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The purpose of this study was to explore the changes in blood cellular and biochemical parameters of rats in a natural environment of low pressure and low oxygen on the plateau. Male Sprague-Dawley rats in two groups were raised in different environments from 4 weeks of age for a period of 24 weeks. They were raised to 28 weeks of age and then transported to the plateau medical laboratory of Qinghai University. Blood cellular and biochemical parameters were measured and the data of the two groups were statistically analyzed. 1. RBC in the HA group was higher than that in the Control group, but there was no significant difference between the two groups (p > 0.05), Compared with the Control group, HGB, MCV, MCH, MCHC and RDW in the HA group were significantly higher (p < 0.05). 2. Compared with the Control group, WBC, LYMP, EO, LYMP% and EO% in the HA group decreased significantly (p < 0.05), and ANC% increased significantly (p < 0.05). 3. In the platelet index, compared with the Control group, PLT in the HA group was significantly reduced (p < 0.05), PDW, MRV, P-LCR were significantly increased (p < 0.05). 4. In blood biochemical indicators, compared with the Control group, AST, TBIL, IBIL, LDH in the HA group decreased significantly (p < 0.05), CK in the HA group increased significantly (p < 0.05). 1. The indexes related to red blood cells, white blood cells, platelets and some biochemical indexes in the blood of rats at high altitude have changed. 2. Under the high altitude environment, the oxygen carrying capacity of SD rats is improved, the resistance to disease may be reduced, the coagulation and hemostasis functions may be affected, and there is a risk of bleeding. The liver function, renal function, heart function and skeletal muscle energy metabolism may be affected. 3. This study can provide an experimental basis for the research on the pathogenesis of high-altitude diseases from the perspective of blood. In this study, red blood cells, white blood cells, platelets and blood biochemical indicators were included in the real plateau environment to comprehensively analyze the changes of blood cellular and biochemical parameters in rats under the chronic plateau hypobaric hypoxia environment. From the perspective of blood, this study can provide an experimental basis for research on the pathogenesis of high-altitude diseases. Explore the data support of oxygen-carrying capacity, disease resistance and energy metabolism of the body in the natural environment at high altitude. [ABSTRACT FROM AUTHOR]

In the present paper, computational fluid dynamic modelings were established to research a newly presented re-heat steam temperature deviation solution on the basis of FLUENT 6.3.26 considering a 700 MWe tangentially fired pulverised-coal boiler, which confronted with severe flue gas and re-heat steam temperature deviation. The model was solidly validated by grid independence test and comparison with the experimental data obtained from a series of on-site measurements. Upon reliable validation, the model was further used to investigate the forming mechanism of re-heat steam temperature deviation as well as the influence of burner tilt angle on it. The conclusions mainly include (1) Residual swirling flow in the upper furnace caused the flue gas velocity and temperature deviations in crossover pass. For a typical anticlockwise tangential firing system, the flue gas velocity and temperature were lower in left part of crossover pass. The deviation of flue gas further generated the convective heat transfer imbalance of final re-heater, therefore, the temperature deviation of re-heat steam was severe. (2) Tilting the burner upward can effectively reduce the intensity of residual flow as well as the flue gas deviation degree. The + 11° tilt angle of burner was relatively optimum considering the flue gas deviation and final re-heater overheating potential. Specifically, the intensity of residual swirl flow dropped 44% with burner tilting upward for + 11°. Practical operation of boiler demonstrated that the reheat steam temperature deviation was reduced from 22 °C to 10 °C in this case. (3) When the tilt angle of additional air (AA) was bias set, the flow field of upper furnace was changed. Consequently, the residual swirl flow intensity and the flue gas deviation were reduced considerably. On-site measurements indicated that the combination of tilting burner upward for + 11° and setting the bias of AA tilt angle for 10° can further reduce the re-heat steam temperature deviation to 4 °C. [ABSTRACT FROM AUTHOR]