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10 results on '"Tran, Dat Quoc"'

3. Optimization of GaN Nanowires Reformation Process by Metalorganic Chemical Vapor Deposition for Device-Quality GaN Templates

Author

Delgado Carrascon, Rosalia, Tran, Dat Quoc, Sukkaew, Pitsiri, Mock, Alyssa, Ciechonski, Rafal, Ohlsson, Jonas, Zhu, Yadan, Hultin, Olof, Monemar, Bo, Paskov, Plamen, Samuelson, Lars, Darakchieva, Vanya, Delgado Carrascon, Rosalia, Tran, Dat Quoc, Sukkaew, Pitsiri, Mock, Alyssa, Ciechonski, Rafal, Ohlsson, Jonas, Zhu, Yadan, Hultin, Olof, Monemar, Bo, Paskov, Plamen, Samuelson, Lars, and Darakchieva, Vanya

Abstract

Herein, the potential of reformed GaN nanowires (NWs) fabricated by metalorganic chemical vapor deposition (MOCVD) for device-quality low-defect density templates and low-cost alternative to bulk GaN substrates is demonstrated. The effects of epilayer thickness and NW reformation conditions on the crystalline quality and thermal conductivity of the subsequent GaN epilayers are investigated. Smooth surfaces with atomically step-like morphologies with no spirals are achieved for GaN epilayers on the reformed NW templates, indicating step-flow growth mode. It is further found that annealing of the NWs at a temperature of 1030 degrees C in the presence of NH3 and H-2, followed by a coalescence done at the same temperature under planar growth conditions, leads to the most efficient screw dislocation density reduction by nearly an order of magnitude. At these optimized conditions, the growth takes place in a layer-by-layer fashion, producing a smooth surface with a root mean square (RMS) roughness of 0.12 nm. The highest thermal conductivity of k = 206 W m(-1) K-1, approaching the respective value of bulk GaN, is obtained for the optimized 2 mu m-thick GaN layer. The thermal conductivity results are further discussed in terms of the phonon-dislocation and the phonon-boundary scattering., Funding Agencies|Swedish Governmental Agency for Innovation Systems (VINNOVA) under the Competence Center Program [2016-05190]; Linkoping University; Chalmers University of Technology; ABB; Ericsson; Epiluvac; FMV; Gotmic; On Semiconductor; Saab; SweGaN; UMS; Swedish Research Council VRSwedish Research Council [2016-00889]; Swedish Foundation for Strategic ResearchSwedish Foundation for Strategic Research [FL12-0181, RIF14-055, EM16-0024]; Swedish Government Strategic Research Area in Materials Science on Functional Materials at Linkping University [2009-00971]

Published
2020
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4. Optimization of GaN Nanowires Reformation Process by Metalorganic Chemical Vapor Deposition for Device‐Quality GaN Templates

Author

Delgado Carrascon, Rosalia, primary, Tran, Dat Quoc, additional, Sukkaew, Pitsiri, additional, Mock, Alyssa, additional, Ciechonski, Rafal, additional, Ohlsson, Jonas, additional, Zhu, Yadan, additional, Hultin, Olof, additional, Monemar, Bo, additional, Paskov, Plamen P., additional, Samuelson, Lars, additional, and Darakchieva, Vanya, additional

Published
2020
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8. AB163. Microsatellite markers for preimplantation genetic diagnosis in Vietnamese DMD and hemophilia: a female carriers

Author

Tuan-Pham, Le Anh, Tran, Thinh Huy, Tran, Dat Quoc, Minh, Nguyen Thi, Huong, Nguyen Lien, Tien, Nguyen Viet, Ta, Van Thanh, Bui, The Hung, and Tran, Van Khanh

Subjects
congenital, hereditary, and neonatal diseases and abnormalities, Part 4: Oral/poster
Abstract

Microsatellite polymorphic markers were powerful tool to perform single cell diagnosis for preimplantation genetic diagnosis (PGD) in X-linked recessive disorders. This type of analysis requires haplotypes information of carrier mothers and affected sons. We present 12 Vietnamese families with duchenne muscular dystrophin (DMD) or Hemophilia A affected sons, six with each disorder. We established haplotypes based on linked microsatellite polymorphic markers in these families and performed diagnosis enabling embryo transfer from the PGD cycle. We also perform haplotypes analysis in five more families for each disease to identify more informative markers among other, in order to construct better strategy for future diagnosis. Microsatellite polymorphic markers flanking the F8 and DMD gene were used to identify haplotypes. Polar bodies (PB) were biopsied and analyzed to determine allelic association between the mutation and markers in multiplex PCR reaction. The results showed that 13 out of 28 embryos were found to be not affected by F8 or DMD gene inherited mutations and were available for transfer. Marker DXS9907, DSTR44, DSTR49 for DMD gene and marker FXS1073, DXS9897, DXS1073 for F8 gene were identified as the most frequent markers shown heterozygous alleles in mother carriers. PB analysis by microsatellite markers were proved to be useful technique for PGD of DMD and Hemophilia A families. Better strategy for PB diagnosis was built.

Published
2015

10. Genetic analysis of 55 northern Vietnamese patients with Wilson disease: seven novel mutations in ATP7B.

Author

Tuan Pham LA, Nguyen TT, Nga Le HB, Tran DQ, Ho CT, Tran TH, Ta VT, Bui TH, and Tran VK

Subjects
Adult, DNA Mutational Analysis, Exons genetics, Hepatolenticular Degeneration pathology, Humans, Male, Mutation, Sequence Analysis, DNA, Vietnam, Copper-Transporting ATPases genetics, Genetic Testing, Hepatolenticular Degeneration diagnosis, Hepatolenticular Degeneration genetics
Abstract

Wilson disease (WD) is an autosomal recessive disorder of copper metabolism. The gene responsible for WD was discovered in 1993 and is located on chromosome 13 at 13q14.3. It encodes a copper-specific transporting P-type ATPase. Early diagnosis can improve treatment outcome and decrease the rate of disability or even mortality.We used Sanger sequencing to identify mutation hot spots in 55 northern Vietnamese with a clinical diagnosis of WD. Mutations were screened and detected by direct DNA sequencing. A total of 26 different ATP7B gene mutations were identified, including seven novel mutations (five nonsense and two missense mutations). The most frequent mutations were p.Ser105Ter (24.55%), p.Arg778Leu (5.45%) and p.Thr850Ile (4.55%). Mutation detection rate in exon 2 was 34.55% and ranked first, followed by exon 8 with 16.36%, and exon 18 with 10.91% each, thus, exons 2, 8 and 18 are the mutation hot spots for northern VietnameseWD patients. These findings were different from previous studies in Asia. Our research established a suitable strategy for ATP7B gene testing in northern Vietnamese WD patients.

Published
2017
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