21 results on '"Toplu G"'
Search Results
2. Posttraumatic giant proliferating trichilemmal cysts on the parietal region of the scalp.
- Author
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Erdem H, Yildirim U, Uzunlar AK, Sahiner C, Ozcelik D, and Toplu G
- Abstract
Proliferating trichilemmal (pilar) cysts, also known as pilar tumors, are most commonly found on the scalp of elderly women. Proliferating trichilemmal cysts are rare, slowly growing, lobular masses inherited autosomal dominantly and localized on scalps, and believed to arise due to a complication of a trauma and inflammation, and 5-10% of people are reported to be effected. Herein, we present the case of a 70-year-old woman with a 23-year history of multiple enlarging scalp masses. Clinically, squamous cell carcinoma was considered in the differential diagnosis, and the lesion was totally excised. Our case emphasizes the necessity for detailed clinical and pathological correlation for differential diagnosis. [ABSTRACT FROM AUTHOR]
- Published
- 2011
3. Lefort 1 Osteotomy Study of Maxillary Bone in Caprine Skull Model: Comparison of Different Osteotomy Techniques (Piezo Versus Lindemann Bur Versus Manual Chisel).
- Author
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Serin M, Altinel D, Toplu G, Rakici IT, and Toplu SG
- Subjects
- Animals, Imaging, Three-Dimensional, Piezosurgery methods, Models, Animal, Maxilla surgery, Fractures, Comminuted surgery, Goats, Osteotomy, Le Fort methods, Tomography, X-Ray Computed
- Abstract
Objective: In this study, we aimed to compare the efficiency of different osteotomy techniques for Lefort 1 osteotomy in an experimental caprine skull model., Methods: Twelve caprine skulls were used for the study. Skulls were divided into 3 groups: (1) manual chisel group, (2) Lindemann bur group, and (3) piezo osteotomy group. Bilateral osteotomies were performed on each skull. Results were evaluated with three-dimensional computerized tomography scans and macroscopic observations of the mucosal tears and soft tissue., Results: The mean length of the bone gap in the manual, Lindemann, and piezo groups was 4.8 (±0.7), 3.38 (±1.49), and 1.39 (±0.3) mm, respectively ( P < 0.05). The mean number of comminuted fractures in the manual, Lindemann, and piezo groups was 5.5 (±1.4), 1.6 (±0.3), and 0.6 (±0.5), respectively ( P < 0.05). Mucosal tearing and soft tissue damage based on subjective inspection observations were negligible in the piezo technique. Soft tissue and mucosal damage were observed significantly more in the manual chisel osteotomy method compared with the other 2 techniques., Conclusion: We anticipate that piezo, which has started to be used in new application areas besides rhinoplasty, will continue to be used more widely, especially in reconstructive orthognathic surgery, due to the minimal damage it causes to tissues. With the long-term results, much healthier interpretations can be made., Competing Interests: The authors report no conflicts of interest., (Copyright © 2024 by Mutaz B. Habal, MD.)
- Published
- 2024
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4. Impact of Different Osteotomy Techniques on Bone Reserve in the Osteotomy Line in Sagittal Split Osteotomy: Experimental In Vitro Study in Caprine Mandible Model.
- Author
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Toplu G, Altinel D, Evin ŞG, Yiğit E, Toplu SG, and Serin M
- Subjects
- Humans, Male, Animals, Mandible diagnostic imaging, Mandible surgery, Osteotomy, Sagittal Split Ramus methods, Tomography, X-Ray Computed, Goats, Fractures, Comminuted diagnostic imaging, Fractures, Comminuted surgery
- Abstract
Objective: The objective of this study was to investigate of the effect of piezzo and conventional osteotomy techniques on bone reserve in the osteotomy line and comminuted fracture ratios that is able to compromise bone to bone contact negatively., Methods: Bilateral sagittal split ramus osteotomy was performed on 12 fresh male Thracian curly caprine mandible. In the first group (n: 12) osteotomies were performed with piezzo device. In the second group (n: 12) osteotomies were performed with micromotor and manual osteotomes. Operative time was measured. The number of comminuted fractures, length and width of the osteotomy, and the space between the osteotomy lines was evaluated from 3-dimensional computed tomography scans., Results: The mean value of procedure duration was 320.4±10.76 seconds for piezo osteotomy and 238.8±8.29 seconds for conventional micromotor ( P <0.0001). Number of comminuted fractures was 1.41±1.3 in piezoelectric group, 1.5±1.3 in conventional group and the difference was not statistically significant (p: 0,88). Osteotomy lengths and widths were 35.58±5.2, 2.196±1.9 and 36.23±5.05, 2.27±1.85 in the piezzo and conventional groups, respectively. (p lengths :0,75; p widths :0,92) The volume of the bony interface between the distal and proximal segments of the mandible after osteotomy was 166.3±184.2 mm 3 in the piezzo group and 163.5±129.3 mm 3 in the conventional group (p: 0,96)., Conclusion: The piezo surgery and the conventional osteotomy were found to be similar in terms of the gap between the distal and proximal mandible and the number of comminuted fractures. The duration to perform the conventional osteotomy was found to be shorter than the piezo surgery., Competing Interests: The authors report no conflicts of interest., (Copyright © 2023 by Mutaz B. Habal, MD.)
- Published
- 2023
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5. Postoperative Clinical and Radiological Analysis of Deviated Noses.
- Author
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Altinel D, Serin M, and Toplu G
- Subjects
- Humans, Patient Satisfaction, Treatment Outcome, Nasal Septum diagnostic imaging, Nasal Septum surgery, Nasal Septum abnormalities, Nose Deformities, Acquired diagnostic imaging, Nose Deformities, Acquired surgery, Rhinoplasty methods, Nasal Obstruction surgery
- Abstract
Background: Anatomical deformities can greatly alter nasal function, which can be largely corrected during septoplasty and septorhinoplasty operations. In this study, we aimed to objectively measure the results of septoplasty surgeries of deviated noses with radiological analysis and compare the results with clinical evaluations., Patients and Methods: Forty patients who were undergoing septorhinoplasty were included in the study. Patients were evaluated with preoperative and postoperative paranasal computed tomography scan measurements and satisfaction surveys., Results: Preoperative and postoperative mean ± SD septal deviation angle measurements were 11.9 ± 5.3 degrees and 6.5 ± 3.1 degrees, respectively. Preoperative and postoperative mean ± SD septal deviation distance measurements were 7.3 ± 4 and 3 ± 1.3 mm, respectively. Preoperative and postoperative mean ± SD oblique conchal measurement on the deviated side was 17.3 ± 3.2 and 13.4 ± 2.8, respectively. Preoperative and postoperative mean ± SD patient satisfaction survey scores were 17 ± 1.9 and 4.5 ± 1.9 points, respectively., Discussion: To obtain a nose with a greatly improved functional gains, especially in heavy deviated noses, is an important goal in septorhinoplasty surgery. It is essential to apply the technique that will benefit the patient. The most important success criterion seems to be the regression of the clinical complaints of the patients, which can be proven objectively with computed tomography scan measurements., Competing Interests: Conflicts of interest and sources of funding: none declared., (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2022
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6. Comparison of Classic Mastopexy Method with Double-Pedicled Auto-augmentation Mastopexy with Conic-Shaped Modified Inferior Butterfly Flap.
- Author
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Altınel D, Serin M, and Toplu G
- Subjects
- Cohort Studies, Esthetics, Humans, Nipples surgery, Retrospective Studies, Treatment Outcome, Mammaplasty methods, Wound Healing
- Abstract
Background: In mastopexy surgery, extra skin and a specific amount of breast tissue are resected. Resected breast tissue is not in a large amount as in reduction surgery. In this study, we have investigated the results of an auto-augmentation mastopexy technique involving use of a superior pedicled mastopexy with conic-shaped inferior butterfly flap for augmentation without implant or fat injection., Methods: A total of 80 patients, 40 patients in each group, were included in the study. In the first group, double-pedicled auto-augmentation mastopexy with conic-shaped modified inferior butterfly flap technique was used. In the second group, conventional superior pedicled wise-pattern mastopexy was utilized. The results were evaluated from photographic measurements performed from standardized preoperative and postoperative lateral photographs., Results: No major complications were seen such as partial or total areola necrosis or breast volume loss. None of our patients has made a return with request for revision surgery. Minor complication seen in several patients was resolved with early intervention. The preoperative and postoperative photographic measurements of breast projection, upper pole projection, nipple position and lower pole level from preoperative and postoperative standardized lateral photographs revealed no significant difference between the groups., Conclusion: We obtained highly satisfactory results for our patients. Following the surgery, our patients protected the cup sizes of their bra. In spite of the fact that there was no real augmentation performed in this procedure, effective straightening and the compact breast structure patients that achieved were highly successful in creating an augmented breast image., Level of Evidence Iii: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 ., (© 2022. Springer Science+Business Media, LLC, part of Springer Nature and International Society of Aesthetic Plastic Surgery.)
- Published
- 2022
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7. Prominent Ear Repair Surgery: Long-Term Results.
- Author
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Toplu G and Altinel D
- Subjects
- Adolescent, Ear, External surgery, Esthetics, Dental, Female, Humans, Male, Patient Satisfaction, Suture Techniques, Treatment Outcome, Ear Diseases, Plastic Surgery Procedures
- Abstract
Purpose: Prominent ear is common in the white population at a rate of 5%. Many surgical incision and suture techniques have been described for its correction. The purpose of this article was to report the results of the prominent ear surgeries applied in our clinic for the last 5 years and to show the details of the surgical technique, to evaluate long-term results, complications, revisions and to compare them with previously published studies., Materials and Methods: A total of 27 patients were included in the study. The patient age ranged from 7 to 60 at the time of surgery (mean age: 18.7). Of the 27 patients, 13 were female (48.2%) and 14 were male (51.8%). The procedure was bilateral in 19 cases (70.4%) and unilateral in 8 cases (29.6%). The patients were treated with the same technique by three surgeons. Aesthetic results were evaluated by patient and surgeon surveys., Results: The follow-up was between 1 and 5 years (mean: 3 years). The patients very satisfied with the overall appearance of the ears, and the symmetry of the ears was rated as excellent by all patients, parents, and surgeons., Conclusion: Regardless of the technique used, patient satisfaction appears to be high. To reduce negative results and prevent recurrence, the authors recommend that the ear is preoperatively evaluated and the treatment algorithm is used accordingly., Competing Interests: The authors report no conflicts of interest., (Copyright © 2020 by Mutaz B. Habal, MD.)
- Published
- 2021
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8. Genital Beautification and Rejuvenation with Combined Use of Surgical and Non-surgical Methods.
- Author
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Toplu G and Altinel D
- Subjects
- Esthetics, Female, Genitalia, Female, Gynecologic Surgical Procedures, Humans, Treatment Outcome, Vulva surgery, Rejuvenation, Surgery, Plastic
- Abstract
Aim: In female genital rejuvenation and beautification, interest and demand for combined surgical and non-surgical methods are increasing. This study presents the results of our labia minora reduction technique and a vulvovaginal rejuvenation and beautification concept, where a combination of fat injection into the mons pubis and labia majora, if necessary, combined with fractional carbon dioxide (CO
2 ) laser is used., Patients and Methods: Genital rejuvenation and beautification were performed on 37 patients between January 2014 and January 2019. Postoperative follow-up for 1 year to obtain data on the satisfaction of surgical and non-surgical procedures was performed., Results: Of the 37 female patients included in the study, 33 (94.5%) were satisfied or very satisfied with their postoperative appearance. Thirty (80%) patients were satisfied or very satisfied with functional results., Conclusion: The described genital beautification and rejuvenation technique combines different aesthetic female genital surgery techniques and non-surgical noninvasive procedures. These procedures, like other plastic surgeries and procedures, are designed for the subjective improvement of the patients' appearance and feelings., Level of Evidence Iv: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .- Published
- 2021
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9. Correction to: Genital Beautification and Rejuvenation with Combined Use of Surgical and Non-surgical Methods.
- Author
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Toplu G and Altinel D
- Published
- 2021
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10. Evaluation of Factors Related to Postoperative Complications in Patients Who Underwent Reduction Mammoplasty.
- Author
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Toplu G, Altınel D, and Serin M
- Abstract
Objective: This study aimed to investigate whether there was an increase in the number of postoperative complications in patients undergoing reduction mammoplasty depending on the technique used (i.e., pedicle type, skin incision pattern), existence of concomitant diseases, and presence of other risk factors., Materials and Methods: A total of 186 patients who underwent breast reduction between 2013 and 2018 (bilateral, n = 170; unilateral, n = 16) were included in the study. A retrospective review of the data of patients who underwent reduction mammoplasty, which was performed by the same surgical team in a single institution over a 6-year period, was carried out. Superomedial, superior, and inferior pedicles were used in 99, 55, and 32 patients, respectively. The median follow-up period was 4 years., Results: The median patient age was 45 (range: 16-75) years. The median total reduction weight was 2,194 (range: 80-4,800) grams. The median distance between the sternal notch and nipple was 31 cm (range: 24-45 cm) for the right breast and 30 cm (range: 22-45 cm) for the left breast. The overall complication rate was 6.9%. The complication rates in patients with and without any concomitant diseases were 10.2% and 4.6%, respectively. The overall complication rate was significantly higher in patients with smoking habit, accessory breasts, progesterone use, cerebrovascular disease, morbid obesity (Body Mass Index ≥40 kg/m
2 ), and thalassemia., Conclusion: Our analysis shows that the presence of concomitant diseases increases the risk for postoperative complications in patients who underwent reduction mammoplasty. Our findings do not suggest that any of the techniques have significant superiority to each other in terms of pedicle safety and overall complication rate., Competing Interests: Conflict of Interest: The authors declare that they have no conflicts of interest to disclose., (©Copyright 2021 by Turkish Federation of Breast Diseases Associations.)- Published
- 2021
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11. Patient reported vaginal laxity, sexual function and stress incontinence improvement following vaginal rejuvenation with fractional carbon dioxide laser.
- Author
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Toplu G, Serin M, Unveren T, and Altinel D
- Subjects
- Female, Humans, Middle Aged, Patient Satisfaction, Pruritus surgery, Surveys and Questionnaires, Atrophy surgery, Dyspareunia surgery, Lasers, Gas, Urinary Incontinence, Stress surgery, Vagina surgery
- Abstract
In this study, we have evaluated the efficiency of fractional carbon dioxide laser in the treatment of vaginal laxity and urinary incontinence. Thirty patients with vaginal laxity, sexual dysfunction and urinary incontinence complaints were treated with fractional carbon dioxide laser. Results were evaluated with patient questionnaires relating to comfort during the procedure and general satisfaction following the procedure. In the survey regarding comfort during the procedure, 90% ( n :27) of the patients reported that they were comfortable during the procedure. The survey on the level of general satisfaction six months following the procedure revealed high-moderate level of satisfaction in 86% ( n :26) of the patients. 66% ( n :20) of the patients reported improved vaginal tightness and 63% ( n :19) of the patients reported improvement in the quality of their sexual activity. Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire(PISQ-12) scores six months following the procedure were not significantly different when compared to the scores prior to the procedure. The average of Questionnaire for Urinary Incontinence Diagnosis(QUID) score prior to the procedure and six months following the procedure was 7.5 and 0.9 respectively ( p < 0.05). Fractional carbon dioxide laser treatment results in high level of satisfaction and improvement in vaginal laxity, sexual dysfunction and urinary incontinence symptoms in patients with genitourinary syndrome.
- Published
- 2021
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12. Comparison of peripheral nerve repair using ethyl-cyanoacrylate and conventional suture technique in a rat sciatic nerve injury model.
- Author
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Atam C, Orhan Z, Toplu G, Serin M, Karaduman ZO, and Öztürk A
- Subjects
- Animals, Electromyography methods, Male, Nerve Regeneration, Peripheral Nerve Injuries diagnosis, Rats, Rats, Wistar, Suture Techniques, Tissue Adhesives pharmacology, Treatment Outcome, Cyanoacrylates pharmacology, Neurosurgical Procedures methods, Peripheral Nerve Injuries surgery, Sciatic Nerve injuries, Sciatic Nerve surgery, Sutureless Surgical Procedures methods
- Abstract
Objective: The aim of this study was to compare the outcomes of primary nerve repair using either ethyl-cyanoacrylate or conventional microsuture technique in a rat peripheral nerve injury model., Methods: In this study, a total of 30 Wistar Albino rats weighing between 220 and 275 g were used. The rats were randomly divided into three groups (10 in each), including one control (group 1) and two experimental groups (group 2, conventional microsuture repair; group 3, cyanoacrylate repair). In each group, the sciatic nerve was identified and transected. No further intervention was performed in group 1. The nerve was repaired using the epineural technique with a 10/0 atraumatic nylon in group 2 and synthetic cyanoacrylate adhesive in group 3. At the fifth postoperative week, needle electromyography (EMG) was performed to measure distal latency, combined muscle action potential (CMAP), and motor nerve conduction velocity (MNCV). Following the EMG recordings, animals were euthanized. Nerve samples were collected to evaluate vacuolar degeneration, fibrosis, and foreign body reaction histopathologically., Results: In the EMG analysis, mean distal latency was significantly shorter in group 1 (0.85±0.09 ms) than in groups 2 (1.17±0.25 ms) (p=0.0052) and 3 (1.14±0.14 ms) (p=0.0026) while no significant differences existed between groups 2 and 3 (p>0.9999). The mean CMAP was greater in group 1 (10.5±0.35 mV) than in groups 2 (2.86±1.28 mV) (p=0.011) and 3 (2.16±1.34 mV) (p=0.0002), but there was no significant difference between groups 2 and 3 (p>0.9999). The mean MNCV was 53.5±5.95, 39.62±7.31, and 39.84±4.73 mm/sec in groups 1, 2, and 3, respectively. There was a significant difference between groups 1 and 2 (p=0.0052) and between 1 and 3 (p=0.0026), but not between 2 and 3 (p>0.9999). In the histopathological evaluation, the mean vacuolar degeneration score was 0, 2.12, and 1.88 in groups 1, 2, and 3, respectively. No obvious difference was observed between groups 2 and 3 (p=0.743). The mean fibrosis score was 0, 1.62, and 1.77 in groups 1, 2, and 3, respectively. There was no significant difference between groups 2 and 3 (p=0.888). The mean foreign body reaction score was 0, 2.5, and 2.44 in groups 1, 2, and 3, respectively. No difference was present between groups 2 and 3 (p=0.743)., Conclusion: Primary nerve repair using the cyanoacrylate adhesive may provide similar electrophysiological and histopathological results as compared to the conventional microsuture repair.
- Published
- 2020
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13. The beneficial effects of subcutaneous Allium cepa injection on random flap survival in rats.
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Altınel D, Serin M, Erdem H, Biltekin B, Celikten M, Kurt Yazar S, Toplu G, and Oruc E
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- Angiography, Animals, Models, Animal, Neovascularization, Physiologic, Preoperative Care, Rats, Wistar, Graft Survival, Injections, Subcutaneous, Onions, Plant Extracts administration & dosage, Surgical Flaps blood supply
- Abstract
Random flaps are frequently used in the practice of reconstructive surgery. The aim of this experimental study was to investigate the effects of Allium cepa on random flap survival in rats. Fourteen Wistar rats were used for this experimental study. The subjects were divided into experiment and control groups. Rats in the experiment group received daily injections of A. cepa extract for 7 d before the elevation of the flaps. Following the treatment period, elevation and reinsertion of the dorsal flaps were performed. Necrotic and total flaps areas were marked and calculated 7 d after the flap elevation. Histological examinations and microangiography were performed to evaluate the results. The mean value of the proportion of necrotic flap areas to the total flap area was 25.06 and 50.6% in the A. cepa and control group, respectively ( p = .0079). In the histological examination, number of vessels identified in the dermis were 23.75 ± 0.7 and 33.75 ± 9 in the A. cepa and control group, respectively ( p = .7457). In angiographic images, vessels formations were more noticeable in the A. cepa group. We conclude that preoperative subcutaneous A. cepa injection increases dorsal flap survival in rats.
- Published
- 2019
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14. Comparison of incisional delay patterns on a rat random flap model.
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Altınel D, Serin M, Erdem H, Biltekin B, Huseyinbas O, Toplu G, and Kurt Yazar S
- Subjects
- Angiography, Animals, Models, Animal, Necrosis, Neovascularization, Physiologic, Rats, Wistar, Surgical Flaps pathology, Graft Survival, Surgical Flaps blood supply, Surgical Flaps surgery
- Abstract
One of the simplest form of surgical delay can be performed by placing an incision around the flap without undermining, prior to flap elevation. In this study, we have compared the efficiency of different patterns of skin incision to improve flap survival. Twenty-eight animals were used in four groups. Incisional delay was performed prior to flap elevation in the three experiment groups. Complete incision of the three flap edges was performed in the all experiment groups with the exception of an intact skin section on the middle 1/3rd of the bilateral edges in group 1 (bilateral skin edge preserved delay: BSEPD), of a unilateral edge in group 2 (unilateral skin edge preserved delay: USEPD) and of the superior edge in group 3 (superior skin edge preserved delay: SSEPD) without any undermining. Two weeks following the delay procedure, dorsal skin flaps were raised and reinserted back to their place. The results were evaluated with the measurement of necrotic flap area, microangiographic imaging and histological evaluation. The mean percentage of necrotic flap area to whole flap area was 16.94%, 7.54%, 23.34% and 50.6% in the BSEPD, USEPD, SSEPD and control groups, respectively. In selected microangiographic images, vessels were more prominent in the delay groups. The results of the study indicate that three sided incision with an intact skin on the superior edge is not effective in providing a sufficient delay and flap survival improvement when compared to incisions with intact skin on the unilateral and bilateral edges.
- Published
- 2019
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15. Does Periosteal Graft Combined With Platelet-Rich Plasma Enhance the Healing of Bone Defect?
- Author
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Türkseven A, Özçelik D, Çaliş M, Celik HH, Yilmaz F, Önbaş Ö, Vatansever A, and Toplu G
- Subjects
- Animals, Rabbits, Random Allocation, Bone Regeneration physiology, Bone Transplantation methods, Platelet-Rich Plasma, Zygoma injuries, Zygoma surgery
- Abstract
Introduction: This study investigated the effect of periosteal graft + platelet-rich plasma (PRP) combination on facial bone defect healing., Methods: Five-millimeter critical sized defects in zygomatic arches of 12 adult New Zealand rabbits were created. Rabbits were randomly divided into 3 groups: First group (control group): bone defects of left zygomatic arches of 6 rabbits were wrapped with a silicone tube. Second group (periosteal graft group): bone defects of left zygomatic arches of 6 rabbits were wrapped with periosteal graft. Third group (experimental group): bone defects of right zygomatic arches of 12 rabbits were wrapped with periosteal graft-PRP combination. New bone formation was evaluated at 8th and 16th weeks. One rabbit was sacrificed at 8th week. Remaining 11 rabbits were imaged with 3-dimensional computed tomography (CT) at 16th week; then, zygomatic arches were removed for micro-CT and histologic examinations., Results: Three-dimensional CT analysis at 16th week revealed no significant difference between groups regarding new bone formation (P = 0.232). Micro-CT analysis of new regenerated bone at 16th week displayed significant differences between groups 1 and 3 regarding mean bone volume (BV, mm) (P = 0.028) and mean bone mineral density (BMD, mm) (P = 0.001). There was no difference between groups 2 and 3 or between groups 1 and 2, regarding BV or BMD. Histological Bone Regeneration Scorings at 16th week displayed significant difference between groups (P = 0.015). Negative correlation between 3-dimensional CT and histologic results (r = 0.120); positive correlations between BV/BMD values in micro-CT and histologic results (r = 0.524 and r = 0.456) were found., Conclusions: By enhancing bone formation capacity of periosteal grafts, periosteal graft-PRP combination provided bone formation having more volume and density comparing with silicone tube application.
- Published
- 2018
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16. Adipose Tissue-Derived Stromal Vascular Fraction Increases Osteogenesis in an Experimental Design Zygomatic Bone Defect Model.
- Author
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Toplu G, Ozcelik D, Serin M, Erdem H, and Topacoglu AT
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- Animals, Bone Regeneration, Rats, Rats, Wistar, Wound Healing, Adipose Tissue cytology, Osteogenesis physiology, Stem Cell Transplantation, Stromal Cells transplantation, Zygoma injuries, Zygoma surgery
- Abstract
Introduction: Facial bone defects are frequently encountered problems in clinical practice. Bone grafts, flaps, and alloplastic materials are often used in their treatment. This leads to donor site morbidity and prolongation of the operation. The authors have planned this study to examine whether adipose tissue derived stromal vascular fraction (SVF) has an osteogenic effect in the critical sized membranous bone defect of the zygomatic bone., Materials and Methods: Twenty male Wistar Albino rats were used. Bilateral zygomatic arches were opened with lateral incisions. A standard 3-mm bone defect was created bilaterally on the zygomatic arches of the rats. In the experiment side, the stem cell-rich SVF that was obtained by applying centrifugal process to the adipose tissue derived from the inguinal fat pad was injected into the site of the right zygomatic arch bone defect. In the control side, left zygomatic arch was left for secondary bone healing without any treatment after a 3-mm critical bone defect was created. In the postoperative 10th (n:5) and 20th weeks (n:13), the healing areas of bone defects were assessed by a 3-dimensional tomography, and then, the rats were sacrificed and bone healing was examined histologically., Results: There were no statistically significant differences on the 10th week results. At the 20th week new bone formation amount calculated from the 3-dimensional computed tomography results was significantly higher in the experiment side (P = 0.033). In the histological examination at the 20th week, there was significantly more callus formation in the experiment side (P = 0.0112)., Discussion: Stem cells can increase the rate of bone healing by differentiating into certain tissues. It is predicted that adipose tissue-derived SVF rich with mesenchymal stem cells can increase bone healing in facial bone defects and this application could replace the use of bone grafts and flaps in clinical practice. As a result, it is concluded that adipose tissue-derived stem cells can potentiate osteogenesis and reduce the possibility of developing necrosis on the bone ends.
- Published
- 2017
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17. Transungual resection of subungual glomus tumour.
- Author
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Altinel D, Serin M, Leblebici C, and Toplu G
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- Diagnosis, Differential, Female, Glomus Tumor diagnostic imaging, Glomus Tumor surgery, Humans, Magnetic Resonance Imaging, Middle Aged, Soft Tissue Neoplasms diagnostic imaging, Soft Tissue Neoplasms surgery, Glomus Tumor diagnosis, Soft Tissue Neoplasms diagnosis, Thumb
- Abstract
Glomus tumours are benign soft tissue neoplasms. In this paper, we present a case with subungual glomus tumour. Transungual resection was performed to remove tumour. The patient was doing well 6 months after the surgery with no sign of recurrence or nail deformity., Competing Interests: Competing interests: None declared., (© BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.)
- Published
- 2017
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18. The Importance of the Trigeminal Cardiac Reflex in Rhinoplasty Surgery.
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Özçelik D, Toplu G, Türkseven A, Sezen G, and Ankarali H
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- Adolescent, Adult, Anesthetics, Local administration & dosage, Female, Humans, Male, Middle Aged, Nasal Septum innervation, Outcome Assessment, Health Care, Prilocaine administration & dosage, Prospective Studies, Young Adult, Anesthetics, Local adverse effects, Bradycardia chemically induced, Intraoperative Complications chemically induced, Prilocaine adverse effects, Reflex, Trigeminocardiac drug effects, Rhinoplasty, Trigeminal Nerve drug effects
- Abstract
Background: Trigeminocardiac reflex (TCR) consists of bradycardia or asystole along with hypotension and apnea coinciding with stimulation of the trigeminal nerve. During rhinoplasty procedures, we noticed that local anesthetic solution (LAS) application to the columellar area results in bradycardia. We planned to conduct a randomized prospective study on 47 patients undergoing rhinoplasty to demonstrate the characteristics of TCR arising from the columella., Method: Local anesthetic solution containing 2% prilocaine with 1:80,000 adrenaline was applied under standard general anesthesia protocol. In group 1 (study group, n = 24), 2 mL of LAS was applied to the columella. In group 2 (control group, n = 23), 2 mL of LAS was applied to the nasal dorsum. In group 3 (control group, n = 20), after LAS was applied to nasal dorsum in group 2, we waited for 10 minutes. Then, 2 mL of LAS was applied to the columella. Here, recordings were taken for the columella.Heart rate (HR) and blood pressure (BP) were recorded just before needle insertion (baseline level), at the time of needle insertion (NIT) to the columella or dorsum, and after the 1st, 5th, 10th, 30th, and 60th seconds., Results: Transient bradycardia (≥20% drop in HR) was observed in 33% of the patients in group 1.Decrease in HR compared to the baseline level in group 1 was significantly greater than that of groups 2 and 3 at all times (P ≤ 0.05).Systolic BP in NIT and in 60th second in group 1, only in NIT in group 2 was significantly lower than that of baseline levels (P ≤ 0.05)., Conclusions: We concluded that stimulation of a sensory branch of the trigeminal nerve in the columellar area leads to TCR under general anesthesia by eliciting clinical hypotension with a drop in systolic BP and in HR of more than 20% compared to the baseline level.Knowing the existence of a certain TCR area will be helpful to the surgeon and anesthesiologist to exercise extra vigilance and to make continuous and meticulous monitoring of the electrocardiogram, HR, and BP during which the TCR may be precipitated such as local anesthetic infiltration to the columellar area in rhinoseptoplasty operations.
- Published
- 2015
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19. Long-term objective results of proximal phalanx fracture treatment.
- Author
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Ozçelik D, Toplu G, Unveren T, Kaçağan F, and Senyuva CG
- Subjects
- Adolescent, Adult, Aged, Bone Wires, Child, Child, Preschool, Female, Finger Injuries diagnostic imaging, Finger Injuries surgery, Fractures, Bone diagnostic imaging, Fractures, Bone surgery, Humans, Male, Middle Aged, Radiography, Range of Motion, Articular, Treatment Outcome, Turkey epidemiology, Finger Injuries epidemiology, Finger Phalanges injuries, Fracture Fixation statistics & numerical data, Fractures, Bone epidemiology
- Abstract
Background: Proximal phalanx fractures are common. In this study, our preferred methods regarding the treatment of proximal phalanx fractures and their long-term objective results are presented., Methods: Between October 2001 and March 2010, in the Plastic Reconstructive and Aesthetic Surgery Department of Düzce Medical Faculty, we treated 23 patients with 32 proximal phalanx fractures. Stable fractures (n=5) were treated with splints, while unstable fractures (n=27) were stabilized with 1.0 mm percutaneous intramedullary Kirschner wires following open reduction., Results: At follow-ups, ranging from 3 months to 9 years, patients were evaluated with radiologic efficiency, range of motion (ROM), total active movements (TAM), and grip power of the digit. TAM scores of 20 fingers were perfect (≥220° for D2-5, ≥150° for D1), for 7 fingers were good (180- 220° for D2-5, 120-150° for D1), and for 5 fingers were either moderate or poor. No difference was observed between grip strength of broken fingers and that of healthy fingers. As a major complication, non-union occurred in one finger., Conclusion: We concluded that Kirschner wire fixation is a reliable and simple method of treating unstable proximal phalangeal fractures, and excellent long-term results can be obtained in suitable cases. In stable proximal phalanx fractures, splints provide sufficient treatment.
- Published
- 2011
20. Subtotal ear amputation with a very narrow pedicle: a case report and review of the literature.
- Author
-
Ozçelik D, Unveren T, and Toplu G
- Subjects
- Accidents, Traffic, Adult, Humans, Male, Treatment Outcome, Amputation, Traumatic surgery, Ear, External injuries, Ear, External surgery, Plastic Surgery Procedures methods
- Abstract
Total ear amputation is common, and management can necessitate different procedures, especially microsurgical anastomosis. Partial ear amputations supplied by narrow pedicles, however, have been reported rarely. In a subtotally amputated auricle, the chance of survival depends on the vascularization within the pedicle. In our case, the right ear of a 36-year-old male patient was subtotally amputated following a traffic accident, leaving only a 6-mm skin pedicle on the cranial side. The subtotally amputated segment was bleeding from the wound margins. The ear was reattached with primary suture without using microsurgical techniques after optimal debridement. Postoperatively, we administrated dextran 40 for 5 days to improve the microcirculation and increase blood volume and antibiotic to control the infection. No signs of edema, venous congestion or arterial insufficiency were observed immediately after the operation or subsequently. The replanted auricle healed completely with 100% survival, resulting in an essentially normal contour and appearance. This successful result without microvascular anastomoses also points out the anatomical features of the auricular vascular networks.
- Published
- 2009
21. Vertical mammaplasty for gigantomastia.
- Author
-
Ozçelik D, Unveren T, Toplu G, Bilgen F, Iskender A, and Senyuva C
- Subjects
- Female, Humans, Hypertrophy, Middle Aged, Breast pathology, Breast Diseases surgery, Mammaplasty methods
- Abstract
A 48-year-old female patient presented with gigantomastia. The sternal notch-nipple distance was 55 cm for the right breast and 50 cm for the left. Vertical mammaplasty based on the superior pedicle was performed. The resected tissue weighed 3400 g for the right breast and 2800 g for the left breast. The outcome was excellent with respect to symmetry, shape, size, residual scars, and sensitivity of the nipple-areola complex. Longer pedicles or larger resections were not found in the literature on vertical mammaplasty applications. In our opinion, by using the vertical mammaplasty technique in gigantomastia it is possible to achieve a well-projecting shape and preserve NAC sensitivity.
- Published
- 2009
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