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217 results on '"Thomas, Rasmi"'

1. Genetic variation that determines TAPBP expression levels associates with the course of malaria in an HLA allotype-dependent manner

Author

Walker-Sperling, Victoria, Digitale, Jean C, Viard, Mathias, Martin, Maureen P, Bashirova, Arman, Yuki, Yuko, Ramsuran, Veron, Kulkarni, Smita, Naranbhai, Vivek, Li, Hongchuan, Anderson, Stephen K, Yum, Lauren, Clifford, Robert, Kibuuka, Hannah, Ake, Julie, Thomas, Rasmi, Rowland-Jones, Sarah, Rek, John, Arinaitwe, Emmanuel, Kamya, Moses, Rodriguez-Barraquer, Isabel, Feeney, Margaret E, and Carrington, Mary

Subjects
Malaria, Biotechnology, Vector-Borne Diseases, Rare Diseases, Vaccine Related, Genetics, Immunization, Aetiology, 2.1 Biological and endogenous factors, Infection, Good Health and Well Being, Binding Sites, Genetic Variation, Histocompatibility Antigens Class I, Humans, Malaria, Falciparum, Membrane Transport Proteins, MicroRNAs, Peptides, Plasmodium falciparum, RNA, Messenger, Transcription Factor AP-2, malaria, tapasin, HLA
Abstract

HLA class I (HLA-I) allotypes vary widely in their dependence on tapasin (TAPBP), an integral component of the peptide-loading complex, to present peptides on the cell surface. We identified two single-nucleotide polymorphisms that regulate TAPBP messenger RNA (mRNA) expression in Africans, rs111686073 (G/C) and rs59097151 (A/G), located in an AP-2α transcription factor binding site and a microRNA (miR)-4486 binding site, respectively. rs111686073G and rs59097151A induced significantly higher TAPBP mRNA expression relative to the alternative alleles due to higher affinity for AP-2α and abrogation of miR-4486 binding, respectively. These variants associated with lower Plasmodium falciparum parasite prevalence and lower incidence of clinical malaria specifically among individuals carrying tapasin-dependent HLA-I allotypes, presumably by augmenting peptide loading, whereas tapasin-independent allotypes associated with relative protection, regardless of imputed TAPBP mRNA expression levels. Thus, an attenuated course of malaria may occur through enhanced breadth and/or magnitude of antigen presentation, an important consideration when evaluating vaccine efficacy.

Published
2022

2. High-resolution HLA allele and haplotype frequencies in several unrelated populations determined by next generation sequencing: 17th International HLA and Immunogenetics Workshop joint report

Author

Creary, Lisa E, Sacchi, Nicoletta, Mazzocco, Michela, Morris, Gerald P, Montero-Martin, Gonzalo, Chong, Winnie, Brown, Colin J, Dinou, Amalia, Stavropoulos-Giokas, Catherine, Gorodezky, Clara, Narayan, Saranya, Periathiruvadi, Srinivasan, Thomas, Rasmi, De Santis, Dianne, Pepperall, Jennifer, ElGhazali, Gehad E, Al Yafei, Zain, Askar, Medhat, Tyagi, Shweta, Kanga, Uma, Marino, Susana R, Planelles, Dolores, Chang, Chia-Jung, and Fernández-Viña, Marcelo A

Subjects
Genetics, 2.1 Biological and endogenous factors, Aetiology, Alleles, Disease Susceptibility, Gene Frequency, Genetic Association Studies, Genetics, Population, HLA Antigens, Haplotypes, High-Throughput Nucleotide Sequencing, Humans, Immunogenetics, Transplantation Immunology, Human leukocyte antigen, Next-generation sequencing, International HLA and Immunogenetics, Workshop, Allele frequency, Haplotype frequency, International HLA and Immunogenetics Workshop, Immunology
Abstract

The primary goal of the unrelated population HLA diversity (UPHD) component of the 17th International HLA and Immunogenetics Workshop was to characterize HLA alleles at maximum allelic-resolution in worldwide populations and re-evaluate patterns of HLA diversity across populations. The UPHD project included HLA genotype and sequence data, generated by various next-generation sequencing methods, from 4,240 individuals collated from 12 different countries. Population data included well-defined large datasets from the USA and smaller samples from Europe, Australia, and Western Asia. Allele and haplotype frequencies varied across populations from distant geographical regions. HLA genetic diversity estimated at 2- and 4-field allelic resolution revealed that diversity at the majority of loci, particularly for European-descent populations, was lower at the 2-field resolution. Several common alleles with identical protein sequences differing only by intronic substitutions were found in distinct haplotypes, revealing a more detailed characterization of linkage between variants within the HLA region. The examination of coding and non-coding nucleotide variation revealed many examples in which almost complete biunivocal relations between common alleles at different loci were observed resulting in higher linkage disequilibrium. Our reference data of HLA profiles characterized at maximum resolution from many populations is useful for anthropological studies, unrelated donor searches, transplantation, and disease association studies.

Published
2021

4. Quality control project of NGS HLA genotyping for the 17th International HLA and Immunogenetics Workshop.

Author

Osoegawa, Kazutoyo, Vayntrub, Tamara A, Wenda, Sabine, De Santis, Dianne, Barsakis, Konstantinos, Ivanova, Milena, Hsu, Susan, Barone, Jonathan, Holdsworth, Rhonda, Diviney, Mary, Askar, Medhat, Willis, Amanda, Railton, Dawn, Laflin, Sophie, Gendzekhadze, Ketevan, Oki, Arisa, Sacchi, Nicoletta, Mazzocco, Michela, Andreani, Marco, Ameen, Reem, Stavropoulos-Giokas, Catherine, Dinou, Amalia, Torres, Margareth, Dos Santos Francisco, Rodrigo, Serra-Pages, Carles, Goodridge, Damian, Balladares, Sandra, Bettinotti, Maria P, Iglehart, Brian, Kashi, Zahra, Martin, Russell, Saw, Chee Loong, Ragoussis, Jiannis, Downing, Jonathan, Navarrete, Cristina, Chong, Winnie, Saito, Katsuyuki, Petrek, Martin, Tokic, Stana, Padros, Karin, Beatriz Rodriguez, Ma, Zakharova, Viktoria, Shragina, Olga, Marino, Susana R, Brown, Nicholas K, Shiina, Takashi, Suzuki, Shingo, Spierings, Eric, Zhang, Qiuheng, Yin, Yuxin, Morris, Gerald P, Hernandez, Ana, Ruiz, Phillip, Khor, Seik-Soon, Tokunaga, Katsushi, Geretz, Aviva, Thomas, Rasmi, Yamamoto, Fumiko, Mallempati, Kalyan C, Gangavarapu, Sridevi, Kanga, Uma, Tyagi, Shweta, Marsh, Steven GE, Bultitude, Will P, Liu, Xiangjun, Cao, Dajiang, Penning, Maarten, Hurley, Carolyn K, Cesbron, Anne, Mueller, Claudia, Mytilineos, Joannis, Weimer, Eric T, Bengtsson, Mats, Fischer, Gottfried, Hansen, John A, Chang, Chia-Jung, Mack, Steven J, Creary, Lisa E, and Fernandez-Viña, Marcelo A

Subjects
Humans, HLA Antigens, Histocompatibility Testing, Pilot Projects, Immunogenetics, Genotype, Alleles, International Cooperation, Quality Control, Software, Consensus Development Conferences as Topic, High-Throughput Nucleotide Sequencing, NGS HLA typing, Proficiency testing, Quality control, Reference cell panel, Genetics, Immunology
Abstract

The 17th International HLA and Immunogenetics Workshop (IHIW) organizers conducted a Pilot Study (PS) in which 13 laboratories (15 groups) participated to assess the performance of the various sequencing library preparation protocols, NGS platforms and software in use prior to the workshop. The organizers sent 50 cell lines to each of the 15 groups, scored the 15 independently generated sets of NGS HLA genotyping data, and generated "consensus" HLA genotypes for each of the 50 cell lines. Proficiency Testing (PT) was subsequently organized using four sets of 24 cell lines, selected from 48 of 50 PS cell lines, to validate the quality of NGS HLA typing data from the 34 participating IHIW laboratories. Completion of the PT program with a minimum score of 95% concordance at the HLA-A, HLA-B, HLA-C, HLA-DRB1 and HLA-DQB1 loci satisfied the requirements to submit NGS HLA typing data for the 17th IHIW projects. Together, these PS and PT efforts constituted the 17th IHIW Quality Control project. Overall PT concordance rates for HLA-A, HLA-B, HLA-C, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQB1, HLA-DRB1, HLA-DRB3, HLA-DRB4 and HLA-DRB5 were 98.1%, 97.0% and 98.1%, 99.0%, 98.6%, 98.8%, 97.6%, 96.0%, 99.1%, 90.0% and 91.7%, respectively. Across all loci, the majority of the discordance was due to allele dropout. The high cost of NGS HLA genotyping per experiment likely prevented the retyping of initially failed HLA loci. Despite the high HLA genotype concordance rates of the software, there remains room for improvement in the assembly of more accurate consensus DNA sequences by NGS HLA genotyping software.

Published
2019

5. Acute HIV-1 infection viremia associate with rebound upon treatment interruption

Author

Mdluli, Thembi, Li, Yifan, Pinyakorn, Suteeraporn, Reeves, Daniel B., Cardozo-Ojeda, E. Fabian, Yates, Adam, Intasan, Jintana, Tipsuk, Somporn, Phanuphak, Nittaya, Sacdalan, Carlo, Colby, Donn J., Kroon, Eugène, Crowell, Trevor A., Thomas, Rasmi, Robb, Merlin L., Ananworanich, Jintanat, de Souza, Mark, Phanuphak, Praphan, Stieh, Daniel J., Tomaka, Frank L., Trautmann, Lydie, Ake, Julie A., Hsu, Denise C., Francisco, Leilani V., Vasan, Sandhya, and Rolland, Morgane

Published
2022
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6. Associations of human leukocyte antigen with neutralizing antibody titers in a tetravalent dengue vaccine phase 2 efficacy trial in Thailand

Author

Thomas, Rasmi, Chansinghakul, Danaya, Limkittikul, Kriengsak, Gilbert, Peter B., Hattasingh, Weerawan, Moodie, Zoe, Shangguan, Shida, Frago, Carina, Dulyachai, Wut, Li, Shuying Sue, Jarman, Richard G., Geretz, Aviva, Bouckenooghe, Alain, Sabchareon, Arunee, Juraska, Michal, Ehrenberg, Philip, Michael, Nelson L., Bailleux, Fabrice, Bryant, Chris, and Gurunathan, Sanjay

Published
2022
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7. HLA-C downregulation by HIV-1 adapts to host HLA genotype.

Author

Bachtel, Nathaniel D, Umviligihozo, Gisele, Pickering, Suzanne, Mota, Talia M, Liang, Hua, Del Prete, Gregory Q, Chatterjee, Pramita, Lee, Guinevere Q, Thomas, Rasmi, Brockman, Mark A, Neil, Stuart, Carrington, Mary, Bwana, Bosco, Bangsberg, David R, Martin, Jeffrey N, Kallas, Esper G, Donini, Camila S, Cerqueira, Natalia B, O'Doherty, Una T, Hahn, Beatrice H, Jones, R Brad, Brumme, Zabrina L, Nixon, Douglas F, and Apps, Richard

Subjects
Humans, HIV-1, HIV Infections, HLA-C Antigens, Disease Reservoirs, Down-Regulation, Amino Acid Sequence, Genotype, Human Immunodeficiency Virus Proteins, Viral Regulatory and Accessory Proteins, Host-Pathogen Interactions, Genetic Variation, Immune Evasion, Microbiology, Immunology, Medical Microbiology, Virology
Abstract

HIV-1 can downregulate HLA-C on infected cells, using the viral protein Vpu, and the magnitude of this downregulation varies widely between primary HIV-1 variants. The selection pressures that result in viral downregulation of HLA-C in some individuals, but preservation of surface HLA-C in others are not clear. To better understand viral immune evasion targeting HLA-C, we have characterized HLA-C downregulation by a range of primary HIV-1 viruses. 128 replication competent viral isolates from 19 individuals with effective anti-retroviral therapy, show that a substantial minority of individuals harbor latent reservoir virus which strongly downregulates HLA-C. Untreated infections display no change in HLA-C downregulation during the first 6 months of infection, but variation between viral quasispecies can be detected in chronic infection. Vpu molecules cloned from plasma of 195 treatment naïve individuals in chronic infection demonstrate that downregulation of HLA-C adapts to host HLA genotype. HLA-C alleles differ in the pressure they exert for downregulation, and individuals with higher levels of HLA-C expression favor greater viral downregulation of HLA-C. Studies of primary and mutant molecules identify 5 residues in the transmembrane region of Vpu, and 4 residues in the transmembrane domain of HLA-C, which determine interactions between Vpu and HLA. The observed adaptation of Vpu-mediated downregulation to host genotype indicates that HLA-C alleles differ in likelihood of mediating a CTL response that is subverted by viral downregulation, and that preservation of HLA-C expression is favored in the absence of these responses. Finding that latent reservoir viruses can downregulate HLA-C could have implications for HIV-1 cure therapy approaches in some individuals.

Published
2018

8. Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1

Author

Martin, Maureen P, Naranbhai, Vivek, Shea, Patrick R, Qi, Ying, Ramsuran, Veron, Vince, Nicolas, Gao, Xiaojiang, Thomas, Rasmi, Brumme, Zabrina L, Carlson, Jonathan M, Wolinsky, Steven M, Goedert, James J, Walker, Bruce D, Segal, Florencia P, Deeks, Steven G, Haas, David W, Migueles, Stephen A, Connors, Mark, Michael, Nelson, Fellay, Jacques, Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A, Lafont, Bernard A, Pymm, Phillip, Saunders, Philippa M, Widjaja, Jacqueline, Wong, Shu Cheng, Vivian, Julian P, Rossjohn, Jamie, Brooks, Andrew G, and Carrington, Mary

Subjects
Medical Microbiology, Biomedical and Clinical Sciences, Immunology, Infectious Diseases, Genetics, HIV/AIDS, Human Genome, Clinical Research, Sexually Transmitted Infections, 2.1 Biological and endogenous factors, Aetiology, Infection, Good Health and Well Being, Adult, Cohort Studies, Female, Genetic Variation, HIV Infections, HIV-1, HLA-B Antigens, Humans, Male, Middle Aged, Receptors, KIR3DL1, AIDS/HIV, Innate immunity, MHC class 1, NK cells, Medical and Health Sciences, Biological sciences, Biomedical and clinical sciences, Health sciences
Abstract

HLA-B*57 control of HIV involves enhanced CD8+ T cell responses against infected cells, but extensive heterogeneity exists in the level of HIV control among B*57+ individuals. Using whole-genome sequencing of untreated B*57+ HIV-1-infected controllers and noncontrollers, we identified a single variant (rs643347A/G) encoding an isoleucine-to-valine substitution at position 47 (I47V) of the inhibitory killer cell immunoglobulin-like receptor KIR3DL1 as the only significant modifier of B*57 protection. The association was replicated in an independent cohort and across multiple outcomes. The modifying effect of I47V was confined to B*57:01 and was not observed for the closely related B*57:03. Positions 2, 47, and 54 tracked one another nearly perfectly, and 2 KIR3DL1 allotypes differing only at these 3 positions showed significant differences in binding B*57:01 tetramers, whereas the protective allotype showed lower binding. Thus, variation in an immune NK cell receptor that binds B*57:01 modifies its protection. These data highlight the exquisite specificity of KIR-HLA interactions in human health and disease.

Published
2018

10. Multivariate analysis of FcR-mediated NK cell functions identifies unique clustering among humans and rhesus macaques

Author

Tuyishime, Marina, primary, Spreng, Rachel L., additional, Hueber, Brady, additional, Nohara, Junsuke, additional, Goodman, Derrick, additional, Chan, Cliburn, additional, Barfield, Richard, additional, Beck, Whitney E., additional, Jha, Shalini, additional, Asdell, Stephanie, additional, Wiehe, Kevin, additional, He, Max M., additional, Easterhoff, David, additional, Conley, Haleigh E., additional, Hoxie, Taylor, additional, Gurley, Thaddeus, additional, Jones, Caroline, additional, Adhikary, Nihar Deb, additional, Villinger, Francois, additional, Thomas, Rasmi, additional, Denny, Thomas N., additional, Moody, Michael Anthony, additional, Tomaras, Georgia D., additional, Pollara, Justin, additional, Reeves, R. Keith, additional, and Ferrari, Guido, additional

Published
2023
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11. Safety and immunogenicity of Ad26 and MVA vaccines in acutely treated HIV and effect on viral rebound after antiretroviral therapy interruption

Author

Colby, Donn J., Sarnecki, Michal, Barouch, Dan H., Tipsuk, Somporn, Stieh, Daniel J., Kroon, Eugène, Schuetz, Alexandra, Intasan, Jintana, Sacdalan, Carlo, Pinyakorn, Suteeraporn, Grandin, Pornsuk, Song, Hongshuo, Tovanabutra, Sodsai, Shubin, Zhanna, Kim, Dohoon, Paquin-Proulx, Dominic, Eller, Michael A., Thomas, Rasmi, de Souza, Mark, Wieczorek, Lindsay, Polonis, Victoria R., Pagliuzza, Amélie, Chomont, Nicolas, Peter, Lauren, Nkolola, Joseph P., Vingerhoets, Johan, Truyers, Carla, Pau, Maria G., Schuitemaker, Hanneke, Phanuphak, Nittaya, Michael, Nelson, Robb, Merlin L., Tomaka, Frank L., and Ananworanich, Jintanat

Published
2020
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12. Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor

Author

Dussupt, Vincent, Sankhala, Rajeshwer S., Gromowski, Gregory D., Donofrio, Gina, De La Barrera, Rafael A., Larocca, Rafael A., Zaky, Weam, Mendez-Rivera, Letzibeth, Choe, Misook, Davidson, Edgar, McCracken, Michael K., Brien, James D., Abbink, Peter, Bai, Hongjun, Bryan, Aubrey L., Bias, Candace Hope, Berry, Irina Maljkovic, Botero, Nubia, Cook, Tanya, Doria-Rose, Nicole A., Escuer, Ariadna Grinyo i, Frimpong, Justice Akuoku, Geretz, Aviva, Hernandez, Mayda, Hollidge, Bradley S., Jian, Ningbo, Kabra, Kareem, Leggat, David J., Liu, Jinyan, Pinto, Amelia K., Rutvisuttinunt, Wiriya, Setliff, Ian, Tran, Ursula, Townsley, Samantha, Doranz, Benjamin J., Rolland, Morgane, McDermott, Adrian B., Georgiev, Ivelin S., Thomas, Rasmi, Robb, Merlin L., Eckels, Kenneth H., Barranco, Elizabeth, Koren, Michael, Smith, Darci R., Jarman, Richard G., George, Sarah L., Stephenson, Kathryn E., Barouch, Dan H., Modjarrad, Kayvon, Michael, Nelson L., Joyce, M. Gordon, and Krebs, Shelly J.

Published
2020
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13. Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial

Author

Ake, Julie A., Akapirat, Siriwat, Bose, Meera, Cale, Evan, Chan, Phillip, Chanthaburanun, Sararut, Churikanont, Nampueng, Dawson, Peter, Dumrongpisutikul, Netsiri, Getchalarat, Saowanit, Jongrakthaitae, Surat, Jongsakul, Krisada, Lerdlum, Sukalaya, Manasnayakorn, Sopark, McCullough, Corinne, Milazzo, Mark, Nuntapinit, Bessara, On, Kier, Ouellette, Madelaine, Phanuphak, Praphan, Sanders-Buell, Eric, Sangnoi, Nongluck, Shangguan, Shida, Sirivichayakul, Sunee, Tragonlugsana, Nipattra, Trichavaroj, Rapee, Ubolyam, Sasiwimol, Vasan, Sandhya, Wattanaboonyongcharoen, Phandee, Yamchuenpong, Thipvadee, Crowell, Trevor A, Colby, Donn J, Pinyakorn, Suteeraporn, Sacdalan, Carlo, Pagliuzza, Amélie, Intasan, Jintana, Benjapornpong, Khunthalee, Tangnaree, Kamonkan, Chomchey, Nitiya, Kroon, Eugène, de Souza, Mark S, Tovanabutra, Sodsai, Rolland, Morgane, Eller, Michael A, Paquin-Proulx, Dominic, Bolton, Diane L, Tokarev, Andrey, Thomas, Rasmi, Takata, Hiroshi, Trautmann, Lydie, Krebs, Shelly J, Modjarrad, Kayvon, McDermott, Adrian B, Bailer, Robert T, Doria-Rose, Nicole, Patel, Bijal, Gorelick, Robert J, Fullmer, Brandie A, Schuetz, Alexandra, Grandin, Pornsuk V, O'Connell, Robert J, Ledgerwood, Julie E, Graham, Barney S, Tressler, Randall, Mascola, John R, Chomont, Nicolas, Michael, Nelson L, Robb, Merlin L, Phanuphak, Nittaya, and Ananworanich, Jintanat

Published
2019
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15. Transmission of highly virulent CXCR4 tropic HIV-1 through the mucosal route in an individual with a wild-type CCR5 genotype

Author

Song, Hongshuo, primary, Marichannegowda, Manukumar, additional, Setua, Saini, additional, Bose, Meera, additional, Sanders-Buell, Eric, additional, King, David, additional, Zemil, Michelle, additional, Wieczorek, Lindsay, additional, Diaz-Mendez, Felisa, additional, Chomont, Nicolas, additional, Thomas, Rasmi, additional, Francisco, Leilani, additional, Eller, Leigh Anne, additional, Polonis, Victoria, additional, Tovanabutra, Sodsai, additional, Tagaya, Yutaka, additional, Michael, Nelson, additional, and Robb, Merlin, additional

Published
2023
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16. Transmission of highly virulent CXCR4 tropic HIV-1 through the mucosal route in an individual with a wild-type CCR5 genotype

Author

Marichannegowda, Manukumar Honnayakanahalli, primary, Setua, Saini, additional, Bose, Meera, additional, Sanders-Buell, Eric, additional, King, David, additional, Zemil, Michelle, additional, Wieczorek, Lindsay, additional, Diaz-Mendez, Felisa, additional, Chomont, Nicolas, additional, Thomas, Rasmi, additional, Francisco, Leilani, additional, Eller, Leigh Anne, additional, Polonis, Victoria R., additional, Tovanabutra, Sodsai, additional, Tagaya, Yutaka, additional, Michael, Nelson L., additional, Robb, Merlin L., additional, and Song, Hongshuo, additional

Published
2023
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17. Distinct mucosal and systemic immunological characteristics in transgender women potentially relating to HIV acquisition

Author

Schuetz, Alexandra, primary, Corley, Michael J., additional, Sacdalan, Carlo, additional, Phuang-Ngern, Yuwadee, additional, Nakpor, Thitiyanun, additional, Wansom, Tanyaporn, additional, Ehrenberg, Philip K., additional, Sriplienchan, Somchai, additional, Thomas, Rasmi, additional, Ratnaratorn, Nisakorn, additional, Sukhumvittaya, Suchada, additional, Tragonlugsana, Nipattra, additional, Slike, Bonnie M., additional, Akapirat, Siriwat, additional, Pinyakorn, Suteeraporn, additional, Rerknimitr, Rungsun, additional, Pang, Alina P.S., additional, Kroon, Eugène, additional, Teeratakulpisan, Nipat, additional, Krebs, Shelly J., additional, Phanuphak, Nittaya, additional, Ndhlovu, Lishomwa C., additional, and Vasan, Sandhya, additional

Published
2023
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18. Single-cell transcriptomics identifies prothymosin α restriction of HIV-1 in vivo

Author

Geretz, Aviva, primary, Ehrenberg, Philip K., additional, Clifford, Robert J., additional, Laliberté, Alexandre, additional, Prelli Bozzo, Caterina, additional, Eiser, Daina, additional, Kundu, Gautam, additional, Yum, Lauren K., additional, Apps, Richard, additional, Creegan, Matthew, additional, Gunady, Mohamed, additional, Shangguan, Shida, additional, Sanders-Buell, Eric, additional, Sacdalan, Carlo, additional, Phanuphak, Nittaya, additional, Tovanabutra, Sodsai, additional, Russell, Ronnie M., additional, Bibollet-Ruche, Frederic, additional, Robb, Merlin L., additional, Michael, Nelson L., additional, Ake, Julie A., additional, Vasan, Sandhya, additional, Hsu, Denise C., additional, Hahn, Beatrice H., additional, Kirchhoff, Frank, additional, and Thomas, Rasmi, additional

Published
2023
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19. Influence of HLA-C Expression Level on HIV Control

Author

Apps, Richard, Qi, Ying, Carlson, Jonathan M, Chen, Haoyan, Gao, Xiaojiang, Thomas, Rasmi, Yuki, Yuko, Del Prete, Greg Q, Goulder, Philip, Brumme, Zabrina L, Brumme, Chanson J, John, Mina, Mallal, Simon, Nelson, George, Bosch, Ronald, Heckerman, David, Stein, Judy L, Soderberg, Kelly A, Moody, M Anthony, Denny, Thomas N, Zeng, Xue, Fang, Jingyuan, Moffett, Ashley, Lifson, Jeffrey D, Goedert, James J, Buchbinder, Susan, Kirk, Gregory D, Fellay, Jacques, McLaren, Paul, Deeks, Steven G, Pereyra, Florencia, Walker, Bruce, Michael, Nelson L, Weintrob, Amy, Wolinsky, Steven, Liao, Wilson, and Carrington, Mary

Subjects
Medical Microbiology, Biomedical and Clinical Sciences, Immunology, Genetics, Sexually Transmitted Infections, Infectious Diseases, Clinical Research, HIV/AIDS, Cancer, 2.1 Biological and endogenous factors, Aetiology, Infection, Inflammatory and immune system, Black or African American, Alleles, Amino Acid Sequence, Anti-Retroviral Agents, Crohn Disease, Gene Expression Regulation, HIV, HIV Infections, HLA-C Antigens, Humans, Immunodominant Epitopes, Molecular Sequence Data, Mutation, Peptide Fragments, Polymorphism, Single Nucleotide, T-Lymphocytes, Cytotoxic, Viral Load, General Science & Technology
Abstract

A variant upstream of human leukocyte antigen C (HLA-C) shows the most significant genome-wide effect on HIV control in European Americans and is also associated with the level of HLA-C expression. We characterized the differential cell surface expression levels of all common HLA-C allotypes and tested directly for effects of HLA-C expression on outcomes of HIV infection in 5243 individuals. Increasing HLA-C expression was associated with protection against multiple outcomes independently of individual HLA allelic effects in both African and European Americans, regardless of their distinct HLA-C frequencies and linkage relationships with HLA-B and HLA-A. Higher HLA-C expression was correlated with increased likelihood of cytotoxic T lymphocyte responses and frequency of viral escape mutation. In contrast, high HLA-C expression had a deleterious effect in Crohn's disease, suggesting a broader influence of HLA expression levels in human disease.

Published
2013

20. HLA-B*57 and B*58 Associate with Predictors of Reservoir Size in an Acutely Treated HIV Cohort

Author

Shangguan, Shida, primary, Ehrenberg, Philip K., additional, Geretz, Aviva, additional, Butler, Lauryn, additional, Pinyakorn, Suteeraporn, additional, Sriplienchan, Somchai, additional, Sacdalan, Carlo, additional, Chomchey, Nitiya, additional, Phanuphak, Nittaya, additional, Tovanabutra, Sodsai, additional, Vasan, Sandhya, additional, Hsu, Denise, additional, and Thomas, Rasmi, additional

Published
2023
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22. Integrated systems approach defines the antiviral pathways conferring protection by the RV144 HIV vaccine

Author

Fourati, Slim, Ribeiro, Susan Pereira, Blasco Tavares Pereira Lopes, Filipa, Talla, Aarthi, Lefebvre, Francois, Cameron, Mark, Kaewkungwal, J., Pitisuttithum, P., Nitayaphan, S., Rerks-Ngarm, S., Kim, Jerome H., Thomas, Rasmi, Gilbert, Peter B., Tomaras, Georgia D., Koup, Richard A., Michael, Nelson L., McElrath, M. Juliana, Gottardo, Raphael, and Sékaly, Rafick-Pierre

Published
2019
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23. Fc receptor engagement of HIV-1 Env-specific antibodies in mothers and infants predicts reduced vertical transmission

Author

Barrows, Brittani M., primary, Krebs, Shelly J., additional, Jian, Ningbo, additional, Zemil, Michelle, additional, Slike, Bonnie M., additional, Dussupt, Vincent, additional, Tran, Ursula, additional, Mendez-Rivera, Letzibeth, additional, Chang, David, additional, O’Sullivan, Anne Marie, additional, Mann, Brendan, additional, Sanders-Buell, Eric, additional, Shubin, Zhanna, additional, Creegan, Matt, additional, Paquin-Proulx, Dominic, additional, Ehrenberg, Philip, additional, Laurence-Chenine, Agnes, additional, Srithanaviboonchai, Kriengkrai, additional, Thomas, Rasmi, additional, Eller, Michael A., additional, Ferrari, Guido, additional, Robb, Merlin, additional, Rao, Venigalla, additional, Tovanabutra, Sodsai, additional, Polonis, Victoria R., additional, and Wieczorek, Lindsay, additional

Published
2022
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24. Long-term antiretroviral therapy initiated in acute HIV infection prevents residual dysfunction of HIV-specific CD8+ T cells

Author

Takata, Hiroshi, primary, Kakazu, Juyeon C., additional, Mitchell, Julie L., additional, Kroon, Eugene, additional, Colby, Donn J., additional, Sacdalan, Carlo, additional, Bai, Hongjun, additional, Ehrenberg, Philip K., additional, Geretz, Aviva, additional, Buranapraditkun, Supranee, additional, Pinyakorn, Suteeraporn, additional, Intasan, Jintana, additional, Tipsuk, Somporn, additional, Suttichom, Duanghathai, additional, Prueksakaew, Peeriya, additional, Chalermchai, Thep, additional, Chomchey, Nitiya, additional, Phanuphak, Nittaya, additional, de Souza, Mark, additional, Michael, Nelson L., additional, Robb, Merlin L., additional, Haddad, Elias K., additional, Crowell, Trevor A, additional, Vasan, Sandhya, additional, Valcour, Victor G., additional, Douek, Daniel C., additional, Thomas, Rasmi, additional, Rolland, Morgane, additional, Chomont, Nicolas, additional, Ananworanich, Jintanat, additional, Trautmann, Lydie, additional, Teeratakulpisarn, Nipat, additional, Pattanachaiwit, Supanit, additional, Sriplienchan, Somchai, additional, Tantivitayakul, Ponpen, additional, Kanaprach, Ratchapong, additional, Ruxrungtham, Kiat, additional, Dumrongpisutikul, Netsiri, additional, Rojnuckarin, Ponlapat, additional, Chottanapund, Suthat, additional, Poltavee, Kultida, additional, Luekasemsuk, Tassanee, additional, Savadsuk, Hathairat, additional, Puttamsawin, Suwanna, additional, Benjapornpong, Khunthalee, additional, Ratnaratorn, Nisakorn, additional, Tangnaree, Kamonkan, additional, Munkong, Chutharat, additional, Thaimanee, Rommanus, additional, Eamyoung, Patcharin, additional, Ubolyam, Sasiwimol, additional, Lerdlum, Sukalya, additional, Manasnayakorn, Sopark, additional, Rerknimitr, Rugsun, additional, Sirivichayakul, Sunee, additional, Wattanaboonyongcharoen, Phandee, additional, Cowden, Jessica, additional, Schuetz, Alexandra, additional, Akapirat, Siriwat, additional, Churikanont, Nampueng, additional, Getchalarat, Saowanit, additional, Hsu, Denise, additional, Turk, Ellen, additional, Butterworth, Oratai, additional, Milazzo, Mark, additional, Eller, Leigh Anne, additional, Ake, Julie, additional, Spudich, Serena, additional, Fox, CAPT Lawrence, additional, Ratto-Kim, Silvia, additional, DeGruttola, Victor, additional, Chinvarun, Yotin, additional, Sithinamsuwan, Pasiri, additional, Fletcher, James, additional, and Shiramizu, Bruce, additional

Published
2022
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25. HLA-B∗46 associates with rapid HIV disease progression in Asian cohorts and prominent differences in NK cell phenotype

Author

Li, Shuying S., primary, Hickey, Andrew, additional, Shangguan, Shida, additional, Ehrenberg, Philip K., additional, Geretz, Aviva, additional, Butler, Lauryn, additional, Kundu, Gautam, additional, Apps, Richard, additional, Creegan, Matthew, additional, Clifford, Robert J., additional, Pinyakorn, Suteeraporn, additional, Eller, Leigh Anne, additional, Luechai, Pikunchai, additional, Gilbert, Peter B., additional, Holtz, Timothy H., additional, Chitwarakorn, Anupong, additional, Sacdalan, Carlo, additional, Kroon, Eugène, additional, Phanuphak, Nittaya, additional, de Souza, Mark, additional, Ananworanich, Jintanat, additional, O'Connell, Robert J., additional, Robb, Merlin L., additional, Michael, Nelson L., additional, Vasan, Sandhya, additional, and Thomas, Rasmi, additional

Published
2022
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26. Genetic variation that determinesTAPBPexpression levels associates with the course of malaria in an HLA allotype-dependent manner

Author

Walker-Sperling, Victoria, primary, Digitale, Jean C., additional, Viard, Mathias, additional, Martin, Maureen P., additional, Bashirova, Arman, additional, Yuki, Yuko, additional, Ramsuran, Veron, additional, Kulkarni, Smita, additional, Naranbhai, Vivek, additional, Li, Hongchuan, additional, Anderson, Stephen K., additional, Yum, Lauren, additional, Clifford, Robert, additional, Kibuuka, Hannah, additional, Ake, Julie, additional, Thomas, Rasmi, additional, Rowland-Jones, Sarah, additional, Rek, John, additional, Arinaitwe, Emmanuel, additional, Kamya, Moses, additional, Rodriguez-Barraquer, Isabel, additional, Feeney, Margaret E., additional, and Carrington, Mary, additional

Published
2022
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27. HIV-1 infections with multiple founders are associated with higher viral loads than infections with single founders

Author

Janes, Holly, Herbeck, Joshua T., Tovanabutra, Sodsai, Thomas, Rasmi, Frahm, Nicole, Duerr, Ann, Hural, John, Corey, Lawrence, Self, Steve G., Buchbinder, Susan P., McElrath, M. Juliana, O'Connell, Robert J., Paris, Robert M., Rerks-Ngarm, Supachai, Nitayaphan, Sorachai, Pitisuttihum, Punnee, Kaewkungwal, Jaranit, Robb, Merlin L., Michael, Nelson L., Mullins, James I., Kim, Jerome H., Gilbert, Peter B., and Rolland, Morgane

Subjects
Genetic variation -- Research, HIV infection -- Development and progression -- Diagnosis -- Research, Biological sciences, Health
Abstract

Given the variation in the HIV-1 viral load (VL) set point across subjects, as opposed to a fairly stable VL over time within an infected individual, it is important to identify the characteristics of the host and virus that affect VL set point. Although recently infected individuals with multiple phylogenetically linked HIV-1 founder variants represent a minority of HIV-1 infections, we found--in two different cohorts--that more diverse HIV-1 populations in early infection were associated with significantly higher VL 1 year after HIV-1 diagnosis., Approximately 20-35% of individuals become infected with multiple founder HIV-1 variants (1-3). We therefore sought to evaluate whether genetic characteristics of the founder viral populations could influence markers of clinical [...]

Published
2015
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28. FCGR2C polymorphisms associate with hiv-1 vaccine protection in rv144 trial

Author

Li, Shuying S., Gilbert, Peter B., Tomaras, Georgia D., Kijak, Gustavo, Ferrari, Guido, Thomas, Rasmi, Pyo, Chul-Woo, Zolla-Pazner, Susan, Montefiori, David, Liao, Hua-Xin, Nabel, Gary, Pinter, Abraham, Evans, David T., Gottardo, Raphael, Dai, James Y., Janes, Holly, Morris, Daryl, Fong, Youyi, Edlefsen, Paul T., Li, Fusheng, Frahm, Nicole, Alpert, Michael D., Prentice, Heather, Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Kaewkungwal, Jaranit, Nitayaphan, Sorachai, Robb, Merlin L., O'Connell, Robert J., Haynes, Barton F., Michael, Nelson L., Kim, Jerome H., McElrath, M. Juliana, and Geraghty, Daniel E.

Subjects
Immunoglobulins -- Research -- Health aspects, Genetic polymorphisms -- Research, Clinical trials -- Analysis, Fc receptors -- Research, HIV infection -- Genetic aspects -- Research -- Risk factors -- Patient outcomes -- Development and progression, Health care industry
Abstract

The phase III RV144 HIV-1 vaccine trial estimated vaccine efficacy (VE) to be 31.2%. This trial demonstrated that the presence of HIV-1-specific IgG-binding Abs to envelope (Env) V1V2 inversely correlated with infection risk, while the presence of Env-specific plasma IgA Abs directly correlated with risk of HIV-1 infection. Moreover, Ab-dependent cellular cytotoxicity responses inversely correlated with risk of infection in vaccine recipients with low IgA; therefore, we hypothesized that vaccine-induced Fc receptor-mediated (FcR-mediated) Ab function is indicative of vaccine protection. We sequenced exons and surrounding areas of FcR-encoding genes and found one FCGR2C tag SNP (rs114945036) that associated with VE against HIV-1 subtype CRF01_AE, with lysine at position 169 (169K) in the V2 loop (CRF01_AE 169K). Individuals carrying CC in this SNP had an estimated VE of 15%, while individuals carrying CT or TT exhibited a VE of 91%. Furthermore, the rs114945036 SNP was highly associated with 3 other FCGR2CSNPs (rs138747765, rs78603008, and rs373013207). Env-specific IgG and IgG3 Abs, IgG avidity, and neutralizing Abs inversely correlated with CRF01_AE 169K HIV-1 infection risk in the CT- or TT carrying vaccine recipients only. These data suggest a potent role of Fc-γ receptors and Fc-mediated Ab function in conferring protection from transmission risk in the RV144 VE trial., Introduction The Thai phase III RV144 vaccine trial, which tested the ALVACHIV (vCP1521) prime and bivalent clade B/E recombinant gp120 boost vaccine regimen, showed an estimated vaccine efficacy (VE) of [...]

Published
2014
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30. Monocyte-derived transcriptome signature indicates antibody-dependent cellular phagocytosis as a potential mechanism of vaccine-induced protection against HIV-1

Author

Shangguan, Shida, primary, Ehrenberg, Philip K, additional, Geretz, Aviva, additional, Yum, Lauren, additional, Kundu, Gautam, additional, May, Kelly, additional, Fourati, Slim, additional, Nganou-Makamdop, Krystelle, additional, Williams, LaTonya D, additional, Sawant, Sheetal, additional, Lewitus, Eric, additional, Pitisuttithum, Punnee, additional, Nitayaphan, Sorachai, additional, Chariyalertsak, Suwat, additional, Rerks-Ngarm, Supachai, additional, Rolland, Morgane, additional, Douek, Daniel C, additional, Gilbert, Peter, additional, Tomaras, Georgia D, additional, Michael, Nelson L, additional, Vasan, Sandhya, additional, and Thomas, Rasmi, additional

Published
2021
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31. Author response: Monocyte-derived transcriptome signature indicates antibody-dependent cellular phagocytosis as a potential mechanism of vaccine-induced protection against HIV-1

Author

Shangguan, Shida, primary, Ehrenberg, Philip K, additional, Geretz, Aviva, additional, Yum, Lauren, additional, Kundu, Gautam, additional, May, Kelly, additional, Fourati, Slim, additional, Nganou-Makamdop, Krystelle, additional, Williams, LaTonya D, additional, Sawant, Sheetal, additional, Lewitus, Eric, additional, Pitisuttithum, Punnee, additional, Nitayaphan, Sorachai, additional, Chariyalertsak, Suwat, additional, Rerks-Ngarm, Supachai, additional, Rolland, Morgane, additional, Douek, Daniel C, additional, Gilbert, Peter, additional, Tomaras, Georgia D, additional, Michael, Nelson L, additional, Vasan, Sandhya, additional, and Thomas, Rasmi, additional

Published
2021
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32. Monocyte-derived transcriptome signature indicates antibody-dependent cellular phagocytosis as the primary mechanism of vaccine-induced protection against HIV-1

Author

Shangguan, Shida, primary, Ehrenberg, Philip K., additional, Geretz, Aviva, additional, Yum, Lauren, additional, Kundu, Gautam, additional, May, Kelly, additional, Fourati, Slim, additional, Nganou-Makamdop, Krystelle, additional, Williams, LaTonya D., additional, Sawant, Sheetal, additional, Lewitus, Eric, additional, Pitisuttithum, Punnee, additional, Nitayaphan, Sorachai, additional, Chariyalertsak, Suwat, additional, Rerks-Ngarm, Supachai, additional, Rolland, Morgane, additional, Douek, Daniel, additional, Gilbert, Peter, additional, Tomaras, Georgia D., additional, Michael, Nelson, additional, Vasan, Sandhya, additional, and Thomas, Rasmi, additional

Published
2021
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33. B cell engagement with HIV-1 founder virus envelope predicts development of broadly neutralizing antibodies

Author

Townsley, Samantha M., primary, Donofrio, Gina C., additional, Jian, Ningbo, additional, Leggat, David J., additional, Dussupt, Vincent, additional, Mendez-Rivera, Letzibeth, additional, Eller, Leigh Anne, additional, Cofer, Lauryn, additional, Choe, Misook, additional, Ehrenberg, Philip K., additional, Geretz, Aviva, additional, Gift, Syna, additional, Grande, Rebecca, additional, Lee, Anna, additional, Peterson, Caroline, additional, Piechowiak, Mary Bryson, additional, Slike, Bonnie M., additional, Tran, Ursula, additional, Joyce, M. Gordon, additional, Georgiev, Ivelin S., additional, Rolland, Morgane, additional, Thomas, Rasmi, additional, Tovanabutra, Sodsai, additional, Doria-Rose, Nicole A., additional, Polonis, Victoria R., additional, Mascola, John R., additional, McDermott, Adrian B., additional, Michael, Nelson L., additional, Robb, Merlin L., additional, and Krebs, Shelly J., additional

Published
2021
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34. Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes

Author

Garcia-Bates, Tatiana M., primary, Palma, Mariana L., additional, Anderko, Renee R., additional, Hsu, Denise C., additional, Ananworanich, Jintanat, additional, Korber, Bette T., additional, Gaiha, Gaurav D., additional, Phanuphak, Nittaya, additional, Thomas, Rasmi, additional, Tovanabutra, Sodsai, additional, Walker, Bruce D., additional, Mellors, John W., additional, Piazza, Paolo A., additional, Kroon, Eugene, additional, Riddler, Sharon A., additional, Michael, Nelson L., additional, Rinaldo, Charles R., additional, and Mailliard, Robbie B., additional

Published
2021
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36. Dendritic Cells Focus CTL Responses Toward Highly Conserved and Topologically Important HIV Epitopes

Author

Garcia-Bates, Tatiana M., primary, Palma, Mariana L., additional, Hsu, Denise C., additional, Ananworanich, Jintanat, additional, Korber, Bette T., additional, Gaiha, Gaurav D., additional, Phanuphak, Nittaya, additional, Thomas, Rasmi, additional, Tovanabutra, Sodsai, additional, Walker, Bruce D., additional, Mellors, John W., additional, Piazza, Paolo A., additional, Kroon, Eugene, additional, Riddler, Sharon A., additional, Michael, Nelson L., additional, Rinaldo, Charles R., additional, and Mailliard, Robbie B., additional

Published
2020
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38. A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials

Author

Ehrenberg, Philip K., primary, Shangguan, Shida, additional, Issac, Biju, additional, Alter, Galit, additional, Geretz, Aviva, additional, Izumi, Taisuke, additional, Bryant, Christopher, additional, Eller, Michael A., additional, Wegmann, Frank, additional, Apps, Richard, additional, Creegan, Matthew, additional, Bolton, Diane L., additional, Sekaly, Rafick P., additional, Robb, Merlin L., additional, Gramzinski, Robert A., additional, Pau, Maria G., additional, Schuitemaker, Hanneke, additional, Barouch, Dan H., additional, Michael, Nelson L., additional, and Thomas, Rasmi, additional

Published
2019
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40. Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial

Author

Crowell, Trevor A, primary, Colby, Donn J, additional, Pinyakorn, Suteeraporn, additional, Sacdalan, Carlo, additional, Pagliuzza, Amélie, additional, Intasan, Jintana, additional, Benjapornpong, Khunthalee, additional, Tangnaree, Kamonkan, additional, Chomchey, Nitiya, additional, Kroon, Eugène, additional, de Souza, Mark S, additional, Tovanabutra, Sodsai, additional, Rolland, Morgane, additional, Eller, Michael A, additional, Paquin-Proulx, Dominic, additional, Bolton, Diane L, additional, Tokarev, Andrey, additional, Thomas, Rasmi, additional, Takata, Hiroshi, additional, Trautmann, Lydie, additional, Krebs, Shelly J, additional, Modjarrad, Kayvon, additional, McDermott, Adrian B, additional, Bailer, Robert T, additional, Doria-Rose, Nicole, additional, Patel, Bijal, additional, Gorelick, Robert J, additional, Fullmer, Brandie A, additional, Schuetz, Alexandra, additional, Grandin, Pornsuk V, additional, O'Connell, Robert J, additional, Ledgerwood, Julie E, additional, Graham, Barney S, additional, Tressler, Randall, additional, Mascola, John R, additional, Chomont, Nicolas, additional, Michael, Nelson L, additional, Robb, Merlin L, additional, Phanuphak, Nittaya, additional, Ananworanich, Jintanat, additional, Ake, Julie A., additional, Akapirat, Siriwat, additional, Bose, Meera, additional, Cale, Evan, additional, Chan, Phillip, additional, Chanthaburanun, Sararut, additional, Churikanont, Nampueng, additional, Dawson, Peter, additional, Dumrongpisutikul, Netsiri, additional, Getchalarat, Saowanit, additional, Jongrakthaitae, Surat, additional, Jongsakul, Krisada, additional, Lerdlum, Sukalaya, additional, Manasnayakorn, Sopark, additional, McCullough, Corinne, additional, Milazzo, Mark, additional, Nuntapinit, Bessara, additional, On, Kier, additional, Ouellette, Madelaine, additional, Phanuphak, Praphan, additional, Sanders-Buell, Eric, additional, Sangnoi, Nongluck, additional, Shangguan, Shida, additional, Sirivichayakul, Sunee, additional, Tragonlugsana, Nipattra, additional, Trichavaroj, Rapee, additional, Ubolyam, Sasiwimol, additional, Vasan, Sandhya, additional, Wattanaboonyongcharoen, Phandee, additional, and Yamchuenpong, Thipvadee, additional

Published
2019
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41. OR21 HLA-C downregulation by HIV adapts to host HLA genotype

Author

Apps, Richard, primary, Bachtel, Nathaniel, additional, Umviligihozo, Gisele, additional, Pickering, Suzanne, additional, Mota, Talia, additional, Liang, Hua, additional, Prete, Gregory Del, additional, Chatterjee, Pramita, additional, Lee, Guinevere, additional, Thomas, Rasmi, additional, Brockman, Mark, additional, Neil, Stuart, additional, Carrington, Mary, additional, Bwana, Bosco, additional, Bangsberg, David, additional, Martin, Jeffrey, additional, Kallas, Esper, additional, Donini, Camila, additional, Cerqueira, Natalia, additional, O’Doherty, Una, additional, Hahn, Beatrice, additional, Jones, Brad, additional, Brumme, Zabrina, additional, and Nixon, Douglas, additional

Published
2018
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45. Determinants of CD8+ T Cell Immunodominance in Acute HIV-1 Infection

Author

Warren, Joanna A., primary, Xu, Yinyan, additional, Constanzo, Margaret, additional, Whale, Victoria, additional, Liu, Michael, additional, Thomas, Rasmi, additional, Tovanabutra, Sodsai, additional, Kijak, Gustavo H., additional, Eller, Leigh A., additional, Rolland, Morgane, additional, Michael, Nelson L., additional, Robb, Merlin L., additional, Eller, Michael A., additional, and Goonetilleke, Nilu, additional

Published
2018
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46. HIV-1-Specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galactosylceramide Blocking and Phagocytosis

Author

Wills, Saintedym, primary, Hwang, Kwan-Ki, additional, Liu, Pinghuang, additional, Dennison, S. Moses, additional, Tay, Matthew Zirui, additional, Shen, Xiaoying, additional, Pollara, Justin, additional, Lucas, Judith T., additional, Parks, Robert, additional, Rerks-Ngarm, Supachai, additional, Pitisuttithum, Punnee, additional, Nitayapan, Sorachai, additional, Kaewkungwal, Jaranit, additional, Thomas, Rasmi, additional, Kim, Jerome H., additional, Michael, Nelson L., additional, Robb, Merlin L., additional, McRaven, Mike, additional, Montefiori, David C., additional, Hope, Thomas J., additional, Liao, Hua-Xin, additional, Moody, M. Anthony, additional, Ferrari, Guido, additional, Haynes, Barton F., additional, Alam, S. Munir, additional, Bonsignori, Mattia, additional, and Tomaras, Georgia D., additional

Published
2018
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47. Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

Author

Kijak, Gustavo H., primary, Sanders-Buell, Eric, additional, Chenine, Agnes-Laurence, additional, Eller, Michael A., additional, Goonetilleke, Nilu, additional, Thomas, Rasmi, additional, Leviyang, Sivan, additional, Harbolick, Elizabeth A., additional, Bose, Meera, additional, Pham, Phuc, additional, Oropeza, Celina, additional, Poltavee, Kultida, additional, O’Sullivan, Anne Marie, additional, Billings, Erik, additional, Merbah, Melanie, additional, Costanzo, Margaret C., additional, Warren, Joanna A., additional, Slike, Bonnie, additional, Li, Hui, additional, Peachman, Kristina K., additional, Fischer, Will, additional, Gao, Feng, additional, Cicala, Claudia, additional, Arthos, James, additional, Eller, Leigh A., additional, O’Connell, Robert J., additional, Sinei, Samuel, additional, Maganga, Lucas, additional, Kibuuka, Hannah, additional, Nitayaphan, Sorachai, additional, Rao, Mangala, additional, Marovich, Mary A., additional, Krebs, Shelly J., additional, Rolland, Morgane, additional, Korber, Bette T., additional, Shaw, George M., additional, Michael, Nelson L., additional, Robb, Merlin L., additional, Tovanabutra, Sodsai, additional, and Kim, Jerome H., additional

Published
2017
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49. Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

Author

Kijak, Gustavo H., primary, Sanders-Buell, Eric, additional, Chenine, Agnes-Laurence, additional, Eller, Michael A., additional, Goonetilleke, Nilu, additional, Thomas, Rasmi, additional, Leviyang, Sivan, additional, Harbolick, Elizabeth A., additional, Bose, Meera, additional, Pham, Phuc, additional, Oropeza, Celina, additional, Poltavee, Kultida, additional, O’Sullivan, Anne Marie, additional, Billings, Erik, additional, Merbah, Melanie, additional, Costanzo, Margaret C., additional, Warren, Joanna A., additional, Slike, Bonnie, additional, Li, Hui, additional, Peachman, Kristina K., additional, Fischer, Will, additional, Gao, Feng, additional, Cicala, Claudia, additional, Arthos, James, additional, Eller, Leigh A., additional, O’Connell, Robert J., additional, Sinei, Samuel, additional, Maganga, Lucas, additional, Kibuuka, Hannah, additional, Nitayaphan, Sorachai, additional, Rao, Mangala, additional, Marovich, Mary A., additional, Krebs, Shelly J., additional, Rolland, Morgane, additional, Korber, Bette T., additional, Shaw, George M., additional, Michael, Nelson L., additional, Robb, Merlin L., additional, Tovanabutra, Sodsai, additional, and Kim, Jerome H., additional

Published
2017
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50. Understanding the determinants of CD8+ T cell immunodominance in acute HIV infection

Author

Warren, Joanna A, primary, Xu, Yinyan, additional, Costanzo, Margaret, additional, Whale, Victoria, additional, Liu, Michael P.K., additional, Thomas, Rasmi, additional, Tovanabutra, Sodsai, additional, Kijak, Gustavo, additional, Eller, Leigh Anne, additional, Rolland, Morgane, additional, Michael, Nelson L., additional, Robb, Merlin L., additional, Eller, Michael A., additional, and Goonetilleke, Nilu, additional

Published
2017
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