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26 results on '"Toribara, Neil W."'

6. Contributors

Author

Achem, Sami R., primary, Agrawal, Amit, additional, Altschuler, Scott E., additional, Amoo, Francis, additional, Antillon, Mainor R., additional, Bachinski, Matthew B.Z., additional, Bacon, Bruce R., additional, Barkin, Jamie S., additional, Bean, David W., additional, Boger, Major John, additional, Brzezinski, Aaron, additional, Bruno, Christine Janes, additional, Castell, Donald O., additional, Cheatham, Joseph G., additional, Cremins, James E., additional, Czaja, Albert J., additional, Davis, Dirk R., additional, Deshpande, Amar R., additional, Deutsch, John C., additional, DiPalma, Jack A., additional, Ergun, Gulchin A., additional, Fernandez, Henrique J., additional, Fitzpatrick, James E., additional, Fox, Michael G., additional, Franklin, Kevin J., additional, Freeman, Stephen R., additional, Ginsberg, Gregory G., additional, Goff, John S., additional, Gross, Seth A., additional, Guarner, Carlos, additional, Harrison, Stephen A., additional, Herrera, Jorge L., additional, Holtzmuller, Kent C., additional, Colonel J, Lieutenant, additional, Horwhat, David, additional, Hunt, Jeffrey, additional, James, David S., additional, Jones, David P., additional, Kaliney, Ryan W., additional, Kantsevoy, Sergey V., additional, Ko, Cynthia W., additional, Kondo, Kimi L., additional, Korelitz, Burton I., additional, Krier, Michael J., additional, Ku, Miranda Yeh, additional, Kugelmas, Marcelo, additional, Laird, Stephen P., additional, Lanza, Frank L., additional, LaPorta, Anthony J., additional, LaRusso, Nicholas F., additional, Lashner, Brett A., additional, Lee, Randall E., additional, Lee, Sum P., additional, McCarter, Martin D., additional, McNally, Peter R., additional, Mehdikhani, Edgar, additional, Meier, John H., additional, Muslu, Halim, additional, Padussis, James C., additional, Pais, Wilson P., additional, Pappas, Theodore N., additional, Partington, Cyrus W., additional, Pasricha, Pankaj Jay, additional, Peura, David A., additional, Prok, Lori D., additional, Quallick, Matthew R., additional, Rajapakse, Ramona O., additional, Rak, Kevin M., additional, Roberson, Erica N., additional, Roberts, Ingram M., additional, Rogers, Arvey I., additional, Rose, Suzanne, additional, Rothchild, Kevin B., additional, Runyon, Bruce A., additional, Russ, Paul D., additional, Russo, Mark W., additional, Rutland, Travis J., additional, Sampliner, Richard E., additional, Sauerwein, Tom J., additional, Schiller, Lawrence R., additional, Schoen, Jonathan A., additional, Shah, Raj J., additional, Sherman, Kenneth E., additional, Shrestha, Roshan, additional, Sjögren, Maria H., additional, Smallfield, George B., additional, Song, Major Won, additional, Springer, Erik, additional, Stengel, Joel Z., additional, Stephens, Janet K., additional, Subber, Stephen W., additional, Surawicz, Christine M., additional, Talwalker, Jayant A., additional, Tayal, Shalini, additional, Tennyson, Christina A., additional, Thirumurthi, Selvi, additional, Tiedeken, John J., additional, Toribara, Neil W., additional, Torres, Dawn McDowell, additional, Triadafilopoulos, George, additional, Trotter, James F., additional, Vakil, Nimish, additional, Wald, Arnold, additional, Walter, Michael H., additional, Warren, George H., additional, Watanabe, Jill M., additional, West, Sterling G., additional, Wilcox, C. Mel, additional, Zeligman, Bernard E., additional, Zetterman, Rowen K., additional, and Zhao, Di, additional

Published
2010
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8. Screening for colorectal cancer

Author

Toribara, Neil W. and Sleisenger, Marvin H.

Subjects
Colorectal cancer -- Diagnosis, Medical screening -- Evaluation, Intestinal polyps -- Health aspects
Abstract

Screening people at high risk for colorectal cancer and removing any colorectal polyps found could substantially reduce the incidence and mortality of the disease. Colorectal cancer is the second leading cause of death from cancer in the US. There is extensive evidence that colorectal cancer develops from colorectal polyps, and researchers with the National Polyp Study found that the incidence of colorectal cancer can be reduced 90% by surgically removing all colorectal polyps. Several gene defects have been found to be associated with colorectal cancer. Individuals with the gene defect or a family history of colorectal cancer should be screened periodically. Fecal blood testing is commonly used, but several studies have not been able to demonstrate that it reduces mortality. Flexible sigmoidoscopy is effective, but it can not examine the entire colon. Colonoscopy remains the diagnostic method of choice for detecting and removing colorectal polyps.

Published
1995

11. Colorectal cancer: a new look at an old problem

Author

Toribara, Neil W.

Subjects
Colorectal cancer -- Care and treatment, Health, Care and treatment
Abstract

This discussion was selected from the weekly staff conferences in the Department of Medicine, University of California, San Francisco. Taken from a transcription, it has been edited by Nathan M. Bass, MD, PhD, Associated Professor of Medicine, under the direction of Lloyd H. Smith Jr, MD, Professor of Medicine and Associate Dean in the School of Medicine., Homer A. Bousshey, MDW(*): Colorectal cancer is a highly prevalent health problem. The combined factors of a long natural history, familial susceptibility, and endoscopic accessibility of this malignant disorder and [...]

Published
1994

16. Hereditary nonpolyposis colorectal cancer in young colorectal cancer patients: High-risk clinic versus population-based registry

Author

Terdiman, Jonathan P., primary, Levin, Theodore R., additional, Allen, Brian A., additional, Gum, James R., additional, Fishbach, Andrea, additional, Conrad, Peggy G., additional, Miller, Glenn A., additional, Weinberg, Vivian, additional, Bachman, Ronald, additional, Bergoffen, Joann, additional, Stembridge, Ann, additional, Toribara, Neil W., additional, Sleisenger, Marvin H., additional, and Kim, Young S., additional

Published
2002
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19. Mucin Genes Expressed by Human Female Reproductive Tract Epithelia1

Author

Gipson, Ilene K., primary, Ho, Samuel B., additional, Spurr-Michaud, Sandra J., additional, Tisdale, Ann S., additional, Zhan, Qian, additional, Torlakovic, Emina, additional, Pudney, Jeffrey, additional, Anderson, Deborah J., additional, Toribara, Neil W., additional, and Hill, Joseph A., additional

Published
1997
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22. Biochemical and Other Markers of Colon Cancer

Author

Ho, Samuel B., Toribara, Neil W., Bresalier, Robert S., and Kim, Young S.

Abstract

Advances in the understanding of biochemical and molecular processes associated with cellular growth and differentiation, as well as colonic carcinogenesis hold promise for the development of new diagnostic and therapeutic modalities for this disease. Altered glycosylation of cell surface and secreted glycoconjugates appear to be useful markers in differentiating normal from malignant colonic tissue. New information regarding deletion and inappropriate expression of several blood group-related carbohydrate antigens as well as the synthesis of unique cancer-related carbohydrate structures has been derived from the use of monoclonal antibody technology, and may lead to more sensitive and specific screening tests and targeted therapies. Several glycoprotein markers for colon cancer have been studied whose diagnostic accuracy may surpass the limited sensitivity and specificity of traditional markers such as CEA. Colorectal cancers contain numerous quantitative and qualitative differences in metabolic and synthetic enzyme activities compared with normal colonic mucosa, which may be of potential importance in designing chemotherapeutic regimens or for following disease activity. Other cancer-associated markers, such as increases in orthinine decarboxylase activity and crypt cell labeling reflect abnormal proliferative activity and may be correlated with premalignant states. Studies of protooncogene expression and certain chromosomal deletions will provide insight into mechanisms of carcinogenesis and may also serve to define high-risk individuals.

Published
1988
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23. Localization of mucin (MUC2and MUC3) messenger RNA and peptide expression in human normal intestine and colon cancer

Author

Chang, Sae-Kyung, Dohrman, Austin F., Basbaum, Carol B., Ho, Samuel B., Tsuda, Tohru, Toribara, Neil W., Gum, James R., and Kim, Young S.

Abstract

Background/Aims:Several studies have reported Northern blot data showing that mucin is expressed in a tissue-specific manner. To determine whether expression is limited to specific cell types within these tissues requires histological analysis. Methods:Both immunocytochemistry and in situ hybridization were used to identify cell types expressing the MUC2and MUC3mucins in the human small intestine, colon, and colon carcinoma. Results:In the normal small intestine and colon, an antibody recognizing the MUC2apomucin stained goblet cells. In contrast, an antibody recognizing the MUC3apomucin stained both goblet and absorptive cells. Consistent with this, in situ hybridization showed MUC2messenger RNA (mRNA) only in goblet cells and MUC3mRNA in both goblet and absorptive cells. In several samples of moderately well-differentiated colon cancer, MUC2and MUC3showed distinct patterns of expression, but the expression level of each was reduced compared with levels in normal tissue; there was considerable tumor-to-tumor and cell-to-cell variability using both mucin antibodies and complementary DNA probes. Conclusions:Individual mucin genes have distinct patterns of expression within mucin-producing tissues, suggesting that the various mucin gene products play distinct functional roles.

Published
1994
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26. Contributors

Author

Achem, Sami R., Agrawal, Amit, Altschuler, Scott E., Amoo, Francis, Antillon, Mainor R., Bachinski, Matthew B.Z., Bacon, Bruce R., Barkin, Jamie S., Bean, David W., Jr, Boger, Major John, Brzezinski, Aaron, Bruno, Christine Janes, Castell, Donald O., Cheatham, Joseph G., Cremins, James E., Czaja, Albert J., Davis, Dirk R., Deshpande, Amar R., Deutsch, John C., DiPalma, Jack A., Ergun, Gulchin A., Fernandez, Henrique J., Fitzpatrick, James E., Fox, Michael G., Franklin, Kevin J., Freeman, Stephen R., Ginsberg, Gregory G., Goff, John S., Gross, Seth A., Guarner, Carlos, Harrison, Stephen A., Herrera, Jorge L., Holtzmuller, Kent C., Colonel J, Lieutenant, Horwhat, David, Hunt, Jeffrey, James, David S., Jones, David P., Kaliney, Ryan W., Kantsevoy, Sergey V., Ko, Cynthia W., Kondo, Kimi L., Korelitz, Burton I., Krier, Michael J., Ku, Miranda Yeh, Kugelmas, Marcelo, Laird, Stephen P., Lanza, Frank L., LaPorta, Anthony J., LaRusso, Nicholas F., Lashner, Brett A., Lee, Randall E., Lee, Sum P., McCarter, Martin D., McNally, Peter R., Mehdikhani, Edgar, Meier, John H., Muslu, Halim, Padussis, James C., Pais, Wilson P., Pappas, Theodore N., Partington, Cyrus W., Pasricha, Pankaj Jay, Peura, David A., Prok, Lori D., Quallick, Matthew R., Rajapakse, Ramona O., Rak, Kevin M., Roberson, Erica N., Roberts, Ingram M., Rogers, Arvey I., Rose, Suzanne, Rothchild, Kevin B., Runyon, Bruce A., Russ, Paul D., Russo, Mark W., Rutland, Travis J., Sampliner, Richard E., Sauerwein, Tom J., Schiller, Lawrence R., Schoen, Jonathan A., Shah, Raj J., Sherman, Kenneth E., Shrestha, Roshan, Sjögren, Maria H., Smallfield, George B., III, Song, Major Won, Springer, Erik, Stengel, Joel Z., Stephens, Janet K., Subber, Stephen W., Surawicz, Christine M., Talwalker, Jayant A., Tayal, Shalini, Tennyson, Christina A., Thirumurthi, Selvi, Tiedeken, John J., Toribara, Neil W., Torres, Dawn McDowell, Triadafilopoulos, George, Trotter, James F., Vakil, Nimish, Wald, Arnold, Walter, Michael H., Warren, George H., Watanabe, Jill M., West, Sterling G., Wilcox, C. Mel, Zeligman, Bernard E., Zetterman, Rowen K., and Zhao, Di

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