82 results on '"Tormos Muñoz, Josep M."'
Search Results
2. Lifestyle trajectories in middle-aged adults and their relationship with health indicators
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Roca-Ventura, Alba, primary, Solana-Sánchez, Javier, additional, Cattaneo, Gabriele, additional, Tormos-Muñoz, Josep M., additional, Pascual-Leone, Álvaro, additional, and Bartrés-Faz, David, additional
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- 2024
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3. Impact of repetitive negative thinking on subjective cognitive decline: insights into cognition and brain structure.
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Mulet-Pons, Lídia, Solé-Padullés, Cristina, Cabello-Toscano, María, Abellaneda-Pérez, Kilian, Perellón-Alfonso, Ruben, Cattaneo, Gabriele, Sánchez, Javier Solana, Alviarez-Schulze, Vanessa, Bargalló, Nuria, Tormos-Muñoz, Josep M., Pascual-Leone, Alvaro, Bartrés-Faz, David, and Vaqué-Alcázar, Lídia
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BRAIN anatomy ,PESSIMISM ,CROSS-sectional method ,RESEARCH funding ,BLOOD-brain barrier ,QUESTIONNAIRES ,KRUSKAL-Wallis Test ,DESCRIPTIVE statistics ,MANN Whitney U Test ,EXPERIENCE ,COGNITION disorders ,DATA analysis software ,CONFIDENCE intervals ,COGNITION ,MIDDLE age ,OLD age - Abstract
Introduction: Individuals with subjective cognitive decline (SCD) express concern about self-perceived cognitive decline despite no objective impairment and are at higher risk of developing Alzheimer's disease. Despite documented links between SCD and repetitive negative thinking (RNT), the specific impact of RNT on brain integrity and cognition in exacerbating the SCD condition remains unclear. We aimed to investigate the influence of RNT on global cognition and brain integrity, and their interrelationships among healthy middle-aged and older adults experiencing SCD. Methods: Out of 616 individuals with neuroimaging and neuropsychological data available, 89 (mean age = 56.18 years; 68.54% females) met SCD criteria. Eighty-nine non-SCD individuals matched by age, sex, and education were also selected and represented the control group (mean age = 56.09 years; 68.54% females). Global cognition was measured using the preclinical Alzheimer's cognitive composite (PACC5), which includes dementia screening, episodic memory, processing speed, and category fluency tests. RNT was calculated through three questionnaires assessing intrusive thoughts, persistent worry, and rumination. We generated cortical thickness (CTh) maps and quantified the volume of white matter lesions (WML) in the whole brain, as grey and white matter integrity measures, respectively. Results: SCD individuals exhibited higher RNT scores, and thinner right temporal cortex compared to controls. No differences were observed in PACC5 and WML burden between groups. Only the SCD group demonstrated positive associations in the CTh-PACC5, CTh-RNT, and WML-RNT relationships. Discussion: In this cross-sectional study, RNT was exclusively associated with brain integrity in SCD. Even though our findings align with the broader importance of investigating treatable psychological factors in SCD, further research may reveal a modulatory effect of RNT on the relationship between cognition and brain integrity in SCD. [ABSTRACT FROM AUTHOR]
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- 2024
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4. “Guttmann Cognitest®,” a digital solution for assessing cognitive performance in adult population: A feasibility and usability pilot study
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Roca-Ventura, Alba, primary, Solana-Sánchez, Javier, additional, Heras, Eva, additional, Anglada, Maria, additional, Missé, Jan, additional, Ulloa, Encarnació, additional, García-Molina, Alberto, additional, Opisso, Eloy, additional, Bartrés-Faz, David, additional, Pascual-Leone, Alvaro, additional, Tormos-Muñoz, Josep M., additional, and Cattaneo, Gabriele, additional
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- 2024
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5. "Guttmann Cognitest ® ," a digital solution for assessing cognitive performance in adult population: A feasibility and usability pilot study.
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Roca-Ventura, Alba, Solana-Sánchez, Javier, Heras, Eva, Anglada, Maria, Missé, Jan, Ulloa, Encarnació, García-Molina, Alberto, Opisso, Eloy, Bartrés-Faz, David, Pascual-Leone, Alvaro, Tormos-Muñoz, Josep M., and Cattaneo, Gabriele
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- 2024
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6. “Guttmann Cognitest”®, preliminary validation of a digital solution to test cognitive performance
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Cattaneo, Gabriele, primary, Pachón-García, Catherine, additional, Roca, Alba, additional, Alviarez-Schulze, Vanessa, additional, Opisso, Eloy, additional, García-Molina, Alberto, additional, Bartrés-Faz, David, additional, Pascual-Leone, Alvaro, additional, Tormos-Muñoz, Josep M., additional, and Solana-Sánchez, Javier, additional
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- 2022
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7. Neural signatures of meaning in life dimensions and its contribution to self‐perceived cognition in middle‐aged individuals
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Abellaneda‐Pérez, Kilian, primary, Cattaneo, Gabriele, additional, Cabello‐Toscano, María R, additional, Vaqué‐Alcázar, Lídia, additional, Solana, Javier, additional, Mulet‐Pons, Lídia, additional, Bargalló, Núria, additional, Tormos‐Muñoz, Josep M, additional, Pascual‐Leone, Alvaro, additional, and Bartrés‐Faz, David, additional
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- 2021
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8. TMS‐induced EEG perturbation as a marker of psychological resilience to deleterious mental health effects during the COVID‐19 pandemic
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Perellón‐Alfonso, Ruben, primary, Redondo‐Camós, María, additional, Abellaneda‐Pérez, Kilian, additional, Cattaneo, Gabriele, additional, Delgado‐Gallén, Selma, additional, España‐Irla, Goretti, additional, Sánchez, Javier Solana, additional, Tormos‐Muñoz, Josep M., additional, Pascual‐Leone, Alvaro, additional, and Bartrés‐Faz, David, additional
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- 2021
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9. Loneliness experience through COVID‐19 pandemic and lockdown is related with resting‐state brain networks functional connectivity
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Cabello‐Toscano, María R., primary, Macià, Dídac, additional, Cattaneo, Gabriele, additional, Solana, Javier, additional, Abellaneda‐Pérez, Kilian, additional, Vaqué‐Alcázar, Lídia, additional, Tormos‐Muñoz, Josep M., additional, Pascual‐Leone, Alvaro, additional, and Bartres‐Faz, David, additional
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- 2021
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10. Aging in the Digital Age: Using Technology to Increase the Reach of the Clinician Expert and Close the Gap Between Health Span and Life Span
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Gomes-Osman, Joyce, primary, Solana-Sánchéz, Javier, additional, Rogers, Emily, additional, Cattaneo, Gabriele, additional, Souillard-Mandar, William, additional, Bates, David, additional, Gomez, Enrique J., additional, Tormos-Muñoz, Josep M., additional, Bartrés-Faz, David, additional, and Pascual-Leone, Álvaro, additional
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- 2021
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11. Aging in the Digital Age : Using Technology to Increase the Reach of the Clinician Expert and Close the Gap Between Health Span and Life Span
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Gomes-Osman, Joyce, Solana-Sánchéz, Javier, Rogers, Emily, Cattaneo, Gabriele, Souillard-Mandar, William, Bates, David, Gomez, Enrique J., Tormos-Muñoz, Josep M., Bartrés-Faz, David, Pascual-Leone, Álvaro, Gomes-Osman, Joyce, Solana-Sánchéz, Javier, Rogers, Emily, Cattaneo, Gabriele, Souillard-Mandar, William, Bates, David, Gomez, Enrique J., Tormos-Muñoz, Josep M., Bartrés-Faz, David, and Pascual-Leone, Álvaro
- Abstract
Altres ajuts: Fundació La Caixa (LCF/PR/PR16/11110004), Institut Guttmann i Fundació Abertis, ICREA Academia 2019 award research grants i INNOBRAIN (COMRDI15-1-0017), Age-related cognitive impairment (ARCI) has a profound impact on individuals, families, health care systems, and societies at large. Evidence suggests that ARCI is the consequence of underlying brain pathology. Therefore, efforts to minimize the impact of ARCI and thus closing the gap between health span and life span, which has widened in recent years, requires early detection and timely deployment of targeted, personalized interventions. Access to clinical experts is limited and technology screening and assessment methods are thus appealing. However, as traditionally implemented patients were deprived of the benefit of personalized connection with a clinician, which is particularly critical for the prescription and to ensure the adherence to and ultimate success of therapeutic interventions. We present the concept of Intelligent Technology Therapy Assistant (ITA) as a scalable solution that increases the reach of clinical experts while sustaining the personal connection between each patient and their clinician. We illustrate ITA with the "Guttman Neuro Personal Trainer" ®, a tele-rehabilitation platform that provides neuropsychological evaluation and care, and the Barcelona Brain Health Initiative (BBHI) multimodal intervention coaching app, a mobile-based platform that provides lifestyle coaching support in domains related to brain health. In addition, we discuss the translation of these models to a large-scale enterprise with Linus Health. To this end, we conclude with a discussion of challenges and opportunities to move the field forward.
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- 2021
12. Modifiable factors, cardiorespiratory fitness and cardiovascular risk are associated with cognitive and structural brain health in midlife: Results from the BBHI
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Morris, TP, primary, Gomes‐Osman, Joyce, additional, España‐Irla, Goretti, additional, Cattaneo, Gabriele, additional, Albu, Sergiu, additional, Solana, Javier, additional, Macià, Dídac, additional, Redondo‐Camós, María, additional, Delgado‐Gallén, Selma, additional, Alviarez‐Schulze, Vanessa, additional, Pachón‐García, Catherine, additional, Tormos‐Muñoz, Josep M, additional, Bartres‐Faz, David, additional, and Pascual‐Leone, Alvaro, additional
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- 2020
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13. Validation and Normative Data of the Spanish Version of the Face Name Associative Memory Exam (S-FNAME).
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Alviarez-Schulze, Vanessa, Cattaneo, Gabriele, Pachón-García, Catherine, Solana-Sánchez, Javier, Tormos-Muñoz, Josep M., Alegret, Montserrat, Pascual-Leone, Alvaro, and Bartrés-Faz, David
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EPISODIC memory ,REFERENCE values ,PSYCHOMETRICS ,MEMORY disorders ,MIDDLE-aged persons ,MEMORY - Abstract
Objective: The relevance of the episodic memory in the prediction of brain aging is well known. The Face Name Associative Memory Exam (FNAME) is a valued associative memory measure related to Alzheimer's disease (AD) biomarkers, such as amyloid-β deposition preclinical AD individuals. Previous validation of the Spanish version of the FNAME test (S-FNAME) provided normative data and psychometric characteristics. The study was limited to subjects attending a memory clinic and included a reduced sample with gender inequality distribution. The purpose of this study was to assess S-FNAME psychometric properties and provide normative data in a larger independent sample of cognitively healthy individuals. Method: S-FNAME was administered to 511 cognitively healthy volunteers (242 women, aged 41–65 years) participating in the Barcelona Brain Health Initiative cohort study. Results: Factor analysis supported construct validity revealing two underlying components: face-name and face-occupation and explaining 95.34% of the total variance, with satisfactory goodness of fit. Correlations between S-FNAME and Rey Auditory-Verbal Learning Test were statistically significant and confirmed its convergent validity. We also found weak correlations with non-memory tests supporting divergent validity. Women showed better scores, and S-FNAME was positively correlated with education and negatively with age. Finally, we generated normative data. Conclusions: The S-FNAME test exhibits good psychometric properties, consistent with previous findings, resulting in a valid and reliable tool to assess episodic memory in cognitively healthy middle-aged adults. It is a promising test for the early detection of subtle memory dysfunction associated with abnormal brain aging. [ABSTRACT FROM AUTHOR]
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- 2022
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14. Dispositivo de interacción y monitorización basado en unidad de medición inercial en entornos de realidad virtual para rehabilitación de la extremidad superior
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Ontiveros Ravell, J., Vázquez, A., Sánchez González, Patricia, Opisso, Eloy, López, J., Gomez Aguilera, Enrique Javier, Soriano Crespo, Ignasi, Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina ,Electrónica - Abstract
Las tecnologías de realidad virtual siguen siendo de gran interés en el área de neurorehabilitación especialmente aquellas que permiten un alto grado de inmersión de los usuarios. Sin embargo, los dispositivos comerciales no permiten a personas con dificultades motoras aprovechar el beneficio de estas tecnologías como herramientas de rehabilitación. El objetivo del presente trabajo se ha centrado en utilizar un dispositivo que fuera lo suficientemente sencillo y de bajo coste para permitir una interacción eficiente. Para el desarrollo se ha utilizado una Unidad de Medición Inercial que permite a pacientes con daño severo en la extremidad superior interactuar con el entorno de rehabilitación de realidad virtual. Como resultado del trabajo se ha realizado una prueba técnica con usuarios sanos para comprobar la fiabilidad y funcionalidad del dispositivo.
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- 2018
15. P4‐172: MEANING IN LIFE: RESILIENCE BEYOND RESERVE
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Bartrés-Faz, David, primary, Cattaneo, Gabriele, additional, Solana, Javier, additional, Tormos-Muñoz, Josep M, additional, and Pascual-Leone, Alvaro, additional
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- 2018
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16. Evaluación de la calidad de métodos extractores de características locales en imágenes de resonancia magnética cerebral
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García Novoa, Jorge, Espejo Carrizo, M. R., Rodríguez Vila, Borja, Sánchez González, P., Luna, M., Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
Las características locales de una imagen se refieren a patrones o estructuras distintivas que permiten caracterizarla. En el campo del procesamiento de las imágenes médicas juegan un papel esencial en algoritmos de registro y reconstrucción 3D de órganos y estructuras anatómicas. En este trabajo de investigación se realiza un estudio comparativo entre los métodos extractores de características locales MSER, BRISK, SURF y BFDA con el objetivo de evaluar la calidad de estos métodos en imágenes de resonancia magnética cerebral. Para ello se definen las métricas de robustez, homogeneidad y rendimiento.
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- 2016
17. Diseño y validación de un sistema de evaluación de déficits de atención mediante técnicas de eye-tracking
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Solana Sánchez, Javier, García Molina, A., Lafuente, C., García, J.L., Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
El objetivo principal de este trabajo es el diseño de una herramienta que permita la evaluación y el posterior diagnóstico de déficits de atención en pacientes con Daño Cerebral Adquirido (DCA). Esta herramienta es posible gracias a técnicas de eye-tracking en una tarea de telerehabilitación en una plataforma por ordenador. Esta tarea se desarrolló con los aspectos definidos por neuropsicólogos del Institut Guttmann, y consiste en una secuencia de 30 parejas de imágenes, que pueden ser iguales o una de ellas puede tener una diferencia. El usuario deberá identificar si existe o no y responder correctamente en cada pantalla. El dispositivo eyetracking aporta información sobre la atención visual, donde mira en cada momento en la pantalla. Con los datos obtenidos de la tarea se propone un sistema de puntuación que dote a la misma de potencial diagnóstico, clasificando a los usuarios según el resultado de la ejecución. En este trabajo se presentan los resultados de la ejecución de 17 usuarios control y 6 usuarios paciente. Estos datos se han utilizado tanto para validar la tarea, como para distinguir las diferencias entre los dos grupos. También se propone un prototipo de sistema de puntuación en relación a los resultados de estos dos grupos.
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- 2016
18. Dispositivos personalizados para la monitorización e interacción con entornos virtuales en rehabilitación de la extremidad superior
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Ontiveros Ravell, J., Molina, F., Almenara Masbernat, M., Soriano Somovilla, Ignacio, Sánchez González, Patricia, Opisso, Eloy, Hernando Pérez, María Elena, Tormos Muñoz, Josep M., Medina, J., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
Este trabajo presenta una nueva propuesta en las terapias de neurorrehabilitación basándose en la aplicación de dispositivos creados a medida para la monitorización de pacientes y la interacción con contenidos virtuales. Se ha realizado una prueba de concepto en el Hospital de neurorrehabilitación Institut Guttmann con ocho pacientes, los resultados de la prueba realizada han permitido observar una buena aceptación de los dispositivos por los pacientes y han demostrado su viabilidad técnica. El objetivo final es conseguir métodos de rehabilitación más personalizados, monitorizados e intensivos.
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- 2016
19. Cognitive dispersion as a function of cognitive reserve: influence on cognition and functional connectivity in a healthy middle‐aged population.
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Mulet‐Pons, Lídia, Vaqué‐Alcázar, Lídia, Solé‐Padullés, Cristina, Cabello‐Toscano, María, Abellaneda‐Pérez, Kilian, Cattaneo, Gabriele, Sánchez, Javier Solana, Alviarez‐Schulze, Vanessa, Tormos‐Muñoz, Josep M., Pascual‐Leone, Alvaro, and Bartrés‐Faz, David
- Abstract
Background: Cognitive dispersion index (CDI), a measure of intraindividual variability across neuropsychological tests, is considered a sensitive marker of prodromic stages of Alzheimer's Disease (Halliday et al. J. Intell 2018;6(1):12). CDI has been negatively associated with cognitive reserve (CR), another factor that influences the risk of dementia (Stern et al. Alzh&Dement 2020;16(9):1305‐1311). Nevertheless, how these two elements interact with each other and are linked with cognition and brain state (e.g., functional connectivity), remains unclear. Our aim was to investigate whether CDI has a differential influence on cognitive performance (CP) and on resting‐state functional connectivity (rsFC) as a function of CR level, in a healthy middle‐aged sample. Method: Five hundred forty‐four healthy volunteers (aged 53.11±7.10 years; 269 female) from the Barcelona Brain Health Initiative cohort (BBHI, https://bbhi.cat/en), were stratified by CR (median = 14) into High CR (HCR, N = 230) and Low CR (LCR, N = 314) using the cognitive reserve questionnaire (CRQ; Rami et al. Rev Neurol 2011;52(4):195‐201). CDI was extracted by intraindividual standard deviation method (Costa et al. Clinic Neuropsychol 2019;33(2):369‐389) and CP was calculated as a global cognition composite score including episodic memory, speed of processing and executive function tests. Functional magnetic resonance imaging (fMRI) was acquired, and measures of rsFC within networks were computed through Shirer atlas (Shirer et al. Cerebral Cortex 2012;22(1):158‐165). Statistical analyses were based on univariate ANCOVA GLMs, and partial correlations adjusted by age and gender. Result: Though no significant group interaction was found, a negative correlation between CDI and CP was identified for the HCR group (r = ‐0.170,p = 0.010; Fig.1A). On fMRI there was a significant group difference (HCR vs. LCR) in the association between CDI and rsFC in anterior salience network (aSN: F = 5.005,p = 0.026), where only HCR participants showed a significant negative association between CDI and aSN rsFC values (r = ‐0.187,p = 0.010; Fig.1B&C). Conclusion: Our findings suggested that CDI has a clearly measurable effect on HCR participants, both in terms of its effect on CP and on rsFC. These results highlight the value of considering CDI measurements when performing neuropsychological assessments in middle‐aged individuals, particularly in those with high CR estimates. [ABSTRACT FROM AUTHOR]
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- 2023
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20. Kinect-based occupational therapy virtual environment for functional neurorehabilitation of the upper limb
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Molina, F., Gómez, C., Ontiveros, J., Villán Villán, M.A., Pérez, R., Martín, C., Opisso, Eloy, Medina Casanovas, J., Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Telecomunicaciones - Abstract
The use of virtual reality technologies has attracted great interest in the area of functional neurorehabilitation [1]. These technologies have a strong ludic component that can increase motivation. Furthermore, Kinect-based motion tracking enables us to individualize the exercises and to generate knowledge [2]. The aim of this research is to perform a proof of concept test of a virtual environment for upper limb rehabilitation. To this end, we have designed two rehabilitation virtual scenarios based on occupational therapy activities. Activities are monitored by a control system based on Microsoft® Kinect sensor [3], for performing bilateral hand coordination and finger dissociation rehabilitation exercises. Both virtual scenarios have been validated by expert therapists at the Institut Guttmann of Nerurrehabilitación and a preliminary evaluation has been performed with four traumatic brain injury patients.
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- 2015
21. ASSOCIATIONS BETWEEN SOCIODEMOGRAPHIC AND LIFESTYLE FACTORS WITH LONELINESS: THE ROLE OF MEANING IN LIFE
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Bartres-Faz, David, Cattaneo, Gabriele, Macià, Dídac, Solana, Javier, Tormos-Muñoz, Josep M<ce:sup loc='post">a</ce:sup>, and Pascual-Leone, Alvaro
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- 2019
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22. CareCloud: Plataforma de soporte y asistencia a cuidadores
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Moreno Sánchez, Pedro Antonio, Chausa Fernández, Paloma, García Rudolph, A., López Blázquez, R., Ceballos, Jordi, Saperas, Josep Manel, Sánchez González, Patricia, Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
El aumento de las personas con discapacidad está demandando la aparición de nuevos modelos de cuidado en los que el cuidador informal desarrolle un papel fundamental como fuente de provisión de cuidados. La falta de preparación del cuidador junto con los frecuentes episodios de estrés y depresión que sufren ante la elevada carga psicológica y laboral, tienen un impacto muy negativo tanto en la condición del cuidador como en las tareas de cuidado. Con el objetivo de mejorar los cuidados provistos y la calidad de vida de los cuidadores informales surge la plataforma CareCloud. Esta plataforma proporciona al cuidador informal servicios destinados a la provisión de contenidos personalizados de formación sobre los distintos cuidados que prestan a sus familiares. Además, permite la gestión de los cuidados a través de servicios de coordinación entre distintos cuidadores, así como procedimientos de evaluación del cuidado que permitan detectar problemas ocurridos en la asistencia prestada.
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- 2014
23. Modelling ecological cognitive rehabilitation therapies for building virtual environments in brain injury
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Martínez Moreno, Jose María, Sánchez González, Patricia, Luna Serrano, Marta, Roig, T., Tormos Muñoz, Josep M., Gómez Aguilera, Enrique J., Martínez Moreno, Jose María, Sánchez González, Patricia, Luna Serrano, Marta, Roig, T., Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
- Abstract
Brain Injury (BI) has become one of the most common causes of neurological disability in developed countries. Cognitive disorders result in a loss of independence and patients? quality of life. Cognitive rehabilitation aims to promote patients? skills to achieve their highest degree of personal autonomy. New technologies such as virtual reality or interactive video allow developing rehabilitation therapies based on reproducible Activities of Daily Living (ADLs), increasing the ecological validity of the therapy. However, the lack of frameworks to formalize and represent the definition of this kind of therapies can be a barrier for widespread use of interactive virtual environments in clinical routine.
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- 2015
24. MEANING IN LIFE: RESILIENCE BEYOND RESERVE
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Bartrés-Faz, David, Cattaneo, Gabriele, Solana, Javier, Tormos-Muñoz, Josep M, and Pascual-Leone, Alvaro
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- 2018
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25. THE BARCELONA BRAIN HEALTH INITIATIVE: A COHORT STUDY TO EXPLORE AND PROMOTE DETERMINANTS OF BRAIN HEALTH
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Bartrés-Faz, David, Cattaneo, Gabriele, Solana, Javier, García-Nogales, Paula, Morris, Timothy P., Tormos-Muñoz, Josep M<ce:sup loc='post">a</ce:sup>, and Pascual-Leone, Alvaro
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- 2018
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26. Knowledge representation tool for cognitiveprocesses modeling
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Caballero Hernandez, Ruth, Luna Serrano, Marta, Cáceres Taladriz, César, García Molina, A., García Rudolph, A., López Blázquez, R., Toig Rovira, T., Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
In the last decades, neuropsychological theories tend to consider cognitive functions as a result of the whole brainwork and not as individual local areas of its cortex. Studies based on neuroimaging techniques have increased in the last years, promoting an exponential growth of the body of knowledge about relations between cognitive functions and brain structures [1]. However, so fast evolution make complicated to integrate them in verifiable theories and, even more, translated in to cognitive rehabilitation. The aim of this research work is to develop a cognitive process-modeling tool. The purpose of this system is, in the first term, to represent multidimensional data, from structural and functional connectivity, neuroimaging, data from lesion studies and derived data from clinical intervention [2][3]. This will allow to identify consolidated knowledge, hypothesis, experimental designs, new data from ongoing studies and emerging results from clinical interventions. In the second term, we pursuit to use Artificial Intelligence to assist in decision making allowing to advance towards evidence based and personalized treatments in cognitive rehabilitation. This work presents the knowledge base design of the knowledge representation tool. It is compound of two different taxonomies (structure and function) and a set of tags linking both taxonomies at different levels of structural and functional organization. The remainder of the abstract is organized as follows: Section 2 presents the web application used for gathering necessary information for generating the knowledge base, Section 3 describes knowledge base structure and finally Section 4 expounds reached conclusions.
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- 2013
27. Monitoring visual attention on a neurorehabilitation environment based on interactive video
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Martinez Moreno, Jose Maria, Solana Sánchez, Javier, Sanchez Carrion, R., González Palmero, S., Sánchez González, Patricia, Gómez Pérez, C., Morell Vilaseca, Marc, Cáceres Taladriz, César, Roig Rovira, Teresa, Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
The use of new technologies in neurorehabilitation has led to higher intensity rehabilitation processes, extending therapies in an economically sustainable way. Interactive Video (IV) technology allows therapists to work with virtual environments that reproduce real situations. In this way, patients deal with Activities of the Daily Living (ADL) immersed within enhanced environments [1]. These rehabilitation exercises, which focus in re-learning lost functions, will try to modulate the neural plasticity processes [2]. This research presents a system where a neurorehabilitation IV-based environment has been integrated with an eye-tracker device in order to monitor and to interact using visual attention. While patients are interacting with the neurorehabilitation environment, their visual behavior is closely related with their cognitive state, which in turn mirrors the brain damage condition suffered by them [3] [4]. Patients’ gaze data can provide knowledge on their attention focus and their cognitive state, as well as on the validity of the rehabilitation tasks proposed [5].
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- 2013
28. Brain structures identification based on feature descriptor
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Luna Serrano, Marta, Gayá Moreno, Francisco Javier, Sánchez González, Patricia, Cáceres Taladriz, César, Pascual Leone, Álvaro, Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
Traumatic Brain Injury -TBI- -1- is defined as an acute event that causes certain damage to areas of the brain. TBI may result in a significant impairment of an individuals physical, cognitive and psychosocial functioning. The main consequence of TBI is a dramatic change in the individuals daily life involving a profound disruption of the family, a loss of future income capacity and an increase of lifetime cost. One of the main challenges of TBI Neuroimaging is to develop robust automated image analysis methods to detect signatures of TBI, such as: hyper-intensity areas, changes in image contrast and in brain shape. The final goal of this research is to develop a method to identify the altered brain structures by automatically detecting landmarks on the image where signal changes and to provide comprehensive information to the clinician about them. These landmarks identify injured structures by co-registering the patient?s image with an atlas where landmarks have been previously detected. The research work has been initiated by identifying brain structures on healthy subjects to validate the proposed method. Later, this method will be used to identify modified structures on TBI imaging studies.
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- 2013
29. Clustering techniques for patients suffering acquired brain injury inneuro personal trainer
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Solana Sánchez, Javier, García Molina, A., García Rudolph, A., Cáceres Taladriz, César, Chausa Fernández, Paloma, Roig Rovira, Teresa, Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
The study of the effectiveness of the cognitive rehabilitation processes and the identification of cognitive profiles, in order to define comparable populations, is a controversial area, but concurrently it is strongly needed in order to improve therapies. There is limited evidence about cognitive rehabilitation efficacy. Many of the trials conclude that in spite of an apparent clinical good response, differences do not show statistical significance. The common feature in all these trials is heterogeneity among populations. In this situation, observational studies on very well controlled cohort of studies, together with innovative methods in knowledge extraction, could provide methodological insights for the design of more accurate comparative trials. Some correlation studies between neuropsychological tests and patients capacities have been carried out -1---2- and also correlation between tests and morphological changes in the brain -3-. The procedures efficacy depends on three main factors: the affectation profile, the scheduled tasks and the execution results. The relationship between them makes up the cognitive rehabilitation as a discipline, but its structure is not properly defined. In this work we present a clustering method used in Neuro Personal Trainer (NPT) to group patients into cognitive profiles using data mining techniques. The system uses these clusters to personalize treatments, using the patients assigned cluster to select which tasks are more suitable for its concrete needs, by comparing the results obtained in the past by patients with the same profile.
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- 2013
30. Depth sensors-based upper limb motion capture system for functional neurorehabilitation
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Molina Nájera, Fernando, Pérez Rodríguez, Rodrigo, Cáceres Taladriz, César, Tormos Muñoz, Josep M., Medina, Josep, and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
Versatile and accurate motion capture systems, with the required properties to be integrated within both clinical and domiciliary environments, would represent a significant advance in following the progress of the patients as well as in allowing the incorporation of new data exploitation and analysis methods to enhance the functional neurorehabilitation therapeutic processes. Besides, these systems would permit the later development of new applications focused on the automatization of the therapeutic tasks in order to increase the therapist/patient ratio, thus decreasing the costs [1]. However, current motion capture systems are not still ready to work within uncontrolled environments.
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- 2013
31. Dysfunctional 3D model based on structural and neuropsychological information
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Luna Serrano, Marta, Caballero Hernandez, Ruth, González Rivas, Luis Miguel, García Molina, A., García Rudolph, A., Cáceres Taladriz, César, Sanchez Carrion, R., Roig Rovira, Teresa, Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
- Subjects
Telecomunicaciones ,Medicina - Abstract
Acquired brain injury (ABI) 1-2 refers to any brain damage occurring after birth. It usually causes certain damage to portions of the brain. ABI may result in a significant impairment of an individuals physical, cognitive and/or psychosocial functioning. The main causes are traumatic brain injury (TBI), cerebrovascular accident (CVA) and brain tumors. The main consequence of ABI is a dramatic change in the individuals daily life. This change involves a disruption of the family, a loss of future income capacity and an increase of lifetime cost. One of the main challenges in neurorehabilitation is to obtain a dysfunctional profile of each patient in order to personalize the treatment. This paper proposes a system to generate a patient s dysfunctional profile by integrating theoretical, structural and neuropsychological information on a 3D brain imaging-based model. The main goal of this dysfunctional profile is to help therapists design the most suitable treatment for each patient. At the same time, the results obtained are a source of clinical evidence to improve the accuracy and quality of our rehabilitation system. Figure 1 shows the diagram of the system. This system is composed of four main modules: image-based extraction of parameters, theoretical modeling, classification and co-registration and visualization module.
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- 2013
32. Cognitive neurorehabilitation based on interactive video technology
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Martinez Moreno, Jose Maria, Solana Sánchez, Javier, Sánchez, R., González Palmero, S., Sánchez González, Patricia, Gómez Pérez, C., Morell Vilaseca, Marc, Cáceres Taladriz, César, Roig Rovira, Teresa, Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
Cognitive impairment is the main cause of disability in developed societies. New interactive technologies help therapists in neurorehabilitation in order to increase patients’ autonomy and quality of life. This work proposes Interactive Video (IV) as a technology to develop cognitive rehabilitation tasks based on Activities of Daily Living (ADL). ADL cognitive task has been developed and integrated with eye-tracking technology for task interaction and patients’ performance monitoring.
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- 2013
33. Algoritmo de control anticipatorio assisted-as-needed para neurorrehabilitación funcional de extremidad superior
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Pérez Rodríguez, Rodrigo, Costa Boned, U., Cáceres Taladriz, César, Tormos Muñoz, Josep M., Medina Casanovas, J., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
Los dispositivos robóticos se están convirtiendo en una alternativa muy extendida a las terapias de neurorrehabilitación funcional tradicionales al ofrecer una práctica más intensiva sin incrementar el tiempo empleado en la supervisión por parte de los terapeutas especialistas. Por ello, este trabajo de investigación propone un algoritmo de control anticipatorio que, bajo el paradigma 'assisted-as-needed', proporcione a una ortesis robótica las capacidades de actuación necesarias para comportarse tal y como lo haría un terapeuta que proporciona una sesión de terapia manual. Dicho algoritmo de control ha sido validado mediante un simulador robótico obteniéndose resultados que demuestran su eficacia.
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- 2012
34. Clasificación de sujetos según el control motor de la extremidad superior en Neurorrehabilitación Funcional
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Villan Villan, M.A., Pérez Rodríguez, Rodrigo, Costa Boned, U., Cáceres Taladriz, César, Tormos Muñoz, Josep M., Medina Casanovas, J., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
El presente trabajo propone la aplicación de las redes neuronales artificiales (RNA) en la comparación del movimiento de la extremidad superior entre sujetos con Daño Cerebral Adquirido y sujetos sanos. La finalidad de esta comparación es clasificar a los sujetos según su control motor para posteriormente emitir una valoración funcional del movimiento como parte de un método de evaluación objetiva en neurorrehabiliatación funcional de extremidad superior. Para realizar esta comparación se propone un método en el que se aplica un pre-procesado a los datos usando análisis de componentes principales (ACP) para reducir la dimensión de los mismos y entrenar la red. Fueron evaluadas diferentes estructuras de redes. El resultado obtenido con el método propuesto fue de un 95.65% de exactitud en la clasificación. Este resultado permite certificar el uso de las RNAs como una opción viable para la evaluación disfuncional del movimiento de sujetos sanos y con DCA. Esta investigación puede ser considerada como un estudio piloto para investigaciones en mayor profundidad que corroboren estos resultados.
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- 2012
35. Integración de tecnologías eye-tracking con vídeos interactivos para neurorrehabilitación cognitiva
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Martinez Moreno, Jose Maria, Solana Sánchez, Javier, Gómez Pérez, C., Cáceres Taladriz, César, González Palmero, S., Morell Vilaseca, Marc, Roig Rovira, Teresa, Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
La integración de las nuevas tecnologías en el proceso de rehabilitación permite la generación de terapias personalizadas, ubicuas y basadas en la evidencia. Tecnologías como el vídeo interactivo son propicias para el desarrollo de entornos virtuales en los que el paciente se ve inmerso dentro de actividades de la vida diaria en los que tiene que lograr un objetivo ecológico en un contexto seguro, controlado y adaptado a su perfil disfuncional. Dentro de este marco de rehabilitación la interacción visual paciente-entorno virtual se entiende como el mecanismo de comunicación principal, siendo además la atención visual un reflejo del estado cognitivo del paciente. El trabajo presentado en este artículo permite la integración de un sistema de eye-tracking con un entorno de neurorrehabilitación basado en vídeo interactivo. El objetivo último del sistema es la monitorización en tiempo real de la atención visual del usuario durante el proceso de neurorrehabilitación. Esta monitorización permite no sólo reproducir la ejecución de la actividad junto con el foco de la mirada, sino también detectar faltas de atención por parte del usuario, que permiten al vídeo interactivo reaccionar y adaptar la presentación de estímulos para ayudar a centrar su atención y así completar el objetivo de la actividad.
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- 2012
36. Herramienta de modelado disfuncional tridimensional basado en estudios de neuroimagen
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González Rivas, Luis Miguel, Luna Serrano, Marta, Caballero Hernandez, Ruth, Cáceres Taladriz, César, Gómez Aguilera, Enrique J., and Tormos Muñoz, Josep M.
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Informática ,Telecomunicaciones ,Medicina - Abstract
El modelado disfuncional basado en estudios de neuroimagen mejora la comprensión de los cambios estructurales provocados ante la presencia de lesiones cerebrales. Actualmente, existen numerosas herramientas para el análisis y procesado de estudios de neuroimagen. Algunas de ellas, como el 3D Slicer, BrainVoyager y el FreeSurfer permiten la creación y navegación sobre modelos tridimensionales cerebrales sin alteraciones estructurales. Sin embargo, no se han detectado herramientas que permitan modelar tridimensionalmente lesiones a partir de estudios de neuroimagen, concretamente de estudios de resonancia magnética. El objetivo de este trabajo es el diseño de una metodología que permite la creación de este tipo de modelos y su visualización y navegación.
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- 2012
37. Identificación de Oportunidades de Mejora en Procesos de Neurorrehabilitación
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Gómez Pérez, C., Caballero Hernandez, Ruth, Medina Casanovas, J., Roig Rovira, Teresa, Vidal Samsó, J., Bernabeu Guitart, M., Cáceres Taladriz, César, Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
El modelado de procesos es una técnica de gestión empresarial destinada a la mejora continua de los procesos de una organización, como base operativa y estructural de la misma. En el ámbito de la Neurorrehabilitación, crece el interés por los mapas de procesos como herramienta de comprensión, representación y análisis de los procesos clínicos. El presente trabajo se centra en la identificación de oportunidades de mejora de las actividades de rehabilitación, con el objetivo de definir nuevas estrategias de monitorización y automatización que permitan su evolución hacia el nuevo modelo de rehabilitación ubicua, personalizada y basada en la evidencia.
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- 2012
38. Modelado de Procesos de Neurorrehabilitación
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Caballero Hernandez, Ruth, Gómez Pérez, C., Cáceres Taladriz, César, García Rudolph, A., Vidal Samsó, J., Bernabeu Guitart, M., Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina ,Electrónica - Abstract
La Neurorrehabilitación es un proceso clínico que se centra en el abordaje de la alteración del sistema nervioso. Existe una enorme variabilidad tanto en la tipología como en el grado de las lesiones neurológicas, lo que la convierte en un proceso extremadamente complejo de analizar y comprender. El presente trabajo se centra en el modelado de las principales actividades que se llevan a cabo en el contexto de la Neurorrehabilitación actual con el objetivo de detectar aquellos puntos en que puedan ser mejoradas, tanto a nivel organizativo como a nivel de ejecución. Por otra parte, se trata de comprenderlas en profundidad para tratar de transformarlas posteriormente en nuevas actividades automatizadas y monitorizadas que se ajusten al nuevo paradigma de rehabilitación ubicua, personalizada y basada en la evidencia.
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- 2011
39. Minería de Datos usando Metaplasticidad Artificial en la Rehabilitación Cognitiva de Pacientes con Daño Cerebral
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Marcano Cedeño, Alexis Enrique, Chausa Fernández, Paloma, Cáceres Taladriz, César, García, Alejandro, López, Raquel, García, Alberto, Roig Rovira, Teresa, Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Informática ,Medicina - Abstract
El propósito principal de esta investigación es la aplicación de la Metaplasticidad Artificial en un Perceptrón Multicapa (AMMLP) como una herramienta de minería de datos para la predicción y extracción explícita de conocimiento del proceso de rehabilitación cognitiva en pacientes con daño cerebral adquirido. Los resultados obtenidos por el AMMLP junto con el posterior análisis de la base de datos ayudarían a los terapeutas a conocer las características de los pacientes que mejoran y los programas de rehabilitación que han seguido. Esto incrementaría el conocimiento del proceso de rehabilitación y facilitaría la elaboración de hipótesis terapéuticas permitiendo la optimización y personalización de las terapias. La evaluación del AMMLP se ha realizado con datos proporcionados por el Institut Guttmann. Los resultados del AMMLP fueron comparados con los obtenidos con una red neuronal de retropropagación y con árboles de decisión. La exactitud en la predicción obtenida por el AMMLP en la subfunción cognitiva memoria verbal-visual fue de 90.71 %, resultado muy superior a los obtenidos por los demás algoritmos.
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- 2011
40. Entornos virtuales de vídeo interactivo para neurorrehabilitación cognitiva
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Martinez Moreno, Jose Maria, Sánchez González, Patricia, Morell Vilaseca, Marc, García Rudolph, A., González Palmero, S., García Molina, A., Roig Rovira, Teresa, Cáceres Taladriz, César, Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
En pocos años, la discapacidad de origen cognitivo será uno de los principales problemas de salud. El déficit cognitivo influye en la ejecución de todas las actividades de la vida diaria. Pacientes con una afección de este tipo ven alterados su entorno social y familiar. Por todo ello, se hace imprescindible el desarrollo de programas de rehabilitación que permitan minimizar las consecuencias de las lesiones adquiridas y restituir o compensar las funciones afectadas. En la actualidad nos encontramos en un momento de cambio en las metodologías de la neurorrehabilitación, donde los entornos virtuales digitales interactivos son una fuente de innovación y una ventana terapéutica para la generación de nuevas estrategias basadas en una rehabilitación personalizada, monitorizada y ubicua, con la que lograr el máximo nivel de realización en las actividades de vida diaria. En este trabajo de investigación se plantea el uso del vídeo interactivo como medio tecnológico para realizar las terapias de rehabilitación cognitiva. Se presenta una prueba de concepto de una actividad de vida diaria y su posterior análisis por el equipo clínico del Instituí Guttmann. Los resultados preliminares apoyan su uso para alcanzar una rehabilitación basada en el nuevo paradigma.
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- 2011
41. Comparación del movimiento de alcance entre sujetos Sanos y Patológicos en Neurorrehabilitación Funcional de Extremidad Superior
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Villan Villan, M.A., Pérez Rodríguez, Rodrigo, Costa Boned, U., Gómez Pérez, C., Tormos Muñoz, Josep M., Medina Casanovas, J., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
El presente trabajo de investigación tiene como propósito principal realizar una comparación del movimiento de alcance entre sujetos aquejados de Daño Cerebral Adquirido y el correspondiente patrón de normalidad. La finalidad de esta comparación es detectar los déficits motores que permitan posteriormente emitir una valoración funcional del movimiento como parte de un método de evaluación objetiva de la función motora. La comparación del movimiento se basa en las medidas de parámetros espaciales y de similitud. En este trabajo se han utilizado modelos de movimiento de sujetos sanos en ejecuciones de Actividades de Vida Diaria (e.g. 'servir agua de una jarra'), como punto de referencia para encontrar diferencias relevantes con respecto a los datos de movimiento de cuatro pacientes bajo un proceso de Neurorrehabilitación Funcional de Extremidad Superio
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- 2011
42. Análisis comparativo de algoritmos de aprendizaje para predecir la evolución de pacientes con Daño Cerebral Adquirido
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Marcano Cedeño, Alexis Enrique, Chausa Fernández, Paloma, Cáceres Taladriz, César, García, Alejandro, López, Raquel, Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Informática ,Medicina - Abstract
ste trabajo presenta un análisis comparativo entre tres algoritmos de aprendizaje diferentes basados en Árboles de Decisión (C4.5) y Redes Neuronales Artificiales (Perceptrón Multicapa MLP y Red Neuronal de Regresión General GRNN) que han sido implementados con el objetivo de predecir los resultados de la rehabilitación cognitiva de personas con daño cerebral adquirido. En el análisis se han incluido datos demográficos del paciente, el perfil de afectación y los resultados provenientes de las tareas de rehabilitación ejecutadas por los pacientes. Los modelos han sido evaluados utilizando la base de datos del Institut Guttmann. El rendimiento de los algoritmos se midió a través del análisis de la especificidad, sensibilidad y exactitud en la precisión y el análisis de la matriz de confusión. Los resultados muestran que la implementación del C4.5 alcanzó una especificidad, sensibilidad y exactitud en la precisión del 98.43%, 83.77% y 89.42% respectivamente. El rendimiento del C4.5 fue significativamente superior al obtenido por el Perceptrón Multicapa y la Red de Regresión General.
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- 2011
43. Detección y seguimiento de objetos en vídeos de actividades de vida diaria para rehabilitación de pacientes con daño cerebral adquirido
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Luna Serrano, Marta, Sánchez González, Patricia, Bonilla Carrion, E., Fernandez Perez, Alvaro, Martinez Moreno, Jose Maria, Morell Vilaseca, Marc, Cáceres Taladriz, César, Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
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Telecomunicaciones ,Medicina - Abstract
Las técnicas de rehabilitación permiten la recuperación y mejora de las funciones dañadas o deterioradas y ayuda al paciente con DCA a adaptarse a su nueva situación. El avance tecnológico que se ha producido en las últimas décadas, ha impulsado la investigación en el diseño y desarrollo de nuevos modelos de rehabilitación. La tecnología de vídeo interactivo se convierte en un elemento de apoyo en estos nuevos modelos rehabilitadores. Se hace necesario desarrollar nuevos algoritmos de segmentación y seguimiento que permitan dotar de información adicional a los vídeos. En este trabajo se han implementado y evaluado dos métodos que permiten realizar la detección y el seguimiento de objetos de interés.
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- 2011
44. Upper Limb Motion Analysis System Based on Inertial Technology
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Pérez Rodríguez, Rodrigo, Costa, Ursula, Torrent, Marc, Solana Sánchez, Javier, Opisso, Eloy, Cáceres Taladriz, César, Tormos Muñoz, Josep M., Medina, Josep, and Gómez Aguilera, Enrique J.
- Subjects
Telecomunicaciones ,Medicina - Abstract
Here an inertial sensor-based monitoring system for measuring and analyzing upper limb movements is presented. The final goal is the integration of this motion-tracking device within a portable rehabilitation system for brain injury patients. A set of four inertial sensors mounted on a special garment worn by the patient provides the quaternions representing the patient upper limb’s orientation in space. A kinematic model is built to estimate 3D upper limb motion for accurate therapeutic evaluation. The human upper limb is represented as a kinematic chain of rigid bodies with three joints and six degrees of freedom. Validation of the system has been performed by co-registration of movements with a commercial optoelectronic tracking system. Successful results are shown that exhibit a high correlation among signals provided by both devices and obtained at the Institut Guttmann Neurorehabilitation Hospital.
- Published
- 2010
45. Data mining applied to the cognitive rehabilitation of patients with acquired brain injury
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Marcano Cedeño, Alexis Enrique, Chausa Fernández, Paloma, García, Alejandro, Cáceres Taladriz, César, Tormos Muñoz, Josep M., Gómez Aguilera, Enrique J., Marcano Cedeño, Alexis Enrique, Chausa Fernández, Paloma, García, Alejandro, Cáceres Taladriz, César, Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
- Abstract
Acquired brain injury (ABI) is one of the leading causes of death and disability in the world and is associated with high health care costs as a result of the acute treatment and long term rehabilitation involved. Different algorithms and methods have been proposed to predict the effectiveness of rehabilitation programs. In general, research has focused on predicting the overall improvement of patients with ABI. The purpose of this study is the novel application of data mining (DM) techniques to predict the outcomes of cognitive rehabilitation in patients with ABI. We generate three predictive models that allow us to obtain new knowledge to evaluate and improve the effectiveness of the cognitive rehabilitation process. Decision tree (DT), multilayer perceptron (MLP) and general regression neural network (GRNN) have been used to construct the prediction models. 10-fold cross validation was carried out in order to test the algorithms, using the Institut Guttmann Neurorehabilitation Hospital (IG) patients database. Performance of the models was tested through specificity, sensitivity and accuracy analysis and confusion matrix analysis. The experimental results obtained by DT are clearly superior with a prediction average accuracy of 90.38%, while MLP and GRRN obtained a 78.7% and 75.96%, respectively. This study allows to increase the knowledge about the contributing factors of an ABI patient recovery and to estimate treatment efficacy in individual patients.
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- 2013
46. Artificial metaplasticity prediction model for cognitive rehabilitation outcome in acquired brain injury patients
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Marcano Cedeño, Alexis Enrique, Chausa Fernández, Paloma, García, Alejandro, Cáceres Taladriz, César, Tormos Muñoz, Josep M., Gómez Aguilera, Enrique J., Marcano Cedeño, Alexis Enrique, Chausa Fernández, Paloma, García, Alejandro, Cáceres Taladriz, César, Tormos Muñoz, Josep M., and Gómez Aguilera, Enrique J.
- Abstract
Objective The main purpose of this research is the novel use of artificial metaplasticity on multilayer perceptron (AMMLP) as a data mining tool for prediction the outcome of patients with acquired brain injury (ABI) after cognitive rehabilitation. The final goal aims at increasing knowledge in the field of rehabilitation theory based on cognitive affectation. Methods and materials The data set used in this study contains records belonging to 123 ABI patients with moderate to severe cognitive affectation (according to Glasgow Coma Scale) that underwent rehabilitation at Institut Guttmann Neurorehabilitation Hospital (IG) using the tele-rehabilitation platform PREVIRNEC©. The variables included in the analysis comprise the neuropsychological initial evaluation of the patient (cognitive affectation profile), the results of the rehabilitation tasks performed by the patient in PREVIRNEC© and the outcome of the patient after a 3–5 months treatment. To achieve the treatment outcome prediction, we apply and compare three different data mining techniques: the AMMLP model, a backpropagation neural network (BPNN) and a C4.5 decision tree. Results The prediction performance of the models was measured by ten-fold cross validation and several architectures were tested. The results obtained by the AMMLP model are clearly superior, with an average predictive performance of 91.56%. BPNN and C4.5 models have a prediction average accuracy of 80.18% and 89.91% respectively. The best single AMMLP model provided a specificity of 92.38%, a sensitivity of 91.76% and a prediction accuracy of 92.07%. Conclusions The proposed prediction model presented in this study allows to increase the knowledge about the contributing factors of an ABI patient recovery and to estimate treatment efficacy in individual patients. The ability to predict treatment outcomes may provide new insights toward improving effectiveness and creating personalized therapeutic interventions based on clinical evidence.
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- 2013
47. Inverse kinematics of a 6 DoF human upper limb using ANFIS and ANN for anticipatory actuation in ADL-based physical Neurorehabilitation
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Pérez Rodríguez, Rodrigo, Marcano Cedeño, Alexis Enrique, Costa, Ursula, Solana Sánchez, Javier, Cáceres Taladriz, César, Opisso, Eloy, Tormos Muñoz, Josep M., Medina, Josep, Gómez Aguilera, Enrique J., Pérez Rodríguez, Rodrigo, Marcano Cedeño, Alexis Enrique, Costa, Ursula, Solana Sánchez, Javier, Cáceres Taladriz, César, Opisso, Eloy, Tormos Muñoz, Josep M., Medina, Josep, and Gómez Aguilera, Enrique J.
- Abstract
Objective: This research is focused in the creation and validation of a solution to the inverse kinematics problem for a 6 degrees of freedom human upper limb. This system is intended to work within a realtime dysfunctional motion prediction system that allows anticipatory actuation in physical Neurorehabilitation under the assisted-as-needed paradigm. For this purpose, a multilayer perceptron-based and an ANFIS-based solution to the inverse kinematics problem are evaluated. Materials and methods: Both the multilayer perceptron-based and the ANFIS-based inverse kinematics methods have been trained with three-dimensional Cartesian positions corresponding to the end-effector of healthy human upper limbs that execute two different activities of the daily life: "serving water from a jar" and "picking up a bottle". Validation of the proposed methodologies has been performed by a 10 fold cross-validation procedure. Results: Once trained, the systems are able to map 3D positions of the end-effector to the corresponding healthy biomechanical configurations. A high mean correlation coefficient and a low root mean squared error have been found for both the multilayer perceptron and ANFIS-based methods. Conclusions: The obtained results indicate that both systems effectively solve the inverse kinematics problem, but, due to its low computational load, crucial in real-time applications, along with its high performance, a multilayer perceptron-based solution, consisting in 3 input neurons, 1 hidden layer with 3 neurons and 6 output neurons has been considered the most appropriated for the target application.
- Published
- 2012
48. Upper Limb Portable Motion Analysis System Based on Inertial Technology for Neurorehabilitation Purpose
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Pérez Rodríguez, Rodrigo, Costa, Ursula, Torrent, Marc, Solana Sánchez, Javier, Opisso, Eloy, Cáceres Taladriz, César, Tormos Muñoz, Josep M., Medina, Josep, Gómez Aguilera, Enrique J., Pérez Rodríguez, Rodrigo, Costa, Ursula, Torrent, Marc, Solana Sánchez, Javier, Opisso, Eloy, Cáceres Taladriz, César, Tormos Muñoz, Josep M., Medina, Josep, and Gómez Aguilera, Enrique J.
- Abstract
Here an inertial sensor-based monitoring system for measuring and analyzing upper limb movements is presented. The final goal is the integration of this motion-tracking device within a portable rehabilitation system for brain injury patients. A set of four inertial sensors mounted on a special garment worn by the patient provides the quaternions representing the patient upper limb’s orientation in space. A kinematic model is built to estimate 3D upper limb motion for accurate therapeutic evaluation. The human upper limb is represented as a kinematic chain of rigid bodies with three joints and six degrees of freedom. Validation of the system has been performed by co-registration of movements with a commercial optoelectronic tracking system. Successful results are shown that exhibit a high correlation among signals provided by both devices and obtained at the Institut Guttmann Neurorehabilitation Hospital.
- Published
- 2010
49. Regular physical activity is associated with greater cortical inhibition in middle‐aged adults: Findings from Barcelona Brain Health Initiative: Prevention (nonpharmacological) / Exercise.
- Author
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España‐Irla, Goretti, Albu, Sergiu, Morris, Timothy P, Redondo‐Camós, María, Delgado‐Gallén, Selma, Cattaneo, Gabriele, Tormos‐Muñoz, Josep M, Bartrés‐Faz, David, and Pascual‐Leone, Alvaro
- Abstract
Background: Aging has been associated with changes in the mechanisms of brain plasticity, specifically with the reduction of motor cortex excitability and decreased effectiveness of mechanisms of cortical inhibition (Pascual‐Leone et al., 2011; Lissemore et al., 2018). Emerging evidence suggests that regular practice of physical activity, which can increase cardiorespiratory fitness (Sobol et al., 2016), may prevent age‐related decline in the mechanisms of brain plasticity (Gomes‐Osman et al., 2017). We therefore hypothesized that those who engage in more physical activity would have greater corticospinal excitability and more efficient cortical inhibition. Methods: Seventy‐eight healthy adults (39 women), between 41 and 65 years old were included in the study. The amount of physical activity was assessed using a self‐reported 5‐point Likert scale where 1 equalled sedentary and 5 equalled engagement in aerobic physical activity >3 hours/week. The peak respiratory oxygen uptake (VO2 peak), aerobic threshold (VT1) and anaerobic threshold (VT2) were measured by cardiopulmonary exercise test with ventilatory gas analyses. Transcranial magnetic stimulation was used to assess resting motor threshold, motor evoked potential (MEP) amplitude and long‐interval intracortical inhibition (LICI), a measure of cortical inhibition. Results: Spearman's rank correlation revealed that greater engagement in regular physical activity was associated with higher VO2 peak (ρ=.470, p =.001), VT1 (ρ=.371, p =.001) and VT2 (ρ=.414, p =.001), and higher amplitude of resting MEP (ρ=.287, p =.018). Mann‐Whitney U tests revealed higher MEP amplitude (p =.003) and more efficient LICI (p =.018) in the group who exercised >3 hours/week compared to the sedentary group. Conclusions: Regular physical activity in middle‐aged adults is related with better cardiorespiratory fitness, greater corticospinal excitability and more efficient cortical inhibitory mechanisms. [ABSTRACT FROM AUTHOR]
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- 2020
- Full Text
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50. Technologies for Monitoring Lifestyle Habits Related to Brain Health: A Systematic Review.
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Moreno-Blanco, Diego, Solana-Sánchez, Javier, Sánchez-González, Patricia, Oropesa, Ignacio, Cáceres, César, Cattaneo, Gabriele, Tormos-Muñoz, Josep M., Bartrés-Faz, David, Pascual-Leone, Álvaro, and Gómez, Enrique J.
- Subjects
META-analysis ,HABIT ,TECHNOLOGY - Abstract
Brain health refers to the preservation of brain integrity and function optimized for an individual's biological age. Several studies have demonstrated that our lifestyles habits impact our brain health and our cognitive and mental wellbeing. Monitoring such lifestyles is thus critical and mobile technologies are essential to enable such a goal. Three databases were selected to carry out the search. Then, a PRISMA and PICOTS based criteria for a more detailed review on the basis of monitoring lifestyle aspects were used to filter the publications. We identified 133 publications after removing duplicates. Fifteen were finally selected from our criteria. Many studies still use questionnaires as the only tool for monitoring and do not apply advanced analytic or AI approaches to fine-tune results. We anticipate a transformative boom in the near future developing and implementing solutions that are able to integrate, in a flexible and adaptable way, data from technologies and devices that users might already use. This will enable continuous monitoring of objective data to guide the personalized definition of lifestyle goals and data-driven coaching to offer the necessary support to ensure adherence and satisfaction. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
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