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Your search keyword '"Trudzinski, F.C."' showing total 12 results
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12 results on '"Trudzinski, F.C."'

2. Impaired Left Ventricular Filling and All-cause Mortality in COPD

Author

Waschki, B., primary, Watz, H., additional, Alter, P., additional, Kahnert, K., additional, Trudzinski, F.C., additional, Groth, E., additional, Kirsten, A.-M., additional, Welte, T., additional, Jörres, R., additional, Vogelmeier, C.F., additional, Bals, R., additional, Rabe, K.F., additional, and Abdo, M., additional

Published
2024
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3. Combined effects of lung function, blood gases and kidney function on the exacerbation risk in stable COPD: Results from the COSYCONET cohort

Author

Stefan, Andreas, Robert, Bals, Jürgen, Behr, Kathrin, Kahnert, Burkhard, Bewig, Roland, Buhl, Ralf, Ewert, Beate, Stubbe, Joachim H, Ficker, Manfred, Gogol, Christian, Grohé, Rainer, Hauck, Matthias, Held, Berthold, Jany, Markus, Henke, Felix, Herth, Gerd, Höffken, Hugo A, Katus, Anne-Marie, Kirsten, Henrik, Watz, Rembert, Koczulla, Klaus, Kenn, Juliane, Kronsbein, Cornelia, Kropf-Sanchen, Christoph, Lange, Peter, Zabel, Michael, Pfeifer, Winfried J, Randerath, eeger Werner, Michael, Studnicka, Christian, Taube, Helmut, Teschler, Hartmut, Timmermann, Christian, Virchow J., Claus, Vogelmeier, Ulrich, Wagner, Tobias, Welte, Hubert, Wirtz, Trudzinski, F.C., Kahnert, K., Vogelmeier, C.F., Alter, P., Seiler, F., Fähndrich, S., Watz, H., Welte, T., Speer, T., Zewinger, S., Biertz, F., Kauczor, H.-U., Jörres, R.A., and Bals, R.

Published
2019
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4. Sex-Specific Associations of Comorbidome and Pulmorbidome with Mortality in Chronic Obstructive Pulmonary Disease: Results from COSYCONET

Author

Trudzinski, F.C., primary, Jörres, R., additional, Alter, P., additional, Walter, J., additional, Watz, H., additional, Koch, A., additional, John, M., additional, Lommatzsch, M., additional, Vogelmeier, C., additional, Kauczor, H.-U., additional, Welte, T., additional, Behr, J., additional, Tufman, A.L.H., additional, Bals, R., additional, Herth, F.J., additional, and Kahnert, K., additional

Published
2022
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6. Associations of oxygenated hemoglobin with disease burden and prognosis in stable COPD: Results from COSYCONET

Author

Trudzinski, F.C., Jörres, R.A., Alter, P., Kahnert, K., Waschki, B., Herr, C., Kellerer, C., Omlor, A., Vogelmeier, C.F., Fähndrich, S., Watz, H., Welte, T., Jany, B., Söhler, S., Biertz, F., Herth, F., Kauczor, H.-U., Bals, R., Andreas, Stefan, Behr, Jürgen, Bewig, Burkhard, Buhl, Roland, Ewert, Ralf, Stubbe, Beate, Ficker, Joachim H., Gogol, Manfred, Grohé, Christian, Hauck, Rainer, Held, Matthias, Henke, Markus, Höffken, Gerd, Katus, Hugo A., Kirsten, Anne-Marie, Koczulla, Rembert, Kenn, Klaus, Kronsbein, Juliane, Kropf-Sanchen, Lange, Christoph, Zabel, Peter, Pfeifer, Michael, Randerath, Winfried J., Seeger, Werner, Studnicka, Michael, Taube, Christian, Teschler, Helmut, Timmermann, Hartmut, Virchow, J. Christian, Wagner, and Wirtz, Hubert

Subjects
Adult, Male, medicine.medical_specialty, Exacerbation, Medizin, lcsh:Medicine, Severity of Illness Index, Gastroenterology, Article, Pulmonary Disease, Chronic Obstructive, 03 medical and health sciences, Medical research, 0302 clinical medicine, Internal medicine, medicine, Humans, 030212 general & internal medicine, Signs and symptoms, lcsh:Science, Survival rate, Aged, Oxygen saturation (medicine), Aged, 80 and over, Inflammation, COPD, Oxygenated Hemoglobin, Multidisciplinary, Proportional hazards model, business.industry, Hazard ratio, lcsh:R, Middle Aged, Prognosis, medicine.disease, Comorbidity, Survival Rate, Risk factors, 030228 respiratory system, Oxyhemoglobins, Female, lcsh:Q, Blood Gas Analysis, business, Biomarkers
Abstract

We studied whether in patients with stable COPD blood gases (BG), especially oxygenated hemoglobin (OxyHem) as a novel biomarker confer information on disease burden and prognosis and how this adds to the information provided by the comorbidity pattern and systemic inflammation. Data from 2137 patients (GOLD grades 1–4) of the baseline dataset of the COSYCONET COPD cohort were used. The associations with dyspnea, exacerbation history, BODE-Index (cut-off ≤2) and all-cause mortality over 3 years of follow-up were determined by logistic and Cox regression analyses, with sex, age, BMI and pack years as covariates. Predictive values were evaluated by ROC curves. Capillary blood gases included SaO2, PaO2, PaCO2, pH, BE and the concentration of OxyHem [haemoglobin (Hb) x fractional SaO2, g/dL] as a simple-to-measure correlate of oxygen content. Inflammatory markers were WBC, CRP, IL-6 and -8, TNF-alpha and fibrinogen, and comorbidities comprised a broad panel including cardiac and metabolic disorders. Among BG, OxyHem was associated with dyspnoea, exacerbation history, BODE-Index and mortality. Among inflammatory markers and comorbidities, only WBC and heart failure were consistently related to all outcomes. ROC analyses indicated that OxyHem provided information of a magnitude comparable to that of WBC, with optimal cut-off values of 12.5 g/dL and 8000/µL, respectively. Regarding mortality, OxyHem also carried independent, additional information, showing a hazard ratio of 2.77 (95% CI: 1.85–4.15, p 8000/µL was 2.33 (95% CI: 1.60–3.39, p 2. It thus appears well suited for clinical use with minimal equipment, especially for GPs.

Published
2020
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7. Gender-Specific Differences in COPD Symptoms and Their Impact for the Diagnosis of Cardiac Comorbidities: Results from COSYCONET

Author

Trudzinski, F.C., primary, Kellerer, C., additional, Jörres, R., additional, Alter, P., additional, Lutter, J.I., additional, Trinkmann, F., additional, Herth, F.J., additional, Frankenberger, M., additional, Watz, H., additional, Vogelmeier, C., additional, Kauczor, H.-U., additional, Welte, T., additional, Behr, J., additional, Bals, R., additional, and Kahnert, K., additional

Published
2021
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9. Associations of Blood Gases, Inflammatory Markers and Comorbidities with Disease Burden and Prognosis in Patients with Stable COPD: Results from Cosyconet

Author

Trudzinski, F.C., primary, Jörres, R., additional, Kahnert, K., additional, Alter, P., additional, Herr, C., additional, Kellerer, C., additional, Omlor, A., additional, Vogelmeier, C., additional, Herth, F., additional, Fähndrich, S.W., additional, Watz, H., additional, Welte, T., additional, Biertz, F., additional, kauczor, H.-U., additional, and Bals, R., additional

Published
2020
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10. Time-Updated Resting Heart Rate Predicts Mortality in Patients with COPD

Author

Omlor, A., primary, Trudzinski, F.C., additional, Alqudrah, M., additional, Seiler, F., additional, Biertz, F., additional, Vogelmeier, C., additional, Welte, T., additional, Watz, H., additional, Waschki, B., additional, Brinker, T., additional, Andreas, S., additional, Fähndrich, S.W., additional, Alter, P., additional, Jörres, R., additional, Böhm, M., additional, and Bals, R., additional

Published
2020
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12. Combined Effects of Lung Function, Blood Gases and Renal Function on Exacerbations in Stable COPD: Data from the Cosyconet Cohort

Author

Trudzinski, F.C., primary, Kahnert, K., additional, Vogelmeier, C., additional, Alter, P., additional, Seiler, F., additional, Fändrich, S., additional, Watz, H., additional, Welte, T., additional, Speer, T., additional, Fliser, D., additional, Zewinger, S., additional, Biertz, F., additional, Kauczor, H.-U., additional, Koch, A., additional, Jörres, R., additional, and Bals, R., additional

Published
2019
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