607 results on '"Topisirovic, Ivan"'
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2. SMYD5 methylation of rpL40 links ribosomal output to gastric cancer
3. MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
4. Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism
5. Corrigendum
6. The mitochondrial pyruvate carrier complex potentiates the efficacy of proteasome inhibitors in multiple myeloma
7. Comparison of CX-4945 and SGC-CK2-1 as inhibitors of CSNK2 using quantitative phosphoproteomics: Triple SILAC in combination with inhibitor-resistant CSNK2
8. Mitochondrial hyperfusion via metabolic sensing of regulatory amino acids
9. Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR
10. 7SL RNA and signal recognition particle orchestrate a global cellular response to acute thermal stress.
11. Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex.
12. Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure
13. METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis
14. Regulation of gene expression via translational buffering
15. Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
16. A hydride transfer complex reprograms NAD metabolism and bypasses senescence
17. The role of GSK3 in metabolic pathway perturbations in cancer
18. Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK
19. Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth
20. Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin
21. Cancer Plasticity: The Role of mRNA Translation
22. Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways.
23. The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest
24. eLife assessment: Regulated mRNA recruitment in dinoflagellates is reflected in hyper-variable mRNA spliced leaders and novel eIF4Es
25. eLife assessment: Focal adhesion-derived liquid-liquid phase separations regulate mRNA translation
26. MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma
27. Hepatic posttranscriptional network comprised of CCR4–NOT deadenylase and FGF21 maintains systemic metabolic homeostasis
28. The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer
29. STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer
30. eLife assessment: Yeast eIF2A has a minimal role in translation initiation and uORF-mediated translational control in vivo
31. A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer
32. Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
33. Translation Links Nutrient Availability with Inflammation
34. Translational reprogramming marks adaptation to asparagine restriction in cancer
35. Cross-talk between protein synthesis, energy metabolism and autophagy in cancer
36. eIF4E Is a Central Node of an RNA Regulon That Governs Cellular Proliferation
37. elF4E Promotes Nuclear Export of Cyclin D1 mRNAs via an Element in the 3'UTR
38. MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
39. A Unique ISR Program Determines Cellular Responses to Chronic Stress
40. Cancer as an ecomolecular disease and a neoplastic consortium
41. Oncogenic Activities of IDH1/2 Mutations: From Epigenetics to Cellular Signaling
42. mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1
43. Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer
44. PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis
45. Translational control of breast cancer plasticity
46. Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathway
47. Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth
48. Translation Initiation Factors: Reprogramming Protein Synthesis in Cancer
49. Nucleus to Mitochondria: Lost in Transcription, Found in Translation
50. Biomedical Potential of mTOR Modulation by Nanoparticles
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