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7. Additional file 1 of Variation in chemical composition and antimalarial activities of two samples of Terminalia albida collected from separate sites in Guinea

Author

Camara, Aissata, Haddad, Mohamed, Traore, Mohamed Sahar, Chapeland-Leclerc, Florence, Ruprich-Robert, Gwenaël, Fourasté, Isabelle, Balde, Mamadou Aliou, Royo, Jade, Parny, Melissa, Batigne, Philippe, Salon, Marie, Coste, Agnès, Aliou Mamadou Balde, and Aubouy, Agnès

Subjects
Data_FILES
Abstract

Additional file 1:.

Published
2021
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8. Malaria in Guinean Rural Areas: Prevalence, Management, and Ethnotherapeutic Investigations in Dionfo, Sub-Prefecture of Labe

Author

Baldé, Aliou Mamadou, additional, Balde, Alpha Oumar, additional, Bah, Bilo, additional, Barry, Halimatou, additional, Traore, Saidou, additional, Bah, Fatoumata, additional, Balde, Mamadou Aliou, additional, Camara, Aissata, additional, Traore, Mohamed Sahar, additional, Balde, Elhadj Saidou, additional, Sylla, Ibrahima Kalil, additional, and Diallo, Sadou, additional

Published
2021
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9. Malaria in Guinean Rural Areas: Prevalence, Management, and Ethnotherapeutic Investigations in Dionfo, Sub-Prefecture of Labe#.

Author

Baldé, Aliou Mamadou, Balde, Alpha Oumar, Bah, Bilo, Barry, Halimatou, Traore, Saidou, Bah, Fatoumata, Balde, Mamadou Aliou, Camara, Aissata, Traore, Mohamed Sahar, Balde, Elhadj Saidou, Sylla, Ibrahima Kalil, and Diallo, Sadou

Subjects
PHYTOTHERAPY, MALARIA prevention, DRUG therapy for malaria, PROTOZOA, DRUG efficacy, EVALUATION of human services programs, RURAL conditions, POPULATION geography, TREATMENT duration, MALARIA, ETHNOLOGY research, TRADITIONAL medicine, COMMUNITY-based social services, DISEASE prevalence, ANTIMALARIALS
Abstract

As part of a validation program of antimalarial traditional recipes, an ethnotherapeutic approach was applied in Dionfo, a meso-endemic Guinean rural area where conventional health facilities are insufficient. A prevalence investigation indicated a malarial burden of 4.26%. Ethnomedical and ethnobotanical surveys led to a collection of 63 plant species used against malaria from which Terminalia albida (Combretaceae) was one of the most cited. Ethnotherapeutic evaluation of a remedy based on T. albida was applied to 9 voluntary patients suffering from uncomplicated malaria. Treatment of 7 to 14 days led to an improvement of clinical symptoms and a complete parasite clearance achievement of 8/9 patients without side effects. In addition to antiplasmodial activity in vitro and in vivo previously described, this study indicates an efficacy to support the antimalarial traditional use of T. albida , which could constitute a first-aid treatment when access to other medicines is delayed in the Dionfo community. Ethnotherapeutical investigation could be a valuable approach to guide subsequent investigations on traditional remedies. [ABSTRACT FROM AUTHOR]

Published
2021
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10. Knowledge, Attitudes and Practices of Health Care Workers on Ebola in Hospital Towards Ebola Virus Disease, Conakry, Guinea, 2016

Author

Douba Alfred, Diallo Aissatou Taran, Traore Mohamed Sahar, Touré Abdoulaye, Diallo Ibrahima Sory, Camara Alioune, Sidibe Sidikiba, Konde Mandy Kader, Guilavogui Timothé, and Bayo Mouctar

Subjects
medicine.medical_specialty, Ebola virus, business.industry, Outbreak, General Medicine, Disease, Odds ratio, medicine.disease_cause, Child health, Family medicine, Health care, medicine, Lack of knowledge, business, Good practice
Abstract

To cope with any further outbreak of Ebola Virus Disease (EVD) in Guinea, a cross-sectional study was carried out to assess the level of awareness, attitude and practice of health care workers about EVD in Conakry, Guinea. A cross-sectional study was conducted in the Institute of Nutrition and Child Health (INSE), at the national hospitals of Donka and Ignace Deen in 2016 and involved 14 clinical facilities. Scores were built up for knowledge, attitude and practice. These scores were classified into two groups: bad (score < 50%) and good (score ≥ 50%). A total of 267 participants from these health care systems responded to a structured questionnaire. The proportion of health care workers with good knowledge, attitudes and practices was respectively 71.9%, 94% and 50.2%. Factors associated with good knowledge of EVD were male [Adjusted Odds Ratio (AOR): 1.7: 95% CI 1.0 to 2.9] and received training in EVD (2.7: 1.6-4.8). Factors associated with good practice were membership in INSE (2.3: 1.1-4.7) and training on EVD (2.2: 1.3-3.8). There is lack of knowledge of EVD, as well as negative attitudes and practices, particularly in prevention. However, continuing education for health care workers could correct these deficiencies.

Published
2018
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12. Malaria in Guinean Rural Areas: Prevalence, Management, and Ethnotherapeutic Investigations in Dionfo, Sub-Prefecture of Labe#.

Author

Baldé, Aliou Mamadou, Balde, Alpha Oumar, Bah, Bilo, Barry, Halimatou, Traore, Saidou, Bah, Fatoumata, Balde, Mamadou Aliou, Camara, Aissata, Traore, Mohamed Sahar, Balde, Elhadj Saidou, Sylla, Ibrahima Kalil, and Diallo, Sadou

Subjects
*PHYTOTHERAPY, *MALARIA prevention, *DRUG therapy for malaria, *PROTOZOA, *DRUG efficacy, *EVALUATION of human services programs, *RURAL conditions, *POPULATION geography, *TREATMENT duration, *MALARIA, *ETHNOLOGY research, *TRADITIONAL medicine, *COMMUNITY-based social services, *DISEASE prevalence, *ANTIMALARIALS
Abstract

As part of a validation program of antimalarial traditional recipes, an ethnotherapeutic approach was applied in Dionfo, a meso-endemic Guinean rural area where conventional health facilities are insufficient. A prevalence investigation indicated a malarial burden of 4.26%. Ethnomedical and ethnobotanical surveys led to a collection of 63 plant species used against malaria from which Terminalia albida (Combretaceae) was one of the most cited. Ethnotherapeutic evaluation of a remedy based on T. albida was applied to 9 voluntary patients suffering from uncomplicated malaria. Treatment of 7 to 14 days led to an improvement of clinical symptoms and a complete parasite clearance achievement of 8/9 patients without side effects. In addition to antiplasmodial activity in vitro and in vivo previously described, this study indicates an efficacy to support the antimalarial traditional use of T. albida , which could constitute a first-aid treatment when access to other medicines is delayed in the Dionfo community. Ethnotherapeutical investigation could be a valuable approach to guide subsequent investigations on traditional remedies. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
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