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1. A New Multicomponent Protocol for the Synthesis of Pyridines and Fused Pyridines via a Formal aza [3+3] cycloaddition

Author

Tenti, Giammarco, Teresa Ramos, Ma, and Carlos Menendez, Jose

Abstract

An efficient method for the synthesis of pyridines related to nicotinic acid and their fused derivatives is described. The overall process involves a sequence comprising a four-component reaction that creates the heterocyclic framework from very simple open-chain precursors and two elimination steps, that are performed without the need for purifying any intermediate.

Published
2013

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