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2. Hydroxychloroquine in mild-to-moderate coronavirus disease 2019: a placebo-controlled double blind trial

Author

Brangier, Antoine, Codron, Philippe, Lemée, Jean Michel, Pichon, Virginie, Dhersin, Robin, Urbanski, Geoffrey, Lavigne, Christian, Courtois, Roxane, Danielou, Hélène, Lebreton, Jonathan, Vatan, Rémi, Crochette, Nicolas, Lainé, Jean-Baptiste, Perez, Lucia, Blanchi, Sophie, Hitoto, Hikombo, Bernard, Louis, Maillot, François, Marchand Adam, Sylvain, Talarmin, Jean-Philippe, Gaigneux, Emeline, Motte-Vincent, Pauline, Morrier, Marine, Merrien, Dominique, Bleher, Yves, Flori, Maxime, Ducet-Boiffard, Amélie, Colin, Orane, Février, Ronan, Thill, Pauline, Tetart, Macha, Demaeght, François, Lafond-Desmurs, Barthelemy, Pradier, Maxime, Meybeck, Agnes, Picaud, Marjorie, Prazuck, Thierry, Chapelet, Guillaume, Rouaud, Agnès, Le Turnier, Paul, Sunder, Simon, Lorleac'h, Aurélien, Dollon, Christophe, Jacquet, Antoine, Le Vely, Francois, Gazeau, Pierre, Ansart, Séverine, Roger, Hélène, Laterza, François, Buzelé, Rodolphe, Tahmi, Fella, Lepeule, Raphael, Lacombe, Karine, Lefebvre, Bénédicte, Célarier, Thomas, Gagneux-Brunon, Amandine, Botelho-Nevers, Elisabeth, Bernard, Marc, Garnier, Camille, Mourguet, Morgane, Pugnet, Gregory, Vienne-Noyes, Sara, Martin-Blondel, Guillaume, Delobel, Pierre, Grouteau, Gaspard, Debard, Alexa, Guilleminault, Laurent, Arias, Pauline, Chakvetadze, Catherine, Flateau, Clara, Kopp, Aude, Putot, Alain, Barben, Jeremy, Mouries Martin, Suzanne, Nuss, Valentine, Piroth, Lionel, Claessens, Yann-Erick, Hentgen, Veronique, Martinot, Martin, Bach-Bunner, Maxime, Bonijoly, Thomas, Gravier, Simon, Michel, Jean-Marc, Andreu, Mathilde, Roriz, Mélanie, Baldolli, Aurélie, Brochard, Julia, Grossi, Olivier, Pineau, Samuel, Brisset, Josselin, Desvaux, Edouard, Gondran, Guillaume, Faucher, Jean-François, Quesnel, Paul-Antoine, Bezanahary, Holy, Danthu, Clément, Gutierrez, Blandine, Ly, Kim, Simonneau, Yannick, Cypierre, Anne, Pinet, Pauline, Durox, Hélène, Ducroix-Roubertou, Sophie, Genet, Claire, Beraud, Guillaume, Le Moal, Gwenael, Rammaert, Blandine, Lanoix, Jean-Philippe, Andrejak, Claire, Joseph, Cédric, Soriot-Thomas, Sandrine, Dhote, Robin, Abad, Sébastien, Benainous, Ruben, Boitiaux, Jean-François, Briend, Guillaume, Gonfroy, Celine, Harent, Stanislas, Lagrange, Aurore, Tone, Alina, Wayenberg, Laura, Desoutter, Sophie, Ettahar, Nicolas, Gey, Thomas, Leroy, Vincent, Gaillard, Sacha, Toma, Andrea, Broussier, Amaury, Etienne, Sandrine, Spivac, Yann, Martha, Benoit, Roch, Nathalie, Diaz, Pierre, N’guyen Baranoff, Danièle, Rebaudet, Stanislas, Jourda, François, Zeller, Valérie, Bienvenu, Boris, Boyer, Arnaud, Pellier, Isabelle, Mercat, Alain, Darsonval, Astrid, Blanchet, Odile, Custaud, Marc-Antoine, Lefeuvre, Caroline, Parot-Schinkel, Elsa, Vielle, Bruno, Briet, Marie, Roy, Pierre-Marie, Dubée, Vincent, Guidet, Bertrand, Mismetti, Patrick, Vicaut, Eric, Sanchez, Olivier, Girard, Philippe, Elias, Antoine, Couturaud, Francis, Gable, Béatrice, Lazareff, Sybille, Carballido, Loïc, Hue, Catherine, Chrétien, Jean-Marie, Goraguer, Adrien, Eeckhoutte, Lucie van, Abbara, Chadi, Boucher, Sophie, Devaud, Edouard, Robineau, Olivier, Rispal, Patrick, Guimard, Thomas, d’Anglejean, Emma, and Diamantis, Sylvain

Published
2021
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3. Corticosteroids in patients hospitalized for COVID-19 pneumonia who require oxygen: observational comparative study using routine care data

Author

Lescure, François-Xavier, Tran, Viet-Thi, Mahévas, Matthieu, Bani-Sadr, Firouze, Robineau, Olivier, Perpoint, Thomas, Perrodeau, Elodie, Gallay, Laure, Ravaud, Philippe, Goehringer, François, Ismaël, Sophie, Laouénan, Cédric, Soulier, Jennifer, Puéchal, Oriane, D’Ortenzio, Eric, Yazdanpanah, Yazdan, Maulin, Laurence, Martinez, Stéphanie, Sanderink, Diane, Fialaire, Pascale, Ansart, Séverine, Perez, Lucas, Destrem, Anne - Laure, Moulin, Chloé, Gicquel, Pascal, Rivière, Frédéric, Martinot, Martin, Zadeh, Mahsa Mohseni, Chroboczek, Tomasz, Belval, Thibaut Challan, Piroth, Lionel, Sixt, Thibault, Moretto, Florian, Cabié, André, Pasquier, Jérémie, Cabras, Ornella, Morrier, Marine, Reuter, Jean, Henin, Thomas, Braquet, Pierre, Desmurs-Clavel, Helene, Hot, Arnaud, Bienvenu, Boris, Asselate, Belkacem, Vignier, Nicolas, Nguala, Steve, Diamantis, Sylvain, Frémont, Guillemette, Nivose, Pierre Louis, Thiébaut, Mathilde, Lefevre, Benjamin, Auge, Hélène, le Turnier, Paul, Benkalfate, Naila, Grossi, Olivier, Pineau, Samuel, Demonchy, Elisa, Merindol, Julie, Durand, Claire, Tieulié, Nathalie, Queyrel, Viviane, Laureillard, Didier, Loubet, Paul, Greffe, Ségolène, Dournon, Nathalie, Kassim, Youssouf Mohamed, Gourjault, Cyrille, Lahens, Alexandre, Legendre, Paul, Morbieu, Caroline, Mahevas, Matthieu, Melica, Giovanna, Levièvre, Jean-Daniel, Schlemmer, Frédéric, Tunesi, Simone, Leblanc, Claire, Bourgarit-Durand, Anne, Bleibtreu, Alexandre, Tebano, Gianpiero, Pacanowski, Jérôme, Zabbe, Jean-Benoit, Devaux, Mathilde, Bellec, Laurent, Gosset-Woimant, Marine, Lambert, Céleste, Hentzien, Maxime, Servettaz, Amélie, Alexandre, Kevin, Etienne, Manuel, Leguillon, Romain, Dollat, Marion, Lefrancois, Rémi, Pouvaret, Anne, Ruch, Yvon, Dieudonné, Yannick, Martin-Blondel, Guillaume, Boumaza, Xavier, Lafaurie, Margaux, Tetart, Macha, Lemaignen, Adrien, Ferreira-Maldent, Nicole, Duréault, Amélie, Gousseff, Marie, Chantepie, Claire, Bisio, Francesca, Pommeret, Fanny, Blamble, Emeline Colomba, and Somohano, Claire Ara

Published
2021
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6. Are unknown co-medications, over-the-counter and off-label drug use still problems among people living with HIV? Results from a transversal survey in 23 centres in France.

Author

Tetart, Macha, Passecountrin, Priscila, Lesourd, Anaïs, Sanderink, Diane, Moal, Gwenaël Le, Surgers, Laure, Beraud, Guillaume, Katlama, Christine, Robineau, Olivier, Parienti, Jean-Jacques, and group, the COMEDWEEK Study

Subjects
*HIV-positive persons, *OFF-label use (Drugs), *DRUG interactions, *PROTON pump inhibitors, *INTEGRASE inhibitors, *MULTIHOSPITAL systems
Abstract

Introduction Polypharmacy can lead to drug–drug interactions (DDIs), especially with ART. The burden of co-medications, including over-the-counter (OTC) drugs and self-medications, could be underestimated. We aimed to investigate the proportion of people living with HIV (PLHIV) with declared and undeclared co-medications, as well as their potential burden. Methods We conducted a national, multicentre, 1 week cross-sectional study between 10 December and 16 December 2019 in 23 French hospitals amongst consecutive adult PLHIV presenting for a routine outpatient visit. A standardized questionnaire filled in by the physicians assessed all medications and other active chemical substances taken by the PLHIV. Results Overall we enrolled 496 participants from 23 centres. Median age was 50.6 years; ART regimens included an integrase inhibitor in 61% (n  = 302), an NNRTI in 34% (n  = 169) and a PI in 14% (n  = 70) of the cases. Co-medications involved 392 (79%) PLHIV, among which 85 (17%) received polypharmacy (≥5 medications). Previously unknown co-medications or other active substances were found for 32% (n  = 159) of the participants. Corticosteroids (9%, n  = 46) and proton pump inhibitors (10%, n  = 50) were frequently administered. These co-medications did not differ according to age range. Illegal drug use was declared by 11% (n  = 54) and OTC drugs by 23% (n  = 113) of PLHIV. Potential DDIs were discovered for 11% (n  = 53), leading to treatment modifications in 47% (25/53) of cases. Conclusions Potential DDIs that lead to therapeutic modifications remain significant whatever the age of PLHIV. More devoted time to identify co-medications and OTC treatment is needed in all PLHIV. [ABSTRACT FROM AUTHOR]

Published
2023
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7. Rifabutin versus rifampicin bactericidal and antibiofilm activities against clinical strains of Staphylococcus spp. isolated from bone and joint infections

Author

Thill, Pauline, primary, Robineau, Olivier, additional, Roosen, Gabrielle, additional, Patoz, Pierre, additional, Gachet, Benoit, additional, Lafon-Desmurs, Barthélémy, additional, Tetart, Macha, additional, Nadji, Safia, additional, Senneville, Eric, additional, and Blondiaux, Nicolas, additional

Published
2022
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8. Hydroxychloroquine in mild-to-moderate coronavirus disease 2019: a placebo-controlled double blind trial

Author

Dubée, Vincent, primary, Roy, Pierre-Marie, additional, Vielle, Bruno, additional, Parot-Schinkel, Elsa, additional, Blanchet, Odile, additional, Darsonval, Astrid, additional, Lefeuvre, Caroline, additional, Abbara, Chadi, additional, Boucher, Sophie, additional, Devaud, Edouard, additional, Robineau, Olivier, additional, Rispal, Patrick, additional, Guimard, Thomas, additional, d’Anglejean, Emma, additional, Diamantis, Sylvain, additional, Custaud, Marc-Antoine, additional, Pellier, Isabelle, additional, Mercat, Alain, additional, Brangier, Antoine, additional, Codron, Philippe, additional, Lemée, Jean Michel, additional, Pichon, Virginie, additional, Dhersin, Robin, additional, Urbanski, Geoffrey, additional, Lavigne, Christian, additional, Courtois, Roxane, additional, Danielou, Hélène, additional, Lebreton, Jonathan, additional, Vatan, Rémi, additional, Crochette, Nicolas, additional, Lainé, Jean-Baptiste, additional, Perez, Lucia, additional, Blanchi, Sophie, additional, Hitoto, Hikombo, additional, Bernard, Louis, additional, Maillot, François, additional, Marchand Adam, Sylvain, additional, Talarmin, Jean-Philippe, additional, Gaigneux, Emeline, additional, Motte-Vincent, Pauline, additional, Morrier, Marine, additional, Merrien, Dominique, additional, Bleher, Yves, additional, Flori, Maxime, additional, Ducet-Boiffard, Amélie, additional, Colin, Orane, additional, Février, Ronan, additional, Thill, Pauline, additional, Tetart, Macha, additional, Demaeght, François, additional, Lafond-Desmurs, Barthelemy, additional, Pradier, Maxime, additional, Meybeck, Agnes, additional, Picaud, Marjorie, additional, Prazuck, Thierry, additional, Chapelet, Guillaume, additional, Rouaud, Agnès, additional, Le Turnier, Paul, additional, Sunder, Simon, additional, Lorleac'h, Aurélien, additional, Dollon, Christophe, additional, Jacquet, Antoine, additional, Le Vely, Francois, additional, Gazeau, Pierre, additional, Ansart, Séverine, additional, Roger, Hélène, additional, Laterza, François, additional, Buzelé, Rodolphe, additional, Tahmi, Fella, additional, Lepeule, Raphael, additional, Lacombe, Karine, additional, Lefebvre, Bénédicte, additional, Célarier, Thomas, additional, Gagneux-Brunon, Amandine, additional, Botelho-Nevers, Elisabeth, additional, Bernard, Marc, additional, Garnier, Camille, additional, Mourguet, Morgane, additional, Pugnet, Gregory, additional, Vienne-Noyes, Sara, additional, Martin-Blondel, Guillaume, additional, Delobel, Pierre, additional, Grouteau, Gaspard, additional, Debard, Alexa, additional, Guilleminault, Laurent, additional, Arias, Pauline, additional, Chakvetadze, Catherine, additional, Flateau, Clara, additional, Kopp, Aude, additional, Putot, Alain, additional, Barben, Jeremy, additional, Mouries Martin, Suzanne, additional, Nuss, Valentine, additional, Piroth, Lionel, additional, Claessens, Yann-Erick, additional, Hentgen, Veronique, additional, Martinot, Martin, additional, Bach-Bunner, Maxime, additional, Bonijoly, Thomas, additional, Gravier, Simon, additional, Michel, Jean-Marc, additional, Andreu, Mathilde, additional, Roriz, Mélanie, additional, Baldolli, Aurélie, additional, Brochard, Julia, additional, Grossi, Olivier, additional, Pineau, Samuel, additional, Brisset, Josselin, additional, Desvaux, Edouard, additional, Gondran, Guillaume, additional, Faucher, Jean-François, additional, Quesnel, Paul-Antoine, additional, Bezanahary, Holy, additional, Danthu, Clément, additional, Gutierrez, Blandine, additional, Ly, Kim, additional, Simonneau, Yannick, additional, Cypierre, Anne, additional, Pinet, Pauline, additional, Durox, Hélène, additional, Ducroix-Roubertou, Sophie, additional, Genet, Claire, additional, Beraud, Guillaume, additional, Le Moal, Gwenael, additional, Rammaert, Blandine, additional, Lanoix, Jean-Philippe, additional, Andrejak, Claire, additional, Joseph, Cédric, additional, Soriot-Thomas, Sandrine, additional, Dhote, Robin, additional, Abad, Sébastien, additional, Benainous, Ruben, additional, Boitiaux, Jean-François, additional, Briend, Guillaume, additional, Gonfroy, Celine, additional, Harent, Stanislas, additional, Lagrange, Aurore, additional, Tone, Alina, additional, Wayenberg, Laura, additional, Desoutter, Sophie, additional, Ettahar, Nicolas, additional, Gey, Thomas, additional, Leroy, Vincent, additional, Gaillard, Sacha, additional, Toma, Andrea, additional, Broussier, Amaury, additional, Etienne, Sandrine, additional, Spivac, Yann, additional, Martha, Benoit, additional, Roch, Nathalie, additional, Diaz, Pierre, additional, N’guyen Baranoff, Danièle, additional, Rebaudet, Stanislas, additional, Jourda, François, additional, Zeller, Valérie, additional, Bienvenu, Boris, additional, Boyer, Arnaud, additional, Briet, Marie, additional, Dubée, Vincent, additional, Guidet, Bertrand, additional, Mismetti, Patrick, additional, Vicaut, Eric, additional, Sanchez, Olivier, additional, Girard, Philippe, additional, Elias, Antoine, additional, Couturaud, Francis, additional, Gable, Béatrice, additional, Lazareff, Sybille, additional, Carballido, Loïc, additional, Hue, Catherine, additional, Chrétien, Jean-Marie, additional, Goraguer, Adrien, additional, and Eeckhoutte, Lucie van, additional

Published
2021
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9. A disseminated Mycobacterium marinum infection in a renal transplant HIV-infected patient successfully treated with a bedaquiline-containing antimycobacterial treatment: A case report

Author

Meybeck, Agnès, primary, Tetart, Macha, additional, Baclet, Véronique, additional, Alcaraz, Isabelle, additional, Blondiaux, Nicolas, additional, Peytavin, Gilles, additional, Veziris, Nicolas, additional, Robineau, Olivier, additional, and Senneville, Eric, additional

Published
2021
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10. Corticosteroids in patients hospitalized for COVID-19 pneumonia who require oxygen: observational comparative study using routine care data

Author

Tran, Viet-Thi, primary, Mahévas, Matthieu, additional, Bani-Sadr, Firouze, additional, Robineau, Olivier, additional, Perpoint, Thomas, additional, Perrodeau, Elodie, additional, Gallay, Laure, additional, Ravaud, Philippe, additional, Goehringer, François, additional, Lescure, François-Xavier, additional, Tran, Viet-Thi, additional, Ismaël, Sophie, additional, Laouénan, Cédric, additional, Soulier, Jennifer, additional, Puéchal, Oriane, additional, D’Ortenzio, Eric, additional, Yazdanpanah, Yazdan, additional, Maulin, Laurence, additional, Martinez, Stéphanie, additional, Sanderink, Diane, additional, Fialaire, Pascale, additional, Ansart, Séverine, additional, Perez, Lucas, additional, Destrem, Anne - Laure, additional, Moulin, Chloé, additional, Gicquel, Pascal, additional, Rivière, Frédéric, additional, Martinot, Martin, additional, Zadeh, Mahsa Mohseni, additional, Chroboczek, Tomasz, additional, Belval, Thibaut Challan, additional, Piroth, Lionel, additional, Sixt, Thibault, additional, Moretto, Florian, additional, Cabié, André, additional, Pasquier, Jérémie, additional, Cabras, Ornella, additional, Morrier, Marine, additional, Reuter, Jean, additional, Henin, Thomas, additional, Braquet, Pierre, additional, Desmurs-Clavel, Helene, additional, Hot, Arnaud, additional, Bienvenu, Boris, additional, Asselate, Belkacem, additional, Vignier, Nicolas, additional, Nguala, Steve, additional, Diamantis, Sylvain, additional, Frémont, Guillemette, additional, Nivose, Pierre Louis, additional, Thiébaut, Mathilde, additional, Lefevre, Benjamin, additional, Auge, Hélène, additional, le Turnier, Paul, additional, Benkalfate, Naila, additional, Grossi, Olivier, additional, Pineau, Samuel, additional, Demonchy, Elisa, additional, Merindol, Julie, additional, Durand, Claire, additional, Tieulié, Nathalie, additional, Queyrel, Viviane, additional, Laureillard, Didier, additional, Loubet, Paul, additional, Greffe, Ségolène, additional, Dournon, Nathalie, additional, Kassim, Youssouf Mohamed, additional, Gourjault, Cyrille, additional, Lahens, Alexandre, additional, Legendre, Paul, additional, Morbieu, Caroline, additional, Mahevas, Matthieu, additional, Melica, Giovanna, additional, Levièvre, Jean-Daniel, additional, Schlemmer, Frédéric, additional, Tunesi, Simone, additional, Leblanc, Claire, additional, Bourgarit-Durand, Anne, additional, Bleibtreu, Alexandre, additional, Tebano, Gianpiero, additional, Pacanowski, Jérôme, additional, Zabbe, Jean-Benoit, additional, Devaux, Mathilde, additional, Bellec, Laurent, additional, Gosset-Woimant, Marine, additional, Lambert, Céleste, additional, Hentzien, Maxime, additional, Servettaz, Amélie, additional, Alexandre, Kevin, additional, Etienne, Manuel, additional, Leguillon, Romain, additional, Dollat, Marion, additional, Lefrancois, Rémi, additional, Pouvaret, Anne, additional, Ruch, Yvon, additional, Dieudonné, Yannick, additional, Martin-Blondel, Guillaume, additional, Boumaza, Xavier, additional, Lafaurie, Margaux, additional, Tetart, Macha, additional, Lemaignen, Adrien, additional, Ferreira-Maldent, Nicole, additional, Duréault, Amélie, additional, Gousseff, Marie, additional, Chantepie, Claire, additional, Bisio, Francesca, additional, Pommeret, Fanny, additional, Blamble, Emeline Colomba, additional, and Somohano, Claire Ara, additional

Published
2021
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14. The Links Between Sleep Apnea and Chronic Kidney Disease

Author

Balint Gib, Marius, Aron, Christophe, Ilie, Svetlana, Wallyn, Frederic, Tetart, Macha, and Balint Gib, Dumitrita

Abstract

Recent research suggests an association between the development and progression of chronic kidney disease (CKD) - which affects 10–13% of the general population and leads to high rates of morbidity - and sleep apnea (SA). SA impacts 2–4% of middle aged adults through one of its three forms: obstructive (OSA), central (CSA) and mixed sleep apnea, respectively. SA is associated with sleep fragmentation and hypoxemia during the apneic phenomena. Sleep fragmentation activates the renin-angiotensin-aldosterone system and the sympathetic nervous system, and alters the cardiovascular hemodynamic. It also results in the production of free radicals. SA is a risk factor for CKD progression because it is associated with glomerular hyper-filtration and may be an independent predictor of proteinuria. More specifically, the treatment of sleep apnea, manifested through one of its three forms - obstructive, central, and mixed, respectively - can reduce the severity of CKD and delay its progression by reducing CKD risk factors. This paper discusses the mechanisms that link CKD and sleep apnea, and suggests SA treatments with beneficial effects to CKD-related cases. Optimizing sleep duration and quality and treating sleep disorders, especially SA, we can reduce the severity of CKD and the delay of progression.

Published
2015

15. Infectious diarrhea of adults and children

Author

Tetart M and Alfandari S

Subjects
Adult, Child, Humans, Infant, Diarrhea
Abstract

Competing Interests: S. Alfandari déclare participer ou avoir participé à des interventions ponctuelles pour l’entreprise Gilead (action de formation), MSD (action de formation, conseil), Novartis (action de formation), Pfizer (action de formation) ; et avoir été pris en charge (transport, hôtel, repas), à l’occasion de déplacement pour congrès, par Astellas, Gilead, MSD, Novex et Pfizer. M. Tetart n'a pas fourni de déclaration de lien d'intérêts.

Published
2017

16. Decision algorithm for infectious diarrhea

Author

Tetart M and Alfandari S

Subjects
Algorithms, Humans, Decision Making, Diarrhea therapy
Abstract

Competing Interests: S. Alfandari déclare participer ou avoir participé à des interventions ponctuelles pour l’entreprise Gilead (action de formation), MSD (action de formation, conseil), Novartis (action de formation), Pfizer (action de formation) ; et avoir été pris en charge (transport, hôtel, repas), à l’occasion de déplacement pour congrès, par Astellas, Gilead, MSD, Novex et Pfizer. M. Tetart n'a pas fourni de déclaration de lien d'intérêts.

Published
2017

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