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198 results on '"Therapondos G"'

8. Endothelin-1 contribute to maintenance of systemic but not portal haemodynamics in patients with early cirrhosis: a randomised controlled trial

Author

Tripathi, D., Therapondos, G., Ferguson, J.W., Newby, D.E., Webb, D.J., and Hayes, P.C.

Subjects
Endothelin -- Physiological aspects, Endothelin -- Research, Hemodynamics -- Physiological aspects, Hemodynamics -- Research, Liver cirrhosis -- Physiological aspects, Liver cirrhosis -- Research, Hepatic artery -- Physiological aspects, Health
Published
2006

11. The role of the transjugular intrahepatic portosystemic stent shunt (TIPSS) in the management of bleeding gastric varices: clinical and haemodynamic correlations. (Liver Disease)

Author

Tripathi, D., Therapondos, G., Jackson, E., Redhead, D.N., and Hayes, P.C.

Subjects
Care and treatment, Physiological aspects, Injuries, Stents -- Physiological aspects, Surgery -- Physiological aspects, Esophageal varices -- Injuries -- Care and treatment, Varicose veins -- Physiological aspects, Hemorrhage -- Care and treatment, Stent (Surgery) -- Physiological aspects
Abstract

Background: The transjugular intrahepatic portosystemic stent shunt (TIPSS) is effective in the management of both oesophageal and gastric variceal bleeding. Although it has been reported that gastric varices can bleed [...]

Published
2002

19. Higher early post-liver transplant mortality in recipients with severe alcoholic hepatitis versus alcoholic cirrhosis

Author

Lee, B., primary, Im, G., additional, Dodge, J., additional, Voigt, M., additional, Rice, J., additional, Lucey, M.R., additional, Foley, D., additional, Platt, L., additional, Gurakar, A., additional, Mehta, N., additional, Therapondos, G., additional, Han, H., additional, Victor, D., additional, Fix, O., additional, Dinges, L., additional, Dronamraju, D., additional, Hsu, C., additional, Rinella, M., additional, Maddur, H., additional, Eswaran, S., additional, Hause, J., additional, Ghobrial, R.M., additional, Li, Z., additional, and Terrault, N., additional

Published
2018
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20. HAEMODYNAMIC EFFECTS OF ACUTE AND CHRONIC ADMINISTRATION OF LOW DOSE CARVEDILOL, A VASODILATING BETA-BLOCKER IN PATIENTS WITH CIRRHOSIS AND PORTAL HYPERTENSION

Author

Tripathi, D., Therapondos, G., Lui, H.F., Stanley, A.J., and Hayes, P.C.

Subjects
Research, Gastrointestinal diseases -- Research
Abstract

Carvedilol is a non-selective vasodilating beta-blocker with weak alpha-1 receptor antagonism. It has 2-4 times greater beta-blocking action than propranolol. It is thought to reduce intrahepatic resistance. Aims: To assess [...]

Published
2001

21. THROMBIN IN GASTRIC VARICES

Author

Yang, W.L., Tripathi, D., Therapondos, G., and Hayes, P.C.

Subjects
Research, Gastrointestinal diseases -- Research
Abstract

Background: The management of gastric variceal haemorrhage remains a clinical challenge. We carried out a retrospective study to investigate our experience in the use of thrombin for treating gastric variceal [...]

Published
2001

24. LP17 : Novel approach for the prevention of recurrent hepatitis C in liver transplant recipients: Preliminary results from ongoing phase III trial with civacir®

Author

Terrault, N., primary, Shrestha, R., additional, Satapathy, S.K., additional, O’Leary, J.G., additional, Campsen, J., additional, Rosenau, J., additional, Spivey, J., additional, Teperman, L.W., additional, Therapondos, G., additional, Verna, E.C., additional, Vierling, J.M., additional, Schiano, T.D., additional, Sher, L., additional, Khallafi, H., additional, Victor, D., additional, Bhamidimarri, K.R., additional, Gordon, F.D., additional, Hanish, S., additional, Kulik, L.M., additional, Lake-Bakaar, G., additional, Maluf, D., additional, Porayko, M., additional, Bramer, S.L, additional, Osgood, G., additional, Chavan, S., additional, and Daelken, N., additional

Published
2015
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25. Biliary atresia and survival into adulthood without transplantation: a collaborative multicentre clinic review.

Author

Kumagi, T., Drenth, J.P.H., Guttman, O., Ng, V., Lilly, L., Therapondos, G., Hiasa, Y, Michitaka, K., Onji, M., Watanabe, Y., Sen, S., Griffiths, W., Roberts, E., Heathcote, J., Hirschfield, G.M., Kumagi, T., Drenth, J.P.H., Guttman, O., Ng, V., Lilly, L., Therapondos, G., Hiasa, Y, Michitaka, K., Onji, M., Watanabe, Y., Sen, S., Griffiths, W., Roberts, E., Heathcote, J., and Hirschfield, G.M.

Abstract

1 maart 2012, Item does not contain fulltext, BACKGROUND: Biliary atresia is a progressive biliary injury which occurs only in infants. AIMS: To review the experience of patients surviving into adulthood without the need for liver transplantation in childhood. METHODS: A multicentre review of patients with biliary atresia treated surgically who survived into adulthood without the need for transplantation. RESULTS: Twenty-two patients were identified across four centres. Median age at the last follow-up was 25 years (range: 18-46), and 21 patients had clinical features of portal hypertension. At last follow-up values of liver enzymes varied from normal to 15 x the upper limit of normal (ULN) for ALT (median 2.11 x ULN) and 9 x the ULN for ALP (median 2.02 x ULN). Six patients had a serum bilirubin > 50 mumol/l. Pruritus and jaundice were noted in 8 of 20 patients (40%) and 11 of 22 patients (50%) respectively. Thirteen patients (59.1%) were shown to have imaging features of sclerosing cholangitis, with strictures of intrahepatic bile duct(s) (IHBD), dilatation of IHBD (n = 8), or stone(s) within the IHBD (n = 5). A history of presumed bacterial cholangitis was present in 11 patients (50%). Successful pregnancies were recorded in three of fourteen female patients. Four patients underwent transplant between the ages of 20-27 years. Twenty-one patients (95.5%) were alive, including 18 (81.8%) with their native liver at the time of last follow-up. CONCLUSIONS: Some patients treated for biliary atresia will survive into adulthood with their native liver, but commonly with secondary biliary disease including cholangitis and portal hypertension.

Published
2012

30. Role of endothelin-1 in the maintenance of systemic and portal haemodynamics in patients with cirrhosis: a randomised double blind placebo controlled haemodynamic study of endothelin-A and endothelin-B receptor antagonism

Author

Tripathi, D., Therapondos, G., Ferguson, J.W., Webb, D.J., Newby, D.E., and Hayes, P.C.

Subjects
Care and treatment, Research, Health aspects, Liver diseases -- Care and treatment -- Research -- Health aspects, Endothelin -- Health aspects -- Research, Liver cirrhosis -- Care and treatment -- Research -- Health aspects
Abstract

Background: Endothelin (ET)-1 synthesis and receptor expression are increased in the injured liver. To date there are no studies to examine the role of ET-1 on systemic and portal haemodynamics [...]

Published
2004

31. The clinical course of ulcerative colitis after orthotopic liver transplantation for primary sclerosing cholangitis

Author

Seddon, A.J., Ho, G.T., Therapondos, G., Hayes, P.C., and Satsangi, J.

Subjects
Care and treatment, Research, Risk factors, Causes of, Health aspects, Ulcerative colitis -- Causes of -- Care and treatment -- Research -- Risk factors, Liver transplantation -- Health aspects -- Research, Cholangitis -- Risk factors -- Care and treatment -- Research, Liver -- Transplantation
Abstract

Background and Aims: Primary sclerosing cholangitis (PSC) is strongly associated with ulcerative colitis (UC). In patients with advanced liver disease secondary to PSC, orthotopic liver transplantation (OLT) remains the only [...]

Published
2004

50. Authors' reply.

Author

Tripathi, D., Therapondos, G., Hayes, P.C., and Redhead, D.N.

Subjects
*GASTRIC diseases, *ESOPHAGEAL varices
Abstract

Replies to comments on the article concerning the outcome of TIPS in patients with gastric varices (GV) compared to esophageal varices (OV) previously published in the periodical 'Gut.' Reason for the lower mean portosystemic pressure gradient in patients with GV bleeding relative to those with a history of OV bleeding.

Published
2003

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