.19, SD = 3.41) with chronic migraines completed measures of illness uncertainty, illness intrusiveness, anxious, and depressive symptoms. Results: Two hierarchical regression analyses indicated that illness uncertainty (B = 0.44, p < 0.001) and intrusiveness (B = 0.27, p = 0.026) significantly predicted anxious, F(4, 68) = 12.83, p < 0.001, and depressive symptoms, F(4, 68) = 8.48, p < 0.001, B = 0.31, p = 0.021 and B = 0.27, p = 0.037. Discussion: Greater illness uncertainty and illness intrusiveness were associated with greater anxious and depressive symptoms. Thus, it may be that AYA women who experience chronic migraines have increased perceptions of ambiguity, unpredictability, and disruption to their life that significantly contribute to their psychological adjustment outcomes. Translation to Health Education Practice: This study demonstrates a need for health education on the role of illness related cognitive appraisal mechanisms for AYA women with chronic migraines.

Published
2024
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26. Development and Cognitive Testing of Occupational Safety and Health Questions for a Youth Survey: Addressing the Research Needs for a Vulnerable Working Population

Author

Taylor M. Shockey, Sharon R. Silver, and Amanda Wilmot

Abstract

Background: While more than 2.5 million U.S. high students worked in 2020, data to assess how work affects this group are sparse. To facilitate such research, a set of occupational safety and health questions for inclusion on the Youth Risk Behavior Surveillance System (YRBSS) and other youth-focused surveys was developed. Methods: Survey questions about occupational experiences of young workers were adapted from other surveys or created de novo. Key audiences were engaged to define priority topic areas and develop draft questions, which were further refined through cognitive interviews with working youth. Results: Twenty-one resulting questions spanned multiple work-related topics: employment status; health outcomes; psychosocial exposures; and safety climate. Cognitive testing revealed that youth (aged 14-19) had difficulty with temporal concepts. Some difficulties reflected the propensity of youth to engage in multiple, online, and informal jobs. During 3 rounds of interviews, questions were adjusted to better reflect youth employment circumstances and language. Four states added at least 1 work-related question to their 2023 Youth Risk Behavior Survey questionnaire, and the full set of questions has been disseminated to federal agencies and partners. Conclusion: Including tailored questions about employment in surveys of youth will facilitate occupational health surveillance for this group. Analysis of resulting data can help to close knowledge gaps, provide current prevalence data, inform policy, and allow development of focused prevention and intervention strategies to reduce adverse outcomes among young workers.

Published
2024
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27. More Laws for Pauses: Replication and Generalization

Author

Taylor M. Mezaraups and David L. Gilden

Abstract

The basic timescales governing animal life are generally determined by body size. Pauses in naturally occurring human speech were investigated to determine if pause timescales are also sensitive to body size. Reported is an analysis of pause duration allometry in recorded interviews of 61 athletes. Pauses were divided into three classes based on whether they occurred during fluid speech or whether they preceded or followed a filled pause (i.e., "um"). Allometric laws relating body size to pause size were found for all three classes--larger people take longer pauses. The derived allometric exponents were used to evaluate a theory of how people experience the passage of time. The theory associates the experience of time passage with the distal flow of time through the mathematics of bounded exponential growth. Nonlinearities inherent in the theory are shown to predict, in detail, the way body size interacts with linguistic context in the deployment of pauses. The theory provides a meaningful framework for understanding how time is experienced as a felt quantity and how pauses are negotiated in everyday speech.

Published
2024
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28. The impact of attending historically Black colleges and universities on cognitive decline in Black adults: A longitudinal analysis in the KHANDLE and STAR cohorts

Author

Thomas, Marilyn D, Calmasini, Camilla, Khela, Harmon, Mobley, Taylor M, Mayeda, Elizabeth Rose, Mangurian, Christina, Barnes, Lisa L, Gilsanz, Paola, Whitmer, Rachel A, and Glymour, M Maria

Subjects
Biomedical and Clinical Sciences, Biological Psychology, Clinical Sciences, Neurosciences, Psychology, Clinical Research, Acquired Cognitive Impairment, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Alzheimer's Disease, Brain Disorders, Neurodegenerative, Basic Behavioral and Social Science, Behavioral and Social Science, Dementia, Aging, Good Health and Well Being, Humans, Adult, Aged, Universities, Healthy Aging, Life Change Events, Cognitive Dysfunction, Black, cognition, cognitive decline, college, executive function, historically Black colleges and universities, university, verbal episodic memory, Geriatrics, Clinical sciences, Biological psychology
Abstract

IntroductionBlack students attending predominantly White institutions (PWIs) versus historically Black colleges and universities (HBCUs) report more harmful discrimination and develop worse mental health outcomes, potentially offsetting the established benefits of college for lowering dementia incidence.MethodsBlack participants in two cohorts (the Kaiser Healthy Aging and Diverse Life Experiences [KHANDLE] and the Study of Healthy Aging in African Americans [STAR]) who had attended college (N = 716) self-reported the college name (classified as HBCU vs. PWI) and completed three waves of executive function (EF) and verbal episodic memory (VEM) assessments. HBCU effects on cognitive level and decline were estimated using adjusted linear mixed-effects models.ResultsHBCU (vs. PWI) attendees averaged better EF (β = 0.05 [-0.22, 0.32]) and VEM (β = 0.21 [-0.06, 0.46]) at age 70 though neither association was statistically significant. HBCU attendance was associated with slightly faster VEM decline (β = -0.03 [-0.05, 0.00]).DiscussionHarmonized analyses with larger studies are needed to estimate important effects of HBCU attendance.HighlightsHigher education is robustly linked to lower dementia risk, yet Black-White inequities persist among college-educated adults. Black students attending predominantly White institutions (PWIs) versus historically Black colleges and universities (HBCUs) report more harmful discrimination and develop worse mental health outcomes, which may offset the established benefits of college for lowering dementia incidence. HBCU (vs. non-HBCU) attendees averaged better executive function and verbal episodic memory (VEM) at average age 70, though confidence intervals were wide and associations were not statistically significant, and averaged slightly faster decline in VEM. Harmonized analyses using larger nationally representative studies are likely needed to avoid underestimating the health effects of HBCU attendance.

Published
2023

29. An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders

Author

Dorion, Marie-France, Casas, Diana, Shlaifer, Irina, Yaqubi, Moein, Fleming, Peter, Karpilovsky, Nathan, Chen, Carol X.-Q., Nicouleau, Michael, Piscopo, Valerio E. C., MacDougall, Emma J., Alluli, Aeshah, Goldsmith, Taylor M., Schneider, Alexandria, Dorion, Samuel, Aprahamian, Nathalia, MacDonald, Adam, Thomas, Rhalena A., Dudley, Roy W. R., Hall, Jeffrey A., Fon, Edward A., Antel, Jack P., Stratton, Jo Anne, Durcan, Thomas M., La Piana, Roberta, and Healy, Luke M.

Published
2024
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34. The Present and Future of QCD

Author

Achenbach, P., Adhikari, D., Afanasev, A., Afzal, F., Aidala, C. A., Al-bataineh, A., Almaalol, D. K., Amaryan, M., Androić, D., Armstrong, W. R., Arratia, M., Arrington, J., Asaturyan, A., Aschenauer, E. C., Atac, H., Avakian, H., Averett, T., Gayoso, C. Ayerbe, Bai, X., Barish, K. N., Barnea, N., Basar, G., Battaglieri, M., Baty, A. A., Bautista, I., Bazilevsky, A., Beattie, C., Behera, S. C., Bellini, V., Bellwied, R., Benesch, J. F., Benmokhtar, F., Bernardes, C. A., Bernauer, J. C., Bhatt, H., Bhatta, S., Boer, M., Boettcher, T. J., Bogacz, S. A., Bossi, H. J., Brandenburg, J. D., Brash, E. J., Briceño, R. A., Briscoe, W. J., Brodsky, S. J., Brown, D. A., Burkert, V. D., Caines, H., Cali, I. A., Camsonne, A., Carman, D. S., Caylor, J., Cerci, S., Llatas, M. Chamizo, Chatterjee, S., Chen, J. P., Chen, Y., Chen, Y. -C., Chien, Y. -T., Chou, P. -C., Chu, X., Chudakov, E., Cline, E., Cloët, I. C., Cole, P. L., Connors, M. E., Constantinou, M., Cosyn, W., Dusa, S. Covrig, Cruz-Torres, R., D'Alesio, U., da Silva, C., Davoudi, Z., Dean, C. T., Dean, D. J., Demarteau, M., Deshpande, A., Detmold, W., Deur, A., Devkota, B. R., Dhital, S., Diefenthaler, M., Dobbs, S., Döring, M., Dong, X., Dotel, R., Dow, K. A., Downie, E. J., Drachenberg, J. L., Dumitru, A., Dunlop, J. C., Dupre, R., Durham, J. M., Dutta, D., Edwards, R. G., Ehlers, R. J., Fassi, L. El, Elaasar, M., Elouadrhiri, L., Engelhardt, M., Ent, R., Esumi, S., Evdokimov, O., Eyser, O., Fanelli, C., Fatemi, R., Fernando, I. P., Flor, F. A., Fomin, N., Frawley, A. D., Frederico, T., Fries, R. J., Gal, C., Gamage, B. R., Gamberg, L., Gao, H., Gaskell, D., Geurts, F., Ghandilyan, Y., Ghimire, N., Gilman, R., Gleason, C., Gnanvo, K., Gothe, R. W., Greene, S. V., Grießhammer, H. W., Grossberndt, S. K., Grube, B., Hackett, D. C., Hague, T. J., Hakobyan, H., Hansen, J. -O., Hatta, Y., Hattawy, M., Havener, L. B., Hen, O., Henry, W., Higinbotham, D. W., Hobbs, T. J., Hodges, A. M., Holmstrom, T., Hong, B., Horn, T., Howell, C. R., Huang, H. Z., Huang, M., Huang, S., Huber, G. M., Hyde, C. E., Isupov, E. L., Jacobs, P. M., Jalilian-Marian, J., Jentsch, A., Jheng, H., Ji, C. -R., Ji, X., Jia, J., Jones, D. C., Jones, M. K., Kalantarians, N., Kalicy, G., Kang, Z. B., Karthein, J. M., Keller, D., Keppel, C., Khachatryan, V., Kharzeev, D. E., Kim, H., Kim, M., Kim, Y., King, P. M., Kinney, E., Klein, S. R., Ko, H. S., Koch, V., Kohl, M., Kovchegov, Y. V., Krintiras, G. K., Kubarovsky, V., Kuhn, S. E., Kumar, K. S., Kutz, T., Lajoie, J. G., Lauret, J., Lavrukhin, I., Lawrence, D., Lee, J. H., Lee, K., Lee, S., Lee, Y. -J., Li, S., Li, W., Li, Xiaqing, Li, Xuan, Liao, J., Lin, H. -W., Lisa, M. A., Liu, K. -F., Liu, M. X., Liu, T., Liuti, S., Liyanage, N., Llope, W. J., Loizides, C., Longo, R., Lorenzon, W., Lunkenheimer, S., Luo, X., Ma, R., McKinnon, B., Meekins, D. G., Mehtar-Tani, Y., Melnitchouk, W., Metz, A., Meyer, C. A., Meziani, Z. -E., Michaels, R., Michel, J. K. L., Milner, R. G., Mkrtchyan, H., Mohanmurthy, P., Mohanty, B., Mokeev, V. I., Moon, D. H., Mooney, I. A., Morningstar, C., Morrison, D. P., Müller, B., Mukherjee, S., Mulligan, J., Camacho, C. Munoz, Quijada, J. A. Murillo, Murray, M. J., Nadeeshani, S. A., Nadel-Turonski, P., Nam, J. D., Nattrass, C. E., Nijs, G., Noronha, J., Noronha-Hostler, J., Novitzky, N., Nycz, M., Olness, F. I., Osborn, J. D., Pak, R., Pandey, B., Paolone, M., Papandreou, Z., Paquet, J. -F., Park, S., Paschke, K. D., Pasquini, B., Pasyuk, E., Patel, T., Patton, A., Paudel, C., Peng, C., Peng, J. C., Da Costa, H. Pereira, Perepelitsa, D. V., Peters, M. J., Petreczky, P., Pisarski, R. D., Pitonyak, D., Ploskon, M. A., Posik, M., Poudel, J., Pradhan, R., Prokudin, A., Pruneau, C. A., Puckett, A. J. R., Pujahari, P., Putschke, J., Pybus, J. R., Qiu, J. -W., Rajagopal, K., Ratti, C., Read, K. F., Reed, R., Richards, D. G., Riedl, C., Ringer, F., Rinn, T., West, J. Rittenhouse, Roche, J., Rodas, A., Roland, G., Romero-López, F., Rossi, P., Rostomyan, T., Ruan, L., Ruimi, O. M., Saha, N. R., Sahoo, N. R., Sakaguchi, T., Salazar, F., Salgado, C. W., Salmè, G., Salur, S., Santiesteban, S. N., Sargsian, M. M., Sarsour, M., Sato, N., Satogata, T., Sawada, S., Schäfer, T., Scheihing-Hitschfeld, B., Schenke, B., Schindler, S. T., Schmidt, A., Seidl, R., Shabestari, M. H., Shanahan, P. E., Shen, C., Sheng, T. -A., Shepherd, M. R., Sickles, A. M., Sievert, M. D., Smith, K. L., Song, Y., Sorensen, A., Souder, P. A., Sparveris, N., Srednyak, S., Leiton, A. G. Stahl, Stasto, A. M., Steinberg, P., Stepanyan, S., Stephanov, M., Stevens, J. R., Stewart, D. J., Stewart, I. W., Stojanovic, M., Strakovsky, I., Strauch, S., Strickland, M., Cerci, D. Sunar, Suresh, M., Surrow, B., Syritsyn, S., Szczepaniak, A. P., Tadepalli, A. S., Tang, A. H., Takaki, J. D. Tapia, Tarnowsky, T. J., Tawfik, A. N., Taylor, M. I., Tennant, C., Thiel, A., Thomas, D., Tian, Y., Timmins, A. R., Tribedy, P., Tu, Z., Tuo, S., Ullrich, T., Umaka, E., Upton, D. W., Vary, J. P., Velkovska, J., Venugopalan, R., Vijayakumar, A., Vitev, I., Vogelsang, W., Vogt, R., Vossen, A., Voutier, E., Vovchenko, V., Walker-Loud, A., Wang, F., Wang, J., Wang, X., Wang, X. -N., Weinstein, L. B., Wenaus, T. J., Weyhmiller, S., Wissink, S. W., Wojtsekhowski, B., Wong, C. P., Wood, M. H., Wunderlich, Y., Wyslouch, B., Xiao, B. W., Xie, W., Xiong, W., Xu, N., Xu, Q. H., Xu, Z., Yaari, D., Yao, X., Ye, Z., Ye, Z. H., Yero, C., Yuan, F., Zajc, W. A., Zhang, C., Zhang, J., Zhao, F., Zhao, Y., Zhao, Z. W., Zheng, X., Zhou, J., and Zurek, M.

Subjects
High Energy Physics - Phenomenology, High Energy Physics - Experiment, Nuclear Experiment, Nuclear Theory
Abstract

This White Paper presents the community inputs and scientific conclusions from the Hot and Cold QCD Town Meeting that took place September 23-25, 2022 at MIT, as part of the Nuclear Science Advisory Committee (NSAC) 2023 Long Range Planning process. A total of 424 physicists registered for the meeting. The meeting highlighted progress in Quantum Chromodynamics (QCD) nuclear physics since the 2015 LRP (LRP15) and identified key questions and plausible paths to obtaining answers to those questions, defining priorities for our research over the coming decade. In defining the priority of outstanding physics opportunities for the future, both prospects for the short (~ 5 years) and longer term (5-10 years and beyond) are identified together with the facilities, personnel and other resources needed to maximize the discovery potential and maintain United States leadership in QCD physics worldwide. This White Paper is organized as follows: In the Executive Summary, we detail the Recommendations and Initiatives that were presented and discussed at the Town Meeting, and their supporting rationales. Section 2 highlights major progress and accomplishments of the past seven years. It is followed, in Section 3, by an overview of the physics opportunities for the immediate future, and in relation with the next QCD frontier: the EIC. Section 4 provides an overview of the physics motivations and goals associated with the EIC. Section 5 is devoted to the workforce development and support of diversity, equity and inclusion. This is followed by a dedicated section on computing in Section 6. Section 7 describes the national need for nuclear data science and the relevance to QCD research., Comment: QCD Town Meeting White Paper, as submitted to 2023 NSAC LRP committee on Feb. 28, 2023

Published
2023
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35. Accuracy of a Cancer Registry Versus Clinical Care Team Chart Abstraction in Identifying Cancer Recurrence

Author

Elsa A. Sutton, MD, Benjamin C. Kamdem Talom, BA, Daniel K. Ebner, MD, MPH, Taylor M. Weiskittel, MS, William G. Breen, MD, Roman O. Kowalchuk, MD, Heather J. Gunn, PhD, Courtney N. Day, MS, Eric J. Moore, MD, Sara J. Holton, CTR, BS Health/Health Care Administration/Management, Kathryn M. Van Abel, MD, Chadi N. Abdel-Halim, MD, David M. Routman, MD, and Mark R. Waddle, MD

Subjects
Medicine (General), R5-920
Abstract

Objective: To evaluate the completeness and reliability of recurrence data from an institutional cancer registry for patients with head and neck cancer. Patients and Methods: Recurrence information was collected by radiation oncology and otolaryngology researchers. This was compared with the institutional cancer registry for continuous patients treated with radiation therapy for head and neck cancer at a tertiary cancer center. The sensitivity and specificity of institutional cancer registry data was calculated using manual review as the gold standard. False negative recurrences were compared to true positive recurrences to assess for differences in patient characteristics. Results: A total of 1338 patients who were treated from January 1, 2010, through December 31, 2017, were included in a cancer registry and underwent review. Of them, 375 (30%) had confirmed cancer recurrences, 45 (3%) had concern for recurrence without radiologic or pathologic confirmation, and 31 (2%) had persistent disease. Most confirmed recurrences were distant (37%) or distant plus locoregional (29%), whereas few were local (11%), regional (9%), or locoregional (14%) alone. The cancer registry accuracy was 89.4%, sensitivity 61%, and specificity 99%. Time to recurrence was associated with registry accuracy. True positives had recurrences at a median of 414 days vs 1007 days for false negatives. Conclusion: Currently, institutional cancer registry recurrence data lacks the required accuracy for implementation into studies without manual confirmation. Longer follow-up of cancer status will likely improve sensitivity. No identified differences in patients accounted for differences in sensitivity. New, ideally automated, data abstraction tools are needed to improve detection of cancer recurrences and minimize manual chart review.

Published
2024
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37. Solanum pimpinellifolium exhibits complex genetic resistance to Pseudomonas syringae pv. tomato

Author

Jana A. Hassan, Nathan Diplock, Ilea J. Chau-Ly, Jamie Calma, Elizabeth Boville, Steven Yee, Taylor M. Harris, and Jennifer D. Lewis

Subjects
bacterial speck, genetic diversity, quantitative trait loci (QTL), plant breeding, Pseudomonas syringae, Solanum pimpinellifolium, Plant culture, SB1-1110
Abstract

Pseudomonas syringae pv. tomato (Pst) is the causal agent of bacterial speck disease in tomatoes. The Pto/Prf gene cluster from Solanum pimpinellifolium was introgressed into several modern tomato cultivars and provided protection against Pst race 0 strains for many decades. However, virulent Pst race 1 strains that evade Pto-mediated immunity now predominate in tomato-growing regions worldwide. Here we report the identification of resistance to a Pst race 1 strain (Pst19) in the wild tomato accession S. pimpinellifolium LA1589 (hereafter LA1589), using our rapid high-throughput seedling screen. LA1589 supports less bacterial growth than cultivars, and does not exhibit a hypersensitive response to Pst19. We tested an existing set of 87 Inbred Backcross Lines (IBLs) derived from a cross between susceptible Solanum lycopersicum E-6203 and Solanum pimpinellifolium LA1589 for resistance to Pst19. Using single-marker analysis, we identified three genomic regions associated with resistance. Bacterial growth assays on IBLs confirmed that these regions contribute to resistance in planta. We also mapped candidate genes associated with resistance in a cross between the Solanum lycopersicum var. lycopersicum cultivar Heinz BG-1706 and S. pimpinellifolium LA1589. By comparing candidates from the two mapping approaches, we were able to identify 3 QTL and 5 candidate genes in LA1589 for a role in resistance to Pst19. This work will assist in molecular marker-assisted breeding to protect tomato from bacterial speck disease.

Published
2024
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38. A Sociology of Artificial Intelligence: Inequalities, Power, and Data Justice

Author

Kelly Joyce and Taylor M. Cruz

Subjects
Social Sciences, Sociology (General), HM401-1281
Abstract

Recent years have witnessed a surge of interest in artificial intelligence (AI). To address AI’s growing visibility and importance, the authors edited a special collection that showcases cutting-edge sociological research on AI in areas such as health and medicine, work and labor, new research methodologies, and policy. The articles collectively position AI as a sociotechnical system, recognizing that AI integrates heterogeneous elements that intertwine the social and the technical. Each article brings different aspects of sociotechnical systems to light. The authors highlight three contributions sociologists are poised to make to the study of AI: (1) critical analysis of AI hype, promotion, and adoption; (2) empirical study of AI’s co-constitution with processes of social life; and (3) identification of avenues for structural change in creating equitable AI futures. The authors call for the development of novel research methods to study distributed AI platforms and for future research on inequalities, power, and data justice.

Published
2024
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39. CelltypeR: A flow cytometry pipeline to characterize single cells from brain organoids

Author

Rhalena A. Thomas, Julien Sirois, Shuming Li, Alexandre Gestin, Ghislaine Deyab, Valerio E.C. Piscopo, Paula Lépine, Meghna Mathur, Carol X.-Q. Chen, Vincent Soubannier, Taylor M. Goldsmith, Lama Fawaz, Thomas M. Durcan, and Edward A. Fon

Subjects
Neuroscience, Cell biology, Omics, Science
Abstract

Summary: Motivated by the cellular heterogeneity in complex tissues, particularly in brain and induced pluripotent stem cell (iPSC)-derived brain models, we developed a complete workflow to reproducibly characterize cell types in complex tissues. Our approach combines a flow cytometry (FC) antibody panel with our computational pipeline CelltypeR, enabling dataset aligning, unsupervised clustering optimization, cell type annotating, and statistical comparisons. Applied to human iPSC derived midbrain organoids, it successfully identified the major brain cell types. We performed fluorescence-activated cell sorting of CelltypeR-defined astrocytes, radial glia, and neurons, exploring transcriptional states by single-cell RNA sequencing. Among the sorted neurons, we identified subgroups of dopamine neurons: one reminiscent of substantia nigra cells most vulnerable in Parkinson’s disease. Finally, we used our workflow to track cell types across a time course of organoid differentiation. Overall, our adaptable analysis framework provides a generalizable method for reproducibly identifying cell types across FC datasets in complex tissues.

Published
2024
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40. Quantitative susceptibility and T1ρ mapping of knee articular cartilage at 3T

Author

Allen A. Champagne, Taylor M. Zuleger, Daniel R. Smith, Alexis B. Slutsky-Ganesh, Shayla M. Warren, Mario E. Ramirez, Lexie M. Sengkhammee, Sagar Mandava, Hongjiang Wei, Davide D. Bardana, Joseph D. Lamplot, Gregory D. Myer, and Jed A. Diekfuss

Subjects
Articular cartilage, T1ρ, QSM, Magnetic resonance imaging, Microstructural integrity, Arthritis, Diseases of the musculoskeletal system, RC925-935
Abstract

T1ρ and Quantitative Susceptibility Mapping (QSM) are evolving as substrates for quantifying the progressive nature of knee osteoarthritis. Objective: To evaluate the effects of spin lock time combinations on depth-dependent T1ρ estimation, in adjunct to QSM, and characterize the degree of shared variance in QSM and T1ρ for the quantitative measurement of articular cartilage. Design: Twenty healthy participants (10 ​M/10F, 22.2 ​± ​3.4 years) underwent bilateral knee MRI using T1ρ MAPPS sequences with varying TSLs ([0–120] ms), along with a 3D spoiled gradient echo for QSM. Five total TSL combinations were used for T1ρ computation, and direct depth-based comparison. Depth-wide variance was assessed in comparison to QSM as a basis to assess for depth-specific variation in T1ρ computations across healthy cartilage. Results: Longer T1ρ relaxation times were observed for TSL combinations with higher spin lock times. Depth-specific differences were documented for both QSM and T1ρ, with most change found at ∼60% depth of the cartilage, relative to the surface. Direct squared linear correlation revealed that most T1ρ TSL combinations can explain over 30% of the variability in QSM, suggesting inherent shared sensitivity to cartilage microstructure. Conclusions: T1ρ mapping is subjective to the spin lock time combinations used for computation of relaxation times. When paired with QSM, both similarities and differences in signal sensitivity may be complementary to capture depth-wide changes in articular cartilage.

Published
2024
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41. A MRSA mystery: how PBP4 and cyclic-di-AMP join forces against β-lactam antibiotics

Author

Taylor M. Gardner and Melinda R. Grosser

Subjects
MRSA, β-lactam resistance, cyclic-di-AMP, methicillin-resistant lacking mec (MRLM), PBP4, gdpP, Microbiology, QR1-502
Abstract

ABSTRACT The high-level resistance to next-generation β-lactams frequently found in Staphylococcus aureus isolates lacking mec, which encodes the transpeptidase PBP2a traditionally associated with methicillin-resistant Staphylococcus aureus (MRSA), has remained incompletely understood for decades. A new study by Lai et al. found that the co-occurrence of mutations in pbp4 and gdpP, which respectively cause increased PBP4-mediated cell wall crosslinking and elevated cyclic-di-AMP levels, produces synergistic β-lactam resistance rivaling that of PBP2a-producing MRSA (L.-Y. Lai, N. Satishkumar, S. Cardozo, V. Hemmadi, et al., mBio 15:e02889-23. 2024, https://doi.org/10.1128/mbio.02889-23). The combined mutations are sufficient to explain the high-level β-lactam resistance of some mec-lacking strains, but the mechanism of synergy remains elusive and an avenue for further research. Importantly, the authors establish that co-occurrence of these mutations leads to antibiotic therapy failure in a Caenorhabditis elegans infection model. These results underscore the need to consider this unique and novel β-lactam resistance mechanism during the clinical diagnosis of MRSA, rather than relying on mec as a diagnostic.

Published
2024
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43. Blurring Boundaries: A Longitudinal Teacher-Researcher Collaboration in South Korea

Author

Kennedy, Laura M., Brown, Clarque, Stables, Nathan, Williams, Taylor M., Moua, Isabel, Hult, Francis M., Series Editor, Cavalcanti, Marilda C., Editorial Board Member, Cenoz, Jasone, Editorial Board Member, Creese, Angela, Editorial Board Member, Gogolin, Ingrid, Editorial Board Member, Hélot, Christine, Editorial Board Member, Janks, Hilary, Editorial Board Member, Kramsch, Claire, Editorial Board Member, Leung, Constant, Editorial Board Member, Lin, Angel, Editorial Board Member, Pennycook, Alastair, Editorial Board Member, Curtis, Jessie Hutchison, editor, and Uştuk, Özgehan, editor

Published
2024
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44. Updates in the Use of Immunohistochemical Stains in Breast and Gynecologic Pathology

Author

Jenkins, Taylor M. and Mehr, Chelsea R.

Subjects
Immunohistochemistry, Tumor proteins -- Diagnosis, Progesterone, Estrogen, Epidermal growth factor, Health, World Health Organization
Abstract

* Context.--The use of immunohistochemical stains in breast and gynecologic pathology has become increasingly complex, with various diagnostic, prognostic, and predictive applications. Objective.--To provide an update and review of immunohistochemical stains used in the practice of breast and gynecologic pathology. Established and new entities are reviewed, with descriptions of histomorphology and immunohistochemical staining patterns and discussion of interpretive pitfalls. Data Sources.--Data were obtained from review of the English-language literature and firsthand experience of the authors in breast and gynecologic pathology. Conclusions.--Many entities in breast and gynecologic pathology benefit from evaluation with various immunohistochemical stains. These studies not only aid in the diagnosis and staging of tumors but also can provide prognostic and predictive information. Updated guidelines for recommended ancillary studies such as mismatch repair, p53, and human epidermal growth factor receptor 2 (HER2) studies in endometrium, as well as estrogen and progesterone receptors and HER2 in breast, are discussed. Finally, the use and interpretation of established and novel immunohistochemical stains are discussed in various breast and gynecologic malignancies. doi: 10.5858/arpa.2022-0467-RA, The use of immunohistochemical (IHC) stains in breast and gynecologic pathology is becoming increasingly complex. Changes in the clinical management of the axilla have necessitated an evaluation of IHC markers [...]

Published
2024
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45. Does Neuromuscular Training Reduce the Risk of Lower-Extremity Musculoskeletal Injury in High School Female Athletes With a History of Sport-Related Concussion?

Author

McPherson, April L., Zuleger, Taylor M., Barber Foss, Kim D., Warren, Shayla M., Hogg, Jennifer A., Diekfuss, Jed A., and Myer, Gregory D.

Subjects
*LEG injuries, *SKELETAL muscle injuries, *SPORTS injuries risk factors, *SPORTS injury prevention, *RISK assessment, *EXERCISE physiology, *BIOMECHANICS, *RESEARCH funding, *QUESTIONNAIRES, *DESCRIPTIVE statistics, *LONGITUDINAL method, *CASE-control method, *CONFIDENCE intervals, *DATA analysis software, *NEURODEVELOPMENTAL treatment, *BRAIN concussion
Abstract

Context: There is a well-established increased risk of lower-extremity (LE) musculoskeletal (MSK) injury following a sport-related concussion (SRC). Neuromuscular training programs improve biomechanics associated with LE MSK injury and reduce LE MSK injury incidence, but their relative effectiveness in athletes with history of SRC is unknown. The purpose of this study was to evaluate LE MSK injury incidence in female adolescent athletes with history of SRC following a neuromuscular training intervention. Design: Prospective case-control. Methods: Seventy-seven adolescent female athletes aged 12–18 years who participated in soccer, volleyball, or basketball were recruited from a single institutional sports medicine research and performance center to complete a 6-week neuromuscular training program prior to competitive athletic season. Group (Control, History of SRC) comparisons of athlete exposure and relative LE MSK injury risk and rates during the competitive athletic season were assessed. Results: Ten injuries were recorded by 9 athletes. Female athletes who reported history of SRC had increased injury risk (Risk Ratio 3.9, 95% CI, 1.1–13.8, P =.01) and increased injury rate (rate ratio 4.1, 95% CI, 1.1–15.8, P =.03) compared with female athletes without history of SRC. Conclusions: Female adolescent athletes with history of SRC showed a greater risk of LE MSK injury compared with athletes with no history of SRC. Future work is still needed to understand the underlying mechanisms associated with future LE MSK injury following SRC and interventions that ameliorate elevated injury risk. [ABSTRACT FROM AUTHOR]

Published
2024
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46. Representativeness of samples enrolled in Alzheimer's disease research centers

Author

Rentería, Miguel Arce, Mobley, Taylor M, Evangelista, Nicole D, Medina, Luis D, Deters, Kacie D, Fox‐Fuller, Joshua T, Minto, Lex R, Avila‐Rieger, Justina, and Bettcher, Brianne M

Subjects
Biological Psychology, Biomedical and Clinical Sciences, Neurosciences, Psychology, Acquired Cognitive Impairment, Mental Health, Neurodegenerative, Aging, Alzheimer's Disease, Behavioral and Social Science, Brain Disorders, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Dementia, Good Health and Well Being, Alzheimer's disease centers, generalizability, racial, ethnic disparities, recruitment, racial/ethnic disparities, Genetics, Biological psychology
Abstract

To generalize findings on the mechanisms and prognosis in Alzheimer's disease and related dementias (ADRD), it is critical for ADRD research to be representative of the population. Sociodemographic and health characteristics across ethnoracial groups included in the National Alzheimer's Coordinating Center sample (NACC) were compared to the nationally representative Health and Retirement Study (HRS).Baseline NACC data (n = 36,639) and the weighted 2010 HRS wave (N = 52,071,840) were included. We assessed covariate balance by calculating standardized mean differences across harmonized covariates (i.e., sociodemographic, health).NACC participants were older, more educated, with worse subjective memory and hearing, but endorsed fewer depressive symptoms compared to HRS participants. While all racial and ethnic groups in NACC differed from HRS participants in the same way overall, these differences were further amplified between racial and ethnic groups.NACC participants do not represent the U.S. population in key demographic and health factors, which differed by race and ethnicity.HighlightsWe examined selection factors included in NACC studies compared to a nationally representative sample.Selection factors included demographic and health factors and self-reported memory concerns.Results suggest that NACC participants are not representative of the U.S. population.Importantly, selection factors differed across racial and ethnic groups.Findings are suggestive of selection bias within NACC studies.

Published
2023

47. The Cool Air

Author

Moore, Taylor M

Subjects
Philosophy and Religious Studies, History and Philosophy Of Specific Fields, History and Philosophy of Specific Fields, Science Studies, History and philosophy of specific fields
Published
2023

48. Stable phase retrieval in function spaces

Author

Freeman, D., Oikhberg, T., Pineau, B., and Taylor, M. A.

Subjects
Mathematics - Functional Analysis, 46B42, 43A46, 42C15
Abstract

Let $(\Omega,\Sigma,\mu)$ be a measure space, and $1\leq p\leq \infty$. A subspace $E\subseteq L_p(\mu)$ is said to do stable phase retrieval (SPR) if there exists a constant $C\geq 1$ such that for any $f,g\in E$ we have $$ \inf_{|\lambda|=1} \|f-\lambda g\|\leq C\||f|-|g|\|. $$ In this case, if $|f|$ is known, then $f$ is uniquely determined up to an unavoidable global phase factor $\lambda$; moreover, the phase recovery map is $C$-Lipschitz. Phase retrieval appears in several applied circumstances, ranging from crystallography to quantum mechanics. In this article, we construct various subspaces doing stable phase retrieval, and make connections with $\Lambda(p)$-set theory. Moreover, we set the foundations for an analysis of stable phase retrieval in general function spaces. This, in particular, allows us to show that H\"older stable phase retrieval implies stable phase retrieval, improving the stability bounds in a recent article of M. Christ and the third and fourth authors. We also characterize those compact Hausdorff spaces $K$ such that $C(K)$ contains an infinite dimensional SPR subspace., Comment: 58 pages

Published
2022

49. Free Banach lattices

Author

Oikhberg, T., Taylor, M. A., Tradacete, P., and Troitsky, V. G.

Subjects
Mathematics - Functional Analysis, 46B42, 46A22, 46A40, 46B80, 47B60
Abstract

We investigate the structure of the free $p$-convex Banach lattice $FBL^{(p)}[E]$ over a Banach space $E$. After recalling why such a free lattice exists, and giving a convenient functional representation of it, we focus our study on how properties of an operator $T:E\rightarrow F$ between Banach spaces transfer to the associated lattice homomorphism $\overline{T}:FBL^{(p)}[E]\rightarrow FBL^{(p)}[F]$. Particular consideration is devoted to the case when the operator $T$ is an isomorphic embedding, which leads us to examine extension properties of operators into $\ell_p$, and several classical Banach space properties such as being a G.T. space. A detailed investigation of basic sequences and sublattices of free Banach lattices is provided. In addition, we begin to build a dictionary between Banach space properties of $E$ and Banach lattice properties of $FBL^{(p)}[E]$. In particular, we characterize the existence of lattice copies of $\ell_1$ in $FBL^{(p)}[E]$ and show that $FBL[E]$ has an upper $p$-estimate if and only if $id_{E^*}$ is $(q,1)$-summing ($\frac{1}{p}+\frac{1}{q}=1$). We also highlight the significant differences between $FBL^{(p)}$-spaces depending on whether $p$ is finite or infinite. For example, we show that $FBL^{(\infty)}[E]$ is lattice isometric to $FBL^{(\infty)}[F]$ whenever $E$ and $F$ have monotone finite dimensional decompositions, while, on the other hand, when $p<\infty$ and $E^*$ is smooth, $FBL^{(p)}[E]$ determines $E$ isometrically., Comment: 154 pages

Published
2022

50. Argument for the radiation-dominated behavior of matter fields in the preinflationary era

Author

Ordines, Taylor M. and Carlson, Eric D.

Subjects
General Relativity and Quantum Cosmology
Abstract

We investigate the leading-order behavior of matter fields in the preinflationary era using the semiclassical approximation. Many inflationary models assume without supporting arguments that the Universe was radiation dominated prior to inflation, leading to modifications of cosmological observables, such as the Cosmic Microwave Background power spectrum. In previous work, we demonstrated that conformally coupled scalar fields do have a radiation-like contribution to the stress-energy tensor at sufficiently early times. In this work, we extend these arguments to apply to massless spin-1 fields and massive or massless spin-$\frac{1}{2}$ fields. We find massless spin-1 fields always have a radiation-like contribution. For spin-$\frac{1}{2}$ fields, we find the contribution at early times is radiation-like assuming this is the dominant contribution to the stress-energy tensor.

Published
2022
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