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1. Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019

Author: Kyu, H, Vongpradith, A, Sirota, S, Novotney, A, Troeger, C, Doxey, M, Bender, R, Ledesma, J, Biehl, M, Albertson, S, Frostad, J, Burkart, K, Bennitt, F, Zhao, J, Gardner, W, Hagins, H, Bryazka, D, Dominguez, R, Abate, S, Abdelmasseh, M, Abdoli, A, Abdoli, G, Abedi, A, Abedi, V, Abegaz, T, Abidi, H, Aboagye, R, Abolhassani, H, Abtew, Y, Abubaker Ali, H, Abu-Gharbieh, E, Abu-Zaid, A, Adamu, K, Addo, I, Adegboye, O, Adnan, M, Adnani, Q, Afzal, M, Afzal, S, Ahinkorah, B, Ahmad, A, Ahmad, S, Ahmadi, A, Ahmadi, S, Ahmed, H, Ahmed, J, Ahmed Rashid, T, Akbarzadeh-Khiavi, M, Al Hamad, H, Albano, L, Aldeyab, M, Alemu, B, Alene, K, Algammal, A, Alhalaiqa, F, Alhassan, R, Ali, B, Ali, L, Ali, M, Ali, S, Alimohamadi, Y, Alipour, V, Al-Jumaily, A, Aljunid, S, Almustanyir, S, Al-Raddadi, R, Al-Rifai, R, Alryalat, S, Alvis-Guzman, N, Alvis-Zakzuk, N, Ameyaw, E, Aminian Dehkordi, J, Amuasi, J, Amugsi, D, Anbesu, E, Ansar, A, Anyasodor, A, Arabloo, J, Areda, D, Argaw, A, Argaw, Z, Arulappan, J, Aruleba, R, Asemahagn, M, Athari, S, Atlaw, D, Attia, E, Attia, S, Aujayeb, A, Awoke, T, Ayana, T, Ayanore, M, Azadnajafabad, S, Azangou-Khyavy, M, Azari, S, Azari Jafari, A, Badar, M, Badiye, A, Baghcheghi, N, Bagherieh, S, Baig, A, Banach, M, Banerjee, I, Bardhan, M, Barone-Adesi, F, Barqawi, H, Barrow, A, Bashiri, A, Bassat, Q, Batiha, A, Belachew, A, Belete, M, Belgaumi, U, Bhagavathula, A, Bhardwaj, N, Bhardwaj, P, Bhatt, P, Bhojaraja, V, Bhutta, Z, Bhuyan, S, Bijani, A, Bitaraf, S, Bodicha, B, Briko, N, Buonsenso, D, Butt, M, Cai, J, Camargos, P, Camera, L, Chakraborty, P, Chanie, M, Charan, J, Chattu, V, Ching, P, Choi, S, Chong, Y, Choudhari, S, Chowdhury, E, Christopher, D, Chu, D, Cobb, N, Cohen, A, Cruz-Martins, N, Dadras, O, Dagnaw, F, Dai, X, Dandona, L, Dandona, R, Dao, A, Debela, S, Demisse, B, Demisse, F, Demissie, S, Dereje, D, Desai, H, Desta, A, Desye, B, Dhingra, S, Diao, N, Diaz, D, Digesa, L, Doan, L, Dodangeh, M, Dongarwar, D, Dorostkar, F, dos Santos, W, Dsouza, H, Dubljanin, E, Durojaiye, O, Edinur, H, Ehsani-Chimeh, E, Eini, E, Ekholuenetale, M, Ekundayo, T, El Desouky, E, El Sayed, I, El Sayed Zaki, M, Elhadi, M, Elkhapery, A, Emami, A, Engelbert Bain, L, Erkhembayar, R, Etaee, F, Ezati Asar, M, Fagbamigbe, A, Falahi, S, Fallahzadeh, A, Faraj, A, Faraon, E, Fatehizadeh, A, Ferrara, P, Ferrari, A, Fetensa, G, Fischer, F, Flavel, J, Foroutan, M, Gaal, P, Gaidhane, A, Gaihre, S, Galehdar, N, Garcia-Basteiro, A, Garg, T, Gebrehiwot, M, Gebremichael, M, Gela, Y, Gemeda, B, Gessner, B, Getachew, M, Getie, A, Ghamari, S, Ghasemi Nour, M, Ghashghaee, A, Gholamrezanezhad, A, Gholizadeh, A, Ghosh, R, Ghozy, S, Goleij, P, Golitaleb, M, Gorini, G, Goulart, A, Goyomsa, G, Guadie, H, Gudisa, Z, Guled, R, Gupta, S, Gupta, V, Guta, A, Habibzadeh, P, Haj-Mirzaian, A, Halwani, R, Hamidi, S, Hannan, M, Harorani, M, Hasaballah, A, Hasani, H, Hassan, A, Hassani, S, Hassanian-Moghaddam, H, Hassankhani, H, Hayat, K, Heibati, B, Heidari, M, Heyi, D, Hezam, K, Holla, R, Hong, S, Horita, N, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Househ, M, Hoveidamanesh, S, Huang, J, Hussein, N, Iavicoli, I, Ibitoye, S, Ikuta, K, Ilesanmi, O, Ilic, I, Ilic, M, Immurana, M, Ismail, N, Iwagami, M, Jaafari, J, Jamshidi, E, Jang, S, Javadi Mamaghani, A, Javaheri, T, Javanmardi, F, Javidnia, J, Jayapal, S, Jayarajah, U, Jayaram, S, Jema, A, Jeong, W, Jonas, J, Joseph, N, Joukar, F, Jozwiak, J, K, V, Kabir, Z, Kacimi, S, Kadashetti, V, Kalankesh, L, Kalhor, R, Kamath, A, Kamble, B, Kandel, H, Kanko, T, Karaye, I, Karch, A, Karkhah, S, Kassa, B, Katoto, P, Kaur, H, Kaur, R, Keikavoosi-Arani, L, Keykhaei, M, Khader, Y, Khajuria, H, Khan, E, Khan, G, Khan, I, Khan, M, Khan, Y, Khatatbeh, M, Khosravifar, M, Khubchandani, J, Kim, M, Kimokoti, R, Kisa, A, Kisa, S, Kissoon, N, Knibbs, L, Kochhar, S, Kompani, F, Koohestani, H, Korshunov, V, Kosen, S, Koul, P, Koyanagi, A, Krishan, K, Kuate Defo, B, Kumar, G, Kurmi, O, Kuttikkattu, A, Lal, D, Lam, J, Landires, I, Ledda, C, Lee, S, Levi, M, Lewycka, S, Liu, G, Liu, W, Lodha, R, Lorenzovici, L, Lotfi, M, Loureiro, J, Madadizadeh, F, Mahmoodpoor, A, Mahmoudi, R, Mahmoudimanesh, M, Majidpoor, J, Makki, A, Malakan Rad, E, Malik, A, Mallhi, T, Manla, Y, Matei, C, Mathioudakis, A, Maude, R, Mehrabi Nasab, E, Melese, A, Memish, Z, Mendoza-Cano, O, Mentis, A, Meretoja, T, Merid, M, Mestrovic, T, Micheletti Gomide Nogueira de Sa, A, Mijena, G, Minh, L, Mir, S, Mirfakhraie, R, Mirmoeeni, S, Mirza, A, Mirza, M, Mirza-Aghazadeh-Attari, M, Misganaw, A, Mohammadi, E, Mohammadi, M, Mohammed, A, Mohammed, S, Mohan, S, Mohseni, M, Moka, N, Mokdad, A, Momtazmanesh, S, Monasta, L, Moniruzzaman, M, Montazeri, F, Moore, C, Moradi, A, Morawska, L, Mosser, J, Mostafavi, E, Motaghinejad, M, Mousavi Isfahani, H, Mousavi-Aghdas, S, Mubarik, S, Murillo-Zamora, E, Mustafa, G, Nair, S, Nair, T, Najafi, H, Naqvi, A, Narasimha Swamy, S, Natto, Z, Nayak, B, Nejadghaderi, S, Nguyen, H, Niazi, R, Nogueira de Sa, A, Nouraei, H, Nowroozi, A, Nunez-Samudio, V, Nzoputam, C, Nzoputam, O, Oancea, B, Ochir, C, Odukoya, O, Okati-Aliabad, H, Okekunle, A, Okonji, O, Olagunju, A, Olufadewa, I, Omar Bali, A, Omer, E, Oren, E, Ota, E, Otstavnov, N, Oulhaj, A, P A, M, Padubidri, J, Pakshir, K, Pakzad, R, Palicz, T, Pandey, A, Pant, S, Pardhan, S, Park, E, Pashazadeh Kan, F, Paudel, R, Pawar, S, Peng, M, Pereira, G, Perna, S, Perumalsamy, N, Petcu, I, Pigott, D, Piracha, Z, Podder, V, Polibin, R, Postma, M, Pourasghari, H, Pourtaheri, N, Qadir, M, Raad, M, Rabiee, M, Rabiee, N, Raeghi, S, Rafiei, A, Rahim, F, Rahimi, M, Rahimi-Movaghar, V, Rahman, A, Rahman, M, Rahmani, A, Rahmanian, V, Ram, P, Ramezanzadeh, K, Rana, J, Ranasinghe, P, Rani, U, Rao, S, Rashedi, S, Rashidi, M, Rasul, A, Ratan, Z, Rawaf, D, Rawaf, S, Rawassizadeh, R, Razeghinia, M, Redwan, E, Reitsma, M, Renzaho, A, Rezaeian, M, Riad, A, Rikhtegar, R, Rodriguez, J, Rogowski, E, Ronfani, L, Rudd, K, Saddik, B, Sadeghi, E, Saeed, U, Safary, A, Safi, S, Sahebazzamani, M, Sahebkar, A, Sakhamuri, S, Salehi, S, Salman, M, Samadi Kafil, H, Samy, A, Santric-Milicevic, M, Sao Jose, B, Sarkhosh, M, Sathian, B, Sawhney, M, Saya, G, Seidu, A, Seylani, A, Shaheen, A, Shaikh, M, Shaker, E, Shamshad, H, Sharew, M, Sharhani, A, Sharifi, A, Sharma, P, Sheidaei, A, Shenoy, S, Shetty, J, Shiferaw, D, Shigematsu, M, Shin, J, Shirzad-Aski, H, Shivakumar, K, Shivalli, S, Shobeiri, P, Simegn, W, Simpson, C, Singh, H, Singh, J, Singh, P, Siwal, S, Skryabin, V, Skryabina, A, Soltani-Zangbar, M, Song, S, Song, Y, Sood, P, Sreeramareddy, C, Steiropoulos, P, Suleman, M, Tabatabaeizadeh, S, Tahamtan, A, Taheri, M, Taheri Soodejani, M, Taki, E, Talaat, I, Tampa, M, Tandukar, S, Tat, N, Tat, V, Tefera, Y, Temesgen, G, Temsah, M, Tesfaye, A, Tesfaye, D, Tessema, B, Thapar, R, Ticoalu, J, Tiyuri, A, Tleyjeh, I, Togtmol, M, Tovani-Palone, M, Tufa, D, Ullah, I, Upadhyay, E, Valadan Tahbaz, S, Valdez, P, Valizadeh, R, Vardavas, C, Vasankari, T, Vo, B, Vu, L, Wagaye, B, Waheed, Y, Wang, Y, Waris, A, West, T, Wickramasinghe, N, Xu, X, Yaghoubi, S, Yahya, G, Yahyazadeh Jabbari, S, Yon, D, Yonemoto, N, Zaman, B, Zandifar, A, Zangiabadian, M, Zar, H, Zare, I, Zareshahrabadi, Z, Zarrintan, A, Zastrozhin, M, Zeng, W, Zhang, M, Zhang, Z, Zhong, C, Zoladl, M, Zumla, A, Lim, S, Vos, T, Naghavi, M, Brauer, M, Hay, S, Murray, C, Kyu H. H., Vongpradith A., Sirota S. B., Novotney A., Troeger C. E., Doxey M. C., Bender R. G., Ledesma J. R., Biehl M. H., Albertson S. B., Frostad J. J., Burkart K., Bennitt F. B., Zhao J. T., Gardner W. M., Hagins H., Bryazka D., Dominguez R. -M. V., Abate S. M., Abdelmasseh M., Abdoli A., Abdoli G., Abedi A., Abedi V., Abegaz T. M., Abidi H., Aboagye R. G., Abolhassani H., Abtew Y. D., Abubaker Ali H., Abu-Gharbieh E., Abu-Zaid A., Adamu K., Addo I. Y., Adegboye O. A., Adnan M., Adnani Q. E. S., Afzal M. S., Afzal S., Ahinkorah B. O., Ahmad A., Ahmad A. R., Ahmad S., Ahmadi A., Ahmadi S., Ahmed H., Ahmed J. Q., Ahmed Rashid T., Akbarzadeh-Khiavi M., Al Hamad H., Albano L., Aldeyab M. A., Alemu B. M., Alene K. A., Algammal A. M., Alhalaiqa F. A. N., Alhassan R. K., Ali B. A., Ali L., Ali M. M., Ali S. S., Alimohamadi Y., Alipour V., Al-Jumaily A., Aljunid S. M., Almustanyir S., Al-Raddadi R. M., Al-Rifai R. H. H., AlRyalat S. A. S., Alvis-Guzman N., Alvis-Zakzuk N. J., Ameyaw E. K., Aminian Dehkordi J. J., Amuasi J. H., Amugsi D. A., Anbesu E. W., Ansar A., Anyasodor A. E., Arabloo J., Areda D., Argaw A. M., Argaw Z. G., Arulappan J., Aruleba R. T., Asemahagn M. A., Athari S. S., Atlaw D., Attia E. F., Attia S., Aujayeb A., Awoke T., Ayana T. M., Ayanore M. A., Azadnajafabad S., Azangou-Khyavy M., Azari S., Azari Jafari A., Badar M., Badiye A. D., Baghcheghi N., Bagherieh S., Baig A. A., Banach M., Banerjee I., Bardhan M., Barone-Adesi F., Barqawi H. J., Barrow A., Bashiri A., Bassat Q., Batiha A. -M. M., Belachew A. B., Belete M. A., Belgaumi U. I., Bhagavathula A. S., Bhardwaj N., Bhardwaj P., Bhatt P., Bhojaraja V. S., Bhutta Z. A., Bhuyan S. S., Bijani A., Bitaraf S., Bodicha B. B. A., Briko N. I., Buonsenso D., Butt M. H., Cai J., Camargos P., Camera L. A., Chakraborty P. A., Chanie M. G., Charan J., Chattu V. K., Ching P. R., Choi S., Chong Y. Y., Choudhari S. G., Chowdhury E. K., Christopher D. J., Chu D. -T., Cobb N. L., Cohen A. J., Cruz-Martins N., Dadras O., Dagnaw F. T., Dai X., Dandona L., Dandona R., Dao A. T. M., Debela S. A., Demisse B., Demisse F. W., Demissie S., Dereje D., Desai H. D., Desta A. A., Desye B., Dhingra S., Diao N., Diaz D., Digesa L. E., Doan L. P., Dodangeh M., Dongarwar D., Dorostkar F., dos Santos W. M., Dsouza H. L., Dubljanin E., Durojaiye O. C., Edinur H. A., Ehsani-Chimeh E., Eini E., Ekholuenetale M., Ekundayo T. C., El Desouky E. D., El Sayed I., El Sayed Zaki M., Elhadi M., Elkhapery A. M. R., Emami A., Engelbert Bain L., Erkhembayar R., Etaee F., Ezati Asar M., Fagbamigbe A. F., Falahi S., Fallahzadeh A., Faraj A., Faraon E. J. A., Fatehizadeh A., Ferrara P., Ferrari A. A., Fetensa G., Fischer F., Flavel J., Foroutan M., Gaal P. A., Gaidhane A. M., Gaihre S., Galehdar N., Garcia-Basteiro A. L., Garg T., Gebrehiwot M. D., Gebremichael M. A., Gela Y. Y., Gemeda B. N. B., Gessner B. D., Getachew M., Getie A., Ghamari S. -H., Ghasemi Nour M., Ghashghaee A., Gholamrezanezhad A., Gholizadeh A., Ghosh R., Ghozy S., Goleij P., Golitaleb M., Gorini G., Goulart A. C., Goyomsa G. G., Guadie H. A., Gudisa Z., Guled R. A., Gupta S., Gupta V. B., Gupta V. K., Guta A., Habibzadeh P., Haj-Mirzaian A., Halwani R., Hamidi S., Hannan M. A., Harorani M., Hasaballah A. I., Hasani H., Hassan A. M., Hassani S., Hassanian-Moghaddam H., Hassankhani H., Hayat K., Heibati B., Heidari M., Heyi D. Z., Hezam K., Holla R., Hong S. H., Horita N., Hosseini M. -S., Hosseinzadeh M., Hostiuc M., Househ M., Hoveidamanesh S., Huang J., Hussein N. R., Iavicoli I., Ibitoye S. E., Ikuta K. S., Ilesanmi O. S., Ilic I. M., Ilic M. D., Immurana M., Ismail N. E., Iwagami M., Jaafari J., Jamshidi E., Jang S. -I., Javadi Mamaghani A., Javaheri T., Javanmardi F., Javidnia J., Jayapal S. K., Jayarajah U., Jayaram S., Jema A. T., Jeong W., Jonas J. B., Joseph N., Joukar F., Jozwiak J. J., K V., Kabir Z., Kacimi S. E. O., Kadashetti V., Kalankesh L. R., Kalhor R., Kamath A., Kamble B. D., Kandel H., Kanko T. K., Karaye I. M., Karch A., Karkhah S., Kassa B. G., Katoto P. D., Kaur H., Kaur R. J., Keikavoosi-Arani L., Keykhaei M., Khader Y. S., Khajuria H., Khan E. A., Khan G., Khan I. A., Khan M., Khan M. N., Khan M. A., Khan Y. H., Khatatbeh M. M., Khosravifar M., Khubchandani J., Kim M. S., Kimokoti R. W., Kisa A., Kisa S., Kissoon N., Knibbs L. D., Kochhar S., Kompani F., Koohestani H. R., Korshunov V. A., Kosen S., Koul P. A., Koyanagi A., Krishan K., Kuate Defo B., Kumar G. A., Kurmi O. P., Kuttikkattu A., Lal D. K., Lam J., Landires I., Ledda C., Lee S. -W., Levi M., Lewycka S., Liu G., Liu W., Lodha R., Lorenzovici L., Lotfi M., Loureiro J. A., Madadizadeh F., Mahmoodpoor A., Mahmoudi R., Mahmoudimanesh M., Majidpoor J., Makki A., Malakan Rad E., Malik A. A., Mallhi T. H., Manla Y., Matei C. N., Mathioudakis A. G., Maude R. J., Mehrabi Nasab E., Melese A., Memish Z. A., Mendoza-Cano O., Mentis A. -F. A., Meretoja T. J., Merid M. W., Mestrovic T., Micheletti Gomide Nogueira de Sa A. C., Mijena G. F. W., Minh L. H. N., Mir S. A., Mirfakhraie R., Mirmoeeni S., Mirza A. Z., Mirza M., Mirza-Aghazadeh-Attari M., Misganaw A. S., Misganaw A. T., Mohammadi E., Mohammadi M., Mohammed A., Mohammed S., Mohan S., Mohseni M., Moka N., Mokdad A. H., Momtazmanesh S., Monasta L., Moniruzzaman M., Montazeri F., Moore C. E., Moradi A., Morawska L., Mosser J. F., Mostafavi E., Motaghinejad M., Mousavi Isfahani H., Mousavi-Aghdas S. A., Mubarik S., Murillo-Zamora E., Mustafa G., Nair S., Nair T. S., Najafi H., Naqvi A. A., Narasimha Swamy S., Natto Z. S., Nayak B. P., Nejadghaderi S. A., Nguyen H. V. N., Niazi R. K., Nogueira de Sa A. T., Nouraei H., Nowroozi A., Nunez-Samudio V., Nzoputam C. I., Nzoputam O. J., Oancea B., Ochir C., Odukoya O. O., Okati-Aliabad H., Okekunle A. P., Okonji O. C., Olagunju A. T., Olufadewa I. I., Omar Bali A., Omer E., Oren E., Ota E., Otstavnov N., Oulhaj A., P A M., Padubidri J. R., Pakshir K., Pakzad R., Palicz T., Pandey A., Pant S., Pardhan S., Park E. -C., Park E. -K., Pashazadeh Kan F., Paudel R., Pawar S., Peng M., Pereira G., Perna S., Perumalsamy N., Petcu I. -R., Pigott D. M., Piracha Z. Z., Podder V., Polibin R. V., Postma M. J., Pourasghari H., Pourtaheri N., Qadir M. M. F., Raad M., Rabiee M., Rabiee N., Raeghi S., Rafiei A., Rahim F., Rahimi M., Rahimi-Movaghar V., Rahman A., Rahman M. O., Rahman M., Rahman M. A., Rahmani A. M., Rahmanian V., Ram P., Ramezanzadeh K., Rana J., Ranasinghe P., Rani U., Rao S. J., Rashedi S., Rashidi M. -M., Rasul A., Ratan Z. A., Rawaf D. L., Rawaf S., Rawassizadeh R., Razeghinia M. S., Redwan E. M. M., Reitsma M. B., Renzaho A. M. N., Rezaeian M., Riad A., Rikhtegar R., Rodriguez J. A. B., Rogowski E. L. B., Ronfani L., Rudd K. E., Saddik B., Sadeghi E., Saeed U., Safary A., Safi S. Z., Sahebazzamani M., Sahebkar A., Sakhamuri S., Salehi S., Salman M., Samadi Kafil H., Samy A. M., Santric-Milicevic M. M., Sao Jose B. P., Sarkhosh M., Sathian B., Sawhney M., Saya G. K., Seidu A. -A., Seylani A., Shaheen A. A., Shaikh M. A., Shaker E., Shamshad H., Sharew M. M., Sharhani A., Sharifi A., Sharma P., Sheidaei A., Shenoy S. M., Shetty J. K., Shiferaw D. S., Shigematsu M., Shin J. I., Shirzad-Aski H., Shivakumar K. M., Shivalli S., Shobeiri P., Simegn W., Simpson C. R., Singh H., Singh J. A., Singh P., Siwal S. S., Skryabin V. Y., Skryabina A. A., Soltani-Zangbar M. S., Song S., Song Y., Sood P., Sreeramareddy C. T., Steiropoulos P., Suleman M., Tabatabaeizadeh S. -A., Tahamtan A., Taheri M., Taheri Soodejani M., Taki E., Talaat I. M., Tampa M., Tandukar S., Tat N. Y., Tat V. Y., Tefera Y. M., Temesgen G., Temsah M. -H., Tesfaye A., Tesfaye D. G., Tessema B., Thapar R., Ticoalu J. H. V., Tiyuri A., Tleyjeh I. I., Togtmol M., Tovani-Palone M. R., Tufa D. G., Ullah I., Upadhyay E., Valadan Tahbaz S., Valdez P. R., Valizadeh R., Vardavas C., Vasankari T. J., Vo B., Vu L. G., Wagaye B., Waheed Y., Wang Y., Waris A., West T. E., Wickramasinghe N. D., Xu X., Yaghoubi S., Yahya G. A. T., Yahyazadeh Jabbari S. H., Yon D. K., Yonemoto N., Zaman B. A., Zandifar A., Zangiabadian M., Zar H. J., Zare I., Zareshahrabadi Z., Zarrintan A., Zastrozhin M. S., Zeng W., Zhang M., Zhang Z. -J., Zhong C., Zoladl M., Zumla A., Lim S. S., Vos T., Naghavi M., Brauer M., Hay S. I., Murray C. J. L., Kyu, H, Vongpradith, A, Sirota, S, Novotney, A, Troeger, C, Doxey, M, Bender, R, Ledesma, J, Biehl, M, Albertson, S, Frostad, J, Burkart, K, Bennitt, F, Zhao, J, Gardner, W, Hagins, H, Bryazka, D, Dominguez, R, Abate, S, Abdelmasseh, M, Abdoli, A, Abdoli, G, Abedi, A, Abedi, V, Abegaz, T, Abidi, H, Aboagye, R, Abolhassani, H, Abtew, Y, Abubaker Ali, H, Abu-Gharbieh, E, Abu-Zaid, A, Adamu, K, Addo, I, Adegboye, O, Adnan, M, Adnani, Q, Afzal, M, Afzal, S, Ahinkorah, B, Ahmad, A, Ahmad, S, Ahmadi, A, Ahmadi, S, Ahmed, H, Ahmed, J, Ahmed Rashid, T, Akbarzadeh-Khiavi, M, Al Hamad, H, Albano, L, Aldeyab, M, Alemu, B, Alene, K, Algammal, A, Alhalaiqa, F, Alhassan, R, Ali, B, Ali, L, Ali, M, Ali, S, Alimohamadi, Y, Alipour, V, Al-Jumaily, A, Aljunid, S, Almustanyir, S, Al-Raddadi, R, Al-Rifai, R, Alryalat, S, Alvis-Guzman, N, Alvis-Zakzuk, N, Ameyaw, E, Aminian Dehkordi, J, Amuasi, J, Amugsi, D, Anbesu, E, Ansar, A, Anyasodor, A, Arabloo, J, Areda, D, Argaw, A, Argaw, Z, Arulappan, J, 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G., Ullah I., Upadhyay E., Valadan Tahbaz S., Valdez P. R., Valizadeh R., Vardavas C., Vasankari T. J., Vo B., Vu L. G., Wagaye B., Waheed Y., Wang Y., Waris A., West T. E., Wickramasinghe N. D., Xu X., Yaghoubi S., Yahya G. A. T., Yahyazadeh Jabbari S. H., Yon D. K., Yonemoto N., Zaman B. A., Zandifar A., Zangiabadian M., Zar H. J., Zare I., Zareshahrabadi Z., Zarrintan A., Zastrozhin M. S., Zeng W., Zhang M., Zhang Z. -J., Zhong C., Zoladl M., Zumla A., Lim S. S., Vos T., Naghavi M., Brauer M., Hay S. I., and Murray C. J. L.
Abstract: Background: The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years and adults has not been studied as comprehensively as it has been in children younger than 5 years. We assessed the burden and trends of LRIs and risk factors across all age groups by sex, for 204 countries and territories. Methods: In this analysis of data for the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we used clinician-diagnosed pneumonia or bronchiolitis as our case definition for LRIs. We included International Classification of Diseases 9th edition codes 079.6, 466–469, 470.0, 480–482.8, 483.0–483.9, 484.1–484.2, 484.6–484.7, and 487–489 and International Classification of Diseases 10th edition codes A48.1, A70, B97.4–B97.6, J09–J15.8, J16–J16.9, J20–J21.9, J91.0, P23.0–P23.4, and U04–U04.9. We used the Cause of Death Ensemble modelling strategy to analyse 23 109 site-years of vital registration data, 825 site-years of sample vital registration data, 1766 site-years of verbal autopsy data, and 681 site-years of mortality surveillance data. We used DisMod-MR 2.1, a Bayesian meta-regression tool, to analyse age–sex-specific incidence and prevalence data identified via systematic reviews of the literature, population-based survey data, and claims and inpatient data. Additionally, we estimated age–sex-specific LRI mortality that is attributable to the independent effects of 14 risk factors. Findings: Globally, in 2019, we estimated that there were 257 million (95% uncertainty interval [UI] 240–275) LRI incident episodes in males and 232 million (217–248) in females. In the same year, LRIs accounted for 1·30 million (95% UI 1·18–1·42) male deaths and 1·20 million (1·07–1·33) female deaths. Age-standardised incidence and mortality rates were 1·17 times (95% UI 1·16–1·18) and 1·31 times (95% UI 1·23–1·41) greater in males than in females in 2019. Between 1990 and 2019, LRI incidence and mortality rates decl
Published: 2022

2. Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019

Author: Peden, AE, Cullen, P, Francis, KL, Moeller, H, Peden, MM, Ye, P, Tian, M, Zou, Z, Sawyer, SM, Aali, A, Abbasi-Kangevari, Z, Abbasi-Kangevari, M, Abdelmasseh, M, Abdoun, M, Abd-Rabu, R, Abdulah, DM, Abdurehman, AM, Abebe, G, Abebe, AM, Abedi, A, Abidi, H, Aboagye, RG, Ali, HA, Abu-Gharbieh, E, Adane, DE, Adane, TD, Addo, IY, Adewole, OG, Adhikari, S, Adnan, M, Adnani, QES, Afolabi, AAB, Afzal, S, Afzal, MS, Aghdam, ZB, Ahinkorah, BO, Ahmad, AR, Ahmad, T, Ahmad, S, Ahmadi, A, Ahmed, H, Ahmed, MB, Ahmed, A, Ahmed, JQ, Rashid, TA, Aithala, JP, Aji, B, Akhlaghdoust, M, Alahdab, F, Alanezi, FM, Alemayehu, A, Al Hamad, H, Ali, SS, Ali, L, Alimohamadi, Y, Alipour, V, Aljunid, SM, Almidani, L, Almustanyir, S, Altirkawi, KA, Alvis-Zakzuk, NJ, Ameyaw, EK, Amin, TT, Amir-Behghadami, M, Amiri, S, Amiri, H, Anagaw, TF, Andrei, T, Andrei, CL, Anvari, D, Anwar, SL, Anyasodor, AE, Arabloo, J, Arab-Zozani, M, Arja, A, Arulappan, J, Arumugam, A, Aryannejad, A, Asgary, S, Ashraf, T, Athari, SS, Atreya, A, Attia, S, Aujayeb, A, Awedew, AF, Azadnajafabad, S, Azangou-Khyavy, M, Azari, S, Jafari, AA, Azizi, H, Azzam, AY, Badiye, AD, Baghcheghi, N, Bagherieh, S, Baig, AA, Bakkannavar, SM, Balta, AB, Banach, M, Banik, PC, Bansal, H, Bardhan, M, Barone-Adesi, F, Barrow, A, Bashiri, A, Baskaran, P, Basu, S, Bayileyegn, NS, Bekel, AA, Bekele, AB, Bendak, S, Bensenor, IM, Berhie, AY, Bhagat, DS, Bhagavathula, AS, Bhardwaj, P, Bhardwaj, N, Bhaskar, S, Bhat, AN, Bhattacharyya, K, Bhutta, ZA, Bibi, S, Bintoro, BS, Bitaraf, S, Bodicha, BBA, Boloor, A, Bouaoud, S, Brown, J, Burkart, K, Butt, NS, Butt, MH, Camera, LA, Rincon, JCC, Cao, C, Carvalho, AF, Carvalho, M, Chakraborty, PA, Chandrasekar, EK, Chang, J-C, Charalampous, P, Charan, J, Chattu, VK, Chekole, BM, Chitheer, A, Cho, DY, Chopra, H, Christopher, DJ, Chukwu, IS, Cruz-Martins, N, Dadras, O, Dahlawi, SMA, Dai, X, Damiani, G, Darmstadt, GL, Soltani, RDC, Darwesh, AM, Das, S, Dastiridou, A, Debela, SA, Dehghan, A, Demeke, GM, Demetriades, AK, Demissie, S, Dessalegn, FN, Desta, AA, Dianatinasab, M, Diao, N, da Silva, DD, Diaz, D, Digesa, LE, Diress, M, Djalalinia, S, Linh, PD, Dodangeh, M, Doku, PN, Dongarwar, D, Dsouza, HL, Eini, E, Ekholuenetale, M, Ekundayo, TC, Elagali, AEM, Elbahnasawy, MA, Elhabashy, HR, Elhadi, M, Zaki, MES, Enyew, DB, Erkhembayar, R, Eskandarieh, S, Etaee, F, Fagbamigbe, AF, Faris, PS, Farmany, A, Faro, A, Farzadfar, F, Fatehizadeh, A, Fereshtehnejad, S-M, Feroze, AH, Fetensa, G, Feyisa, BR, Filip, I, Fischer, F, Foroutan, B, Foroutan, M, Fowobaje, KR, Franklin, RC, Fukumoto, T, Gaal, PA, Gadanya, MA, Galali, Y, Galehdar, N, Ganesan, B, Garg, T, Gebrehiwot, MGD, Gebremariam, YH, Gela, YY, Gerema, U, Ghafourifard, M, Ghamari, S-H, Ghanbari, R, Nour, MG, Gholamalizadeh, M, Gholami, A, Gholamrezanezhad, A, Ghozy, S, Gilani, SA, Gill, TK, Gine-Vazquez, I, Girma, ZA, Glasbey, JC, Glozah, FN, Golechha, M, Goleij, P, Grivna, M, Guadie, HA, Gunawardane, DA, Guo, Y, Gupta, VB, Gupta, S, Gupta, B, Gupta, VK, Haj-Mirzaian, A, Halwani, R, Hamadeh, RR, Hameed, S, Hanfore, LK, Hanif, A, Hargono, A, Harlianto, NI, Harorani, M, Hasaballah, AI, Hasan, SMM, Hassan, A, Hassanipour, S, Hassankhani, H, Havmoeller, RJ, Hay, SI, Heidari, M, Hendrie, D, Heyi, DZ, Hiraike, Y, Holla, R, Horita, N, Hossain, SJ, Hossain, MBH, Shabanan, SH, Hosseinzadeh, M, Hostiuc, S, Hoveidaei, AH, Hsiao, AK, Hussain, S, Hussein, A, Ibitoye, SE, Ilesanmi, OS, Ilic, IM, Ilic, MD, Imani, B, Immurana, M, Inbaraj, LR, Islam, SMS, Islam, RM, Islam, MM, Ismail, NE, Merin, LJ, Jahrami, H, Jakovljevic, M, Janodia, MD, Javaheri, T, Jayapal, SK, Jayarajah, UU, Jayaraman, S, Jeganathan, J, Jemal, B, Jha, RP, Jonas, JB, Joo, T, Joseph, N, Jozwiak, JJ, Jurisson, M, Kabir, A, Kadashetti, V, Kadir, DH, Kalankesh, LR, Kalhor, R, Kamal, VK, Kamath, R, Kandel, H, Kantar, RS, Kapoor, N, Karami, H, Karaye, IM, Karkhah, S, Katoto, PDMC, Kauppila, JH, Kayode, GA, Keikavoosi-Arani, L, Keskin, C, Khader, YS, Khajuria, H, Khammarnia, M, Khan, EA, Khan, MN, Khan, M, Khan, YH, Khan, IA, Khan, A, Khan, MAB, Khanali, J, Khatatbeh, MM, Kashani, HRK, Khazaie, H, Khubchandani, J, Kifle, ZD, Kim, J, Kim, YJ, Kisa, S, Kisa, A, Kneib, CJ, Kompani, F, Koohestani, HR, Koul, PA, Laxminarayana, SLK, Koyanagi, A, Krishan, K, Krishnamoorthy, V, Bicer, BK, Kumar, N, Kumar, M, Kurmi, OP, Laflamme, L, Lam, J, Landires, I, Larijani, B, Lasrado, S, Lauriola, P, La Vecchia, C, Lee, SWH, Lee, YH, Lee, S-W, Lee, W-C, Legesse, SM, Li, S, Lim, SS, Lorenzovici, L, Luke, AO, Madadizadeh, F, Madureira-Carvalho, AM, Abd El Razek, MM, Mahjoub, S, Mahmoodpoor, A, Mahmoudi, R, Mahmoudimanesh, M, Majeed, A, Makki, A, Rad, EM, Malekpour, M-R, Malik, AA, Mallhi, TH, Malta, DC, Mansouri, B, Mansournia, MA, Mathews, E, Maulud, SQ, Mazingi, D, Nasab, EM, Mendoza-Cano, O, Menezes, RG, Mengistu, DA, Mentis, A-FA, Meretoja, A, Mesregah, MK, Mestrovic, T, Gomide Nogueira de Sa, ACM, Miller, TR, Mirghaderi, SP, Mirica, A, Mirmoeeni, S, Mirrakhimov, EM, Mirza, M, Misra, S, Mithra, P, Mittal, C, Moberg, ME, Mohammadi, M, Mohammadi, S, Mohammadi, E, Mohammadpourhodki, R, Mohammed, S, Mohammed, TA, Mohseni, M, Mokdad, AH, Momtazmanesh, S, Monasta, L, Moni, MA, Moreira, RS, Morrison, SD, Mostafavi, E, Isfahani, HM, Mubarik, S, Muccioli, L, Mukherjee, S, Mulita, F, Mustafa, G, Nagarajan, AJ, Naimzada, MD, Nangia, V, Nassereldine, H, Natto, ZS, Nayak, BP, Negoi, I, Nejadghaderi, SA, Nepal, S, Kandel, SN, Noroozi, N, Nunez-Samudio, V, Nzoputam, OJ, Nzoputam, CI, Ochir, C, Odhiambo, JN, Odukoya, OO, Okati-Aliabad, H, Okonji, OC, Olagunju, AT, Bali, AO, Omer, E, Otoiu, A, Otstavnov, SS, Otstavnov, N, Oumer, B, Owolabi, MO, Mahesh, PA, Padron-Monedero, A, Padubidri, JR, Fallahy, MTP, Panda-Jonas, S, Pandi-Perumal, SR, Pardhan, S, Park, E-K, Patel, SK, Pathan, AR, Pati, S, Paudel, U, Pawar, S, Pedersini, P, Peres, MFP, Petcu, I-R, Phillips, MR, Pillay, JD, Piracha, ZZ, Poursadeqiyan, M, Pourtaheri, N, Qattea, I, Radfar, A, Rafiee, A, Raghav, PR, Rahim, F, Rahman, MA, Rahman, FS, Rahman, M, Rahmani, AM, Rahmani, S, Moolambally, SR, Ramazanu, S, Ramezanzadeh, K, Rana, J, Rana, SM, Rao, CR, Rao, SJ, Rashedi, V, Rashidi, M-M, Rastogi, P, Rasul, A, Rawaf, S, Rawaf, DL, Rawal, L, Rawassizadeh, R, Rezaei, N, Rezaeian, M, Rezapour, A, Riad, A, Riaz, M, Rickard, J, Buendia Rodriguez, JA, Roever, L, Ronfani, L, Roy, B, Manjula, S, Saad, AMA, Sabour, S, Sabzmakan, L, Saddik, B, Sadeghi, M, Saeb, MR, Saeed, U, Moghaddam, SS, Safi, SZ, Sahiledengle, B, Sahoo, H, Sahraian, MA, Saki, M, Salamati, P, Salehi, S, Salem, MR, Samy, AM, Sanabria, J, Santric-Milicevic, MM, Saqib, MAN, Sarikhani, Y, Sarveazad, A, Sathian, B, Satpathy, M, Saya, GK, Ceola Schneider, IJ, Schwebel, DC, Seddighi, H, Senthilkumaran, S, Seylani, A, Shabaninejad, H, Shafeghat, M, Shah, PA, Shahabi, S, Shahbandi, A, Shahraki-Sanavi, F, Shaikh, MA, Shaker, E, Shams-Beyranvand, M, Shanawaz, M, Shannawaz, M, Sharew, MMS, Sharma, N, Shashamo, BB, Shayan, M, Sheikhi, RA, Shen, J, Shetty, BSK, Shetty, PH, Shin, JI, Shitaye, NA, Shivakumar, KM, Shobeiri, P, Shorofi, SA, Shrestha, S, Siabani, S, Sidemo, NB, Simegn, W, Sinaei, E, Singh, P, Sinto, R, Siraj, MS, Skryabin, VY, Skryabina, AA, Sleet, DA, Chandan, SN, Socea, B, Solmi, M, Solomon, Y, Song, Y, Sousa, RARC, Soyiri, IN, Stokes, MA, Suleman, M, Abdulkader, RS, Sun, J, Tabares-Seisdedos, R, Tabatabaei, SM, Tabish, M, Taheri, E, Soodejani, MT, Tampa, M, Tan, K-K, Tarigan, IU, Tariqujjaman, M, Tat, NY, Tat, VY, Tavakoli, A, Tefera, BN, Tefera, YM, Temesgen, G, Temsah, M-H, Thangaraju, P, Thapar, R, Thomas, NK, Ticoalu, JHV, Tincho, MB, Tiyuri, A, Togtmol, M, Tovani-Palone, MR, Mai, TNT, Ullah, S, Ullah, I, Umakanthan, S, Unnikrishnan, B, Upadhyay, E, Tahbaz, SV, Valdez, PR, Vasankari, TJ, Vaziri, S, Veroux, M, Vervoort, D, Violante, FS, Vlassov, V, Linh, GV, Waheed, Y, Wang, Y, Wang, Y-P, Wang, C, Wiangkham, T, Wickramasinghe, ND, Woday, AT, Wu, A-M, Yahya, GAT, Jabbari, SHY, Yang, L, Yaya, S, Yigit, A, Yigit, V, Yisihak, E, Yonemoto, N, You, Y, Younis, MZ, Yu, C, Yunusa, I, Yusefi, H, Zahir, M, Bin Zaman, S, Zare, I, Zarea, K, Zastrozhin, MS, Zhang, Z-J, Zhang, Y, Ziapour, A, Zodpey, S, Zoladl, M, Patton, GC, Ivers, RQ, Peden, AE, Cullen, P, Francis, KL, Moeller, H, Peden, MM, Ye, P, Tian, M, Zou, Z, Sawyer, SM, Aali, A, Abbasi-Kangevari, Z, Abbasi-Kangevari, M, Abdelmasseh, M, Abdoun, M, Abd-Rabu, R, Abdulah, DM, Abdurehman, AM, Abebe, G, Abebe, AM, Abedi, A, Abidi, H, Aboagye, RG, Ali, HA, Abu-Gharbieh, E, Adane, DE, Adane, TD, Addo, IY, Adewole, OG, Adhikari, S, Adnan, M, Adnani, QES, Afolabi, AAB, Afzal, S, Afzal, MS, Aghdam, ZB, Ahinkorah, BO, Ahmad, AR, Ahmad, T, Ahmad, S, Ahmadi, A, Ahmed, H, Ahmed, MB, Ahmed, A, Ahmed, JQ, Rashid, TA, Aithala, JP, Aji, B, Akhlaghdoust, M, Alahdab, F, Alanezi, FM, Alemayehu, A, Al Hamad, H, Ali, SS, Ali, L, Alimohamadi, Y, Alipour, V, Aljunid, SM, Almidani, L, Almustanyir, S, Altirkawi, KA, Alvis-Zakzuk, NJ, Ameyaw, EK, Amin, TT, Amir-Behghadami, M, Amiri, S, Amiri, H, Anagaw, TF, Andrei, T, Andrei, CL, Anvari, D, Anwar, SL, Anyasodor, AE, Arabloo, J, Arab-Zozani, M, Arja, A, Arulappan, J, Arumugam, A, Aryannejad, A, Asgary, S, Ashraf, T, Athari, SS, Atreya, A, Attia, S, Aujayeb, A, Awedew, AF, Azadnajafabad, S, Azangou-Khyavy, M, Azari, S, Jafari, AA, Azizi, H, Azzam, AY, Badiye, AD, Baghcheghi, N, Bagherieh, S, Baig, AA, Bakkannavar, SM, Balta, AB, Banach, M, Banik, PC, Bansal, H, Bardhan, M, Barone-Adesi, F, Barrow, A, Bashiri, A, Baskaran, P, Basu, S, Bayileyegn, NS, Bekel, AA, Bekele, AB, Bendak, S, Bensenor, IM, Berhie, AY, Bhagat, DS, Bhagavathula, AS, Bhardwaj, P, Bhardwaj, N, Bhaskar, S, Bhat, AN, Bhattacharyya, K, Bhutta, ZA, Bibi, S, Bintoro, BS, Bitaraf, S, Bodicha, BBA, Boloor, A, Bouaoud, S, Brown, J, Burkart, K, Butt, NS, Butt, MH, Camera, LA, Rincon, JCC, Cao, C, Carvalho, AF, Carvalho, M, Chakraborty, PA, Chandrasekar, EK, Chang, J-C, Charalampous, P, Charan, J, Chattu, VK, Chekole, BM, Chitheer, A, Cho, DY, Chopra, H, Christopher, DJ, Chukwu, IS, Cruz-Martins, N, Dadras, O, Dahlawi, SMA, Dai, X, Damiani, G, Darmstadt, GL, Soltani, RDC, Darwesh, AM, Das, S, Dastiridou, A, Debela, SA, Dehghan, A, Demeke, GM, Demetriades, AK, Demissie, S, Dessalegn, FN, Desta, AA, Dianatinasab, M, Diao, N, da Silva, DD, Diaz, D, Digesa, LE, Diress, M, Djalalinia, S, Linh, PD, Dodangeh, M, Doku, PN, Dongarwar, D, Dsouza, HL, Eini, E, Ekholuenetale, M, Ekundayo, TC, Elagali, AEM, Elbahnasawy, MA, Elhabashy, HR, Elhadi, M, Zaki, MES, Enyew, DB, Erkhembayar, R, Eskandarieh, S, Etaee, F, Fagbamigbe, AF, Faris, PS, Farmany, A, Faro, A, Farzadfar, F, Fatehizadeh, A, Fereshtehnejad, S-M, Feroze, AH, Fetensa, G, Feyisa, BR, Filip, I, Fischer, F, Foroutan, B, Foroutan, M, Fowobaje, KR, Franklin, RC, Fukumoto, T, Gaal, PA, Gadanya, MA, Galali, Y, Galehdar, N, Ganesan, B, Garg, T, Gebrehiwot, MGD, Gebremariam, YH, Gela, YY, Gerema, U, Ghafourifard, M, Ghamari, S-H, Ghanbari, R, Nour, MG, Gholamalizadeh, M, Gholami, A, Gholamrezanezhad, A, Ghozy, S, Gilani, SA, Gill, TK, Gine-Vazquez, I, Girma, ZA, Glasbey, JC, Glozah, FN, Golechha, M, Goleij, P, Grivna, M, Guadie, HA, Gunawardane, DA, Guo, Y, Gupta, VB, Gupta, S, Gupta, B, Gupta, VK, Haj-Mirzaian, A, Halwani, R, Hamadeh, RR, Hameed, S, Hanfore, LK, Hanif, A, Hargono, A, Harlianto, NI, Harorani, M, Hasaballah, AI, Hasan, SMM, Hassan, A, Hassanipour, S, Hassankhani, H, Havmoeller, RJ, Hay, SI, Heidari, M, Hendrie, D, Heyi, DZ, Hiraike, Y, Holla, R, Horita, N, Hossain, SJ, Hossain, MBH, Shabanan, SH, Hosseinzadeh, M, Hostiuc, S, Hoveidaei, AH, Hsiao, AK, Hussain, S, Hussein, A, Ibitoye, SE, Ilesanmi, OS, Ilic, IM, Ilic, MD, Imani, B, Immurana, M, Inbaraj, LR, Islam, SMS, Islam, RM, Islam, MM, Ismail, NE, Merin, LJ, Jahrami, H, Jakovljevic, M, Janodia, MD, Javaheri, T, Jayapal, SK, Jayarajah, UU, Jayaraman, S, Jeganathan, J, Jemal, B, Jha, RP, Jonas, JB, Joo, T, Joseph, N, Jozwiak, JJ, Jurisson, M, Kabir, A, Kadashetti, V, Kadir, DH, Kalankesh, LR, Kalhor, R, Kamal, VK, Kamath, R, Kandel, H, Kantar, RS, Kapoor, N, Karami, H, Karaye, IM, Karkhah, S, Katoto, PDMC, Kauppila, JH, Kayode, GA, Keikavoosi-Arani, L, Keskin, C, Khader, YS, Khajuria, H, Khammarnia, M, Khan, EA, Khan, MN, Khan, M, Khan, YH, Khan, IA, Khan, A, Khan, MAB, Khanali, J, Khatatbeh, MM, Kashani, HRK, Khazaie, H, Khubchandani, J, Kifle, ZD, Kim, J, Kim, YJ, Kisa, S, Kisa, A, Kneib, CJ, Kompani, F, Koohestani, HR, Koul, PA, Laxminarayana, SLK, Koyanagi, A, Krishan, K, Krishnamoorthy, V, Bicer, BK, Kumar, N, Kumar, M, Kurmi, OP, Laflamme, L, Lam, J, Landires, I, Larijani, B, Lasrado, S, Lauriola, P, La Vecchia, C, Lee, SWH, Lee, YH, Lee, S-W, Lee, W-C, Legesse, SM, Li, S, Lim, SS, Lorenzovici, L, Luke, AO, Madadizadeh, F, Madureira-Carvalho, AM, Abd El Razek, MM, Mahjoub, S, Mahmoodpoor, A, Mahmoudi, R, Mahmoudimanesh, M, Majeed, A, Makki, A, Rad, EM, Malekpour, M-R, Malik, AA, Mallhi, TH, Malta, DC, Mansouri, B, Mansournia, MA, Mathews, E, Maulud, SQ, Mazingi, D, Nasab, EM, Mendoza-Cano, O, Menezes, RG, Mengistu, DA, Mentis, A-FA, Meretoja, A, Mesregah, MK, Mestrovic, T, Gomide Nogueira de Sa, ACM, Miller, TR, Mirghaderi, SP, Mirica, A, Mirmoeeni, S, Mirrakhimov, EM, Mirza, M, Misra, S, Mithra, P, Mittal, C, Moberg, ME, Mohammadi, M, Mohammadi, S, Mohammadi, E, Mohammadpourhodki, R, Mohammed, S, Mohammed, TA, Mohseni, M, Mokdad, AH, Momtazmanesh, S, Monasta, L, Moni, MA, Moreira, RS, Morrison, SD, Mostafavi, E, Isfahani, HM, Mubarik, S, Muccioli, L, Mukherjee, S, Mulita, F, Mustafa, G, Nagarajan, AJ, Naimzada, MD, Nangia, V, Nassereldine, H, Natto, ZS, Nayak, BP, Negoi, I, Nejadghaderi, SA, Nepal, S, Kandel, SN, Noroozi, N, Nunez-Samudio, V, Nzoputam, OJ, Nzoputam, CI, Ochir, C, Odhiambo, JN, Odukoya, OO, Okati-Aliabad, H, Okonji, OC, Olagunju, AT, Bali, AO, Omer, E, Otoiu, A, Otstavnov, SS, Otstavnov, N, Oumer, B, Owolabi, MO, Mahesh, PA, Padron-Monedero, A, Padubidri, JR, Fallahy, MTP, Panda-Jonas, S, Pandi-Perumal, SR, Pardhan, S, Park, E-K, Patel, SK, Pathan, AR, Pati, S, Paudel, U, Pawar, S, Pedersini, P, Peres, MFP, Petcu, I-R, Phillips, MR, Pillay, JD, Piracha, ZZ, Poursadeqiyan, M, Pourtaheri, N, Qattea, I, Radfar, A, Rafiee, A, Raghav, PR, Rahim, F, Rahman, MA, Rahman, FS, Rahman, M, Rahmani, AM, Rahmani, S, Moolambally, SR, Ramazanu, S, Ramezanzadeh, K, Rana, J, Rana, SM, Rao, CR, Rao, SJ, Rashedi, V, Rashidi, M-M, Rastogi, P, Rasul, A, Rawaf, S, Rawaf, DL, Rawal, L, Rawassizadeh, R, Rezaei, N, Rezaeian, M, Rezapour, A, Riad, A, Riaz, M, Rickard, J, Buendia Rodriguez, JA, Roever, L, Ronfani, L, Roy, B, Manjula, S, Saad, AMA, Sabour, S, Sabzmakan, L, Saddik, B, Sadeghi, M, Saeb, MR, Saeed, U, Moghaddam, SS, Safi, SZ, Sahiledengle, B, Sahoo, H, Sahraian, MA, Saki, M, Salamati, P, Salehi, S, Salem, MR, Samy, AM, Sanabria, J, Santric-Milicevic, MM, Saqib, MAN, Sarikhani, Y, Sarveazad, A, Sathian, B, Satpathy, M, Saya, GK, Ceola Schneider, IJ, Schwebel, DC, Seddighi, H, Senthilkumaran, S, Seylani, A, Shabaninejad, H, Shafeghat, M, Shah, PA, Shahabi, S, Shahbandi, A, Shahraki-Sanavi, F, Shaikh, MA, Shaker, E, Shams-Beyranvand, M, Shanawaz, M, Shannawaz, M, Sharew, MMS, Sharma, N, Shashamo, BB, Shayan, M, Sheikhi, RA, Shen, J, Shetty, BSK, Shetty, PH, Shin, JI, Shitaye, NA, Shivakumar, KM, Shobeiri, P, Shorofi, SA, Shrestha, S, Siabani, S, Sidemo, NB, Simegn, W, Sinaei, E, Singh, P, Sinto, R, Siraj, MS, Skryabin, VY, Skryabina, AA, Sleet, DA, Chandan, SN, Socea, B, Solmi, M, Solomon, Y, Song, Y, Sousa, RARC, Soyiri, IN, Stokes, MA, Suleman, M, Abdulkader, RS, Sun, J, Tabares-Seisdedos, R, Tabatabaei, SM, Tabish, M, Taheri, E, Soodejani, MT, Tampa, M, Tan, K-K, Tarigan, IU, Tariqujjaman, M, Tat, NY, Tat, VY, Tavakoli, A, Tefera, BN, Tefera, YM, Temesgen, G, Temsah, M-H, Thangaraju, P, Thapar, R, Thomas, NK, Ticoalu, JHV, Tincho, MB, Tiyuri, A, Togtmol, M, Tovani-Palone, MR, Mai, TNT, Ullah, S, Ullah, I, Umakanthan, S, Unnikrishnan, B, Upadhyay, E, Tahbaz, SV, Valdez, PR, Vasankari, TJ, Vaziri, S, Veroux, M, Vervoort, D, Violante, FS, Vlassov, V, Linh, GV, Waheed, Y, Wang, Y, Wang, Y-P, Wang, C, Wiangkham, T, Wickramasinghe, ND, Woday, AT, Wu, A-M, Yahya, GAT, Jabbari, SHY, Yang, L, Yaya, S, Yigit, A, Yigit, V, Yisihak, E, Yonemoto, N, You, Y, Younis, MZ, Yu, C, Yunusa, I, Yusefi, H, Zahir, M, Bin Zaman, S, Zare, I, Zarea, K, Zastrozhin, MS, Zhang, Z-J, Zhang, Y, Ziapour, A, Zodpey, S, Zoladl, M, Patton, GC, and Ivers, RQ
Abstract: BACKGROUND: Globally, transport and unintentional injuries persist as leading preventable causes of mortality and morbidity for adolescents. We sought to report comprehensive trends in injury-related mortality and morbidity for adolescents aged 10-24 years during the past three decades. METHODS: Using the Global Burden of Disease, Injuries, and Risk Factors 2019 Study, we analysed mortality and disability-adjusted life-years (DALYs) attributed to transport and unintentional injuries for adolescents in 204 countries. Burden is reported in absolute numbers and age-standardised rates per 100 000 population by sex, age group (10-14, 15-19, and 20-24 years), and sociodemographic index (SDI) with 95% uncertainty intervals (UIs). We report percentage changes in deaths and DALYs between 1990 and 2019. FINDINGS: In 2019, 369 061 deaths (of which 214 337 [58%] were transport related) and 31·1 million DALYs (of which 16·2 million [52%] were transport related) among adolescents aged 10-24 years were caused by transport and unintentional injuries combined. If compared with other causes, transport and unintentional injuries combined accounted for 25% of deaths and 14% of DALYs in 2019, and showed little improvement from 1990 when such injuries accounted for 26% of adolescent deaths and 17% of adolescent DALYs. Throughout adolescence, transport and unintentional injury fatality rates increased by age group. The unintentional injury burden was higher among males than females for all injury types, except for injuries related to fire, heat, and hot substances, or to adverse effects of medical treatment. From 1990 to 2019, global mortality rates declined by 34·4% (from 17·5 to 11·5 per 100 000) for transport injuries, and by 47·7% (from 15·9 to 8·3 per 100 000) for unintentional injuries. However, in low-SDI nations the absolute number of deaths increased (by 80·5% to 42 774 for transport injuries and by 39·4% to 31 961 for unintentional injuries). In the high-SDI quintile in 2010-19
Published: 2022

3. Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019

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Abdelazeem M Algammal, Fadwa Alhalaiqa Naji Alhalaiqa, Robert Kaba Alhassan, Beriwan Abdulqadir Ali, Liaqat Ali, Musa Mohammed Ali, Syed Shujait Ali, Yousef Alimohamadi, Vahid Alipour, Adel Al-Jumaily, Syed Mohamed Aljunid, Sami Almustanyir, Rajaa M Al-Raddadi, Rami H Hani Al-Rifai, Saif Aldeen S AlRyalat, Nelson Alvis-Guzman, Nelson J Alvis-Zakzuk, Edward Kwabena Ameyaw, Javad Javad Aminian Dehkordi, John H Amuasi, Dickson A Amugsi, Etsay Woldu Anbesu, Adnan Ansar, Anayochukwu Edward Anyasodor, Jalal Arabloo, Demelash Areda, Ayele Mamo Argaw, Zeleke Gebru Argaw, Judie Arulappan, Raphael Taiwo Aruleba, Mulusew A Asemahagn, Seyyed Shamsadin Athari, Daniel Atlaw, Engi F Attia, Sameh Attia, Avinash Aujayeb, Tewachew Awoke, Tegegn Mulatu Ayana, Martin Amogre Ayanore, Sina Azadnajafabad, Mohammadreza Azangou-Khyavy, Samad Azari, Amirhossein Azari Jafari, Muhammad Badar, Ashish D Badiye, Nayereh Baghcheghi, Sara Bagherieh, Atif Amin Baig, Maciej Banach, Indrajit Banerjee, Mainak Bardhan, 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Subjects: Adult, Male, Global Health, Time, Global Burden of Disease, SDG 3 - Good Health and Well-being, Risk Factors, RA0421, RA0421 Public health. Hygiene. Preventive Medicine, Humans, Ambient air-quality, Child, Respiratory Tract Infections, Aged, Aged, 80 and over, MCC, Sex Characteristics, Malnutrition, Pyridinolcarbamate, Bayes Theorem, 3rd-DAS, 3142 Public health care science, environmental and occupational health, Infectious Diseases, 3121 General medicine, internal medicine and other clinical medicine, Child, Preschool, Female, Particulate Matter, Quality-Adjusted Life Years, Covid-19, LRI
Abstract: Funding: Bill & Melinda Gates Foundation. Background: The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years and adults has not been studied as comprehensively as it has been in children younger than 5 years. We assessed the burden and trends of LRIs and risk factors across all age groups by sex, for 204 countries and territories. Methods: In this analysis of data for the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we used clinician-diagnosed pneumonia or bronchiolitis as our case definition for LRIs. We included International Classification of Diseases 9th edition codes 079.6, 466–469, 470.0, 480–482.8, 483.0–483.9, 484.1–484.2, 484.6–484.7, and 487–489 and International Classification of Diseases 10th edition codes A48.1, A70, B97.4–B97.6, J09–J15.8, J16–J16.9, J20–J21.9, J91.0, P23.0–P23.4, and U04–U04.9. We used the Cause of Death Ensemble modelling strategy to analyse 23 109 site-years of vital registration data, 825 site-years of sample vital registration data, 1766 site-years of verbal autopsy data, and 681 site-years of mortality surveillance data. We used DisMod-MR 2.1, a Bayesian meta-regression tool, to analyse age–sex-specific incidence and prevalence data identified via systematic reviews of the literature, population-based survey data, and claims and inpatient data. Additionally, we estimated age–sex-specific LRI mortality that is attributable to the independent effects of 14 risk factors. Findings: Globally, in 2019, we estimated that there were 257 million (95% uncertainty interval [UI] 240–275) LRI incident episodes in males and 232 million (217–248) in females. In the same year, LRIs accounted for 1·30 million (95% UI 1·18–1·42) male deaths and 1·20 million (1·07–1·33) female deaths. Age-standardised incidence and mortality rates were 1·17 times (95% UI 1·16–1·18) and 1·31 times (95% UI 1·23–1·41) greater in males than in females in 2019. Between 1990 and 2019, LRI incidence and mortality rates declined at different rates across age groups and an increase in LRI episodes and deaths was estimated among all adult age groups, with males aged 70 years and older having the highest increase in LRI episodes (126·0% [95% UI 121·4–131·1]) and deaths (100·0% [83·4–115·9]). During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). The leading risk factors for LRI mortality varied across age groups and sex. More than half of global LRI deaths in children younger than 5 years were attributable to child wasting (population attributable fraction [PAF] 53·0% [95% UI 37·7–61·8] in males and 56·4% [40·7–65·1] in females), and more than a quarter of LRI deaths among those aged 5–14 years were attributable to household air pollution (PAF 26·0% [95% UI 16·6–35·5] for males and PAF 25·8% [16·3–35·4] for females). PAFs of male LRI deaths attributed to smoking were 20·4% (95% UI 15·4–25·2) in those aged 15–49 years, 30·5% (24·1–36·9) in those aged 50–69 years, and 21·9% (16·8–27·3) in those aged 70 years and older. PAFs of female LRI deaths attributed to household air pollution were 21·1% (95% UI 14·5–27·9) in those aged 15–49 years and 18·2% (12·5–24·5) in those aged 50–69 years. For females aged 70 years and older, the leading risk factor, ambient particulate matter, was responsible for 11·7% (95% UI 8·2–15·8) of LRI deaths. Interpretation: The patterns and progress in reducing the burden of LRIs and key risk factors for mortality varied across age groups and sexes. The progress seen in children younger than 5 years was clearly a result of targeted interventions, such as vaccination and reduction of exposure to risk factors. Similar interventions for other age groups could contribute to the achievement of multiple Sustainable Development Goals targets, including promoting wellbeing at all ages and reducing health inequalities. Interventions, including addressing risk factors such as child wasting, smoking, ambient particulate matter pollution, and household air pollution, would prevent deaths and reduce health disparities. Publisher PDF
Published: 2022

4. The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019

Author: Elysia M Alvarez, Lisa M Force, Rixing Xu, Kelly Compton, Dan Lu, Hannah Jacqueline Henrikson, Jonathan M Kocarnik, James D Harvey, Alyssa Pennini, Frances E Dean, Weijia Fu, Martina T Vargas, Theresa H M Keegan, Hany Ariffin, Ronald D Barr, Yana Arturovna Erdomaeva, D Sanjeeva Gunasekera, Yetunde O John-Akinola, Tyler G Ketterl, Tezer Kutluk, Marcio Henrique Malogolowkin, Prashant Mathur, Venkatraman Radhakrishnan, Lynn Ann Gloeckler Ries, Carlos Rodriguez-Galindo, Garik Barisovich Sagoyan, Iyad Sultan, Behzad Abbasi, Mohsen Abbasi-Kangevari, Zeinab Abbasi-Kangevari, Hedayat Abbastabar, Michael Abdelmasseh, Sherief Abd-Elsalam, Amir Abdoli, Haimanot Abebe, Aidin Abedi, Hassan Abidi, Hassan Abolhassani, Hiwa Abubaker Ali, Eman Abu-Gharbieh, Basavaprabhu Achappa, Juan Manuel Acuna, Isaac Akinkunmi Adedeji, Oyelola A Adegboye, Qorinah Estiningtyas Sakilah Adnani, Shailesh M Advani, Muhammad Sohail Afzal, Mohamad Aghaie Meybodi, Bahman Ahadinezhad, Bright Opoku Ahinkorah, Sajjad Ahmad, Sepideh Ahmadi, Muktar Beshir Ahmed, Tarik Ahmed Rashid, Yusra Ahmed Salih, Wajeeha Aiman, Gizachew Taddesse Akalu, Hanadi Al Hamad, Fares Alahdab, Abdulhadi A AlAmodi, Fahad Mashhour Alanezi, Turki M Alanzi, Adugnaw Zeleke Alem, Dejene Tsegaye Alem, Yosef Alemayehu, Fadwa Naji Alhalaiqa, Robert Kaba Alhassan, Saqib Ali, Gianfranco Alicandro, Vahid Alipour, Syed Mohamed Aljunid, Motasem Alkhayyat, Sunitha Alluri, Nihad A Almasri, Sadeq Ali Al-Maweri, Sami Almustanyir, Rajaa M Al-Raddadi, Nelson Alvis-Guzman, Edward Kwabena Ameyaw, Saeed Amini, Hubert Amu, Robert Ancuceanu, Catalina Liliana Andrei, Tudorel Andrei, Fereshteh Ansari, Alireza Ansari-Moghaddam, Davood Anvari, Anayochukwu Edward Anyasodor, Jalal Arabloo, Morteza Arab-Zozani, Ayele Mamo Argaw, Muhammad Arshad, Judie Arulappan, Armin Aryannejad, Zatollah Asemi, Mohammad Asghari Jafarabadi, Mohammad Reza Atashzar, Prince Atorkey, Alok Atreya, Sameh Attia, Avinash Aujayeb, Marcel Ausloos, Leticia Avila-Burgos, Atalel Fentahun Awedew, Beatriz Paulina Ayala Quintanilla, Alemu Degu Ayele, Solomon Shitu Ayen, Mohammed A Azab, Sina Azadnajafabad, Hiva Azami, Mohammadreza Azangou-Khyavy, Amirhossein Azari Jafari, Ghasem Azarian, Ahmed Y Azzam, Saeed Bahadory, Jianjun Bai, Atif Amin Baig, Jennifer L Baker, Maciej Banach, Till Winfried Bärnighausen, Francesco Barone-Adesi, Fabio Barra, Amadou Barrow, Huda Basaleem, Abdul-Monim Mohammad Batiha, Masoud Behzadifar, Niguss Cherie Bekele, Rebuma Belete, Uzma Iqbal Belgaumi, Arielle Wilder Bell, Alemshet Yirga Berhie, Devidas S Bhagat, Akshaya Srikanth Bhagavathula, Nikha Bhardwaj, Pankaj Bhardwaj, Sonu Bhaskar, Krittika Bhattacharyya, Vijayalakshmi S Bhojaraja, Sadia Bibi, Ali Bijani, Antonio Biondi, Setognal Birara, Tone Bjørge, Obasanjo Afolabi Bolarinwa, Srinivasa Rao Bolla, Archith Boloor, Dejana Braithwaite, Hermann Brenner, Norma B Bulamu, Katrin Burkart, Maria Teresa Bustamante-Teixeira, Nadeem Shafique Butt, Zahid A Butt, Florentino Luciano Caetano dos Santos, Chao Cao, Yin Cao, Giulia Carreras, Ferrán Catalá-López, Francieli Cembranel, Ester Cerin, Raja Chandra Chakinala, Promit Ananyo Chakraborty, Vijay Kumar Chattu, Pankaj Chaturvedi, Akhilanand Chaurasia, Prachi P Chavan, Odgerel Chimed-Ochir, Jee-Young Jasmine Choi, Devasahayam J Christopher, Dinh-Toi Chu, Michael T Chung, Joao Conde, Vera Marisa Costa, Omar B Da'ar, Omid Dadras, Saad M A Dahlawi, Xiaochen Dai, Giovanni Damiani, Emanuele D'Amico, Lalit Dandona, Rakhi Dandona, Parnaz Daneshpajouhnejad, Amira Hamed Darwish, Ahmad Daryani, Fernando Pio De la Hoz, Sisay Abebe Debela, Takele Gezahegn G Demie, Getu Debalkie Demissie, Zeleke Geto Demissie, Edgar Denova-Gutiérrez, Meseret Derbew Molla, Rupak Desai, Abebaw Alemayehu Desta, Deepak Dhamnetiya, Samath Dhamminda Dharmaratne, Mandira Lamichhane Dhimal, Meghnath Dhimal, Mostafa Dianatinasab, Mojtaba Didehdar, Mengistie Diress, Shirin Djalalinia, Huyen Phuc Do, Saeid Doaei, Fariba Dorostkar, Wendel Mombaque dos Santos, Thomas M Drake, Michael Ekholuenetale, Iman El Sayed, Maysaa El Sayed Zaki, Maha El Tantawi, Hassan El-Abid, Mostafa Ahmed Elbahnasawy, Iffat Elbarazi, Hala Rashad Elhabashy, Muhammed Elhadi, Shaimaa I El-Jaafary, Daniel Berhanie Enyew, Ryenchindorj Erkhembayar, Babak Eshrati, Sharareh Eskandarieh, Mohammed Faisaluddin, Jawad Fares, Umar Farooque, Abidemi Omolara Fasanmi, Wafa Fatima, José Miguel P Ferreira de Oliveira, Simone Ferrero, Lorenzo Ferro Desideri, Getahun Fetensa, Irina Filip, Florian Fischer, James L Fisher, Masoud Foroutan, Takeshi Fukumoto, Peter Andras Gaal, Mohamed M Gad, Piyada Gaewkhiew, Silvano Gallus, Tushar Garg, Teferi Gebru Gebremeskel, Belete Negese Belete Gemeda, Tamiru Getachew, Mansour Ghafourifard, Seyyed-Hadi Ghamari, Ahmad Ghashghaee, Fariba Ghassemi, Nermin Ghith, Ali Gholami, Jamshid Gholizadeh Navashenaq, Syed Amir Gilani, Themba G Ginindza, Abraham Tamirat Gizaw, James C Glasbey, Amit Goel, Mahaveer Golechha, Pouya Goleij, Davide Golinelli, Sameer Vali Gopalani, Giuseppe Gorini, Houman Goudarzi, Bárbara Niegia Garcia Goulart, Ayman Grada, Mohammed Ibrahim Mohialdeen Gubari, Maximiliano Ribeiro Guerra, Avirup Guha, Bhawna Gupta, Sapna Gupta, Veer Bala Gupta, Vivek Kumar Gupta, Rasool Haddadi, Nima Hafezi-Nejad, Alemayehu Hailu, Arvin Haj-Mirzaian, Rabih Halwani, Randah R Hamadeh, Mitiku Teshome Hambisa, Sajid Hameed, Samer Hamidi, Shafiul Haque, Sanam Hariri, Josep Maria Haro, Ahmed I Hasaballah, S M Mahmudul Hasan, Seyedeh Melika Hashemi, Treska S Hassan, Soheil Hassanipour, Simon I Hay, Khezar Hayat, Sultan H Hebo, Golnaz Heidari, Mohammad Heidari, Brenda Yuliana Herrera-Serna, Claudiu Herteliu, Demisu Zenbaba Heyi, Kamal Hezam, Michael K Hole, Ramesh Holla, Nobuyuki Horita, Md Mahbub Hossain, Mohammad Bellal Hossain, Mohammad-Salar Hosseini, Mostafa Hosseini, Ali Hosseinzadeh, Mehdi Hosseinzadeh, Mihaela Hostiuc, Sorin Hostiuc, Mowafa Househ, Mohamed Hsairi, Junjie Huang, Nawfal R Hussein, Bing-Fang Hwang, Segun Emmanuel Ibitoye, Olayinka Stephen Ilesanmi, Irena M Ilic, Milena D Ilic, Kaire Innos, Lalu Muhammad Irham, Rakibul M Islam, Sheikh Mohammed Shariful Islam, Nahlah Elkudssiah Ismail, Gaetano Isola, Masao Iwagami, Louis Jacob, Farhad Jadidi-Niaragh, Vardhmaan Jain, Mihajlo Jakovljevic, Roksana Janghorban, Amirreza Javadi Mamaghani, Shubha Jayaram, Ranil Jayawardena, Seyed Behzad Jazayeri, Rime Jebai, Ravi Prakash Jha, Tamas Joo, Nitin Joseph, Farahnaz Joukar, Mikk Jürisson, Billingsley Kaambwa, Ali Kabir, Leila R Kalankesh, Feroze Kaliyadan, Zul Kamal, Ashwin Kamath, Himal Kandel, Sitanshu Sekhar Kar, Ibraheem M Karaye, Amirali Karimi, Bekalu Getnet Kassa, Joonas H Kauppila, Phillip M Kemp Bohan, Andre Pascal Kengne, Amene Abebe Kerbo, Mohammad Keykhaei, Yousef Saleh Khader, Himanshu Khajuria, Nastaran Khalili, Neda Khalili, Ejaz Ahmad Khan, Gulfaraz Khan, Maseer Khan, Md Nuruzzaman Khan, Moien AB Khan, Javad Khanali, Maryam Khayamzadeh, Omid Khosravizadeh, Jagdish Khubchandani, Roba Khundkar, Min Seo Kim, Yun Jin Kim, Adnan Kisa, Sezer Kisa, Katarzyna Kissimova-Skarbek, Ali-Asghar Kolahi, Jacek A Kopec, Rajasekaran Koteeswaran, Sindhura Lakshmi Koulmane Laxminarayana, Ai Koyanagi, Nuworza Kugbey, G Anil Kumar, Nithin Kumar, Alexander Kwarteng, Carlo La Vecchia, Qing Lan, Iván Landires, Savita Lasrado, Paolo Lauriola, Caterina Ledda, Sang-woong Lee, Wei-Chen Lee, Yeong Yeh Lee, Yo Han Lee, James Leigh, Elvynna Leong, Bingyu Li, Jiarui Li, Ming-Chieh Li, Stephen S Lim, Xuefeng Liu, Stany W Lobo, Joana A Loureiro, Alessandra Lugo, Raimundas Lunevicius, Hassan Magdy Abd El Razek, Muhammed Magdy Abd El Razek, Morteza Mahmoudi, Azeem Majeed, Alaa Makki, Shilpa Male, Mohammad-Reza Malekpour, Reza Malekzadeh, Ahmad Azam Malik, Mohammed A Mamun, Navid Manafi, Fariborz Mansour-Ghanaei, Borhan Mansouri, Mohammad Ali Mansournia, Santi Martini, Seyedeh Zahra Masoumi, Clara N Matei, Manu Raj Mathur, Colm McAlinden, Ravi Mehrotra, Walter Mendoza, Ritesh G Menezes, Alexios-Fotios A Mentis, Tuomo J 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Mpundu-Kaambwa C., Mubarik S., Mwanri L., Nabhan A.F., Nagaraju S.P., Nagata C., Naghavi M., Naimzada M.D., Naldi L., Nangia V., Naqvi A.A., Narasimha Swamy S., Narayana A.I., Nayak B.P., Nayak V.C., Nazari J., Nduaguba S.O., Negoi I., Negru S.M., Nejadghaderi S.A., Nepal S., Neupane Kandel S., Nggada H.A., Nguyen C.T., Nnaji C.A., Nosrati H., Nouraei H., Nowroozi A., Nunez-Samudio V., Nwatah V.E., Nzoputam C.I., Oancea B., Odukoya O.O., Oguntade A.S., Oh I.-H., Olagunju A.T., Olagunju T.O., Olakunde B.O., Oluwasanu M.M., Omar E., Omar Bali A., Ong S., Onwujekwe O.E., Ortega-Altamirano D.V., Otstavnov N., Otstavnov S.S., Oumer B., Owolabi M.O., P A M., Padron-Monedero A., Padubidri J.R., Pakshir K., Pana A., Pandey A., Pardhan S., Pashazadeh Kan F., Pasovic M., Patel J.R., Pati S., Pattanshetty S.M., Paudel U., Pereira R.B., Peres M.F.P., Perianayagam A., Postma M.J., Pourjafar H., Pourshams A., Prashant A., Pulakunta T., Qadir M.M.F.F., Rabiee M., Rabiee N., Radfar A., Radhakrishnan R.A., Rafiee A., Rafiei A., Rafiei S., Rahim F., Rahimzadeh S., Rahman M., Rahman M.A., Rahmani A.M., Rajesh A., Ramezani-Doroh V., Ranabhat K., Ranasinghe P., Rao C.R., Rao S.J., Rashedi S., Rashidi M., Rashidi M.-M., Rath G.K., Rawaf D.L., Rawaf S., Rawal L., Rawassizadeh R., Razeghinia M.S., Regasa M.T., Renzaho A.M.N., Rezaei M., Rezaei N., Rezaeian M., Rezapour A., Rezazadeh-Khadem S., Riad A., Rios Lopez L.E., Rodriguez J.A.B., Ronfani L., Roshandel G., Rwegerera G.M., Saber-Ayad M.M., Sabour S., Saddik B., Sadeghi E., Sadeghian S., Saeed U., Sahebkar A., Saif-Ur-Rahman K.M., Sajadi S.M., Salahi S., Salehi S., Salem M.R., Salimzadeh H., Samy A.M., Sanabria J., Sanmarchi F., Sarveazad A., Sathian B., Sawhney M., Sawyer S.M., Saylan M., Schneider I.J.C., Seidu A.-A., Sekerija M., Sendo E.G., Sepanlou S.G., Seylani A., Seyoum K., Sha F., Shafaat O., Shaikh M.A., Shamsoddin E., Shannawaz M., Sharma R., Sheikhbahaei S., Shetty A., Shetty B.S.K., Shetty P.H., Shin J.I., Shirkoohi R., Shivakumar K.M., Shobeiri P., Siabani S., Sibhat M.M., Siddappa Malleshappa S.K., Sidemo N.B., Silva D.A.S., Silva Julian G., Singh A.D., Singh J.A., Singh J.K., Singh S., Sinke A.H., Sintayehu Y., Skryabin V.Y., Skryabina A.A., Smith L., Sofi-Mahmudi A., Soltani-Zangbar M.S., Song S., Spurlock E.E., Steiropoulos P., Straif K., Subedi R., Sufiyan M.B., Suliankatchi Abdulkader R., Sultana S., Szerencses V., Szocska M., Tabaeian S.P., Tabares-Seisdedos R., Tabary M., Tabuchi T., Tadbiri H., Taheri M., Taherkhani A., Takahashi K., Tampa M., Tan K.-K., Tat V.Y., Tavakoli A., Tbakhi A., Tehrani-Banihashemi A., Temsah M.-H., Tesfay F.H., Tesfaye B., Thakur J.S., Thapar R., Thavamani A., Thiyagarajan A., Thomas N., Tobe-Gai R., Togtmol M., Tohidast S.A., Tohidinik H.R., Tolani M.A., Tollosa D.N., Touvier M., Tovani-Palone M.R., Traini E., Tran B.X., Tran M.T.N., Tripathy J.P., Tusa B.S., Ukke G.G., Ullah I., Ullah S., Umapathi K.K., Unnikrishnan B., Upadhyay E., Ushula T.W., Vacante M., Valadan Tahbaz S., Varthya S.B., Veroux M., Villeneuve P.J., Violante F.S., Vlassov V., Vu G.T., Waheed Y., Wang N., Ward P., Weldesenbet A.B., Wen Y.F., Westerman R., Winkler A.S., Wubishet B.L., Xu S., Yahyazadeh Jabbari S.H., Yang L., Yaya S., Yazdi-Feyzabadi V., Yazie T.S., Yehualashet S.S., Yeshaneh A., Yeshaw Y., Yirdaw B.W., Yonemoto N., Younis M.Z., Yousefi Z., Yu C., Yunusa I., Zadnik V., Zahir M., Zahirian Moghadam T., Zamani M., Zamanian M., Zandian H., Zare F., Zastrozhin M.S., Zastrozhina A., Zhang J., Zhang Z.-J., Ziapour A., Zoladl M., Murray C.J.L., Fitzmaurice C., Bleyer A., Bhakta N., Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Value, Affordability and Sustainability (VALUE), Microbes in Health and Disease (MHD), NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), HUS Comprehensive Cancer Center, University of Helsinki, Bill & Melinda Gates Foundation, American Lebanese Syrian Associated Charities, St. Baldrick's Foundation, NIH - National Cancer Institute (NCI) (Estados Unidos), Epidemiologie, and RS: NUTRIM - R3 - Respiratory & Age-related Health
Subjects: adolescent cancer, global burden of disease, epidemiology, Adult, Male, Adolescent, 3122 Cancers, UNITED-STATES, Disability-Adjusted Life Year, Adolescents, Socioeconomic Factor, Global Health, Global Burden of Disease, Young Adult, Life Expectancy, SDG 3 - Good Health and Well-being, Risk Factors, WORLDWIDE, Neoplasms, Cause of Death, Prevalence, Humans, 1112 Oncology and Carcinogenesis, Oncology & Carcinogenesis, Mortality, Cancer burden analyses, Cancer, ACUTE LYMPHOBLASTIC-LEUKEMIA, disease, Global burden, OUTCOMES, CHILDHOOD-CANCER, Incidence, Risk Factor, the GBD 2019 methodology, Disability-Adjusted Life Years, GBD 2019 Adolescent Young Adult Cancer Collaborators, CARE, Cancer control efforts, Socioeconomic Factors, Oncology, Neoplasm, Female, Young adults, Human
Abstract: Funding: J A Loureiro acknowledges support from Base Funding UIDB/00511/2020 of the LEPABE funded by national funds through the FCT/MCTES (PIDDAC) and Scientific Employment Stimulus (FCT) [CEECINST/00049/2018]. Background: In estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup with unique epidemiology, clinical care needs, and societal impact. Comprehensive estimates of the global cancer burden in adolescents and young adults (aged 15–39 years) are lacking. To address this gap, we analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, with a focus on the outcome of disability-adjusted life-years (DALYs), to inform global cancer control measures in adolescents and young adults. Methods: Using the GBD 2019 methodology, international mortality data were collected from vital registration systems, verbal autopsies, and population-based cancer registry inputs modelled with mortality-to-incidence ratios (MIRs). Incidence was computed with mortality estimates and corresponding MIRs. Prevalence estimates were calculated using modelled survival and multiplied by disability weights to obtain years lived with disability (YLDs). Years of life lost (YLLs) were calculated as age-specific cancer deaths multiplied by the standard life expectancy at the age of death. The main outcome was DALYs (the sum of YLLs and YLDs). Estimates were presented globally and by Socio-demographic Index (SDI) quintiles (countries ranked and divided into five equal SDI groups), and all estimates were presented with corresponding 95% uncertainty intervals (UIs). For this analysis, we used the age range of 15–39 years to define adolescents and young adults. Findings: There were 1·19 million (95% UI 1·11–1·28) incident cancer cases and 396 000 (370 000–425 000) deaths due to cancer among people aged 15–39 years worldwide in 2019. The highest age-standardised incidence rates occurred in high SDI (59·6 [54·5–65·7] per 100 000 person-years) and high-middle SDI countries (53·2 [48·8–57·9] per 100 000 person-years), while the highest age-standardised mortality rates were in low-middle SDI (14·2 [12·9–15·6] per 100 000 person-years) and middle SDI (13·6 [12·6–14·8] per 100 000 person-years) countries. In 2019, adolescent and young adult cancers contributed 23·5 million (21·9–25·2) DALYs to the global burden of disease, of which 2·7% (1·9–3·6) came from YLDs and 97·3% (96·4–98·1) from YLLs. Cancer was the fourth leading cause of death and tenth leading cause of DALYs in adolescents and young adults globally. Interpretation: Adolescent and young adult cancers contributed substantially to the overall adolescent and young adult disease burden globally in 2019. These results provide new insights into the distribution and magnitude of the adolescent and young adult cancer burden around the world. With notable differences observed across SDI settings, these estimates can inform global and country-level cancer control efforts. Funding: Bill & Melinda Gates Foundation, American Lebanese Syrian Associated Charities, St Baldrick's Foundation, and the National Cancer Institute. publishersversion published
Published: 2022

5. Cardiovascular Risk across Glycemic Categories: Insights from a Nationwide Screening in Mongolia, 2022-2023.

Author: Batmunkh N, Enkhtugs K, Munkhbat K, Davaakhuu N, Enebish O, Dangaa B, Luvsansambuu T, Togtmol M, Bayartsogt B, Batsukh K, Tsedev-Ochir TO, Yadamsuren E, Khasag A, Unurjargal T, and Byambasukh O
Abstract: (1) Background : Diabetes mellitus is a significant risk factor for cardiovascular disease (CVD), a leading cause of death globally. Recent studies have highlighted the role of pre-diabetes, particularly impaired fasting glucose (IFG), in elevating CVD risk even before the onset of diabetes. The objective of this study was to assess cardiovascular disease (CVD) risk across specific glycemic categories, including normoglycemia, impaired fasting glucose (IFG), newly diagnosed diabetes, and long-standing diabetes, in a large Mongolian population sample. (2) Methods : This cross-sectional study utilized data from a nationwide health screening program in Mongolia between 2022 and 2023, involving 120,266 adults after applying inclusion criteria. The participants were categorized based on fasting plasma glucose levels (NGT): normoglycemia, IFG, newly diagnosed diabetes, and long-standing diabetes. CVD risk was assessed using WHO risk prediction charts, considering factors like age, blood pressure, smoking status, and diabetes status. (3) Results : CVD risk varied significantly with glycemic status. Among those with NGT, 62.9% were at low risk, while 31.2% were at moderate risk. In contrast, the IFG participants had 49.5% at low risk and 39.9% at moderate risk. Newly diagnosed diabetes showed 38.1% at low risk and 43.3% at moderate risk, while long-standing diabetes had 33.7% at low risk and 45.9% at moderate risk. Regression analysis indicated that glycemic status was independently associated with moderate to high CVD risk (OR in IFG: 1.13; 95% CI: 1.09-1.18), even after adjusting for age, gender, and central obesity. (4) Conclusions : This study emphasizes the need for early cardiovascular risk assessment and intervention, even in pre-diabetic stages like IFG.
Published: 2024
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6. Does social health insurance prevent financial hardship in Mongolia? Inpatient care: A case in point.

Author: Dorjdagva J, Batbaatar E, Svensson M, Dorjsuren B, Togtmol M, and Kauhanen J
Subjects: Catastrophic Illness economics, Delivery of Health Care economics, Family Characteristics, Health Equity economics, Hospitals, Private economics, Hospitals, Public economics, Humans, Mongolia, Patient Acceptance of Health Care statistics & numerical data, Poverty statistics & numerical data, Surveys and Questionnaires, Universal Health Insurance economics, Financial Stress economics, Financial Stress prevention & control, Health Expenditures statistics & numerical data, Hospitalization economics, Insurance, Health economics
Abstract: Background: Protecting people from financial hardship and impoverishment due to health care costs is one of the fundamental purposes of the Mongolian health system. However, the inefficient, oversized hospital sector is considered one of the main shortcomings of the system. The aim of this study is to contribute to policy discussions by estimating the extent of catastrophic health expenditure and impoverishment due to inpatient care at secondary-level and tertiary-level public hospitals and private hospitals., Methods: Data were derived from a nationally representative survey, the Household Socio-Economic Survey 2012, conducted by the National Statistical Office of Mongolia. A total of 12,685 households were involved in the study. "Catastrophic health expenditure" is defined as out-of-pocket payments for inpatient care that exceed a threshold of 40% of households' non-discretionary expenditure. The "impoverishment" effect of out-of-pocket payments for inpatient care was estimated as the difference between the poverty level before health care payments and the poverty level after these payments., Results: At the threshold of 40% of capacity to pay, 0.31%, 0.07%, and 0.02% of Mongolian households suffered financially as a result of their member(s) staying in tertiary-level and secondary-level public hospitals and private hospitals respectively. About 0.13% of the total Mongolian population was impoverished owing to out-of-pocket payments for inpatient care at tertiary-level hospitals. Out-of-pocket payments for inpatient care at secondary-level hospitals and private hospitals were responsible for 0.10% and 0.09% respectively of the total population being pushed into poverty., Conclusions: Although most inpatient care at public hospitals is covered by the social health insurance benefit package, patients who utilized inpatient care at tertiary-level public hospitals were more likely to push their households into financial hardship and poverty than the inpatients at private hospitals. Improving the hospital sector's efficiency and financial protection for inpatients would be a crucial means of attaining universal health coverage in Mongolia., Competing Interests: The authors have declared that no competing interests exist.
Published: 2021
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1. Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019

2. Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019

3. Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019

4. The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019

5. Cardiovascular Risk across Glycemic Categories: Insights from a Nationwide Screening in Mongolia, 2022-2023.

6. Does social health insurance prevent financial hardship in Mongolia? Inpatient care: A case in point.

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