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Your search keyword '"Terashima, Yoshiaki"' showing total 167 results
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167 results on '"Terashima, Yoshiaki"'

13. Roles of Cx43-associated protein kinases in suppression of gap junction-mediated chemical coupling by ischemic preconditioning

Author

Naitoh, Kazuyuki, Yano, Toshiyuki, Miura, Tetsuji, Itoh, Takahito, Miki, Takayuki, Tanno, Masaya, Sato, Takahiro, Hotta, Hiroyuki, Terashima, Yoshiaki, and Shimamoto, Kazuaki

Subjects
Membrane proteins -- Properties, Protein kinases -- Properties, Cell junctions -- Properties, Ischemia -- Development and progression, Biological sciences
Abstract

Ischemic preconditioning (PC) suppresses chemical coupling of cardiomyocytes via gap junctions (GJs) during ischemia, which is an adjunct mechanism of protection. The aim of this study was to characterize roles of protein kinases in PC-induced GJ modulation. In isolated rat hearts, ventricular tissues were sampled before and after ischemia with or without PC, and intercalated disc-rich fractions were separated for immunoprecipitation and immunoblotting. Levels of protein kinase C (PKC)-[epsilon], p38mitogen-activated protein kinase (MAPK)-[alpha], and Src coimmunoprecipitated with connexin-43 (Cx43) were increased after ischemia, whereas p38MAPK[beta] was not detected in the Cx43 immunoprecipitates. PC did not modify the level of Cx43-Src complex after ischemia. However, PC enhanced Cx43-PKC[epsilon] complex formation, which was abolished by PKC[epsilon] translocation inhibitory peptide (TIP). In contrast, PC reduced Cx43-p38MAPK[alpha] complex level and p38MAPK activity in the Cx43 immunoprecipitates after ischemia. The effect of PC on Cx43-p38MAPK[alpha] interaction was mimicked by SB-203580, a p38MAPK inhibitor. PC reduced permeability of GJs to Lucifer yellow in the myocardium at 25 min after ischemia, and this effect was abolished by PKC[epsilon]-TIP. SB-203580 increased the GJ permeability at 15 min after ischemia compared with that in untreated controls, but the difference became insignificant 25 min after ischemia. In conclusion, PC has distinct effects on interaction of GJ Cx43 with PKC[epsilon], p38MAPK[alpha], and Src during ischemia. Suppression of GJ permeability during ischemia by PC is primarily achieved by enhanced interaction of Cx43 with PKC[epsilon], which overwhelms the counterbalancing effect of reduced Cx43-p38MAPK[alpha] interaction. connexin-43; protein kinase C; p38 mitogen-activated protein kinase; Src

Published
2009

15. HTS hairpin microstrip filter on r-cut sapphire substrate

Author

Aiga, Fumihiko, Fuke, Hiroyuki, Terashima, Yoshiaki, Yamazaki, Mitsuki, Kayano, Hiroyuki, and Hashimoto, Tatsunori

Subjects
Mobile communication systems -- Research, Wireless communication systems -- Research, Superconductors -- Research, Superconductive devices -- Research, Resonators -- Research, Microwave filters -- Research, Microwave filters -- 2002 AD, Mobile communication systems -- 2002 AD, Resonators -- 2002 AD, Superconductive devices -- 2002 AD, Superconductors -- 2002 AD, Wireless communication systems -- 2002 AD, Wireless technology, Business, Electronics, Electronics and electrical industries
Abstract

A 17-pole high temperature superconductor (HTS) thin-film hairpin microstrip filter on an r-cut sapphire substrate is described.

Published
2003

32. Short Communication: Angiotensin II Type 1 Receptor–Mediated Upregulation of Calcineurin Activity Underlies Impairment of Cardioprotective Signaling in Diabetic Hearts

Author

Hotta, Hiroyuki, primary, Miura, Tetsuji, additional, Miki, Takayuki, additional, Togashi, Nobuhiko, additional, Maeda, Takuto, additional, Kim, Seok Jai, additional, Tanno, Masaya, additional, Yano, Toshiyuki, additional, Kuno, Atsushi, additional, Itoh, Takahito, additional, Satoh, Takahiro, additional, Terashima, Yoshiaki, additional, Ishikawa, Satoko, additional, and Shimamoto, Kazuaki, additional

Published
2010
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46. State-Based Pipelining for Reprogramming Wireless Sensor Networks.

Author

Carbonell, Jaime G., Siekmann, Jörg, Apolloni, Bruno, Howlett, Robert J., Jain, Lakhmi, Miyamaru, Takuya, Mineno, Hiroshi, Terashima, Yoshiaki, Tokunaga, Yuichi, and Mizuno, Tadanori

Abstract

Reprogramming is an important service for wireless sensor network to faciliate management and maintenance tasks. It uses the pipelining method, in which code images are divided into several segments, and segments are distributed in parallel. It is an effective way to reduce completion time. As we increase the number of segment divisions, we can increase the speed of code distribution. However, control messages increase as the number of divided segments increase, and that consumes more energy. The relationship between the speed of distribution and the number of control messages is therefore a trade-off. In existing pipelining, the number of segment divisions is determined as an entire network, that but this determination disregards the status of each node. It impairs the nodes which want to reduce the number of messages for various reasons. To solve this problem, we propose the state-based pipelining that can take the state of each node into consideration. In this method, each node can determine the number of segment divisions by itself. [ABSTRACT FROM AUTHOR]

Published
2007
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