Search

Your search keyword '"Tchetverikov, I"' showing total 122 results
Start Over Author "Tchetverikov, I"
Sorry, I don't understand your search. ×
122 results on '"Tchetverikov, I"'

1. Arthroscopic synovectomy versus intra-articular injection of corticosteroids for the management of refractory psoriatic or rheumatoid arthritis of the wrist: study protocol for a randomized controlled trial (ARCTIC trial)

Author

d’Ailly, P. N., Deugd, C., Schep, N. W. L., Kuijper, T. M., Kok, M. R., Willemze, A., Coert, J. H., de Jong, P. H. P., Lam-Tse, W. K., van der Helm-van Mil, A. H. M., Tchetverikov, I., Weel-Koenders, A. E. A. M., and Bisoendial, R. J.

Published
2023
Full Text
View/download PDF

3. OP0065 THE DETERMINANTS OF RADIOGRAPHIC PROGRESSION IN EARLY PSA PATIENTS

Author

Koc, G. H., primary, Kok, M. R., additional, Luime, J., additional, Tchetverikov, I., additional, Kasiem, F. R., additional, Wervers, K., additional, Goekoop-Ruiterman, Y., additional, Korswagen, L. A., additional, Fodili, F., additional, Van Oosterhout, M., additional, Denissen, N. H. A. M., additional, Dolhain, R., additional, and Vis, M., additional

Published
2023
Full Text
View/download PDF

6. Additional file 2 of Arthroscopic synovectomy versus intra-articular injection of corticosteroids for the management of refractory psoriatic or rheumatoid arthritis of the wrist: study protocol for a randomized controlled trial (ARCTIC trial)

Author

d’Ailly, P. N., Deugd, C., Schep, N. W. L., Kuijper, T. M., Kok, M. R., Willemze, A., Coert, J. H., de Jong, P. H. P., Lam-Tse, W. K., van der Helm-van Mil, A. H. M., Tchetverikov, I., Weel-Koenders, A. E. A. M., and Bisoendial, R. J.

Abstract

Additional file 2. The statistical code to simulate the study power.

Published
2023
Full Text
View/download PDF

7. Additional file 1 of Arthroscopic synovectomy versus intra-articular injection of corticosteroids for the management of refractory psoriatic or rheumatoid arthritis of the wrist: study protocol for a randomized controlled trial (ARCTIC trial)

Author

d’Ailly, P. N., Deugd, C., Schep, N. W. L., Kuijper, T. M., Kok, M. R., Willemze, A., Coert, J. H., de Jong, P. H. P., Lam-Tse, W. K., van der Helm-van Mil, A. H. M., Tchetverikov, I., Weel-Koenders, A. E. A. M., and Bisoendial, R. J.

Abstract

Additional file 1. Description of planned statistical analyses for the PRWE outcome conform the ‘estimands’ framework.

Published
2023
Full Text
View/download PDF

8. Impact of triage by a rheumatologist on appropriateness of referrals from primary to secondary care: a cluster randomized trial.

Author

van Delft, ETAM, Lopes Barreto, D, Han, KH, Tchetverikov, I, Evertse, A, Kuijper, TM, Hazes, JMW, and Weel-Koenders, AEAM

Subjects
CLUSTER randomized controlled trials, SECONDARY care (Medicine), RHEUMATOLOGISTS, PRIMARY care, PATIENT experience, MEDICAL triage
Abstract

The quality of referrals is often criticized, and the effectiveness of improvement efforts remains uncertain. We assessed the impact of a rheumatologist triaging patients in primary care on the appropriateness of referrals to secondary care, healthcare utilization, and patient experience and outcomes. A cluster randomized controlled trial was conducted with patients experiencing musculoskeletal complaints. Intervention practices deployed an experienced rheumatologist triaging patients through in-person review. Usual care was performed in control practices, where practitioners referred patients based on their own judgement. The primary outcome was the proportion of inflammatory rheumatic diseases (IRDs) diagnosed by rheumatologists in referred patients. Healthcare utilization (iMTA Medical Consumption Questionnaire), quality of life (EuroQol 5 Dimensions), and experience of care (Consumer Quality Index) were determined after 3 months of follow-up. Data were analysed according to the intention-to-treat principle. In total, 544 participants were included [mean age 51.4 (range 18–87) years; 24% were men]. Of all referred patients, 51% had an IRD in the intervention group versus 21% in the control group (p = 0.035). After 3 months of follow-up, patients from the triage intervention showed lower healthcare utilization (p = 0.006) and higher quality of life (p = 0.011), without a decline in experienced quality of care (p = 0.712), compared to controls. Triage by a rheumatologist in primary care provides appropriate care and adequate experience of care, leading to a higher quality of life. Long-term evidence is needed to assess the value on cost-effectiveness before implementing this strategy nationwide. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

9. Importance of quick attainment of minimal disease activity for a positive impact on lives of patients with psoriatic arthritis

Author

Henkemans, S.V.J.S., Jong, P.H.P. de, Luime, J.J., Kok, M.R., Tchetverikov, I., Kasiem, F.R., Welby, S., Prickett, A.R., Mil, A.H.M.V., Vis, M., Cicero, and Rheumatology

Subjects
psoriatic arthritis, Treatment Outcome, Rheumatology, patient reported outcome measures, biological therapy, Antirheumatic Agents, Immunology, Arthritis, Psoriatic, Quality of Life, Immunology and Allergy, Humans, Fatigue
Abstract

ObjectiveTo compare patient-reported outcomes (PROs) from the first year to the third year between patients with psoriatic arthritis (PsA) who achieved minimal disease activity (MDA) in the first year after diagnosis and those who did not.MethodsConsecutive, newly diagnosed, patients with DMARD naïve PsA with oligoarthritis or polyarthritis were selected from the Dutch southwest Early PsA cohoRt. Patients were categorised in three groups: (1) Patients who were in MDA at both 9 months and 12 months after diagnosis (sustained MDA); (2) Patients who achieved MDA in the first year but in whom it was not sustained at both 9 months and 12 months (non-sustained MDA); (3) Patients who did not achieve MDA in the first year (no MDA). PROs were compared between groups from the first year to the third year after diagnosis using a linear mixed model.Results240 patients were selected; 104 (43%) were classified as sustained MDA, 60 (25%) as non-sustained MDA and 76 (32%) as no MDA. Patients who did not achieve MDA in the first year experienced remarkably lower PROs during follow-up, compared with the sustained MDA group: health status (European Quality of life 5-Dimensions 5-Levels) was 0.23 units lower (95% CI −0.28 to −0.18), functional impairment (Health Assessment Questionnaire-Disability Index) was 0.81 units higher (95% CI 0.70 to 0.92), pain (Visual Analogue Scale) was 35.38 mm higher (95% CI 30.57 to 40.18), fatigue (Bristol Rheumatoid Arthritis Fatigue-Multidimensional Questionnaire) was 17.88 units higher (95% CI 14.60 to 21.16), and anxiety and depression (Hospital Anxiety and Depression Scale) were, respectively, 3.26 units (95% CI 2.25 to 4.27) and 4.04 units higher (95% CI 3.10 to 4.99).ConclusionFailure to achieve MDA in the first year after PsA diagnosis was associated with worse PROs that persisted over the years.

Published
2022

17. OP0211 PATERNAL INFLAMMATORY ARTHRITIS IS ASSOCIATED WITH A HIGHER RISK OF MISCARRIAGES: RESULTS OF A LARGE MULTICENTER STUDY (IFAME-FERTILITY)

Author

Perez-Garcia, L. F., primary, Röder, E., additional, Goekoop, R., additional, Kok, M. R., additional, Kok, P., additional, Smeele, H. T., additional, Tchetverikov, I., additional, Van der Helm - van Mil, A., additional, Van der Kaap, J. H., additional, Krijthe, B., additional, and Dolhain, R., additional

Published
2021
Full Text
View/download PDF

20. OP0212 MEN DIAGNOSED WITH INFLAMMATORY ARTHRITIS BEFORE THE AGE OF 40 YEARS HAVE A LOWER FERTILITY RATE THAN THOSE DIAGNOSED AFTER THE AGE OF 40 YEARS: RESULTS OF A LARGE MULTICENTER STUDY (IFAME-FERTILITY)

Author

Perez-Garcia, L. F., primary, Röder, E., additional, Goekoop, R., additional, Hazes, J., additional, Kok, M. R., additional, Kok, P., additional, Smeele, H. T., additional, Tchetverikov, I., additional, Van der Kaap, J. H., additional, Van der Helm - van Mil, A., additional, Krijthe, B., additional, and Dolhain, R., additional

Published
2021
Full Text
View/download PDF

21. Lessons learned from clinical phenotypes in early psoriatic arthritis: the real-world Dutch south west Early Psoriatic ARthritis study

Author

Kasiem, FR, primary, Luime, JJ, additional, Vis, M, additional, Kok, MR, additional, Wervers, K, additional, Gerards, AH, additional, Appels, CWY, additional, van der Graaff, WL, additional, Starmans-Kool, MJF, additional, Goekoop-Ruiterman, YPM, additional, van Groenendael, JHLM, additional, Korswagen, L-A, additional, Veris-van Dieren, JJ, additional, Hazes, JMW, additional, and Tchetverikov, I, additional

Published
2020
Full Text
View/download PDF

23. OP0057 SEX SPECIFIC DIFFERENCES IN EARLY PSORIATIC ARTHRITIS

Author

Passia, E., primary, Vis, M., additional, Coates, L. C., additional, Soni, A., additional, Tchetverikov, I., additional, Gerards, A., additional, Korswagen, L. A., additional, Kok, M. R., additional, Van der Graaff, W., additional, Veris-van Dieren, J., additional, Denissen, N., additional, Fodili, F., additional, Starmans, M., additional, Goekoop-Ruiterman, Y., additional, Van Oosterhout, M., additional, and Luime, J., additional

Published
2020
Full Text
View/download PDF

30. Lessons learned from clinical phenotypes in early psoriatic arthritis: the real-world Dutch south west Early Psoriatic ARthritis study.

Author

Kasiem, FR, Luime, JJ, Vis, M, Kok, MR, Wervers, K, Gerards, AH, Appels, CWY, van der Graaff, WL, Starmans-Kool, MJF, Goekoop-Ruiterman, YPM, van Groenendael, JHLM, Korswagen, L-A, Veris-van Dieren, JJ, Hazes, JMW, Tchetverikov, I, Kasiem, F R, Luime, J J, Kok, M R, Gerards, A H, and van der Graaff, W L

Subjects
PSORIATIC arthritis, SICK leave, DECISION support systems, QUALITY of work life, PHENOTYPES, HOSPITAL patients
Abstract

Objective: This paper describes the baseline demographics, clinical characteristics, and patient-reported outcomes (PROs) according to clinical phenotype of patients with early psoriatic arthritis (PsA) for the purpose of creating a decision support system for daily clinical practice.Method: Patients with newly diagnosed PsA were included in the Dutch south west Early Psoriatic ARthritis (DEPAR) study. No classification criteria were applied, to ensure collection of real-world data on demographics, medication, clinical characteristics, and PROs. An IT infrastructure facilitated data collection.Results: We described 527 patients, categorized according to the clinical phenotype stated by the rheumatologist at the time of diagnosis, namely monoarthritis (15%), oligoarthritis (40%), polyarthritis (23%), enthesitis (10%), axial disease (2%), and dactylitis (10%). Overall psoriasis severity was mild and 83 patients (16%) had no psoriasis. Short-term sick leave (> 1 day per 4 weeks) was 17% and long-term sick leave (> 4 weeks) was 4%. The group with phenotype enthesitis reported the longest duration of complaints, had the highest fatigue scores, and contained the highest percentage of patients with a Hospital Anxiety and Depression Scale (HADS) anxiety score ≥ 8 and depression score ≥ 8.Conclusion: PsA patients presenting at outpatient clinics in the Netherlands had a mild degree of psoriasis, with impairment of quality of life and work productivity. Most patients presented with phenotype oligoarthritis. Those presenting with phenotype enthesitis more often reported scores suggestive of an anxiety or depression disorder and fatigue. It is important for attending rheumatologists to be aware of these differences when assessing patients with PsA. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

31. Leflunomide and methotrexate reduce levels of activated matrix metalloproteinases in complexes with (alpha sub 2) macroglobulin in serum of rheumatoid arthritis patients

Author

Tchetverikov, I., Kraan, M.C., van El, B., Hanemaaijer, R., DeGroot, J., and Huizinga, T.W.J.

Subjects
Leflunomide -- Dosage and administration, Leflunomide -- Physiological aspects, Methotrexate -- Dosage and administration, Methotrexate -- Physiological aspects, Metalloproteins -- Physiological aspects, Rheumatoid arthritis -- Development and progression, Rheumatoid arthritis -- Physiological aspects, Rheumatoid arthritis -- Research, Health
Published
2008

39. AB0722 The impact of a referral strategy for axial spondyloarthritis in young patients with chronic low back pain: short term outcomes of the impact study

Author

Hoeven, L Van, primary, Korver, A, additional, Appels, C, additional, Hazes, J, additional, Hoogen, F van den, additional, Oosterhout, M van, additional, Oostveen, J, additional, Spoorenberg, J, additional, Tchetverikov, I, additional, Kuijper, T, additional, Koes, B, additional, and Weel, A, additional

Published
2017
Full Text
View/download PDF

42. Effects of psychosocial factors on monitoring treatment effect in newly diagnosed rheumatoid arthritis patients over time: response data from the tREACH study.

Author

Kuijper, TM, Luime, JJ, Xiong, H, de Jong, PHP, van der Lubbe, PAHM, van Zeben, D, Tchetverikov, I, Hazes, JMW, and Weel, AEAM

Subjects
RHEUMATOID arthritis, AUTOIMMUNE diseases, RHEUMATISM, BLOOD hyperviscosity syndrome, PSYCHOSOCIAL factors, THERAPEUTIC use of glucocorticoids, METHOTREXATE, ANTIRHEUMATIC agents, SULFONAMIDES, ANXIETY, COMBINATION drug therapy, COMPARATIVE studies, MENTAL depression, LONGITUDINAL method, RESEARCH methodology, MEDICAL cooperation, PATIENT monitoring, RESEARCH, TIME, EVALUATION research, RANDOMIZED controlled trials, TREATMENT effectiveness, DISEASE progression, DISEASE complications, PSYCHOLOGY, THERAPEUTICS
Abstract

Objectives: To investigate whether, apart from effects of patient- and disease-related factors, psychosocial factors have additional effects on disease activity; and which factors are most influential during the first year of treatment in early rheumatoid arthritis (RA).Method: The study assessed 15 month follow-up data from patients in tREACH, a randomized clinical trial comparing initial triple disease-modifying anti-rheumatic drug therapy to methotrexate monotherapy, with glucocorticoid bridging in both groups. Patients were evaluated every 3 months and treated to target. Associations between Disease Activity Score (DAS) at 3, 9, and 15 months and psychosocial factors (anxiety, depression, fatigue, and coping with pain) at the previous visit were assessed by multivariable linear regression correcting for demographic, clinical, and treatment-related factors.Results: At 3, 9, and 15 months of follow-up, 265, 251, and 162 patients, respectively, were available for analysis. Baseline anxiety and coping with pain were associated with DAS at 3 months; coping with pain at 6 months was associated with DAS at 9 months, and fatigue at 12 months with DAS at 15 months. Psychosocial factors were moderately correlated. Effects on DAS were mainly due to tender joint count and global health.Conclusion: Psychosocial factors have additional effects on DAS throughout the first year of treatment in early RA. A change was observed from anxiety and coping with pain at baseline being associated with subsequent DAS towards fatigue being associated with subsequent DAS at 12 months. Owing to the explorative nature of this study, more research is needed to confirm this pattern. [ABSTRACT FROM AUTHOR]

Published
2018
Full Text
View/download PDF

50. Leflunomide and methotrexate reduce levels of activated matrix metalloproteinases in complexes with α2 macroglobulin in serum of rheumatoid arthritis patients

Author

Tchetverikov, I., Kraan, M.C., El, B. van, Hanemaaijer, R., Groot, J. de, and Huizinga, T.W.J.

Subjects
drug dose increase, rheumatoid arthritis, Male, Biomedical Research, matrix metalloproteinase, drug exposure, loading drug dose, analysis, Phenylalanine, Down-Regulation, Thiophenes, methotrexate, Statistics, Nonparametric, Arthritis, Rheumatoid, drug activity, complex formation, teriflunomide, tissue inhibitor of metalloproteinase 1, Humans, controlled study, alpha-Macroglobulins, Enzyme Inhibitors, Biology, Aged, alpha 2 macroglobulin, leflunomide, systemic circulation, C reactive protein, quantitative analysis, drug effect, Isoxazoles, clinical study, Middle Aged, major clinical study, Matrix Metalloproteinases, drug efficacy, C-Reactive Protein, priority journal, protein blood level, Antirheumatic Agents, Multiprotein Complexes, blood sampling, Biological Markers, Female, disease activity, serum
Abstract

Objective: To analyse the effects of leflunomide and methotrexate treatment on matrix metalloproteinase (MMP) activity levels in a2 macroglobulin/MMP (α2M/MMP) complexes in the systemic circulation of rheumatoid arthritis (RA) patients. Methods: A total of 102 RA patients from a prospective, double-blind, randomised clinical trial comparing leflunomide and methotrexate were selected; clinical data and blood samples were collected at baseline, at 4 months and at 1 year. Serum MMP activity levels in α2M were quantified using low molecular weight fluorogenic substrates, indicating the proportion of activated MMPs that were not inhibited by specific tissue inhibitors of MMP (TIMP). Results: Patients had active disease as shown by high disease activity score (DAS, mean of 6.9 and 7.0 for methotrexate and leflunomide patients respectively), which was reduced over the study period (4.2 and 5.2 respectively, p

Published
2008

Catalog

Books, media, physical & digital resources
See catalog results