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164 results on '"Trudzinski, F."'

1. Statins did not reduce the frequency of exacerbations in individuals with COPD and cardiovascular comorbidities in the COSYCONET cohort

Author

Frantzi, N., Nguyen, X. P., Herr, C., Alter, P., Söhler, S., Soriano, D., Watz, H., Waschki, B., Trinkmann, F., Eichenlaub, M., Trudzinski, F. C., Michels-Zetsche, J. D., Omlor, A., Seiler, F., Moneke, I., Biertz, F., Rohde, G., Stolz, D., Welte, T., Kauczor, H. U., Kahnert, K., Jörres, R. A., Vogelmeier, C. F., Bals, R., and Fähndrich, S.

Published
2024
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2. Midregional proatrial naturetic peptide (MRproANP) and copeptin (COPAVP) as predictors of all-cause mortality in recently diagnosed mild to moderate COPD—results from COSYCONET

Author

Fähndrich, S., Herr, C., Teuteberg, S., Alter, P., Söhler, S., Soriano, D., Classen, J., Adams, J., Weinhold, V., Watz, H., Waschki, B., Zeller, T., Eichenlaub, M., Trudzinski, F. C., Michels, J. D., Omlor, A., Seiler, F., Moneke, I., Biertz, F., Stolz, D., Welte, T., Kauczor, H. U., Kahnert, K., Jörres, R. A., Vogelmeier, C. F., and Bals, R.

Published
2024
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3. Association of Patients’ Knowledge on the Disease and Its Management with Indicators of Disease Severity and Individual Characteristics in Patients with Chronic Obstructive Pulmonary Disease (COPD): Results from COSYCONET 2

Author

Fischer C, Siakavara M, Alter P, Vogelmeier CF, Speicher T, Pott H, Watz H, Bals R, Trudzinski F, Herth F, Ficker JH, Wagner M, Lange C, Stoycheva K, Randerath W, Behr J, Fähndrich S, Welte T, Pink I, Kahnert K, Seeger W, Kuhnert S, Gessler T, Adaskina N, and Jörres RA

Subjects
copd, symptom exacerbation, patient acuity, education, knowledge, Medicine (General), R5-920
Abstract

Carolina Fischer,1,2 Maria Siakavara,1 Peter Alter,3 Claus Franz Vogelmeier,3 Tim Speicher,3 Hendrik Pott,4 Henrik Watz,5 Robert Bals,6,7 Franziska Trudzinski,8 Felix Herth,8 Joachim H Ficker,9 Manfred Wagner,9 Christoph Lange,10 Krista Stoycheva,10 Winfried Randerath,11 Jürgen Behr,12,13 Sebastian Fähndrich,14 Tobias Welte15 ,† Isabell Pink,15 Kathrin Kahnert,12,16 Werner Seeger,17 Stefan Kuhnert,17 Tobias Gessler,17 Nina Adaskina,18 Rudolf A Jörres1 1Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Bavaria, Germany; 2Department of Medicine I, Division of Respiratory Diseases, School of Medicine & Klinikum rechts der Isar, Technical University of Munich, Munich, Bavaria, Germany; 3Department of Medicine, Pulmonary, Critical Care and Sleep Medicine, Philipps University of Marburg (UMR), Member of the German Center for Lung Research (DZL), Marburg, Hesse, Germany; 4Section of Airway Infections, Department of Medicine, Pulmonary and Critical Care Medicine, Philipps University of Marburg (UMR), Marburg, Hesse, Germany; 5Pulmonary Research Institute at LungenClinic Grosshansdorf, Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Grosshansdorf, Schlewig-Holstein, Germany; 6Department of Internal Medicine V, Pulmonology, Allergology, Critical Care Medicine, Saarland University Hospital, Homburg, Saarland, Germany; 7Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarland University Campus, Saarbrücken, Saarland, Germany; 8Department of Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the Center for Lung Research (DZL), Heidelberg, Baden-Wuerttemberg, Germany; 9Department of Respiratory Medicine, Allergology and Sleep Medicine, Klinikum Nuremberg, Nürnberg, Bavaria, Germany; 10Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany; German Center for Infection Research (DZIF), Standort Hamburg-Lübeck-Borstel-Riems, Germany; Respiratory Medicine & International Health, University of Lübeck, Lübeck, Schleswig-Holstein, Germany; 11Krankenhaus Bethanien gGmbH, Klinik für Pneumologie und Allergologie, Zentrum für Schlaf- und Beatmungsmedizin, Solingen, North-Rhine Westphalia, Germany; 12Department of Medicine V, LMU University Hospital, LMU Munich, Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), Munich, Bavaria, Germany; 13Asklepios Fachkliniken München-Gauting, Gauting, Germany; 14Department of Pneumology, Faculty of Medicine, Medical Center, University of Freiburg, Baden-Wuerttemberg, Germany; 15Clinic for Pneumology, Hannover Medical School, Member of the German Center for Lung Research (DZL), Hannover, Lower Saxony, Germany; 16MediCenterGermering, Germering, Bavaria, Germany; 17University of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, Hesse, Germany; 18CAPNETZ STIFTUNG, Hannover, Lower Saxony, Germany†Tobias We

Published
2024

4. Endobronchial Valve Replacements in Patients with Advanced Emphysema After Endoscopic Lung Volume Reduction

Author

Brock JM, Schuster PU, Böhmker F, Eberhardt R, Gompelmann D, Kontogianni K, Trudzinski F, Benjamin N, and Herth F

Subjects
endobronchial lung volume reduction, endobronchial valves, valve replacement, revision bronchoscopy, copd, Diseases of the respiratory system, RC705-779
Abstract

Judith Maria Brock,1,2 Paul Ulrich Schuster,3 Felix Böhmker,3 Ralf Eberhardt,4 Daniela Gompelmann,5 Konstantina Kontogianni,1,2 Franziska Trudzinski,1,2 Nicola Benjamin,1 Felix Herth1,2 1Department of Pneumology and Critical Care Medicine, Thoraxklinik at University of Heidelberg, Heidelberg, Germany; 2Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany; 3Medical Faculty, University of Heidelberg, Heidelberg, Germany; 4Department of Pneumology and Intensive Care Medicine, Asklepios Klinik Barmbek, Hamburg, Germany; 5Department of Internal Medicine II, Division of Pulmonology, Medical University of Vienna, Vienna, AustriaCorrespondence: Judith Maria Brock, Department of Pneumology and Critical Care Medicine, Thoraxklinik Heidelberg, University Hospital of Heidelberg, Röntgenstraße 1, Heidelberg, 69126, Germany, Tel +49 6221-3968256, Email Judith.Brock@med.uni-heidelberg.dePurpose: Up to 41% of patients with endobronchial valve implantation need revision bronchoscopies and valve replacements most likely due to valve dysfunction or lack of benefit. So far, no data is available whether valve replacements lead to the desired lobar volume reduction and therapy benefit.Patients and Methods: We conducted a single-center retrospective analysis of patients with endobronchial valve implantation and at least one valve replacement. Indications and number of revision bronchoscopies and valve replacements were evaluated. Therapy benefit regarding lung function and exercise capacity as well as development of complete lobar atelectasis was investigated and possible predictors identified.Results: We identified 73 patients with 1– 12 revision bronchoscopies and 1– 5 valve replacements. The main indication for revision bronchoscopy in this group was lack of therapy benefit (44.2%). Lung function and exercise capacity showed improvements in about one-third of patients even years after the initial implantation. A total of 26% of all patients showed a complete lobar atelectasis at the end of the observation period, 56.2% had developed lung volume reduction. The logistic regression revealed the development of a previous complete lobar atelectasis as predictor for a complete lobar atelectasis at final follow-up. Oral cortisone long-term therapy was also shown as predictive factor. The probability for a final complete lobar atelectasis was 69.2% if a lobar atelectasis had developed before.Conclusion: Valve replacements are more likely to be beneficial in patients who develop a re-aeration of a previous lobar atelectasis following valve implantation. Every decision for revision bronchoscopy must be taken carefully.Keywords: endobronchial lung volume reduction, endobronchial valves, valve replacement, revision bronchoscopy, COPD

Published
2023

9. Effects of triple therapy in patients of GOLD group C and D: Results from the observational COPD cohort COSYCONET

Author

Zader, J, additional, Jörres, R, additional, Mayer, I, additional, Alter, P, additional, Bals, R, additional, Watz, H, additional, Mertsch, P, additional, Rabe, K, additional, Herth, F, additional, Trudzinski, F, additional, Welte, T, additional, Kauczor, H, additional, Behr, J, additional, Walter, J, additional, Vogelmeier, C, additional, and Kahnert, K, additional

Published
2023
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10. Erste Erfahrungen zum Einsatz eines E-learning Angebotes zur Verbesserung der Weaning-Kompetenz im Rahmen der PRiVENT-Intervention

Author

Trudzinski, F, additional, Schubert-Haack, J, additional, Neetz, B, additional, Tanck, K, additional, Iberl, G, additional, Müeller, M, additional, Kempa, A, additional, Neurohr, C, additional, Forstner, J, additional, Ghiani, A, additional, Andritschky, C, additional, Schneider, A, additional, Rheinhold, A, additional, Gehrig, P, additional, Szecsenyi, J, additional, and Herth, F, additional

Published
2023
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18. COVID-19-disease prevalence and its characteristics among health care workers of specialized respiratory clinics in Germany one year after the start of vaccination campaign

Author

Presotto, M A, primary, Piel, S, additional, Jörres, R A, additional, Karrasch, S, additional, Gesierich, W, additional, Bullwinkel, J, additional, Rabe, K F, additional, Hayden, M, additional, Kaestner, F, additional, Harzheim, D, additional, Joves, B, additional, Kempa, A T, additional, Ghiani, A, additional, Neurohr, C, additional, Kreuter, M, additional, Herth, F J F, additional, and Trudzinski, F C, additional

Published
2022
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19. Risk factors for pandemic-related workplace absenteeism among health care workers and the impact of vaccination

Author

Piel, S, primary, Presotto, M A, additional, Jörres, R A, additional, Karrasch, S, additional, Gesierich, W, additional, Bullwinkel, J, additional, Rabe, K F, additional, Hayden, M, additional, Kaestner, F, additional, Harzheim, D, additional, Joves, B, additional, Kempa, A T, additional, Ghiani, A, additional, Neurohr, C, additional, Kreuter, M, additional, Herth, F J, additional, and Trudzinski, F C, additional

Published
2022
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21. Proadrenomedullin and copeptin are more sensitive and specific biomarkers for the prediction of mortality in stable COPD than fibrinogen: An analysis of the COSYCONET study

Author

Fähndrich, S, primary, Teuteberg, S, additional, Herr, C, additional, Watz, H, additional, Waschki, B, additional, Trudzinski, F C, additional, Omlor, A, additional, Alter, P, additional, Seiler, F, additional, Biertz, F, additional, Welte, T, additional, Kauczor, H, additional, Jörres, R A, additional, Vogelmeier, C F, additional, Bals, R, additional, and Stolz, D, additional

Published
2022
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23. Factors underlying the increasing prevalence of comorbidities over time and their mutual relationship in COPD: Results from COSYCONET

Author

Alter, P, primary, Kahnert, K, additional, Trudzinski, F C, additional, Bals, R, additional, Watz, H, additional, Speicher, T, additional, Söhler, S, additional, Andreas, S, additional, Welte, T, additional, Rabe, K F, additional, Wouters, E F, additional, Lange, C, additional, Wirtz, H, additional, Ficker, J H, additional, Vogelmeier, C F, additional, and Jörres, R A, additional

Published
2022
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25. EP08.01-031 Blood Gene Expression Changes in Metastatic Lung Cancer under second-line Immunotherapy according to Clinical Response

Author

Lusky, F., primary, Schindler, H., additional, Elshiaty, M., additional, Gaissmaier, L., additional, Daniello, L., additional, Bozorgmehr, F., additional, Kuon, J., additional, Shah, R., additional, Schneider, M.A., additional, Eichhorn, F., additional, Trudzinski, F., additional, Angeles, A., additional, Janke, F., additional, Kirchner, M., additional, Kazdal, D., additional, Stenzinger, A., additional, Sültmann, H., additional, Thomas, M., additional, and Christopoulos, P., additional

Published
2022
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28. AB0685 Oxygenated hemoglobin as prognostic marker among patients with systemic sclerosis screened for pulmonary hypertension

Author

Xanthouli, P., primary, Gordjani, O., additional, Eichstaedt, C., additional, Benjamin, N., additional, Trudzinski, F., additional, Egenlauf, B., additional, Harutyunova, S., additional, Marra, A., additional, Milde, N., additional, Nagel, C., additional, Blank, N., additional, Lorenz, H. M., additional, and Grünig, E., additional

Published
2022
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32. Prädiktoren von Mortalität und Exazerbationen bei Patienten mit stabiler COPD: Ergebnisse von COSYCONET

Author

Alter, P, additional, Lucke, T, additional, Watz, H, additional, Andreas, S, additional, Kahnert, K, additional, Trudzinski, F C, additional, Speicher, T, additional, Söhler, S, additional, Bals, R, additional, Waschki, B, additional, Welte, T, additional, Rabe, K F, additional, Vestbo, J, additional, EFM, Wouters, additional, Vogelmeier, C F, additional, and Jörres, R A, additional

Published
2022
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35. Risikofaktoren für eine invasive Langzeitbeatmung – ein Systematic Literature Review

Author

Trudzinski, F C, additional, Bornitz, F, additional, Müller, M M, additional, Weis, A, additional, Neetz, B, additional, Kronsteiner, D, additional, FJF, Herth, additional, Sturm, N, additional, Gassmann, V, additional, Joveš, B, additional, Neurohr, C, additional, Ghiani, A, additional, Schneider, A, additional, Szecsenyi, J, additional, von Schumann, S, additional, and Meis, J, additional

Published
2022
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37. Geschlechtsspezifische Unterschiede des Komorbidoms und des Pulmorbidoms im Hinnblick auf die Prognose der COPD: Ergebnisse von COSYCONET

Author

Trudzinski, F C, additional, Jörres, R A, additional, Alter, P, additional, Walter, J, additional, Watz, H, additional, Koch, A, additional, John, M, additional, Lommatzsch, M, additional, Vogelmeier, C F, additional, Kauczor, H U, additional, Welte, T, additional, Behr, J, additional, Tufman, A, additional, Bals, R, additional, Herth, FJ F, additional, and Kahnert, K, additional

Published
2022
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38. Quality of life 3 and 12 months following acute pulmonary embolism analysis from a prospective multicenter cohort study

Author

Valerio, L., Barco, S., Jankowski, M., Rosenkranz, S., Lankeit, M., Held, M., Gerhardt, F., Bruch, L., Ewert, R., Faehling, M., Freise, J., Ghofrani, H.A., Grunig, E., Halank, M., Hoeper, M.M., Klok, F.A., Leuchte, H.H., Mayer, E., Meyer, F.J., Neurohr, C., Opitz, C., Schmidt, K.H., Seyfarth, H.J., Trudzinski, F., Wachter, R., Wilkens, H., Wild, P.S., and Konstantinides, S.V.

Subjects
Male, Time Factors, pulmonary embolism, Middle Aged, Prognosis, humanities, Survival Rate, quality of life, 5D-5L, patient-reported outcomes, Germany, Surveys and Questionnaires, patient-centered outcomes, PeMB-QoL, Acute Disease, Humans, Female, Prospective Studies, VTE, Aged, Follow-Up Studies
Abstract

Few data are available on the long-term course and predictors of quality of life (QoL) following acute pulmonary embolism (PE).What are the kinetics and determinants of disease-specific and generic health-related QoL 3 and 12 months following an acute PE?The Follow-up after Acute Pulmonary Embolism (FOCUS) study prospectively followed up consecutive adult patients with objectively diagnosed PE. Patients were considered for study who completed the Pulmonary Embolism Quality of Life (PEmb-QoL) questionnaire at predefined visits 3 and 12 months following PE. The course of disease-specific QoL as assessed using the PEmb-QoL and the impact of baseline characteristics using multivariable mixed effects linear regression were studied; also assessed was the course of generic QoL as evaluated by using the EuroQoL Group 5-Dimension 5-Level utility index and the EuroQoL Visual Analog Scale.In 620 patients (44% women; median age, 62 years), overall disease-specific QoL improved from 3 to 12 months, with a decrease in the median PEmb-QoL score from 19.4% to 13.0% and a mean individual change of -4.3% (95% CI, -3.2 to -5.5). Female sex, cardiopulmonary disease, and higher BMI were associated with worse QoL at both 3 and 12 months. Over time, the association with BMI became weaker, whereas older age and previous VTE were associated with worsening QoL. Generic QoL also improved: the mean ± SD EuroQoL Group 5-Dimension 5-Level utility index increased from 0.85 ± 0.22 to 0.87 ± 0.20 and the visual analog scale from 72.9 ± 18.8 to 74.4 ± 19.1.In a large cohort of survivors of acute PE, the change of QoL was quantified between months 3 and 12 following diagnosis, and factors independently associated with lower QoL and slower recovery of QoL were identified. This information may facilitate the planning and interpretation of clinical trials assessing QoL and help guide patient management.German Clinical Trials Registry (Deutsches Register Klinischer Studien: www.drks.de); No.: DRKS00005939.

Published
2021

41. Geschlechtsspezifische Unterschiede in der Symptomatik der COPD und deren Einfluss auf die Diagnostik kardialer Komorbiditäten

Author

Trudzinski, F C, additional, Kellerer, C, additional, Jörres, R, additional, Alter, P, additional, Lutter, J, additional, Trinkmann, F, additional, Herth, F JF, additional, Frankenberger, M, additional, Watz, H, additional, Vogelmeier, C F, additional, Kauczor, H U, additional, Welte, T, additional, Behr, J, additional, Bals, R, additional, and Kahnert, K, additional

Published
2021
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42. Functional outcomes and quality of life during long-term follow-up after acute pulmonary embolism: analysis of the prospective multicentre FOCUS study

Author

Barco, S, primary, Valerio, L, additional, Jankowski, M, additional, Hoeper, M.M, additional, Klok, F.A, additional, Leuchte, H.H, additional, Mayer, E, additional, Meyer, F.J, additional, Neurohr, C, additional, Opitz, C, additional, Seyfarth, H.J, additional, Trudzinski, F, additional, Wachter, R, additional, Wilkens, H, additional, and Wild, P.S, additional

Published
2020
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