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1. DNA replication in early mammalian embryos is patterned, predisposing lamina-associated regions to fragility

2. Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma

3. Correction: Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group’s clinical trial E3999

4. Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group’s clinical trial E3999

5. Disruption of the crypt niche promotes outgrowth of mutated colorectal tumor stem cells

6. Novel insights into breast cancer copy number genetic heterogeneity revealed by single-cell genome sequencing

7. Ordered and deterministic cancer genome evolution after p53 loss

8. Supplementary Data from MYC Levels Regulate Metastatic Heterogeneity in Pancreatic Adenocarcinoma

9. Data from MYC Levels Regulate Metastatic Heterogeneity in Pancreatic Adenocarcinoma

10. Supplementary Figure from MYC Levels Regulate Metastatic Heterogeneity in Pancreatic Adenocarcinoma

11. Supplementary Table 1 from Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition

12. Supplementary Data from Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer Metastasis

13. Supplementary Table 2 from Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition

14. Data from Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition

15. Data from Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer Metastasis

16. Supplementary Data from Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition

17. Supplementary Tables S1-S3 from The Genomic Landscape of Male Breast Cancers

18. Supplementary Methods from The Genomic Landscape of Male Breast Cancers

19. Supplementary Figures S4 and S5 from The Genomic Landscape of Male Breast Cancers

20. Supplementary Tables S11 and S12 from The Genomic Landscape of Male Breast Cancers

21. Data from The Genomic Landscape of Male Breast Cancers

22. Supplementary Figures S1-S3 from The Genomic Landscape of Male Breast Cancers

23. Clonal populations of a human TNBC model display significant functional heterogeneity and divergent growth dynamics in distinct contexts

24. MYC Levels Regulate Metastatic Heterogeneity in Pancreatic Adenocarcinoma

25. Chromosome 9p21.3 Coordinates Cell Intrinsic and Extrinsic Tumor Suppression

26. MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis

27. Mcm2 hypomorph leads to acute leukemia or hematopoietic stem cell failure, dependent on genetic context

28. Replication timing maintains the global epigenetic state in human cells

29. Abstract NG02: Ordered and selective patterns of cancer genome evolution revealed by lineage tracing of sporadic p53 loss

30. Abstract 3512: Organ-specific effects of Smad4 in metastatic pancreatic cancer

31. Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia

32. Replication Stress Impairs Chromosome Segregation and Preimplantation Development in Human Embryos

33. Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease

34. Measurable residual disease by flow cytometry in acute myeloid leukemia is prognostic, independent of genomic profiling

35. Phase and context shape the function of composite oncogenic mutations

36. Mapping Replication Timing in Single Mammalian Cells

37. Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer

38. BMP2/SMAD pathway activation in JAK2/p53-mutant megakaryocyte/erythroid progenitors promotes leukemic transformation

39. Disruption of the crypt niche promotes outgrowth of mutated colorectal tumor stem cells

40. Rapid phenotypic and genomic change in response to therapeutic pressure in prostate cancer inferred by high content analysis of single circulating tumor cells.

41. MYCcontrols metastatic heterogeneity in pancreatic cancer

42. DNA Breaks Due to Replication Stress Limit the Developmental Potential of Human Preimplantation Embryos

43. High resolution copy number inference in cancer using short-molecule nanopore sequencing

44. Novel insights into breast cancer copy number genetic heterogeneity revealed by single-cell genome sequencing

45. Leukemia cell of origin influences apoptotic priming and sensitivity to LSD1 inhibition

46. Author response: Novel insights into breast cancer copy number genetic heterogeneity revealed by single-cell genome sequencing

47. Mcm2 Deficiency Leads to Bone Marrow Failure and Lymphoid Malignancies Dependent on Age and Genetic Background

48. The BMP/SMAD Pathway Is a Key Mediator of Leukemic Transformation of TP53-Mutant Post-MPN AML

49. High resolution copy number inference in cancer using short-molecule nanopore sequencing

50. DNAJB1–PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma

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