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3. Secondary Prevention and Extreme Cardiovascular Risk Evaluation (SEVERE-1), Focus on Prevalence and Associated Risk Factors: The Study Protocol

Author

Maloberti, Alessandro, Intravaia, Rita Cristina Myriam, Mancusi, Costantino, Cesaro, Arturo, Golia, Enrica, Ilaria, Fucile, Coletta, Silvio, Merlini, Piera, De Chiara, Benedetta, Bernasconi, Davide, Algeri, Michela, Ossola, Paolo, Ciampi, Claudio, Riccio, Alfonso, Tognola, Chiara, Ardissino, Maddalena, Inglese, Elvira, Scaglione, Francesco, Calabrò, Paolo, De Luca, Nicola, and Giannattasio, Cristina

Published
2023
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5. Secondary prevention and extreme cardiovascular risk evaluation (SEVERE-0): Prevalence of extreme cardiovascular risk in cardiological rehabilitation patients and its impact on functional improvement

Author

Tognola, Chiara, Myriam Intravaia, Rita Cristina, Senini, Eleonora, Pezzoli, Stefano, Riccio, Alfonso, Gualini, Elena, Fabbri, Saverio, Bellantonio, Valentina, Politi, Francesco, Campana, Marta, Fucile, Ilaria, Mancusi, Costantino, Golia, Enrica, Cesaro, Arturo, De Luca, Nicola, Calabrò, Paolo, Giannattasio, Cristina, and Maloberti, Alessandro

Published
2024
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6. URIC ACID SIGNIFICANTLY CORRELATES WITH THE PRESENCE OF LOW-VOLTAGE AREAS AT THE ENDOCARDIAL MAPPING IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION

Author

Maloberti, Alessandro, primary, Baroni, Matteo, additional, Fortuna, Matteo, additional, Tognola, Chiara, additional, Algeri, Michela, additional, Intravaia, Rita Cristina My, additional, Leidi, Filippo, additional, Colombo, Valentina, additional, Ciampi, Claudio Mario, additional, Carbonaro, Marco, additional, Gigli, Lorenzo, additional, Mazzone, Patrizio, additional, Giannattasio, Cristina, additional, and Garofani, Ilaria, additional

Published
2024
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7. EFFECT OF ANTI-PCSK9 ANTIBODIES ON ARTERY STRUCTURE AND FUNCTION: THE NIGUARDA HOSPITAL COHORT

Author

Maloberti, Alessandro, primary, Toscani, Giorgio, additional, Busti, Andrea, additional, Tognola, Chiara, additional, Intravaia, Rita Cristina Mi, additional, De Censi, Lorenzo, additional, Galasso, Michele, additional, Daus, Franesca, additional, Giani, Valentina, additional, Gualini, Elena, additional, Garofani, Ilaria, additional, Riccio, Alfonso, additional, Biolcati, Marco, additional, Fabbri, Saverio, additional, Algeri, Michela, additional, Merlini, Piera, additional, Giannattasio, Cristina, additional, and Morelli, Marco, additional

Published
2024
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8. MULTIDRUG RESISTANT DYSLIPIDEMIA: A CASE REPORT

Author

Maloberti, Alessandro, primary, Daus, Francesca, additional, Pavanello, Chiara, additional, Toscani, Giorgio, additional, Riccio, Alfonso, additional, Fabbri, Saverio, additional, Ciampi, Claudio Mario, additional, Caccia, Andrea, additional, Tognola, Chiara, additional, Algeri, Michela, additional, Intravaia, Rita Cristina My, additional, Merlini, Piera, additional, Mosca, Lorena, additional, Cavallari, Ugo, additional, Giannattasio, Cristina, additional, and Morelli, Marco, additional

Published
2024
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9. CAROTID-FEMORAL PULSE WAVE VELOCITY PROGRESSION IN HYPERTENSIVE PATIENTS IS ASSOCIATED WITH SUBSEQUENT CV OUTCOMES

Author

Maloberti, Alessandro, primary, Rebora, Paola, additional, Occhino, Giuseppe, additional, Andreano, Anita, additional, Intravaia, Rita Cristina My, additional, Tognola, Chiara, additional, Toscani, Giorgio, additional, Morelli, Martina, additional, Pezzoli, Stefano, additional, D’Oro, Luca Cavalieri, additional, Russo, Antonio, additional, and Giannattasio, Cristina, additional

Published
2024
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10. HYPERTRIGLYCERIDEMIA IN PATIENTS WITH ACUTE AND CHRONIC CORONARY SYNDROME: PREVALENCE AND THEIR ASSOCIATION WITH EXTREME CARDIOVASCULAR RISK AND LEFT VENTRICULAR FUNCTION

Author

Maloberti, Alessandro, primary, Rosa, Antonio La, additional, Toscani, Giorgio, additional, Caccia, Andrea, additional, Gualini, Elena, additional, Pezzoli, Stefano, additional, Morelli, Martina, additional, Busti, Andrea, additional, Colombo, Valentina, additional, Tognola, Chiara, additional, Algeri, Michela, additional, Intravaia, Rita Cristina My, additional, Pirola, Roberto, additional, Giannattasio, Cristina, additional, and Garofani, Ilaria, additional

Published
2024
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11. Contemporary Advances in Cardiac Remote Monitoring: A Comprehensive, Updated Mini-Review

Author

Preda, A, Falco, R, Tognola, C, Carbonaro, M, Vargiu, S, Gallazzi, M, Baroni, M, Gigli, L, Varrenti, M, Colombo, G, Zanotto, G, Giannattasio, C, Mazzone, P, Guarracini, F, Preda, Alberto, Falco, Raffaele, Tognola, Chiara, Carbonaro, Marco, Vargiu, Sara, Gallazzi, Michela, Baroni, Matteo, Gigli, Lorenzo, Varrenti, Marisa, Colombo, Giulia, Zanotto, Gabriele, Giannattasio, Cristina, Mazzone, Patrizio, Guarracini, Fabrizio, Preda, A, Falco, R, Tognola, C, Carbonaro, M, Vargiu, S, Gallazzi, M, Baroni, M, Gigli, L, Varrenti, M, Colombo, G, Zanotto, G, Giannattasio, C, Mazzone, P, Guarracini, F, Preda, Alberto, Falco, Raffaele, Tognola, Chiara, Carbonaro, Marco, Vargiu, Sara, Gallazzi, Michela, Baroni, Matteo, Gigli, Lorenzo, Varrenti, Marisa, Colombo, Giulia, Zanotto, Gabriele, Giannattasio, Cristina, Mazzone, Patrizio, and Guarracini, Fabrizio

Abstract

Over the past decade, remote monitoring (RM) has become an increasingly popular way to improve healthcare and health outcomes. Modern cardiac implantable electronic devices (CIEDs) are capable of recording an increasing amount of data related to CIED function, arrhythmias, physiological status and hemodynamic parameters, providing in-depth and updated information on patient cardiovascular function. The extensive use of RM for patients with CIED allows for early diagnosis and rapid assessment of relevant issues, both clinical and technical, as well as replacing outpatient follow-up improving overall management without compromise safety. This approach is recommended by current guidelines for all eligible patients affected by different chronic cardiac conditions including either brady- and tachy-arrhythmias and heart failure. Beyond to clinical advantages, RM has demonstrated cost-effectiveness and is associated with elevated levels of patient satisfaction. Future perspectives include improving security, interoperability and diagnostic power as well as to engage patients with digital health technology. This review aims to update existing data concerning clinical outcomes in patients managed with RM in the wide spectrum of cardiac arrhythmias and Hear Failure (HF), disclosing also about safety, effectiveness, patient satisfaction and cost-saving.

Published
2024

12. Cardiovascular Structural and Functional Parameters in Idiopathic Pulmonary Fibrosis at Disease Diagnosis

Author

Faverio, P, Maloberti, A, Rebora, P, Intravaia, R, Tognola, C, Toscani, G, Amato, A, Leoni, V, Franco, G, Vitarelli, F, Spiti, S, Luppi, F, Valsecchi, M, Pesci, A, Giannattasio, C, Faverio, Paola, Maloberti, Alessandro, Rebora, Paola, Intravaia, Rita Cristina Myriam, Tognola, Chiara, Toscani, Giorgio, Amato, Anna, Leoni, Valerio, Franco, Giovanni, Vitarelli, Federica, Spiti, Simona, Luppi, Fabrizio, Valsecchi, Maria Grazia, Pesci, Alberto, Giannattasio, Cristina, Faverio, P, Maloberti, A, Rebora, P, Intravaia, R, Tognola, C, Toscani, G, Amato, A, Leoni, V, Franco, G, Vitarelli, F, Spiti, S, Luppi, F, Valsecchi, M, Pesci, A, Giannattasio, C, Faverio, Paola, Maloberti, Alessandro, Rebora, Paola, Intravaia, Rita Cristina Myriam, Tognola, Chiara, Toscani, Giorgio, Amato, Anna, Leoni, Valerio, Franco, Giovanni, Vitarelli, Federica, Spiti, Simona, Luppi, Fabrizio, Valsecchi, Maria Grazia, Pesci, Alberto, and Giannattasio, Cristina

Abstract

Introduction: Prevalence of cardiac and vascular fibrosis in patients with Idiopathic Pulmonary Fibrosis (IPF) has not been extensively evaluated. Aim: In this study, we aimed to evaluate the heart and vessels functional and structural properties in patients with IPF compared to healthy controls. An exploratory analysis regarding disease severity in IPF patients has been done. Methods: We enrolled 50 patients with IPF (at disease diagnosis before antifibrotic therapy initiation) and 50 controls matched for age and gender. Heart was evaluated through echocardiography and plasmatic NT-pro-brain natriuretic peptide that, together with patients’ symptoms, allow to define the presence of Heart Failure (HF) and diastolic dysfunction. Vessels were evaluated through Flow Mediated Dilation (FMD – endothelial function) and Pulse Wave Velocity (PWV—arterial stiffness) Results: Patients with IPF had a prevalence of diastolic disfunction of 83.8%, HF of 37.8% and vascular fibrosis of 76.6%. No statistically significant difference was observed in comparison to the control group who showed prevalence of diastolic disfunction, HF and vascular fibrosis of 67.3%, 24.5% and 84.8%, respectively. Disease severity seems not to affect PWV, FMD, diastolic dysfunction and HF. Conclusions: Patients with IPF early in the disease course do not present a significant CV fibrotic involvement when compared with age- and sex-matched controls. Bigger and adequately powered studies are needed to confirm our preliminary data and longitudinal studies are required in order to understand the time of appearance and progression rate of heart and vascular involvement in IPF subjects.

Published
2024

13. CAROTID-FEMORAL PULSE WAVE VELOCITY PROGRESSION IN HYPERTENSIVE PATIENTS IS ASSOCIATED WITH SUBSEQUENT CV OUTCOMES

Author

Maloberti, A, Rebora, P, Occhino, G, Andreano, A, Intravaia, R, Tognola, C, Toscani, G, Morelli, M, Pezzoli, S, D’Oro, L, Russo, A, Giannattasio, C, Maloberti, Alessandro, Rebora, Paola, Occhino, Giuseppe, Andreano, Anita, Intravaia, Rita Cristina My, Tognola, Chiara, Toscani, Giorgio, Morelli, Martina, Pezzoli, Stefano, D’Oro, Luca Cavalieri, Russo, Antonio, Giannattasio, Cristina, Maloberti, A, Rebora, P, Occhino, G, Andreano, A, Intravaia, R, Tognola, C, Toscani, G, Morelli, M, Pezzoli, S, D’Oro, L, Russo, A, Giannattasio, C, Maloberti, Alessandro, Rebora, Paola, Occhino, Giuseppe, Andreano, Anita, Intravaia, Rita Cristina My, Tognola, Chiara, Toscani, Giorgio, Morelli, Martina, Pezzoli, Stefano, D’Oro, Luca Cavalieri, Russo, Antonio, and Giannattasio, Cristina

Published
2024

14. EFFECT OF ANTI-PCSK9 ANTIBODIES ON ARTERY STRUCTURE AND FUNCTION: THE NIGUARDA HOSPITAL COHORT

Author

Maloberti, A, Toscani, G, Busti, A, Tognola, C, Intravaia, R, De Censi, L, Galasso, M, Daus, F, Giani, V, Gualini, E, Garofani, I, Riccio, A, Biolcati, M, Fabbri, S, Algeri, M, Merlini, P, Giannattasio, C, Morelli, M, Maloberti, Alessandro, Toscani, Giorgio, Busti, Andrea, Tognola, Chiara, Intravaia, Rita Cristina Mi, De Censi, Lorenzo, Galasso, Michele, Daus, Franesca, Giani, Valentina, Gualini, Elena, Garofani, Ilaria, Riccio, Alfonso, Biolcati, Marco, Fabbri, Saverio, Algeri, Michela, Merlini, Piera, Giannattasio, Cristina, Morelli, Martina, Maloberti, A, Toscani, G, Busti, A, Tognola, C, Intravaia, R, De Censi, L, Galasso, M, Daus, F, Giani, V, Gualini, E, Garofani, I, Riccio, A, Biolcati, M, Fabbri, S, Algeri, M, Merlini, P, Giannattasio, C, Morelli, M, Maloberti, Alessandro, Toscani, Giorgio, Busti, Andrea, Tognola, Chiara, Intravaia, Rita Cristina Mi, De Censi, Lorenzo, Galasso, Michele, Daus, Franesca, Giani, Valentina, Gualini, Elena, Garofani, Ilaria, Riccio, Alfonso, Biolcati, Marco, Fabbri, Saverio, Algeri, Michela, Merlini, Piera, Giannattasio, Cristina, and Morelli, Martina

Published
2024

15. HYPERTRIGLYCERIDEMIA IN PATIENTS WITH ACUTE AND CHRONIC CORONARY SYNDROME: PREVALENCE AND THEIR ASSOCIATION WITH EXTREME CARDIOVASCULAR RISK AND LEFT VENTRICULAR FUNCTION

Author

Maloberti, A, Rosa, A, Toscani, G, Caccia, A, Gualini, E, Pezzoli, S, Morelli, M, Busti, A, Colombo, V, Tognola, C, Algeri, M, Intravaia, R, Pirola, R, Giannattasio, C, Garofani, I, Maloberti, Alessandro, Rosa, Antonio La, Toscani, Giorgio, Caccia, Andrea, Gualini, Elena, Pezzoli, Stefano, Morelli, Martina, Busti, Andrea, Colombo, Valentina, Tognola, Chiara, Algeri, Michela, Intravaia, Rita Cristina My, Pirola, Roberto, Giannattasio, Cristina, Garofani, Ilaria, Maloberti, A, Rosa, A, Toscani, G, Caccia, A, Gualini, E, Pezzoli, S, Morelli, M, Busti, A, Colombo, V, Tognola, C, Algeri, M, Intravaia, R, Pirola, R, Giannattasio, C, Garofani, I, Maloberti, Alessandro, Rosa, Antonio La, Toscani, Giorgio, Caccia, Andrea, Gualini, Elena, Pezzoli, Stefano, Morelli, Martina, Busti, Andrea, Colombo, Valentina, Tognola, Chiara, Algeri, Michela, Intravaia, Rita Cristina My, Pirola, Roberto, Giannattasio, Cristina, and Garofani, Ilaria

Published
2024

17. Ultrasound-Assisted, Catheter-Directed Thrombolysis for Acute Intermediate/High-Risk Pulmonary Embolism: Design of the Multicenter USAT IH-PE Registry and Preliminary Results

Author

Colombo, Claudia, primary, Capsoni, Nicolò, additional, Russo, Filippo, additional, Iannaccone, Mario, additional, Adamo, Marianna, additional, Viola, Giovanna, additional, Bossi, Ilaria Emanuela, additional, Villanova, Luca, additional, Tognola, Chiara, additional, Curci, Camilla, additional, Morelli, Francesco, additional, Guerrieri, Rossella, additional, Occhi, Lucia, additional, Chizzola, Giuliano, additional, Rampoldi, Antonio, additional, Musca, Francesco, additional, De Nittis, Giuseppe, additional, Galli, Mario, additional, Boccuzzi, Giacomo, additional, Savio, Daniele, additional, Bernasconi, Davide, additional, D’Angelo, Luciana, additional, Garascia, Andrea, additional, Chieffo, Alaide, additional, Montorfano, Matteo, additional, Oliva, Fabrizio, additional, and Sacco, Alice, additional

Published
2024
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19. Ultrasound-Assisted, Catheter-Directed Thrombolysis for Acute Intermediate/High Risk Pulmonary Embolism: Design of the Multicenter USAT IH-PE Registry and Preliminary Results

Author

Colombo, Claudia, primary, Capsoni, Nicolò, additional, Russo, Filippo, additional, Iannaccone, Mario, additional, Adamo, Marianna, additional, Viola, Giovanna, additional, Bossi, Ilaria Emanuela, additional, Villanova, Luca, additional, Tognola, Chiara, additional, Curci, Camilla, additional, Morelli, Francesco, additional, Guerrieri, Rossella, additional, Occhi, Lucia, additional, Chizzola, Giuliano, additional, Rampoldi, Antonio, additional, Musca, Francesco, additional, De Nittis, Giuseppe, additional, Galli, Mario, additional, Boccuzzi, Giacomo, additional, Savio, Daniele, additional, Bernasconi, Davide, additional, D’Angelo, Luciana, additional, Garascia, Andrea, additional, Chieffo, Alaide, additional, Montorfano, Matteo, additional, Oliva, Fabrizio, additional, and Sacco, Alice, additional

Published
2023
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20. Contemporary Advances in Cardiac Remote Monitoring: A Comprehensive, Updated Mini-Review.

Author

Preda, Alberto, Falco, Raffaele, Tognola, Chiara, Carbonaro, Marco, Vargiu, Sara, Gallazzi, Michela, Baroni, Matteo, Gigli, Lorenzo, Varrenti, Marisa, Colombo, Giulia, Zanotto, Gabriele, Giannattasio, Cristina, Mazzone, Patrizio, and Guarracini, Fabrizio

Subjects
PATIENT satisfaction, ARRHYTHMIA, DIGITAL health, ARTIFICIAL implants, HEART failure
Abstract

Over the past decade, remote monitoring (RM) has become an increasingly popular way to improve healthcare and health outcomes. Modern cardiac implantable electronic devices (CIEDs) are capable of recording an increasing amount of data related to CIED function, arrhythmias, physiological status and hemodynamic parameters, providing in-depth and updated information on patient cardiovascular function. The extensive use of RM for patients with CIED allows for early diagnosis and rapid assessment of relevant issues, both clinical and technical, as well as replacing outpatient follow-up improving overall management without compromise safety. This approach is recommended by current guidelines for all eligible patients affected by different chronic cardiac conditions including either brady- and tachy-arrhythmias and heart failure. Beyond to clinical advantages, RM has demonstrated cost-effectiveness and is associated with elevated levels of patient satisfaction. Future perspectives include improving security, interoperability and diagnostic power as well as to engage patients with digital health technology. This review aims to update existing data concerning clinical outcomes in patients managed with RM in the wide spectrum of cardiac arrhythmias and Hear Failure (HF), disclosing also about safety, effectiveness, patient satisfaction and cost-saving. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Metabolic syndrome is related to vascular structural alterations but not to functional ones both in hypertensives and healthy subjects

Author

Maloberti, Alessandro, primary, Bombelli, Michele, additional, Vallerio, Paola, additional, Milani, Martina, additional, Cartella, Iside, additional, Tavecchia, Giovanni, additional, Tognola, Chiara, additional, Grasso, Enzo, additional, Sun, Jinwei, additional, De Chiara, Benedetta, additional, Riccobono, Salvatore, additional, Grassi, Guido, additional, and Giannattasio, Cristina, additional

Published
2021
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23. Hyperuricemia prevalence in healthy subjects and its relationship with cardiovascular target organ damage

Author

Maloberti, Alessandro, primary, Qualliu, Esmerilda, additional, Occhi, Lucia, additional, Sun, Jinwei, additional, Grasso, Enzo, additional, Tognola, Chiara, additional, Tavecchia, Giovanni, additional, Cartella, Iside, additional, Milani, Martina, additional, Vallerio, Paola, additional, Signorini, Stefano, additional, Brambilla, Paolo, additional, Casati, Marco, additional, Bombelli, Michele, additional, Grassi, Guido, additional, and Giannattasio, Cristina, additional

Published
2021
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25. [Contemporary diagnosis and treatment of tricuspid regurgitation: from neglected valve to primetime].

Author

Montalto C, Tognola C, Ghidini S, Monticelli M, Nava S, Soriano F, Munafò AR, Tavoletta P, Bruschi G, Esposito G, Mangieri A, Giannattasio C, De Marco F, Oliva F, and Oreglia JA

Subjects
Humans, Practice Guidelines as Topic, Quality of Life, Tricuspid Valve surgery, Heart Valve Prosthesis Implantation methods, Tricuspid Valve Insufficiency therapy, Tricuspid Valve Insufficiency diagnosis, Tricuspid Valve Insufficiency surgery, Tricuspid Valve Insufficiency physiopathology
Abstract

Tricuspid insufficiency has long been considered an entity with low prognostic importance and associated with symptoms and signs only secondarily to left heart pathology. Scientific research in recent years has debunked this myth, demonstrating a key role in determining symptoms and signs of right heart failure, even in advanced stages. In parallel, advances in transcatheter technologies have opened up treatment options even for patients with increased surgical risk, who were previously excluded from traditional surgical options, with increasingly convincing results in reducing symptoms and improving the quality of life of our patients. The contemporary challenge is to translate these messages into everyday clinical practice and to encourage the centralization of patients in centers that currently have the expertise for feasibility evaluation and subsequent treatment. In this Review, we will analyze the most recent evidence on the pathophysiology and diagnosis of tricuspid insufficiency, the latest recommendations from European guidelines, and we will try to illustrate the most common technologies for percutaneous treatment and the abundant evidence supporting them.

Published
2024
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