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1. Antiapoptotic Cdc42 mutants are potent activators of cellular transformation

Author

Tu, Shine S., Wu, Wen Jin, Yang, Wannian, Nolbant, Peri, Hahn, Klaus, and Cerione, Richard A.

Subjects
Biochemistry -- Research, Gene mutations -- Physiological aspects, Cells -- Genetic aspects, Carrier proteins -- Genetic aspects, Cell cycle -- Research, Biological sciences, Chemistry
Abstract

Research has been conducted on the Cdc42 mutant. The ability of this mutant to undergo GDP-GTP exchange, to resist caspase cleavage and to survive under apoptotic conditions has been investigated and discussed.

Published
2002

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