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494 results on '"Tharian, Benjamin"'

1. Prospective, Multi-Institutional, Real-Time Next-Generation Sequencing of Pancreatic Cyst Fluid Reveals Diverse Genomic Alterations That Improve the Clinical Management of Pancreatic Cysts

Author

Paniccia, Alessandro, Polanco, Patricio M., Boone, Brian A., Wald, Abigail I., McGrath, Kevin, Brand, Randall E., Khalid, Asif, Kubiliun, Nisa, O'Broin-Lennon, Anne Marie, Park, Walter G., Klapman, Jason, Tharian, Benjamin, Inamdar, Sumant, Fasanella, Kenneth, Nasr, John, Chennat, Jennifer, Das, Rohit, DeWitt, John, Easler, Jeffrey J., Bick, Benjamin, Singh, Harkirat, Fairley, Kimberly J., Sarkaria, Savreet, Sawas, Tarek, Skef, Wasseem, Slivka, Adam, Tavakkoli, Anna, Thakkar, Shyam, Kim, Victoria, Vanderveldt, Hendrikus Dutch, Richardson, Allyson, Wallace, Michael B., Brahmbhatt, Bhaumik, Engels, Megan, Gabbert, Charles, Dugum, Mohannad, El-Dika, Samer, Bhat, Yasser, Ramrakhiani, Sanjay, Bakis, Gennadiy, Rolshud, Daniil, Millspaugh, Gordon, Tielleman, Thomas, Schmidt, Carl, Mansour, John, Marsh, Wallis, Ongchin, Melanie, Centeno, Barbara, Monaco, Sara E., Ohori, N. Paul, Lajara, Sigfred, Thompson, Elizabeth D., Hruban, Ralph H., Bell, Phoenix D., Smith, Katelyn, Permuth, Jennifer B., Vandenbussche, Christopher, Ernst, Wayne, Grupillo, Maria, Kaya, Cihan, Hogg, Melissa, He, Jin, Wolfgang, Christopher L., Lee, Kenneth K., Zeh, Herbert, Zureikat, Amer, Nikiforova, Marina N., and Singhi, Aatur D.

Published
2023
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2. Challenges of developing and executing a multi-site registry for a novel device with evolving indications for use

Author

Maranki, Jennifer L., Schwaitzberg, Steven D., Sharaiha, Reem Z., Kushnir, Vladimir M., Badurdeen, Dilhana S., Kumbhari, Vivek, Gómez, Victoria, Kumta, Nikhil A., Waye, Jerome D., Nieto, Jose, Ujiki, Michael B., Benias, Petros C., Miller, Larry S., Kedia, Prashant, Tarnasky, Paul, Mathew, Abraham, Levenick, John M., Inamdar, Sumant, Tharian, Benjamin, Nersesova, Yanina, Fredell, Lydia, Serra, Sonya, and Kochman, Michael L.

Published
2022
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3. Safety and efficacy of endoscopic submucosal dissection for rectal neoplasia: a multicenter North American experience.

Author

Yang, Dennis, Aihara, Hiroyuki, Perbtani, Yaseen B, Wang, Andrew Y, Aadam, Abdul Aziz, Tomizawa, Yutaka, Hwang, Joo Ha, Zou, Baiming, Natov, Nikola S, Siegel, Amanda, Khoshknab, Milad Pourmousavi, Khashab, Mouen A, Ngamruengphong, Saowanee, Khara, Harshit S, Diehl, David L, Maniere, Thibaut, Andrawes, Sherif, Benias, Petros, Kumta, Nikhil A, Ramay, Fariha, Kim, Raymond E, Samarasena, Jason, Chang, Kenneth, Hashimoto, Rintaro, Tharian, Benjamin, Inamdar, Sumant, Lan, Gloria, Sethi, Amrita, Nosler, Michael J, Tabash, Abdalaziz, Othman, Mohamed O, and Draganov, Peter V

Abstract

Background and aims  Rectal lesions traditionally represent the first lesions approached during endoscopic submucosal dissection (ESD) training in the West. We evaluated the safety and efficacy of rectal ESD in North America. Methods  This is a multicenter retrospective analysis of rectal ESD between January 2010 and September 2018 in 15 centers. End points included: rates of en bloc resection, R0 resection, adverse events, comparison of pre- and post-ESD histology, and factors associated with failed resection. Results  In total, 171 patients (median age 63 years; 56 % men) underwent rectal ESD (median size 43 mm). En bloc resection was achieved in 141 cases (82.5 %; 95 %CI 76.8-88.2), including 24 of 27 (88.9 %) with prior failed endoscopic mucosal resection (EMR). R0 resection rate was 74.9 % (95 %CI 68.4-81.4). Post-ESD bleeding and perforation occurred in 4 (2.3 %) and 7 (4.1 %), respectively. Covert submucosal invasive cancer (SMIC) was identified in 8.6 % of post-ESD specimens. There was one case (1/120; 0.8 %) of recurrence at a median follow-up of 31 weeks; IQR: 19-76 weeks). Older age and higher body mass index (BMI) were predictors of failed R0 resection, whereas submucosal fibrosis was associated with a higher likelihood of both failed en bloc and R0 resection. Conclusion  Rectal ESD in North America is safe and is associated with high en bloc and R0 resection rates. The presence of submucosal fibrosis was the main predictor of failed en bloc and R0 resection. ESD can be considered for select rectal lesions, and serves not only to establish a definitive tissue diagnosis but also to provide curative resection for lesions with covert advanced disease.

Published
2019

4. Safety and efficacy of a novel resection system for direct endoscopic necrosectomy of walled-off pancreas necrosis: a prospective, international, multicenter trial

Author

Stassen, Pauline M.C., de Jonge, Pieter Jan F., Bruno, Marco J., Koch, Arjun D., Trindade, Arvind J., Benias, Petros C., Sejpal, Divyesh V., Siddiqui, Uzma D., Chapman, Christopher G., Villa, Edward, Tharian, Benjamin, Inamdar, Sumant, Hwang, Joo Ha, Barakat, Monique T., Andalib, Iman, Gaidhane, Monica, Sarkar, Avik, Shahid, Haroon, Tyberg, Amy, Binmoeller, Kenneth, Watson, Rabindra R., Nett, Andrew, Schlag, Christoph, Abdelhafez, Mohamed, Friedrich-Rust, Mireen, Schlachterman, Alexander, Chiang, Austin L., Loren, David, Kowalski, Thomas, and Kahaleh, Michel

Published
2022
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19. Recent advances in endoscopic management of gastric neoplasms

Author

Tharian, Benjamin, Garcia-Saenz-de-Sicilia, Mauricio, İnamdar, Sumant, Cheema, Hira Imad, Cengiz, Cem, Tharian, Benjamin, Garcia-Saenz-de-Sicilia, Mauricio, İnamdar, Sumant, Cheema, Hira Imad, and Cengiz, Cem

Abstract

The development and clinical application of new diagnostic endoscopic technologies such as endoscopic ultrasonography with biopsy, magnification endoscopy, and narrow-band imaging, more recently supplemented by artificial intelligence, have enabled wider recognition and detection of various gastric neoplasms including early gastric cancer (EGC) and subepithelial tumors, such as gastrointestinal stromal tumors and neuroendocrine tumors. Over the last decade, the evolution of novel advanced therapeutic endoscopic techniques, such as endoscopic mucosal resection, endoscopic submucosal dissection, endoscopic full-thickness resection, and submucosal tunneling endoscopic resection, along with the advent of a broad array of endoscopic accessories, has provided a promising and yet less invasive strategy for treating gastric neoplasms with the advantage of a reduced need for gastric surgery. Thus, the management algorithms of various gastric tumors in a defined subset of the patient population at low risk of lymph node metastasis and amenable to endoscopic resection, may require revision considering upcoming data given the high success rate of en bloc resection by experienced endoscopists. Moreover, endoscopic surveillance protocols for precancerous gastric lesions will continue to be refined by systematic reviews and meta-analyses of further research. However, the lack of familiarity with subtle endoscopic changes associated with EGC, as well as longer procedural time, evolving resection techniques and tools, a steep learning curve of such high-risk procedures, and lack of coding are issues that do not appeal to many gastroenterologists in the field. This review summarizes recent advances in the endoscopic management of gastric neoplasms, with special emphasis on diagnostic and therapeutic methods and their future prospects.

Published
2023

20. Recent advances in endoscopic management of gastric neoplasms

Author

Cengiz, Cem, Cheema, Hira Imad, Tharian, Benjamin, İnamdar, Sumant, Garcia-Saenz-de-Sicilia, Mauricio, Cengiz, Cem, Cheema, Hira Imad, Tharian, Benjamin, İnamdar, Sumant, and Garcia-Saenz-de-Sicilia, Mauricio

Abstract

The development and clinical application of new diagnostic endoscopic technologies such as endoscopic ultrasonography with biopsy, magnification endoscopy, and narrow-band imaging, more recently supplemented by artificial intelligence, have enabled wider recognition and detection of various gastric neoplasms including early gastric cancer (EGC) and subepithelial tumors, such as gastrointestinal stromal tumors and neuroendocrine tumors. Over the last decade, the evolution of novel advanced therapeutic endoscopic techniques, such as endoscopic mucosal resection, endoscopic submucosal dissection, endoscopic full-thickness resection, and submucosal tunneling endoscopic resection, along with the advent of a broad array of endoscopic accessories, has provided a promising and yet less invasive strategy for treating gastric neoplasms with the advantage of a reduced need for gastric surgery. Thus, the management algorithms of various gastric tumors in a defined subset of the patient population at low risk of lymph node metastasis and amenable to endoscopic resection, may require revision considering upcoming data given the high success rate of en bloc resection by experienced endoscopists. Moreover, endoscopic surveillance protocols for precancerous gastric lesions will continue to be refined by systematic reviews and meta-analyses of further research. However, the lack of familiarity with subtle endoscopic changes associated with EGC, as well as longer procedural time, evolving resection techniques and tools, a steep learning curve of such high-risk procedures, and lack of coding are issues that do not appeal to many gastroenterologists in the field. This review summarizes recent advances in the endoscopic management of gastric neoplasms, with special emphasis on diagnostic and therapeutic methods and their future prospects.

Published
2023

23. Pancreatic Cancer Screening for At-Risk Individuals (Pancreas Scan Study): Yield, Harms, and Outcomes From a Prospective Multicenter Study

Author

Shah, Ishani, primary, Silva-Santisteban, Andy, additional, Germansky, Katharine A., additional, Trindade, Arvind, additional, Raphael, Kara L., additional, Kushnir, Vladimir, additional, Pawa, Rishi, additional, Mishra, Girish, additional, Anastasiou, Jiannis, additional, Inamdar, Sumant, additional, Tharian, Benjamin, additional, Bilal, Mohammad, additional, and Sawhney, Mandeep S., additional

Published
2023
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29. S1 Results of First Round of Enrollment from the Screening for Pancreatic Cancer in High-Risk Individuals (Pancreas Scan Study): A Prospective Multi-Center Study

Author

Shah, Ishani, primary, Silva-Santisteban, Andy, additional, Germansky, Katharine A., additional, Pawa, Rishi, additional, Kushnir, Vladimir, additional, Trindade, Arvind, additional, Anastasiou, Jiannis, additional, Raphael, Kara L., additional, Mishra, Girish, additional, Inamdar, Sumant, additional, Tharian, Benjamin, additional, and Sawhney, Mandeep S., additional

Published
2022
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39. sj-docx-1-tag-10.1177_17562848221093873 – Supplemental material for Application of artificial intelligence in diagnosis of pancreatic malignancies by endoscopic ultrasound: a systemic review

Author

Goyal, Hemant, Sherazi, Syed Ali Amir, Gupta, Shweta, Perisetti, Abhilash, Achebe, Ikechukwu, Ali, Aman, Tharian, Benjamin, Thosani, Nirav, and Sharma, Neil R.

Subjects
FOS: Clinical medicine, 111199 Nutrition and Dietetics not elsewhere classified, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, sj-docx-1-tag-10.1177_17562848221093873 for Application of artificial intelligence in diagnosis of pancreatic malignancies by endoscopic ultrasound: a systemic review by Hemant Goyal, Syed Ali Amir Sherazi, Shweta Gupta, Abhilash Perisetti, Ikechukwu Achebe, Aman Ali, Benjamin Tharian, Nirav Thosani and Neil R. Sharma in Therapeutic Advances in Gastroenterology

Published
2022
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42. TAX-Corpus: Taxonomy based Annotations for Colonoscopy Evaluation

Author

Syed, Shorabuddin, primary, Angel, Adam, additional, Syeda, Hafsa, additional, Jennings, Carole, additional, VanScoy, Joseph, additional, Syed, Mahanazuddin, additional, Greer, Melody, additional, Bhattacharyya, Sudeepa, additional, Al-Shukri, Shaymaa, additional, Zozus, Meredith, additional, Prior, Fred, additional, and Tharian, Benjamin, additional

Published
2022
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47. Scope of Artificial Intelligence in Gastrointestinal Oncology

Author

Goyal, Hemant, primary, Sherazi, Syed A. A., additional, Mann, Rupinder, additional, Gandhi, Zainab, additional, Perisetti, Abhilash, additional, Aziz, Muhammad, additional, Chandan, Saurabh, additional, Kopel, Jonathan, additional, Tharian, Benjamin, additional, Sharma, Neil, additional, and Thosani, Nirav, additional

Published
2021
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