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Image segmentation is an important part of image processing. The result of image segmentation directly affects the effect of subsequent image processing. However the efficiency of the traditional maximum class variance method is low. This paper uses the cuckoo algorithm to optimize the traditional maximum class variance method to achieve a better segmentation effect. This image segmentation method combined with optimization theory can achieve the purpose of finding the optimal segmentation.

In order to solve the shortcomings of traditional Sobel edge detection operator, such as low accuracy of image edge location and rough edge extracted, an improved edge detection algorithm based on Sobel operator is proposed. Firstly, in the aspect of the accuracy of edge detection, the direction template is increased from two directions of horizontal and vertical to eight directions; secondly, in terms of the rough edge extracted and the noise sensitivity, combined with the operation of mathematical morphology, the edge can be refined, and at the same time, some part of the noise can be suppressed. The experiment results show that the improved edge detection algorithm has a better accuracy in image positioning, and a certain ability to suppress noise. Finally, the detected image edge of the image is more delicate and clear than the traditional Sobel operator.

We tested the possibility that proteasome inhibition may reverse preexisting cardiac hypertrophy and improve remodeling upon pressure overload. Mice were submitted to aortic banding and followed up for 3 wk. The proteasome inhibitor epoxomicin (0.5 mg/kg) or the vehicle was injected daily, starting 2 wk after banding. At the end of the third week, vehicle-treated banded animals showed significant (P < 0.05) increase in proteasome activity (PA), left ventricle-to-tibial length ratio (LV/TL), myocyte cross-sectional area (MCA), and myocyte apoptosis compared with sham-operated animals and developed signs of heart failure, including increased lung weight-to-TL ratio and decreased ejection fraction. When compared with that group, banded mice treated with epoxomicin showed no increase in PA, a lower LV/TL and MCA, reduced apoptosis, stabilized ejection fraction, and no signs of heart failure. Because overload-mediated cardiac remodeling largely depends on the activation of the proteasome-regulated transcription factor NF-[kappa]B, we tested whether epoxomicin would prevent this activation. NF-[kappa]B activity increased significantly upon overload, which was suppressed by epoxomicin. The expression of NF-[kappa]B-dependent transcripts, encoding collagen types I and III and the matrix metalloprotease-2, increased (P < 0.05) after banding, which was abolished by epoxomicin. The accumulation of collagen after overload, as measured by histology, was 75% lower (P < 0.05) with epoxomicin compared with vehicle. Myocyte apoptosis increased by fourfold in hearts submitted to aortic banding compared with sham-operated hearts, which was reduced by half upon epoxomicin treatment. Therefore, we propose that proteasome inhibition after the onset of pressure overload rescues ventricular remodeling by stabilizing cardiac function, suppressing further progression of hypertrophy, repressing collagen accumulation, and reducing myocyte apoptosis. collagen; nuclear factor-[kappa]B

This thesis aims to analyse the deposit characteristics about Da Hong Mountains Iron ore in Yunnan province. The texture and structure, especially the chemical composition, is different in every section of deposit after comparing. Moreover, the content of SiO2 is much higher than general iron ore. However, the content of other noble metals cannot reach the lowest industrial grade. Da Hong Mountains Iron ore has unique features because of metallogenic periods.