312 results on '"Thompson, Chad M."'
Search Results
2. Assessment of the genotoxicity of tert‐butyl alcohol in an in vivo thyroid comet assay
3. Comparison of transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in wild-type and PPARα knockout mouse hepatocytes.
4. Comparison of transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in mouse, rat, and pooled human hepatocytes.
5. Inhalation cancer risk assessment for environmental exposure to hexavalent chromium: Comparison of margin-of-exposure and linear extrapolation approaches
6. Exposure to environmentally-relevant concentrations of hexavalent chromium does not induce ovarian toxicity in mice
7. Comparison of threshold of toxicological concern (TTC) values to oral reference dose (RfD) values
8. Assessment of the in vivo genotoxic potential of three smoke flavoring primary product mixtures
9. Letter to the editor of environmental pollution: In regard to Wan et al. (2024) “GenX caused liver injury and potential hepatocellular carcinoma of mice via drinking water even at environmental concentration”
10. Hexavalent Chromium in Drinking Water
11. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans
12. An Adverse Outcome Pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events
13. A putative adverse outcome network for neonatal mortality and lower birth weight in rodents: Applicability to per‐ and polyfluoroalkyl substances and relevance to human health
14. Letter to “Chepelev et al. Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogenicity dose–response data”
15. Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations
16. Assessment of Mouse Liver Histopathology Following Exposure to HFPO-DA With Emphasis on Understanding Mechanisms of Hepatocellular Death
17. Assessment of the mode of action underlying development of liver lesions in mice following oral exposure to HFPO-DA and relevance to humans
18. Inhalation cancer risk assessment of cobalt metal
19. Assessment of the mode of action for hexavalent chromium-induced lung cancer following inhalation exposures
20. High concentrations of hexavalent chromium in drinking water alter iron homeostasis in F344 rats and B6C3F1 mice
21. Evaluation of Transcriptomic Responses in Livers of Mice Exposed to the Short-Chain PFAS Compound HFPO-DA
22. Assessment of the mutagenic potential of hexavalent chromium in the duodenum of big blue® rats
23. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum: An in silico comparison with mutagenic and nonmutagenic carcinogens across tissues
24. Crypt and Villus Transcriptomic Responses in Mouse Small Intestine Following Oral Exposure to Hexavalent Chromium
25. A review of mammalian in vivo genotoxicity of hexavalent chromium: implications for oral carcinogenicity risk assessment
26. Development of updated RfD and RfC values for medium carbon range aromatic and aliphatic total petroleum hydrocarbon fractions
27. A robust method for assessing chemically induced mutagenic effects in the oral cavity of transgenic Big Blue® rats
28. Assessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue® transgenic F344 rats
29. Synchrotron-Based Imaging of Chromium and γ-H2AX Immunostaining in the Duodenum Following Repeated Exposure to Cr(VI) in Drinking Water
30. Renal clearance parameters for PBPK model analysis of early lifestage differences in the disposition of environmental toxicants
31. Assessment of Mechanistic Data for Hexavalent Chromium-Induced Rodent Intestinal Cancer Using the Key Characteristics of Carcinogens
32. A Genomics-Based Analysis of Relative Potencies of Dioxin-Like Compounds in Primary Rat Hepatocytes
33. Supplemental Material, Supplemental_Figure_Legends - Assessment of the Mode of Action Underlying the Effects of GenX in Mouse Liver and Implications for Assessing Human Health Risks
34. Using mechanistic information to support evidence integration and synthesis: a case study with inhaled formaldehyde and leukemia
35. An updated mode of action and human relevance framework evaluation for Formaldehyde-Related nasal tumors
36. An approach for integrating toxicogenomic data in risk assessment: The dibutyl phthalate case study
37. Utilizing toxicogenomic data to understand chemical mechanism of action in risk assessment
38. Crypt and Villus Transcriptomic Responses in Mouse Small Intestine Following Oral Exposure to Hexavalent Chromium.
39. Comparative toxicogenomic analysis of oral Cr(VI) exposure effects in rat and mouse small intestinal epithelia
40. Duodenal GSH/GSSG Ratios in Mice Following Oral Exposure to Cr(VI)
41. Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90 days of exposure to hexavalent chromium in drinking water
42. Comparison of the Effects of Hexavalent Chromium in the Alimentary Canal of F344 Rats and B6C3F1 Mice Following Exposure in Drinking Water: Implications for Carcinogenic Modes of Action
43. Investigation of the Mode of Action Underlying the Tumorigenic Response Induced in B6C3F1 Mice Exposed Orally to Hexavalent Chromium
44. A response to “A quantitative assessment of the carcinogenicity of hexavalent chromium by the oral route and its relevance to human exposure”
45. Considerations for the Implausibility of Leukemia Induction by Formaldehyde
46. Application of the U.S. EPA Mode of Action Framework for Purposes of Guiding Future Research: A Case Study Involving the Oral Carcinogenicity of Hexavalent Chromium
47. An adverse outcome pathway for small intestinal tumors in mice involving chronic cytotoxicity and regenerative hyperplasia: a case study with hexavalent chromium, captan, and folpet
48. Assessment of the Mode of Action Underlying the Effects of GenX in Mouse Liver and Implications for Assessing Human Health Risks
49. Mechanistic and dose considerations for supporting adverse pulmonary physiology in response to formaldehyde
50. Comparison of Gene Expression Responses in the Small Intestine of Mice Following Exposure to 3 Carcinogens Using the S1500+ Gene Set Informs a Potential Common Adverse Outcome Pathway
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