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1. Proceedings of the Virtual 3rd UK Implementation Science Research Conference

Author

Noura Bawab, Joanna C. Moullin, Olivier Bugnon, Clémence Perraudin, April Morrow, Priscilla Chan, Emily Hogden, Natalie Taylor, Mark Pearson, Daniele Carrieri, Karen Mattick, Chrysanthi Papoutsi, Simon Briscoe, Geoff Wong, Mark Jackson, Alita Rushton, Kai Elmas, Jack Bell, Agnes Binagwaho, Miriam F. Frisch, Jovial Thomas Ntawukuriryayo, Dieudonné Nkurunziza, Kelechi Udoh, Amy VanderZanden, Laura Drown, Lisa R. Hirschhorn, N. Seward, C. Hanlon, N. Sevdalis, Mike Hurley, Sally Irwin, Jo Erwin, Fay Sibley, Amber Gibney, Andrea Carter, M. Hurley, M. Connelly, H. Sheldon, A. Gibney, R. Hallett, A. Carter, T. Colbourn, J. Murdoch, M. Prince, S. Venkatapuram, Chelsea Coumoundouros, Erika Mårtensson, Giulia Ferraris, Louise von Essen, Robbert Sanderman, Joanne Woodford, W. Slemming, R. Drysdale, T. Makusha, L. Richter, Pallari Elena, Kristina Medlinskiene, Justine Tomlinson, Iuri Marques, Susan Richardson, Katherine Striling, Duncan Petty, Humma Andleeb, Aislinn Bergin, Dan Robotham, Sue Brown, Jennifer Martin, Tayana Soukup, Louise Hull, Ioannis Bakolis, Andy Healey, Dulmini Kariyawasam, Augustin Brooks, Simon Heller, Stephanie Amiel, Nick Sevdalis, People with Diabetes Group, Zuhur Balayah, Zarnie Khadjesari, Aoife Keohane, Wilson To, James S. A. Green, Hossai Gul, Janet Long, Stephani Best, Frances Rapport, Jeffrey Braithwaite, Shalini Ahuja, Gregory Godwin, Gabriel Birgand, Andrew Leather, Sanjeev Singh, V. Pranav, Nathan Peiffer-Smadja, Esmita Charani, Alison Holmes, on behalf of co-investigators of ASPIRES, Kimberly Peven, Michelle White, Marc Mendelson, ASPIRES study coinvestigators, Jackie Dwane, Sean Redmond, Eoin O’Meara Daly, Caitlin Lewis, Julia E. Moore, Sobia Khan, Alexandra Ridout, Venetia Goodhart, Sophie Bright, Sattu Issa, Betty Sam, Jane Sandall, Andrew Shennan, Carlos Alberto dos Santos Treichel, Rosana Teresa Onocko Campos, Alice Coffey, Helen Flanagan, Martina O’Reilly, Valerie O’Reilly, Pauline Meskell, Maria Bailey, Eileen Carey, Jane O’Doherty, Cathy Payne, Karen Charnley, Dennis H. Li, Nanette Benbow, J. D. Smith, Juan Villamar, Brennan Keiser, Melissa Mongrella, Thomas Remble, Brian Mustanski, Celia Laur, Ann Marie Corrado, Jeremy Grimshaw, Noah Ivers, N. Benbow, K. Macapagal, J. Jones, K. Madkins, D. H. Li, B. Mustanski, Logan Manikam, Shereen Allaham, Michelle Heys, Clare Llewellyn, Neha Batura, Andrew Hayward, Yasmin Bou Karim, Jenny Gilmour, Kelley Webb-Martin, Carol Irish, Chanel Edwards, Monica Lakhanpaul, Paulina Daw, Jet Veldhuijzen van Zanten, Alexander Harrison, Hasnain Dalal, Rod S. Taylor, Patrick J. Doherty, Sinead T. J. McDonagh, Colin J. Greaves, Michelle C. White, Andrew J. M. Leather, Ben Grodzinski, Harry Bestwick, Faheem Bhatti, Rory Durham, Maaz Khan, Celine Partha-Sarathi, Jye Quan Teh, Oliver Mowforth, Benjamin M. Davies, On behalf of AO Spine RECODE-DCM Consortia, Michael Sykes, Richard Thomson, Niina Kolehmainen, Louise Allan, Tracy Finch, S. Hogervorst, M. C. Adriaanse, H. E. Brandt, M. Vervloet, L. van Dijk, J. G. Hugtenburg, Nataliya Brima, T. B. Kamara, H. Wurie, K. Daoh, B. Deen, Justine Davies, Jennifer Shuldiner, Nida Shah, Paul C. Nathan, Susan Calnan, Caragh Flannery, Sheena McHugh, Tracey Brown, Alex Ramsey, Henry Goodfellow, Sherine El-Toukhy, Lorien Abroms, Helena Jopling, Michael Amato, Magdalena Jurczuk, Posy Bidwell, Daniel Wolstenholme, Louise Silverton, Jan Van Der Meulen, Ipek Gurol-Urganci, Ranee Thakar, Andreas Xyrichis, Katerina Iliopoulou, Jessica McCluskey, Patricia Donnelly, Sarah Brady, Sue Franklin, Carol-Anne Murphy, Emma Smith, Emma Belton, Katherine Jeays-Ward, Matt Willox, Nicki Barker, Pete Metherall, Avril McCarthy, Heath Read, and Heather Elphick

Subjects
Medicine (General), R5-920
Published
2020
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2. Assessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial: baseline characteristics

Author

M. Thomas, M. Leija, L. Cedo, K. Turner, Kurt T. Barnhart, Awoniyi O. Awonuga, Joel W. Ager, R. Ladda, M. Singh, Yufeng Jin, P. Turek, M. Yoscovits, Elizabeth E. Puscheck, Carol L. Gnatuk, M. Rhea, R. Marunich, A. Cline, Gloria Cheng, N. Di Maria, J. Ober, M. Brennan, Hongying Kuang, C. Zornes, K. Lecks, Thomas Remble, Karl R. Hansen, L. Sakai, Yolanda R. Smith, Christos Coutifaris, M. Ringbloom, Aimee Seungdamrong, Hao Huang, M. Crow, Hugh S. Taylor, R. Mitchell Rosen, Stephanie J. Estes, L. De Paolo, P. Patrizio, Gregory M. Christman, Robert G. Brzyski, Tracey Thomas, Vanja Dukic, A. Hernandez, Amy H. Herring, J. C. Trussell, Karen Collins, Y. Li, Randal D. Robinson, Nanette Santoro, M. R. Rodriguez, LaTasha B. Craig, Jean Wactawski-Wende, Qingshang Yan, Valerie L. Baker, Senait Fisseha, L. Martinez, D. Del Basso, Rebecca S. Usadi, David S. Guzick, M. Zhang, V. Lewis, William C. Dodson, B. Laylor, C. Lamar, J. Bruce Redmond, G. Wright Bates, Stephen A. Krawetz, Heping Zhang, Robert W. Rebar, C. Bartlebaugh, Michael P. Diamond, Daniel Haisonleder, A. Comfort, Peter Casson, F. Witter, C. Song, A. Hohmann, C. Easton, Andrea Wojtczuk, Lauri Green, T. S. Hunt, L. Martino, Nikolaus Lenhart, P. Cato, S. Mallette, Richard S. Legro, S. Mason, Esther Eisenberg, John F. Randolph, J. Tang, Ruben Alvero, Peter N. Schlegel, A. Solnica, and D. Pierce

Subjects
Infertility, Adult, Male, medicine.medical_specialty, medicine.drug_class, medicine.medical_treatment, Clomiphene, Ovulation Induction, Pregnancy, Nitriles, Medicine, Humans, Ovarian reserve, Unexplained infertility, Gynecology, Aromatase inhibitor, business.industry, Letrozole, Female infertility, Pregnancy Outcome, Obstetrics and Gynecology, Fertility Agents, Female, Triazoles, medicine.disease, Antral follicle, Reproductive Medicine, Quality of Life, Ovulation induction, Female, Pregnancy, Multiple, business, Infertility, Female, Gonadotropins, medicine.drug
Abstract

To identify baseline characteristics of women with unexplained infertility to determine whether treatment with an aromatase inhibitor will result in a lower rate of multiple gestations than current standard ovulation induction medications.Randomized, prospective clinical trial.Multicenter university-based clinical practices.A total of 900 couples with unexplained infertility.Collection of baseline demographics, blood samples, and ultrasonographic assessments.Demographic, laboratory, imaging, and survey characteristics.Demographic characteristics of women receiving clomiphene citrate (CC), letrozole, or gonadotropins for ovarian stimulation were very consistent. Their mean age was 32.2 ± 4.4 years and infertility duration was 34.7 ± 25.7 months, with 59% primary infertility. More than one-third of the women were current or past smokers. The mean body mass index (BMI) was 27 and mean antimüllerian hormone level was 2.6; only 11 women (1.3%) had antral follicle counts of5. Similar observations were identified for hormonal profiles, ultrasound characterization of the ovaries, semen parameters, and quality of life assessments in both male and female partners.The cause of infertility in the couples recruited to this treatment trial is elusive, as the women were regularly ovulating and had evidence of good ovarian reserve both by basal FSH, antimüllerian hormone levels, and antral follicle counts; the male partners had normal semen parameters. The three treatment groups have common baseline characteristics, thereby providing comparable patient populations for testing the hypothesis that use of letrozole for ovarian stimulation can reduce the rates of multiples from that observed with gonadotropin and CC treatment.NCT 01044862.

Published
2014

3. Virtual conference. 16 and 17 July 2020

Author

Noura Bawab, Joanna C. Moullin, Olivier Bugnon, Clémence Perraudin, April Morrow, Priscilla Chan, Emily Hogden, Natalie Taylor, Mark Pearson, Daniele Carrieri, Karen Mattick, Chrysanthi Papoutsi, Simon Briscoe, Geoff Wong, Mark Jackson, Alita Rushton, Kai Elmas, Jack Bell, Agnes Binagwaho, Miriam F. Frisch, Jovial Thomas Ntawukuriryayo, Dieudonné Nkurunziza, Kelechi Udoh, Amy VanderZanden, Laura Drown, Lisa R. Hirschhorn, N. Seward, C. Hanlon, N. Sevdalis, Mike Hurley, Sally Irwin, Jo Erwin, Fay Sibley, Amber Gibney, Andrea Carter, M. Hurley, M. Connelly, H. Sheldon, A. Gibney, R. Hallett, A. Carter, T. Colbourn, J. Murdoch, M. Prince, S. Venkatapuram, Chelsea Coumoundouros, Erika Mårtensson, Giulia Ferraris, Louise von Essen, Robbert Sanderman, Joanne Woodford, W. Slemming, R. Drysdale, T. Makusha, L. Richter, Pallari Elena, Kristina Medlinskiene, Justine Tomlinson, Iuri Marques, Susan Richardson, Katherine Striling, Duncan Petty, Humma Andleeb, Aislinn Bergin, Dan Robotham, Sue Brown, Jennifer Martin, Tayana Soukup, Louise Hull, Ioannis Bakolis, Andy Healey, Dulmini Kariyawasam, Augustin Brooks, Simon Heller, Stephanie Amiel, Nick Sevdalis, People with Diabetes Group, Zuhur Balayah, Zarnie Khadjesari, Aoife Keohane, Wilson To, James S. A. Green, Hossai Gul, Janet Long, Stephani Best, Frances Rapport, Jeffrey Braithwaite, Shalini Ahuja, Gregory Godwin, Gabriel Birgand, Andrew Leather, Sanjeev Singh, V. Pranav, Nathan Peiffer-Smadja, Esmita Charani, Alison Holmes, on behalf of co-investigators of ASPIRES, Kimberly Peven, Michelle White, Marc Mendelson, ASPIRES study coinvestigators, Jackie Dwane, Sean Redmond, Eoin O’Meara Daly, Caitlin Lewis, Julia E. Moore, Sobia Khan, Alexandra Ridout, Venetia Goodhart, Sophie Bright, Sattu Issa, Betty Sam, Jane Sandall, Andrew Shennan, Carlos Alberto dos Santos Treichel, Rosana Teresa Onocko Campos, Alice Coffey, Helen Flanagan, Martina O’Reilly, Valerie O’Reilly, Pauline Meskell, Maria Bailey, Eileen Carey, Jane O’Doherty, Cathy Payne, Karen Charnley, Dennis H. Li, Nanette Benbow, J. D. Smith, Juan Villamar, Brennan Keiser, Melissa Mongrella, Thomas Remble, Brian Mustanski, Celia Laur, Ann Marie Corrado, Jeremy Grimshaw, Noah Ivers, N. Benbow, K. Macapagal, J. Jones, K. Madkins, D. H. Li, B. Mustanski, Logan Manikam, Shereen Allaham, Michelle Heys, Clare Llewellyn, Neha Batura, Andrew Hayward, Yasmin Bou Karim, Jenny Gilmour, Kelley Webb-Martin, Carol Irish, Chanel Edwards, Monica Lakhanpaul, Paulina Daw, Jet Veldhuijzen van Zanten, Alexander Harrison, Hasnain Dalal, Rod S. Taylor, Patrick J. Doherty, Sinead T. J. McDonagh, Colin J. Greaves, Michelle C. White, Andrew J. M. Leather, Ben Grodzinski, Harry Bestwick, Faheem Bhatti, Rory Durham, Maaz Khan, Celine Partha-Sarathi, Jye Quan Teh, Oliver Mowforth, Benjamin M. Davies, On behalf of AO Spine RECODE-DCM Consortia, Michael Sykes, Richard Thomson, Niina Kolehmainen, Louise Allan, Tracy Finch, S. Hogervorst, M. C. Adriaanse, H. E. Brandt, M. Vervloet, L. van Dijk, J. G. Hugtenburg, Nataliya Brima, T. B. Kamara, H. Wurie, K. Daoh, B. Deen, Justine Davies, Jennifer Shuldiner, Nida Shah, Paul C. Nathan, Susan Calnan, Caragh Flannery, Sheena McHugh, Tracey Brown, Alex Ramsey, Henry Goodfellow, Sherine El-Toukhy, Lorien Abroms, Helena Jopling, Michael Amato, Magdalena Jurczuk, Posy Bidwell, Daniel Wolstenholme, Louise Silverton, Jan Van Der Meulen, Ipek Gurol-Urganci, Ranee Thakar, Andreas Xyrichis, Katerina Iliopoulou, Jessica McCluskey, Patricia Donnelly, Sarah Brady, Sue Franklin, Carol-Anne Murphy, Emma Smith, Emma Belton, Katherine Jeays-Ward, Matt Willox, Nicki Barker, Pete Metherall, Avril McCarthy, Heath Read, and Heather Elphick

Subjects
lcsh:R5-920, lcsh:Medicine (General), Meeting Abstracts
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