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3. Bilateral pigmented retinopathy following measles: long-term follow-up and possible association with keratoconus

Author

G. Delvecchio, Torlai F, and Peduzzi M

Subjects
Bilateral pigmented retinopathy, Adult, Male, Keratoconus, medicine.medical_specialty, genetic structures, keratoconus, Fundus Oculi, Visual Acuity, Fundus (eye), Pallor, Ophthalmoscopy, 03 medical and health sciences, Amaurosis, 0302 clinical medicine, Atrophy, Ophthalmology, medicine, Humans, Longitudinal Studies, Fluorescein Angiography, medicine.diagnostic_test, business.industry, General Medicine, medicine.disease, eye diseases, Surgery, medicine.anatomical_structure, 030221 ophthalmology & optometry, sense organs, medicine.symptom, business, 030217 neurology & neurosurgery, Retinitis Pigmentosa, Retinopathy, Optic disc, Follow-Up Studies, Measles
Abstract

A case of pigmentary retinopathy following measles is presented with follow-up of 24 years. A 29-year-old man complained of almost complete blindness during measles infection at the age of 5 (1966). Ophthalmoscopy revealed retinal edema with pallor of the optic disc and in a few months pigment alterations gave the fundus a salt-and-pepper appearance. In 1974 and 1985 a pigmentary retinopathy was present with optic atrophy and typical bone corpuscle deposits, and marked impairment of visual function. In 1990 (i.e. 24 years after the onset of symptoms) the fundus shows pigmentary degeneration with optic atrophy and narrowed vessels, ERG is extinguished and visual fields and dark adaptation cannot be recorded owing to amaurosis. The patient also present bilateral keratoconus. The possible association between these two entities, which to our knowledge has not been previously reported, is discussed.

Published
1991

5. [Blood viscosity and erythrocyte deformability in diabetic retinopathy].

Author

Melli M, Poggi M, Codeluppi L, Baraldi P, Torlai F, and Peduzzi M

Subjects
Adult, Aged, Diabetes Mellitus, Type 1 blood, Diabetes Mellitus, Type 2 blood, Female, Fibrinogen analysis, Hematocrit, Humans, Male, Middle Aged, Blood Viscosity, Diabetic Retinopathy blood, Erythrocytes physiology
Abstract

The whole blood and plasma viscosity, hematocrit and plasma fibrinogen were studied in 26 diabetic patients (11 with and 15 without retinopathy) and in 25 non-diabetic control subjects. Blood viscosity, plasma viscosity and plasma fibrinogen were significantly higher in diabetics than in controls, but no significant differences were found when diabetics with retinopathy were compared to diabetics without retinopathy. The red cell deformability was significantly reduced in diabetics if compared with that of controls; the statistical significance of this reduction was confirmed only in the group of diabetics with retinopathy, but failed when the group of diabetics without retinopathy was considered.

Published
1983

6. Familial pseudotumor cerebri in male heterozygous twins.

Author

Torlai F, Galassi G, Debbia A, Crisi G, and Peduzzi M

Subjects
Heterozygote, Humans, Male, Middle Aged, Pseudotumor Cerebri cerebrospinal fluid, Pseudotumor Cerebri physiopathology, Diseases in Twins, Pseudotumor Cerebri genetics
Abstract

Papilledema due to raised intracranial pressure in absence of intracranial mass arose roughly at the same time in 2 male heterozygous twins. The diagnosis of benign intracranial hypertension (BIH) was confirmed by the finding of normal cerebrospinal fluid and high opening pressure. Neurologic examination was normal. In both cases choroidal folds were evident. The relationship between BIH and genetic factors is discussed.

Published
1989
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