11 results on '"Tessema, Melkamu B."'
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2. Global, regional, and national incidence and mortality burden of non-COVID-19 lower respiratory infections and aetiologies, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021
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Bender, Rose Grace, Sirota, Sarah Brooke, Swetschinski, Lucien R, Dominguez, Regina-Mae Villanueva, Novotney, Amanda, Wool, Eve E, Ikuta, Kevin S, Vongpradith, Avina, Rogowski, Emma Lynn Best, Doxey, Matthew, Troeger, Christopher E, Albertson, Samuel B, Ma, Jianing, He, Jiawei, Maass, Kelsey Lynn, A.F.Simões, Eric, Abdoun, Meriem, Abdul Aziz, Jeza Muhamad, Abdulah, Deldar Morad, Abu Rumeileh, Samir, Abualruz, Hasan, Aburuz, Salahdein, Adepoju, Abiola Victor, Adha, Rishan, Adikusuma, Wirawan, Adra, Saryia, Afraz, Ali, Aghamiri, Shahin, Agodi, Antonella, Ahmadzade, Amir Mahmoud, Ahmed, Haroon, Ahmed, Ayman, Akinosoglou, Karolina, AL-Ahdal, Tareq Mohammed Ali, Al-amer, Rasmieh Mustafa, Albashtawy, Mohammed, AlBataineh, Mohammad T., Alemi, Hediyeh, Al-Gheethi, Adel Ali Saeed, Ali, Abid, Ali, Syed Shujait Shujait, Alqahtani, Jaber S, AlQudah, Mohammad, Al-Tawfiq, Jaffar A., Al-Worafi, Yaser Mohammed, Alzoubi, Karem H, Amani, Reza, Amegbor, Prince M, Ameyaw, Edward Kwabena, Amuasi, John H, Anil, Abhishek, Anyanwu, Philip Emeka, Arafat, Mosab, Areda, Damelash, Arefnezhad, Reza, Atalell, Kendalem Asmare, Ayele, Firayad, Azzam, Ahmed Y, Babamohamadi, Hassan, Babin, François-Xavier, Bahurupi, Yogesh, Baker, Stephen, Banik, Biswajit, Barchitta, Martina, Barqawi, Hiba Jawdat, Basharat, Zarrin, Baskaran, Pritish, Batra, Kavita, Batra, Ravi, Bayileyegn, Nebiyou Simegnew, Beloukas, Apostolos, Berkley, James A, Beyene, Kebede A, Bhargava, Ashish, Bhattacharjee, Priyadarshini, Bielicki, Julia A, Bilalaga, Mariah Malak, Bitra, Veera R, Brown, Colin Stewart, Burkart, Katrin, Bustanji, Yasser, Carr, Sinclair, Chahine, Yaacoub, Chattu, Vijay Kumar, Chichagi, Fatemeh, Chopra, Hitesh, Chukwu, Isaac Sunday, Chung, Eunice, Dadana, Sriharsha, Dai, Xiaochen, Dandona, Lalit, Dandona, Rakhi, Darban, Isaac, Dash, Nihar Ranjan, Dashti, Mohsen, Dashtkoohi, Mohadese, Dekker, Denise Myriam, Delgado-Enciso, Ivan, Devanbu, Vinoth Gnana Chellaiyan, Dhama, Kuldeep, Diao, Nancy, Do, Thao Huynh Phuong, Dokova, Klara Georgieva, Dolecek, Christiane, Dziedzic, Arkadiusz Marian, Eckmanns, Tim, Ed-Dra, Abdelaziz, Efendi, Ferry, Eftekharimehrabad, Aziz, Eyre, David William, Fahim, Ayesha, Feizkhah, Alireza, Felton, Timothy William, Ferreira, Nuno, Flor, Luisa S, Gaihre, Santosh, Gebregergis, Miglas W, Gebrehiwot, Mesfin, Geffers, Christine, Gerema, Urge, Ghaffari, Kazem, Goldust, Mohamad, Goleij, Pouya, Guan, Shi-Yang, Gudeta, Mesay Dechasa, Guo, Cui, Gupta, Veer Bala, Gupta, Ishita, Habibzadeh, Farrokh, Hadi, Najah R, Haeuser, Emily, Hailu, Wase Benti, Hajibeygi, Ramtin, Haj-Mirzaian, Arvin, Haller, Sebastian, Hamiduzzaman, Mohammad, Hanifi, Nasrin, Hansel, Jan, Hasnain, Md Saquib, Haubold, Johannes, Hoan, Nguyen Quoc, Huynh, Hong-Han, Iregbu, Kenneth Chukwuemeka, Islam, Md. Rabiul, Jafarzadeh, Abdollah, Jairoun, Ammar Abdulrahman, Jalili, Mahsa, Jomehzadeh, Nabi, Joshua, Charity Ehimwenma, Kabir, Md. Awal, Kamal, Zul, Kanmodi, Kehinde Kazeem, Kantar, Rami S., Karimi Behnagh, Arman, Kaur, Navjot, Kaur, Harkiran, Khamesipour, Faham, Khan, M Nuruzzaman, Khan suheb, Mahammed Ziauddin, Khanal, Vishnu, Khatab, Khaled, Khatib, Mahalaqua Nazli, Kim, Grace, Kim, Kwanghyun, Kitila, Aiggan Tamene Tamene, Komaki, Somayeh, Krishan, Kewal, Krumkamp, Ralf, Kuddus, Md Abdul, Kurniasari, Maria Dyah, Lahariya, Chandrakant, Latifinaibin, Kaveh, Le, Nhi Huu Hanh, Le, Thao Thi Thu, Le, Trang Diep Thanh, Lee, Seung Won, LEPAPE, Alain, Lerango, Temesgen L., Li, Ming-Chieh, Mahboobipour, Amir Ali, Malhotra, Kashish, Mallhi, Tauqeer Hussain, Manoharan, Anand, Martinez-Guerra, Bernardo Alfonso, Mathioudakis, Alexander G., Mattiello, Rita, May, Jürgen, McManigal, Barney, McPhail, Steven M, Mekene Meto, Tesfahun, Mendez-Lopez, Max Alberto Mendez, Meo, Sultan Ayoub, Merati, Mohsen, Mestrovic, Tomislav, Mhlanga, Laurette, Minh, Le Huu Nhat, Misganaw, Awoke, Mishra, Vinaytosh, Misra, Arup Kumar, Mohamed, Nouh Saad, Mohammadi, Esmaeil, Mohammed, Mesud, Mohammed, Mustapha, Mokdad, Ali H, Monasta, Lorenzo, Moore, Catrin E, Motappa, Rohith, Mougin, Vincent, Mousavi, Parsa, Mulita, Francesk, Mulu, Atsedemariam Andualem, Naghavi, Pirouz, Naik, Ganesh R, Nainu, Firzan, Nair, Tapas Sadasivan, Nargus, Shumaila, Negaresh, Mohammad, Nguyen, Hau Thi Hien, Nguyen, Dang H, Nguyen, Van Thanh, Nikolouzakis, Taxiarchis Konstantinos, Noman, Efaq Ali, Nri-Ezedi, Chisom Adaobi, Odetokun, Ismail A., Okwute, Patrick Godwin, Olana, Matifan Dereje, Olanipekun, Titilope O, Olasupo, Omotola O., Olivas-Martinez, Antonio, Ordak, Michal, Ortiz-Brizuela, Edgar, Ouyahia, Amel, Padubidri, Jagadish Rao, Pak, Anton, Pandey, Anamika, Pantazopoulos, Ioannis, Parija, Pragyan Paramita, Parikh, Romil R, Park, Seoyeon, Parthasarathi, Ashwaghosha, Pashaei, Ava, Peprah, Prince, Pham, Hoang Tran, Poddighe, Dimitri, Pollard, Andrew, Ponce-De-Leon, Alfredo, Prakash, Peralam Yegneswaran, Prates, Elton Junio Sady, Quan, Nguyen Khoi, Raee, Pourya, Rahim, Fakher, Rahman, Mosiur, Rahmati, Masoud, Ramasamy, Shakthi Kumaran, Ranjan, Shubham, Rao, Indu Ramachandra, Rashid, Ahmed Mustafa, Rattanavong, Sayaphet, Ravikumar, Nakul, Reddy, Murali Mohan Rama Krishna, Redwan, Elrashdy Moustafa Mohamed, Reiner, Robert C, Jr., Reyes, Luis Felipe, Roberts, Tamalee, Rodrigues, Mónica, Rosenthal, Victor Daniel, Roy, Priyanka, Runghien, Tilleye, Saeed, Umar, Saghazadeh, Amene, Saheb Sharif-Askari, Narjes, Saheb Sharif-Askari, Fatemeh, Sahoo, Soumya Swaroop, Sahu, Monalisha, Sakshaug, Joseph W, Salami, Afeez Abolarinwa, Saleh, Mohamed A., Salehi omran, Hossein, Sallam, Malik, Samadzadeh, Sara, Samodra, Yoseph Leonardo, Sanjeev, Rama Krishna, Sarasmita, Made Ary, Saravanan, Aswini, Sartorius, Benn, Saulam, Jennifer, Schumacher, Austin E, Seyedi, Seyed Arsalan, Shafie, Mahan, Shahid, Samiah, Sham, Sunder, Shamim, Muhammad Aaqib, Shamshirgaran, Mohammad Ali, Shastry, Rajesh P., Sherchan, Samendra P, Shiferaw, Desalegn, Shittu, Aminu, Siddig, Emmanuel Edwar, Sinto, Robert, Sood, Aayushi, Sorensen, Reed J D, Stergachis, Andy, Stoeva, Temenuga Zhekova, Swain, Chandan Kumar, Szarpak, Lukasz, Tamuzi, Jacques Lukenze, Temsah, Mohamad-Hani, Tessema, Melkamu B Tessema, Thangaraju, Pugazhenthan, Tran, Nghia Minh, Tran, Ngoc-Ha, Tumurkhuu, Munkhtuya, Ty, Sree Sudha, Udoakang, Aniefiok John, Ulhaq, Inam, Umar, Tungki Pratama, Umer, Abdurezak Adem, Vahabi, Seyed Mohammad, Vaithinathan, Asokan Govindaraj, Van den Eynde, Jef, Walson, Judd L, Waqas, Muhammad, Xing, Yuhan, Yadav, Mukesh Kumar, Yahya, Galal, Yon, Dong Keon, Zahedi Bialvaei, Abed, Zakham, Fathiah, Zeleke, Abyalew Mamuye, Zhai, Chunxia, Zhang, Zhaofeng, Zhang, Haijun, Zielińska, Magdalena, Zheng, Peng, Aravkin, Aleksandr Y, Vos, Theo, Hay, Simon I, Mosser, Jonathan F., Lim, Stephen S, Naghavi, Mohsen, Murray, Christopher J L, and Kyu, Hmwe Hmwe
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- 2024
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3. The burden and trend of diseases and their risk factors in Australia, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
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Islam, Sheikh Mohammed Shariful, Maddison, Ralph, Uddin, Riaz, Ball, Kylie, Livingstone, Katherine M, Khan, Asaduzzaman, Salmon, Jo, Ackerman, Ilana N, Adair, Tim, Adegboye, Oyelola A, Ademi, Zanfina, Adhikary, Ripon Kumar, Ahinkorah, Bright Opoku, Alam, Khurshid, Alene, Kefyalew Addis, Alif, Sheikh Mohammad, Amare, Azmeraw T, Ameyaw, Edward Kwabena, Aminde, Leopold N, Anderlini, Deanna, Angell, Blake, Ansar, Adnan, Antony, Benny, Anyasodor, Anayochukwu Edward, Arnet, Victoria Kiriaki, Astell-Burt, Thomas, Atorkey, Prince, Awoke, Mamaru Ayenew, Ayala Quintanilla, Beatriz Paulina, Ayano, Getinet, Bagheri, Nasser, Barnett, Anthony, Baune, Bernhard T, Bhandari, Dinesh, Bhaskar, Sonu, Biswas, Raaj Kishore, Borschmann, Rohan, Boufous, Soufiane, Briggs, Andrew M, Buchbinder, Rachelle, Bulamu, Norma B, Burns, Richard A, Carvalho, Andre F, Cerin, Ester, Cherbuin, Nicolas, Chowdhury, Enayet Karim, Ciobanu, Liliana G, Clark, Scott Richard, Cross, Marita, Dadi, Abel Fekadu, de Courten, Barbora, De Leo, Diego, de Luca, Katie, Doyle, Kerrie E, Edvardsson, David, Edvardsson, Kristina, Efendi, Ferry, Endalamaw, Aklilu, Fauk, Nelsensius Klau, Feng, Xiaoqi, Fitzgibbon, Bernadette Mary, Flavel, Joanne, Gebreyohannes, Eyob Alemayehu Alemayehu, Gesesew, Hailay Abrha, Gill, Tiffany K, Godinho, Myron Anthony, Gupta, Bhawna, Gupta, Vivek Kumar, Hambisa, Mitiku Teshome, Hamiduzzaman, Mohammad, Hankey, Graeme J, Hassanian-Moghaddam, Hossein, Hay, Simon I, Hebert, Jeffrey J, Huda, M Mamun, Huda, Tanvir M, Islam, M Mofizul, Islam, Mohammad Saidul, Islam, Rakibul M, Kaambwa, Billingsley, Kandel, Himal, Kassie, Gizat M, Kelly, Jaimon Terence, Kerr, Jessica A, Kiross, Girmay Tsegay, Knibbs, Luke D, Kulkarni, Vishnutheertha Vishnutheertha, Lalloo, Ratilal, Le, Long Khanh Dao, Leigh, James, Leung, Janni, Li, Shanshan, Mahumud, Rashidul Alam, Mamun, Abdullah A, Marzan, Melvin Barrientos, McGrath, John J, Mehlman, Max L, Meretoja, Atte, Mersha, Amanual Getnet, Miller, Ted R, Mitchell, Philip B, Mokdad, Ali H, Morawska, Lidia, Mpundu-Kaambwa, Christine, Mude, William, Murray, Christopher J L, Neupane Kandel, Sandhya, Nyanhanda, Tafadzwa, Obamiro, Kehinde O, Peden, Amy E, Pesudovs, Konrad, Polkinghorne, Kevan R, Rahman, Azizur, Rahman, Muhammad Aziz, Ratan, Zubair Ahmed, Rawal, Lal, Reifels, Lennart, Renzaho, Andre M N, Robinson, Stephen R, Roshandel, Danial, Rumisha, Susan Fred, Saunders, Paul A, Sawyer, Susan M, Schlaich, Markus P, Schutte, Aletta Elisabeth, Seidu, Abdul-Aziz, Sharma, Saurab, Shorofi, Seyed Afshin, Siabani, Soraya, Singh, Ambrish, Singh, Balbir Bagicha, Slater, Helen, Stephens, Jacqueline H, Stokes, Mark A, Subedi, Narayan Subedi, Sumi, Chandra Datta, Sun, Jing, Sundström, Johan, Szoeke, Cassandra E I, Tadakamadla, Santosh Kumar, Takahashi, Ken, Taylor, Jo, Tessema, Melkamu B Tessema, Thrift, Amanda G, To, Quyen G, Tollosa, Daniel Nigusse, Tran, Mai Thi Ngoc, Vandelanotte, Corneel, Varghese, Blesson Mathew, Veerman, Lennert J, Wang, Ning, Ward, Paul, Woodward, Mark, Wubishet, Befikadu Legesse, Xu, Xiaoyue, Ye, Pengpeng, Zaman, Sojib Bin, Zarghami, Amin, Zhang, Jianrong, and Crawford, David A
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- 2023
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4. Immunity against Moraxella catarrhalis requires guanylate‐binding proteins and caspase‐11‐NLRP3 inflammasomes
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Enosi Tuipulotu, Daniel, Feng, Shouya, Pandey, Abhimanu, Zhao, Anyang, Ngo, Chinh, Mathur, Anukriti, Lee, Jiwon, Shen, Cheng, Fox, Daniel, Xue, Yansong, Kay, Callum, Kirkby, Max, Lo Pilato, Jordan, Kaakoush, Nadeem O, Webb, Daryl, Rug, Melanie, Robertson, Avril AB, Tessema, Melkamu B, Pang, Stanley, Degrandi, Daniel, Pfeffer, Klaus, Augustyniak, Daria, Blumenthal, Antje, Miosge, Lisa A, Brüstle, Anne, Yamamoto, Masahiro, Reading, Patrick C, Burgio, Gaetan, and Man, Si Ming
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- 2023
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5. Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling
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Feng, Shouya, Enosi Tuipulotu, Daniel, Pandey, Abhimanu, Jing, Weidong, Shen, Cheng, Ngo, Chinh, Tessema, Melkamu B., Li, Fei-Ju, Fox, Daniel, Mathur, Anukriti, Zhao, Anyang, Wang, Runli, Pfeffer, Klaus, Degrandi, Daniel, Yamamoto, Masahiro, Reading, Patrick C., Burgio, Gaetan, and Man, Si Ming
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- 2022
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6. Mouse guanylate‐binding protein 1 does not mediate antiviral activity against influenza virus in vitro or in vivo
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Tessema, Melkamu B, primary, Tuipulotu, Daniel Enosi, additional, Oates, Clare V, additional, Brooks, Andrew G, additional, Man, Si Ming, additional, Londrigan, Sarah L, additional, and Reading, Patrick C, additional
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- 2023
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7. Expression of a Functional Mx1 Protein Is Essential for the Ability of RIG-I Agonist Prophylaxis to Provide Potent and Long-Lasting Protection in a Mouse Model of Influenza A Virus Infection
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Schwab, Lara S. U., primary, Villalón-Letelier, Fernando, additional, Tessema, Melkamu B., additional, Londrigan, Sarah L., additional, Brooks, Andrew G., additional, Hurt, Aeron, additional, Coch, Christoph, additional, Zillinger, Thomas, additional, Hartmann, Gunther, additional, and Reading, Patrick C., additional
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- 2022
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8. Mouse Mx1 Inhibits Herpes Simplex Virus Type 1 Genomic Replication and Late Gene ExpressionIn Vitroand Prevents Lesion Formation in the Mouse Zosteriform Model
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Tessema, Melkamu B., primary, Farrukee, Rubaiyea, additional, Andoniou, Christopher E., additional, Degli-Esposti, Mariapia A., additional, Oates, Clare V., additional, Barnes, James B., additional, Wakim, Linda M., additional, Brooks, Andrew G., additional, Londrigan, Sarah L., additional, and Reading, Patrick C., additional
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- 2022
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9. IFITM Proteins That Restrict the Early Stages of Respiratory Virus Infection Do Not Influence Late-Stage Replication
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Meischel, Tina, primary, Fritzlar, Svenja, additional, Villalon-Letelier, Fernando, additional, Tessema, Melkamu B., additional, Brooks, Andrew G., additional, Reading, Patrick C., additional, and Londrigan, Sarah L., additional
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- 2021
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10. Mouse Mx1 Inhibits Herpes Simplex Virus Type 1 Genomic Replication and Late Gene Expression In Vitro and Prevents Lesion Formation in the Mouse Zosteriform Model.
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Tessema, Melkamu B., Farrukee, Rubaiyea, Andoniou, Christopher E., Degli-Esposti, Mariapia A., Oates, Clare V., Barnes, James B., Wakim, Linda M., Brooks, Andrew G., Londrigan, Sarah L., and Reading, Patrick C.
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HUMAN herpesvirus 1 , *HERPES simplex virus , *GENE expression , *INFLUENZA , *HERPESVIRUS diseases , *LABORATORY mice , *DORSAL root ganglia , *ANIMAL disease models - Abstract
Myxovirus resistance (Mx) proteins are dynamin-like GTPases that are inducible by interferons (IFNs) following virus infections. Most studies investigating Mx proteins have focused on their activity against influenza A viruses (IAV), although emerging evidence suggests that some Mx proteins may exhibit broader antiviral activity. Herein, we demonstrate that in addition to IAV, overexpression of mouse Mx1 (mMx1), but not mMx2, resulted in potent inhibition of growth of the human alphaherpesviruses herpes simplex virus 1 (HSV-1) and HSV-2, whereas neither inhibited the mouse betaherpesvirus murine cytomegalovirus (MCMV) in vitro. IFN induction of a functional endogenous mMx1 in primary mouse fibroblasts ex vivo was also associated with inhibition of HSV-1 growth. Using an in vitro overexpression approach, we demonstrate that mutations that result in redistribution of mMx1 from the nucleus to the cytoplasm or in loss of its combined GTP binding and GTPase activity also abrogated its ability to inhibit HSV-1 growth. Overexpressed mMx1 did not inhibit early HSV-1 gene expression but was shown to inhibit both replication of the HSV-1 genome as well as subsequent late gene expression. In a mouse model of cutaneous HSV-1 infection, mice expressing a functional endogenous mMx1 showed significant reductions in the severity of skin lesions as well as reduced HSV-1 titers in both the skin and dorsal root ganglia (DRG). Together, these data demonstrate that mMx1 mediates potent antiviral activity against human alphaherpesviruses by blocking replication of the viral genome and subsequent steps in virus replication. Moreover, endogenous mMx1 potently inhibited pathogenesis in the zosteriform mouse model of HSV-1 infection. IMPORTANCE While a number of studies have demonstrated that human Mx proteins can inhibit particular herpesviruses in vitro, we are the first to report the antiviral activity of mouse Mx1 (mMx1) against alphaherpesviruses both in vitro and in vivo. We demonstrate that both overexpressed mMx1 and endogenous mMx1 potently restrict HSV-1 growth in vitro. mMx1-mediated inhibition of HSV-1 was not associated with inhibition of virus entry and/or import of the viral genome into the nucleus, but rather with inhibition of HSV-1 genomic replication as well as subsequent late gene expression. Therefore, inhibition of human alphaherpesviruses by mMx1 occurs by a mechanism that is distinct from that reported for human Mx proteins against herpesviruses. Importantly, we also provide evidence that expression of a functional endogenous mMx1 can limit HSV-1 pathogenesis in a mouse model of infection. [ABSTRACT FROM AUTHOR]
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- 2022
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11. Preterm piglets as a translational model for premature babies: focus on hepatic drug metabolism
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Buyssens, Laura A., primary, Tessema, Melkamu B., additional, Ayuso, Miriam, additional, Van Ginneken, Chris J., additional, and Van Cruchten, Steven J., additional
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- 2018
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