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Amaç: Yeni Coronavirus 2019 hastalarının gözyaşlarında Severe Acute Respiratory Syndrome Coronavirus-2 RNA’sının varlığını tespit etmeyi amaçladık.Gereç ve Yöntem: Bu prospektif çalışma Sağlık Bilimleri Üniversitesi Kartal Dr. Lütfi Kırdar Şehir Hastanesi’nde 13-21 Mayıs 2020 tarihleri arasında gerçekleştirildi. Real-time polimeraz zincir reaksiyonu testi için yeni Coronavirus 2019 hastalığı olan 15 hastanın nazofarengeal ve gözyaşı örnekleri alındı. Oküler ve sistemik belirti ve bulgular, göğüs bilgisayarlı tomografi taramaları ve tedavi için kullanılan ilaçların yanı sıra laboratuvar testlerinin sonuçları kaydedildi.Bulgular: Onbeş hastanın dokuzu (60%) erkek, altısı (40%) kadındı. Hastaların ortalama yaşı 53.86±20.20 (21-89) idi. Dokuz hastanın (60%) nazofarengeal örneklerinde yeni Coronavirus 2019 hastalığı için real-time polimeraz zincir reaksiyon testi pozitifti. Hiçbir hastanın gözyaşı örneğinde Severe Acute Respiratory Syndrome Coronavirus-2 real-time polimeraz zincir reaksiyon testi pozitif değildi. Onbeş hastanın sadece ikisinde bilateral konjonktivit mevcuttu. Bu iki hastanın nazofarengeal örneklerinde Severe Acute Respiratory Syndrome Coronavirus-2 real-time polimeraz zincir reaksiyon testinin sonucu pozitifti.Sonuç: Bu çalışmada oküler belirti ve bulgusu olsun ya da olmasın yeni Coronavirus 2019 hastalarının gözyaşı örneklerinde Severe Acute Respiratory Syndrome Coronavirus-2 RNA tespit edilememiştir., Aim: We aimed to detect the presence of Severe Acute Respiratory Syndrome Coronavirus-2 RNA in the tears of patients with confirmed novel Coronavirus disease 2019.Materials and Methods: This prospective study was performed at Health Science University Kartal Dr. Lutfi Kırdar City Hospital between 13-21 May 2020. Nasopharyngeal and tear samples of 15 patients with novel Coronavirus disease 2019 was performed for real-time polymerase chain reaction assay. Ocular and systemic signs and symptoms, chest computed tomographic scans, and results of laboratory blood tests as well as the drugs used for the treatment were noted and analyzed.Results: Of the 15 patients nine (60%) were male and six (40%) were female. Mean age of the patients was 53.86±20.20 (21-89) years. Among them nine patients (60%) were positive for novel coronavirus disease 2019 on real-time polymerase chain reaction from nasopharyngeal specimens. None of the patients was positive for real-time polymerase chain reaction for Severe Acute Respiratory Syndrome Coronavirus-2 in tear specimens. Only two of 15 patients had bilateral conjunctivitis. These two patients had positive results for Severe Acute Respiratory Syndrome Coronavirus-2 on real-time polymerase chain reaction from nasopharyngeal swabs.Conclusion: In this study Severe Acute Respiratory Syndrome Coronavirus-2 RNA could not be detected in the tear samples of the patients with confirmed novel Coronavirus disease 2019 with or without ocular symptoms and signs.

Purpose Methods and materials Results Conclusion Personal information and conflict of interest References, Purpose: With the widespread use of contrast-enhanced magnetic resonance imaging (MRI) examinations, developmental venous anomalies (DVA) have become the most commonly diagnosed intracranial vascular malformations. Incidentally detected DVAs may be usually...

Introduction: COVID-19 disease caused by the SARS-Cov-2 virus is characterized by clinical spectra of varying severity. Coagulopathy and inflammation are the most important factors associated with COVID-19 severity. The use of a biomarker of inflammation and coagulation factors has not yet been clarified. The present study aimed to examine the role of CRP/Albumin, an inflammation marker, in predicting the course of COVID-19 disease.Methods: The Demographic, laboratory, and prognosis of 457 patients who were hospitalized during the COVID-19 pandemic service between April and May 2020 were analyzed retrospectively. The relationship between the patients' CRP/Albumin ratio and disease severity, length of hospital stays, and prognosis were analyzed.Results: The rate of hospitalization in the intensive care unit was 10.5% (n=48), mechanical ventilation was 8.1% (n=37), and death was 1.3% (n=6). The CRP/albumin ratio was statistically higher in those with lung infiltration (p=0.005), those who were taken to the intensive care unit (p, Giriş: SARS-Cov-2 virüsünün neden olduğu COVID-19 hastalığı farklı şiddette klinik spektrumlar ile karakterize edilmiştir. Koagülopati ve inflamasyon COVID-19 şiddeti ile ilişkili en önemli faktörlerdir. Enflamasyon ve pıhtılaşma faktörlerinin biyobelirteç kullanımı henüz netleştirilememiştir. Mevcut çalışma inflamasyon belirteci olan CRP/Albümin düzeyinin COVID-19 hastalık seyrinin tahminindeki rolünü incelemeyi amaçlamıştır.Yöntem: Pandemi servisinde Nisan-Mayıs 2020 tarihleri arasında yatarak tedavi gören 457 COVID-19 hastasının demografik, laboratuvar ve hastalık seyirleri retrospektif olarak analiz edildi. Hastaların CRP/Albümin oranı ile hastalık şiddeti, hastanede kalış süresi ve prognoz arasındaki ilişki analiz edildi.Bulgular: Hastaların yoğun bakıma yatış oranı %10,5 (n=48), mekanik ventilasyon ihtiyacı %8,1 (n=37) ve ölüm oranı %1,3 (n=6) idi. Akciğer infiltrasyonu olanlarda (p=0,005), yoğun bakıma alınanlarda (p

© 2022 College of Physicians and Surgeons Pakistan. All rights reserved.Objective: To compare the detection of transthoracic tru-cut biopsy performed on metabolically active areas in positron emission tomography (PET) for the diagnosis of lung cancer, compared to only CT scan-guided biopsy. Study Design: Descriptive study. Place and Duration of Study: Department of Thoracic Surgery, Kayseri City Training and Research Hospital, Turkey, between December 2020 to June 2021. Methodology: Patients of suspected lung cancer with pre-transthoracic biopsy chest computerised tomography and without positron emission tomography were included in Group A; while, patients with both and positron emission tomography chest computerised tomography were included in Group B. Based on the CT findings of the patients in Group A, a biopsy was obtained from the most appropriate place. The patients in Group B were evaluated by a nuclear medicine specialist and the place with the highest maximum standardised uptake value before the biopsy was marked and the area to be biopsied was determined. Results: The malignancy detection rate was significantly higher in Group B (48/50 patients, 96%) than in Group A (36/50 patients, 72%, p=0.001). Two lesions in the Group B (4 %) and 14 lesions in the Group A (28 %) were found to give benign results (p=0.001). Biopsy was repeated in one patient of Group B, and in five patients of Group A due to an initial negative diagnosis. The sensitivity of PET/CT in predicting malignant tumor was 96%, with the positive predictive value (PPV) of 98.0%; while the sensitivity of CT was 74.5%, with PPV of 82%. Conclusion: Transthoracic biopsies taken by considering metabolically active areas of the mass in positron emission tomography-guided can both increase diagnosis rate and reduce the complication rate by preventing repeated biopsies.