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687 results on '"Tegenthoff M"'

1. Age-related changes in the joint position sense of the human hand

Author

Kalisch T, Kattenstroth JC, Kowalewski R, Tegenthoff M, and Dinse HR

Subjects
Aging, Hand functions, Proprioception, Geriatrics, RC952-954.6
Abstract

Tobias Kalisch,1,2,* Jan-Christoph Kattenstroth,2,* Rebecca Kowalewski,2 Martin Tegenthoff,1 Hubert R Dinse21Department of Neurology, BG-Kliniken Bergmannsheil, Ruhr-University Bochum, Bochum, Germany; 2Neural Plasticity Lab, Institute for Neuroinformatics, Ruhr-University Bochum, Bochum, Germany*These authors contributed equally to this workAbstract: Age-related changes in lower limb joint position sense and their contributions to postural stability are well documented. In contrast, only a few studies have investigated the effect of age on proprioceptive hand function. Here, we introduce a novel test for measuring joint position sense in the fingers of the human hand. In a concurrent matching task, subjects had to detect volume differences between polystyrene balls grasped with their dominant (seven test stimuli: 126–505 cm3) and their nondominant hand (three reference stimuli: 210, 294, and 505 cm3). A total of 21 comparisons were performed to assess the number of errors, the weight of errors (ie, the volume difference between test and reference stimuli), and the direction of errors (ie, over- or underestimation of test stimulus). The test was applied to 45 healthy subjects aged 21 to 79 years. Our results revealed that all variables changed significantly with age, with the number of errors showing the strongest increase. We also assessed tactile acuity (two-point discrimination thresholds) and sensorimotor performance (pegboard performance) in a subset of subjects, but these scores did not correlate with joint position sense performance, indicating that the test reveals specific information about joint position sense that is not captured with pure sensory or motor tests. The average test–retest reliability assessed on 3 consecutive days was 0.8 (Cronbach's alpha). Our results demonstrate that this novel test reveals age-related decline in joint position sense acuity that is independent from sensorimotor performance.Keywords: aging, hand functions, joint position sense

Published
2012

20. Abstracts

Author

Weissofner, A., Micallef, J., Baerlocher, K., Karl, H., Haffner, B., Trawöger, R., Maurer, H., Ausserer, B., Krassnitzer, S., Könner, Ch., Covi, P., Rücker, J., Schneider, W., Harder, S., Zielen, S., Zin-U, B., Bock, U., Lauffer, H., Rey, M., Scharf, J., Wenzel, D., Wölfel, D., Wagner, J., Exner, H., Hagmüller, G., Weinstabl, C., Richling, B., Plainer, B., Aloy, A., Czech, T., Spiss, C. K., Mast, M., Erbs, G., Stöllberger, C., Bachl, J. Ch., Peschl, L., Slany, J., Brainin, M., Heß, M., Nowak, G., Schwohl, Th., Diederich, K.-W., Sheikhzadeh, A., Seit, E., Loeb, M., Eich, F. X., Leititis, J. U., Kronenberg, H., Ulrich, M., Lang, M., Kraft, A., Rohling, R., Link, J., Kretz, F. J., Siebenlist, D., Gattenlöhner, W., Loimer, N., Lenz, K., Presslich, O., Schmid, R., Lechner, P., Anderhuber, F., Thies, P., Janisch, H. D., v. Kleist, D. H., Hoeft, S., Hampel, K. E., Donner, A., Seidler, D., Fitzgerald, R., Lackner, F., Graninger, W., Schwarz, S., Hlozanek, Ch., Jaspert, A., Kotterba, S., Tegenthoff, M., Malin, J.-P., Schmidt, A., Binner, L., Hombach, V., König, P., Künz, A., Harf, Ch., van Vyve, Th., Welter, R., Simbruner, G., Kirchner, L., Glatzl-Hawlik, M., Weninger, M., Paltinger, N., Wieland, W., Mertes, N., Sciuk, J., Wendt, M., Bock, T. A., Heintz, B., Sieberth, H. G., Peters, P., Saborowski, F., Genuß, G.-R., Brusis, T., Feldges, A., Kalff, R., Rosenthal, E., Grote, W., Lenz, Kurt, editor, Laggner, Anton N., editor, Deutsch, Erwin, editor, Binder, Heinrich, editor, Gadner, Helmut, editor, Grimm, Georg, editor, Kleinberger, Gunther, editor, Ritz, Rudolf, editor, Schuster, Hans Peter, editor, and Zaunschirm, Harald Andrew, editor

Published
1990
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23. Frequency drift in MR spectroscopy at 3T

Author

Hui, SCN, Mikkelsen, M, Zollner, HJ, Ahluwalia, V, Alcauter, S, Baltusis, L, Barany, DA, Barlow, LR, Becker, R, Berman, J, Berrington, A, Bhattacharyya, PK, Blicher, JU, Bogner, W, Brown, MS, Calhoun, VD, Castillo, R, Cecil, KM, Choi, YB, Chu, WCW, Clarke, WT, Craven, AR, Cuypers, K, Dacko, M, de la Fuente-Sandoval, C, Desmond, P, Domagalik, A, Dumont, J, Duncan, NW, Dydak, U, Dyke, K, Edmondson, DA, Ende, G, Ersland, L, Evans, CJ, Fermin, ASR, Ferretti, A, Fillmer, A, Gong, T, Greenhouse, I, Grist, JT, Gu, M, Harris, AD, Hatz, K, Heba, S, Heckova, E, Hegarty, JP, Heise, K-F, Honda, S, Jacobson, A, Jansen, JFA, Jenkins, CW, Johnston, SJ, Juchem, C, Kangarlu, A, Kerr, AB, Landheer, K, Lange, T, Lee, P, Levendovszky, SR, Limperopoulos, C, Liu, F, Lloyd, W, Lythgoe, DJ, Machizawa, MG, MacMillan, EL, Maddock, RJ, Manzhurtsev, A, Martinez-Gudino, ML, Miller, JJ, Mirzakhanian, H, Moreno-Ortega, M, Mullins, PG, Nakajima, S, Near, J, Noeske, R, Nordhoy, W, Oeltzschner, G, Osorio-Duran, R, Otaduy, MCG, Pasaye, EH, Peeters, R, Peltier, SJ, Pilatus, U, Polomac, N, Porges, EC, Pradhan, S, Prisciandaro, JJ, Puts, NA, Rae, CD, Reyes-Madrigal, F, Roberts, TPL, Robertson, CE, Rosenberg, JT, Rotaru, D-G, Tuura, RLO, Saleh, MG, Sandberg, K, Sangill, R, Schembri, K, Schrantee, A, Semenova, NA, Singel, D, Sitnikov, R, Smith, J, Song, Y, Stark, C, Stoffers, D, Swinnen, SP, Tain, R, Tanase, C, Tapper, S, Tegenthoff, M, Thiel, T, Thioux, M, Truong, P, van Dijk, P, Vella, N, Vidyasagar, R, Vovk, A, Wang, G, Westlye, LT, Wilbur, TK, Willoughby, WR, Wilson, M, Wittsack, H-J, Woods, AJ, Wu, Y-C, Xu, J, Lopez, MY, Yeung, DKW, Zhao, Q, Zhou, X, Zupan, G, Edden, RAE, Hui, SCN, Mikkelsen, M, Zollner, HJ, Ahluwalia, V, Alcauter, S, Baltusis, L, Barany, DA, Barlow, LR, Becker, R, Berman, J, Berrington, A, Bhattacharyya, PK, Blicher, JU, Bogner, W, Brown, MS, Calhoun, VD, Castillo, R, Cecil, KM, Choi, YB, Chu, WCW, Clarke, WT, Craven, AR, Cuypers, K, Dacko, M, de la Fuente-Sandoval, C, Desmond, P, Domagalik, A, Dumont, J, Duncan, NW, Dydak, U, Dyke, K, Edmondson, DA, Ende, G, Ersland, L, Evans, CJ, Fermin, ASR, Ferretti, A, Fillmer, A, Gong, T, Greenhouse, I, Grist, JT, Gu, M, Harris, AD, Hatz, K, Heba, S, Heckova, E, Hegarty, JP, Heise, K-F, Honda, S, Jacobson, A, Jansen, JFA, Jenkins, CW, Johnston, SJ, Juchem, C, Kangarlu, A, Kerr, AB, Landheer, K, Lange, T, Lee, P, Levendovszky, SR, Limperopoulos, C, Liu, F, Lloyd, W, Lythgoe, DJ, Machizawa, MG, MacMillan, EL, Maddock, RJ, Manzhurtsev, A, Martinez-Gudino, ML, Miller, JJ, Mirzakhanian, H, Moreno-Ortega, M, Mullins, PG, Nakajima, S, Near, J, Noeske, R, Nordhoy, W, Oeltzschner, G, Osorio-Duran, R, Otaduy, MCG, Pasaye, EH, Peeters, R, Peltier, SJ, Pilatus, U, Polomac, N, Porges, EC, Pradhan, S, Prisciandaro, JJ, Puts, NA, Rae, CD, Reyes-Madrigal, F, Roberts, TPL, Robertson, CE, Rosenberg, JT, Rotaru, D-G, Tuura, RLO, Saleh, MG, Sandberg, K, Sangill, R, Schembri, K, Schrantee, A, Semenova, NA, Singel, D, Sitnikov, R, Smith, J, Song, Y, Stark, C, Stoffers, D, Swinnen, SP, Tain, R, Tanase, C, Tapper, S, Tegenthoff, M, Thiel, T, Thioux, M, Truong, P, van Dijk, P, Vella, N, Vidyasagar, R, Vovk, A, Wang, G, Westlye, LT, Wilbur, TK, Willoughby, WR, Wilson, M, Wittsack, H-J, Woods, AJ, Wu, Y-C, Xu, J, Lopez, MY, Yeung, DKW, Zhao, Q, Zhou, X, Zupan, G, and Edden, RAE

Abstract

PURPOSE: Heating of gradient coils and passive shim components is a common cause of instability in the B0 field, especially when gradient intensive sequences are used. The aim of the study was to set a benchmark for typical drift encountered during MR spectroscopy (MRS) to assess the need for real-time field-frequency locking on MRI scanners by comparing field drift data from a large number of sites. METHOD: A standardized protocol was developed for 80 participating sites using 99 3T MR scanners from 3 major vendors. Phantom water signals were acquired before and after an EPI sequence. The protocol consisted of: minimal preparatory imaging; a short pre-fMRI PRESS; a ten-minute fMRI acquisition; and a long post-fMRI PRESS acquisition. Both pre- and post-fMRI PRESS were non-water suppressed. Real-time frequency stabilization/adjustment was switched off when appropriate. Sixty scanners repeated the protocol for a second dataset. In addition, a three-hour post-fMRI MRS acquisition was performed at one site to observe change of gradient temperature and drift rate. Spectral analysis was performed using MATLAB. Frequency drift in pre-fMRI PRESS data were compared with the first 5:20 minutes and the full 30:00 minutes of data after fMRI. Median (interquartile range) drifts were measured and showed in violin plot. Paired t-tests were performed to compare frequency drift pre- and post-fMRI. A simulated in vivo spectrum was generated using FID-A to visualize the effect of the observed frequency drifts. The simulated spectrum was convolved with the frequency trace for the most extreme cases. Impacts of frequency drifts on NAA and GABA were also simulated as a function of linear drift. Data from the repeated protocol were compared with the corresponding first dataset using Pearson's and intraclass correlation coefficients (ICC). RESULTS: Of the data collected from 99 scanners, 4 were excluded due to various reasons. Thus, data from 95 scanners were ultimately analyzed. For the f

Published
2021

38. Event-related functional MRI of awake behaving pigeons at 7T

Author

Behroozi, M., Helluy, X., Ströckens, F., Gao, M., Pusch, R., Tabrik, S., Tegenthoff, M., Otto, T., Axmacher, N., Kumsta, Robert, Moser, D., Genc, E., Güntürkün, O., Behroozi, M., Helluy, X., Ströckens, F., Gao, M., Pusch, R., Tabrik, S., Tegenthoff, M., Otto, T., Axmacher, N., Kumsta, Robert, Moser, D., Genc, E., and Güntürkün, O.

Published
2020

39. Diffusion tensor imaging reveals changes in non-fat infiltrated muscles in Late Onset Pompe Disease

Author

Highfield Research Group, Regenerative Medicine and Stem Cells, Cancer, Brain, Circulatory Health, Rehmann, R, Froeling, M, Rohm, M, Forsting, J, Kley, R A, Schmidt-Wilcke, T, Karabul, N, Meyer-Frießem, C H, Vollert, J, Tegenthoff, M, Vorgerd, M, Schlaffke, L, Highfield Research Group, Regenerative Medicine and Stem Cells, Cancer, Brain, Circulatory Health, Rehmann, R, Froeling, M, Rohm, M, Forsting, J, Kley, R A, Schmidt-Wilcke, T, Karabul, N, Meyer-Frießem, C H, Vollert, J, Tegenthoff, M, Vorgerd, M, and Schlaffke, L

Published
2020

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