Author: "Thai H" - Searchworks@Jio Institute Digital Library Search Results

1,436 results on '"Thai H"'

1. SETD2 loss in renal epithelial cells drives epithelial‐to‐mesenchymal transition in a TGF‐β‐independent manner

Author: Tianchu Wang, Ryan T. Wagner, Ryan A. Hlady, Xiaoyu Pan, Xia Zhao, Sungho Kim, Liguo Wang, Jeong‐Heon Lee, Huijun Luo, Erik P. Castle, Douglas F. Lake, Thai H. Ho, and Keith D. Robertson
Subjects: clear cell renal cell carcinoma, epithelial‐to‐mesenchymal transition, histone H3 lysine 36 trimethylation, paracrine signaling, SETD2 mutation, transcription factors, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Histone‐lysine N‐methyltransferase SETD2 (SETD2), the sole histone methyltransferase that catalyzes trimethylation of lysine 36 on histone H3 (H3K36me3), is often mutated in clear cell renal cell carcinoma (ccRCC). SETD2 mutation and/or loss of H3K36me3 is linked to metastasis and poor outcome in ccRCC patients. Epithelial‐to‐mesenchymal transition (EMT) is a major pathway that drives invasion and metastasis in various cancer types. Here, using novel kidney epithelial cell lines isogenic for SETD2, we discovered that SETD2 inactivation drives EMT and promotes migration, invasion, and stemness in a transforming growth factor‐beta‐independent manner. This newly identified EMT program is triggered in part through secreted factors, including cytokines and growth factors, and through transcriptional reprogramming. RNA‐seq and assay for transposase‐accessible chromatin sequencing uncovered key transcription factors upregulated upon SETD2 loss, including SOX2, POU2F2 (OCT2), and PRRX1, that could individually drive EMT and stemness phenotypes in SETD2 wild‐type (WT) cells. Public expression data from SETD2 WT/mutant ccRCC support the EMT transcriptional signatures derived from cell line models. In summary, our studies reveal that SETD2 is a key regulator of EMT phenotypes through cell‐intrinsic and cell‐extrinsic mechanisms that help explain the association between SETD2 loss and ccRCC metastasis.
Published: 2024
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2. The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

Author: Christopher J. Ricketts, Aguirre A. De Cubas, Huihui Fan, Christof C. Smith, Martin Lang, Ed Reznik, Reanne Bowlby, Ewan A. Gibb, Rehan Akbani, Rameen Beroukhim, Donald P. Bottaro, Toni K. Choueiri, Richard A. Gibbs, Andrew K. Godwin, Scott Haake, A. Ari Hakimi, Elizabeth P. Henske, James J. Hsieh, Thai H. Ho, Rupa S. Kanchi, Bhavani Krishnan, David J. Kwiatkowski, Wenbin Liu, Maria J. Merino, Gordon B. Mills, Jerome Myers, Michael L. Nickerson, Victor E. Reuter, Laura S. Schmidt, C. Simon Shelley, Hui Shen, Brian Shuch, Sabina Signoretti, Ramaprasad Srinivasan, Pheroze Tamboli, George Thomas, Benjamin G. Vincent, Cathy D. Vocke, David A. Wheeler, Lixing Yang, William Y. Kim, A. Gordon Robertson, Paul T. Spellman, W. Kimryn Rathmell, and W. Marston Linehan
Subjects: Biology (General), QH301-705.5
Published: 2024
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3. Cancer associated macrophage-like cells in metastatic renal cell carcinoma predicts for poor prognosis and tracks treatment response in real time

Author: Amama Ali, Daniel L. Adams, Dimpal M. Kasabwala, Cha-Mei Tang, and Thai H. Ho
Subjects: Medicine, Science
Abstract: Abstract Renal Cell Carcinoma (RCC) is a fatal urological cancer, with one third of patients diagnosed with metastasis, resulting in a 5-year survival of only 12%. Recent advancements in therapies have increased survival in mRCC, but lack efficacy in subtypes, due to treatment resistance and toxic side effects. Currently, white blood cells, hemoglobin, and platelets are limitedly used as blood based biomarkers to help determine RCC prognosis. Cancer associated macrophage-like cells (CAMLs) are a potential mRCC biomarker which have been identified in peripheral blood of patients with malignant tumors and have been shown to predict poor clinical patient outcomes based on their number and size. In this study, blood samples from 40 RCC patients were obtained to evaluate the clinical utility of CAMLs. CAML changes were monitored during treatment regimens to evaluate their ability to predict treatment efficacy. It was observed that patients with smaller CAMLs had better progression free survival (HR = 2.84, 95% CI 1.22–6.60, p = 0.0273) and overall survival (HR = 3.95, 95% CI 1.45–10.78, p = 0.0154) versus patients with larger CAMLs. These findings suggest that CAMLs can be used as a diagnostic, prognostic, and predictive biomarker for patients with RCC which may help improve management of advanced RCC.
Published: 2023
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4. Extensive intratumor regional epigenetic heterogeneity in clear cell renal cell carcinoma targets kidney enhancers and is associated with poor outcome

Author: Louis Y. El Khoury, Xiaoyu Pan, Ryan A. Hlady, Ryan T. Wagner, Shafiq Shaikh, Liguo Wang, Mitchell R. Humphreys, Erik P. Castle, Melissa L. Stanton, Thai H. Ho, and Keith D. Robertson
Subjects: Clear cell renal cell cancer, Intra-tumor heterogeneity, DNA methylation, 5mC, Epigenomics, CNV, Medicine, Genetics, QH426-470
Abstract: Abstract Background Clear cell renal cell cancer (ccRCC), the 8th leading cause of cancer-related death in the US, is challenging to treat due to high level intratumoral heterogeneity (ITH) and the paucity of druggable driver mutations. CcRCC is unusual for its high frequency of epigenetic regulator mutations, such as the SETD2 histone H3 lysine 36 trimethylase (H3K36me3), and low frequency of traditional cancer driver mutations. In this work, we examined epigenetic level ITH and defined its relationships with pathologic features, aspects of tumor biology, and SETD2 mutations. Results A multi-region sampling approach coupled with EPIC DNA methylation arrays was conducted on a cohort of normal kidney and ccRCC. ITH was assessed using DNA methylation (5mC) and CNV-based entropy and Euclidian distances. We found elevated 5mC heterogeneity and entropy in ccRCC relative to normal kidney. Variable CpGs are highly enriched in enhancer regions. Using intra-class correlation coefficient analysis, we identified CpGs that segregate tumor regions according to clinical phenotypes related to tumor aggressiveness. SETD2 wild-type tumors overall possess greater 5mC and copy number ITH than SETD2 mutant tumor regions, suggesting SETD2 loss contributes to a distinct epigenome. Finally, coupling our regional data with TCGA, we identified a 5mC signature that links regions within a primary tumor with metastatic potential. Conclusion Taken together, our results reveal marked levels of epigenetic ITH in ccRCC that are linked to clinically relevant tumor phenotypes and could translate into novel epigenetic biomarkers.
Published: 2023
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5. MTAP deficiency creates an exploitable target for antifolate therapy in 9p21-loss cancers

Author: Omar Alhalabi, Jianfeng Chen, Yuxue Zhang, Yang Lu, Qi Wang, Sumankalai Ramachandran, Rebecca Slack Tidwell, Guangchun Han, Xinmiao Yan, Jieru Meng, Ruiping Wang, Anh G. Hoang, Wei-Lien Wang, Jian Song, Lidia Lopez, Alex Andreev-Drakhlin, Arlene Siefker-Radtke, Xinqiao Zhang, William F. Benedict, Amishi Y. Shah, Jennifer Wang, Pavlos Msaouel, Miao Zhang, Charles C. Guo, Bogdan Czerniak, Carmen Behrens, Luisa Soto, Vassiliki Papadimitrakopoulou, Jeff Lewis, Waree Rinsurongkawong, Vadeerat Rinsurongkawong, Jack Lee, Jack Roth, Stephen Swisher, Ignacio Wistuba, John Heymach, Jing Wang, Matthew T. Campbell, Eleni Efstathiou, Mark Titus, Christopher J. Logothetis, Thai H. Ho, Jianjun Zhang, Linghua Wang, and Jianjun Gao
Subjects: Science
Abstract: The deficiency of MTAP, an enzyme of the adenine salvage pathway, occurs in some cancers. Here the authors perform a small cohort phase II clinical trial with metastatic MTAP-deficient urothelial cancer (UC) and show an increased overall response when comparing to MTAP-proficient UC patients.
Published: 2022
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6. Phase Ib Study of Atezolizumab Plus Interferon-α with or without Bevacizumab in Patients with Metastatic Renal Cell Carcinoma and Other Solid Tumors

Author: Christian U. Blank, Deborah J. Wong, Thai H. Ho, Todd M. Bauer, Carrie B. Lee, Fabiola Bene-Tchaleu, Jing Zhu, Xiaosong Zhang, Edward Cha, and Mario Sznol
Subjects: atezolizumab, bevacizumab, checkpoint inhibition, interferon alfa, renal cell carcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: This Phase Ib study combined programmed death-ligand 1 inhibitor, atezolizumab, with other immunomodulatory agents in locally advanced and metastatic solid tumors. Arms B-D evaluated atezolizumab plus interferon-α, with/without vascular endothelial growth factor inhibitor, bevacizumab, in renal cell carcinoma (RCC) and other solid tumors. Arm B predominantly recruited patients with previously treated RCC or melanoma to receive atezolizumab plus interferon α-2b. Arm C investigated atezolizumab plus polyethylene glycol (PEG)-interferon α-2a in previously treated RCC. Arm D evaluated atezolizumab plus PEG-interferon α-2a and bevacizumab. Primary objectives were safety and tolerability; secondary objectives included clinical activity. Combination therapy was well tolerated, with safety profiles consistent with known risks of individual agents. The most frequent treatment-related toxicities were fatigue, chills, and pyrexia. The objective response rate (ORR) in arm B was 20.0% overall and 17.8% in patients with previously treated checkpoint inhibitor–naive RCC (n = 45). No responses were reported in arm C. The highest ORR in arm D was 46.7% in patients with treatment-naive RCC (n = 15). Data showed preliminary clinical activity and acceptable tolerability of atezolizumab plus interferon α-2b in patients with previously treated checkpoint inhibitor–naive RCC and of atezolizumab plus PEG-interferon α-2a and bevacizumab in patients with treatment-naive RCC.
Published: 2021
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7. The oscillatory solutions of multi-order fractional differential equations

Author: Thai, H. D. and Tuan, H. T.
Subjects: Mathematics - Dynamical Systems, 26A33, 34A08, 34C10, 34D05, 45A05, 45G05
Abstract: This paper systematically treats the asymptotic behavior of many (linear/nonlinear) classes of higher-order fractional differential equations with multiple terms. To do this, we utilize the characteristics of Caputo fractional differentiable functions, the comparison principle, counterfactual reasoning, and the spectral analysis method (concerning the integral presentations of basic solutions). Some numerical examples are also provided to demonstrate the validity of the proposed results.
Published: 2024

8. Unraveling the hierarchical genetic structure of tea green leafhopper, Matsumurasca onukii, in East Asia based on SSRs and SNPs

Author: Li Zhang, Christopher H. Dietrich, Ye Xu, Zhaofu Yang, Maohua Chen, Thai H. Pham, Cuong C. V. Le, Li Qiao, Masaya Matsumura, and Daozheng Qin
Subjects: Matsumurasca onukii, reduced‐representation genome sequencing, SNPs, SSRs, subtle genetic differentiation, tea pest, Ecology, QH540-549.5
Abstract: Abstract Matsumurasca onukii (Matsuda, R. (1952). Oyo‐Kontyu Tokyo, 8(1): 19–21), one of the dominant pests in major tea production areas in Asia, currently is known to occur in Japan, Vietnam, and China, and severely threatens tea production, quality, and international trade. To elucidate the population genetic structure of this species, 1633 single nucleotide polymorphisms (SNPs) and 18 microsatellite markers (SSRs) were used to genotype samples from 27 sites representing 18 geographical populations distributed throughout the known range of the species in East Asia. Analyses of both SNPs and SSRs showed that M. onukii populations in Yunnan exhibit high‐genetic differentiation and structure compared with the other populations. The Kagoshima (JJ) and Shizuoka (JS) populations from Japan were separated from populations from China by SNPs, but clustered with populations from Jinhua (JH), Yingde (YD), Guilin (GL), Fuzhou (FZ), Hainan (HQ), Leshan (CT), Chongqing (CY), and Zunyi (ZY) tea plantations in China and the Vietnamese Vinh Phuc (VN) population based on the SSR data. In contrast, CT, CY, ZY, and Shaanxi (SX) populations clustered together based on SNPs, but were separated by SSRs. Both marker datasets identified significant geographic differentiation among the 18 populations. Various environmental and anthropogenic factors, including geographical barriers to migration, human transport of hosts (Camellia sinesis [L.] O. Kuntze) and adaptation of M. onukii to various local climatic zones possibly account for the rapid spread of this pest in Asia. The results demonstrate that SNPs from high‐throughput genotyping data can be used to reveal subtle genetic substructure at broad scales in r‐strategist insects.
Published: 2022
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9. Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma

Author: Ziad Bakouny, David A. Braun, Sachet A. Shukla, Wenting Pan, Xin Gao, Yue Hou, Abdallah Flaifel, Stephen Tang, Alice Bosma-Moody, Meng Xiao He, Natalie Vokes, Jackson Nyman, Wanling Xie, Amin H. Nassar, Sarah Abou Alaiwi, Ronan Flippot, Gabrielle Bouchard, John A. Steinharter, Pier Vitale Nuzzo, Miriam Ficial, Miriam Sant’Angelo, Juliet Forman, Jacob E. Berchuck, Shaan Dudani, Kevin Bi, Jihye Park, Sabrina Camp, Maura Sticco-Ivins, Laure Hirsch, Sylvan C. Baca, Megan Wind-Rotolo, Petra Ross-Macdonald, Maxine Sun, Gwo-Shu Mary Lee, Steven L. Chang, Xiao X. Wei, Bradley A. McGregor, Lauren C. Harshman, Giannicola Genovese, Leigh Ellis, Mark Pomerantz, Michelle S. Hirsch, Matthew L. Freedman, Michael B. Atkins, Catherine J. Wu, Thai H. Ho, W. Marston Linehan, David F. McDermott, Daniel Y. C. Heng, Srinivas R. Viswanathan, Sabina Signoretti, Eliezer M. Van Allen, and Toni K. Choueiri
Subjects: Science
Abstract: Sarcomatoid and rhabdoid tumours are highly aggressive forms of renal cell carcinoma that are also responsive to immunotherapy. In this study, the authors perform a comprehensive molecular characterization of these tumours discovering an enrichment of specific alterations and an inflamed phenotype.
Published: 2021
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10. Classification of Vascular Plants in Vietnam According to Modern Classification Systems

Author: Ngoc A. Luu-dam, Ngan T. Lu, Thai H. Pham, and Truong V. Do
Subjects: angiosperms, APG IV, classification, gymnosperms, lycophytes and ferns, PPG1, Botany, QK1-989
Abstract: Vietnam is extremely rich in biodiversity, with a remarkable range of habitats and more than 13,500 species of vascular plants recorded for the flora of Vietnam. This number represents about 3 to 5% of the world’s diversity of vascular plants. Over the past 30 years, there were two important documents on the vascular plants of Vietnam published, An Illustrated Flora of Vietnam (IFV) and Checklist of Plant Species of Vietnam (CPSV). During the past half century, the advent of molecular phylogenetics has witnessed dramatic changes in the classifications of vascular plants, and some modern classification systems of vascular plants have been established, e.g., PPG I, GPG, and APG. However, the vascular plants of Vietnam have not yet been classified according to these modern classification systems. In this paper, we present the history of the classification of vascular plants in Vietnam, compare the circumscription of all families of vascular plants occurring within Vietnam in IFV, CPSV, and the modern classification systems when applicable, and summarize familial assignments of all controversial genera in the different classifications. Furthermore, we also arrange the 37 families of lycophytes and ferns occurring within Vietnam according to the latest classification system (PPG I) and the 8 families of gymnosperms according to the latest Christenhusz’s system (GPG). The 246 families of angiosperms are arranged according to the fourth edition of the latest Angiosperm Phylogeny Group (APG IV). These results are the foundation stones and would be helpful for future research on the flora of Vietnam and the arrangement of plant collections in Vietnamese herbaria based on the updated classifications.
Published: 2023
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11. 8q24 clear cell renal cell carcinoma germline variant is associated with VHL mutation status and clinical aggressiveness

Author: Jeanette E. Eckel-Passow, Huihuang Yan, Matthew L. Kosel, Daniel Serie, Paul A. Decker, Robert B. Jenkins, Brian Costello, Bradley Leibovich, Thai H. Ho, and Alexander Parker
Subjects: Kidney, GWAS, Subtype, Hi-C, Diseases of the genitourinary system. Urology, RC870-923
Abstract: Abstract Background The four most commonly-mutated genes in clear cell renal cell carcinoma (ccRCC) tumors are BAP1, PBRM1, SETD2 and VHL. And, there are currently 14 known RCC germline variants that have been reproducibly shown to be associated with RCC risk. However, the association of germline genetics with tumor genetics and clinical aggressiveness are unknown. Methods We analyzed 420 ccRCC patients from The Cancer Genome Atlas. Molecular subtype was determined based on acquired mutations in BAP1, PBRM1, SETD2 and VHL. Aggressive subtype was defined clinically using Mayo SSIGN score and molecularly using the ccA/ccB gene expression subtype. Publically-available Hi-C data were used to link germline risk variants with candidate target genes. Results The 8q24 variant rs35252396 was significantly associated with VHL mutation status (OR = 1.6, p = 0.0037) and SSIGN score (OR = 1.9, p = 0.00094), after adjusting for multiple comparisons. We observed that, while some germline variants have interactions with nearby genes, some variants demonstrate long-range interactions with target genes. Conclusions These data further demonstrate the link between rs35252396, HIF pathway and ccRCC clinical aggressiveness, providing a more comprehensive picture of how germline genetics and tumor genetics interact with respect to tumor development and progression.
Published: 2020
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12. Concordance of PD‐1 and PD‐L1 (B7‐H1) in paired primary and metastatic clear cell renal cell carcinoma

Author: Jeanette E. Eckel‐Passow, Thai H. Ho, Daniel J. Serie, John C. Cheville, R. Houston Thompson, Brian A. Costello, Haidong Dong, Eugene D. Kwon, Bradley C. Leibovich, and Alexander S. Parker
Subjects: B7-H1, ccRCC, PD-1, PD-L1, RCC, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Abstract Objectives Previous studies noted discordance of programmed death‐1 (PD‐1) and one of its ligands (PD‐L1) across patient‐matched primary and metastatic clear cell renal cell carcinoma (ccRCC). There are inconsistencies if the primary or metastatic tumor has higher expression, and whether metastatic tumor expression is associated with patient outcome. Thus, we examined PD‐1 and PD‐L1 in patient‐matched tumors using a large number of ccRCC patients with long follow‐up. Materials and Methods We analyzed PD‐1 and PD‐L1 using immunohistochemistry in patient‐matched primary and metastatic tumors from 110 ccRCC patients. Concordance was assessed among longitudinal metastatic tumors, as well as across patient‐matched primary and metastatic tumors. Cox proportional hazards regression was used to evaluate the associations of metastatic tumor expression with cancer‐specific survival. Results We observed inter‐metastatic tumor heterogeneity of PD‐1 in 25 (69%) of the 36 patients and of PD‐L1 in seven (19%) patients. Concordance between patient‐matched primary and metastatic tumors was 73% (Kappa = 0.16, 95% CI: −0.003‐0.32). Similarly, concordance of PD‐L1 between metastatic and patient‐matched primary tumors was 78% (Kappa = 0.27, 95% CI: 0.09‐0.46). Both markers demonstrated higher expression in primary vs metastatic tumors. Metastatic tumor expression of PD‐1 was significantly associated with metastatic location (P
Published: 2020
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13. In silico DNA methylation analysis identifies potential prognostic biomarkers in type 2 papillary renal cell carcinoma

Author: Man Yang, Ryan A. Hlady, Dan Zhou, Thai H. Ho, and Keith D. Robertson
Subjects: biomarkers, epigenetics, epigenomics, gene copy number, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Abstract There are currently no effective treatments for advanced‐stage papillary renal cell carcinoma (PRCC). The goal of this study is to define potential DNA methylation‐based markers and treatment targets for advanced‐stage type 2 PRCC. Progressive DNA methylation changes and copy number variation (CNV) from localized to advanced‐stage type 2 PRCC are analyzed by using methylation data generated by TCGA's kidney renal papillary cell carcinoma (TCGA‐KIRP, 450k array) project. Survival analyses are performed for the identified biomarkers and genes with CNV. In addition, expression of the corresponding genes is investigated by RNA‐seq analysis. Progressive methylation changes in several CpGs from localized to advanced‐stage type 2 PRCC are observed. Four CpGs (cg00489401, cg27649239, cg20555674, and cg07196505) in particular are identified as markers for differentiating between localized and advanced‐stage type 2 PRCC. Copy number analysis reveals that copy gain of PTK7 mostly occurs in advanced‐stage type 2 PRCC. Both the four CpG methylation changes and PTK7 copy number gain are associated with patient survival. RNA‐seq analysis demonstrates that PTK7 copy gain leads to higher PTK7 expression relative to tumors without copy number gain. Moreover, PTK7 is significantly upregulated from localized to advanced‐stage type 2 PRCC and is linked to cancer cell invasion. In conclusion, DNA methylation markers that differentiate between localized and advanced‐stage type 2 PRCC may serve as useful markers for disease staging or outcome, while PTK7 copy gain represents a potential treatment target for advanced‐stage type 2 PRCC. Stepwise methylation changes and copy number gain also associate with disease stage in PRCC patients.
Published: 2019
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14. The Associations of Suspected COVID-19 Symptoms with Anxiety and Depression as Modified by Hemodialysis Dietary Knowledge: A Multi-Dialysis Center Study

Author: Loan T. Dang, Thuc C. Luong, Dung H. Nguyen, Trung A. Hoang, Hoai T. Nguyen, Hoang C. Nguyen, Thai H. Duong, Tu T. Tran, Linh V. Pham, Tuan V. Ngo, Hoi T. Nguyen, Nga T. Trieu, Thinh V. Do, Manh V. Trinh, Tung H. Ha, Dung T. Phan, Binh N. Do, Shwu-Huey Yang, Tsae-Jyy Wang, and Tuyen Van Duong
Subjects: hemodialysis, psychometric properties, anxiety, depression, suspected COVID-19 symptoms, health literacy, Nutrition. Foods and food supply, TX341-641
Abstract: During the COVID-19 pandemic, it is essential to evaluate hemodialysis patients’ dietary knowledge, especially among those with COVID-19 related symptoms, in order to identify appropriate strategies in managing their mental health. The study’s purposes were to test the psychometric properties of the hemodialysis dietary knowledge (HDK) scale, and to investigate the modifying impact of HDK on the associations of suspected COVID-19 symptoms (S-COVID-19-S) with anxiety and depression among hemodialysis patients. A cross-sectional study was conducted from July 2020 to March 2021 at eight hospitals across Vietnam. Data of 875 hemodialysis patients were analyzed, including socio-demographic, anxiety (the generalized anxiety disorder scale, GAD-7), depression (the patient health questionnaire, PHQ-9), S-COVID-19-S, HDK, health literacy, and digital healthy diet literacy. Confirmatory factor analysis (CFA) and logistic regression models were used to analyze the data. The HDK scale demonstrates the satisfactory construct validity with good model fit (Goodness of Fit Index, GFI = 0.96; Adjusted Goodness of Fit Index, AGFI = 0.90; Standardized Root Mean Square Residual, SRMR = 0.05; Root Mean Square Error of Approximation, RMSEA = 0.09; Normed Fit Index, NFI = 0.96; Comparative Fit Index, CFI = 0.96, and Parsimony goodness of Fit Index, PGFI = 0.43), criterion validity (as correlated with HL (r = 0.22, p < 0.01) and DDL (r = 0.19, p < 0.01), and reliability (Cronbach alpha = 0.70)). In the multivariate analysis, S-COVID-19-S was associated with a higher likelihood of anxiety (odds ratio, OR, 20.76; 95% confidence interval, 95%CI, 8.85, 48.70; p < 0.001) and depression (OR, 12.95; 95%CI, 6.67, 25.14, p < 0.001). A higher HDK score was associated with a lower likelihood of anxiety (OR, 0.70; 95%CI, 0.64, 0.77; p < 0.001) and depression (OR, 0.72; 95%CI, 0.66, 0.79; p < 0.001). In the interaction analysis, the negative impacts of S-COVID-19-S on anxiety and depression were mitigated by higher HDK scores (p < 0.001). In conclusion, HDK is a valid and reliable tool to measure dietary knowledge in hemodialysis patients. Higher HDK scores potentially protect patients with S-COVID-19-S from anxiety and depression during the pandemic.
Published: 2022
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15. Impacts and interactions of COVID-19 response involvement, health-related behaviours, health literacy on anxiety, depression and health-related quality of life among healthcare workers: a cross-sectional study

Author: Kien Trung Nguyen, Tuyen Van Duong, Tien V Tran, Hoang C Nguyen, Linh V Pham, Minh H Nguyen, Huu Cong Nguyen, Tung H Ha, Dung T Phan, Hung K Dao, Phuoc B Nguyen, Manh V Trinh, Thinh V Do, Hung Q Nguyen, Thao T P Nguyen, Nhan P T Nguyen, Cuong Q Tran, Khanh V Tran, Trang T Duong, Hai X Pham, Lam V Nguyen, Tam T Vo, Binh N Do, Thai H Duong, Minh Khue Pham, Thu T M Pham, Shwu-Huey Yang, and Jane C J Chao
Subjects: Medicine
Abstract: Objectives We examined impacts and interactions of COVID-19 response involvement, health-related behaviours and health literacy (HL) on anxiety, depression, and health-related quality of life (HRQoL) among healthcare workers (HCWs).Design A cross-sectional study was conducted. Data were collected 6 April to 19 April 2020 using online-based, self-administered questionnaires.Setting 19 hospitals and health centres in Vietnam.Participants 7 124 HCWs aged 21–60 years.Results The COVID-19 response-involved HCWs had higher anxiety likelihood (OR (95% CI)=4.41 (3.53 to 5.51)), higher depression likelihood (OR(95% CI)=3.31 (2.71 to 4.05)) and lower HRQoL score (coefficient, b(95% CI)=−2.14 (−2.89 to −1.38)), compared with uninvolved HCWs. Overall, HCWs who smoked or drank at unchanged/increased levels had higher likelihood of anxiety, depression and lower HRQoL scores; those with unchanged/healthier eating, unchanged/more physical activity and higher HL scores had lower likelihood of anxiety, depression and higher HRQoL scores. In comparison to uninvolved HCWs who smoked or drank at never/stopped/reduced levels, involved HCWs with unchanged/increased smoking or drinking had lower anxiety likelihood (OR(95% CI)=0.34 (0.14 to 0.83)) or (OR(95% CI)=0.26 (0.11 to 0.60)), and lower depression likelihood (OR(95% CI)=0.33 (0.15 to 0.74)) or (OR(95% CI)=0.24 (0.11 to 0.53)), respectively. In comparison with uninvolved HCWs who exercised at never/stopped/reduced levels, or with those in the lowest HL quartile, involved HCWs with unchanged/increased exercise or with one-quartile HL increment reported lower anxiety likelihood (OR(95% CI)=0.50 (0.31 to 0.81)) or (OR(95% CI)=0.57 (0.45 to 0.71)), lower depression likelihood (OR(95% CI)=0.40 (0.27 to 0.61)) or (OR(95% CI)=0.63 (0.52 to 0.76)), and higher HRQoL scores (b(95% CI)=2.08 (0.58 to 3.58)), or (b(95% CI)=1.10 (0.42 to 1.78)), respectively.Conclusions Physical activity and higher HL were found to protect against anxiety and depression and were associated with higher HRQoL. Unexpectedly, smoking and drinking were also found to be coping behaviours. It is important to have strategic approaches that protect HCWs’ mental health and HRQoL.
Published: 2020
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16. Determinants of Health Literacy and Its Associations With Health-Related Behaviors, Depression Among the Older People With and Without Suspected COVID-19 Symptoms: A Multi-Institutional Study

Author: Binh N. Do, Phung-Anh Nguyen, Khue M. Pham, Hoang C. Nguyen, Minh H. Nguyen, Cuong Q. Tran, Thao T. P. Nguyen, Tien V. Tran, Linh V. Pham, Khanh V. Tran, Trang T. Duong, Thai H. Duong, Kien T. Nguyen, Thu T. M. Pham, Min-Huei Hsu, and Tuyen Van Duong
Subjects: COVID-19, older people, health literacy, health-related behaviors, depression, Vietnam, Public aspects of medicine, RA1-1270
Abstract: Purpose: We examined factors associated with health literacy among elders with and without suspected COVID-19 symptoms (S-COVID-19-S).Methods: A cross-sectional study was conducted at outpatient departments of nine hospitals and health centers 14 February−2 March 2020. Self-administered questionnaires were used to assess patient characteristics, health literacy, clinical information, health-related behaviors, and depression. A sample of 928 participants aged 60–85 years were analyzed.Results: The proportion of people with S-COVID-19-S and depression were 48.3 and 13.4%, respectively. The determinants of health literacy in groups with and without S-COVID-19-S were age, gender, education, ability to pay for medication, and social status. In people with S-COVID-19-S, one-score increment of health literacy was associated with 8% higher healthy eating likelihood (odds ratio, OR, 1.08; 95% confidence interval, 95%CI, 1.04, 1.13; p < 0.001), 4% higher physical activity likelihood (OR, 1.04; 95%CI, 1.01, 1.08, p = 0.023), and 9% lower depression likelihood (OR, 0.90; 95%CI, 0.87, 0.94; p < 0.001). These associations were not found in people without S-COVID-19-S.Conclusions: The older people with higher health literacy were less likely to have depression and had healthier behaviors in the group with S-COVD-19-S. Potential health literacy interventions are suggested to promote healthy behaviors and improve mental health outcomes to lessen the pandemic's damage in this age group.
Published: 2020
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17. Healthy Dietary Intake Behavior Potentially Modifies the Negative Effect of COVID-19 Lockdown on Depression: A Hospital and Health Center Survey

Author: Khue M. Pham, Linh V. Pham, Dung T. Phan, Tien V. Tran, Hoang C. Nguyen, Minh H. Nguyen, Huu C. Nguyen, Tung H. Ha, Hung K. Dao, Phuoc B. Nguyen, Manh V. Trinh, Thinh V. Do, Hung Q. Nguyen, Thao T. P. Nguyen, Nhan P. T. Nguyen, Cuong Q. Tran, Khanh V. Tran, Trang T. Duong, Lam V. Nguyen, Thao T. Do, Tam T. Vo, Binh N. Do, Thai H. Duong, Thu T. M. Pham, Thuy T. Le, Ngoc T. Do, Hoai T. T. Nguyen, Thuy T. T. Mai, Dung T. Ha, Huong T. M. Ngo, Kien T. Nguyen, Shwu-Huey Yang, Jane C.-J. Chao, and Tuyen Van Duong
Subjects: COVID-19, coronavirus, lockdown, healthy eating, psychological, physical activity, Nutrition. Foods and food supply, TX341-641
Abstract: Background: The COVID-19 pandemic causes a huge burden for affected countries. Several public health interventions were applied to contain the infection. However, the pandemic itself and the lockdown measure negatively influence people's lifestyles and psychological health.Purpose: To explore determinants of healthy dietary intake and depression, and examine the interaction between healthy dietary intake and COVID-19 lockdown on depression.Methods: A cross-sectional study was conducted at 18 hospitals and health centers from February 14 to May 31, 2020. Data of 8,291 outpatients were collected including patients' characteristics, clinical parameters, health literacy, healthy dietary intake (using the healthy eating score, HES), other health-related behaviors, and depression (using the patient health questionnaire, PHQ). Depression was defined as PHQ score ≥ 10.Results: Protective factors of healthy dietary intake and depression were higher education, better medication payment ability, higher social status, more physical activity, and higher health literacy, whereas older age, ever married, own business or other types of occupation, lockdown, suspected COVID-19 symptoms, and comorbidity were associated with lower HES scores and a higher depression likelihood. Besides, overweight/obesity and alcohol drinking were associated with lower HES scores. As compared with patients not under lockdown and with lowest HES score, those who were under lockdown and with lowest HES score had 10.6 times higher depression likelihood (odds ratio, OR, 10.60; 95% CI 6.88, 16.32; p < 0.001), whereas people with higher HES score had 15% lower depression likelihood (OR 0.85; 95% CI 0.82, 0.89; p < 0.001).Conclusions: Healthy dietary intake and depression were determined by several sociodemographic, clinical, and behavioral factors. Lockdown measure affects people's dietary intake behavior and depression. Importantly, healthy dietary intake potentially modifies the negative effect of lockdown on depression.
Published: 2020
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18. Lgr5-positive endothelial progenitor cells occupy a tumor and injury prone niche in the kidney vasa recta

Author: Mike R. Wilson, Jeanne Holladay, Rachael Sheridan, Galen Hostetter, Bree Berghuis, Carrie Graveel, Curt Essenburg, Anderson Peck, Thai H. Ho, Melissa Stanton, and Ronald L. Chandler
Subjects: Vasa recta, Stem cells, Acute kidney injury, Ischemia, Biology (General), QH301-705.5
Abstract: The Wnt pathway co-receptor, Leucine Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5), labels tumor-prone stem cell populations in certain types of tissue. In this study, we show that ARID1A and PIK3CA mutations in LGR5+ cells result in renal angiosarcomas in adult mice. The tumors originate in the renal medulla. We further show that LGR5 labels SOX17+/CD31+/CD34+/CD133+/AQP1+/CD146+ endothelial progenitor cells within the descending vasa recta or straight arterioles of the kidney, which are specialized capillaries that maintain medullary osmotic gradients necessary for water reabsorption and the production of concentrated urine. LGR5+ endothelial progenitor cells are tightly associated with contractile pericytes within the descending vasa recta. Long-term in vivo lineage tracing revealed that LGR5+ cells give rise to renal medullary vasculature. We further show that LGR5+ cells are activated in response to ischemic kidney injury. Our findings uncover a physiologically relevant endothelial progenitor cell population within the kidney vasa recta.
Published: 2020
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19. Pazopanib for renal cell carcinoma leads to elevated mean arterial pressures in a murine model

Author: Amber Kempton, Cody Justice, Aaron Guo, Matthew Cefalu, Michael Makara, Paul Janssen, Thai H Ho, and Sakima A Smith
Subjects: renal cell carcinoma, hypertension, pazopanib, tyrosine kinase inhibitors, cardio-oncology, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Background: In the setting of metastatic RCC (mRCC), pazopanib is approved as first line therapy. Unfortunately treatment may lead to cardiotoxicity such as hypertension, heart failure, and myocardial ischemia. Objective: Define the in vivo role of pazopanib in the development of cardiotoxicity. Methods: Wild type mice were dosed for 42 days via oral gavage, and separated into control and treatment (pazopanib) groups. Baseline ECG’s, echocardiograms, and blood pressures were recorded. At the conclusion of the study functional parameters were again recorded, and animals were used for pathological, histological, and protein analysis. Results: After 2 weeks of dosing with pazopanib, the treatment group exhibited a statistically significant increase in mean arterial pressure compared to control mice (119 ± 11.7 mmHg versus 108 ± 8.2 mmHg, p = 0.049). Treatment with pazopanib led to a significant reduction in the cardiac output of mice. Conclusion: Our findings in mice clearly demonstrate that treatment with pazopanib leads to a significant elevation in blood pressure after 2 weeks of dosing and this persists for the duration of dosing. The continued development of the cardio-oncology field will be paramount in providing optimal oncologic care while simultaneously improving cardiac outcomes through further investigation into the mechanisms of CV toxicity.
Published: 2018
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20. The involvement of 4‐1BB/4‐1BBL signaling in glial cell‐mediated hypothalamic inflammation in obesity

Author: Jiye Kim, Yoon‐Hee Kwon, Chu‐Sook Kim, Thai H. Tu, Byung‐Sam Kim, Yeonsoo Joe, Hun T. Chung, Tsuyoshi Goto, Teruo Kawada, Taesun Park, Myung‐Sook Choi, Min‐Seon Kim, and Rina Yu
Subjects: hypothalamus, inflammation, obesity, Biology (General), QH301-705.5
Abstract: Obesity‐induced inflammation occurs not only in peripheral tissues but also in areas of the central nervous system. Glial cells such as astrocytes and microglia play crucial roles in obesity‐related hypothalamic inflammation, leading to the derangement of energy metabolism and neurodegenerative pathologies. Here, we show that the interaction of 4‐1BB/4‐1BBL between lipid‐laden astrocytes/microglia promotes hypothalamic inflammation in obesity. Stimulation of 4‐1BB, a member of the TNF receptor superfamily, and/or its ligand 4‐1BBL on astrocytes and/or microglia with a specific agonist resulted in activation of the inflammatory signaling pathway and enhanced production of inflammatory mediators. Contact coculture of lipid‐laden astrocytes and microglia increased the production of inflammatory mediators, and blockade of the 4‐1BB/4‐1BBL interaction reduced the inflammatory response. Moreover, deficiency of 4‐1BB reduced hypothalamic inflammation in obese mice fed an high‐fat diet. These findings suggest that 4‐1BBL/4‐1BB signaling enhances the glial cell‐mediated inflammatory cross talk and participates in obesity‐induced hypothalamic inflammation.
Published: 2018
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21. Columnar-Lined Esophagus Develops via Wound Repair in a Surgical Model of Reflux EsophagitisSummary

Author: Agoston T. Agoston, Thai H. Pham, Robert D. Odze, David H. Wang, Kiron M. Das, Stuart J. Spechler, and Rhonda F. Souza
Subjects: Diseases of the digestive system. Gastroenterology, RC799-869
Abstract: Background & Aims: After esophagojejunostomy, rodents develop reflux esophagitis and a columnar-lined esophagus with features of Barrett’s metaplasia. This rodent columnar-lined esophagus has been proposed to develop from cellular reprogramming of progenitor cells, but studies on early columnar-lined esophagus development are lacking. We performed a systematic, histologic, and immunophenotypic analysis of columnar-lined esophagus development in rats after esophagojejunostomy. Methods: At various times after esophagojejunostomy in 52 rats, the esophagus was removed and tissue sections were evaluated for type, location, and length of columnar lining. Molecular characteristics were evaluated by immunohistochemistry and immunofluorescence. Results: At week 2, ulceration was seen in esophageal squamous epithelium, starting distally at the esophagojejunostomy anastomosis. Re-epithelialization of the distal ulcer segment occurred via proliferation and expansion of immature-appearing glands budding directly off jejunal crypts, characteristic of wound healing. The columnar-lined esophagus's immunoprofile was similar to jejunal crypt epithelium, and columnar-lined esophagus length increased significantly from 0.15 mm (±0.1 SEM) at 2 weeks to 5.22 mm (±0.37) at 32 weeks. Neoglands were found within esophageal ulcer beds, and spindle-shaped cells expressing epithelial-mesenchymal transition markers were found at the columnar-lined esophagus's leading edge. Only proliferative squamous epithelium was found at the proximal ulcer border. Conclusions: After esophagojejunostomy in rats, metaplastic columnar-lined esophagus develops via a wound healing process that does not appear to involve cellular reprogramming of progenitor cells. This process involves EMT-associated migration of jejunal cells into the esophagus, where they likely have a competitive advantage over squamous cells in the setting of ongoing gastroesophageal reflux disease. Keywords: Gastroesophageal Reflux, Barrett’s Esophagus, Epithelial-Mesenchymal Transition
Published: 2018
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22. Single and Combinative Impacts of Healthy Eating Behavior and Physical Activity on COVID-19-like Symptoms among Outpatients: A Multi-Hospital and Health Center Survey

Author: Minh H. Nguyen, Thu T. M. Pham, Dinh N. Vu, Binh N. Do, Hoang C. Nguyen, Thai H. Duong, Khue M. Pham, Linh V. Pham, Thao T. P. Nguyen, Cuong Q. Tran, Quyen H. Nguyen, Thanh M. Hoang, Khanh V. Tran, Trang T. Duong, Shwu-Huey Yang, Chyi-Huey Bai, and Tuyen Van Duong
Subjects: COVID-19-like symptoms, healthy eating score, fruits, vegetables, fish, physical activity, Nutrition. Foods and food supply, TX341-641
Abstract: Background: Healthy eating and physical activity are effective non-pharmacological approaches to boost immune function and contain the pandemic. We aimed to explore the associations and interactions between physical activity and healthy eating behavior with COVID-19-like symptoms (Slike-CV19S). Methods: A cross-sectional study was conducted on 3947 outpatients, from 14 February to 2 March 2020, at nine health facilities in Vietnam. Data collection included sociodemographic characteristics, healthy eating behavior (using the healthy eating score (HES) questionnaire), physical activity (using the short form international physical activity questionnaire), and Slike-CV19S. The associations and interactions were tested using logistic regression models. Results: Frequent intake of fruits (OR = 0.84; p = 0.016), vegetables (OR = 0.72; p = 0.036), and fish (OR = 0.43; p < 0.001) were associated with a lower Slike-CV19S likelihood, as compared with infrequent intake. Patients with higher HES levels (OR = 0.84; p = 0.033 for medium HES; OR = 0.77; p = 0.006 for high HES) or being physically active (OR = 0.69; p < 0.001) had a lower Slike-CV19S likelihood, as compared to those with low HES or physical inactivity, respectively. Patients with medium HES who were physically active (OR = 0.69; p = 0.005), or with high HES and physically active (OR = 0.58; p < 0.001), had a lower Slike-CV19S likelihood, as compared to those with low HES and physical inactivity. Conclusions: Healthy eating behavior and physical activity showed single and combinative impacts on protecting people from Slike-CV19S. Strategic approaches are encouraged to improve healthy behaviors, which may further contribute to containing the pandemic.
Published: 2021
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23. Clinical Implementation of Integrated Genomic Profiling in Patients with Advanced Cancers

Author: Mitesh J. Borad, Jan B. Egan, Rachel M. Condjella, Winnie S. Liang, Rafael Fonseca, Nicole R. Ritacca, Ann E. McCullough, Michael T. Barrett, Katherine S. Hunt, Mia D. Champion, Maitray D. Patel, Scott W. Young, Alvin C. Silva, Thai H. Ho, Thorvardur R. Halfdanarson, Robert R. McWilliams, Konstantinos N. Lazaridis, Ramesh K. Ramanathan, Angela Baker, Jessica Aldrich, Ahmet Kurdoglu, Tyler Izatt, Alexis Christoforides, Irene Cherni, Sara Nasser, Rebecca Reiman, Lori Cuyugan, Jacquelyn McDonald, Jonathan Adkins, Stephen D. Mastrian, Riccardo Valdez, Dawn E. Jaroszewski, Daniel D. Von Hoff, David W. Craig, A. Keith Stewart, John D. Carpten, and Alan H. Bryce
Subjects: Medicine, Science
Abstract: Abstract DNA focused panel sequencing has been rapidly adopted to assess therapeutic targets in advanced/refractory cancer. Integrated Genomic Profiling (IGP) utilising DNA/RNA with tumour/normal comparisons in a Clinical Laboratory Improvement Amendments (CLIA) compliant setting enables a single assay to provide: therapeutic target prioritisation, novel target discovery/application and comprehensive germline assessment. A prospective study in 35 advanced/refractory cancer patients was conducted using CLIA-compliant IGP. Feasibility was assessed by estimating time to results (TTR), prioritising/assigning putative therapeutic targets, assessing drug access, ascertaining germline alterations, and assessing patient preferences/perspectives on data use/reporting. Therapeutic targets were identified using biointelligence/pathway analyses and interpreted by a Genomic Tumour Board. Seventy-five percent of cases harboured 1–3 therapeutically targetable mutations/case (median 79 mutations of potential functional significance/case). Median time to CLIA-validated results was 116 days with CLIA-validation of targets achieved in 21/22 patients. IGP directed treatment was instituted in 13 patients utilising on/off label FDA approved drugs (n = 9), clinical trials (n = 3) and single patient IND (n = 1). Preliminary clinical efficacy was noted in five patients (two partial response, three stable disease). Although barriers to broader application exist, including the need for wider availability of therapies, IGP in a CLIA-framework is feasible and valuable in selection/prioritisation of anti-cancer therapeutic targets.
Published: 2016
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24. NOD-Like Receptor Protein 3 Inflammasome Priming and Activation in Barrettâs Epithelial CellsSummary

Author: Yuji Nadatani, Xiaofang Huo, Xi Zhang, Chunhua Yu, Edaire Cheng, Qiuyang Zhang, Kerry B. Dunbar, Arianne Theiss, Thai H. Pham, David H. Wang, Toshio Watanabe, Yasuhiro Fujiwara, Tetsuo Arakawa, Stuart J. Spechler, and Rhonda F. Souza
Subjects: Diseases of the digestive system. Gastroenterology, RC799-869
Abstract: Background & Aims: Microbial molecular products incite intestinal inflammation by activating Toll-like receptors (TLRs) and inflammasomes of the innate immune system. This systemâs contribution to esophageal inflammation is not known. Gram-negative bacteria, which dominate the esophageal microbiome in reflux esophagitis, produce lipopolysaccharide (LPS), a TLR4 ligand. TLR4 signaling produces pro-interleukin (IL)1Î², pro-IL18, and NOD-like receptor protein 3 (NLRP3), which prime the NLRP3 inflammasome. Subsequent NLRP3 inflammasome activation cleaves caspase-1, inducing secretion of proinflammatory cytokines and pyroptosis (inflammatory cell death). We explored LPS effects on NLRP3 inflammasome priming and activation in esophageal cells. Methods: We exposed esophageal squamous and Barrettâs epithelial cells to LPS and measured the following: (1) TLR4, pro-IL1Î², pro-IL18, and NLRP3 expression; (2) caspase-1 activity; (3) tumor necrosis factor-Î±, IL8, IL1Î², and IL18 secretion; (4) lactate dehydrogenase (LDH) release (a pyroptosis marker); and (5) mitochondrial reactive oxygen species (ROS). As inhibitors, we used acetyl-Tyr-Val-Ala-Asp-CHO for caspase-1, small interfering RNA for NLRP3, and (2-(2,2,6,6,-Tetramethylpiperidin-1-oxyl-4-ylamino)-2-oxoethyl)triphenylphosphonium chloride for mitochondrial ROS. Results: Squamous and Barrettâs cells expressed similar levels of TLR4, but LPS induced TLR4 signaling that increased tumor necrosis factor-Î± and IL8 secretion only in Barrettâs cells. Barrettâs cells treated with LPS showed increased expression of pro-IL18, pro-IL1Î², and NLRP3, and increased mitochondrial ROS levels, caspase-1 activity, IL1Î² and IL18 secretion, and LDH release. Acetyl-Tyr-Val-Ala-Asp-CHO, NLRP3 small interfering RNA, and Mito-TEMPO all blocked LPS-induced IL1Î² and IL18 secretion and LDH release. Conclusions: In Barrettâs cells, LPS both primes and activates the NLRP3 inflammasome, causing secretion of proinflammatory cytokines and pyroptosis. By triggering molecular events promoting inflammation, the esophageal microbiome might contribute to inflammation-mediated carcinogenesis in Barrettâs esophagus. Keywords: IL1Î², Pyroptosis, Esophageal Squamous Cell, GERD, Cytokine
Published: 2016
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25. Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma

Author: Fengju Chen, Yiqun Zhang, Yasin Şenbabaoğlu, Giovanni Ciriello, Lixing Yang, Ed Reznik, Brian Shuch, Goran Micevic, Guillermo De Velasco, Eve Shinbrot, Michael S. Noble, Yiling Lu, Kyle R. Covington, Liu Xi, Jennifer A. Drummond, Donna Muzny, Hyojin Kang, Junehawk Lee, Pheroze Tamboli, Victor Reuter, Carl Simon Shelley, Benny A. Kaipparettu, Donald P. Bottaro, Andrew K. Godwin, Richard A. Gibbs, Gad Getz, Raju Kucherlapati, Peter J. Park, Chris Sander, Elizabeth P. Henske, Jane H. Zhou, David J. Kwiatkowski, Thai H. Ho, Toni K. Choueiri, James J. Hsieh, Rehan Akbani, Gordon B. Mills, A. Ari Hakimi, David A. Wheeler, and Chad J. Creighton
Subjects: Biology (General), QH301-705.5
Abstract: On the basis of multidimensional and comprehensive molecular characterization (including DNA methalylation and copy number, RNA, and protein expression), we classified 894 renal cell carcinomas (RCCs) of various histologic types into nine major genomic subtypes. Site of origin within the nephron was one major determinant in the classification, reflecting differences among clear cell, chromophobe, and papillary RCC. Widespread molecular changes associated with TFE3 gene fusion or chromatin modifier genes were present within a specific subtype and spanned multiple subtypes. Differences in patient survival and in alteration of specific pathways (including hypoxia, metabolism, MAP kinase, NRF2-ARE, Hippo, immune checkpoint, and PI3K/AKT/mTOR) could further distinguish the subtypes. Immune checkpoint markers and molecular signatures of T cell infiltrates were both highest in the subtype associated with aggressive clear cell RCC. Differences between the genomic subtypes suggest that therapeutic strategies could be tailored to each RCC disease subset.
Published: 2016
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26. The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

Author: Christopher J. Ricketts, Aguirre A. De Cubas, Huihui Fan, Christof C. Smith, Martin Lang, Ed Reznik, Reanne Bowlby, Ewan A. Gibb, Rehan Akbani, Rameen Beroukhim, Donald P. Bottaro, Toni K. Choueiri, Richard A. Gibbs, Andrew K. Godwin, Scott Haake, A. Ari Hakimi, Elizabeth P. Henske, James J. Hsieh, Thai H. Ho, Rupa S. Kanchi, Bhavani Krishnan, David J. Kwaitkowski, Wembin Lui, Maria J. Merino, Gordon B. Mills, Jerome Myers, Michael L. Nickerson, Victor E. Reuter, Laura S. Schmidt, C. Simon Shelley, Hui Shen, Brian Shuch, Sabina Signoretti, Ramaprasad Srinivasan, Pheroze Tamboli, George Thomas, Benjamin G. Vincent, Cathy D. Vocke, David A. Wheeler, Lixing Yang, William T. Kim, A. Gordon Robertson, Paul T. Spellman, W. Kimryn Rathmell, W. Marston Linehan, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, Timothy DeFreitas, Scott Frazer, Nils Gehlenborg, Gad Getz, David I. Heiman, Jaegil Kim, Michael S. Lawrence, Pei Lin, Sam Meier, Michael S. Noble, Gordon Saksena, Doug Voet, Hailei Zhang, Brady Bernard, Nyasha Chambwe, Varsha Dhankani, Theo Knijnenburg, Roger Kramer, Kalle Leinonen, Yuexin Liu, Michael Miller, Sheila Reynolds, Ilya Shmulevich, Vesteinn Thorsson, Wei Zhang, Bradley M. Broom, Apurva M. Hegde, Zhenlin Ju, Anil Korkut, Jun Li, Han Liang, Shiyun Ling, Wenbin Liu, Yiling Lu, Kwok-Shing Ng, Arvind Rao, Michael Ryan, Jing Wang, John N. Weinstein, Jiexin Zhang, Adam Abeshouse, Joshua Armenia, Debyani Chakravarty, Walid K. Chatila, Ino de Bruijn, Jianjiong Gao, Benjamin E. Gross, Zachary J. Heins, Ritika Kundra, Konnor La, Marc Ladanyi, Augustin Luna, Moriah G. Nissan, Angelica Ochoa, Sarah M. Phillips, Francisco Sanchez-Vega, Chris Sander, Nikolaus Schultz, Robert Sheridan, S. Onur Sumer, Yichao Sun, Barry S. Taylor, Jioajiao Wang, Hongxin Zhang, Pavana Anur, Myron Peto, Paul Spellman, Christopher Benz, Joshua M. Stuart, Christopher K. Wong, Christina Yau, D. Neil Hayes, Joel S. Parker, Matthew D. Wilkerson, Adrian Ally, Miruna Balasundaram, Denise Brooks, Rebecca Carlsen, Eric Chuah, Noreen Dhalla, Robert Holt, Steven J.M. Jones, Katayoon Kasaian, Darlene Lee, Yussanne Ma, Marco A. Marra, Michael Mayo, Richard A. Moore, Andrew J. Mungall, Karen Mungall, Sara Sadeghi, Jacqueline E. Schein, Payal Sipahimalani, Angela Tam, Nina Thiessen, Kane Tse, Tina Wong, Ashton C. Berger, Andrew D. Cherniack, Carrie Cibulskis, Stacey B. Gabriel, Galen F. Gao, Gavin Ha, Matthew Meyerson, Steven E. Schumacher, Juliann Shih, Melanie H. Kucherlapati, Raju S. Kucherlapati, Stephen Baylin, Leslie Cope, Ludmila Danilova, Moiz S. Bootwalla, Phillip H. Lai, Dennis T. Maglinte, David J. Van Den Berg, Daniel J. Weisenberger, J. Todd Auman, Saianand Balu, Tom Bodenheimer, Cheng Fan, Katherine A. Hoadley, Alan P. Hoyle, Stuart R. Jefferys, Corbin D. Jones, Shaowu Meng, Piotr A. Mieczkowski, Lisle E. Mose, Amy H. Perou, Charles M. Perou, Jeffrey Roach, Yan Shi, Janae V. Simons, Tara Skelly, Matthew G. Soloway, Donghui Tan, Umadevi Veluvolu, Toshinori Hinoue, Peter W. Laird, Wanding Zhou, Michelle Bellair, Kyle Chang, Kyle Covington, Chad J. Creighton, Huyen Dinh, HarshaVardhan Doddapaneni, Lawrence A. Donehower, Jennifer Drummond, Robert Glenn, Walker Hale, Yi Han, Jianhong Hu, Viktoriya Korchina, Sandra Lee, Lora Lewis, Wei Li, Xiuping Liu, Margaret Morgan, Donna Morton, Donna Muzny, Jireh Santibanez, Margi Sheth, Eve Shinbrot, Linghua Wang, Min Wang, Liu Xi, Fengmei Zhao, Julian Hess, Elizabeth L. Appelbaum, Matthew Bailey, Matthew G. Cordes, Li Ding, Catrina C. Fronick, Lucinda A. Fulton, Robert S. Fulton, Cyriac Kandoth, Elaine R. Mardis, Michael D. McLellan, Christopher A. Miller, Heather K. Schmidt, Richard K. Wilson, Daniel Crain, Erin Curley, Johanna Gardner, Kevin Lau, David Mallery, Scott Morris, Joseph Paulauskis, Robert Penny, Candace Shelton, Troy Shelton, Mark Sherman, Eric Thompson, Peggy Yena, Jay Bowen, Julie M. Gastier-Foster, Mark Gerken, Kristen M. Leraas, Tara M. Lichtenberg, Nilsa C. Ramirez, Lisa Wise, Erik Zmuda, Niall Corcoran, Tony Costello, Christopher Hovens, Andre L. Carvalho, Ana C. de Carvalho, José H. Fregnani, Adhemar Longatto-Filho, Rui M. Reis, Cristovam Scapulatempo-Neto, Henrique C.S. Silveira, Daniel O. Vidal, Andrew Burnette, Jennifer Eschbacher, Beth Hermes, Ardene Noss, Rosy Singh, Matthew L. Anderson, Patricia D. Castro, Michael Ittmann, David Huntsman, Bernard Kohl, Xuan Le, Richard Thorp, Chris Andry, Elizabeth R. Duffy, Vladimir Lyadov, Oxana Paklina, Galiya Setdikova, Alexey Shabunin, Mikhail Tavobilov, Christopher McPherson, Ronald Warnick, Ross Berkowitz, Daniel Cramer, Colleen Feltmate, Neil Horowitz, Adam Kibel, Michael Muto, Chandrajit P. Raut, Andrei Malykh, Jill S. Barnholtz-Sloan, Wendi Barrett, Karen Devine, Jordonna Fulop, Quinn T. Ostrom, Kristen Shimmel, Yingli Wolinsky, Andrew E. Sloan, Agostino De Rose, Felice Giuliante, Marc Goodman, Beth Y. Karlan, Curt H. Hagedorn, John Eckman, Jodi Harr, Kelinda Tucker, Leigh Anne Zach, Brenda Deyarmin, Hai Hu, Leonid Kvecher, Caroline Larson, Richard J. Mural, Stella Somiari, Ales Vicha, Tomas Zelinka, Joseph Bennett, Mary Iacocca, Brenda Rabeno, Patricia Swanson, Mathieu Latour, Louis Lacombe, Bernard Têtu, Alain Bergeron, Mary McGraw, Susan M. Staugaitis, John Chabot, Hanina Hibshoosh, Antonia Sepulveda, Tao Su, Timothy Wang, Olga Potapova, Olga Voronina, Laurence Desjardins, Odette Mariani, Sergio Roman-Roman, Xavier Sastre, Marc-Henri Stern, Feixiong Cheng, Andrew Berchuck, Darell Bigner, Eric Lipp, Jeffrey Marks, Shannon McCall, Roger McLendon, Angeles Secord, Alexis Sharp, Madhusmita Behera, Daniel J. Brat, Amy Chen, Keith Delman, Seth Force, Fadlo Khuri, Kelly Magliocca, Shishir Maithel, Jeffrey J. Olson, Taofeek Owonikoko, Alan Pickens, Suresh Ramalingam, Dong M. Shin, Gabriel Sica, Erwin G. Van Meir, Hongzheng Zhang, Wil Eijckenboom, Ad Gillis, Esther Korpershoek, Leendert Looijenga, Wolter Oosterhuis, Hans Stoop, Kim E. van Kessel, Ellen C. Zwarthoff, Chiara Calatozzolo, Lucia Cuppini, Stefania Cuzzubbo, Francesco DiMeco, Gaetano Finocchiaro, Luca Mattei, Alessandro Perin, Bianca Pollo, Chu Chen, John Houck, Pawadee Lohavanichbutr, Arndt Hartmann, Christine Stoehr, Robert Stoehr, Helge Taubert, Sven Wach, Bernd Wullich, Witold Kycler, Dawid Murawa, Maciej Wiznerowicz, Ki Chung, W. Jeffrey Edenfield, Julie Martin, Eric Baudin, Glenn Bubley, Raphael Bueno, Assunta De Rienzo, William G. Richards, Steven Kalkanis, Tom Mikkelsen, Houtan Noushmehr, Lisa Scarpace, Nicolas Girard, Marta Aymerich, Elias Campo, Eva Giné, Armando López Guillermo, Nguyen Van Bang, Phan Thi Hanh, Bui Duc Phu, Yufang Tang, Howard Colman, Kimberley Evason, Peter R. Dottino, John A. Martignetti, Hani Gabra, Hartmut Juhl, Teniola Akeredolu, Serghei Stepa, Dave Hoon, Keunsoo Ahn, Koo Jeong Kang, Felix Beuschlein, Anne Breggia, Michael Birrer, Debra Bell, Mitesh Borad, Alan H. Bryce, Erik Castle, Vishal Chandan, John Cheville, John A. Copland, Michael Farnell, Thomas Flotte, Nasra Giama, Thai Ho, Michael Kendrick, Jean-Pierre Kocher, Karla Kopp, Catherine Moser, David Nagorney, Daniel O’Brien, Brian Patrick O’Neill, Tushar Patel, Gloria Petersen, Florencia Que, Michael Rivera, Lewis Roberts, Robert Smallridge, Thomas Smyrk, Melissa Stanton, R. Houston Thompson, Michael Torbenson, Ju Dong Yang, Lizhi Zhang, Fadi Brimo, Jaffer A. Ajani, Ana Maria Angulo Gonzalez, Carmen Behrens, Jolanta Bondaruk, Russell Broaddus, Bogdan Czerniak, Bita Esmaeli, Junya Fujimoto, Jeffrey Gershenwald, Charles Guo, Alexander J. Lazar, Christopher Logothetis, Funda Meric-Bernstam, Cesar Moran, Lois Ramondetta, David Rice, Anil Sood, Timothy Thompson, Patricia Troncoso, Anne Tsao, Ignacio Wistuba, Candace Carter, Lauren Haydu, Peter Hersey, Valerie Jakrot, Hojabr Kakavand, Richard Kefford, Kenneth Lee, Georgina Long, Graham Mann, Michael Quinn, Robyn Saw, Richard Scolyer, Kerwin Shannon, Andrew Spillane, onathan Stretch, Maria Synott, John Thompson, James Wilmott, Hikmat Al-Ahmadie, Timothy A. Chan, Ronald Ghossein, Anuradha Gopalan, Douglas A. Levine, Victor Reuter, Samuel Singer, Bhuvanesh Singh, Nguyen Viet Tien, Thomas Broudy, Cyrus Mirsaidi, Praveen Nair, Paul Drwiega, Judy Miller, Jennifer Smith, Howard Zaren, Joong-Won Park, Nguyen Phi Hung, Electron Kebebew, Adam R. Metwalli, Karel Pacak, Peter A. Pinto, Mark Schiffman, Nicolas Wentzensen, Robert Worrell, Hannah Yang, Marc Moncrieff, Chandra Goparaju, Jonathan Melamed, Harvey Pass, Natalia Botnariuc, Irina Caraman, Mircea Cernat, Inga Chemencedji, Adrian Clipca, Serghei Doruc, Ghenadie Gorincioi, Sergiu Mura, Maria Pirtac, Irina Stancul, Diana Tcaciuc, Monique Albert, Iakovina Alexopoulou, Angel Arnaout, John Bartlett, Jay Engel, Sebastien Gilbert, Jeremy Parfitt, Harman Sekhon, Doris M. Rassl, Robert C. Rintoul, Carlo Bifulco, Raina Tamakawa, Walter Urba, Nicholas Hayward, Henri Timmers, Anna Antenucci, Francesco Facciolo, Gianluca Grazi, Mirella Marino, Roberta Merola, Ronald de Krijger, Anne-Paule Gimenez-Roqueplo, Alain Piché, Simone Chevalier, Ginette McKercher, Kivanc Birsoy, Gene Barnett, Cathy Brewer, Carol Farver, Theresa Naska, Nathan A. Pennell, Daniel Raymond, Cathy Schilero, Kathy Smolenski, Felicia Williams, Carl Morrison, Jeffrey A. Borgia, Michael J. Liptay, Mark Pool, Christopher W. Seder, Kerstin Junker, Larsson Omberg, Mikhail Dinkin, George Manikhas, Domenico Alvaro, Maria Consiglia Bragazzi, Vincenzo Cardinale, Guido Carpino, Eugenio Gaudio, David Chesla, Sandra Cottingham, Michael Dubina, Fedor Moiseenko, Renumathy Dhanasekaran, Karl-Friedrich Becker, Klaus-Peter Janssen, Julia Slotta-Huspenina, Mohamed H. Abdel-Rahman, Dina Aziz, Sue Bell, Colleen M. Cebulla, Amy Davis, Rebecca Duell, J. Bradley Elder, Joe Hilty, Bahavna Kumar, James Lang, Norman L. Lehman, Randy Mandt, Phuong Nguyen, Robert Pilarski, Karan Rai, Lynn Schoenfield, Kelly Senecal, Paul Wakely, Paul Hansen, Ronald Lechan, James Powers, Arthur Tischler, William E. Grizzle, Katherine C. Sexton, Alison Kastl, Joel Henderson, Sima Porten, Jens Waldmann, Martin Fassnacht, Sylvia L. Asa, Dirk Schadendorf, Marta Couce, Markus Graefen, Hartwig Huland, Guido Sauter, Thorsten Schlomm, Ronald Simon, Pierre Tennstedt, Oluwole Olabode, Mark Nelson, Oliver Bathe, Peter R. Carroll, June M. Chan, Philip Disaia, Pat Glenn, Robin K. Kelley, Charles N. Landen, Joanna Phillips, Michael Prados, Jeffry Simko, Karen Smith-McCune, Scott VandenBerg, Kevin Roggin, Ashley Fehrenbach, Ady Kendler, Suzanne Sifri, Ruth Steele, Antonio Jimeno, Francis Carey, Ian Forgie, Massimo Mannelli, Michael Carney, Brenda Hernandez, Benito Campos, Christel Herold-Mende, Christin Jungk, Andreas Unterberg, Andreas von Deimling, Aaron Bossler, Joseph Galbraith, Laura Jacobus, Michael Knudson, Tina Knutson, Deqin Ma, Mohammed Milhem, Rita Sigmund, Rashna Madan, Howard G. Rosenthal, Clement Adebamowo, Sally N. Adebamowo, Alex Boussioutas, David Beer, Thomas Giordano, Anne-Marie Mes-Masson, Fred Saad, Therese Bocklage, Lisa Landrum, Robert Mannel, Kathleen Moore, Katherine Moxley, Russel Postier, Joan Walker, Rosemary Zuna, Michael Feldman, Federico Valdivieso, Rajiv Dhir, James Luketich, Edna M. Mora Pinero, Mario Quintero-Aguilo, Carlos Gilberto Carlotti, Jr., Jose Sebastião Dos Santos, Rafael Kemp, Ajith Sankarankuty, Daniela Tirapelli, James Catto, Kathy Agnew, Elizabeth Swisher, Jenette Creaney, Bruce Robinson, Carl Simon Shelley, Eryn M. Godwin, Sara Kendall, Cassaundra Shipman, Carol Bradford, Thomas Carey, Andrea Haddad, Jeffey Moyer, Lisa Peterson, Mark Prince, Laura Rozek, Gregory Wolf, Rayleen Bowman, Kwun M. Fong, Ian Yang, Robert Korst, J. Leigh Fantacone-Campbell, Jeffrey A. Hooke, Albert J. Kovatich, Craig D. Shriver, John DiPersio, Bettina Drake, Ramaswamy Govindan, Sharon Heath, Timothy Ley, Brian Van Tine, Peter Westervelt, Mark A. Rubin, Jung Il Lee, Natália D. Aredes, and Armaz Mariamidze
Subjects: Biology (General), QH301-705.5
Abstract: Summary: Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with different genetic drivers, clinical courses, and therapeutic responses. The current study evaluated 843 RCC from the three major histologic subtypes, including 488 clear cell RCC, 274 papillary RCC, and 81 chromophobe RCC. Comprehensive genomic and phenotypic analysis of the RCC subtypes reveals distinctive features of each subtype that provide the foundation for the development of subtype-specific therapeutic and management strategies for patients affected with these cancers. Somatic alteration of BAP1, PBRM1, and PTEN and altered metabolic pathways correlated with subtype-specific decreased survival, while CDKN2A alteration, increased DNA hypermethylation, and increases in the immune-related Th2 gene expression signature correlated with decreased survival within all major histologic subtypes. CIMP-RCC demonstrated an increased immune signature, and a uniform and distinct metabolic expression pattern identified a subset of metabolically divergent (MD) ChRCC that associated with extremely poor survival. : Ricketts et al. find distinctive features of each RCC subtype, providing the foundation for development of subtype-specific therapeutic and management strategies. Somatic alteration of BAP1, PBRM1, and metabolic pathways correlates with subtype-specific decreased survival, while CDKN2A alteration, DNA hypermethylation, and Th2 immune signature correlate with decreased survival within all subtypes. Keywords: clear cell renal cell carcinoma, papillary renal cell carcinoma, chromophobe renal cell carcinoma, CDKN2A, DNA hypermethylation, immune signature, chromatin remodeling, TCGA, PanCanAtlas
Published: 2018
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27. Behavior of blood plasma glycan features in bladder cancer.

Author: Shadi Ferdosi, Thai H Ho, Erik P Castle, Melissa L Stanton, and Chad R Borges
Subjects: Medicine, Science
Abstract: Despite systemic therapy and cystectomy, bladder cancer is characterized by a high recurrence rate. Serum glycomics represents a promising source of prognostic markers for monitoring patients. Our approach, which we refer to as "glycan node analysis", constitutes the first example of molecularly "bottom-up" glycomics. It is based on a global glycan methylation analysis procedure that is applied to whole blood plasma/serum. The approach detects and quantifies partially methylated alditol acetates arising from unique glycan features such as α2-6 sialylation, β1-4 branching, and core fucosylation that have been pooled together from across all intact glycans within a sample into a single GC-MS chromatographic peak. We applied this method to 122 plasma samples from former and current bladder cancer patients (n = 72 former cancer patients with currently no evidence of disease (NED); n = 38 non-muscle invasive bladder cancer (NMIBC) patients; and n = 12 muscle invasive bladder cancer (MIBC) patients) along with plasma from 30 certifiably healthy living kidney donors. Markers for α2-6 sialylation, β1-4 branching, β1-6 branching, and outer-arm fucosylation were able to separate current and former (NED) cases from certifiably healthy controls (ROC curve c-statistics ~ 0.80); but NED, NMIBC, and MIBC were not distinguished from one another. Based on the unexpectedly high levels of these glycan nodes in the NED patients, we hypothesized that recurrence of this disease could be predicted by some of the elevated glycan features. Indeed, α2-6 sialylation and β1-6 branching were able to predict recurrence from the NED state using a Cox proportional hazards regression model adjusted for age, gender, and time from cancer. The levels of these two glycan features were correlated to C-reactive protein concentration, an inflammation marker and known prognostic indicator for bladder cancer, further strengthening the link between inflammation and abnormal plasma protein glycosylation.
Published: 2018
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28. Inhibition of intracellular lipolysis promotes human cancer cell adaptation to hypoxia

Author: Xiaodong Zhang, Alicia M Saarinen, Taro Hitosugi, Zhenghe Wang, Liguo Wang, Thai H Ho, and Jun Liu
Subjects: lipid droplet, lipolysis, hypoxia, cancer metabolism, fatty acid oxidation, reactive oxygen species, Medicine, Science, Biology (General), QH301-705.5
Abstract: Tumor tissues are chronically exposed to hypoxia owing to aberrant vascularity. Lipid droplet (LD) accumulation is a hallmark of hypoxic cancer cells, yet how LDs form and function during hypoxia remains poorly understood. Herein, we report that in various cancer cells upon oxygen deprivation, HIF-1 activation down-modulates LD catabolism mediated by adipose triglyceride lipase (ATGL), the key enzyme for intracellular lipolysis. Proteomics and functional analyses identified hypoxia-inducible gene 2 (HIG2), a HIF-1 target, as a new inhibitor of ATGL. Knockout of HIG2 enhanced LD breakdown and fatty acid (FA) oxidation, leading to increased ROS production and apoptosis in hypoxic cancer cells as well as impaired growth of tumor xenografts. All of these effects were reversed by co-ablation of ATGL. Thus, by inhibiting ATGL, HIG2 acts downstream of HIF-1 to sequester FAs in LDs away from the mitochondrial pathways for oxidation and ROS generation, thereby sustaining cancer cell survival in hypoxia.
Published: 2017
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29. Energy Flexibility from Large Prosumers to Support Distribution System Operation—A Technical and Legal Case Study on the Amsterdam ArenA Stadium

Author: Dirk Kuiken, Heyd F. Más, Maryam Haji Ghasemi, Niels Blaauwbroek, Thai H. Vo, Thijs van der Klauw, and Phuong H. Nguyen
Subjects: congestion management, demand side management (DSM), distribution system operation, electric vehicles, energy flexibility, legal framework, storage system, Technology
Abstract: To deal with the rising integration of stochastic renewables and energy intensive distributed energy resources (DER) to the electricity network, alternatives to expensive network reinforcements are increasingly needed. An alternative solution often under consideration is integrating flexibility from the consumer side to system management. However, such a solution needs to be contemplated from different angles before it can be implemented in practice. To this end, this article considers a case study of the Amsterdam ArenA stadium and its surrounding network where flexibility is expected to be available to support the network in the future. The article studies the technical aspects of using this flexibility to determine to what extent, despite the different, orthogonal goals, the available flexibility can be used by various stakeholders in scenarios with a large load from electric vehicle charging points. Furthermore, a legal study is performed to determine the feasibility of the technical solutions proposed by analysing current European Union (EU) and Dutch law and focusing on the current agreements existing between the parties involved. The article shows that flexibility in the network provided by Amsterdam ArenA is able to significantly increase the number of charging points the network can accommodate. Nonetheless, while several uses of flexibility are feasible under current law, the use of flexibility provided by electric vehicles specifically faces several legal challenges in current arrangements.
Published: 2018
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30. A Multidisciplinary Biospecimen Bank of Renal Cell Carcinomas Compatible with Discovery Platforms at Mayo Clinic, Scottsdale, Arizona.

Author: Thai H Ho, Rafael Nunez Nateras, Huihuang Yan, Jin G Park, Sally Jensen, Chad Borges, Jeong Heon Lee, Mia D Champion, Raoul Tibes, Alan H Bryce, Estrella M Carballido, Mark A Todd, Richard W Joseph, William W Wong, Alexander S Parker, Melissa L Stanton, and Erik P Castle
Subjects: Medicine, Science
Abstract: To address the need to study frozen clinical specimens using next-generation RNA, DNA, chromatin immunoprecipitation (ChIP) sequencing and protein analyses, we developed a biobank work flow to prospectively collect biospecimens from patients with renal cell carcinoma (RCC). We describe our standard operating procedures and work flow to annotate pathologic results and clinical outcomes. We report quality control outcomes and nucleic acid yields of our RCC submissions (N=16) to The Cancer Genome Atlas (TCGA) project, as well as newer discovery platforms, by describing mass spectrometry analysis of albumin oxidation in plasma and 6 ChIP sequencing libraries generated from nephrectomy specimens after histone H3 lysine 36 trimethylation (H3K36me3) immunoprecipitation. From June 1, 2010, through January 1, 2013, we enrolled 328 patients with RCC. Our mean (SD) TCGA RNA integrity numbers (RINs) were 8.1 (0.8) for papillary RCC, with a 12.5% overall rate of sample disqualification for RIN
Published: 2015
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31. Omeprazole blocks STAT6 binding to the eotaxin-3 promoter in eosinophilic esophagitis cells.

Author: Xi Zhang, Edaire Cheng, Xiaofang Huo, Chunhua Yu, Qiuyang Zhang, Thai H Pham, David H Wang, Stuart J Spechler, and Rhonda F Souza
Subjects: Medicine, Science
Abstract: Patients who have esophageal eosinophilia without gastroesophageal reflux disease (GERD) nevertheless can respond to proton pump inhibitors (PPIs), which can have anti-inflammatory actions independent of effects on gastric acid secretion. In esophageal cell cultures, omeprazole has been reported to inhibit Th2 cytokine-stimulated expression of eotaxin-3, an eosinophil chemoattractant contributing to esophageal eosinophilia in eosinophilic esophagitis (EoE). The objective of this study was to elucidate molecular mechanisms underlying PPI inhibition of IL-4-stimulated eotaxin-3 production by esophageal cells.Telomerase-immortalized and primary cultures of esophageal squamous cells from EoE patients were treated with IL-4 in the presence or absence of acid-activated omeprazole or lansoprazole. We measured eotaxin-3 protein secretion by ELISA, mRNA expression by PCR, STAT6 phosphorylation and nuclear translocation by Western blotting, eotaxin-3 promoter activation by an exogenous reporter construct, and STAT6, RNA polymerase II, and trimethylated H3K4 binding to the endogenous eotaxin-3 promoter by ChIP assay. Omeprazole in concentrations ≥5 µM significantly decreased IL-4-stimulated eotaxin-3 protein secretion and mRNA expression. Lansoprazole also blocked eotaxin-3 protein secretion. Omeprazole had no effect on eotaxin-3 mRNA stability or on STAT6 phosphorylation and STAT6 nuclear translocation. Rather, omeprazole blocked binding of IL-4-stimulated STAT6, RNA polymerase II, and trimethylated H3K4 to the eotaxin-3 promoter.PPIs, in concentrations achieved in blood with conventional dosing, significantly inhibit IL-4-stimulated eotaxin-3 expression in EoE esophageal cells and block STAT6 binding to the promoter. These findings elucidate molecular mechanisms whereby patients with Th2 cytokine-driven esophageal eosinophilia can respond to PPIs, independent of effects on gastric acid secretion.
Published: 2012
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32. The risks of failed nonoperative management of appendicitis in older adults

Author: Lunardi, Nicole, Marten, Elisa, Sharath, Sherene, Kougias, Panos, Pham, Thai H., and Balentine, Courtney J.
Published: 2024
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33. Cancer associated macrophage-like cells in metastatic renal cell carcinoma predicts for poor prognosis and tracks treatment response in real time

Author: Ali, Amama, Adams, Daniel L., Kasabwala, Dimpal M., Tang, Cha-Mei, and Ho, Thai H.
Published: 2023
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34. Extensive intratumor regional epigenetic heterogeneity in clear cell renal cell carcinoma targets kidney enhancers and is associated with poor outcome

Author: El Khoury, Louis Y., Pan, Xiaoyu, Hlady, Ryan A., Wagner, Ryan T., Shaikh, Shafiq, Wang, Liguo, Humphreys, Mitchell R., Castle, Erik P., Stanton, Melissa L., Ho, Thai H., and Robertson, Keith D.
Published: 2023
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35. Is nonoperative management of appendicitis safe and effective in multi-morbid patients?

Author: Lunardi, Nicole, Meier, Jennie, Pham, Thai H., Zarzaur, Ben L., Agarwal, Suresh, Sharath, Sherene, Kougias, Panos, and Balentine, Courtney J.
Published: 2024
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36. Face Generation from Skull Photo Using GAN and 3D Face Models

Author: Vo, Duy K., Bui, Len T., Le, Thai H., Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, and Arai, Kohei, editor
Published: 2023
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37. Clinical Results and Biomarker Analyses of Axitinib and TRC105 versus Axitinib Alone in Patients with Advanced or Metastatic Renal Cell Carcinoma (TRAXAR)

Author: Choueiri, Toni K, Zakharia, Yousef, Pal, Sumanta, Kocsis, Judit, Pachynski, Russell, Poprach, Alexandr, Nixon, Andrew B, Liu, Yingmiao, Starr, Mark, Lyu, Jing, Owzar, Kouros, deShazo, Mollie, Lara, Primo, Geczi, Lajos, Ho, Thai H, Walsh, Meghara, Adams, Bonne, Robertson, Liz, Darif, Mohamed, Theuer, Charles, and Agarwal, Neeraj
Subjects: Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Cancer, Clinical Research, Kidney Disease, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, 6.2 Cellular and gene therapies, Antibodies, Monoclonal, Axitinib, Carcinoma, Renal Cell, Humans, Kidney Neoplasms, Vascular Endothelial Growth Factor A, Phase II, TRAXAR, Renal cell cancer, Endoglin, TRC105, Carotuximab, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract: Lessons learnedThe combination of carotuximab with axitinib did not provide a benefit over axitinib monotherapy in patients with metastatic clear cell renal cell carcinoma who had previously progressed on one or more vascular endothelial growth factor (VEGF)-targeted therapies. Exploratory evaluation of pretreatment circulating biomarkers suggested the combination might benefit patients who have low baseline VEGF levels.BackgroundEndoglin is an angiogenic receptor expressed on proliferating tumor vessels and renal cell carcinoma (RCC) stem cells that is implicated as a mechanism of resistance to vascular endothelial growth factor receptor (VEGFR) inhibitors. This study evaluated an antiendoglin monoclonal antibody (carotuximab, TRC105) combined with axitinib in patients with advanced or metastatic clear cell renal cell carcinoma (mccRCC) who had progressed following one or more prior VEGF inhibitors.MethodsTRAXAR was a multicenter, international randomized 1:1 (stratified by ECOG, 0 vs. 1), phase II study of carotuximab combined with axitinib versus axitinib alone in mccRCC patients who had progressed following one or more prior VEGF inhibitors. The primary endpoint was progression-free survival (PFS) assessed by independent central review (ICR) per RECIST 1.1 RESULTS: A total of 150 patients were randomized. The combination therapy resulted in shorter median PFS by RECIST 1.1 than axitinib monotherapy (6.7 vs. 11.4 months). The combination was tolerated similarly to axitinib monotherapy, and there were no treatment related deaths. Exploratory evaluation of pretreatment circulating biomarkers suggested the combination might benefit patients who have low baseline VEGF levels.ConclusionThe combination of carotuximab with axitinib did not demonstrate additional efficacy over single agent axitinib in patients with mccRCC who progressed following one or more prior VEGF inhibitor treatment.
Published: 2021

38. Generation and characterization of a monoclonal antibody that binds to Galectin-1

Author: Pfeffer, Kirsten, Ho, Thai H., Grill, Francisca J., Ruiz, Yvette, and Lake, Douglas F.
Published: 2023
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39. Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial

Author: Abani, Obbina, Abbas, Ali, Abbas, Fatima, Abbas, Joshua, Abbas, Kasim, Abbas, Mustafa, Abbasi, Sadia, Abbass, Hakam, Abbott, Alfie, Abbott, Alison, Abdallah, Nabeel, Abdelaziz, Ammar, Abdelaziz, Ashraf, Abdelfattah, Mohamed, Abdelqader, Bushra, Abdul, Audrey, Abdul, Basir, Abdul, Siddiqui, Abdul Rasheed, Althaf, Abdulakeem, Ajibode, Abdul-Kadir, Rezan, Abdullah, Abdullah, Abdulmumeen, Abdulfatahi, Abdul-Raheem, Rasheed, Abdulshukkoor, Niyaz, Abdusamad, Kula, Abed El Khaleq, Yazeed, Abedalla, Mai, Abeer Ul Amna, Abeer, Abel, Lynn, Abernethy, Katrina, Abeywickrema, Movin, Abhinaya, Chandra, Abidin, Affyarsyah, Aboaba, Adebanke, Aboagye-Odei, Abigail, Aboah, Christopher, Aboelela, Heba, Abo-Leyah, Hani, Abouelela, Karim, Abou-Haggar, Ahmed, Abouibrahim, Mahmoud, Abousamra, Ahmed, Abouzaid, Mona, Abraham, Miriam, Abraham, Tizzy, Abraheem, Abraheem, Abrams, Judith, Abrams, Rebecca, Abu, Hyacinth-John, Abu-Arafeh, Ahmed, Abubacker, Syed M, Abung, Akata, Abusamra, Yousuf, Aceampong, Yaa, Achara, Amaka, Acharya, Devikumar, Acheampong, Faustina, Acheampong, Prince, Acheampong, Sarah, Acheson, Janet, Achieng, Shiella, Acosta, Andres, Acquah, Rebecca, Acton, Catherine, Adabie-Ankrah, Jacqueline, Adair, Paul, Adam, Fiona, Adam, Matthew, Adamali, Huzaifa, Adamczyk, Marta, Adams, Carol, Adams, Charlotte, Adams, Daniel, Adams, Kate, Adams, Laura, Adams, Nikkita, Adams, Richard, Adams, Tim, Adamu-Ikeme, Laura, Adatia, Krishma, Adcock, Kirsty, Addai-Boampong, Lawrence, Addo, Afua, Adeagbo, Oluwatobi, Adebiyi, Ade, Adedeji, Ogunlana, Adegeye, Yewande, Adegoke, Ken, Adell, Vicki, Adenwalla, Sherna, Adeoye, Femi W, Adesemoye, Oluwasegun A, Adewunmi, Emmanuel O, Adeyanju, Adedamola, Adeyemi, Joyce, Adeyemo, Tenifayo, Adhikari, Binay, Adhikari, Shanti A, Adhikary, Rina, Aditya, Adhikarla, Adjepong, Patience, Adkins, Gabrielle, Adnan, Adnan, Adriaanse, Marguerite, Aeron-Thomas, John, Affleck, Debbie, Afnan, Carmel, Afridi, Muhammad, Afrim, Patricia, Afriyie, Felicia Akua, Aftab, Zainab A, Agarwal, Meenakshi, Agbeko, Rachel, Agbo, Chris, Aggarwal, Sunil, Aghababaie, Arameh, Aguilar Jimenez, Laura, Agyekum, Jacqueline Afrakomah, Agyen, Kwame, Ahamed Sadiq, Shafana, Ahammed Nazeer, Mohamed H, Ahmad, Mohammad, Ahmad, Syed, Ahmed, Afshan, Ahmed, Ashar, Ahmed, Asim, Ahmed, Basheer A R, Ahmed, Bilal, Ahmed, Forizuddin, Ahmed, Hamze, Ahmed, Hanad, Ahmed, Irshad, Ahmed, Khaled, Ahmed, Khalil, Ahmed, Liban, Ahmed, Mahin, Ahmed, Maria C, Ahmed, Muhammad S, Ahmed, Naseer, Ahmed, Nausheen, Ahmed, Osama, Ahmed, Rajia A, Ahmed, Rawya, Ahmed, Rizwan, Ahmed, Saif, Ahmed, Sammiya, Ahmed, Sana G, Ahmed, Syed, Ahmed, Syed H, Ahmed Ali, Roa, Ahmed Mohamud, Bilal, Ahmed, Sana, Ahmer, Sana, Ahonia, Augustine, Aiken, Christine, Ail, Dhiraj, Ainsworth, Mark, Aissa, Myriam, Aitken, Lindianne, Ajay, Bini, Ajibode, Abdulakeem, Ajmi, Ayesha, Akhtar, Nasim, Akhtar, Nauman, Akili, Suha, Akinbiyi, Bolutito, Akindolie, Oludoyinsola, Akinfenwa, Yinka, Akinkugbe, Olugbenga, Akinpelu, Ibrahim, Akram, Mohammad, Aktinade, Olugbenro, Akudi, Uzayr, Al Aaraj, Ahmad S A R, Al Balushi, Asma, Al Dakhola, Majd, Al Swaifi, Aladdin, Al-Abadi, Eslam, Alabi, Adegoke, Aladangady, Narendra, Alafifi, Mohamed, Alam, Ayaz, Alam, Sajid, Al-Asadi, Abbas, Alatzoglou, Kyriaki, Albert, Paul, Albertus, Albertus, Albon, Lorraine, Alcala, Angela, Alcorn, Gemma, Alcorn, Stephen, Aldana, Aggie, Alderdice, David, Aldesouki, Abdullah, Aldouri, Rayan, Aldridge, Jonathan, Aldridge, Nicolas, Ale, Ram Maya, Alegria, Ana, Alexander, Alison, Alexander, Courtney, Alexander, John, Alexander, Peter D G, Al-fori, Julyan, Alghazawi, Laith, Alhabsha, Osama, Al-Hakim, Bahij, Alhameed, Rafil, Al-Hayali, Mohammed, Al-Hity, Shams, Ali, Ali, Ali, Amanda, Ali, Asad, Ali, Fawzia R, Ali, Jawad, Ali, Mariam, Ali, Mohamed, Ali, Mohammad, Ali, Muhammad S, Ali, Nayab, Ali, Oudai, Ali, Ramla, Ali, Sakina, Ali, Syed, Aliberti, Emilio, Alin, Jade, Alina, Abid, Alipustain, Analyn, Alisjahbana, Bachti, Aliyuda, Fine, Alizadeh, Katrin, Al-Jibury, Maithem, Al-Juboori, Saba, Al-Khalil, Majid, Alkhudhayri, Abdullah, Alkhusheh, Moutaz, Allan, Fiona, Allan, Nataliya, Allanson, Alison, Allcock, Robert, Allen, Eireann, Allen, Jade, Allen, Kerry, Allen, Louise, Allen, Poppy, Allen, Rebecca, Allen, Sam, Allen, Sharon, Allen, Simon, Allen, Tania, Alli, Abiola, Allison, Kathryn, Allman, Bethan, Allsop, Helen K, Allsop, Lynne, Allsup, David, Almahroos, Amal F T, Al-Moasseb, Hassan, Al-Obaidi, Magda, Alomari, Lina, Al-Rabahi, Akram, Al-Ramadhani, Bahar, Al-Saadi, Zayneb, Al-Sammarraie, Riyam, Alshaer, Inji, Al-Shahi Salman, Rustam, Al-Shamkhani, Warkaq, Alsheikh, Fadia, Al-Sheklly, Bashar, Altaf, Sara, Alty, Amanda, Alvarez, Mary, Alvarez Corral, Maria, Alveyn, Edward, Alzetani, Maysaa, Amamou, Susan, Amar, Noor, Ambalavanan, Sakkarai, Ambrogetti, Robert, Ambrose, Chris, Ameen, Amir, Amelia Ganefianty, Amel, Ames, Katharine, Amezaga, Maria R, Amin, Allison, Amin, Amina, Amin, Kanish, Amin, Syed, Amin, Tara, Amit, Badshah, Amjad, Amjad, Amjad, Neelma, Amoah-Dankwa, James, Amosun, Victoria, Amsal, Muhammad, Amsha, Khaled, Amuasi, John, Amutio Martin, Noelia, Amy, Pugh, Anada, Ann, Anand, Atul, Anandappa, Samantha, Anantapatnaikuni, Satya D, Anderson, Ellen, Anderson, Julie, Anderson, Laura, Anderson, Marina, Anderson, Michelle, Anderson, Nicola, Anderson, Rachel, Anderson, Rebecca, Anderson, Rory, Anderson, Samantha, Anderson, Wendy, Andreou, Prematie, Andrews, Angela, Andrews, Antonette, Andrews, Jill, Andrews, Joyann, Aneke, Kanayochukwu, Ang, Andrew, Ang, Wan Wei, Angel, Tammy, Angela, Aramburo, Angelini, Paola, Anguvaa, Lazarus, Anichtchik, Oleg, Anim-Somuah, Millicent, Aniruddhan, Krishnan, Annett, Jessica, Anning, Louise, Ansah, Maldwyn, Anstey, Patrick J, Anstey, Rebekah, Anthony, Alpha, Anthony-Pillai, Aaron, Antill, Philip, Antonina, Zhelyazkova, Anu, Varghese, Anwar, Muhammad, Apetri, Elena, Apostolopoulos, Aristeidis, Appleby, Sarah, Appleyard, Diane, Aquino, Maia F, Araba, Bianca, Aransiola, Samuel, Araujo, Mariana, Archer, Ann, Archer, Denise, Archer, Samuel, Archer, Simon, Arcoria, Daniele, Ardley, Christian, Arias, Ana-Maria, Aribike, Oluwatoyin, Arimoto, Ryoki, Arkley, Charlotte, Armah, Charlotte, Armata, Ilianna, Armistead, Jennifer, Armitage, Adam, Armstrong, Ceri, Armstrong, Maureen, Armstrong, Sonia, Armstrong, Wendy, Armtrong, Philippa, Arndt, Heike, Arnison-Newgass, Clare, Arnold, David, Arnold, Rachael, Arnott, Andrew, Arora, Dhawal, Arora, Kavan, Arora, Pardeep, Arora, Rishi, Arter, Arslam, Arumaithurai, Armena, Arya, Ayush, Arya, Rita, Aryal, Diptesh, Asandei, Denisa, Asghar, Adeeba, Asghar, Malik, Ashab, Arif, Ashbrook-Raby, Catherine, Ashby, Helen, Ashcroft, Jan, Ashcroft, John, Ashcroft, Samuel, Asher, Georgia, Ashfak, Zakariya, Ashfaq, Ayesha, Ashish, Abdul, Ashley, Dawn, Ashman-Flavell, Sally, Ashok, Sundar, Ashour, Abd-El-Aziz, Ashraf, Muhammad Z, Ashraf, Saima, Ashraq, Mohammad B, Ashton, Deborah, Ashton, Susan, Ashworth, Andrew, Ashworth, Fiona J, Ashworth, Rebecca, Aslam, Arshia, Aslam, I, Aslam, Suhail, Aslett, Laura, Asogan, Harshini, Asrar, Atif, Assaf, Omar, Astin-Chamberlain, Raine, Athorne, Deborah, Atkins, Billie, Atkins, Christopher, Atkins, Stacey, Atkinson, John, Atkinson, Vicki, Atomode, Abolaji, Atraskiewicz, Brygitta, Attia, Abdul A, Attubato, Eva, Attwood, Marie, Aubrey, Paula, Auer, Zoltan, Aujayeb, Avinash, Aung, Aye Chan Thar, Aung, Hnin, Aung, Hnin Wint Wint, Aung, Ko Ko, Aung, Kyaw Thu, Aung, Nwe, Aung, Yin, Aung, Zaw Myo, Austin, Emily, Austin, Karen, Auwal, Abdusshakur, Avari, Malcolm, Avery, Miriam, Aveyard, Nicholas, Avis, Joanne, Aviss, Georgina, Avram, Cristina, Avram, Paula, Awadelkareem, Abuzar, Awadzi, Gabriel, Awaly, Mahmoud, Awan, Atia, Aya, Aszad, Ayaz, Eman, Ayerh, John Maximilian, Ayers, Amanda, Azam, Jawwad, Azeem, Ahmed, Azharuddin, Mohammed, Aziz, Ammar, Aziz, Ghazala, Aziz, Imran, Aziz, N, Azkoul, Ali, Azman Shah, Ashaari, Azzopardi, Giada, Azzoug, Hocine, Babatunde, Fiyinfoluwa, Babi, Melvin, Babiker, Babiker, Babington, Gayna, Babirecki, Matthew, Babores, Marta, Babs-Osibodu, Adetona O, Bacciarelli, Sammy, Bachar, Roudi, Bachour, Michel-Elie, Bachti, Alisjahbana, Bacon, Gina, Bacon, Jenny, Badal, Bibi, Badat, Aysha, Bader, Maryuma, Badhan, Gurpreet R, Badhrinarayanan, Shreya, Bae, Joseph P, Baggaley, Alice, Baggott, Amy, Bagley, Graham, Bagmane, Dinesh, Bagshaw, Lynsey, Bahadori, Kasra, Bailey, Angela, Bailey, James, Bailey, Katie, Bailey, Lindsey, Bailey, Liz, Bailey, Lucy, Bailey, Maria A, Bailey, Morgan, Bailey, Pippa, Bailey, Sarah, Baillie, Hamish, Baillie, J Kenneth, Bain, Jennifer, Bains, Vikram, Baird, David, Baird, Eilidh, Baird, Kevin, Baird, Susan, Baird, Tracy, Baird, Yolanda, Bajandouh, Aiysha, Baker, Danielle C, Baker, Evelyn, Baker, Johanne, Baker, Josephine, Baker, Kenneth, Baker, Mark, Baker, Rebecca, Baker, Terri-Anne, Baker, Victoria, Bakere, Hugh, Bakerly, Nawar, Baker-Moffatt, Michelle, Bakhai, Ameet, Bakhtiar, Nauman, Bakoulas, Panos, Bakthavatsalam, Dhanalakshmi, Balachandran, Niranjan, Balan, Andrea, Balasingam, Prasath, Balaskas, Theodosios, Balasubramaniam, Madhu, Balatoni, Nicola, Balcombe, Alison, Baldwin, Alexander, Baldwin, Ashley, Baldwin, Caron, Baldwin, Danielle, Baldwin, Fiona, Baldwin-Jones, Rebekah, Bale, Nichola, Balfour, James, Ball, Matthew, Ball, Robert, Ballard, K, Balluz, Ismael, Balmforth, Craig, Balogh, Emese, Baltmr, Abeir, Baluwala, Amir, Bambridge, Gabby, Bamford, Alasdair, Bamford, Amy, Bamford, Peter, Bamgboye, Adefunke, Bancroft, Elizabeth, Bancroft, Hollie, Banda, Joyce, Bandaru, Krishna, Bandi, Srini, Bandla, Nageswar, Bandyopadhyam, Somaditya, Banerjee, Amit, Banerjee, Ritwik, Baniya, Santosh, Bani-Saad, Omar, Banks, Harrison, Banks, Luke, Banks, Paul, Bann, Claudia, Bannister, Helen, Bannister, Oliver, Banton, Laura, Bao, Tran, Baptist, Mariamma, Baqai, Tanya, Baral, Ananya M, Baral, Sharad Chandra, Baramova, Desislava, Barber, Russel, Barbon, Emma, Barbosa, Monica, Barbour, Jamie, Barclay, Alexander, Barclay, Amanda, Barclay, Claire, Bardsley, George, Bareford, Stephanie, Bari, Shahedal, Barimbing, Morris, Barker, Amy, Barker, Debbie, Barker, Erandi, Barker, Helen, Barker, Joseph, Barker, Leon, Barker, Lesley, Barker, Oliver, Barker-Williams, Kerry, Barkha, Sinha, Barla, Juliana, Barlow, Gavin, Barlow, Richard, Barlow, Valerie, Barnacle, James, Barnard, Alex, Barnes, Debi, Barnes, Nicky, Barnes, Rory, Barnes, Theresa, Barnetson, Calum, Barnett, Amy, Barnett-Vanes, Ashton, Barning, Prince Gyenti, Barnsley, William, Barr, Andrew, Barr, David, Barr, James, Barr, Charlotte, Barratt, Nina, Barratt, Shaney, Barrera, Manuella, Barrett, Amy, Barrett, Fiona, Barrett, Jessica, Barrett, Sue, Barrow, Esther, Bartholomew, Jazz, Bartlett, Claire, Bartlett, Georgina, Bartlett, James, Bartlett, Louise, Bartley, Shauna, Bartolmeu-Pires, Sandra, Barton, Anna, Barton, Greg, Barton, Jill, Barton, Lorna, Barton, Rachael, Baruah, Rosaleen, Baryschpolec, Sonia, Bashir, Hannah, Bashyal, Archana, Basker, Betsy, Basnet, Sudha, Basnyat, Buddha, Basoglu, Ayten, Basran, Alexander, Bassett, John, Bassett, G, Bassford, Chris, Bassoy, Bengisu, Bastion, Victoria, Bastola, Anup, Basumatary, Anupam, Basvi, Precious, Batac, Jireh A, Bataduwaarachchi, Vipula R, Bate, Tristan, Bateman, Harry J, Bateman, Kathryn, Bateman, Vhairi, Bates, Eleanor, Bates, Hayley, Bates, Michelle, Bates, Simon, Batham, Sally, Batista, Ana, Batla, Amit, Batra, Dushyant, Batty, Harry, Batty, Thomas, Batty, Alice, Baum, Miranda, Baumber, Rachel, Bautista, Carina, Bawa, Fareha, Bawa, Tanveer, Bawani, Fatima S, Bax, Simon, Baxter, Matt, Baxter, Nicola, Baxter, Zachary, Bayes, Hannah, Bayo, Lee-Ann, Bazari, Farid, Bazaz, Rohit, Bazli, Ahmad, Beacham, Laura, Beadles, Wendy, Beadon, Kirsten, Beak, Philip, Beale, Andy, Beard, Kathy, Bearpark, Jack, Beasley, Alanna, Beattie, Sandee, Beaumont, Karen, Beaumont-Jewell, Dawn, Beaver, Theresa, Beavis, Sarah, Beazley, Christy, Beck, Sarah, Beckett, Virginia, Beckitt, Rosie, Beckley, Sarah, Beddall, Heidi, Beddows, Seonaid, Beeby, Deborah, Beeby, Sophia, Beech, Gail, Beecroft, Michelle, Beer, Nigel, Beer, Sally, Beety, Jane, Bega, Gabriela, Begg, Alison, Begg, Susan, Beghini, Sara, Begum, Ayesha, Begum, Salman, Begum, Selina, Behan, Teresa, Behrouzi, Roya, Beishon, Jon, Beith, Claire, Belcher, James, Belfield, Holly, Belfield, Katherine, Belgaumkar, Ajay, Bell, Dina, Bell, Gareth, Bell, Gillian, Bell, Jessica, Bell, Lauren, Bell, Louise, Bell, Nicholas, Bell, Pippa, Bell, Stephanie, Bellamu, Jennifer, Bellamy, Mary, Bellamy, Tammy, Bellini, Arianna, Bellis, Amanda, Bellis, Fionn, Bendall, Lesley, Benesh, Naveena, Benetti, Nicola, Benham, Leonie, Benison-Horner, Guy, Benkenstein, Sarah, Benn, Tracey, Bennett, Ann, Bennett, Caroline, Bennett, Denise, Bennett, Gillian, Bennett, Kaytie, Bennett, Kristopher, Bennett, Lorraine, Bennett, Miriam R, Bennett, Sara, Bennion, Karen, Benoy, Gautham, Benson, Vivienne, Bentley, Andrew, Bentley, James, Benton, Ian, Beranova, Eva, Beresford, Matthew, Bergin, Colin, Bergstrom, Malin, Bernatoniene, Jolanta, Berriman, Thomas, Berry, Zoe, Best, Frida, Best, Kimberley, Bester, Ans-Mari, Beuvink, Yvonne, Bevan, Emily, Bevins, Sarah, Bewick, Tom, Bexley, Andrew, Beyatli, Sonay, Beynon, Fenella, Bhadi, Arjun, Bhagani, Sanjay, Bhakta, Shiv, Bhalla, Rekha, Bhandal, Khushpreet, Bhandal, Kulbinder, Bhandari, Ashwin, Bhandari, Lila Nath, Bhandari, Sangam, Bhanich Supapol, Jennifer, Bhanot, Aashutosh, Bhanot, Ravina, Bhasin, Swati, Bhat, Abdul, Bhat, Prashanth, Bhatnagar, Rahul, Bhatt, Karan, Bhayani, Janki, Bhojwani, Deepika, Bhuie, Parminder, Bhuiyan, M S, Bhuiyan, Salimuzzaman, Bibby, Anna, Bibi, Fatima, Bibi, Naheeda, Bibi, Salma, Bicanic, Tihana, Bidgood, Sarah, Bigg, Julie, Biggs, Sarah, Biju, Alphonsa, Bikov, Andras, Billingham, Sophie, Billings, Jessica, Binh, Prof, Binns, Alice, BinRofaie, Muhammad, Bintcliffe, Oliver, Birch, Catherine, Birch, Janine, Birch, Jenny, Birchall, Katherine, Bird, Sam, Bird, Sumedha, Bird, Sarah, Birt, Mark, Bishop, Claire, Bishop, Kilanalei, Bishop, Linda, Bishop, Lisa, Bisnauthsing, Karen, Biswas, Nibedan, Bittaye, Mustapha, Biuk, Sahar, Blachford, Karen, Black, Ethel, Black, Helen, Black, Karen, Black, Mairead, Black, Polly, Black, Virginia, Blackgrove, Hayley, Blackledge, Bethan, Blackler, Joanne, Blackley, Samantha, Blackman, Helen, Blackstock, Caroline, Blair, Cameron, Blakemore, Francesca, Blamey, Helen, Bland, Alison, Blane, Sujata, Blankley, Simon, Blaxill, Parry, Blaylock, Katie, Blazeby, Jane, Blencowe, Natalie, Bloom, Ben, Bloomfield, Jack, Bloss, Angela, Blowers, Alex, Blows, Samuel, Bloxham, Hannah, Blrd, Susan, Blundell, Louise, Blunsum, Andrew, Blunt, Mark, Blunt, Tadhg, Blyth, Ian, Blyth, Kevin, Blythe, Andrew, Blythe, Karen, Boahen, Kwabena Appiah, Boampoaa, Marilyn, Board, Sarah, Bobie, Boniface, Bobruk, Karen, Bodalia, Pritesh N, Bodasing, Neena, Boden, Marianne, Bodenham, Tanya, Boehmer, Gabriele, Boffito, Marta, Bohanan, Katherine, Bohmova, Kristyna, Bohnacker, Niamh, Bokhandi, Sumit, Bokhar, Maria, Bokhari, Saba, Bokhari, Sakina, Bokhari, Syed O, Bokobza, Idan, Boles, Ambrose, Bolger, Clare, Bonaconsa, Candice, Bond, Charlotte, Bond, Helena, Bond, Stuart, Bond, Thomas, Bone, Alice, Boniface, Georgia, Bonney, Joseph, Bonney, Lizzy, Booker, Lauren, Boot, Sarah, Boothroyd, Matthew, Borbone, Joanne, Borman, Naomi, Bosence, Samantha, Bostock, Kirsty, Botting, Neil, Bottrill, Fiona, Bouattia, Hannah, Bough, Laura, Boughton, Hayley, Boult, Zoe, Boumrah, Tarek, Bourke, Miriam, Bourke, Stephen, Bourne, Michelle, Bousfield, Rachel, Boustred, Lucy, Bowes, Alexandra, Bowes, Amy, Bowker, Philip, Bowker, Tabitha, Bowler, Helen, Bowman, Louise, Bowman, Simon, Bowmer, Rachel, Bowring, Angie, Bowyer, Helen, Boyd, Aileen, Boyd, Jenny, Boyd, Laura, Boyer, Nicola, Boyle, Namoi, Boyle, Pauline, Boyle, Rosalind, Boyles, Louise, Brace, Leanna, Bracken, Abbey, Bradder, Jodie, Bradley, Clare J, Bradley, Pamela, Bradley, Patrick, Bradley, Paul, Bradley-Potts, Joanne, Bradshaw, Lynne, Bradshaw, Zena, Brady, Clare, Brady, Rebecca, Brady, Shirin, Braga Sardo, Pedro, Braganza, Denise, Braithwaite, Megan, Brammer, Susan, Branch, Marie, Brankin-Frisby, Thomas, Brannigan, Jamie, Brattan, Sophie, Bray, Fiona, Bray, Nancy, Brazil, Manny, Brear, Lucy, Brear, Tracy, Brearey, Stephen, Bremner, Laura, Brend, Morwenna, Bresges, Carolin, Bressington, Catherine, Bretland, Giovanna, Brewer, Chris, Bridgett, Michael, Bridgwood, Gavin, Brigham, Sara, Bright, John, Brightling, Christopher, Brigstock, Tracey, Brimfield, Lutece, Brinksman, Philip, Brinkworth, Elaine, Brittain-Long, Robin, Britten, Vianne, Britton, Hannah, Broad, Lauren, Broadhead, Sarah, Broadhurst, Rosie, Broadley, Andrew, Broadway, Marie, Brockelsby, Christopher, Brocken, Megan, Brockley, Tomos, Brodsky, Mary, Brogan, Fiona, Brohan, Liz, Brokke, Felicity, Brolly, Jacob, Bromley, David, Brooke-Ball, Hannah, Brooker, Verity, Brookes, Matthew, Brooking, Deirdre, Brooks, Alison, Brooks, Daniel, Brooks, Jolene, Brooks, Karen, Brooks, Nicole, Brooks, Philip, Brooks, Rachel, Brooks, Samuel, Brooks, Sophie, Broom, Malcolm, Broomhead, Natalie, Broughton, Chloe, Broughton, Nathaniel, Brouns, Matt, Brown, Alison, Brown, Ammani, Brown, Andrew, Brown, Ashley, Brown, Caitlin, Brown, Carly, Brown, Catrin, Brown, Ellen, Brown, Heather, Brown, Janet, Brown, Jo, Brown, Louise, Brown, Niall, Brown, Nicola, Brown, Pauline, Brown, Richard, Brown, Robert, Brown, Steven, Brown, Tom, Browne, Bria, Browne, Charlotte, Browne, Duncan, Browne, Mitchell, Brownlee, Stephen, Brraka, Alba, Bruce, Johanna, Bruce, Michelle, Brudlo, Wojciech, Brunchi, Andrei, Brunskill, Nigel, Brunton, Alan, Brunton, Margaret, Bryant, Meera, Bryden, Emma, Brzezicki, Hannah, Buazon, April, Buch, Maya H, Buchan, Ruaridh, Buchanan, Ruaridh, Buche, Danielle, Buck, Amanda, Buck, Lisa, Buckland, Matthew, Buckley, Clare, Buckley, Laura, Buckley, Philip, Buckley, Sarah, Buckman, Carol, Budds, Alex, Bugg, George, Bujazia, Ramadan, Bukhari, Marwan, Bukhari, Shanze, Bulbulia, Richard, Bull, Alex, Bull, Damian, Bull, Kate, Bull, Rhian, Bull, Thomas, Bullock, Emily, Bullock, Susan, Bulteel, Naomi, Bumunarachchi, Kasun, Bungue-Tuble, Roneleeh, Burbidge, Oliver, Burchett, Caroline, Burda, Dorota, Burden, Christy, Burden, Thomas G, Burgess, Mika, Burgess, Richard, Burgess, Sophia, Burhan, Erlina, Burhan, Hasan, Burke, Hannah, Burke, Kerry, Burman, Adrian, Burnard, Sara, Burnett, Caroline, Burnett, Sharon, Burns, Amy, Burns, Collette, Burns, James, Burns, Karen, Burns, Kiki, Burrage, Daniel, Burrows, Kate, Burston, Claire, Burton, Anna, Burton, Ben, Burton, Fiona, Burton, Helen, Burton, Matthew, Butar butar, Mannaria, Butcher, Deborah, Butler, Aaron, Butler, Emily, Butler, Jessica, Butler, Joanne, Butler, Joshua, Butler, Peter, Butler, Susan, Butler, Jenny, Butt, Al-Tahoor, Butt, Massawer, Butt, Mohammad M, Butterworth, Caryl, Butterworth-Cowin, Nicola, Buttery, Robert, Buttle, Tom, Button, Heather, Buttress, Daniel, Bye, Hannah, Byrne, Jane, Byrne, Wendy, Byrne-Watts, Victoria, Cabandugama, Amanda, Cabrero, Luisa, Caddy, Simone, Cade, Ruth, Cadwgan, Anthony, Cahilog, Zhen, Cahyareny, Ajeng, Cairney, Donna, Calderwood, James, Caldow, Darren, Cale, Emily, Calisti, Giorgio, Callaghan, Debbie, Callaghan, Jennifer, Callens, Claire, Callum, Donaldson, Calver, Caroline, Cambell-Kelly, Melissa, Camburn, Tracey, Cameron, David R, Cameron, Eleanor, Cameron, Fraser, Cameron, Sheena, Camm, Christian, Cammack, Renee F D, Campbell, Alison, Campbell, Amy, Campbell, Barbara, Campbell, Bridget, Campbell, Debbie, Campbell, Helen, Campbell, Hilary, Campbell, Jonathan, Campbell, Karen, Campbell, Marion, Campbell, Mark, Campbell, Rachael, Campbell, Robyn, Campbell, Wynny, Campbell Hewson, Quentin, Camsooksai, Julie, Canclini, Lisa, Candido, Shaula M, Candlish, Janie, Caneja, Cielito, Cann, Alexandra, Cann, Johnathon, Cannan, Ruby, Cannon, Abigail, Cannon, Emma, Cannon, Michael, Cannon, Petra, Cannons, Vivienne, Canonizado, Ebnier, Cantliff, Jane, Caplin, Ben, Capocci, Santino, Caponi, Noemi, Capp, Angelika, Capstick, Richard, Capstick, Thomas, Caraenache, Catalin, Card, Aimee, Cardwell, Mary, Carey, Charles, Carey, Rachel, Carley, Simon, Carlin, Ffion, Carlin, Tammy, Carmichael, Samantha, Carmody, Margaret, Carnahan, Mandy, Caroline, Charlotte, Carpenter, Jodi, Carr, Sharon, Carrasco, Anna, Carrington, Zoe, Carroll, Amy, Carroll, Anne, Carroll, Paul, Carson, Rachel, Cart, Cindy, Carter, Emma, Carter, Jonathan, Carter, Michael, Carter, Natasha, Carter, Paul, Carter, Penny, Cartwright, Douglas, Cartwright, Jo-Anne, Carty, Claire, Carty, Lotoyah, Carungcong, Jaime, Carver, Charlotte, Carver, Emma, Carver, Rachel, Casey, Susan, Cassells, Annie, Castiello, Teresa, Castle, Gail, Castles, Bridget, Caswell, Melanie, Catana, Ana Maria, Cate, Heidi, Catelan Zborowski, Anelise, Cathcart, Susanne, Cathie, Katrina, Catibog, Darwin, Catley, Christine, Catlow, Laura, Caudwell, Matthew, Cavazza, Anna, Cave, Ashleigh, Cave, Luke, Cavinato, Simon, Cawa, Frianne, Cawley, Kathryn, Caws, Chloe, Cawthorne, Kay, Cendl, Hankins, Century, Hannah, Cernova, Jeva, Cesay, Mansur, Cetti, Ed, Chabane, Stephanie, Chablani, Manish, Chabo, Cathleen, Chacko, Cyril J, Chadwick, David, Chadwick, Julie, Chadwick, Robert, Chakkarapani, Ela, Chakraborty, Arup, Chakraborty, Mallinath, Chakravorty, Mollika, Chalakova, Petya, Chalise, Bimal Sharma, Chalmers, James, Chalmers, Richard, Chamberlain, Georgina, Chamberlain, Sarah, Chambers, Emma, Chambers, Jonathan, Chambers, Lucy, Chambers, Naomi, Chan, Alex, Chan, Carmen, Chan, Cheuk, Chan, Evelyn, Chan, Jay Marie, Chan, Kawai, Chan, Kayen, Chan, Kimberley, Chan, Ping, Chan, Rebekah (Pui-Ching), Chan, Xin H S, Chandler, Chris, Chandler, Heidi, Chandler, Kim J, Chandler, Stuart, Chandler, Zoe, Chandra, Sumit, Chandran, Navin, Chandrasekaran, Badrinathan, Chang, Yvonne, Chanh, Ho Quang, Chaplin, Grace, Chaplin, Josephine, Chapman, Graeme, Chapman, John, Chapman, Katie, Chapman, Laura, Chapman, Lianne, Chapman, Matthew, Chapman, Polly, Chapman, Timothy, Chappell, Lucy, Charalambou, Amanda, Charles, Bethan, Charlton, Dianne, Charlton, Sam, Chatar, Kevin, Chatha, Calvin, Chatterton, Debra, Chaube, Ritesh, Chaudhary, Muhammad Y N, Chaudhary, Netra B, Chaudhry, Iram, Chaudhry, Zain, Chaudhuri, Nazia, Chaudhury, Muhammad, Chauhan, Anoop, Chauhan, Ruchi S, Chavasse, Alexander, Chavasse, Nicola, Chawla, Vipal, Cheater, Lindsay, Cheaveau, James, Cheeld, Charlotte, Cheeseman, Michelle, Chen, Fang, Chen, Hui Min, Chen, Terence, Cheng, Floria, Cheng, Lok Yin, Cheng, Zhihang, Chenoweth, Helen, Cheong, Chun How, Cherian, Shiney, Cherrie, Mary, Cheshire, Helen, Cheung, Chee Kay, Cheung, Elaine, Cheung, Kayan, Cheung, Michelle, Cheyne, Claire, Chhabra, Swati, Chia, Wei Ling, Chiang, Eric, Chiapparino, Angela, Chicano, Rosavic, Chikungwa, Moses, Chikwanha, Zviedzo A, Chilcott, Gemma, Chilcott, Sam, Chilvers, Alison, Chimbo, Phillipa, Chin, KokWai, Chin, Wen Jie, Chineka, Rumbidzai, Chingale, Amol, Chinonso, Ezomike, Chin-Saad, Chloe, Chirgwin, Margaret, Chisem, Heather, Chisenga, Claire, Chisholm, Catherine, Chisnall, Ben, Chiswick, Carolyn, Chita, Sunder, Chitalia, Nihil, Chiu, Matthew, Chiverton, Laura, Chivima, Brenda, Chmiel, Catherine, Choi, Soha, Choon Kon Yune, Willy, Chopra, Meena, Chopra, Michelle, Choudhary, Vandana, Choudhury, Omur, Choudhury, Sarah, Chow, Bing-Lun, Chowdhury, Mahibbur, Chowdhury, Shahid, Chrisopoulou, Angela, Christenssen, Victoria, Christian, Peter, Christides, Alexander, Christie, Fiona, Christmas, Daniel, Christoforou, Georgios, Christopherson, Thereza, Christou, Anna, Christy, Mark, Chrysostomou, Paris, Chua, Yunli, Chudgar, Dip, Chudleigh, Richard, Chukkambotla, Srikanth, Chukwu, Michael E, Chukwulobelu, Izu, Chung, Chi Yee, Church, Elaine, Church, Sara R, Churchill, David, Cianci, Nicole, Cicconi, Paola, Cinardo, Paola, Cipinova, Zdenka, Cipriano, Bessie, Clamp, Sarah, Clancy, Bridget, Clapham, Melanie, Clare, Edel, Clare, Sarbjit, Clark, Andrew, Clark, Charlotte, Clark, Diane, Clark, Emma, Clark, Felicity, Clark, Gabrielle, Clark, James, Clark, Julia, Clark, Katherine, Clark, Kaylea, Clark, Louise, Clark, Lucy, Clark, Martyn, Clark, Matthew, Clark, Nicola, Clark, Patricia, Clark, Richard, Clark, Thomas, Clark, Tonia, Clark, Zoe, Clarke, Alison, Clarke, Andrea, Clarke, Jude, Clarke, Paul, Clarke, Robert, Clarke, Roseanne, Clarke, Samantha, Clarke, Sheron, Claxton, Alleyna, Claxton, Louis, Clay, Kate, Clayton, Catherine, Clayton, Elizabeth, Clayton, Olivia, Clayton-Smith, Jill, Clearyb, Bethan, Cleaver, Chris, Cleeton, Rose, Clement, Ian, Clemente de la Torre, Carlota, Clements, Jayne, Clements, Suzanne, Clenton, Sue, Cliff, Sheryl, Clifford, Rachael, Clifford, Sarah, Clive, Amelia, Clouston, Jonathan, Clubb, Vincent, Clueit, Samantha, Clutterbuck, Lisa, Clyne, Andrea, Coakley, Michelle, Coakley, Peter G L, Cobain, Kathryn, Cochrane, Alexandra, Cochrane, Patricia, Cockayne, Laura, Cockerell, Maeve, Cockerill, Helen, Cocks, Shirley, Codling, Rachel, Coe, Adam, Coetzee, Samantha, Coey, David, Cohen, Danielle, Cohen, Jonathan, Cohen, Oliver, Cohen, David, Cohn, Mike, Coke, Louise, Coker, Olutoyin, Colbeck, Nicholas, Colbert, Roghan, Cole, Esther, Cole, Jade, Cole, Joby, Coleman, Garry, Coleman, Matt, Coleman, Nick, Coles, Holly, Colin, Macleod, Colino-Acevedo, Alicia, Colley, Julie, Collie, Kathleen, Collier, Alexandra, Collier, Danielle, Collier, Dawn, Collier, Heather, Collingwood, Terry, Collini, Paul, Collins, Emma, Collins, Jaimie, Collins, Joanne, Collins, Kayleigh, Collins, Megan, Collins, Nicola, Collins, Sally, Collins, Vicky, Collinson, Andrew, Collinson, Bernadette, Collinson, Jennifer, Collis, Matthew, Colmar, Madeleine, Colton, Hayley E, Colton, James, Colville, Katie, Colvin, Carolyn, Combes, Edward, Comer, David, Comerford, Alison, Concannon, Dónal, Condliffe, Alison, Condliffe, Robin, Connell, Emma, Connell, Lynne, Connell, Natalie, Connelly, Karen, Connolly, Gavin, Connor, Emma, Conroy, Antonia, Conroy, Kevin, Conteh, Veronica, Convery, Rory, Conway, Francesca, Conway, Grainne, Conway, Rhiannon, Conway, Robert, Conyngham, Jo-Anna, Cook, Amanda, Cook, Amber, Cook, Colette, Cook, Eloise, Cook, Gemma, Cook, Helen, Cook, Julie, Cook, Martin, Cook, Sarah, Cooke, Danielle, Cooke, Graham, Cooke, Hannah, Cooke, Justin, Cooke, Katrina, Cooke, Tim, Cooke, Vikki, Cooper, Adele, Cooper, Chris, Cooper, David, Cooper, Helen, Cooper, Jamie, Cooper, Lauren, Cooper, Nick, Cooper, Rowena, Cooray, Samantha, Cope, Thomas, Corbet, Sinead, Corbett, Carolyn, Corbishley, Ailsa, Corcoran, John, Cordell, Chris, Cordle, Jessica, Corfield, Alasdair, Corless, John, Corlett, Alison, Cornwell, Joe, Cornwell, Michael, Corogeanu, Diana, Corr, Aisling, Corredera, Mirella, Corrigan, Ruth, Corry, P, Corser, Rita, Cort, Jon, Cosgrove, Denise, Cosier, Tracey, Costa, Patricia, Costa, Telma, Coston, Charlie, Cotgrove, Susannah, Coton, Zoe, Cottam, Lisa-Jayne, Cotter, Rhiannon, Cotterill, Donna, Cotton, Caroline, Couch, George, Coulding, Martina, Coull, Andrew, Counsell, David, Counter, David, Coupland, Cherry, Courtney, Ellie, Courtney, Julia, Cousins, Rebecca, Coutts, Amanda J, Cowan, Alexander, Cowan, Elena, Cowan, Richard, Cowell, Richard, Cowen, Louise, Cowman, Steve, Cowton, Amanda, Cox, Ellie, Cox, Emma, Cox, Giles, Cox, Helen, Cox, Karina, Cox, Miriam, Coy, Karen, Cradduck-Bamford, Andrea, Craig, Hannah, Craig, Jayne, Craig, John, Craig, Victoria, Craighead, Felicity, Cramp, Matthew, Cranston, Hayley, Crasta, Sheetal S, Crause, Jacolene, Crawford, Angie, Crawford, Emma, Crawford, Isobel, Crawshaw, Sarah, Creagh-Brown, Ben, Creamer, Andrew, Creaser-Myers, Amanda, Cremona, Joanne, Cremona, Saveria, Crepet, Anna, Cresswell, Janet, Cribb, Mark, Crichton, Charles, Crilly, Declan, Crisp, Lauren, Crisp, Nikki, Crocombe, Dominic, Croft, Maria, Crooks, Jennifer, Crosby, Harriet, Cross, Elizabeth, Cross, Tim, Crothers, Amy, Crotty, Stephen, Crouch, Susan, Crow, Madeleine, Crowder, Amanda, Crowley, Kate, Crowley, Teresa, Croysdill, Rebecca, Cruickshank, Callum, Cruickshank, Conor, Cruickshank, Irena, Cruise, James, Cruz, Carina, Cruz Cervera, Trino, Cryans, Dominic, Cui, Guanguo, Cui, Helen, Cullen, Lorraine, Cummings-Fosong, Gillian, Cunliffe, Victoria, Cunningham, Neil, Cunningham, Nicola, Cupitt, Jason, Curgenven, Hollie, Curnow, Gerens, Curran, David, Curran, Simon, Currie, Craig, Currie, Jacqueline, Currie, Scarlett, Currie, Susan, Currie, Susie, Curtis, Jonathan, Curtis, Katrina, Curtis, Matthew, Curtis, Olivia, Curtis, Thomas, Cuthbertson, Rebecca, Cuthill, Jennifer, Cutler, Sean, Cutts, Sarah, Czekaj, Marta, Czylok, Patrycja, D'Souza, Shane, da Rocha, Joana, Dafalla, Mohammed, Dagens, Andrew, Daggett, Helen, Daglish, Jacqui, Dahiya, Sandeep, Dale, Anne, Dale, Katie, Dale, Michaela, Dale, Sam, Dale, Susan, Dales, Jolyon, D'Alessandro, Umberto, Dalgleish, Helen, Dallow, Helen, D'aloia, Carlo, Dalton, Dermot, Dalton, Morag, Daly, Zoe, Damani, Mansi, Damm, Eleanor, Danga, Akila, Dangerfield, Joanne, Daniel, Amelia, Daniel, Priya, Daniels, Allison, Dann, Adela, Danso, Kwaku Gyasi, Danso-Bamfo, Sandra, Dao, Quang Tung, Darby, Suzanne, Darbyshire, Alex, Darbyshire, Janet, Dargan, Paul, Dark, Paul, Darlington, Kate, Darnell, Sarah, Darton, Thomas, Darylile, Guledew, Das, Avisnata, Das, Manjusha, Das, Sukamal, Daschel, Martin, Dasgin, Joanne, Datta, Dibyendu, Daunt, Anna, Dave, Vaishali, Davenport, Emily, Davey, Mark, Davey, Miriam, Davey, Molly, David, Mini, Davidson, Alexander, Davidson, Laura, Davidson, Neil, Davidson, Richard, Davies, Albert, Davies, Alison, Davies, Amanda, Davies, Amy, Davies, Angela, Davies, Bethan, Davies, Caroline, Davies, Carolyn, Davies, Catrin, Davies, Dawn, Davies, Drew, Davies, Elaine, Davies, Elinor, Davies, Ellie, Davies, Ffyon, Davies, Gwyneth, Davies, Helen, Davies, Jennifer, Davies, Jim, Davies, Karen, Davies, Kelly, Davies, Kim, Davies, Llinos, Davies, Louisa, Davies, Matthew, Davies, Michelle, Davies, Nina, Davies, Owen, Davies, Patrick, Davies, Rachel, Davies, Rhys, Davies, Ruth, Davies, Sally, Davies, Sarah, Davies, Simon, Davies, Sue, Davis, Alison, Davis, Julie-Ann, Davis, Katherine, Davis, Peter, Davis-Cook, Andrea, Davison, Alexander, Dawe, Christine, Dawe, H, Dawkins, Mark, Dawson, Angela, Dawson, Danielle, Dawson, Elizabeth, Dawson, Joy, Dawson, Lucinda, Dawson, Mike, Dawson, Susan, Dawson, Tom, Dawson, Isla, Daxter, Andrew, Day, Andrew, Day, Jacob, Day, Jeremy N, D'Costa, Jamie, De, Parijat, De, Pradip, de Fonseka, Duneesha, de Freitas, Toni, De Los Santos Dominguez, Pamela, De Pretto, Roberta, De Santana Miranda, Frederico, de Sausmarez, Eleanor, de Silva, Shanika, de Silva, Thushan, De Sousa, Jessica, De Sousa, Paulo, de Souza, James, De Souza, Phillip, De Soyza, Anthony, de Vere, Natasha, de Vos, Johannes, Deacon, Bethan, Dealing, Sharon, Dean, Anna, Dean, Julie, Dean, Katrina, Dean, Stephen, Dean, Tessa, Deane, Jill, Dear, James, Dearden, Effie, Deas, Catherine, Debbie, Samuel, Debreceni, Gabor, Deelchand, Vashist, Deeley, Matthew, Deery, Joanne, Defever, Emmanuel, Del Forno, Manuela, Dela Rosa, Arnold, De-La-Cedra, Gonzalo, Dell, Amanda, Demetriou, Carrie, DeMets, David, Democratis, Jane, Denham, Jacqueline, Denis, Emmanuelle, Denley, Laura, Denmade, Craig, Dent, Alexandra, Dent, Kathy, Dent, Martin, Denton, Elise, Denwood, Tom, Deole, Nishigandh, Depala, Darshita, Depante, Maria, Dermody, Susan, Desai, Amisha, Desai, Asmita, Desai, Purav, Deshpande, Sanjeev, Deshpande, Vai, Devkota, Sirjana, Devkota, Usha, Devonport, Debbie, Devonport, Matthew, Dey, Prakash, Dey, Vishal, Deylami, Rogin, Dhaliwal, Kevin, Dhani, Sundip, Dhanoa, Amandeep, Dhar, Mili, Dhariwal, Ankush, Dharmasena, Dawpadee, Dhasmana, Devesh, Dhillon, Ekanjali, Dhillon, Reiss, Dhillon, Syra, Dhimal, Meghnath, Dhiru, Dipali, Dhorajiwala, Trupti, Dias, Priya, Diaz, Stephanie, Diaz-Pratt, Kayleigh, Dibas, Mohammed, Dickerson, Debbie, Dicks, Pamela, Dickson, Matt, Dickson, Stuart, Digby, J, Digpal, Ronneil, Dillane, Sean, Diment, Sarah, Dimitri, Paul, Dimitriadis, Georgios, Din, Sajeel, Dinh, Thai H, Dinh, Thi T T, Dipper, Alex, Dipro, Sabiq, Dirmantaite, Laura, Dismore, Lorelle, Ditchfield, Lisa, Diver, Sarah, Diwakar, Lavanya, Diwan, Preeti, Dixon, Caroline, Dixon, Giles, Dixon, Kate, Djeugam, Brice, Dlamini, Sipho, Dlouhy, Petr, D'Mello, Andrea, Dmitri, Paul, Do, Thi Tien, Dobbie, Laurence, Dobranszky Oroian, Marinela, Dobson, Charlotte, Dobson, Lee, Docherty, Marie, Dockrell, David, Dodd, Jacqueline, Dodd, James, Dodds, Jackie, Dodds, Rebecca, Dodds, Steve, Dogra, Richi, Doherty, Conor, Doherty, Erin, Doherty, Warren, Doi, Yumiko, Doig, Iain, Doke, Eleanor, Dolan, Daniel, Dolman, Mark, Dolman, Rozzie, Donald, Lisa, Donald, Katie, Donaldson, Callum, Donaldson, Christopher, Donaldson, Denise, Donaldson, Gillian, Donaldson, Kate, Dong, Phu Khiem, Donkor, Martha, Donlon, Sinead, Donnachie, Joanne, Donnelly, Eilish, Donnelly, Ronan, Donnison, Phil, Donohoe, Aravindhan, Donohoe, Gemma, Donohue, Bryan, Dooks, Emma, Doonan, Reece J, Van Doorn, Rogier, Doran, Grainne, Dore, Rachael, Dorey, Kane, Dorgan, Sharon, Dos Santos, Kataryna, Dosani, Moonira, Dosanjh, Davinder, Dospinescu, Paula, Doss, Isabelle, Doudouliaki, Theonymfi, Dougherty, Andrew, Doughty, Jill, Douglas, Katie, Douse, Jonathan, Dow, Allyn, Dowden, Lucy, Dower, Michelle, Dowling, Sud, Downer, Nicola, Downes, Charlotte, Downes, Rob, Downes, Thomas, Downey, Damian, Downey, Robert, Downing, Caroline, Downs, Louise, Dowson, Simon, Dragan, Cornel, Dragos, Cristina, Drain, Maire, Drake, Chelsea, Drew, Victoria, Drewett, Olivia, Drexel, Anthony, Driscoll, Celine, Drogan, Helena, Drosos, Odysseas, Drummond, Graham, Drury, Katie, Druryk, Kay, Druyeh, Ronald, Dryburgh-Jones, Jack, Drysdale, Simon, Du Thinh, An, Dube, Hazel, Dube, Judith, Duberley, Stephen, Duckenfield, Paige K, Duckles-Leech, Hayley, Duff, Nicola, Duffield, Emma, Duffy, Heather, Duffy, Helen, Duffy, Katharine, Dufour, Lionel, Duggan, Annette, Dugh, Parveen, Duhoky, Rauand, Duignan, Janice, Dulay, Jennifer, Dummer, Simon, Duncan, Alexis, Duncan, Andrew, Duncan, Christopher, Duncan, Fullerton, Duncan, Gregory, Duncan, Holly, Duncan, Robert, Dundas, Stephanie, Van Dung, Do, Dunleavy, Aileen, Dunleavy, Julia, Dunn, Alessia, Dunn, Charlotte, Dunn, Damian, Dunn, Laura, Dunn, Paul, Dunne, Charlene, Dunne, Karen, Dunning, Fiona, Dunphy, Aidan, Duong, Tran Thi Hai, Duraiswamy, Venkat, Duran, Beatriz, DuRand, Ingrid, Durdle, Leanne, Duric, Natalie, Durie, Alison, Durie, Emily, Durogbola, Samuel, Durojaiye, Chris, Durrans, Laura, Durrant, Katie, Durrington, Hannah, Duru, Iheukwumere, Duvnjak, Haris, Dwarakanath, Akshay, Dwarakanath, Laasya, Dwomoh Nkrumah, Dennis, Dwyer, Ellen, Dyar, Zara, Dyball, Claudia, Dyer, Kristyn, Dymond, Harvey, Dymond, Tom, Eades, Chris, Eadie, Lauren, Eadie, Rebekah, Eagles, Laura, Eapen, Beena, Earl, Naomi, Early, Joanne, Earwaker, Melissa, Easom, Nicholas, East, Clare, Easthope, Amy, Easton, Fraser, Easton, Jack, Easton, Patrick, Eatough, Ruth, Ebigbola, Oluwadamilola, Ebon, Martin, Eccles, Alison, Eccles, Sinan, Eddings, Chloe, Eddleston, Michael, Edgar, Maureen, Edgerley, Katharine, Edmond, Nicholas, Edmondson, Mary, Edmunds, Tracy, Edwards, Abby, Edwards, Alexandra, Edwards, Catherine, Edwards, Joy, Edwards, Kennedy, Edwards, Mandy, Edwards, Martin, Edwards, Sophie, Eedle, Jenny, Eggink, Aline, Egginton, Dawn, Eggleston, Sam, Ehiorobo, Loveth, Eisen, Sarah, Ekeowa, Ugochukwu, Ekoi, Mohamed, Ekunola, Ayomide, El Behery, Soha, Elashhar, Nagla, Elawamy, Lisa, Elbeshy, Mohamed, El-Bouzidi, Kate, Elder, Jennifer, El-Din, Mohammed, Eldridge, Emma, Eleanor, Diana, Elenwa, Uchenna, Eletu, Ibrahim, Elfar, Eman, Elgamal, Mayy Magdy, Elgohary, Amr, Elhadi, Mohamed A A, Elia, Stellios, Elias, Jennifer, Elias, Tania, Elkaram, Nadia, Elkins, Andrew V, Ellam, Julie, Ellard, Nikki, Ellerton, Laura N, Elliot, Lucy, Elliott, Amy, Elliott, Fiona, Elliott, Kerry, Elliott, Scott, Elliott, Sian, Ellis, Annie, Ellis, Christine, Ellis, Kaytie, Ellis, Leila, Ellis, Rupert, Ellis, Tak-Yan, Ellis, Yvette, Ellwood, Alison C, Elmahdi, Rahma, Elmahi, Einas, Elmasry, Hannah-May, El-Naggar, Mohammed, Elndari, Najla, Elneima, Omer, Elokl, Mohamed, Elradi, Ahmed, Elsaadany, Mohamed, Elsayed, Mohammed A S A, El-Sayeh, Sally, El-Sbahi, Hana, Elsebaei, Mohammad, Elsefi, Tarek, El-Shakankery, Karim, Elsheikh, Alguili, El-Taweel, Hosni, Elyoussfi, Sarah, Emberey, Jonathan, Emberson, Jonathan R, Emberton, John, Emery, Anna, Emmanuel, Julian, Emmerson, Ingrid, Emms, Michael, Emond, Florence, Emonts, Marieke, Enachi, Nicu, Enenche, Dickson, Engden, Angila, English, Katy, Entwistle, Emma, Enyi, Hene, Erotocritou, Marios, Eskander, Peter, Esmail, Hanif, Essa, Fatheha, Evans, Brynach, Evans, Chris, Evans, Debra, Evans, E, Evans, Emrys, Evans, Gail, Evans, Gareth, Evans, Isabel, Evans, Jack, Evans, Jacqueline, Evans, Jennifer, Evans, John, Evans, Jolanta, Evans, Lisa, Evans, Lynn, Evans, Mim, Evans, Morgan, Evans, Ranoromanana, Evans, Sharon, Evans, Sian, Evans, Teriann, Evans, Tomos, Everden, Caroline, Everden, Serenydd, Every, Lynette, Evison, Hayley, Evison, Lynsey, Ezenduka, Chiamaka, Faccenda, Jacqueline, Fahel, Leila, Fahmay, Youstina, Fairbairn, Ian, Fairbairn, Sara, Fairbairn, Terry, Fairclough, Andy, Fairlie, Louise, Fairweather, Mark, Fajardo, Anne, Falcone, Naomi, Falconer, Euan, Fallon, John, Fallow, Andrea, Faluyi, David, Fancois, Victoria, Farah, Ayaan, Farah, Muna, Farah, Qayyum, Fard, Nowin Z, Fares, Leila, Farg, Amr, Farmer, Adam, Farmer, Katie, Farmery, Toni, Farnworth, Samantha, Farook, Faiyaz, Farooq, Hadia, Farooq, Sidrah, Farquhar, Fiona, Farr, Holly, Farrell, Aaron, Farrell, Barbara, Farrukh, Fayed, Farthing, James, Farzana, Syeda, Fasina, Rahmatu, Fatemi, Azam, Fatemi, Mina, Fathima, Suman, Fatimah, Nibah, Faulkner, Maria, Faust, Saul N, Favager, Clair, Fawke, Joe, Fawohunre, Sinmidele, Fazal, Abul, Fazleen, Aisthath, Fearby, Simon, Fearnley, Connie, Feben, Alex, Fedel, Federico, Fedorova, Daria, Fegan, Christopher, Felongo, Mae, Felton, Lynsey, Felton, Tim, Fenlon, Kate, Fenn, Andrea, Fennelly, Ruth, Fenner, Isabelle, Fenton, Ciara, Fenton, Melisa, Ferenando, Gloria, Ferguson, Cameron, Ferguson, Jenny, Ferguson, Kathryn, Ferguson, Katie, Ferguson, Susan, Ferguson, Susie, Ferguson, Victoria, Fernandes, Denzil, Fernandez, Candida, Fernandez, Eduardo, Fernandez, Maria, Fernandez Lopez, Sonia, Fernandez Roman, Jaime, Fernando, Callum J, Fernando, Jessica, Feroz, Ahmed, Ferranti, Pietro, Ferrari, Thais, Ferrelly, Eleanor, Ferrera, Alexandra, Ferriman, Emma, Ferron, Sheldon, Fethers, Nicholas, Field, Ben, Field, Janet, Field, Rebecca, Fielder, Karen, Fieldhouse, Lindsey, Fielding, Andra, Fielding, Julie, Fielding, Sarah, Fikree, Asma, Filipa, Santos, Filson, Sarah A, Finan, Shona, Finbow, Sarah, Finch, Deborah J, Finch, Joanne, Finch, Laurie, Finch, Simon, Finch, Spencer, Fineman, Natalie, Finlayson, Jim, Finlayson, Lauren, Finn, Adam, Finn, Joanne, Finnerty, Dylan, Finney, Clare, Finucane, Deborah, Fiouni, Sofia, Fiquet, Jo, Firi, Promise, Fisher, James, Fisher, Neil, Fishman, Daniel, Fishwick, Krystofer, Fitton, Carolyn, Fitzgerald, Felicity, Fitzgerald, Fiona, Fitzjohn, Karen, Flaherty, Jan, Flanagan, Michael, Flanders, Charles, Flaris, Nikolaos, Fleming, Gail, Fleming, Julie, Fleming, Lucy, Fleming, Paul, Flesher, William, Fletcher, Alison, Fletcher, Anna, Fletcher, Jonathan, Fletcher, Lucy, Fletcher, Simon, Fletcher, Sophie, Flett, Fiona, Flewitt, Karen, Flockhart, Sarah, Flood, Christopher, Floodgate, Ian, Flor, Jonathan, Florence, Vincent, Flowerdew, Mary, Floyd, Sharon, Flynn, Margaret J, Flynn, Rachel, Foden, Claire, Fofana, Adama, Fogarty, Georgina, Foley, Paul, Folkes, Linda, Fong, Tracey, Font, Daniela M, Foo, Aiwyne, Foo, Jane, Foot, Andrew, Foot, Helen R, Foot, Jayne, Forbes, Jane, Ford, Amber, Ford, Jamie, Fordham, Imogen, Foreman, Jennifer, Forester, Matthew, Forkan, Mohammad, Fornolles, Caroline, Forrest, Adam, Forsey, Ellie, Forsey, Miranda, Forshall, Thomas, Forster, Elliot, Forsyth, Abigail, Forton, Julian, Foster, Conrad, Foster, Emily, Foster, Joseph, Foster, Rachel A, Foster, Tracy, Foulds, Angela, Foulds, Ian, Fowe, Folakemi, Fowkes, Natasha, Fowler, Emily, Fowler, Robert, Fowler, Stephen, Fox, Amy, Fox, Claire, Fox, Heather, Fox, Jonathan, Fox, Laura, Fox, Lauren, Fox, Natalie, Fox, Olivia, Fox, Simon, Foxton, Sarah-Jane, Fraile, Eva, Frake, Rebecca, Francioni, Alex, Francis, Olesya, Francis, Rebecca, Francis, Sarah, Francis-Bacon, Theodora, Frankland, Helen, Franklin, Jessica, Franklin, Siobhan, Fraser, Catherine, Fratila, Andi, Frayling, Sharon, Fredlund, Martyn, Freeman, Anna, Freeman, Carol, Freeman, Elaine, Freeman, Hannah, Freeman, Nicola, Freer, Clare, French, Eleanor, French, Thomas, Freshwater, Karen, Frise, Matthew, Fromson, Renate, Frosh, Adam, Frost, John, Frost, Victoria, Froud, Oliver, Frowd, Rachel, Fryatt, Arun, Frygier, Andrzej, Fuller, Bridget, Fuller, Liz, Fuller, Lucy, Fuller, Tracy, Fullerton, Duncan, Fung, Carrie, Fung, Gayle, Funnell, Sarah, Furness, John, Fyfe, Andrew, G, Nytianandan, Gabbitas, Elizabeth, Gabriel, Claire, Gabriel, Zoë, Gachi, Hadiza, Gaffarena, Sophie, Gage, Sarah, Gahir, Joshua, Gajebasia, Sarveen, Gajewska-Knapik, Katarzyna, Gajmer, Babita, Galani, Zacharoula, Gale, Christopher, Gale, Hugo, Gale, Linda, Gale, Rebecca, Gali, Swetha, Gallagher, Bernadette, Gallagher, Jude, Gallagher, Rosie, Gallagher, William, Gallam, Feroze, Galliford, Joanne, Galloway, Catherine, Galloway, Chris, Galloway, Emma, Galloway, Jacqui, Galloway, James, Galvin, Anna, Galvis, Victoria, Gamble, Gareth, Gamble, Laura, Gamble, Liz, Gammon, Brian, Gan, Chien N, Ganaie, Muhammad B, Ganapathi, Jaikumar, Ganapathy, Ramesh, Gandhi, Kaminiben, Gandhi, Sarah, Ganesh, Usha, Ganeshanathan, Thenugan, Ganguly, Saibal, Gani, Abrar, Ganley, Pauline, Garcia, Ukraina, Garden, Emma-James, Gardener, Antoni D, Gardiner, Emma, Gardiner, Michael, Gardiner, Phil, Gardiner, Siobhan, Gardiner-Hill, Caroline, Gardner, Jonathan, Gardner, Louis, Garfield, Mark, Garg, Atul, Garg, Isha, Garlick, Nathan, Garner, Daniel, Garner, Justin, Garner, Lucie, Garner, Zoe, Garr, Rosaline, Garrero, Kathryn A, Gartaula, Manisha, Garty, Florence, Gascoyne, Rachel, Gashau, Hyeriju, Gatenby, Aoife, Gaughan, Erin, Gaurav, Alok, Gavrila, Mariana, Gaylard, Jane, Gayle, Sophie, Geddie, Catherine, Gedge, Ian, Gee, Sarah, Geele, Fartuun, Geerthan, Kalaichelvi, Gellamucho, Minnie, Gelly, Karzan, Gelmon, Leila, Gelves-Zapata, Sandra, Genato, Gemma, Gent, Neal, Gent, Susan, Geoghegan, Natalie, George, Aparna, George, Bini, George, Sam, George, Susan, George, Tina, George, Valerie P, Georges, Simon, Georgiou, Domonique, Gerard, Peter, Gerdes, Leigh, Germain, Louise, Gerrish, Helen, Getachew, Abel, Gethin, Louise, Gettings, Siobhan, Ghanayem, Hisham, Ghavami Kia, Bijan, Ghazal, Shaista, Gherman, Anca, Ghosh, Alison, Ghosh, Dipansu, Ghosh, Justin, Ghosh, Subhamay, Giannopoulou, Sarra, Gibani, Malick, Gibb, Chris, Gibbison, Ben, Gibbons, Kerry, Gibson, Alex, Gibson, Bethan, Gibson, Jamie, Gibson, Kimberley, Gibson, Kirsty, Gibson, Sian, Gigi, Mary, Gilbert, Cat, Gilbert, Jeanette, Gilbert, Kayleigh, Giles, Benjamin, Gilham, James, Gill, Mandy, Gill, Lynne, Gillen, Paul, Gillesen, Annelies, Gillespie, Katherine, Gillham, Elizabeth, Gillian, Andrew, Gilliland, Deborah, Gillott, Robert, Gilmour, Danielle, Gilmour, Kate, Gilmour, Lesley, Ginn, Louis, Ginting, Franciscus, Giokanini-Royal, Theodora, Gipson, Anna, Giri, Barbie, Girling, Joanna, Gisby, Rhian, Gkioni, Angelena, Gkoritsa, Aikaterini, Gkrania-Klotsas, Effrossyni, Gladwell, Amy, Glanville, James, Glasgow, Jessica, Glasgow, Susannah, Glass, Jon, Glass, Lynn, Glaysher, Sharon, Gledhill, Lisa, Glenday, Eleanor, Glennon, Ana, Glossop, Jodie, Glover, John, Glover, Kyle, Glover, Michelle, Glover Bengtsson, Jan, Glowski, Deborah, Glynn, Sharon, Gnanalingam, Chevanthy, Goddard, Julie, Goddard, Wendy, Godden, Emily, Godden, Jo, Godlee, Sarah, Godson, Emma, Godwin, Gillian, Gogoi, Sukanya, Goh, Aiky, Gohel, Manjinder, Goiriz, Rebeca, Gokaraju, Sriya, Goldacre, Raphael, Goldsmith, Arthur, Goldsmith, Portia, Gomersall, Darren, Gomez, Lucia, Gomez-Marcos, Raquel, Gondal, Ali, Gonzalez, Celia, Goodall, Jack, Goodall, Vicky, Goodenough, Bob, Goodfellow, Anna, Goodfellow, Laura, Goodlife, James, Goodwin, Camelia, Goodwin, Elizabeth, Goodwin, Jayne, Goodyear, Paula, Gooentilleke, Rajiv, Goonasekara, Michelle, Gooseman, Sheila, Gopal, Shameer, Gordon, Chris, Gordon, Sally, Gore, Robin, Gorick, Hugh, Gorman, Caitlin, Gorman, Claire, Gormely, Stuart, Gorniok, Maria, Gorog, Diana, Gorst, Michelle, Gorsuch, Thomas, Gosai, Jayshreebahen, Gosling, Rebecca, Gosling, Sally, Gosney, Georgina, Goss, Vanessa, Gotham, Dzintars, Gott, Naomi, Goudie, Elizabeth, Gould, Nicole, Gould, Susan, Goumalatsou, Charlotte, Gourbault, Lysander, Govind, Abha, Govindan, Rajesh, Gowans, Sharon, Gowda, Girish, Gowda, Rohit, Gower, Hannah, Goyal, Pankaj, Goyal, Sunil, Goyal, Sushant, Graham, Cheryl, Graham, Clive, Graham, Jonathan, Graham, Justin, Graham, Libby, Graham, Rachel, Graham, Sharon, Graham-Brown, Matthew, Grahamslaw, Julia, Grana, Gianluca, Grandison, Tracyanne, Grandjean, Louis, Grant, Alison, Grant, Ann, Grant, David, Grant, Kirstie, Grant, Matthew, Grant, Pauleen, Gravell, Rhys, Graves, Jenny, Gray, Alasdair, Gray, Catherine, Gray, Georgina, Gray, Glaxy, Gray, Jackie, Gray, Karen, Gray, Nicola, Gray, Roxanne, Gray, Sebastian, Grayson, Alan, Greaves, Fiona, Greaves, Paul, Green, Alastair, Green, Amy, Green, Amy S, Green, Charlotte, Green, Christopher A, Green, David, Green, Frederick, Green, Joel, Green, Marie, Green, Nicola, Green, Stacey, Greene, Diarra, Greenfield, Philippa, Greenhalgh, Alan, Greenwood, Daniel, Greer, Sandra, Gregory, James, Gregory, Jane, Gregory, Katie, Gregory, Tamsin, Greig, Jill, Greig, Julia, Grenfell, Rebecca, Grenier, Teena, Grenville, Jack, Gresty, Jo, Grevatt, Susan, Grey, Glaxy, Gribben, Samuel, Gribbin, Andrew, Gribble, Amy, Grieg, Natasha, Grieve, Douglas, Griffin, Ben, Griffin, Denise, Griffin, Mel, Griffith, Sian, Griffiths, Andrew, Griffiths, Daniel, Griffiths, David, Griffiths, Donna, Griffiths, Isabel, Griffiths, Mark, Griffiths, Nicola, Griffiths, Oliver, Griffiths, Sandra, Griffiths, Sarah, Griffiths, Scott, Griffiths, Yvonne, Grigoriadou, Sofia, Grigsby, Steph, Grist, Paul, Grobovaite, Evelina, Grogono, Dorothy, Grondin, Clarissa, Groome, Rachel, Grose, Pauline, Grosu, Liliana, Grounds, Jenny, Grout, Margaret, Grover, Helen, Groves, Jayne, Grubb, Neil, Grundy, Julie, Guarino, Francesca, Gudur, Sharada, Guerin, Jacinta, Guettari, Sharazeq, Gulati, Shivang, Gulia, Vikas, Gunasekara, Harsha, Gunasekera, Pumali, Gunawardena, Malin, Gunganah, Kirun, Gunn, Jessica, Gunter, Emma, Gupta, Anup Kumar, Gupta, Alok, Gupta, Atul, Gupta, 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Elizabeth, Hall, Fiona, Hall, Helen, Hall, Jennifer, Hall, Kathryn, Hall, Laura, Hallas, Jan, Hallas, Kyle, Hallett, Charles, Halliday, Jackie, Hallman, Akmal, Halls, Heather, Hamdollah-Zadeh, Maryam, Hamed-Adekale, Ifedadepo A, Hameed, Bilal, Hameed, Mohammed, Hamers, Raph L, Hamid, Imran, Hamie, Mohamad, Hamill, Raymond, Hamilton, Bethany, Hamilton, Fergus, Hamilton, Gus, Hamilton, Leigh, Hamilton, Melanie, Hamilton, Nicola, Hamilton, Sara, Hamlin, Ruth, Hamlyn, Eleanor, Hammans, Beatrice, Hammersley, Shirley, Hammerton, Kate, Hammond, Bev, Hammond, Emily, Hammond, Leah, Hammond, Sally, Hammonds, Fiona, Hamoodi, Ibrahim, Hampshire, Karen, Hampson, James A, Hampson, Jude, Hampson, Lucy, Hamzah, Lisa, Han, Jenny, Hanci, Ozan, Hand, Sadiyah, Handayani, Lala, Handford, Jasmine, Handrean, Soran, Handzewniak, Nina K, Haney, Sarah, Hang, Vu Thi Kim, Hanif, Sheharyar, Hanison, E, Hanison, Esther, Hannah, Jennifer, Hannington, Amy, Hannun, Merhej, Hanrath, Aidan, Hanratty, Helena, Hansen, 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Muhammad, Hussain, Reda, Hussain, Rizwana, Hussain, Samia, Hussain, Sanniah, Hussain, Yasmin, Hussam El-Din, Mohammed, Hussein, Samahir F E M, Hussein, Ziad, Hussey, Rebecca, Hussien, Adiel Haqiq, Hutchinson, Anja, Hutchinson, Camille, Hutchinson, Dorothy, Hutchinson, Elizabeth, Hutchinson, John, Hutsby, Claire, Hutton, Paula, Huy, Nguyen Quang, Huyen, Thuong, Huyen, Tran Bang, Huyen Thuong, Nguyen Thi, Huynh, Hieu, Hydes, Daniella, Hyde-Wyatt, Jamie, Hynes, Niamh, Hyslop, Megan, Iakovou, Angeliki, Ibison, Katherine, Ibraheim, Mazen, Ibrahim, Abdalla, Ibrahim, Ahmed, Ibrahim, Asil, Ibrahim, Javed, Ibrahim, Mamoun, Ibrahim, Mohamed, Ibrahim, Wadah, Icke, Becky, Idowu, Adetokunbo Idowu, Idrees, Muhammad, Idrees, Nauman, Iftikhar, Hina, Iftikhar, Mawara, Igwe, Chukwuemeka, Igwe, Ogechukwu, Ijaz, Mohammad, Ikomi, Amaju, Iles, Clare, Iliodromiti, Stamatina, Ilsley, Mary, Ilves, Lorna, Ilyas, Fatima Mariam, Imam-Gutierrez, La'ali, Iman, Mohamed, Imray, Christopher, Imtiaz, Haider, Ingham, 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Khan, Rahila, Khan, Shabana, Khan, Shahul, Khan, Shoaib, Khan, Tasaduksultan, Khan, Waleed, Khan, Waseem, Khan, Zuhair, Khan Tharin, Mohammad S, Khatana, Usman F, Khatri, Januka, Khatri, Jibran, Khatri, Jyoti, Khatun, Hafiza, Khatun, Taslima, Kheia, Mena, Khera, Jacyntha, Khin, Htet Htet Ei, Khoja, Najaf, Khokhar, Kiran, Khong, Minh Quang, Khoo, Joshua, Khurana, Chloe, Kibaru, Joyce, Kibutu, Faith, Kidd, Andrew, Kidd, Michelle, Kidney, Joe, Kidney, Shane, Kieffer, Will, Kilbane, James, Kilby, Caroline, Killen, Eileen, Kilner, Beverley, Kilroy, Susan, Kim, Bomee, Kim, Jee W, Kim, Minhee, Kimber, Aly, Kimber, Sarah, King, Andy, King, Barbara, King, Hayley, King, Jennifer, King, Jenny, King, Kirsten, King, Matthew, King, Rachel, King, Sarah, King, Victoria, King-Oakley, Emily, Kingsmore, Laura, Kinnear, Deborah J, Kinney, Fiona, Kiran, Sidra, Kirby, Alison, Kirk, Adam, Kirk, Jeremy, Kirk, Jill, Kirk, Jodie, Kirkby, Amy, Kirkham, Emily, Kirkman, Gemma, Kirkpatrick, Lucy, Kirwan, Ursula, 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Shondipon, Lahane, Sushil, Lai, Clement, Lai, James, Laidler, Paula, Laing, Robert, Laing-Faiers, Inez, Laity, Emily, Lake, Katharine, Lakeman, Nicki, Lalloo, David, Lalloo, Fiona, Lam, Alison, Lam, Classy, Lamb, Fiona, Lamb, Lucy, Lamb, Thomas, Lambert, Oscar, Lambert, Pauline, Lameirinhas, Claudia, Lami, Mohammed K G, Lamont, Holly, Lamparski, Michal, Lamrani, Djillali, Lanaghan, Christine, Lancona-Malcolm, Ivone, Landers, Geraldine, Landray, Martin J, Lane, Matthew, Lane, Nicholas, Lang, Alidih, Lang, Stephen, Langer, Daniel, Langley, Margaret, Langoya, Charles, Langridge, Emma, Langthorne, Emily, Langton, Helen, Lara, Beatriz, Large, Taiya, Lartey, Lawrencia Naadu, Lassa, Samuel, Last, Anna, Latham, Scott, Latham, Victoria, Latheef, Afzal, Latif, Larissa, Latt, Nang, Lau, Carmen, Lau, Dawn, Lau, Eva, Laura, Gonzalez G, Laurenson, Myra, Lavington, Eloise, Law, Hou, Law, Jessica, Law, June, Law, Kar Y, Law, Penny, Law, Richard, Lawless, Laura, Lawrence, Chris, Lawrence, Emma, Lawrence, Geoffrey, Lawrence, Holly M, Lawrence, Neil, Lawrie, Ryan, Lawson, Louise, Lawson, Natalie, Lawson, Rod, Lay, Michael, Laybourne, Stephen, Laycock, Christine, Layug, Reina, Lazo, Maria, Le, Thi Thao, Le, Vietland, Lea, Amelia, Lea, William, Leach, Louisa E, Leadbitter, Ian, Leahy, Thomas, Lean, Richard, Leandro, Lorna, Leaning, Darren, Leary, Ruth, Leason, Sandra, Ledingham, Marie A, Lee, Caroline, Lee, Emma, Lee, Hannah, Lee, Irish, Lee, Joshua, Lee, Judith, Lee, Sam, Lee, Shannon, Lee, Shi Han, Lee, Simon, Lee, Sindy, Lee, Stephanie, Lee, Tracey, Lee, Xiang, Lee, Robyn, Lees, Diana, Lees, Jennifer, Legge, Helen, Leggett, Julian, Leigh-Ellis, Katie, Leitch, David, Leitch, Nicky, Lekoudis, Eleni, Lemessy, Petula, Lemoine, Nicholas, Lenagh, Rebecca, Leng, Katy, Lennon, Katrina, Lennon, Liz, Leonard, Beth, Leonard, Kelly, Leong, Wen, Leopold, Nicky, Lepiarczyk, Oskar, Leslie, Isla, Lestari, Eva Noviani, Lester, Eleni, Levell, Emma, Levett, Chris, Levynska, Anastasia, Lewin, Alice, Lewis, Alison, Lewis, Christopher, Lewis, David, Lewis, Dee, Lewis, Heather, Lewis, Joanne, Lewis, Joseph, Lewis, Kathryn, Lewis, Keir, Lewis, Leon, Lewis, Mandy, Lewis, Marissa, Lewis, Nicolas, Lewis, Robert, Lewis-Clarke, Catherine, Lewszuk, Adam, Lewthwaite, Penny, Ley, Samantha, Liao, Angela, Licence, Victoria, Lieberman, David, Liebeschuetz, Susan, Light, Teresa, Lightfoot, Nicky, Lillie, Patrick, Lillis, Ashling, Lim, Ben, Lim, Carys, Lim, Ee T, Lim, Ivy, Lim, Terence, Lim, Wei Shen, Lim, Wilson, Limb, James, Limbu, Dipraj, Limbu, Usha, Linares, Christian, Linden, Dermot, Lindergard, Gabriella, Lindley, Kate, Lindsay, Charlotte, Lindsay, Emily, Lindsay, Max, Lindsay- Clarke, Helen, Ling, Mirella, Lingam, Claire, Linkson, Linette, Linn, Thinzar, Linney, Mike, Lippold, Conrad, Lipscomb, George, Lipscomb, Karen, Lipskis, Laura, Lisboa, Ana, Lister, Evangeline, Little, Jeff, Little, Sam, Littlejohn, Lucy, Liu, Sky, Liu, Xuedi, Llanera, Daniel K, Llewellyn, Rhiannon, Llewelyn, Martin, Lloyd, Adam, Lloyd, Aimee, Lloyd, Arwel, Lloyd, Oliver, Lloyd, Richard, Lo, Su, Loader, David, Loan, Caroline, Lobosco, Livia, Lock, Lydianne, Lock, Sara, Lock, Stephen, Locke, Angela, Locke, Jacqueline, Locke, Thomas, Lockett, Teresa, Lodge, Jeorghino, Lodhia, Krishan, Lofthouse, Martina, Loftus, Heather, Logan, Meg, Logue, Chloe A, Loh, Sook Yin, Lokanathan, Siddharth, Lomme, Kaatje, London, Emily, Long, Gabriella, Long, Natalie, Longbottom, Katherine, Longhurst, Bev, Longshaw, Mark, Longstaffe, Sarah, Lonnen, Jennifer, Lonsdale, Caroline, Looby, Laura, Loosley, Ronda, Lopes, Liliana, Lopez, Paola, Lopez, Paula, Lord, Robert W, Lord, Stephen, Lorimer, Claire, Loro, Francesco, Lorusso, Rachel, Loughlin, Catherine, Lovegrove, Wayne, Loveless, Robert, Lovell, Maxine, Loverdou, Angeliki, Low, Andrew, Low, Jen Mae, Low, Shona, Lowe, Alastair, Lowe, Catherine, Lowe, Emily, Lowe, Faye, Lowe, Leanne, Lowe, Michael, Lowsby, Richard, Lowthorpe, Vicki, Lubimbi, Gamu, Lubina Solomon, Alexandra, Lucas, Georgia, Lucas, Jacob, Lucey, Alice, Lucey, Olivia, Luck, Suzanne, Lui, Lok Hin, Luintel, Akish, Luke, H, Luke, Jane, Lungu, Naomi, Lunia, Apurva, Lunn, Muriel, Luo, Ji, Luscombe, Mark, Luveta, Jocelyn, Luximon, Cindy N, Lwin, Khine, Lwin, Myat, Lye, Alison, Lyell, Barrie, Lyka, Elisavet, Lynas, Audrey, Lynch, Ceri, Lynch, Daniel, Lynch, Daniella, Lynch, Stephen, Maamari, Rea-Grace, Mabb, Hannah, Mabelin, Louies, Mabeza, George, Macaro, Jessica, Macconaill, Kateryna, Macdonald, Chloe, Macduff, Andrew, Macfadyen, Claire, Macfarlane, James G, Macfarlane, Jill, Macfarlane, Laura, Macharia, Irene, MacInnes, Lisa, MacIntyre, Iain, MacIntyre, Jill, Mack, Kirsten, Mackay, Callum, Mackay, Euan, Mackay, Laura, Mackenzie, Alexander, Mackenzie, Matt, MacKenzie Ross, Robert, Mackey, Ami, Mackie, Fiona, Mackie, Jennifer, Mackie, Robert, Mackinlay, Carolyn, Mackintosh, Claire, Mackintosh, Katherine, MacLeod, Mary J, Macleod, Shona, Macmahon, Michael, MacNair, Andrew, Macphee, Catherine, Macpherson, Iain, Macrae, Catriona, MacRaild, Allan, Madani, Yasser, Madden, Alannah, Madden, Mary, Madden-McKee, Christopher, Maddison, Sally, Madeja, Norman, Madhivathanan, Pradeep, Madhusudhana, Madhavi, Madu, Alpha, Madziva, Lorraine, Mafham, Marion, Magee, Nick, Magezi, Frederick, Maghsoodi, Negar, Magier, Christopher, Magnaye, Lessica M, Magriplis, Marios, Magtalas, Michelle, Mahabir, Natasha, Mahadevan-Bava, Subramanian, Maharajh, Amitaa, Maharajh, Anjanie, Maharjan, Kijan, Maharjan, Madan, Mahaveer, Ajit, Mahay, Bal, Mahay, Kanta, Mahdi, Amy, Mahdi, Hibo, Mahdi, Noor, Mahendiran, Thushika, Mahendran, Siva, Maher, Sarah, Maheswaran, Anistta, Maheswaran, Shameera, Maheswaran, Tina, Mahjoob-Afag, Parisa, Mahmood, Ahmed, Mahmood, Farhana, Mahmood, Hussain, Mahmood, Waheed, Mahmood, Zahra, Mahmoud, Hager, Mahmud, Mohammed, Mahony, Ewan, Mahungu, Tabitha, Maiga, Oumou, Mair, Luke, Majekdunmi, Toluwani, Majid, Kesson, Major, Amy, Major, Rupert, Majumdar, Jaydip, Majumder, Mohammad K H, Mak, Tsz L A, Makan, Annabel, Makanju, Esther, Makin, Stephen, Makinde, Wura-Ola, Makkeyah, Yahya, Malanca, Marius, Malcolm, Hannah, Malein, Flora, Malhan, Neeraj, Malicka, Agnieszka, Malik, Ayesha, Malik, Gulshan, Maljk, Mohammed, Mallett, Paul, Mallinder, Petrina, Mallison, Georgia, Mallon, Louise, Malone, Edward, Maloney, Gracie, Mamman, Madhu, Man, Irene, Man, Kathy, Mancinelli, Rossana, Mancuso-Marcello, Marco, Mandal, Shrawan K, Mandal, Sudeshna, Manders, Tracy, Manderson, Lauren, Mandeville, Justin, Mane, Tara, Manhas, Roope, Maniero, Carmen, Manikonda, Ravi, Manjra, Ilham, Mankiewitz, Rowan, Mann, Bobby, Manning, Jonathan, Manning, Sarah, Mannion, Pascoe, Mansi, Katherine, Manso, Katarina, Mansour, Dina, Mansour, Mohamed, Mansour, Ramy, Mapfunde, Isheunesu T, Mappa, Predeesh, Maqsood, Arrusaw, Maraj, Hemant, Marchand, Clare, Marcus, Neil, Marcyniuk, Anna, Marecka, Maria, Maren, Deborah, Margabanthu, Gomathi, Margalef, Jordi, Margarit, Lavinia, Margaritopoulos, Georgios, Margarson, Mike, Maria del Rocio, Fernandez, Maria Pfyl, Teresa, Mariano, Victor, Maric, Ashleigh, Markham, Grace, Marks, Ben, Marks, Maria, Marks, P, Marler, Emily, Marouzet, Elisabeth, Marriott, Arran, Marriott, Cheryl, Marriott, Nemonie, Marsden, Christopher, Marsden, Karen, Marsden, Paul, Marsden, Sarah, Marsden, Tracy, Marsh, Cathryn, Marsh, Glen, Marsh, Robyn, Marshall, Adam, Marshall, Andrew, Marshall, Gail, Marshall, Henry, Marshall, Jaimie, Marshall, Jenna, Marshall, Nicola, Marshall, Riley, Marshall, Steven, Marshall, Jennifer, Martin, Emmeline, Martin, Gaynor, Martin, Hayley, Martin, Hope, Martin, Jane, Martin, Karen, Martin, Kate, Martin, Laila, Martin, Martha, Martin, Michael, Martin, Noelia, Martin, Tim, Martin, Winston, Martin, Sarah, Martindale, Tim, Martineau, Marcus, Martinez, Lauren, Martinez Garrido, Jose C, Martin-Lazaro, Juan, Maruthamuthu, Vijay K, Marwan, Bukhari, Maryan, Gemma, Mary-Genetu, Roman, Maryosh, Sam, Masani, Vidan, Mascagni, Allison, Maseda, Diego, Maseko, Zandile, Mashate, Sheila, Mashhoudi, Yasaman, Mashta, Al, Masih, Izhaq, Masih, Sanna, Maskell, Nicholas, Maskell, Perry, Maskey, Prabina, Masoli, Matthew, Mason, Julia, Mason, Rebecca, Mason, Richard, Mason, Ruth, Mason, Claire, Masood, Mohammad, Masood, Mohammad T, Masood, Syed S M E, Massa, Thalia, Massey, Ian, Masters, Joseph, Masud, Aaqib, Matapure, Lear, Matei, Cristina, Matewe, Ropafadzo, Matey, Esther, Matharu, Manraj, Mathen, Stephy, Mather, Alex, Mather, Nicole, Mathers, Jonathan, Matheson, Joanna, Mathew, Amal, Mathew, Anna, Mathew, Bijoy, Mathew, Moncy, Mathew, Verghese, Mathews, Jesha, Mathias, Kate, Mathioudakis, Alexander, Matila, Darwin, Matimba-Mupaya, Wadzanai, Matin, Nashaba, Matisa, Elina, Matkins, Ellen, Matonhodze, Max, Matovu, Elijah, Mattappillil, Jaysankar, Matthews, Alison J, Matthews, Clive, Matthews, Heather, Matthews, Helen, Mattocks, Lehentha, Maughan, Charlotte, Maulidya, Tara Titian, Mawson, Emma, Maxton, Fiona, Maxwell, Adam, Maxwell, Veronica, May, Emily, May, James, May, Joanne, May, Philippa, Mayanagao, Irving, Maycock, Matthew, Mayer, Jordan, Mayers, Graham, Maynard, Victoria A, Mayo, Thomas, Mayola, Lioniza, Mayor, Shelley, Mazen, Ibreaheim, Mazhani, Thamani, Mazzella, Andrea, Mburu, Nyambura, Mbuyisha, Angeline, Mc Cague, Celine, McAleese, Eleanor, McAlinden, Paul, McAllister, Lesley, McAlpine, Audrey, McAlpine, Graeme, McAndrew, Jonathan, McAuley, Hamish, McAuliffe, Sarah, McBrearty, Claire, McBride, Erin, McBuigan, Michael, McBurney, James, McCabe, Laura, McCafferty, Gemma L, McCafferty, Laura, McCairn, Amanda, McCammon, Jake, McCammon, Nicole, McCann, Conor, McCann, Erin, McCarrick, Alexandra, McCarron, Brendan, McCarthy, Eoghan, McCarthy, Michelle, McCarthy, Natalie, McCaughey, Sinead, McClay, Tara, McClelland, Beverley, McClintock, Declan, McCloskey, Michael, McCollum, Kirsten, McCorkindale, Alasdair, McCormack, Patricia, McCormick, Jacqueline, McCormick, Jake, McCormick, Wendy, McCourt, Paul, McCrae, Jame, McCready, Sharon, McCreath, Gordan, McCreedy, Helen, McCue, Claire, McCullagh, Iain J, McCullagh, Liz, McCullagh, Megan, McCullough, Conor, McCullough, Katherine, McCullough, Nicola, McCullough, Sarah, McCurrach, Fiona, McDermott, John, McDermott, Paula, McDermott, Rory, McDevitt, Katharine, McDill, Helen, McDonald, Basil, McDonald, Carly, McDonald, Claire, McDonald, Debbie, McDonald, Rob, McDonald, Sam, McDonald, Damhnaic, McDonnell, Natasha, McDougall, Catherine, McDougall, Lilly, McDougall, Rowan, McEleavy, Irene, McElwaine, Fred, McEntee, Julie, McEvoy, Evanna, McEwan, Claire, McEwen, Ruth, McFadden, Margaret, McFarland, Denise, McFarland, Margaret, McFarland, Rachel, McFlynn, Joe, McGarry, Erin, McGarvey, Lorcan, McGeachan, Alex, McGee, Frederick, McGenily, Laura, McGettigan, Clodagh, McGettrick, Michael, McGhee, Christopher, McGill, Fiona, McGinnity, Sarah, McGlinchey, Neil, McGlone, Phil, McGlynn, Deborah, McGoldrick, Claire, McGoldrick, Clare, McGough, Elizabeth, McGovern, Christopher, McGovern, Roisin, McGowan, Angela, McGown, Anne, McGrath, Brendan, McGregor, Amanda, McGregor, Annemarie, McGuigan, Michael P, McGuinness, Heather, McGuire, Sean, McHugh, Tara, McInnes, Caroline, McInnes, Neil, McIntosh, Jerome, McIntyre, Karen, McIntyre, Mhairi, McKay, Lorna, McKeag, Conor P, McKeane, Jacqueline, McKee, Madeleine, McKeever, Joseph, McKenna, Judith, McKenna, Shirley, McKenzie, Mary, McKeogh, Donogh, McKerr, Caroline, McKie, Anthony M, Mckie, Hayley, Mckie, Laura, McKnight, Gerard, McLachlan, Heather, McLaren, Andrew, McLaren, Barbara, McLarty, Nicola, Mclaughlan, Danielle, McLaughlin, Maria, McLay, James, McLeish, Mary, McLennan, Tina, McLure, Stewart, McMahon, Anne Marie, McMahon, Genevieve, McMahon, Mike, McMahon, Stephen, McManus, Terence, McMaster, Moyra, McMaster, P, McMaster, Paddy, Mcmeeken, Faye, McMeekin, Samuel, McMillan, Nicola, McMillen, Katherine, McMinn, Jason, McMorrow, Liam, McMullen, Heather, McMurran, Christopher, McNally, Helen, McNeela, Fiona, McNeil, Lynne, McNeill, Claire, McNeill, Jessica, McNeill, Shea, McNelis, Una, McNulty, Melanie, McNulty, Roisin, McParland, Christopher, McPhail, Mark, McQueen, Alison, McSkeane, Anna, McSorland, Denise, McSorley, Therese, McTaggart, Gini, McTaggart, Jacqueline, Mead, Joanna, Mead, Paul, Meadows, Emma, Meakin, Olivia, Mearns, Ben, Mearns, Claire, Mears, Kim, Mears, William, Meda, Manjula, Mediana, Ayren, Medine, Ross, Medveczky, Thomas, Meehan, Sharon, Meeks, Emily, Megan, Abbi, Meghani, Nevan, Meghjee, Salim, Megson, Sharon, Mehar, Amina, Mehmood, Mehr N, Mehra, Rohan, Mehta, Rohan, Meintjes, Graeme, Meirill, James, Meiring, James, Mejri, Rayane, Mekonnen, Ellen, Melander, Sabina, Melinte, Adriana-Stefania, Mellersh, Jennifer, Melling, Lucy, Mellish, Christie, Mellor, Francesca, Mellor, Joe S, Mellor, Samantha, Mellor, Zoe, Mellows, Katrina, Melnic, Vladimir, Melville, Alice, Melville, Dominique, Melville, Julie, Membrey, Helen, Mencias, Mark, Mendelski, Adam, Mendelson, Marc, Mendonca, Cheryl, Meney, Carron, Menezes, Colin, Mensah, Winifred, Mentzer, Alexander, Menzies, Dan, Menzies, Sarah, Mepham, Sue, Mercer, Oliver, Mercer, Pauline, Merchant, Arwa, Merchant, Fatema, Mercioniu, Mihaela, Meredith, Megan, Merida Morillas, Marta, Merrick, Blair, Merritt, Jack, Merritt, Sharon, Merritt, Simon, Merron, Paul-Peter, Merwaha, Ekta, Message, Simon, Messenger, Jenny, Metcalf-Cuenca, Gabriel, Metcalfe, Alexandra, Metcalfe, Benjamin, Metcalfe, Kneale, Metherell, Stella, Metryka, Alexsandra, Mew, Louise, Meyrick, Simon, Mguni, Nhlanhla, Miah, Atiqa, Miah, Jagrul, Miah, Nahima, Mian, Areeb, Mic, Gabriela, Micah-Amuah, Lawrence, Micallef, Dariush, Michael, Alice, Michael, Angiy, Michael, Shery, Michalak, Natalia, Michalca-Mason, Loredana, Michalec, Ola, Middle, Janet, Middleton, Hayley, Middleton, Jennifer T, Middleton, Maeve, Middleton, Sophie, Mieres, Shelley, Mihalca-Mason, Loredana, Mikolasch, Theresia, Milgate, Sarah, Millar, Colin, Millar, Jonathan, Millard, James, Miller, David, Miller, Johnathan, Miller, Lucy, Miller, Rachel, Miller-Biot, Naomi, Miller-Fik, Alex, Millett, Louise, Milligan, Barry, Milligan, Hazel, Milligan, Iain, Milliken, Caitlin, Millington, Katherine, Millington, Rhys, Millington, Samuel, Mills, Helen, Mills, Janet, Mills, Rebecca E, Millward, Helen, Miln, Rebecca, Milne, Alice, Milne, Charlotte, Milne, Louise, Milner, Joanne, Milner, Leanne, Min, Zayar, Mindel, Samuel, Minkah, Prince Amankwah Baffour, Minnis, Chrissie, Minnis, Paul, Minou, Konstantina, Minskip, Natalie, Minton, Jane, Miranda, Frederico, Mirela, Mukaj, Mirza, Taimur, Misbahuddin, Anjum, Mishra, Aseem, Mishra, Biswa, Mishra, Eleanor, Mishra, Ritu, Misra, Sannidhya, Mistry, Deena, Mistry, Heena, Mital, Dushyant, Mitchard, Sarah, Mitchell, Ben, Mitchell, Caroline, Mitchell, Luke J, Mitchell, Piers, Mitchelmore, Philip, Mitra, Andrew, Mitra, Atideb, Mitra, Sandip, Mlambo, Nomsa, Moakes, Emma, Moar, Kirsten, Moatt, Emma, Mock Font, Daniela, Modgil, Gita, Mohamed, Abdelrahman, Mohamed, Arez, Mohamed, Osab, Mohammad, Akram, Mohammad, Waheed, Mohammed, Aliabdulla, Mohammed, Omer, Mohammed, Yaser N S, Mohamud, Bilal A, Moharram, Amr, Mok, Hoi-Ping, Mok, Jonathan, Mokogwu, Leslie, Molina, Marcelino, Moller-Christensen, Christine, Mollet, Mateus, Molloholli, Malid, Molloy, Aoife, Molloy, Linda, Molyneux, Andrew, Molyneux, Rebekah, Momoniat, Tasnim, Monaghan, Holly, Monaghan, Krista, Mongolu, Shiva, Monika, Tesha, Monsell, Katelyn, Montasser, Mahmoud, Montgomery, Alan, Montgomery, Hugh, Moodley, Prebashan, Moody, Margaret, Moody, Nick, Moon, Angela, Moon, James, Moon, Ji-Hye, Moon, Maria, Moonan, May, Moondi, Parvez, Moorby, Suzanne, Moorcroft, Jim, Moore, Alex, Moore, Christopher, Moore, David A J, Moore, Faye, Moore, Judith, Moore, Laura, Moore, Natalie, Moore, Sally, Moore, Siobhan, Moore, Sonia, Moore, Vanessa, Moores, Rachel, Morab, Ed, Morales, Jose, Moramorell, Nuria, Moran, Louise, Moray, Grishma, Moreno-Cuesta, Jeronimo, Morgan, Alexander, Morgan, Amy, Morgan, Caitlin, Morgan, Christine, Morgan, Colin, Morgan, Holly, Morgan, Katie, Morgan, Lauren, Morgan, Leila, Morgan, Lewis, Morgan, Matthew, Morgan, Patrick, Morgan-Jones, Katie, Morgan-Smith, Emily, Morilla, Joseph, Morley, Anna, Morley, Thomas, Morley, Wendy, Morris, Anna, Morris, Damian, Morris, Fiona, Morris, Helen, Morris, Juliet, Morris, Katie, Morris, Laura, Morris, Lucy, Morris, Mary-Anne, Morris, Niall, Morris, Paul, Morris, Sheila, Morris, Susan, Morrison, Douglas, Morrison, Moira, Morrison, Scott, Morrissey, Mary, Morrow, Abbie C, Morrow, Anna, Morselli, Franca, Mortem, Gordon, Mortland, Valerie, Morton, Chelsea, Morton, Gordon, Morzaria, Priti, Mosby, Daniel, Moseley, Linda, Moshal, Karyn, Moshy, Ben, Moss, Alison, Moss, Charlotte, Moss, James, Moss, Sarah, Moss, Stuart, Mostafa, Omar, Moth, Georgia, Motherwell, Nicki, Mottershaw, Sharon, Moudgil, Harmesh, Mouland, Johanna, Moulds, Caroline, Moulton, Hilary, Mounce, Ginny, Mousley, Elizabeth, Mowatt, Chris, Moxham, Karen, Moya, Borja, Moyo, Quberkani, Mshengu, Eunice, Mtuwa, Sheila, Muazzam, Ali, Muazzam, Iqtedar A, Muchenje, Nykki, Mudawi, Dalia, Muddegowda, Girish, Mufti, Rabia, Mugal, Imran, Mughal, Ahsan, Muglu, Javaid, Muhammad, Fawad, Muhammad, Javed, Muir, Carol, Mukherjee, Aparna, Mukherjee, Dipak, Mukhtar, Jameel, Mukhtar, Syed A A, Mukimbiri, Denise, Mulcahy, John, Mulcahy, Michelle, Mulgrew, Peter, Mulhearn, Ben, Mulla, Arafat, Mullan, Dee, Mullasseril Kutten, Dileepkumar, Mullen, Niall, Mullett, Rosemary, Mulligan, Ciara, Mulligan, Sandra, Mumelj, Lana, Mumford, Andrew, Munavvar, Mohammed, Munby, Henry, Munday, Hannah, Munro, Anne-Marie, Munt, Sheila, Mupudzi, McDonald, Murad, Arshid, Muraina, Oluwatosin H, Muralidhara, Koteshwara, Murdoch, Mhairi, Murira, Jennifer, Murphy, Alison, Murphy, Ben, Murphy, Carl, Murphy, Cathal, Murphy, Erin, Murphy, Gail, Murphy, Hannah, Murphy, Peter, Murphy, Rebecca, Murphy, Sheenagh, Murphy, Simon, Murray, Clare, Murray, David, Murray, Dawn, Murray, Eleanor, Murray, Katie, Murray, Kenneth, Murray, Lindy, Murray, Lisa, Murray, Lorna, Murray, Tracey, Murtagh, Eoin, Murthy, Mithun, Murton, Catherine, Murton, Rosie, Muru, Neeka, Musanhu, Rosemary, Mushabe, Maimuna, Mushtaq, Omaisa, Musini, Sohmal, Mustafa, Ahmed M M, Mustafa, Elhaytham, Mustafa, Mustafa, Mustapha, Ibrahim, Mustfa, Naveed, Mustufvi, Zhain, Mutch, Callum, Mutch, Rachel, Mutema, Eric, Muthukrishnan, Balakumar, Mutton, Sheree, Muzengi, Natasha, Mwadeyi, Memory, Mwale, Bettina, Mwaura, Esther, Myagerimath, Raji, Myers, Alice, Myers, Sam, Myerson, James S, Myint, Khin Swe, Myint, Yadee, Mynott, Georgina, Myslivecek, Libor, Nabayego, Patricia, Nadar, Evelyn, Nadeem, Iftikhar, Nadheem, Moosa, Nadjm, Behzad, Naeem, Asma, Naeem, Hassan, Naeem, Salman, Nafees, Samraiz, Nafei, Mohamed, Naftalia, Widya, Nagarajan, Thapas, Naglik, Leah, Nagra, Imrun, Nagra, Deepak, Naguib, Mina, Naguleswaran, Kirushthiga, Nagumantry, K Shonit, Naicker, Kevin, Naidoo, Sarveshni, Naik, Gireesha, Naik, Rishi, Naik, Samir, Nair, Devu S, Nair, Rajiv, Nair, Tanushree, Naisbitt, Jay, Naismith, Kerry, Nakiboneka-Ssenabulya, Deborah, Nallapareddy, Sri, Nallapeta, Soum, Nallasivan, Arumugan, Nam, Ha Xuan, Nanda, Uttam, Nandani, Aarti, Nandwani, Tara, Naqvi, Ali Raza, Naqvi, Asadullah, Naqvi, Sara, Nasa, Sophia, Nash, Dominic, Nasheed, Nader, Nasimudeen, Abdul, Nasir, Umer, Nasronudin, Nasronudin, Nasser, Tahir, Natarajan, Anuja, Natarajan, Geetha, Natarajan, Nalin, Natarajan, Nikhila, Natarajan, Rajkumar, Nath, Preethy, Nathaniel, Noel, Nathvani, Mala, Nathwani, Priyan, Nava, George, Navaneetham, Neena, Navaratnam, Jeya, Navarra, Helen, Naveed, Sadaf, Navin, John, Nawaz, Khuteja, Nawaz, Sarfaraz, Nawaz, Shasta, Nayar, Bonilla, Naylor, Suzanne, Nayyar, Moez, Naz, Farrah, Naz, Mobeena, Nazari, Babak, Nazir, Abida, Nazir, S, Nazir, Sehar, Ncomanzi, Dumisani, Ndefo, Onyinye, Ndoumbe, Narcisse B, Neal, Abigail, Neal, Alan, Neary, Elaine, Negmeldin, Mostafa, Neil, Jonathan, Neill, Paula, Neils, Hector E, Nejad, Avideah, Nel, Jeremy, Nel, Louise, Nelson, Andrew, Nelson, Benjamin, Nelson, Lauren, Nelson, Marie, Nelson, Memory, Nelson, Richard, Nelson, Scott, Nelson, Sven, Nelwan, Erni, Nemane, Rajesh, Nepal, Samiksha, Nethercott, Daniel, Netherton, Kimberley, Nettleton, Kimberley, Neupane, Kabita, Newby, Alison, Newby, Angela, Newby, David, Newcombe, Tracy, Newell, Helen, Newman, Charlotte, Newman, Diana, Newman, Hannah, Newman, Julie, Newman, Oscar, Newman, Tabitha, Newman, Thomas, Newport, Rachel, Newton, Maria, Ng, Anthony Y K C, Ng, Hui En Jewel, Ng, Ka Wing, Ng, Maxine, Ng, Sarah, Ng, Wee Jin, Ng, Yee W M, Ngan, Thomas, Ngo, Thanh Ha, Ngui, Gabriel CE, Ngumo, Alice, Nguyen, Hong Khanh, Nguyen, Minh Thu, Nguyen, Nguyen Thi Thao, Nguyen, Quang, Nguyen, Thi Huyen Trang, Nguyen, Thi Thao, Nguyen, Thi Thao Nguyen, Nguyen, Thi Thuong, Nguyen, Thi Thuy Phuong, Ngwenya, Keith, Nic Fhogartaigh, Caoimhe, Nicholas, Nathalie, Nicholas, Philip, Nicholas, Rachel, Nicholas, Rebecca, Nicholls, Donna, Nicholls, Lisa, Nicholls, Sarah, Nicholson, Alice, Nicholson, Anne, Nicholson, Annette, Nickson, Ian, Nicol, Eileen, Nicol, Elizabeth, Nicol, Rebecca, Nicola, Pantelis, Nicoll, Antony, Nightingale, Tania, Nikita, Faria, Nikolaos, Pantzaris, Nikonovich, Georgii, Nilsson, Annette, Nimako, Kofi, Nimako, Louise, Nimmo, Camus, Ninan, Preethy, Nirmalan, Mahesh, Niroula, Richa, Nisar, Attiya, Nisar, Muhammad, Nisar, Tosia, Nisbett, Toby, Nisha James, Aksinya, Nishat, Sabaahat, Nishiyama, Tomoko, Nix, Sara, Nixon, Jennifer, Nixon, Maxine, Nizam Ud Din, Khwaja, Nizami, Maria, Nizamis, Serafeim, Njafuh, Raymond, Noakes, India, Noba, Lyrics, Noble, Jennifer, Noble, Jonathon, Noble, Harriet, Noe, Hsu M, Nolan, Jerry, Nolasco, Jackson, Noor, Zahid, Noori, Zaid, Norcliffe, Jayne, Norman, Louis, Norman, Rachel, Norris, Emma, Norris, Karen, Norris, Lillian, Nortcliffe, Sally Ann, North, Fiona, North, Julie, North, Thomas, Northfield, John, Northover, Samantha, Nortje, Jurgens, Norton, Donna, Norton, Rowen, Notman, Holly, Nourein, Khalid, Novak, Timea, Novas Duarte, Nuria, Novis, Catherine, Nowak, Justyna A, Nu, Khin Phwe, Nugdallah, Mohamed, Nugent, Anne M, Nugent, Justine, Nugroho, Cahyo Wibisono, Numbere, Numbere, Nundlall, Kribashnie, Nune, Arvind, Nunn, Kieran, Nunn, Michelle, Nunnick, Jane, Nupa, Yvonne, Nur, Fadumo, Nurgat, Zubeir, Nuttall, Amy, Nwafor, Lorenza, Nwajiugo, Paul C, Nyamugunduru, Godfrey, Nyanor, Livina, Nyirenda, Maggie, Nyland, Kerry, O Rinn, Donal, O Shea, Daire, O Toole, Megan, O'Hara, Marianne, O'Hara, Chloe, O'Keefe, Laura, O'Reilly, Kevin, O'Rourke, William, Oakley, Caroline, Oakley, Naomi, Oakley, Susan, Obale, Begho, Oboh, Clements, O'Brien, Clare, O'Brien, Julie, O'Brien, Kirsty, O'Brien, Linda, O'Brien, Neale, O'Brien, Rachel, O'Brien, Tracey, O'Bryan, Emma, Obukofe, Ross, O'Callaghan, Christopher, O'Connell, Lorcan, OConnor, Tadg, O'Connor, Chris, O'Connor, Grainne, Odam, Miranda, Oddie, Sam, Oddy, Sharon, Odedina, Yejide, Odedra, Krishma, Odelberg, Sven W, Odell, Natasha, Oderinde, Omolola, Odone, Jessica, O'Donohoe, Lynn, O'Donovan, Catherine, Odysseos-Beaumont, Isabel, O'Farrell, Stephen, Offord, Pamela, O'Flaherty, Morgan, Ofori, Emmanuel, Ogbara, Tanwa, Ogilvie, Catherine, O'Gorman, Ciaran, Ogunjembola, Ibrahim, Ogunkeye, Oluwatomilola, Ohia, Udeme, Ojha, Shalini, Ojha, Sushma, Ojo, Ohiowele, O'kane, Fiona, O'Kane, Mark, Okeke, Tolu, OKell, Eleanor, Okines, Alicia, Okpala, Iheoma, Okpo, Ernest, Okpoko, F, Okubanjo, Maryanne, Oladipo, Chiamaka, Olaivar, Liel A, Olaiya, Raphael, Olatujoye, Jacob, Old, Tim, Oleszkiewicz, Gregory, Oliver, Annie, Oliver, Catherine, Oliver, Jesse, Oliver, Lucinda, Oliver, Martyn, Oliver, Zoe, Olokoto, Nurudeen O, Olonipile, Folusho, Olufuwa, Olumide, Olukoya, Olatomiwa, Oluwole-Ojo, Akinlolu, O'Malley, Laura, Omane-Donkor, Priscilla Kesewaa, Omar, Maryam, Omar, Mohamad, Omar, Zohra, Omer, Nimca, Omoregie, Eti, O'Neill, Connaire, O'Neill, Lauran, Ong, Chon Sum, Onuoha, Onyinye, Onyeagor, Chidera, Oo, Chan Nyein, Oo, Zin Nwe, Ooi, Huah Chiang, Ooi, Sze Hwei, Oomatia, Amin, Opata, Alfred, Opena, Maria, Oram, Richard, Ord, Christy, Ord, Jonathan, Oreilly, Clare, Orekoya, Lola, O'Riordan, Devaki, O'Riordan, Sean, Orlikowska, Izabela, Orme, Amy, Orme, Hannah, O'Rourke, Laura, Orr, Charlotte, Orr, Sarah, Orton, Christopher, Osadcow, Anna, Osagie, Rawlings, Osanlou, Rostam, Osborne, Lynn, Osborne, Nigel, Osborne, Rebecca, Osborne, Wendy, Osborne, William, Osbourne, Charles, Osei-Bobie, Jennifer, Osman, Joseph, Osman, Wa'el, Osman, Bashir, Osoata, G, Ostermann, Marlies, O'Sullivan, Eoin, O'Sullivan, Susan, Oteng, Mercy Adomah, Otey, Noor, Otite, Otheroro K., O'Toole, Marie, Ouyang, Jingxiu, Owen, Rachel, Owen, Stephanie, Owens, Emma, Owoseni, Yetunde, Owston, Michael, Oxlade, Ruth, Ozdes, Feray, Pack, Jamie, Packham, Alice, Packham, Sophie, Paczko, Piotr, Padden, Grace, Padmakumar, Anand, Page, Catrin, Page, Iain, Page, Joseph, Page, Shannon, Page, Valerie, Paget, Jodi, Pagett, Katherine, Paisley, Lee, Pajak, Susannah, Pajak, Susie, Pakou, Glykeria, Pakozdi, Angela, Pal, Soubhik, Pal, Sushi, Palacios, April, Palagiri Sai, Vishnu B, Palaniappan, Vadivu, Palanivelu, Priya, Palfreeman, Adrian, Palfrey, Heather, Palissery, Vinod, Palit, Deepshikha, Pallipparambil Antony, Sherly, Palman, Jason, Palmer, Alistair, Palmer, Helen, Palmer, Janet, Palmer, Lynne, Palmer, Ross, Pambouka, Andrea, Pamphlett, Ian, Pan, Daniel, Pandey, Anmol, Pandian, Nithya, Pandya, Krishnaa, Pandya, Tej, Paneru, Hem Raj, Panes, Alice, Pang, Jessica, Pang, Yee Wei, Pangeni, Raju, Pannell, Laura, Pannu, Kanwar, Pant, Suman, Panthakalam, Sathianathan, Pantin, Charles T, Pao, Norman, Papaconstantinou, Helen, Papavarnavas, Nectarios Sophocles, Papineni, Padmasayee, Paques, Kitty, Paracha, Abdul W, Paradowski, Kerry, Parambil, Vinay, Paranamana, Supathum, Parashar, Siddhant Raja, Parberry, Ian, Parekh, Amy, Parekh, Dhruv, Parfitt, Louise, Parfrey, Helen, Parikh, Omi, Parish, Gemma, Park, John, Parkash, Vivak, Parker, Angela, Parker, Ben, Parker, Emma, Parker, Helen, Parker, Jacob, Parker, Julie, Parker, Laura, Parker, Lucy, Parker, Natasha, Parker, Nicola, Parker, Sara, Parker, Sean, Parkin, Kirstin, Parkinson, Anna, Parkinson, Molly, Parkinson, Valerie, Parmar, Chetan, Parmar, Viraj, Parris, Victoria, Parrish, Chloe, Parry, Bethan, Parry, Helen C, Parslow-Williams, Siobhan, Parsonage, Maria, Parsons, Georgie, Parsons, Joseph, Parsons, Penny, Partridge, Richard, Parvez, Zeeshan, Parvin, Kevin, Passby, Lauren, Passey, Samuel, Passmore, Heather, Pastrana, Juan, Patachako, Jonathan, Patal, Mital, Patch, Sarah, Patel, Aamie, Patel, Alkesh, Patel, Amisha, Patel, Bijal, Patel, Dakshesh, Patel, Darshna, Patel, Hemani, Patel, Jaymik, Patel, Kamal, Patel, Kayur, Patel, Kiran, Patel, Krish, Patel, Manish, Patel, Margi, Patel, Martyn, Patel, Mehul, Patel, Naleem, Patel, Nehalbhai, Patel, Prital, Patel, Saagar, Patel, Sanjay, Patel, Soonie, Patel, Trishna, Patel, Zaakirah, Patel, Vishal, Paterson, Kirsteen, Pathak, Sangeeta, Pathak, Sunil, Pathan, Nazima, Patience, Alexandra, Patience, Donna, Patmore, Russell, Patole, Sonia, Paton, Lia, Patrick, Abigail, Patrick, Georgie, Patrick, Jean, Patten, Simon, Pattenden, Ben, Patterson, Charlotte, Patterson, Jean, Patterson, Linda, Patterson, Molly, Patterson, Robert, Pattrick, Martin, Paudel, Damodar, Paudel, Kamala, Paudel, Manu, Paudel, Suman, Paul, Moriarty, Paul, Suman, Pauls, Leigh, Paulus, Stephane, Pavely, Amelia, Pavitt, Matthew J, Pavord, Susan, Payne, Brendan, Payne, Elizabeth, Payne, Mark, Payne, Ruth, Peacock, Linda, Peacock, Louise, Peacock, Sarah, Peake, Henry, Pearce, Jasmine, Pearse, Rachel, Pearse, Rupert, Pearson, Andrew, Pearson, Daniel, Pearson, Harriet, Pearson, Karen, Pearson, Samuel A, Pearson, Sandra, Peasley, Alice, Peddie, Hilary, Peebles, Steven, Peek, Russell, Peer, Adam, Peerbhoy, Shahid, Pegg, Claire, Peggie, Eleanor, Peggie, Hannah, Peglar, Suzannah, Peirce, Benjamin H, Peirse, Mary, Pelham, Claire, Pemberton, Abigail, Penacerrada, Melchizedek, Pender, Anthony, Pendlebury, Carmel, Pendlebury, Jessica, Penfold, Rachel, Penman, Catherine, Penman, Julie, Penman, Rachel, Penner, Justin, Penney, Kristi, Pennington, Anna, Penny, James, Pepperell, Justin, Percival, Rachel, Pereira, Adriana, Pereira, Rita, Pereira Dias Alves, Carlota, Perera, Indika, Perera, Marek, Perez, Elena, Perez, Jane, Perinpanathan, Tanaraj, Periyasamy, Lakshmi, Perkins, Emma, Pernicova, Ida, Perritt, Elizabeth, Perry, Alice, Perry, Alison, Perry, Emily, Perry, Meghan, Perumpral, Thomas M, Pessoa-Amorim, Guilherme, Petch, Ruth, Peter, Lionel, Peters, Cecilia, Peters, Lucy, Peters, Mark, Peters, Steve, Peters, Tim, Petersen, Remy, Peterson, Alexandra, Peto, Leon, Petras, Iulia, Petrova, Boyanka, Petrova, Mirela, Petrovics, Ellen, Pettigrew, Tom, Pezard-Snell, Marius, Pfeffer, Paul, Phalod, Gunjan, Pham, Ngoc Thach, Pham, Van Phuc, Phan, Thi Thu Hien, Phanish, Mysore, Phelan, Paul, Philbey, Christopher, Philbin, Jennifer, Phillips, Aled, Phillips, Alex, Phillips, Bethan, Phillips, Dylan, Phillips, Nicola, Phillips, Patrick, Phillips, Rachael, Phillips, Thomas, Phipps, Marie, Phipps, Michael, Phong, Nguyen Thanh, Phongsathorn, Virach, Phull, Mandeep, Phung, Ho Thi Kim, Phuyal, Anita, Phyo, Aye Kyaw, PI, Myat T T, Pick, Sara, Pickard, James, Pickering, Charlotte, Pickering, Frances, Pickering, Gillian, Pickett, Thomas, Pickles, Joanna, Pickstock, Shirley, Pickwell-Smith, Benjamin, Pieniazek, Natalia, Piercy, Charlie, Pieris, Angelo, Pilgrim, Samia, Pillai, Paul Anthony, Pilling, Laura, Pilsworth, Zoe, Pinches, Heather, Pinches, Stacey, Pine, Kirsty, Pinjala, Muni T, Pintus, Stefania, Piper, Graeme, Pirani, Tasneem, Pitchford, Marie, Pittman, Marcus, Pitts, Sally, Plaatjies, Nicolene, Platt, Naomi, Pleass, Robert, Plowright, Megan, Plummer, Laura, Plumptre, Charles, Pobjoy, Jonathan, Pogreban, Tatiana, Poku, Charles, Poku, Stephen, Polgarova, Petra, Pollard, Rachel, Pollock, Louisa, Poluyi, Oluwamayowa, Polwarth, Gary J, Pomery, Fiona, Ponce, Ida M F, Ponnusamy, Ponmurugan, Ponnusamy, Suresh, Ponnuswamy, Aravind, Ponte Bettencourt dos Reis, Inês, Pooboni, Suman, Poole, Alice, Poole, Lynda, Poole, Michele, Poon, Sharon, Poonian, Tajinder, Porteous, Jack, Porteous, Mark, Porter, David, Porter, Jo, Porter, Linda, Porter, Ross, Posada, Anna, Postlethwaite, Kelly, Potdar, Manoj, Pothecary, Carla, Pothina, Narayana, Potla, Priyadarshan, Potoczna, Dorota, Pott, Jason, Potter, Alison, Potter, Andrew, Potter, Jean, Potter, Sarah, Potter, Tracey, Potton, Elspeth, Potts, Joanne B, Potts, Julie, Potts, Kathryn, Poudyal, Beli, Poultney, Una, Poulton, Katherine, Poustie, Vanessa, Powell, James, Powell, Jordan, Powell, Natassia, Powell, Sandra, Power, Deborah, Power, Nick, Power, Sharon, Poxon, Joseph, Poyner, Emma, Poyner, Robin, Prabhu, Aishwarya, Prabowo, Sandhi, Pradhan, Vidushi, Pradip, Gyanwali, Prady, Helena, Prananingtias, Rosita, Prasad, Aalekh, Prasad, Krishna, Prasad, Usha, Prasanth Raj, Fredy, Prasath, Sangeetha, Pratiwi, Nicky G, Pratley, Anezka, Pratt, Steven, Prayuda, Chrisan Bimo, Preiss, David, Prendergast, Claire, Prentice, Lynn, Prentice, Peter, Prescott, Verity, Presland, Laura, Prest, Catharine, Preston, Stephen, Pretorius, Martha, Prevatt, Natalie, Prew, Sandra, Price, Ashley, Price, Carly, Price, Claire, Price, David, Price, Elizabeth, Price, Katie, Price, Laura J, Price, Nathan, Price, Vivien, Price-Eland, Rachael, Priest, Anne, Prieto, Jimena, Primrose, Lorraine, Prince, Clare, Prince, John, Prince, Judith, Prince, Laura, Pringle, Shirley, Prior-Ong, Melissa, Pristopan, Veronika, Pritchard, Kelly, Pritchard, Lucy, Pritchard, Simon, Priyash, Verma, Procter, Andrew, Proctor, Clare, Protopapas, Mike, Proudfoot, Rebecca, Prudon, Benjamin, Pryor, David, Pudi, Solomon, Puffett, Angela, Pugh, Joanne, Pugh, Lawrence, Pugh, Mark T, Pugh, Nichola, Pugh, Richard, Puisa, Veronika, Puji Lestari, Eni, Puliyakkadi, Safa, Pullen, Jennifer, Punia, Kirandip, Punnilath Abdulsamad, Saleel, Purandare, Laura, Purchase, Daniel, Purdue, Corrina, Purdy, Rachel, Purewal, Bally, Purnell, Rebecca, Pursell, Molly, Purssord, Gregory, Purves, Rory, Purvis, Sarah, Puspatriani, Khairunnisa, Putensen, Daniel, Puvaneswaran, Bhamini, Puxty, Alex, Puxty, Kathryn, Puyrigaud, Zoe, Pyart, Eleanor, Pye, Emily, Pynn, Michael, Qadeer, Tariq, Qayum, Mohammad, Quah, Corrine, Quaid, Sheena, Quail, Nathaniel, Quamina, Charlotte, Quang, Nguyen Ngo, Quartermaine, Georgia, Quasim, Tara, Quayle, Alice, Quek, Eleanor, Quenby, Siobhan, Qui, Xinyi, Quick, Vanessa, Quigley, Julie, Quijano-Campos, Juan-Carlos, Quindoyos, Jhanielle, Quinn, Andrew, Quinn, James, Quinn, Tom, Quratulain, Quratulain, Qureshi, Danya, Qureshi, Ehsaan, Qureshi, Hasanain, Qureshi, Iram, Qureshi, Khadija, Qureshi, Nawaz, Qurratulain, Qurratulain, Qutab, Saad, Rabbani, Muhammad S, Rabinowicz, Simon, Raceala, Madalina, Rachid, Alan, Rachman, Brian Eka, Rachman, Raissa, Rad, Laura, Radford, Jane, Radford, Liz, Radhakrishnan, Jayachandran, Rafferty, Hannah, Rafiq, Muhammad Y, Rafiq, Shabana, Rafique, Cecillia, Rafique, Jethin, Rafique, Muhammad, Ragatha, Ravi, Raghunathan, Aiswarya, Raguro, Abigail, Raha, Shankho D, Rahama, Sana, Rahardjani, Mutia, Rahilly, Karen, Rahim, Faisal, Rahimi, Abdul H, Rahimi, Haseena R, Rahman, Muhammad, Rahman, Salim Ur, Rahmany, Sohail, Rai, Prajan, Rai, Sabi, Rai, Supriya, Raisova, Lenka, Raithatha, Ajay, Raj, Arjun, Rajagopal, Anithya, Rajagopalan, Pradeep, Rajaiah, Nithy, Rajalingam, Kanendran, Rajasekaran, Arvind, Rajasri, Aylur, Rajbhandari, Bibek, Rajbhandari, Sagar, Rajeswaran, Thurkka, Rajeswary, Jyothi, Rajkanna, Jeyanthy, Rajkumar, Indhuja, Rajmohan, Gayathri, Rallan, Ruth, Ralston, Katherine, Ralston, Maximilian, Ram, Matsa, Ramabhadran, Balaji, Ramali, Fathima, Ramali, Mohamed, Ramanan, Athimalaipet, Ramanna, Shashikira, Ramasamy, Maheshi, Rambe, Irfah, Ramchandani, Aradhana, Ramdin, Dhanishta, Ramirez, Jozel, Ramirez, Mylah, Ramnarain, Geshwin, Ramnarine, Amrita, Ramos, Lidia, Rampling, Tommy, Ramraj, Shanthi, Ramsay, Janine, Ramshaw, Alex, Rana, Aleem, Rana, Ghulam F, Rana, Naeem, Rana, Rehman, Rand, Abby, Rand, James, Randheva, Harpal, Ranga, Poonam, Rangar, Manmeet, Rangarajan, Harini, Ranjan, Sameer, Rank, Hannah, Ranka, Poormina, Rankhelawon, Rajesh, Rankin, Alastair, Rao, Anita, Rao, Sandhya, Rao, Sanjay, Rao, Deepak, Rasheed, Althaf A, Rashid, Khalid, Rason, Madeleine, Raspa, Valentina, Rastogi, Somil, Rasul, Fazila, Ratcliff, Simbisai, Ratcliffe, Sam, Ratcliffe, Sophy, Rath, Priti, Rath, Sanjeev, Rather, Mohmad I, Rathod, Krishnaraj, Rathore, Selina, Ratnakumar, Aravinden, Ratoff, Jonathan, Rattehalli, Deepa, Ravaccia, Davide, Raval, Malvi, Ravencroft, Phil, Raw, Jason, Raw, Rachael, Rawal, Manisha, Rawashdeh, Sulaiman A, Rawlins, Hywel, Ray, Gautam, Raymond-White, Adam, Raynard, Dana, Rayner, Helen, Rayner, Nicola, Raynsford, Amy, Razvi, Salman, Razvi, Zarine, Read, Kerry, Read, Sarah, Reay, Michael, Reddington, Anne, Reddy, Ajay, Reddy, Anvesh, Reddy, Harsha, Redfearn, Heidi, Redfern-Walsh, Aine, Redknap, Ianto, Redman, Nell, Redome, Alex, Redome, Joan, Reed, Anna, Reed, John, Rees, Andrew, Rees, Caitlin, Rees, Helen, Rees, James, Rees, Martyn, Rees, Sarah, Rees, Stephanie, Rees, Tabitha, Rees-Jones, Elinor, Regan, Fiona, Regan, Karen, Regan, Martin, Regan, Susan, Rege, Kanchan, Regmi, Amuda, Rehan, Ahmed, Rehman, A, Rehman, Hafiz, Rehman, Shoib, Rehman, Zainab, Reid, Ada, Reid, Andrew, Reid, Jennifer, Reid, Jeremy, Reid, Sharon, Reilly, Mkyla, Reilly, Sharon, Reith, Christina, Reka, Arisa, Remegoso, Alda, Rengan, Dinakaran, Renouf, Louise, Renshaw, Stephen, Renu Vattekkat, Remya, Reschreiter, Henrik, Revels, Mark, Revill, Adam, Rewitzky, Glynis, Rey, Severine, Reynard, Charles, Reynish, Dominic, Reynolds, Heather, Reynolds, Peter, Reynolds, Piero, Rhodes, Jonathan, Riaz, Naghma, Ribeiro, Patricia, Rice, Emily, Rice, Matthew, Rice, Natalie, Rich, Mel, Richards, Alex, Richards, Alison, Richards, Liz, Richards, Suzanne, Richardson, Celia, Richardson, Emma, Richardson, Fiona, Richardson, Jamie, Richardson, Julie, Richardson, Madeleine, Richardson, Neil, Richardson, Nicky, Riches, Joanne, Riches, Katie, Richmond, Leah, Richmond, Ruth, Ricketts, William, Rickman, Hannah, Riddell, Anna, Ridgway, Stephanie, Ridha, Mohamed, Ridley, Carrie, Ridley, Paul, Rieck, Gudrun, Rigby, Linsey, Rigby, Myckala, Rigler, Daniel, Rijal, Samita, Rika, Nur, Riley, Hannah, Riley, Matthew, Riley, Phil, Rimainar, Atika, Rimba, Zwesty V P, Rimmer, Dominic, Rina, Winarni, Rintoul, Robert, Riordan, Andrew, Ripley, David, Rippon, Naomi, Rishton, Chloe, Riste, Michael, Ritchie, David, Ritchie, Jane, Ritchings, Andy, Rivera Ortega, Pilar, Rivers, Vanessa, Rizvi, Batool, Rizvi, Syed A S, Rizvi, Syed H M, Robb, James, Robbins, Edel, Roberts, Charles, Roberts, Gareth, Roberts, Ian, Roberts, Jane, Roberts, Jean, Roberts, Karen, Roberts, Mark, Roberts, Nicky, Roberts, Philip, Roberts, Rebecca, Roberts, Victoria, Robertson, Calum, Robertson, James, Robertson, Jamie, Robertson, Kirsten, Robertson, Nichola, Robertson, Stuart, Robertson, Mhairi, Robin, Nicole, Robinson, Caroline, Robinson, Emma, Robinson, Gisela, Robinson, Hannah, Robinson, Jane, Robinson, Jemima, Robinson, Kate, Robinson, Liz, Robinson, Matthew, Robinson, Nicky, Robinson, Richard, Robinson, Ryan, Robinson, Sandra, Robinson, Alexandra, Robson, Steve, Rocca, Anna, Roche, Lisa, Roche, Samantha, Rodden, Natalie, Roddick, Alistair, Roddy, Elin, Roddy, Jack, Roderick, Marion, Rodger, Alison, Rodger, Faye, Rodger, Megan, Rodger, Michael, Rodgers, Alicia, Rodgers, Deirdre, Rodgers, Natasha, Rodgers, Penny, Rodriguez-Belmonte, Rocio, Roe, Nicholas, Roehr, Charles, Rogers, Gill, Rogers, Jason, Rogers, Joanne, Rogers, John, Rogers, Leigh, Rogers, Lindsay, Rogers, Michaela, Rogers, Paula, Rogers, Susan, Rogers, Thomas, Rojkova, Jana, Roka, Kshetra Kumari, Rokadiya, Sakib, Rollins, Lee, Rollo, Jennifer, Rolls, Catherine, Rond-Alliston, Alexander, Rook, Claire, Rooney, Kevin, Rooney, Lynsey, Rosaroso, Lace P, Rosby, Emily J, Rose, Abigail, Rose, Alastair, Rose, Annie, Rose, Steve, Rose, Zoe, Rosier, Josephine, Roskilly, Anna, Ross, Gavin A, Ross, Isobel, Ross, Jack, Rossdale, Jennifer, Ross-Parker, Andrew, Rostron, Anthony, Rosyid, Alfian Nur, Rothman, Alex, Rothwell, Joanne, Roughley, Lindsay, Rourke, Catherine A, Rowan, Kathryn, Rowan, Neil, Rowan, Stephen, Rowe, Anna, Rowe, Nicola, Rowe-Leete, Louise, Rowlands, Benjamin, Rowlands, Elen, Rowley, Megan, Roy, Subarna, Roycroft, Matthew, Roynon-Reed, Anna, Royson, Ann R, Rozewicz, Sam, Rudenko, Anna, Rudrakumar, Senthan, Rudran, Banu, Ruff, Shannon, Rughani, Prita, Rule, Rory, Rundell, Sharon, Rushforth, Eve, Rushmer, Jeremy, Rusk, Darren, Russell, Peter, Russell, Richard, Russo, Cristina, Rutgers, Marieke, Rutkowski, Krzysztof, Ryan, Aidan, Ryan, Brendan, Ryan, Kathryn, Ryan, Lucy, Ryan, Matthew, Ryan, Pat, Ryan, Phil, Ryan-Wakeling, Declan, Rybka, Elena, Ryder, Maggie, Ryder, Sophie, Saad, M, Saalmink, Gwendolyn, Sabale, Javeson, Sabaretnam, Suganya, Sadiq, Noman, Sadler, Emma, Saffy, Ashiq, Sage, Beth, Sagoo, Harkiran, Sagrir, Sobia, Saha, Rajnish, Saha, Sian, Sahdev, Nikhil, Sahedra, Sarvjit, Sahota, Jagdeep, Said, Nooria, Saini, Shalini, Saint, Bryony, Sajid, Anam, Sakthi, Sreekanth, Sakuri, Hikari, Saladi, Murthy, Salam, Abdul, Salberg, Armorel, Salciute, Erika, Saleeb, Gina, Saleh, Mumtaz, Salih, Hizni, Salih, Laylan, Salim, Duha, Salisbury, Sarah, Saliu, SiteEneye, Salman, Rustam, Salmon, Jenny, Salmon, Rebecca, Salutous, Dario, Sam, Mfon, Sam, Sally, Samakomva, Tinashe, Saman, Razan, Samar, Sakeena, Saminathan, Selva, Samlal, Renaldo, Sammons, Emily, Sammut, David, Sammut, Mark, Sammut, Saud, Sammut, Thomas, Sampath, Sunitha, Sampson, Claire, Sampson, Julia, Samson, Aashna, Samson, Anda, Samuel, Johnson, Samuel, Merna, Samuel, Reena, Samuel, Thomas D L, Samuel, Younan, Samuels, Kevin, Samuels, Theo, Samways, Joanna, Samyraju, Manjula, Sana, Ilves, Sanchez, Veronica, Sanchez Gonzalez, Amada, Sanda-Gomez, Alina, Sandercock, Peter, Sanders, Jack, Sanderson, Amy, Sanderson, Tom, Sandhu, Kuljinder, Sandhu, Loveleen, Sandow, Sam, Sandrey, Victoria, Sands, Sarah, Sanga, Langizya, Sangha, Harwinder, Sanghera, Jasmine, Sangombe, Mirriam, Sanju, Mathew, Sankaran, Lakshmi, Santos, Filipa, Santos Ferreira De Almeida, Catarina, Santosh, Rojy, Sanyal, Jayanta, Sanz-Cepero, Aureo F, Sapkota, Yunima, Saragih, Dan, Saralaya, Dinesh, Saraswati, Anggita, Saraswatula, Arun, Saravanamuthu, Pira, Sarella, Joshua, Sarfatti, Avishay, Sargent, Rebecca, Sari, Beatrix, Sari, Diah, Sarkar, Khatija, Sarkar, Rahuldeb, Sarma, Sruthi, Sarmiento, Paulo, Sarwar, Zainab, Sass, Thea, Satchithananthasivam, Krishna, Sathe, Sonia, Sathianandan, Sobitha, Sathyanarayanan, Abilash, Sathyanarayanan, Lavanya S J P, Sathyapalan, Thozhukat, Satodia, Prakash, Saulite, Vera, Saunders, Andrew, Saunders, Rachel, Saunders, Samantha, Saunderson, Anne, Savill, Heather, Savlani, Karishma, Saxena, Gauri, Saxton, Matthew, Sayan, Amrinder, Sayers, Ian, Scaletta, Diane, Scanlon, Deborah, Scanlon, Jeremy, Scarratt, Lyndsay, Scattergood, Sean, Schadenberg, Alvin, Schafers, Jenna, Schneblen, Wendy, Schofield, Ella, Schofield, Rebecca, Schofield, Samuel, Scholes, David, Scholes, Karen, Schoolmeesters, Alex, Schumacher, Natasha, Schunke, Nicola, Schuster Bruce, Martin, Schwarz, Karin, Scobie, Antonia, Scoones, Thomas, Scorrer, Tim, Scott, Alex, Scott, Alistair, Scott, Anne, Scott, Catherine, Scott, Christine, Scott, Emily, Scott, Kathyn, Scott, Leanne, Scott, Martha, Scott, Stephen, Scott, Timothy, Scott, Zoe, Scourfield, Sarah, Scrase, Wendy, Scriven, Nicholas A, Scullion, Angela, Scullion, Therese, Seager, Emily, Seagrave, Cathy, Seaman, Rebecca, Sear, Eleanor, Seaton, Isabella, Seatter, Annette, Seckington, Anna, Sedano, Joanna, Seddon, Gabrielle, Sedgwick, Gemma, See, Yee Yong, Seelarbokus, Muhammad A, Sefton, Christopher, Segovia, Matias, Seidu, Fatima, Sekadde, Gillian, Selby, Faye, Selby, Georgina, Sellar, Claire, Sellars, Rachael, Sellers, Katharine, Selley, Joseph, Sellick, Victoria, Selvadurai, Gobika, Selvarajah, Brintha, Selvaskandan, Haresh, Selvendran, Subothini S, Selwyn, Jeyakumar, Semmens, Alison, Semple, Gary, Sen, Michael, Sen, Nandini, Sen, Seema, Sengupta, Aditya, Sengupta, Niladri, Senra, Susana, Senya, HoJan, Serafimova, Teona, Sernicola, Elisa, Sethi, Dheeraj, Sethi, Shivam, Setty, Niranjan, Seward, Abigail, Sewdin, Teswaree, Sewell, Terri-Ann, Seymour, Jack, Seymour, Katherine, Shabbir, Hussam, Shackley, Fiona, Shafi, Tariq, Shafique, Faiza, Shah, Aashni, Shah, Ahmar, Shah, Anand, Shah, Bhavni, Shah, Hussun-Ara, Shah, Momin, Shah, Neil, Shah, Pallav, Shah, Priyank, Shah, Qasim, Shah, Rupal, Shah, Sarfaraz H, Shah, Snehal, Shah, Suraj, Shah, Syed, Shah, Wajid, Shahad, Saarma, Shahi, Sousan, Shahnazari, Sipan, Shahzad, Najam, Shahzeb, Muhammad, Shaibu, Aisha, Shaida, Zara, Shaikh, Amina Y, Shaikh, Maliha, Shail, Rajit, Shaji, Mariya, Shakeel, Muhammad, Shakya, Roshni, Shalan, Korah, Shamim, Nadia, Shamji, Ummulbaneen, Shams, Anindya, Shams, Kazi, Shamsah, Rasha, Shanahan, Thomas, Sharaf, Hamed, Sharif, Asir, Sharma, Ajay, Sharma, Ash, Sharma, Bhawna, Sharma, Mona, Sharma, Ojasvi, Sharma, Poonam, Sharma, Rajeev, Sharma, Sagar, Sharma, Sanjeev, Sharma, Sarkhara, Sharma, Seema D, Sharma, Shriv, Sharma, Sonal, Sharp, Alexander, Sharp, Charles, Sharp, Gemma, Sharp, Kerry, Sharp, Louise M, Sharratt, Paula, Sharratt, Phoebe, Sharrocks, Katherine, Shashaa, Serene, Shaw, Alexandra, Shaw, Christopher, Shaw, Daisy, Shaw, David, Shaw, Deborah, Shaw, Joanne, Shaw, Jonathon, Shaw, Lisa, Shaw, Michele, Shaw, Tomos G, Shawcross, Anna, Shawcross, James, Shawe, Jill, Shayler, Lou, Shedwell, Sophy, Sheffield, Jonathan, Shehata, Zak, Sheik, Arshiya, Sheikh, Asif, Sheikh, Noorann, Shelley, Benjamin, Shelton, Sarah, Shenoy, Anil, Shenton, Julie, Shephardson, Sarah, Shepherd, Amy, Shepherd, Kate, Shepherd, Lorna, Shepherd, Scott, Sheppard, Gareth, Sheppeard, Rhian, Sheridan, Helen, Sheridan, Ray, Sherridan, Samuel, Sherris, Leanne, Sherwin, Susanna, Shibly, Shaad, Shiham, Fathimath F, Shilladay, Cassandra, Shillitoe, Ben, Shingadia, Delane, Shioi, Chiaki, Shirgaonkar, Anand, Shirley, Kim, Shirt, Helen, Shonubi, Adebusola, Shoote, Jane, Shorrocks, Ruth, Shortman, Rob, Shotton, Rohan, Shotton, Sarah, Shovelton, Charmaine, Shpuza, Ervin, Shrestha, Anil, Shrestha, Apurba, Shrestha, Nora, Shrestha, Reema, Shrestha, Suchita, Shuker, Karen, Shurlock, Jonathan, Shurmer, Jack, Shuvo, Erfanur R, Siame, Gilbert, Siamia, Loria, Siaw-Frimpong, Moses, Siddavaram, Seshnag, Siddique, Nasir, Siddique, Shahla, Siddique, Sohail, Siddle, Elaine, Sidebotham, Emma, Sidebottom, Jo, Sievers, Roy, Siggens, Katie, Sikondari, Nyma, Silanas, Ilman, Silva, Sofia V, Silva Moniz, Claudia, Sim, Malcolm, Simangan, Theresa, Simbi, Vimbai, Sime, Robert, Simmons, George, Simmons, Oliver, Simms, Richard, Simon, Laura, Simon, Merritt, Simon, Natalie, Simpkins, Samantha, Simpson, Angela, Simpson, Anna, Simpson, Danny, Simpson, Georgina, Simpson, Joanne, Simpson, Kerry, Simpson, Maria, Simpson, Phillip, Simpson, Thomas, Simpson, Kathryn, Sinclair, Simon, Sing, Cindy, Singh, Ankita, Singh, Claire, Singh, Davinder, Singh, Jayaprakash, Singh, Jyoti, Singh, Lokeshwar, Singh, Manjeet, Singh, Nadira, Singh, Pankaj, Singh, Prabhsimran, Singh, Salil, Singh, Saurabh, Singh, Shivani, Singh, Sumi, Singhal, Parag, Singizi, Bryan, Singler, Vicky, Sinha, Manas, Sinha, Punam, Sinha, Sharad, Sinha, Utkarsh, Sisson, Guy, Sithiravel, Sarah, Sivakumar, Karthikadevi, Sivakumar, Shanmugasundaram, Sivakumran, Darsh, Sivanadarajah, Sivanthi, Sivasothy, Pasupathy-Rajah, Skaria, Asok, Skehan, Nicole, Skelly, Robert, Skelton, Orlagh, Skene, Imogen, Skinner, Denise, Skinner, Tabitha, Skinner, Victoria, Skorko, Agnieszka, Skorupinska, Iwona, Skorupinska, Mariola, Slack, Amy, Slack, Katie, Slade, Heather, Slade, Mark, Slater, Lynda, Slawson, Nicola, Slingsby, Rachel, Sloan, Andrew, Sloan, Brendan, Sloan, Derek, Sloane, Geraldine, Slowinska, Malgorzata, Small, Benjamin, Small, Ellen, Small, Samuel, Smallridge, Adam, Smalls, Dawn, Smallshaw, Karen Denise, Smallwood, Andy, Smart, Brittany, Smart, Lynne, Smeaton, Justyna, Smit, Carien, Smith, Aileen, Smith, Alex, Smith, Amanda, Smith, Amy, Smith, Andrew, Smith, Catherine, Smith, Chris, Smith, Christopher, Smith, Coral, Smith, Debra, Smith, Dominic, Smith, Eleanor, Smith, Harriet, Smith, Hazel, Smith, Helen, Smith, Jacky, Smith, Jessica, Smith, Kate, Smith, Kerry, Smith, Lara, Smith, Linda, Smith, Lisa, Smith, Loren, Smith, Maria, Smith, Mark, Smith, Martha A, Smith, Mel, Smith, Nicholas, Smith, Oliver, Smith, Philippa, Smith, Rachel, Smith, Rebecca, Smith, Rheanna, Smith, Richard, Smith, Sally, Smith, Samantha, Smith, Stacey, Smith, Stephanie, Smith, Susan, Smith, Tracy, Smith, Victoria, Smith, Imogen, Smith, John, Smolen, Sue, Smuts, Sara, Smyth, Naoise, Snell, Annette, Snell, David, Snell, Luke, So, Alfred, So, Beng, Soan, Michelle, Sobande, Toluleyi, Sobowiec Kouman, Sonia, Sobrino Diaz, Alberto, Sohail, Basit, Sohail, Bina, Sohal, Herminder, Soiza, Roy, Solademi, Olajumoke, Soleimani, Babak, Solesbury, Amanda, Soliman, Mohamed, Solis, Bernadette, Solly, Reanne, Solomon, Louise, Somalanka, Subash, Somashekar, Chandrashekaraiah, Sommerfield, Sven, Soni, Govind, Sonia, Raj, Sonoiki, Temi, Soo, Shiu-Ching, Soor, Pavandeep, Soothill, Germander, Soren, Jennifer, Sothinathan, Apina, Sothirajah, Pragalathan, Sousa, Jessica, Soussi, Najwa, Southam, Donna, Southern, David, Southern, Iain, Southern, Louise, Southin, Sara M, Southwell, Jessica, Southworth, Thomas, Sowden, Sandra, Sowter, Jason, Spalding, Claudia, Spata, Enti, Speare, Catherine, Spears, Katie, Spears, Mark, Speirs, Lynne, Speirs, Susan, Spence, Michelle, Spence, Niamh, Spencer, Branwell, Spencer, Gisele, Spencer, Rebecca, Spencer, Sue, Spencer, Tom, Spickett, Helen, Spillane, Jennifer, Spiller, William, Spinks, Kerry, Spinks, Michelle, Spittle, Nick, Spray, Sarah, Spriggs, Janet, Spring, Oliver, Squires, Gemma, Squires, Jack, Squires, Rebecca, Sreenivasan, Ram, Sreenivasan, Shiva, Sri Paranthamen, K, Srikantaiah, Rajesh, Srinivasan, Koottalai, Srinivasan, Ramesh, Srirajamadhuveeti, Asha, Srirathan, Vino, Stacey, Rhodri, Stacpoole, Sybil, Stadon, Louise, Stagg, William J, Staines, Jocasta, Staines, Nikki, Stammers, Katie, Stanciu, Roxana, Stanczuk, Grazyna, Standley, Thomas, Staniforth, Brittany, Stanton, Andrew, Stanton, Lisa, Staples, Robyn, Stapley, Simon, Staplin, Natalie, Stark, Adam, Starkey, Elizabeth, Starnes, David S, Starr, Michelle, Stead, Rachel, Stebbing, Clare, Steele, Conor, Steer, Henry, Steer, John, Stefania, Vergnano, Stefanowska, Paula, Steffensen, Femke, Stemp, Caroline, Stenson, Emma, Stephens, Alison, Stephensen, David, Stephenson, Elaine, Sterrenburg, Monique, Stevens, Jennifer, Stevens, Melanie, Stevens, Will, Stevenson, Amy, Stevenson, Andrew, Stevenson, Lesley, Stevenson, Sarah, Steward, Matthew, Stewart, Christopher, Stewart, Claire, Stewart, Colin, Stewart, Dobree A, Stewart, Katelyn, Stewart, Keely, Stewart, Kristina, Stewart, McKenna, Stewart, Melissa, Stewart, Rachel, Stewart, Richard, Stickley, Jo, Stiller, Gemma, Stirrup, Sarah, Stock, Sarah, Stockdale, Alexander, Stocker, Danielle, Stockham, Lynne, Stockton, Paul, Stoddard, Emma, Stoffberg, Kevin, Stokes, Chelsea, Stokes, Chris, Stone, Ben, Stone, Roisin, Stone, Sarah, Stoner, Emma-Jane, Storey, Imogen, Storton, Kim, Stourton, Frederick, Strachan, Angela, Strait, Catherine, Stratton, Emma, Stratton, Jane, Straw, Sam, Streit, Dieter, Stride, Emma, Stringer, Sally, Strong-Sheldrake, Sophia, Struik, Siske, Stuart, Carmel, Stubbs, Anna, Stubbs, Harrison, Sturdy, Ann, Sturney, Sharon, Stuttard, Matt, Suarez, Cristina, Subba, Karuna, Subbe, Christian P, Subramaniam, Keerth, Subramanian, Manjula, Subramanian, Vaidyanathan, Subramanian, Venkatram, Subudhi, Chinari, Suckling, Rebecca, Sudershan, Srivatsan, Sugden, Peter, Suherman, Putri A, Sukla, Rudresh, Sukumaran, Anila, Suleiman, Ezoubi, Suliman, Ali, Suliman, Fatimah, Sultan, Sugrah, Sumardi, Uun, Sundar, Samyukta, Sundaram, Radha, Sundhar, Reka, Sung, Edmond, Sunni, Nadia, Suntharalingam, Jay, Sur, Amitava, Suresh, Dharmic, Suresh, Nayanika, Suresh, Shilpa, Surtees, Michael, Susan, C, Suter, Danielle, Suthar, Rohan, Sutherland, Helen, Sutherland, Rachel, Sutherland, Rebecca, Sutherland, Sara-Beth, Sutinyte, Dovile, Sutton, Deborah, Sutton, Sam, Sutton, Siobhan, Sutu, Mihaela, Svensson, Marie-Louise, Svirpliene, Sima, Swain, Andrew, Swain, Rose, Swaine, Thomas, Swales, Christopher, Swanson-Low, Carla, Swart, Tirion, Sweetman, Stephen, Swift, Ealish, Swift, Paul, Swift, Pauline, Swift, Rachael, Swingler, Rachel, Swinhoe, Sophie, Swist-Szulik, Katarzyna, Swithenbank, Luke, Syed, Omair, Sykes, Catriona, Sykes, Daisy, 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A, Taylor, David, Taylor, Elisabeth, Taylor, Holly, Taylor, Janet, Taylor, Jennifer, Taylor, Joanne, Taylor, Julie, Taylor, Karen, Taylor, Leanne, Taylor, Margaret, Taylor, Matthew, Taylor, Melanie, Taylor, Natalie, Taylor, Rachael, Taylor, Rachel, Taylor, Samantha, Taylor, Suzanne, Taylor, Tracey, Taylor, Vicky, Taylor, Victoria, Taylor-Siddons, Michelle, Taynton, Thomas, Te, Amelia, Teasdale, Francesca, Teasdale, Jessica, Teasdale, Katherine, Tebbutt, Julie, Tee, Caroline, Teeluck, Izla, Tejero Moya, Borja, Tejwani, Rajni, Telfer, Adam, Teli, Vibha, Tempany, Jennifer, Temple, Julie, Temple, Natalie, Tench, Helen, Teoh, Yi He, Tereszkowski-Kaminski, Radoslaw, Terrett, Lynne, Terry, Louise, Tesha, Tesha Islami Monika, Tetla, Dariusz, Tewari, Shirish, Tewkesbury, Daniel, Texeira, Joana, Tey, ChiaLing, Thake, Miriam, Thakker, Clare, Thakker, Manish, Thakrar, Jayna, Thakuri, Bishal Jung, Thamu, Bhavneet, Thao, Nguyen Thi, Thapa, Amita, Thatcher, Hilary, Thayanandan, Andrew, Thazhatheyil, 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Tulus Satriasih, Tulus, Tunesi, Grace, Turbitt, Killiam, Turel, Rezon, Turgut, Tolga, Turley, Claudia, Turnbull, Alison, Turner, Aine, Turner, Ash, Turner, Charlotte, Turner, Gail, Turner, Georgina, Turner, Kate, Turner, Kelly, Turner, Kim, Turner, Lucy, Turner, Lynne C, Turner, Mark, Turner, Patricia, Turner, Sally, Turner, Samantha, Turner, Sarah, Turner, Victoria, Turner-bone, Ian, Turney, Sharon, Turvey, Jon, Tweed, Conor, Tweed, David, Twemlow, Rebecca, Twohey, Emma, Tyagi, Bhavya, Tyagi, Vedang, Tyer, Abigail, Tyler, Amanda, Tyler, Jayne, Tyler, Jennifer, Tyzack, Alison, Tzavaras, Petros, Tzinieris, Ioannis, Uddin, A Wahid, Uddin, Mohammad S, Uddin, Ruhama, Uddin, Ruzena, Ugoji, Jacinta, Ukaegbu, Edith N, Ul Haq, Mazhar, Ul Hassan, Waqar, Ul-Haq, Zia, Ullah, Salamat, Ullah, Sana, Ullah, Sanda, Um, Ju, Umaipalan, Athavan, Umate, Anil, Umeadi, Judith, Umeh, Akudo, Umeojiako, Wilfred, Ummat, Ben, Underhill, Emma, Underwood, Charlotte, Underwood, Jonathan, Unsworth, Adam, Uppal, Veerpal, Uppal, Veerpal S, Upson, Gerry, Ur Rasool, Masood, Uriel, Alison, Urruela, Sebastian, Uru, Hiromi, Usher, Jess, Usher, Miranda, Usher, Rebecca, Usher-Rea, Alexandra, Ustianowski, Andrew, Usuf, Effua, Utomo, Febriansyah Nur, Uzu, Hiromi, Vaccari, Linda C, Vaghela, Uddhav, Vaidya, Abhay, Vail, Denny, Valecka, Bernardas, Valentine, Jennifer, Valeria, Balan, Vallabhaneni, Pramodh, Vallotton, Nick, Vamplew, Luke, Vamvakiti, Ekaterini, Vamvakopoulos, Joannis, Van Blydenstein, Sarah, van Bruggen, Lucia, van de Venne, Maud, van der Meer, Alex, van der Stelt, Nora, van Koutrik, Lynne, Van Loggerenberg, Alexander, Vance-Daniel, Joseph, Vancheeswaran, Rama, Vandeyoon, Samuel I, Vankayalapati, Padma, Vanmali, Piyush, Vansomeren, Chloe, Van't Hoff, William, Vara, Sejal, Vardy, Stehen J, Varghese, Anu, Varghese, Maria, Varney, William, Varnier, Giulia, Varouxaki, Anna-Nektaria, Varquez, Resti, Vasadi, Valeria, Vass, Olivia, Vassell, Katherine, Vasu, Vimal, Vasudevan, Vasanthi, Vatish, Manu, 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Vivekananthan, Sankkita, Vlad, Elena, Vlies, Ben, von Oven, Linda, Vooght, Claire, Vu Thai, Kim Thi, Vutipongsatorn, Kritchai, Vuylsteke, Alain, Vyras, Eleftheria, Wach, Richard, Wadams, Beverley, Wadd, Susan, Waddington, Natalia, Wade, Phillip, Wadsley, Jonathan, Wadsworth, Kirsten, Wafa, Syed E I, Wagstaff, Daniel, Wagstaff, Lynda, Wahab, Dalia, Wahbi, Zaroug, Waheed Adigun, Abiodun, Waidyanatha, Sawan, Waite, Alicia, Wake, Rachel, Wakefield, Alice, Wakeford, William, Wakinshaw, Fiona, Waldeck, Emma, Walden, Andrew, Walding, Lorna, Waldron, Alexandria, Waldron, Joanne, Wales, Emma, Wali, Batool, Walker, Danielle, Walker, Gemma, Walker, Harriet, Walker, Ian, Walker, Kevin, Walker, Kim, Walker, Lauren, Walker, Linda, Walker, Lynne, Walker, Olivia, Walker, Rachel, Walker, Rebecca, Walker, Sara, Walker, Susan, Wallace, Gillian, Wallbutton, Rebecca, Wallen, Jessica, Wallendszus, Karl, Waller, Arabella, Waller, Rosemary, Wallis, Gabiel, Wallis, Gabriel, Wallis, Louise, Wallis, Matthew, Walmsley, Emma, Walsh, Donna, Walsh, Elizabeth, Walsh, Livia, Walstow, Deborah, Walter, Daniel, Walters, Alex, Walters, Holt, Walters, James, Walters, Jocelyn, Walton, Eileen, Walton, Lucy, Walton, Maisie, Walton, Michael, Walton, Olivia, Walton, Sharon, Walton, Susan, Wan, Mandy, Wanda, Junita, Wands, Mary, Wane, Rachel, Wang, Frank, Wang, Nick, Wang, Ran, Wang, Shentong, Warbrick, Deborah, Warburton, Samantha, Ward, Christopher, Ward, Deborah, Ward, Emma, Ward, Hannah, Ward, Janice, Ward, Joanna, Ward, Luke, Ward, Nicola, Ward, Rachael, Ward, Thomas, Ward, Tom, Warden, Scott A, Wardere, Gibril, Wardle, Steve, Wardy, Hassan, Waring, Gareth, Waring, Scott, Warmington, Jenny, Warner, Ben, Warner, Christian, Warnock, Lewis, Warran, Sarah, Warren, Jade, Warren, Lisa, Warren, Rebecca, Warren, Yolanda, Warrender, Davina, Warren-Miell, Hannah, Warris, Adilia, Warwick, Gill, Wassall, Helen, Wasserman, Sean, Wasson, Elizabeth, Watchorn, Hazel J, Waterfall, Holly, Waters, Abby, Waters, Donald, Waterstone, Mark, Watkin, Abigail, Watkins, Catherine, Watkins, Catrin, Watkins, Eleanor, Watkins, Karen, Watkins, Lynn, Watson, Abigail, Watson, Adam J R, Watson, Ekaterina, Watson, Eleanor, Watson, Felicity, Watson, J G R, Watson, Louisa, Watson, Paul, Watson, Rebecca, Watson, Robert, Watson, Kathleen, Watters, Malcolm, Watterson, Donna, Wattimena, Khairiah, Watts, Daniel, Watts, John, Watts, Merlin, Waugh, Victoria, Wayman, Emma, Wayman, Matthew, Wazir, Akhlaq, Weatherhead, Mark, Weatherly, Nick, Webb, Chloe, Webb, Claire, Webb, Hayley, Webb, Kathryn, Webb, Kylie, Webb, Stephen, Websdale, Cheryl, Webster, Deborah, Webster, Ian, Webster, Jemma, Webster, Tim, Wedlin, Jordan, Wee, Ling, Weerakoon, Rebecca, Weerasinghe, Thanuja, Weeratunga, Janaka, Weetman, Maria, Wei, Shuying, Weichert, Immo, Welch, Emma, Welch, Hugh, Welch, James, Welch, Leanne, Welch, Steven, Welham, Benjamin, Weller, Samantha, Wellings, Lucy, Wells, Brian, Wellstead, Susan, Welsh, Berni, Welsh, Richard, Welters, Ingeborg, Welton, Rachael, Wenn, Victoria, Wentworth, Lauren, Wesonga, Joan, Wesseldine, Kate, West, Joe, West, Magdelena, West, Raha, West, Ruth, West, Sophie, Western, Luke, Westhead, Ruth, Weston, Heather, Westwood, Alice, Westwood, Kelly, Westwood, Sharon, Wetherill, Bill, Wheaver, Sharon, Wheeler, Helen, Whelan, Ben, Whelband, Matthew, Whileman, Amanda, Whitcher, Alison, White, Andrew, White, Ayesha, White, Benjamin, White, Catherine, White, Christopher, White, Duncan, White, James, White, Jonathan, White, Katie, White, Marie, White, Nick, White, Nikki, White, Sarah, White, Sonia, White, Tracey, Whitehead, Catherine, Whitehorn, Kelly, Whitehouse, Anne, Whitehouse, Claire, Whitehouse, Tony, Whiteley, Julia, Whiteley, Louiza, Whiteley, Sophie, Whitham, Rachael, Whitlingum, Gabriel, Whitmore, David, Whittaker, Elizabeth, Whittam, Lindsay, Whittington, Ashley, Whittle, Helen, Whittle, Robert, Wiafe, Eunice, Wiblin, Lou, Wickens, Olivia, Widdrington, John, Wieboldt, Jason, Wieringa, Hannah, Wiesender, Cornelia, Wiffen, Laura, Wight, Andrew, Wignall, Ashleigh, Wignall, Christopher, Wilce, Annamaria, Wilcock, Danielle, Wilcock, Emma, Wilcox, Louise, Wild, Ben, Wild, Laura, Wild, Stephen, Wilde, Michael, Wilding, Laura, Wilding, Peter, Wildsmith, Tracey, Wileman, Joe, Wiles, Joy, Wiles, Kate, Wilhelmsen, Elva, Wiliams, Thomas, Wilkie, Janet, Wilkin, David, Wilkins, Hannah, Wilkins, Joy, Wilkins, Suzanne, Wilkinson, Iain, Wilkinson, Lesley, Wilkinson, Nicola, Wilkinson, Sophia, Wilkinson, Susan, Wilkinson, Tim, Willetts, Sylvia, Williams, Aimee, Williams, Alexandra, Williams, Alison, Williams, Angharad, Williams, Anna, Williams, Ava, Williams, Carl, Williams, Caroline V, Williams, Claire, Williams, Dewi, Williams, Eleri, Williams, Gail, Williams, Gemma, Williams, Gina, Williams, Hannah, Williams, Heledd, Williams, James, Williams, Jennie, Williams, Jill, Williams, John, Williams, Joseph, Williams, Karen, Williams, Kathryn, Williams, Mandy, Williams, Marie, Williams, Mark, Williams, Matthew, Williams, Patricia, Williams, Penny, Williams, Rachel, Williams, Robin, Williams, Rupert, Williams, Samson, Williams, Sarah, Williams, Sophie, Williams, Steffan, Williams, Tamanna, Williams, Tania, Williamson, Annie, Williamson, Cath, Williamson, Catherine, Williamson, Dawn, Williamson, James D, Williamson, Jodie, Williamson, Rachel, Williamson, Helen, Willis, Elaine, Willis, Elizabeth, Willis, Emily, Willis, Heather, Willis, Herika, Willis, Joanna, Wills, Louise, Willsher, Lucy, Willshire, Catherine, Willson, Francesca, Willson, Jayne, Wilson, Alison, Wilson, Andrea, Wilson, Anna, Wilson, Antoinette, Wilson, Billy, Wilson, David, Wilson, Imogen, Wilson, James, Wilson, Karen, Wilson, Kate, Wilson, Kristy-Ann, Wilson, Lucinda, Wilson, Mark, Wilson, Stephen, Wilson, Toni, Wilson, John, Win, Khin Lei Yee, Win, Marlar, Win, Than, Win, Tin Tin, Win, Wut Yee Win, Winckworth, Lucinda, Winder, Laura, Winder, Piers, Winearl, Stuart, Winmill, Helen, Winn, Simon, Winpenny, Carmen, Winslow, Helen, Winter, Helen, Winter, Jonathan, Winter-Goodwin, Barbara, Winterton, Joseph, Winwood, Hannah, Wischhusen, Jack, Wisdom, Stephen, Wise, Matthew, Wiselka, Martin, Wiseman, Rebecca, Wiseman, Sophie, Wishart, Steven, WIshlade, Tabitha, Witele, Eric, Withers, Nicholas, Wittes, Janet, Wixted, Donna, Wodehouse, Therese, Wolf, Will, Wolff, Nicola, Wolffsohn, Kirsten, Wolf-Roberts, Rebecca, Wolodimeroff, Elena, Wolstencroft, Adam, Wong, Alan, Wong, Charlotte, Wong, Chi-Hung, Wong, Chi-Man, Wong, Edwin, Wong, Jessica S Y, Wong, Kit Y, Wong, Mei Yin, Wong, Nick, Wong, Sam, Wong, Ting, Wongkyezeng, Aaron B, Wood, Amanda, Wood, Caroline, Wood, Dianne, Wood, Fiona, Wood, Gordon, Wood, Hannah, Wood, Jennifer, Wood, Joe, Wood, Lisa, Wood, Louise, Wood, Madeleine, Wood, Stephen, Wood, Tracy, Woodall, Katharine, Woodfield, Rebecca, Woodford, Christopher, Woodford, Elizabeth, Woodford, Jill, Woodhead, Louise, Woodhead, Timothy, Woodland, Philip, Woodman, Marc, Woodman, Myles, Woodmansey, Stephen, Woods, Charlotte, Woods, Jane, Woods, Katherine, Woods, Sarah, Woodward, Zoe, Woolcock, Megan, Wooldridge, Gemma, Woolf, Rebecca, Woollard, Chris, Woollard, Christopher, Woollen, Louisa, Woolley, Emma, Woolley, Jade, Woosey, Daniel, Wootton, Dan, Wootton, Joanne, Worley, Daniel, Worton, Stephy, Wraight, Jonathan, Wray, Maria, Wren, Kim, Wren, Lynn, Wrey Brown, Caroline, Wright, Catherine, Wright, Demi, Wright, Francesca, Wright, Holly, Wright, Imogen, Wright, Lianne, Wright, Rachel, Wright, Sarah, Wright, Stephanie, Wright, Tim, Wroe, Caroline, Wroe, Hannah, Wu, Henry, Wu, Peishan, Wu, Pensee, Wubetu, Jonathan, Wulandari, Fitria, Wulandari, Retno, Wurie, Subie, Wyatt, Craig, Wyn-Griffiths, Frederick, Wynter, Inez, Xavier, Bindhu, Xhikola, Arnold, Xia, Bingru E, Xia, Zhongyang, Yacoba, Effua, Yadav, Santosh, Yakubi, Masseh, Yan, May, Yanagisawa, Yuuki, Yang, Freda, Yang, Yingjia, Yanney, Michael, Yap, Woei Lin, Yaqoob, Nabil, Yasmin, Salima, Yates, Bryan, Yates, David, Yates, Edward, Yates, Helen, Yates, Thomas, Yates, Mark, Ye, Jessica, Yearwood Martin, Charlotte, Yein, Khin, Yelnoorkar, Fiona, Yen, Lam Minh, Yeoh, Alastair, Yeung, Chun Yu, Yew, Peter, Yewatkar, Durgesh, Ylquimiche Melly, Laura, Ynter, Inez, Yong, H, Yorke, Jemma, Youens, Jasmine, Younes Ibrahim, Abdel, Young, Eoin, Young, Gail, Young, Louise, Yousafzar, Asfand, Youssouf, Sajeda, Yousuf, Ahmed, Yovita, Hartantri, Yu, Chrissie, Yuan, Jack S J, Yufaniaputri, Nindya, Yung, Bernard, Yusef, Daniel, Yusef, Said, Yusuf, Intekhab, Zafar, Anna-Sophia, Zagalo, Silvia, Zaher, Su, Zahoor, Aqsa, Zainab, Mahrukh, Zak, Thornton, Zaki, Kareem, Zakir, Nabhan, Zalewska, Kasia, Zamalloa, Ane, Zaman, Mohsin, Zaman, Shakir, Zamikula, Julie, Zammit, Louise, Zammit-Mangion, Marie, Zawadzka, Marcelina, Zayed, Mohammed, Zebracki, Esther, Zehnder, Daniel, Zeidan, Lisa, Zeinali, Darius, Zhang, Jing, Zhao, Xiaobei, Zheng, Dongling, Zhu, Doreen, Zia, Madiha, Zibdeh, Omar, Zill-E-Huma, Rabia, Zin, Ei Thankt, Zincone, Eva, Zindoga, Garikai, Zinkin, Eleanor, Zinyemba, Vivian, Zipitis, Christos, Zitter, Letizia, Zmierczak, Arkadiusz, Zubikarai, Garazi, Zubir, Azam, Zuhra, Naz, Zulaikha, Rasha, Zulfikar, Sabrina, Zullo, Carol, and Zuriaga-Alvaro, Ana
Published: 2023
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40. Differential impact of tumor suppressor gene (TP53, PTEN, RB1) alterations and treatment outcomes in metastatic, hormone-sensitive prostate cancer

Author: Velez, Miguel Gonzalez, Kosiorek, Heidi E., Egan, Jan B., McNatty, Andrea L., Riaz, Irbaz B., Hwang, Steven R., Stewart, Glenn A., Ho, Thai H., Moore, Cassandra N., Singh, Parminder, Sharpsten, Renee K., Costello, Brian A., and Bryce, Alan H.
Published: 2022
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41. Intracellular Cardiac Signaling Pathways Altered by Cancer Therapies

Author: Scott, Shane S., Greenlee, Ashley N., Schwendeman, Ethan J., Mohammad, Somayya J., Naughton, Michael T., Matzko, Anna, Diallo, Mamadou, Stein, Matthew, Revan, Rohith, Zaramo, Taborah Z., Shimmin, Gabriel, Tarun, Shwetabh, Ferrall, Joel, Ho, Thai H., Smith, Sakima A., Parinandi, Narasimham L., editor, and Hund, Thomas J., editor
Published: 2022
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42. Face Generation from Skull Photo Using GAN and 3D Face Models

Author: Vo, Duy K., primary, Bui, Len T., additional, and Le, Thai H., additional
Published: 2022
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43. Quantitative Spatial Profiling of PD-1/PD-L1 Interaction and HLA-DR/IDO-1 Predicts Improved Outcomes of Anti-PD-1 Therapies in Metastatic Melanoma.

Author: Johnson, Douglas B, Bordeaux, Jennifer, Kim, Ju Young, Vaupel, Christine, Rimm, David L, Ho, Thai H, Joseph, Richard W, Daud, Adil I, Conry, Robert M, Gaughan, Elizabeth M, Hernandez-Aya, Leonel F, Dimou, Anastasios, Funchain, Pauline, Smithy, James, Witte, John S, McKee, Svetlana B, Ko, Jennifer, Wrangle, John M, Dabbas, Bashar, Tangri, Shabnam, Lameh, Jelveh, Hall, Jeffrey, Markowitz, Joseph, Balko, Justin M, and Dakappagari, Naveen
Subjects: Cell Line, Tumor, Humans, Melanoma, Neoplasm Metastasis, HLA-DR Antigens, Biopsy, Neoplasm Staging, Prognosis, Treatment Outcome, Retreatment, Immunohistochemistry, Protein Binding, Models, Biological, Adult, Aged, Middle Aged, Female, Male, Indoleamine-Pyrrole 2, 3, -Dioxygenase, Programmed Cell Death 1 Receptor, Biomarkers, Tumor, Antineoplastic Agents, Immunological, B7-H1 Antigen, Cancer, Prevention, Clinical Research, 2.1 Biological and endogenous factors, Aetiology, 4.2 Evaluation of markers and technologies, Detection, screening and diagnosis, Oncology and Carcinogenesis, Oncology & Carcinogenesis
Abstract: Purpose: PD-1/L1 axis-directed therapies produce clinical responses in a subset of patients; therefore, biomarkers of response are needed. We hypothesized that quantifying key immunosuppression mechanisms within the tumor microenvironment by multiparameter algorithms would identify strong predictors of anti-PD-1 response.Experimental Design: Pretreatment tumor biopsies from 166 patients treated with anti-PD-1 across 10 academic cancer centers were fluorescently stained with multiple markers in discovery (n = 24) and validation (n = 142) cohorts. Biomarker-positive cells and their colocalization were spatially profiled in pathologist-selected tumor regions using novel Automated Quantitative Analysis algorithms. Selected biomarker signatures, PD-1/PD-L1 interaction score, and IDO-1/HLA-DR coexpression were evaluated for anti-PD-1 treatment outcomes.Results: In the discovery cohort, PD-1/PD-L1 interaction score and/or IDO-1/HLA-DR coexpression was strongly associated with anti-PD-1 response (P = 0.0005). In contrast, individual biomarkers (PD-1, PD-L1, IDO-1, HLA-DR) were not associated with response or survival. This finding was replicated in an independent validation cohort: patients with high PD-1/PD-L1 and/or IDO-1/HLA-DR were more likely to respond (P = 0.0096). These patients also experienced significantly improved progression-free survival (HR = 0.36; P = 0.0004) and overall survival (HR = 0.39; P = 0.0011). In the combined cohort, 80% of patients exhibiting higher levels of PD-1/PD-L1 interaction scores and IDO-1/HLA-DR responded to PD-1 blockers (P = 0.000004). In contrast, PD-L1 expression was not predictive of survival.Conclusions: Quantitative spatial profiling of key tumor-immune suppression pathways by novel digital pathology algorithms could help more reliably select melanoma patients for PD-1 monotherapy. Clin Cancer Res; 24(21); 5250-60. ©2018 AACR.
Published: 2018

44. Intracellular Signaling Pathways Mediating Tyrosine Kinase Inhibitor Cardiotoxicity

Author: Scott, Shane S., Greenlee, Ashley N., Matzko, Anna, Stein, Matthew, Naughton, Michael T., Zaramo, Taborah Z., Schwendeman, Ethan J., Mohammad, Somayya J., Diallo, Mamadou, Revan, Rohith, Shimmin, Gabriel, Tarun, Shwetabh, Ferrall, Joel, Ho, Thai H., and Smith, Sakima A.
Published: 2022
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45. MTAP deficiency creates an exploitable target for antifolate therapy in 9p21-loss cancers

Author: Alhalabi, Omar, Chen, Jianfeng, Zhang, Yuxue, Lu, Yang, Wang, Qi, Ramachandran, Sumankalai, Tidwell, Rebecca Slack, Han, Guangchun, Yan, Xinmiao, Meng, Jieru, Wang, Ruiping, Hoang, Anh G., Wang, Wei-Lien, Song, Jian, Lopez, Lidia, Andreev-Drakhlin, Alex, Siefker-Radtke, Arlene, Zhang, Xinqiao, Benedict, William F., Shah, Amishi Y., Wang, Jennifer, Msaouel, Pavlos, Zhang, Miao, Guo, Charles C., Czerniak, Bogdan, Behrens, Carmen, Soto, Luisa, Papadimitrakopoulou, Vassiliki, Lewis, Jeff, Rinsurongkawong, Waree, Rinsurongkawong, Vadeerat, Lee, Jack, Roth, Jack, Swisher, Stephen, Wistuba, Ignacio, Heymach, John, Wang, Jing, Campbell, Matthew T., Efstathiou, Eleni, Titus, Mark, Logothetis, Christopher J., Ho, Thai H., Zhang, Jianjun, Wang, Linghua, and Gao, Jianjun
Published: 2022
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46. ZMYND8 preferentially binds phosphorylated EZH2 to promote a PRC2-dependent to -independent function switch in hypoxia-inducible factor–activated cancer

Author: Tang, Bo, Sun, Rui, Wang, Dejie, Sheng, Haoyue, Wei, Ting, Wang, Liguo, Zhang, Jun, Ho, Thai H., Yang, Lu, Wei, Qiang, and Huang, Haojie
Published: 2021

47. Identification of a CD4+ T cell line with Treg-like activity

Author: Ho, Thai H., Pfeffer, Kirsten, Weiss, Glen J., Ruiz, Yvette, and Lake, Douglas F.
Published: 2022
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48. Immune Therapies for Metastatic Kidney Cancer

Author: Faraj, Kassem S., Ho, Thai H., Tyson, Mark D., Castle, Erik P., Trabulsi, Edouard J., editor, Lallas, Costas D., editor, and Lizardi-Calvaresi, Anne E., editor
Published: 2021
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49. The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

Author: Ricketts, Christopher J, De Cubas, Aguirre A, Fan, Huihui, Smith, Christof C, Lang, Martin, Reznik, Ed, Bowlby, Reanne, Gibb, Ewan A, Akbani, Rehan, Beroukhim, Rameen, Bottaro, Donald P, Choueiri, Toni K, Gibbs, Richard A, Godwin, Andrew K, Haake, Scott, Hakimi, A Ari, Henske, Elizabeth P, Hsieh, James J, Ho, Thai H, Kanchi, Rupa S, Krishnan, Bhavani, Kwiatkowski, David J, Lui, Wembin, Merino, Maria J, Mills, Gordon B, Myers, Jerome, Nickerson, Michael L, Reuter, Victor E, Schmidt, Laura S, Shelley, C Simon, Shen, Hui, Shuch, Brian, Signoretti, Sabina, Srinivasan, Ramaprasad, Tamboli, Pheroze, Thomas, George, Vincent, Benjamin G, Vocke, Cathy D, Wheeler, David A, Yang, Lixing, Kim, William Y, Robertson, A Gordon, Spellman, Paul, Rathmell, W Kimryn, Linehan, W Marston, Caesar-Johnson, Samantha J, Demchok, John A, Felau, Ina, Kasapi, Melpomeni, Ferguson, Martin L, Hutter, Carolyn M, Sofia, Heidi J, Tarnuzzer, Roy, Wang, Zhining, Yang, Liming, Zenklusen, Jean C, Zhang, Jiashan, Chudamani, Sudha, Liu, Jia, Lolla, Laxmi, Naresh, Rashi, Pihl, Todd, Sun, Qiang, Wan, Yunhu, Wu, Ye, Cho, Juok, DeFreitas, Timothy, Frazer, Scott, Gehlenborg, Nils, Getz, Gad, Heiman, David I, Kim, Jaegil, Lawrence, Michael S, Lin, Pei, Meier, Sam, Noble, Michael S, Saksena, Gordon, Voet, Doug, Zhang, Hailei, Bernard, Brady, Chambwe, Nyasha, Dhankani, Varsha, Knijnenburg, Theo, Kramer, Roger, Leinonen, Kalle, Liu, Yuexin, Miller, Michael, Reynolds, Sheila, Shmulevich, Ilya, Thorsson, Vesteinn, Zhang, Wei, Broom, Bradley M, Hegde, Apurva M, Ju, Zhenlin, Korkut, Anil, Li, Jun, Liang, Han, and Ling, Shiyun
Subjects: Biological Sciences, Cancer Genome Atlas Research Network, Biochemistry and Cell Biology, Medical Physiology, Biological sciences
Abstract: (Cell Reports 23, 313–326; April 3, 2018) In the originally published version of this article, the author list contained two errors. Specifically, David J. Kwiatkowski was misspelled as David J. Kwaitkowski, and William Y. Kim was inadvertently written as William T. Kim. Both names have been corrected online. The authors regret this error.
Published: 2018

50. Indications of Arthroscopy in the Treatment of Patellar Instability in Children

Author: Vo, Nam Q, primary, Nguyen, Trung H, additional, and Phan, Thai H, additional
Published: 2024
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