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1. Health inequities and the inappropriate use of race in nephrology

Author

Eneanya, Nwamaka D, Boulware, L Ebony, Tsai, Jennifer, Bruce, Marino A, Ford, Chandra L, Harris, Christina, Morales, Leo S, Ryan, Michael J, Reese, Peter P, Thorpe, Roland J, Morse, Michelle, Walker, Valencia, Arogundade, Fatiu A, Lopes, Antonio A, and Norris, Keith C

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Kidney Disease, Generic health relevance, Good Health and Well Being, Health Inequities, Health Status Disparities, Humans, Nephrology, Racism, Social Justice, United States, Urology & Nephrology, Clinical sciences
Abstract

Chronic kidney disease is an important clinical condition beset with racial and ethnic disparities that are associated with social inequities. Many medical schools and health centres across the USA have raised concerns about the use of race - a socio-political construct that mediates the effect of structural racism - as a fixed, measurable biological variable in the assessment of kidney disease. We discuss the role of race and racism in medicine and outline many of the concerns that have been raised by the medical and social justice communities regarding the use of race in estimated glomerular filtration rate equations, including its relationship with structural racism and racial inequities. Although race can be used to identify populations who experience racism and subsequent differential treatment, ignoring the biological and social heterogeneity within any racial group and inferring innate individual-level attributes is methodologically flawed. Therefore, although more accurate measures for estimating kidney function are under investigation, we support the use of biomarkers for determining estimated glomerular filtration rate without adjustments for race. Clinicians have a duty to recognize and elucidate the nuances of racism and its effects on health and disease. Otherwise, we risk perpetuating historical racist concepts in medicine that exacerbate health inequities and impact marginalized patient populations.

Published
2022

6. The Sacred Act of Remembering.

Author

Tsai, Jennifer Lee

Subjects
LOVE poetry, POETRY collections, MEMORY, GRIEF, EMPATHY, CATHARSIS, WOMEN poets, MEMOIRS, AUTOBIOGRAPHY
Abstract

This article is an interview with Hala Alyan, a licensed clinical psychologist, professor, and writer. Alyan discusses her latest poetry collection, "The Moon That Turns You Back," and the themes of witness, catharsis, and commemoration in her poetry. She explores the role of the poet in making sense of the world through language and the function of poetry in fortifying and centering us during times of suffering. Alyan also discusses her connection to Gaza and the tragedy of Palestine, as well as the use of form and the influence of her grandmother in her work. The interview is conducted by Jennifer Lee Tsai, a poet, artist, critic, and teacher. [Extracted from the article]

Published
2024

8. Historical Redlining and Present-Day Nonsuicide Firearm Fatalities.

Author

Dholakia, Ayesha, Burdick, Kendall J., Kreatsoulas, Catherine, Monuteaux, Michael C., Tsai, Jennifer, Subramanian, S.V., and Fleegler, Eric W.

Subjects
FIREARM fatalities, MAP design, ACHIEVEMENT gains (Education), POLICE reports, SHOOTINGS (Crime)
Abstract

Redlining began in the 1930s with the Home Owners' Loan Corporation; this discriminatory practice limited mortgage availability and reinforced concentrated poverty that still exists today. This study examines the relationship between historical redlining policies and present-day nonsuicide firearm fatalities. Visual Abstract. Historical Redlining and Present-Day Nonsuicide Firearm Fatalities: Redlining began in the 1930s with the Home Owners' Loan Corporation; this discriminatory practice limited mortgage availability and reinforced concentrated poverty that still exists today. This study examines the relationship between historical redlining policies and present-day nonsuicide firearm fatalities. Background: Redlining began in the 1930s with the Home Owners' Loan Corporation (HOLC); this discriminatory practice limited mortgage availability and reinforced concentrated poverty that still exists today. It is important to understand the potential health implications of this federally sanctioned segregation. Objective: To examine the relationship between historical redlining policies and present-day nonsuicide firearm fatalities. Design: Maps from the HOLC were overlaid with incidence of nonsuicide firearm fatalities from 2014 to 2022. A multilevel negative binomial regression model tested the association between modern-day firearm fatalities and HOLC historical grading (A ["best"] to D ["hazardous"]), controlling for year, HOLC area–level demographics, and state-level factors as fixed effects and a random intercept for city. Incidence rates (IRs) per 100 000 persons, incidence rate ratios (IRRs), and adjusted IRRs (aIRRs) for each HOLC grade were estimated using A-rated areas as the reference. Setting: 202 cities with areas graded by the HOLC in the 1930s. Participants: Population of the 8597 areas assessed by the HOLC. Measurements: Nonsuicide firearm fatalities. Results: From 2014 to 2022, a total of 41 428 nonsuicide firearm fatalities occurred in HOLC-graded areas. The firearm fatality rate increased as the HOLC grade progressed from A to D. In A-graded areas, the IR was 3.78 (95% CI, 3.52 to 4.05) per 100 000 persons per year. In B-graded areas, the IR, IRR, and aIRR relative to A areas were 7.43 (CI, 7.24 to 7.62) per 100 000 persons per year, 2.12 (CI, 1.94 to 2.32), and 1.42 (CI, 1.30 to 1.54), respectively. In C-graded areas, these values were 11.24 (CI, 11.08 to 11.40) per 100 000 persons per year, 3.78 (CI, 3.47 to 4.12), and 1.90 (CI, 1.75 to 2.07), respectively. In D-graded areas, these values were 16.26 (CI, 16.01 to 16.52) per 100 000 persons per year, 5.51 (CI, 5.05 to 6.02), and 2.07 (CI, 1.90 to 2.25), respectively. Limitation: The Gun Violence Archive relies on media coverage and police reports. Conclusion: Discriminatory redlining policies from 80 years ago are associated with nonsuicide firearm fatalities today. Primary Funding Source: Fred Lovejoy Housestaff Research and Education Fund. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function

Author

Arda, H Efsun, Li, Lingyu, Tsai, Jennifer, Torre, Eduardo A, Rosli, Yenny, Peiris, Heshan, Spitale, Robert C, Dai, Chunhua, Gu, Xueying, Qu, Kun, Wang, Pei, Wang, Jing, Grompe, Markus, Scharfmann, Raphael, Snyder, Michael S, Bottino, Rita, Powers, Alvin C, Chang, Howard Y, and Kim, Seung K

Subjects
Biotechnology, Digestive Diseases, Pancreatic Cancer, Human Genome, Genetics, Diabetes, Rare Diseases, Cancer, Underpinning research, Aetiology, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Generic health relevance, Metabolic and endocrine, Adult, Aging, Cell Differentiation, Cell Separation, Child, Child, Preschool, Chromatin, Chromatin Immunoprecipitation, Diabetes Mellitus, Gene Expression Regulation, Developmental, Histone Code, Homeodomain Proteins, Humans, Infant, Insulin-Secreting Cells, Middle Aged, Transcription Factors, Transcriptome, Young Adult, Biochemistry and Cell Biology, Medical Biochemistry and Metabolomics, Endocrinology & Metabolism
Abstract

Intensive efforts are focused on identifying regulators of human pancreatic islet cell growth and maturation to accelerate development of therapies for diabetes. After birth, islet cell growth and function are dynamically regulated; however, establishing these age-dependent changes in humans has been challenging. Here, we describe a multimodal strategy for isolating pancreatic endocrine and exocrine cells from children and adults to identify age-dependent gene expression and chromatin changes on a genomic scale. These profiles revealed distinct proliferative and functional states of islet α cells or β cells and histone modifications underlying age-dependent gene expression changes. Expression of SIX2 and SIX3, transcription factors without prior known functions in the pancreas and linked to fasting hyperglycemia risk, increased with age specifically in human islet β cells. SIX2 and SIX3 were sufficient to enhance insulin content or secretion in immature β cells. Our work provides a unique resource to study human-specific regulators of islet cell maturation and function.

Published
2016

11. Swallows

Author

Tsai, Jennifer Lee

Published
2019

13. Negative Substance Use Consequences Associated with Noncondom Use among Male, but Not Female, Alternative High School Students

Author

Grigsby, Timothy J., Forster, Myriam, Tsai, Jennifer, Rohrbach, Louise A., and Sussman, Steve

Abstract

Background: Alternative (or continuation) high schools are institutions designed for students at risk for not graduating due to behavioral, educational, or medical problems. The present study explored the relationship between negative substance use consequences (eg, having trouble at school or work) and noncondom use in this at-risk population and whether these associations varied by sex. Methods: Participants (N = 1101; 62.9% Hispanic; M[subscript age] = 16.85) were sampled from 24 alternative high schools in California, and data were analyzed using cross-sectional multivariate logistic regression models. Results: We observed a relationship between the number of negative substance use consequences and probability of noncondom use at the last sexual encounter for boys (p < 0.001) but not girls (p > 0.05). There were significant associations between specific social consequences (missing school/work) and dependence symptoms (selling personal items to get alcohol or drugs) with noncondom use for boys only. There was a similar association between substance use frequency and noncondom use for boys. Conclusions: These findings suggest that substance use consequences may be a useful and advantageous indicator of risky sexual behaviors such as noncondom use for boys, but not girls, in alternative high school settings. Future research and intervention programming recommendations are discussed.

Published
2018
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14. Nrf2 regulates CD4+ T cell–induced acute graft-versus-host disease in mice

Author

Tsai, Jennifer J., Velardi, Enrico, Shono, Yusuke, Argyropoulos, Kimon V., Holland, Amanda M., Smith, Odette M., Yim, Nury L., Rao, Uttam K., Kreines, Fabiana M., Lieberman, Sophie R., Young, Lauren F., Lazrak, Amina, Youssef, Salma, Fu, Ya-Yuan, Liu, Chen, Lezcano, Cecilia, Murphy, George F., Na, Il-Kang, Jenq, Robert R., Hanash, Alan M., Dudakov, Jarrod A., and van den Brink, Marcel R.M.

Published
2018
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15. Using Critical Pedagogy to Advance Antiracism in Health Professions Education.

Author

Onuoha, Chioma, Tsai, Jennifer, and Khazanchi, Rohan

Subjects
*TEACHING methods, *ANTI-racism, *HOSPITAL medical staff, *CONCEPTUAL structures, *CLINICAL competence, *HEALTH equity, *MEDICAL education
Abstract

This article draws on Paulo Freire's Pedagogy of the Oppressed to model how health professions education can advance health equity. It first introduces 3 well-known frameworks that can be meaningfully applied as critical pedagogy: structural competency, critical race theory, and participatory action research. It then highlights applications of these frameworks that can prepare trainees for reflection and action that motivate health equity. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Contributors

Author

Badayai, Abdul Rahman Ahmad, primary, Basri, Nadzirah Ahmad, additional, Champion, Katrina, additional, Chen, Yoke Yong, additional, Dash, Genevieve F., additional, Degenhardt, Louisa, additional, Delfabbro, Paul H., additional, Essau, Cecilia A., additional, Feldstein Ewing, Sarah W., additional, Furtado, Jessica, additional, Hall, Wayne, additional, Head, Sarah, additional, Hinze, Cecilie Juul, additional, Hutchinson, Delyse, additional, King, Daniel L., additional, Leung, Janni, additional, Lichtenstein, Mia Beck, additional, Long, Dennis, additional, McArdle, Paul, additional, Newton, Nicola C., additional, Preyde, Michèle, additional, Silvers, Jennifer A., additional, Sussman, Steve, additional, Teague, Samantha, additional, Thomsen, Kristine Rømer, additional, Ting, Chuong Hock, additional, Tsai, Jennifer Y., additional, and Wahab, Suzaily, additional

Published
2020
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20. Journeying : young children’s responses to picture books of traumatic and sensitive issues

Author

Tsai, Jennifer Pei-Miao

Subjects
370.15, LB1501 Primary Education
Abstract

This study investigates the response of a class of 35 seven and eight year old children to ten picture books with difficult, traumatic subject matter. Two of the stories deal with areas of emotional loss, including the death of a grandfather; five stories take the area of the Holocaust as their central theme, and three are stories of earthquakes, with the consequent loss of life and destruction. My research findings contribute to the study of children’s literature in education by uniquely analysing and giving insight into especially young children’s responses to this particular genre of children’s literature. In this research programme, the children are invited to engage in reading and four designed activities emerged for response: the central importance of spoken language, the place of writing to capture meaning and significance, the value of drawing to enhance understanding and the place of imaginative role play as children worked on their impressions of events in the stories. My central research questions are: What is young children’s understanding of and response to texts and pictures in selected children’s picture books of trauma? In what ways might young children’s responses to these issues and their accompanying activities reshape their critical thinking? What have I, as the researcher, learnt about my role as a teacher through teaching traumatic issues? The study was conducted in Taiwan using participatory action research methods. My evidence shows that these children are capable of understanding complex and disturbing situations that underpin the picture book narratives. They used their social, interactive, verbal, emotional and imaginative skills to respond to the texts in powerful ways. The significance of the teacher’s role as a listener, questioner and learner was crucial in helping to motive and engage the children. The study’s findings are that picture books that deal with disturbing human issues can be introduced as part of a planned programme of Arts and Life education in Grades 1 to 6 of the primary school curriculum and that children as young as seven are capable of responding to them with maturity and sophistication.

Published
2010

23. Data from A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

Author

Shono, Yusuke, primary, Tuckett, Andrea Z., primary, Ouk, Samedy, primary, Liou, Hsiou-Chi, primary, Altan-Bonnet, Grégoire, primary, Tsai, Jennifer J., primary, Oyler, Jennifer E., primary, Smith, Odette M., primary, West, Mallory L., primary, Singer, Natalie V., primary, Doubrovina, Ekaterina, primary, Pankov, Dmitry, primary, Undhad, Chandresh V., primary, Murphy, George F., primary, Lezcano, Cecilia, primary, Liu, Chen, primary, O'Reilly, Richard J., primary, van den Brink, Marcel R.M., primary, and Zakrzewski, Johannes L., primary

Published
2023
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24. Supplementary Figure 5 from A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

Author

Shono, Yusuke, primary, Tuckett, Andrea Z., primary, Ouk, Samedy, primary, Liou, Hsiou-Chi, primary, Altan-Bonnet, Grégoire, primary, Tsai, Jennifer J., primary, Oyler, Jennifer E., primary, Smith, Odette M., primary, West, Mallory L., primary, Singer, Natalie V., primary, Doubrovina, Ekaterina, primary, Pankov, Dmitry, primary, Undhad, Chandresh V., primary, Murphy, George F., primary, Lezcano, Cecilia, primary, Liu, Chen, primary, O'Reilly, Richard J., primary, van den Brink, Marcel R.M., primary, and Zakrzewski, Johannes L., primary

Published
2023
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25. Supplementary Figure 4 from A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

Author

Shono, Yusuke, primary, Tuckett, Andrea Z., primary, Ouk, Samedy, primary, Liou, Hsiou-Chi, primary, Altan-Bonnet, Grégoire, primary, Tsai, Jennifer J., primary, Oyler, Jennifer E., primary, Smith, Odette M., primary, West, Mallory L., primary, Singer, Natalie V., primary, Doubrovina, Ekaterina, primary, Pankov, Dmitry, primary, Undhad, Chandresh V., primary, Murphy, George F., primary, Lezcano, Cecilia, primary, Liu, Chen, primary, O'Reilly, Richard J., primary, van den Brink, Marcel R.M., primary, and Zakrzewski, Johannes L., primary

Published
2023
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26. Supplementary Figure 3 from A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

Author

Shono, Yusuke, primary, Tuckett, Andrea Z., primary, Ouk, Samedy, primary, Liou, Hsiou-Chi, primary, Altan-Bonnet, Grégoire, primary, Tsai, Jennifer J., primary, Oyler, Jennifer E., primary, Smith, Odette M., primary, West, Mallory L., primary, Singer, Natalie V., primary, Doubrovina, Ekaterina, primary, Pankov, Dmitry, primary, Undhad, Chandresh V., primary, Murphy, George F., primary, Lezcano, Cecilia, primary, Liu, Chen, primary, O'Reilly, Richard J., primary, van den Brink, Marcel R.M., primary, and Zakrzewski, Johannes L., primary

Published
2023
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27. Supplementary Figure 6 from A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

Author

Shono, Yusuke, primary, Tuckett, Andrea Z., primary, Ouk, Samedy, primary, Liou, Hsiou-Chi, primary, Altan-Bonnet, Grégoire, primary, Tsai, Jennifer J., primary, Oyler, Jennifer E., primary, Smith, Odette M., primary, West, Mallory L., primary, Singer, Natalie V., primary, Doubrovina, Ekaterina, primary, Pankov, Dmitry, primary, Undhad, Chandresh V., primary, Murphy, George F., primary, Lezcano, Cecilia, primary, Liu, Chen, primary, O'Reilly, Richard J., primary, van den Brink, Marcel R.M., primary, and Zakrzewski, Johannes L., primary

Published
2023
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28. Supplementary Figure 1 from A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

Author

Shono, Yusuke, primary, Tuckett, Andrea Z., primary, Ouk, Samedy, primary, Liou, Hsiou-Chi, primary, Altan-Bonnet, Grégoire, primary, Tsai, Jennifer J., primary, Oyler, Jennifer E., primary, Smith, Odette M., primary, West, Mallory L., primary, Singer, Natalie V., primary, Doubrovina, Ekaterina, primary, Pankov, Dmitry, primary, Undhad, Chandresh V., primary, Murphy, George F., primary, Lezcano, Cecilia, primary, Liu, Chen, primary, O'Reilly, Richard J., primary, van den Brink, Marcel R.M., primary, and Zakrzewski, Johannes L., primary

Published
2023
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29. Supplementary Figure 2 from A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

Author

Shono, Yusuke, primary, Tuckett, Andrea Z., primary, Ouk, Samedy, primary, Liou, Hsiou-Chi, primary, Altan-Bonnet, Grégoire, primary, Tsai, Jennifer J., primary, Oyler, Jennifer E., primary, Smith, Odette M., primary, West, Mallory L., primary, Singer, Natalie V., primary, Doubrovina, Ekaterina, primary, Pankov, Dmitry, primary, Undhad, Chandresh V., primary, Murphy, George F., primary, Lezcano, Cecilia, primary, Liu, Chen, primary, O'Reilly, Richard J., primary, van den Brink, Marcel R.M., primary, and Zakrzewski, Johannes L., primary

Published
2023
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30. Supplementary Table 1 and Table 2 from A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

Author

Shono, Yusuke, primary, Tuckett, Andrea Z., primary, Ouk, Samedy, primary, Liou, Hsiou-Chi, primary, Altan-Bonnet, Grégoire, primary, Tsai, Jennifer J., primary, Oyler, Jennifer E., primary, Smith, Odette M., primary, West, Mallory L., primary, Singer, Natalie V., primary, Doubrovina, Ekaterina, primary, Pankov, Dmitry, primary, Undhad, Chandresh V., primary, Murphy, George F., primary, Lezcano, Cecilia, primary, Liu, Chen, primary, O'Reilly, Richard J., primary, van den Brink, Marcel R.M., primary, and Zakrzewski, Johannes L., primary

Published
2023
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32. Comparative Analyses of Potato Expressed Sequence Tag Libraries

Author

Ronning, Catherine M., White, Joseph A., Cho, Jennifer, Tsai, Jennifer, Quackenbush, John, Smart, Christine D., Fry, William E., Tanksley, Steve, Zhang, Peifen, Jin, Hailing, Yamamoto, Miki L., Baker, Barbara J., and Buell, C. Robin

Published
2003

34. Age-related epithelial defects limit thymic function and regeneration

Author

Kousa, Anastasia I., Jahn, Lorenz, Zhao, Kelin, Flores, Angel E., Acenas, Dante, Lederer, Emma, Argyropoulos, Kimon V., Lemarquis, Andri L., Granadier, David, Cooper, Kirsten, D’Andrea, Michael, Sheridan, Julie M., Tsai, Jennifer, Sikkema, Lisa, Lazrak, Amina, Nichols, Katherine, Lee, Nichole, Ghale, Romina, Malard, Florent, Andrlova, Hana, Velardi, Enrico, Youssef, Salma, Burgos da Silva, Marina, Docampo, Melissa, Sharma, Roshan, Mazutis, Linas, Wimmer, Verena C., Rogers, Kelly L., DeWolf, Susan, Gipson, Brianna, Gomes, Antonio L. C., Setty, Manu, Pe’er, Dana, Hale, Laura, Manley, Nancy R., Gray, Daniel H. D., van den Brink, Marcel R. M., and Dudakov, Jarrod A.

Abstract

The thymus is essential for establishing adaptive immunity yet undergoes age-related involution that leads to compromised immune responsiveness. The thymus is also extremely sensitive to acute insult and although capable of regeneration, this capacity declines with age for unknown reasons. We applied single-cell and spatial transcriptomics, lineage-tracing and advanced imaging to define age-related changes in nonhematopoietic stromal cells and discovered the emergence of two atypical thymic epithelial cell (TEC) states. These age-associated TECs (aaTECs) formed high-density peri-medullary epithelial clusters that were devoid of thymocytes; an accretion of nonproductive thymic tissue that worsened with age, exhibited features of epithelial-to-mesenchymal transition and was associated with downregulation of FOXN1. Interaction analysis revealed that the emergence of aaTECs drew tonic signals from other functional TEC populations at baseline acting as a sink for TEC growth factors. Following acute injury, aaTECs expanded substantially, further perturbing trophic regeneration pathways and correlating with defective repair of the involuted thymus. These findings therefore define a unique feature of thymic involution linked to immune aging and could have implications for developing immune-boosting therapies in older individuals.

Published
2024
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36. Prevalence and Co-Occurrence of Addictive Behaviors among Russian and Spanish Youth: A Replication Study

Author

Tsai, Jennifer, Huh, Jimi, Idrisov, Bulat, Galimov, Artur, Espada, Jose P., Gonzálvez, María T., and Sussman, Steve

Abstract

Recently, an addiction matrix measure was assessed among U.S. former alternative high school youth. This presentation seeks to examine the generalizability of findings using this measure among Russian and Spanish high school adolescents. Latent class analysis was used to explore addiction subgroups among adolescents in Russia (average age = 16.27; n = 715) and Spain (average age = 14.9; n = 811). Last 30-day prevalence of one or more of 11 addictions reviewed in the previous work was the primary focus (i.e., cigarettes, alcohol, hard drugs, eating, gambling, Internet, love, sex, exercise, work, and shopping) among Russian youth, and last-30 prevalence of one or more of 8 addictions among Spanish youth (the three drug use items had not been included in the questionnaire for these youths). Results confirmed a two-class model (addicted class and non-addicted class) among both Russian and Spanish adolescents. The mean number of addictions reported was 1.39 (SD = 1.78) addictions among Russian youth and 1.56 (SD = 1.68) addictions among Spanish youth. The prevalence of the sample that constituted the "addicted group" in Russia and Spain was 32.2% and 28.6%, respectively. The most prevalent addictions (i.e., love, Internet, exercise) were similar. These results are similar to the findings previously reported for U.S. sample. Latent class structures for addictive behaviors are similar across international adolescent populations. Our results highlight the need to address multiple addictions in health education programming.

Published
2016
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38. Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury

Author

Velardi, Enrico, Tsai, Jennifer J, Radtke, Stefan, Cooper, Kirsten, Argyropoulos, Kimon V, Jae-Hung, Shieh, Young, Lauren F, Lazrak, Amina, Smith, Odette M, Lieberman, Sophie, Kreines, Fabiana, Shono, Yusuke, Wertheimer, Tobias, Jenq, Robert R, Hanash, Alan M, Narayan, Prema, Lei, Zhenmin, Moore, Malcolm A, Kiem, Hans-Peter, van den Brink, Marcel R M, and Dudakov, Jarrod A

Subjects
Hematopoietic stem cells -- Physiological aspects -- Genetic aspects -- Research, Bone marrow diseases -- Genetic aspects -- Care and treatment -- Research, Luteinizing hormone -- Physiological aspects -- Genetic aspects -- Research, Biological sciences, Health
Abstract

Author(s): Enrico Velardi (corresponding author) [1, 2]; Jennifer J Tsai [1, 3, 4]; Stefan Radtke [5, 6]; Kirsten Cooper [3, 4]; Kimon V Argyropoulos [1]; Shieh Jae-Hung [7]; Lauren F [...]

Published
2018
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39. Supplementary Figure S7 from H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma

Author

Joshi, Jaya Julie, primary, Coffey, Heather, primary, Corcoran, Erik, primary, Tsai, Jennifer, primary, Huang, Chia-Ling, primary, Ichikawa, Kana, primary, Prajapati, Sudeep, primary, Hao, Ming-Hong, primary, Bailey, Suzanna, primary, Wu, Jeremy, primary, Rimkunas, Victoria, primary, Karr, Craig, primary, Subramanian, Vanitha, primary, Kumar, Pavan, primary, MacKenzie, Crystal, primary, Hurley, Raelene, primary, Satoh, Takashi, primary, Yu, Kun, primary, Park, Eunice, primary, Rioux, Nathalie, primary, Kim, Amy, primary, Lai, Weidong G., primary, Yu, Lihua, primary, Zhu, Ping, primary, Buonamici, Silvia, primary, Larsen, Nicholas, primary, Fekkes, Peter, primary, Wang, John, primary, Warmuth, Markus, primary, Reynolds, Dominic J., primary, Smith, Peter G., primary, and Selvaraj, Anand, primary

Published
2023
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40. Supplementary Table S2andS3 from H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma

Author

Joshi, Jaya Julie, primary, Coffey, Heather, primary, Corcoran, Erik, primary, Tsai, Jennifer, primary, Huang, Chia-Ling, primary, Ichikawa, Kana, primary, Prajapati, Sudeep, primary, Hao, Ming-Hong, primary, Bailey, Suzanna, primary, Wu, Jeremy, primary, Rimkunas, Victoria, primary, Karr, Craig, primary, Subramanian, Vanitha, primary, Kumar, Pavan, primary, MacKenzie, Crystal, primary, Hurley, Raelene, primary, Satoh, Takashi, primary, Yu, Kun, primary, Park, Eunice, primary, Rioux, Nathalie, primary, Kim, Amy, primary, Lai, Weidong G., primary, Yu, Lihua, primary, Zhu, Ping, primary, Buonamici, Silvia, primary, Larsen, Nicholas, primary, Fekkes, Peter, primary, Wang, John, primary, Warmuth, Markus, primary, Reynolds, Dominic J., primary, Smith, Peter G., primary, and Selvaraj, Anand, primary

Published
2023
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41. Data from H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma

Author

Joshi, Jaya Julie, primary, Coffey, Heather, primary, Corcoran, Erik, primary, Tsai, Jennifer, primary, Huang, Chia-Ling, primary, Ichikawa, Kana, primary, Prajapati, Sudeep, primary, Hao, Ming-Hong, primary, Bailey, Suzanna, primary, Wu, Jeremy, primary, Rimkunas, Victoria, primary, Karr, Craig, primary, Subramanian, Vanitha, primary, Kumar, Pavan, primary, MacKenzie, Crystal, primary, Hurley, Raelene, primary, Satoh, Takashi, primary, Yu, Kun, primary, Park, Eunice, primary, Rioux, Nathalie, primary, Kim, Amy, primary, Lai, Weidong G., primary, Yu, Lihua, primary, Zhu, Ping, primary, Buonamici, Silvia, primary, Larsen, Nicholas, primary, Fekkes, Peter, primary, Wang, John, primary, Warmuth, Markus, primary, Reynolds, Dominic J., primary, Smith, Peter G., primary, and Selvaraj, Anand, primary

Published
2023
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42. Supplementary Legends from H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma

Author

Joshi, Jaya Julie, primary, Coffey, Heather, primary, Corcoran, Erik, primary, Tsai, Jennifer, primary, Huang, Chia-Ling, primary, Ichikawa, Kana, primary, Prajapati, Sudeep, primary, Hao, Ming-Hong, primary, Bailey, Suzanna, primary, Wu, Jeremy, primary, Rimkunas, Victoria, primary, Karr, Craig, primary, Subramanian, Vanitha, primary, Kumar, Pavan, primary, MacKenzie, Crystal, primary, Hurley, Raelene, primary, Satoh, Takashi, primary, Yu, Kun, primary, Park, Eunice, primary, Rioux, Nathalie, primary, Kim, Amy, primary, Lai, Weidong G., primary, Yu, Lihua, primary, Zhu, Ping, primary, Buonamici, Silvia, primary, Larsen, Nicholas, primary, Fekkes, Peter, primary, Wang, John, primary, Warmuth, Markus, primary, Reynolds, Dominic J., primary, Smith, Peter G., primary, and Selvaraj, Anand, primary

Published
2023
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43. Data from PLZF Confers Effector Functions to Donor T Cells That Preserve Graft-versus-Tumor Effects while Attenuating GVHD

Author

Ghosh, Arnab, primary, Holland, Amanda M., primary, Dogan, Yildirim, primary, Yim, Nury L., primary, Rao, Uttam K., primary, Young, Lauren F., primary, West, Mallory L., primary, Singer, Natalie V., primary, Lee, Hae, primary, Na, Il-Kang, primary, Tsai, Jennifer J., primary, Jenq, Robert R., primary, Penack, Olaf, primary, Hanash, Alan M., primary, Lezcano, Cecilia, primary, Murphy, George F., primary, Liu, Chen, primary, Sadelain, Michel, primary, Sauer, Martin G., primary, Sant'Angelo, Derek, primary, and van den Brink, Marcel R.M., primary

Published
2023
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44. Data from Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB–Controlled Oxidative Stress Responses

Author

Shono, Yusuke, primary, Tuckett, Andrea Z., primary, Liou, Hsiou-Chi, primary, Doubrovina, Ekaterina, primary, Derenzini, Enrico, primary, Ouk, Samedy, primary, Tsai, Jennifer J., primary, Smith, Odette M., primary, Levy, Emily R., primary, Kreines, Fabiana M., primary, Ziegler, Carly G.K., primary, Scallion, Mary I., primary, Doubrovin, Mikhail, primary, Heller, Glenn, primary, Younes, Anas, primary, O'Reilly, Richard J., primary, van den Brink, Marcel R.M., primary, and Zakrzewski, Johannes L., primary

Published
2023
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45. Supplementary Figure 5 from Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB–Controlled Oxidative Stress Responses

Author

Shono, Yusuke, primary, Tuckett, Andrea Z., primary, Liou, Hsiou-Chi, primary, Doubrovina, Ekaterina, primary, Derenzini, Enrico, primary, Ouk, Samedy, primary, Tsai, Jennifer J., primary, Smith, Odette M., primary, Levy, Emily R., primary, Kreines, Fabiana M., primary, Ziegler, Carly G.K., primary, Scallion, Mary I., primary, Doubrovin, Mikhail, primary, Heller, Glenn, primary, Younes, Anas, primary, O'Reilly, Richard J., primary, van den Brink, Marcel R.M., primary, and Zakrzewski, Johannes L., primary

Published
2023
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46. Supplementary Figure 2 from Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB–Controlled Oxidative Stress Responses

Author

Shono, Yusuke, primary, Tuckett, Andrea Z., primary, Liou, Hsiou-Chi, primary, Doubrovina, Ekaterina, primary, Derenzini, Enrico, primary, Ouk, Samedy, primary, Tsai, Jennifer J., primary, Smith, Odette M., primary, Levy, Emily R., primary, Kreines, Fabiana M., primary, Ziegler, Carly G.K., primary, Scallion, Mary I., primary, Doubrovin, Mikhail, primary, Heller, Glenn, primary, Younes, Anas, primary, O'Reilly, Richard J., primary, van den Brink, Marcel R.M., primary, and Zakrzewski, Johannes L., primary

Published
2023
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47. Supplementary Figure 11 from Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB–Controlled Oxidative Stress Responses

Author

Shono, Yusuke, primary, Tuckett, Andrea Z., primary, Liou, Hsiou-Chi, primary, Doubrovina, Ekaterina, primary, Derenzini, Enrico, primary, Ouk, Samedy, primary, Tsai, Jennifer J., primary, Smith, Odette M., primary, Levy, Emily R., primary, Kreines, Fabiana M., primary, Ziegler, Carly G.K., primary, Scallion, Mary I., primary, Doubrovin, Mikhail, primary, Heller, Glenn, primary, Younes, Anas, primary, O'Reilly, Richard J., primary, van den Brink, Marcel R.M., primary, and Zakrzewski, Johannes L., primary

Published
2023
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48. Supplementary Figure 9 from Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB–Controlled Oxidative Stress Responses

Author

Shono, Yusuke, primary, Tuckett, Andrea Z., primary, Liou, Hsiou-Chi, primary, Doubrovina, Ekaterina, primary, Derenzini, Enrico, primary, Ouk, Samedy, primary, Tsai, Jennifer J., primary, Smith, Odette M., primary, Levy, Emily R., primary, Kreines, Fabiana M., primary, Ziegler, Carly G.K., primary, Scallion, Mary I., primary, Doubrovin, Mikhail, primary, Heller, Glenn, primary, Younes, Anas, primary, O'Reilly, Richard J., primary, van den Brink, Marcel R.M., primary, and Zakrzewski, Johannes L., primary

Published
2023
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49. Supplementary Figure 7 from Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB–Controlled Oxidative Stress Responses

Author

Shono, Yusuke, primary, Tuckett, Andrea Z., primary, Liou, Hsiou-Chi, primary, Doubrovina, Ekaterina, primary, Derenzini, Enrico, primary, Ouk, Samedy, primary, Tsai, Jennifer J., primary, Smith, Odette M., primary, Levy, Emily R., primary, Kreines, Fabiana M., primary, Ziegler, Carly G.K., primary, Scallion, Mary I., primary, Doubrovin, Mikhail, primary, Heller, Glenn, primary, Younes, Anas, primary, O'Reilly, Richard J., primary, van den Brink, Marcel R.M., primary, and Zakrzewski, Johannes L., primary

Published
2023
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50. Supplementary Figure 8 from Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB–Controlled Oxidative Stress Responses

Author

Shono, Yusuke, primary, Tuckett, Andrea Z., primary, Liou, Hsiou-Chi, primary, Doubrovina, Ekaterina, primary, Derenzini, Enrico, primary, Ouk, Samedy, primary, Tsai, Jennifer J., primary, Smith, Odette M., primary, Levy, Emily R., primary, Kreines, Fabiana M., primary, Ziegler, Carly G.K., primary, Scallion, Mary I., primary, Doubrovin, Mikhail, primary, Heller, Glenn, primary, Younes, Anas, primary, O'Reilly, Richard J., primary, van den Brink, Marcel R.M., primary, and Zakrzewski, Johannes L., primary

Published
2023
Full Text
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